Predictors of the 2-year recurrence and persistence of alcohol dependence.
- Authors
- Boschloo, Lynn; Vogelzangs, Nicole; van den Brink, Wim; Smit, Johannes H; Beekman, Aartjan T F; Penninx, Brenda W J H
- Year
- 2012
- Journal
- Addiction (Abingdon, England)
- PMID
- 22372473
- DOI
- 10.1111/j.1360-0443.2012.03860.x
AIMS: To identify independent risk factors of the recurrence of alcohol dependence (AD) in people with a remitted disorder at baseline and persistence of AD in people with a current disorder at baseline. DESIGN: Prospective cohort study with assessments at baseline and 2-year follow-up. SETTING: Recruitment from the general population, primary care and out-patient mental health-care services. PARTICIPANTS: People with remitted AD (n = 253) and current AD (n = 135). MEASUREMENTS: Recurrence and persistence of AD during 2-year follow-up were established using the Composite International Diagnostic Interview (CIDI) interview based on DSM-IV. Logistic regression analyses were performed to explore the role of potential risk factors (i.e. baseline severity of alcohol problems, measures for depression and anxiety, socio-demographics, vulnerability factors and addiction-related factors) as independent predictors of a negative course. FINDINGS: Overall recurrence and persistence rates of AD were 14.6 and 40.7%, respectively, and were highly conditional on the severity of alcohol problems [adjusted odds ratio (OR) per standard deviation (SD) increase: OR = 3.64, 95% confidence interval (CI): 2.21-6.01 and OR = 2.12, 95% CI: 1.32-3.40, respectively). Severity of depressive/anxiety symptoms was an additional independent predictor of the recurrence of AD, whereas male gender and high education were significant independent risk factors of the persistence of AD. CONCLUSIONS: Alcohol dependence has a dynamic course, with only moderate levels of diagnostic stability. Both recurrence and persistence of alcohol dependence are highly dependent on severity of baseline alcohol problems, whereas severity of depressive/anxiety symptoms predicts only the recurrence of alcohol dependence. Both measures may be useful in identifying people at an increased risk of a negative course and who could be targeted by prevention strategies.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Normative Values and Psychometric Properties of the Penn State Worry Questionnaire in Substance Use Disorder Treatment Population. | Hochheimer M et al. | β | 2026 | β |
| Sociodemographic risk factors for the persistence of harmful alcohol use: a pooled analysis of prospective cohort studies. | Ehrnrooth A et al. | β | 2025 | β |
| Atypical effective connectivity from the frontal cortex to striatum in alcohol use disorder. | Song H et al. | β | 2024 | β |
| The effects and challenges of alcohol use disorder peer support service in South Korea: A focus group study. | Kim S et al. | β | 2024 | β |
| Deconstructing the heterogeneity of alcohol use disorder: lifetime comorbid non-alcohol substance use disorder as a distinct behavioral phenotype? | Farmer RF et al. | β | 2023 | β |
| Childhood Trauma and Dissociation Correlates in Alcohol Use Disorder: A Cross-Sectional Study in a Sample of 587 French Subjects Hospitalized in a Rehabilitation Center. | Baudin G et al. | β | 2022 | β |
| Diagnostic remission of substance use disorders: Racial differences and correlates of remission in a nationally representative sample. | Bommersbach TJ et al. | β | 2022 | β |
| Family-Based Predictors of Alcohol Use Disorder (AUD) Recurrence and New Non-Alcohol Substance Use Disorder Onset Following Initial AUD Recovery. | Farmer RF et al. | β | 2022 | β |
| Predictors of early and sustained cessation of heavy drinking over 5Β years among adult primary care patients. | Palzes VA et al. | β | 2022 | β |
| Repetitive transcranial magnetic stimulation combined with cognitive behavioral therapy treatment in alcohol-dependent patients: A randomized, double-blind sham-controlled multicenter clinical trial. | Hu X et al. | β | 2022 | β |
| Alcohol dependence severity determines the course of treatment-seeking patients. | Yoshimura A et al. | β | 2021 | β |
| Delta resting-state functional connectivity in the cognitive control network as a prognostic factor for maintaining abstinence: An eLORETA preliminary study. | Januszko P et al. | β | 2021 | β |
| Impulsivity Scale-12 and its utilization in alcohol use disorder. | SzczypiΕski J et al. | β | 2021 | β |
| Alcohol use in adolescents and adult psychopathology and social outcomes: Findings from a 35-year cohort study. | Boden J et al. | β | 2020 | β |
| Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model. | Rautiainen E et al. | β | 2020 | β |
| Traumatic experiences, mental health, social support and demographics as correlates of alcohol dependence in a sample of Lithuanian police officers. | ArgustaitΔ-ZailskienΔ G et al. | β | 2020 | β |
| Alcohol use disorder relapse factors: A systematic review. | Sliedrecht W et al. | β | 2019 | β |
| A real-world study on clinical predictors of relapse after hospitalized detoxification in a Chinese cohort with alcohol dependence. | Tao YJ et al. | β | 2019 | β |
