Chunk #7 — Structural Magnetic Resonance Imaging

Source

Neuroimaging in alcohol use disorder: From mouse to man.

Embedded

yes

Text

thalamus, cerebellum (vermis, dentate nuclei), pons, medulla, tectal plates, olivary bodies, and midbrain (red nuclei, substantia nigra) (Ha, Weon, Jang, Kang, & Choi, 2012; Kalidass, Sunnathkal, Rangashamanna, & Paraswani, 2012; Kang, Kang, Choi, & Choi, 2005; Liou, Kuo, & Chen, 2012; Murata et al., 2001; Nishida, Sato, Kobayashi, Morimoto, & Hamaoka, 2009). MRI imaging of the more severe KS reveals substantial volume shrinkage of the mammillary bodies (Sullivan et al., 1999), hippocampus (Sullivan et al., 2003), thalamus, orbitofrontal cortices (Jernigan et al., 1991), cerebellum, and pons (Figure 1B) (Zahr et al., 2009). Together these studies in WE/KS demonstrate dramatic morphological changes particularly targeting limbic and frontocerebellar circuitry.