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Chunk #9 — Materials and methods — Verbal and visuospatial memory components

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Linking DMN connectivity to episodic memory capacity: what can we learn from patients with medial temporal lobe damage?
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reproduced over five learning trials on the Rey Visual Design Learning Test (Spreen and Strauss, 1991) and the total number of trials to reach the learning criteria from the Spatial Conditional Associative Learning task (Petrides, 1985; Taylor et al., 1990). IQ measures included the Verbal and Performance IQ from the Wechsler Abbreviated Scale of Intelligence (Wechsler, 1999). PCA on the z-transformed test scores revealed three latent components that reflected a) verbal memory, b) visuospatial memory, and c) IQ. For the current study, individual test scores were z-transformed to the original 56 patients' distribution and PCA scores were calculated for each component by summing the product of each test's z-score and its corresponding coefficient. As expected, we found a material specific deficit in these patients, i.e., patients with left mTLE in comparison to patients with right mTLE had lower PCA scores on the verbal memory component (t = 2.4, df = 62, p = 0.01) but higher PCA components on the visuospatial memory component (t = 1.9, df = 62, p = 0.03). In line with the view that the MTL is less pivotal for intelligence, the full scale Wechsler IQ of the patients fell well within the healthy range of