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Chunk #32 — 3. Results — 3.3. Secondary analyses — 3.3.1. CRHR1

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Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.
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Two SNPs, rs9900679 and rs4792887, were not in LD with any SNPs (Fig. 3, Fig. S1). Carriers of the rs9900679 variant allele that is unique to individuals of African ancestry (Table 1) were more likely not to have attempted suicide (0.07 vs 0.03; L-R χ2 = 7.4, 3 df, p = 0.007). This result survived Bonferroni correction.