Personalized medicine in psychiatry.
- Authors
- Wium-Andersen, Ida Kim; Vinberg, Maj; Kessing, Lars Vedel; McIntyre, Roger S
- Year
- 2017
- Journal
- Nordic journal of psychiatry
- PMID
- 27564242
- DOI
- 10.1080/08039488.2016.1216163
BACKGROUND: Personalized medicine is a model in which a patient's unique clinical, genetic, and environmental characteristics are the basis for treatment and prevention. Aim, method, and results: This review aims to describe the current tools, phenomenological features, clinical risk factors, and biomarkers used to provide personalized medicine. Furthermore, this study describes the target areas in which they can be applied including diagnostics, treatment selection and response, assessment of risk of side-effects, and prevention. DISCUSSION AND CONCLUSION: Personalized medicine in psychiatry is challenged by the current taxonomy, where the diagnostic categories are broad and great biological heterogeneity exists within each category. There is, thus, a gap between the current advanced research prospects and clinical practice, and the current taxonomy is, thus, a poor basis for biological research. The discussion proposes possible solutions to narrow this gap and to move psychiatric research forward towards personalized medicine.
No figures extracted from this document.
No chunks โ full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | 2018 | 29227573 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Considerations for informing precision psychiatry in eating disorders: Foundations for future practice. | Obeid N et al. | โ | 2025 | โ |
| Evaluating the Real-World Pharmacokinetics of Risperidone ISM<sup>ยฎ</sup> in Routine Clinical Practice. | Toja-Camba FJ et al. | โ | 2025 | โ |
| Machine learning approaches in the therapeutic outcome prediction in major depressive disorder: a systematic review. | Ntam VA et al. | โ | 2025 | โ |
| Treating the individual: moving towards personalised eating disorder care. | Bryant E et al. | โ | 2025 | โ |
| Challenges and Opportunities in Managing Geriatric Depression: The Role of Personalized Medicine and Age-Appropriate Therapeutic Approaches. | Jaros A et al. | โ | 2024 | โ |
| Circadian markers as a predictor of response in the treatment of depression-A systematic review. | Druiven SJM et al. | โ | 2024 | โ |
| Personalised medicine: a healing application within comorbid PTSD and mTBI military patient sample with a particular focus on special operators. | Moret NE et al. | โ | 2024 | โ |
| Personalized medicine in old age psychiatry and Alzheimer's disease. | Siafarikas N | โ | 2024 | โ |
| The transition towards community-based mental health care in the European Union: Current realities and prospects. | Vandoni M et al. | โ | 2024 | โ |
| Challenges in Identifying Individualized Brain Biomarkers of Late Life Depression. | Hannon K et al. | โ | 2023 | โ |
| Early indicators of response to transdiagnostic treatment of pediatric anxiety and depression. | Goger P et al. | โ | 2023 | โ |
| Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial - CADOT. | Dormegny-Jeanjean LC et al. | โ | 2023 | โ |
| The longitudinal trajectory of emotional cognition in subgroups of recently diagnosed patients with bipolar disorder. | de Siqueira Rotenberg L et al. | โ | 2023 | โ |
| Computational Models in Electroencephalography. | Glomb K et al. | โ | 2022 | โ |
| Hair cortisol change at COVID-19 pandemic onset predicts burnout among health personnel. | Marcil MJ et al. | โ | 2022 | โ |
| Psychosocial Profiles of Patients Admitted to Psychiatric Emergency Services: Results from the Signature Biobank Project. | Geoffrion S et al. | โ | 2022 | โ |
| Toward Precision Medicine in ADHD. | Buitelaar J et al. | โ | 2022 | โ |
| Vulnerability factors and neuropsychiatric disorders: What could be learned from individual variability in cognitive functions. | Daprati E et al. | โ | 2022 | โ |
