Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes.
paper
Cited
Public
Unavailable
- Authors
- Sinha, Rajita; Garcia, Miguel; Paliwal, Prashni; Kreek, Mary Jeanne; Rounsaville, Bruce J
- Year
- 2006
- Journal
- Archives of general psychiatry
- PMID
- 16520439
- DOI
- 10.1001/archpsyc.63.3.324
BACKGROUND: Cocaine dependence is associated with high rates of relapse. Stress and drug cue exposure are known to increase cocaine craving and stress arousal, but the association between these responses and cocaine relapse has not been previously studied. OBJECTIVE: To examine whether stress-induced and drug cue-induced cocaine craving and hypothalamic-pituitary-adrenal axis responses evoked in the laboratory are associated with subsequent cocaine relapse. DESIGN: Prospective study design assessing cocaine relapse and drug use during a 90-day follow-up period after discharge from inpatient treatment and research. Data were analyzed by Cox proportional hazards regression and multiple regression. SETTING: Inpatient treatment and research unit in a community mental health center. PATIENTS: Forty-nine treatment-seeking cocaine-dependent individuals. MAIN OUTCOME MEASURES: Time to cocaine relapse, number of days of cocaine use, and amount of cocaine used per occasion in the follow-up phase. RESULTS: Greater stress-induced, but not drug cue-induced, cocaine craving was associated with a shorter time to cocaine relapse. Stress-induced corticotropin and cortisol responses predicted higher amounts of cocaine use per occasion in the 90-day follow-up. CONCLUSIONS: These results demonstrate that stress-related increases in cocaine craving and hypothalamic-pituitary-adrenal axis responses are each associated with specific cocaine relapse outcomes. The findings support the use of stress-induced drug craving and associated hypothalamic-pituitary-adrenal axis responses to evaluate cocaine relapse propensity. Furthermore, treatments that address stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses could be of benefit in improving relapse outcomes in cocaine dependence.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Genetic influences on craving for alcohol. | 2013 | 22481050 |
| Consilient research approaches in studying gene x environment interactions in alcohol research. | 2010 | 20148780 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Electrophysiology and Functional Magnetic Resonance Imaging of Cue Craving: Potential Biomarkers for Therapeutic Neuromodulation in Addiction. | Tanabe J et al. | β | 2026 | β |
| Excessive Overdoses Where Treatment Centers Are Concentrated: A Case Study of Orange County, California. | Shrira I et al. | β | 2026 | β |
| Aversion-induced dopamine reductions predict drug-taking and escape behaviors. | Grafelman EM et al. | β | 2025 | β |
| Biochemical Diagnosis in Substance and Non-substance Addiction. | Shen W et al. | β | 2025 | β |
| Brain connectomics markers for response prediction to transcranial magnetic stimulation in cocaine use disorder. | Ghazi N et al. | β | 2025 | β |
| Cocaine Cues Used in Experimental Research: A Systematic Review. | Brobbin E et al. | β | 2025 | β |
| Early alcohol abstinence symptoms and the role of cumulative adversity. | Fox HC et al. | β | 2025 | β |
| Fos expression in the periaqueductal gray, but not the ventromedial hypothalamus, is correlated with psychosocial stress-induced cocaine-seeking behavior in rats. | Hinds NM et al. | β | 2025 | β |
| From Stress to Substance Use Disorders: The Expanding Role of Microglia-Astrocyte Crosstalk in Neuroimmune and Glutamate Alterations in the Nucleus Accumbens. | Cancela LM et al. | β | 2025 | β |
| IGF2 modulates behavioral and hippocampal changes induced by chronic cocaine exposure during adolescence in mice. | Gil-RodrΓguez S et al. | β | 2025 | β |
| Laboratory and Real-World Experimental Approaches to Understanding Alcohol Relapse. | Milivojevic V et al. | β | 2025 | β |
| Neurobiological intersections of stress and substance use disorders. | Juliano VAL et al. | β | 2025 | β |
