Finally, we tested for sex differences in the interaction between relationship status and GPS. We found no evidence of a significant three-way interaction between sex, relationship status and GPS for either drinking frequency or AD symptoms. However, we did find a significant three-way interaction in the models for intoxication frequency. This interaction remained significant even after adjusting for possible confounding in the G × E interactions. Figure 3 displays the predicted values from this model. For intoxication frequency, the G × E effect appears to be driven by the effect in males.
