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Chunk #28 — Methods — H3K9Ac ChIP-Seq

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A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
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least 100 samples (~15%) was considered as part of an H3K9Ac domain. Domains within 100 bp distance were merged. Subsequently, H3K9Ac domains of less than 100 bp width were removed resulting in a total of 26,384 H3K9Ac domains with a median width of 2,829 bp. Finally, uniquely mapped unique reads were extended towards their 3′-end to the estimated fragment size, and the number of reads overlapping each domain was computed for each sample. In total, read count data and bam files are available for 712 subjects.