| Optimization of the Macrocyclic Tetrapeptide [D-Trp]CJ-15,208 to Prevent Stress-Induced Relapse of Cocaine-Seeking Behavior. | Aldrich JV et al. | β | 2025 | β |
| Optimizing an App-Based Just-in-Time Adaptive Intervention for Stimulant Use Among Sexual Minority Men Living with HIV: Protocol for a Community-Engaged Research Approach and Hybrid-Experimental Design. | Sizemore KM et al. | β | 2025 | β |
| Paternal Cocaine Exposure and Its Testicular Legacy: Epigenetic, Physiological, and Intergenerational Consequences. | GonzΓ‘lez CR et al. | β | 2025 | β |
| Pregnenolone reduces provoked craving and cocaine use in men and women with cocaine use disorder: A pilot trial. | Sakmar E et al. | β | 2025 | β |
| Sleep disruption, stress, and craving during inpatient treatment for opioid use disorder. | Bichon JA et al. | β | 2025 | β |
| Subtypes of cocaine use disorder and their neurobehavioral profiles. | Brucar LR et al. | β | 2025 | β |
| Aversion-induced drug taking and escape behavior involve similar nucleus accumbens core dopamine signaling signatures | Grafelman EM et al. | β | 2024 | β |
| Effects of behavioral interventions on stress reactivity in adults with substance use disorders. | McHugh RK et al. | β | 2024 | β |
| Evaluation of a digital tool for detecting stress and craving in SUD recovery: An observational trial of accuracy and engagement. | Carreiro S et al. | β | 2024 | β |
| Explaining child maltreatment and aggression among Chinese drug user: The mediating and moderating roles of drug craving and impulsivity. | Lu Z et al. | β | 2024 | β |
| Hair cortisol and substance use among women currently experiencing intimate partner violence: The role of PTSD symptom severity. | Forkus SR et al. | β | 2024 | β |
| Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. | Schick MR et al. | β | 2024 | β |
| Physical Exercise to Redynamize Interoception in Substance use Disorders. | Brevers D et al. | β | 2024 | β |
| Psychological factors predicting patients' risk of relapse after enrollment in drug use treatment: A systematic review. | Del Palacio-Gonzalez A et al. | β | 2024 | β |
| Stress and substance use disorders: risk, relapse, and treatment outcomes. | Sinha R | β | 2024 | β |
| The importance of community engagement in experimental stress and substance use research with marginalized groups: Lessons from research with sexual and gender minority populations. | Fahey KML et al. | β | 2024 | β |
| The Neurocircuitry of Substance Use Disorder, Treatment, and Change: A Resource for Clinical Psychiatrists. | Imperio CG et al. | β | 2024 | β |
| Time perception in stimulant-dependent participants undergoing repetitive transcranial magnetic stimulation. | Cardullo S et al. | β | 2024 | β |
| A Prospective Biopsychosocial Repeated Measures Study of Stress and Dropout from Substance Addiction Treatment. | BΓΈhle K et al. | β | 2023 | β |
| Cocaine use disorder patients develop distinct patterns of regulation of acth secretion by a vasopressin agonist and oxytocin: Report on a laboratory study. | Raby WN et al. | β | 2023 | β |
| Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. | Mews P et al. | β | 2023 | β |
| Craving among patients seeking treatment for substance use disorder. | Cless MM et al. | β | 2023 | β |
| Cross-talk between the HPA axis and addiction-related regions in stressful situations. | Nikbakhtzadeh M et al. | β | 2023 | β |
| Estradiol enhances the mirtazapine effects on the expression of cocaine-induced locomotor sensitization in female rats. | Barbosa-MΓ©ndez S et al. | β | 2023 | β |
| Relapse Prevention and Prediction Strategies in Substance Use Disorder: A Scoping Review. | Carter T et al. | β | 2023 | β |
| Role of mesolimbic cannabinoid receptor 1 in stress-driven increases in cocaine self-administration in male rats. | McReynolds JR et al. | β | 2023 | β |
| Sex differences in neural responses to stress and drug cues predicts future drug use in individuals with substance use disorder. | Smith K et al. | β | 2023 | β |
| Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect. | Towers EB et al. | β | 2023 | β |
