Genetic correlation of tail clip latency to genome-wide gene expression was performed for each of five brain tissues for which expression profiles across the BXD RI lines are in GeneNetwork, namely, whole brain, neocortex, striatum, cerebellum and hippocampus. Correlation results from each of the five brain regions were thresholded using a P-value of 0.001 to create coexpression candidate lists. All candidate gene lists obtained from interval mapping and genetic correlations were then uploaded into the ODE for combinatorial analysis. Maximum gene to measure (phenotype) connectivity was observed for Slfn5 or schlafen 5 (associated with positional candidates on Chr 11 for females, male cerebellum gene expression correlates and male striatum gene expression correlates) and Ankrd12 or ankyrin repeat domain 12 (associated with female cerebellum gene expression correlates, male cerebellum gene expression correlates and male hippocampus gene expression correlates). Other candidate genes in the interval were not found on this list of correlates, but include genes belonging to voltage-gated sodium (e.g. Scn2b and Scn4b, Tail Clip Male Positional candidates on Chr 4) or calcium channels class of genes (Bear et al. 2009),
