The study also has limitations. There are relatively few racial and ethnic minorities, which limits the ability to examine associations across race and ethnicity. However, clinical data collection procedures are similar in many respects to the Minority Aging Research Study whic allows data to be merged to examine potential racial differences [80, 102, 124, 125, 136, 237]. In addition, this is a volunteer cohort that has agreed to autopsy at study entry. Thus, participants may not be representative of the general population of older persons and similar types of studies will need to be done in cohorts with a greater proportion of racial and ethnic minorities, and in population based cohorts.
