This study identified interaction effects of BMI and gender on predicting likelihood of lifetime and past-year alcohol use disorders and lifetime and past-year nicotine dependence. BMI was positively associated with lifetime risk for alcohol abuse and dependence in men and inversely associated with past-year risk in women. Overweight and obesity were associated with decreased odds for both lifetime and past-year nicotine dependence among men. Among women, overweight was associated with increased odds of lifetime nicotine dependence, and obesity was associated with decreased odds of past-year nicotine dependence. Overweight and obesity were not related to prevalence of lifetime or past-year illicit drug use disorders in either gender, with no significant interactions.
