This review has highlighted a number of interventions and strategies that have demonstrated some success for reducing stigma related to substance use disorders. The findings produced by the 13 included studies require replication, especially as many had small sample sizes, reported mixed results and used uncontrolled study designs. Until such time that there is a more robust body of evidence, it is recommended that these interventions be piloted and evaluated carefully to ascertain whether they are generalizable to different populations and contexts.