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Chunk #15 — Methods — Randomization and statistical analysis

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Racial differences in smoking abstinence rates in a multicenter, randomized, open-label trial in the United States.
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The primary endpoint of this study was the week 12, 7-day point-prevalence, biochemically confirmed, smoking abstinence rate. These cessation rates were tested using two-sided chi-squared tests. With about 172 minorities and over 1,500 whites, this study had 80% power to detect a clinically significant 10% point difference in smoking abstinence rates between the two groups (assuming a baseline success rate of 25% for each of the treatments).