Several studies in the field of adolescent addiction fMRI have evaluated working memory. This area has been a target because the neural structures and functions that underlie working memory continue to develop during adolescence (Crone, Wendelken, Donohue, van Leijenhorst, & Bunge, 2006). In adults, this network includes the premotor cortex, dorsolateral PFC (dlPFC), ventrolateral PFC (vlPFC), frontal poles, inferior and posterior parietal cortex and cerebellum (Owen, McMillan, Laird, & Bullmore, 2005). Studies suggest that during adolescence, these activation patterns localize to more posterior- and right-sided areas, with the inferior parietal lobe gaining greater involvement (Spadoni et al., 2013).
