We compiled six disease- and tissue-specific gene expression datasets consisting of 1647 postmortem specimens from three brain regions (PCF (BA9), VC (BA17) and CB) in LOAD and non-demented subjects recruited through the Harvard Brain Tissue Resource Center (HBTRC). Each subject was diagnosed at intake and via extensive neuropathology examination. Tissues were profiled on a custom-made Agilent 44K array of 40,638 DNA probes and each subject genotyped for 838,958 SNPs.