| Body mass index and craving predict 24-month hospital readmissions of alcohol-dependent in-patients following withdrawal. | Weinland C et al. | β | 2019 | β |
| Prevalence and Correlates of Past-Year Recovery From DSM-5 Alcohol Use Disorder: Results From National Epidemiologic Survey on Alcohol and Related Conditions-III. | Fan AZ et al. | β | 2019 | β |
| Prevalence, incidence, recovery, and recurrence of alcohol use disorders from childhood to age 30. | Seeley JR et al. | β | 2019 | β |
| Aspects of alcohol use disorder affecting social cognition as assessed using the Mini Social and Emotional Assessment (mini-SEA). | Cox S et al. | β | 2018 | β |
| Clinical features associated with an increased risk for alcohol use disorders among family members. | Farmer RF et al. | β | 2018 | β |
| Codevelopment Between Key Personality Traits and Alcohol Use Disorder From Adolescence Through Young Adulthood. | Samek DR et al. | β | 2018 | β |
| Self-guided Change: The most common form of long-term, maintained health behavior change. | Bishop FM | β | 2018 | β |
| Cloninger Type 2 Score and Lesch Typology Predict Hospital Readmission of Female and Male Alcohol-Dependent Inpatients During a 24-Month Follow-Up. | Weinland C et al. | β | 2017 | β |
| Confidentiality and the Role of the Addiction Specialist Team in Liver Transplantation Procedures. Commentary on Donnadieu-Rigole etΒ al., 2017, Follow-Up of Alcohol Consumption After Liver Transplantation: Interest of an Addiction Team? | Dom G | β | 2017 | β |
| Differences Between Treatment-Seeking and Nontreatment-Seeking Alcohol-Dependent Research Participants: An Exploratory Analysis. | Rohn MC et al. | β | 2017 | β |
| Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands. | McCutcheon VV et al. | β | 2017 | β |
| Gender and race/ethnic differences in the persistence of alcohol, drug, and poly-substance use disorders. | Evans EA et al. | β | 2017 | β |
| Predictors of Persistence of Risky Drinking in Adults: An 11-Year Follow-Up Study. | HΓ€rkΓΆnen J et al. | β | 2017 | β |
| Risk for alcoholic liver cirrhosis after an initial hospital contact with alcohol problems: A nationwide prospective cohort study. | Askgaard G et al. | β | 2017 | β |
| Phenobarbital compared to benzodiazepines in alcohol withdrawal treatment: A register-based cohort study of subsequent benzodiazepine use, alcohol recidivism and mortality. | Askgaard G et al. | β | 2016 | β |
| Predictors of heavy drinking after liver transplantation for alcoholic liver disease in Denmark (1990-2013): a nationwide study with competing risks analyses. | Askgaard G et al. | β | 2016 | β |
| Reductions in physical pain predict lower risk of relapse following alcohol treatment. | Jakubczyk A et al. | β | 2016 | β |
| The Relationship Between Generalized Anxiety Symptoms and Treatment Dropout Among Women in Residential Treatment for Substance Use Disorders. | Elmquist J et al. | β | 2016 | β |
| Assessing and treating alcohol relapse risk in liver transplantation candidates. | Dom G et al. | β | 2015 | β |
| Co-morbid anxiety disorders predict early relapse after inpatient alcohol treatment. | Schellekens AF et al. | β | 2015 | β |
| Physical Pain in Alcohol-Dependent Patients Entering Treatment in PolandβPrevalence and Correlates. | Jakubczyk A et al. | β | 2015 | β |
| [Comorbidity of affective disorders and alcohol use disorder]. | Pringuey D et al. | β | 2014 | β |
| Does self-medication predict the persistence or rather the recurrence of alcohol dependence?--reply. | Crum RM et al. | β | 2014 | β |
| Efficacy of disulfiram for the treatment of alcohol dependence assessed with a multicenter randomized controlled trial. | Yoshimura A et al. | β | 2014 | β |
| Predictive validity of the AUDIT for hazardous alcohol consumption in recently released prisoners. | Thomas E et al. | β | 2014 | β |
| Predictors of quit attempts and successful quit attempts among individuals with alcohol use disorders in a nationally representative sample. | Chiappetta V et al. | β | 2014 | β |
| The patterns of drug and alcohol use and associated problems over 30 years in 397 men. | Schuckit MA et al. | β | 2014 | β |
| Clinical practice. Alcohol use in adults. | Friedmann PD | β | 2013 | β |
| Patterns of lifetime PTSD comorbidity: a latent class analysis. | Galatzer-Levy IR et al. | β | 2013 | β |
| Predicting persistency of DSM-5 alcohol use disorder and examining drinking patterns of recently remitted individuals: a prospective general population study. | Tuithof M et al. | β | 2013 | β |
| Predictors of initial and sustained remission from alcohol use disorders: findings from the 30-year follow-up of the San Diego Prospective Study. | Trim RS et al. | β | 2013 | β |
| Relationship of reasons and fears of treatment with outcome in substance using population attending a de-addiction centre. | Sarkar S et al. | β | 2013 | β |
| The CC genotype in the T102C HTR2A polymorphism predicts relapse in individuals after alcohol treatment. | Jakubczyk A et al. | β | 2013 | β |
| The effects of venlafaxine and cognitive behavioral therapy alone and combined in the treatment of co-morbid alcohol use-anxiety disorders. | Ciraulo DA et al. | β | 2013 | β |