The results from this family GWAS have provided the first genome-wide significant association of theta oscillations with three SNPs in KCNJ6. These SNPs were associated with theta oscillations across the scalp; however, the strongest associations were frontal (Fz). One imputed synonymous SNP in exon four, highly correlated with our top three SNPs, was significantly associated with the frontal theta ERO phenotype. These results suggest a role for KCNJ6 or its product GIRK2 in variations of frontal theta band oscillations.