| Convergence between clinician-rated and patient-reported PTSD symptoms in a specialized outpatient service: The moderator role of gender. | Ferretti F et al. | โ | 2021 | โ |
| Integrating Psychiatry and Medical Biotechnology as a Way to Achieve Scientific, Precision, and Personalized Psychiatry. | Shamabadi A et al. | โ | 2021 | โ |
| Machine learning approaches for parsing comorbidity/heterogeneity in antisociality and substance use disorders: A primer. | Shane MS et al. | โ | 2021 | โ |
| Oxidative Stress Biomarkers as a Predictor of Stage Illness and Clinical Course of Schizophrenia. | Juchnowicz D et al. | โ | 2021 | โ |
| Personalized Healthcare: The Importance of Patients' Rights in Clinical Practice from the Perspective of Nursing Students in Poland, Spain and Slovakia-A Cross-Sectional Study. | Kupcewicz E et al. | โ | 2021 | โ |
| Predominant Polarity and Polarity Index of Maintenance Treatments for Bipolar Disorder: A Validation Study in a Large Naturalistic Sample in Italy. | Albert U et al. | โ | 2021 | โ |
| Assessment of Population Well-Being With the Mental Health Quotient (MHQ): Development and Usability Study. | Newson JJ et al. | โ | 2020 | โ |
| Can personalized treatment prediction improve the outcomes, compared with the group average approach, in a randomized trial? Developing and validating a multivariable prediction model in a pragmatic megatrial of acute treatment for major depression. | Furukawa TA et al. | โ | 2020 | โ |
| Current challenges and possible future developments in personalized psychiatry with an emphasis on psychotic disorders. | Levchenko A et al. | โ | 2020 | โ |
| Exploring Health Literacy in Individuals with Alcohol Addiction: A Mixed Methods Clinical Study. | Rolova G et al. | โ | 2020 | โ |
| Four Actionable Bottlenecks and Potential Solutions to Translating Psychiatric Genetics Research: An Expert Review. | Bourdon JL et al. | โ | 2020 | โ |
| Pharmacological strategies for the management of comorbid depression and schizophrenia. | Ceskova E | โ | 2020 | โ |
| The Discovery of Clinically Applicable Biomarkers for Bipolar Disorder: A Review of Candidate and Proteomic Approaches. | Muneer A | โ | 2020 | โ |
| The Empathic Brain of Psychopaths: From Social Science to Neuroscience in Empathy. | van Dongen JDM | โ | 2020 | โ |
| Toward prevention of bipolar disorder in at-risk children: Potential strategies ahead of the data. | Post RM et al. | โ | 2020 | โ |
| Analysis of Lithuanian CYP2D6 polymorphism and its relevance to psychiatric care of the local population. | Dlugauskas E et al. | โ | 2019 | โ |
| The Finnish psychiatric birth cohort consortium (PSYCOHORTS) - content, plans and perspectives. | Filatova S et al. | โ | 2019 | โ |
| Bifrontal active and sham rTMS in treatment-resistant unipolar major depression. | Valkonen-Korhonen M et al. | โ | 2018 | โ |
| Can an Integrated Science Approach to Precision Medicine Research Improve Lithium Treatment in Bipolar Disorders? | Scott J et al. | โ | 2018 | โ |
| Does S100B have a potential role in affective disorders? A literature review. | Kroksmark H et al. | โ | 2018 | โ |
| Objective and quantitative equilibriometric evaluation of individual locomotor behaviour in schizophrenia: Translational and clinical implications. | Haralanov S et al. | โ | 2018 | โ |
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | Dick DM et al. | โ | 2018 | โ |
| Precision pharmacotherapy: psychiatry's future direction in preventing, diagnosing, and treating mental disorders. | Menke A | โ | 2018 | โ |
| Precision Psychiatry and Dual Disorders. | Szerman N et al. | โ | 2018 | โ |
| The functional variant rs334558 of <i>GSK3B</i> is associated with remission in patients with depressive disorders. | Levchenko A et al. | โ | 2018 | โ |
| Association analysis of ANK3 variants with bipolar disorder in the Korean population. | Cho CH et al. | โ | 2017 | โ |