In general, the reduced response to alcohol in FHP women was more modest compared to previous studies conducted in FHP men. Further, even though 50% of the FHP group consisted of moderate drinkers and these FHP women had higher densities of family histories of alcoholism and substance abuse, these factors among FHP women did not appear to substantially contribute or enhance the differences observed between FHP and FHN women. Taken together, these findings provide further support that the response to alcohol in FHP women is not identical to previous studies in FHP men and the factors that increase risk for developing alcoholism in women may be more complex.
