Genotype and allele frequencies of 1194 SNPs from 130 candidate genes (Hodgkinson et al., 2008) were analyzed for association with heroin addiction in 369 AA samples (202 cases and 167 controls). One hundred fifty six SNPs were excluded from analysis because of inadequate quality (cluster separation score < 0.4), low variability (MAF < 0.01) (Table S1), or deviation from Hardy-Weinberg equilibrium in the control sample. Genotyping reproducibility was 99.9% and the mean marker call rate after exclusion was 99.8%.
