Neuropsychological differences between alcohol-dependent and cocaine-dependent patients with or without problematic drinking.
- Authors
- Easton, C; Bauer, L O
- Year
- 1997
- Journal
- Psychiatry research
- PMID
- 9255854
- DOI
- 10.1016/s0165-1781(97)00052-8
The present study evaluated differences among three groups of substance abusers, abstinent for 1-5 months. One group was composed of 17 alcohol-dependent patients. The other two groups were composed of cocaine-dependent patients who scored below (n = 29) or above (n = 18) the median Michigan Alcoholism Screening Test (MAST) score for the cocaine-dependent group in total. The Shipley Institute of Living Scale was administered to all subjects. An ANOVA, with age as a covariate, revealed that the cocaine-dependent group with lower MAST scores exhibited statistically significant impairments on the Shipley abstraction subtest and on total IQ relative to the two other groups. There were no group differences on the verbal subtest. The abstraction and IQ deficits in the lower MAST score cocaine-dependent group could not be explained by decreased verbal abilities, a greater duration or frequency of cocaine use, or by a higher prevalence of Antisocial Personality Disorder. However, a chi 2 analysis revealed that this group contained more individuals who used cocaine in its 'freebase' or smoked form. Since the two cocaine-dependent groups were comparable in demographic and psychological characteristics, but had different levels of cocaine exposure, the results suggest that the decrements in abstraction scores reflect a cocaine-related effect.
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External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| A preliminary investigation of Stroop-related intrinsic connectivity in cocaine dependence: associations with treatment outcomes. | Mitchell MR et al. | — | 2013 | → |
| Executive control deficits in substance-dependent individuals: a comparison of alcohol, cocaine, and methamphetamine and of men and women. | van der Plas EA et al. | — | 2009 | → |
| Impaired reproduction of three-dimensional objects by cocaine-dependent subjects. | Elman I et al. | — | 2008 | → |
| N400 as an index of semantic expectancies: differential effects of alcohol and cocaine dependence. | Ceballos NA et al. | — | 2005 | → |
| Cingulate hypoactivity in cocaine users during a GO-NOGO task as revealed by event-related functional magnetic resonance imaging. | Kaufman JN et al. | — | 2003 | → |
| Cognitive efficiency in stimulant abusers with and without alcohol dependence. | Lawton-Craddock A et al. | — | 2003 | → |
| Effects of concurrent use of alcohol and cocaine. | Pennings EJ et al. | — | 2002 | → |
| Neuropsychological performance of individuals dependent on crack-cocaine, or crack-cocaine and alcohol, at 6 weeks and 6 months of abstinence. | Di Sclafani V et al. | — | 2002 | → |
| Antisocial personality disorder and cocaine dependence: their effects on behavioral and electroencephalographic measures of time estimation. | Bauer LO | — | 2001 | → |
| CNS recovery from cocaine, cocaine and alcohol, or opioid dependence: a P300 study. | Bauer LO | — | 2001 | → |
| Subject-collateral reports of drinking in inpatient alcoholics with comorbid cocaine dependence. | Stasiewicz PR et al. | — | 1999 | → |
| Quantitative electroencephalographic differences associated with alcohol, cocaine, heroin and dual-substance dependence. | Costa L et al. | — | 1997 | → |