Regarding our variant-level ExWAS, upon construction of our variant matrices, which took 2,500 CPU hours to compile, all 108 billion statistical tests were calculated in 855,000 CPU hours. In wall-clock hours, this took 37 h to generate the variant matrices. Once these intermediate files were ready, the approximately 108 billion ExWAS statistical tests took 27 h for binary traits and 11 h for quantitative traits.
