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Chunk #1 — Background

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StAR: a simple tool for the statistical comparison of ROC curves.
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Classification tasks in bioinformatics are also common and can be found in many different and relevant applications, such as the prediction of genome and protein structure [2,3], the prediction of the cellular location [4], the prediction of molecular function [5] and the prediction of molecular interactions [6]. In general, a classification process is always involved in the prediction of a pattern that can be related to some response in living systems.