| The Craving-Manager smartphone app designed to diagnose substance use/addictive disorders, and manage craving and individual predictors of relapse: a study protocol for a multicenter randomized controlled trial. | Serre F et al. | β | 2023 | β |
| Therapeutics for Substance-Using Women: The Need to Elucidate Sex-Specific Targets for Better-Tailored Treatments. | Fox HC et al. | β | 2023 | β |
| Using ecological momentary assessments of negative affect and craving during residential opioid use disorder treatment to predict patients' relapse to substance use. | Cleveland HH et al. | β | 2023 | β |
| Alterations of Stress-Related Glucocorticoids and Endocannabinoids in Hair of Chronic Cocaine Users. | Voegel CD et al. | β | 2022 | β |
| Applying the Addictions Neuroclinical Assessment to derive neurofunctional domains in individuals who use methamphetamine. | Nieto SJ et al. | β | 2022 | β |
| Cannabidiol Effect on Anxiety Symptoms and Stress Response in Individuals With Cocaine Use Disorder: Exploratory Results From a Randomized Controlled Trial. | Mongeau-PΓ©russe V et al. | β | 2022 | β |
| Corticotropin releasing factor and drug seeking in substance use disorders: Preclinical evidence and translational limitations. | Mantsch JR | β | 2022 | β |
| Craving of prescription opioids among veterans with chronic pain. | Toor T et al. | β | 2022 | β |
| Cue-induced cocaine craving enhances psychosocial stress and vice versa in chronic cocaine users. | Kexel AK et al. | β | 2022 | β |
| Intranasal oxytocin may improve odds of abstinence in cocaine-dependent patients: results from a preliminary study. | NoΓ«l Raby W et al. | β | 2022 | β |
| Is There an Association Between Salivary Cortisol and Dropping Out of Inpatient Substance Addiction Treatments? A Prospective Repeated Measures Study. | BΓΈhle K et al. | β | 2022 | β |
| Learning from addiction: Craving of prescription opioids in chronic pain sufferers. | Strigo IA et al. | β | 2022 | β |
| Predictors of Relapse to Alcohol and Substance Use: Are There Any Differences between 3 and 12 Months after Inpatient Treatment? | Guliyev C et al. | β | 2022 | β |
| Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. | Milivojevic V et al. | β | 2022 | β |
| Repetitive Transcranial Magnetic Stimulation (rTMS) as a Promising Treatment for Craving in Stimulant Drugs and Behavioral Addiction: A Meta-Analysis. | Gay A et al. | β | 2022 | β |
| Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review. | Nicolas C et al. | β | 2022 | β |
| Stress- and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders. | Smiley CE et al. | β | 2022 | β |
| SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress. | Zayed A et al. | β | 2022 | β |
| The Effect of Different Transcranial Direct Current Stimulation (tDCS) Protocols on Drug Craving and Cognitive Functions in Methamphetamine Addicts. | Rezvanian S et al. | β | 2022 | β |
| The endocannabinoid system and drug-associated contextual memories. | Asth L et al. | β | 2022 | β |
| Associations Between Physiological Signals Captured Using Wearable Sensors and Self-reported Outcomes Among Adults in Alcohol Use Disorder Recovery: Development and Usability Study. | Alinia P et al. | β | 2021 | β |
| Consolidating the Circuit Model for Addiction. | LΓΌscher C et al. | β | 2021 | β |
| Depression and substance use disorders: Clinical comorbidity and shared neurobiology. | Calarco CA et al. | β | 2021 | β |
| Effects of cortisol administration on craving during in vivo exposure in patients with alcohol use disorder. | Soravia LM et al. | β | 2021 | β |
| Genetically selected alcohol-preferring msP rats to study alcohol use disorder: Anything lost in translation? | Borruto AM et al. | β | 2021 | β |
| Inhibitory failures in cocaine use disorder: Not paying attention when there is a need to be cautious. | Howlett JR et al. | β | 2021 | β |
| Laboratory-induced stress and craving predict opioid use during follow-up among individuals with prescription opioid use disorder. | Saraiya TC et al. | β | 2021 | β |
| Neurochemical mechanisms and neurocircuitry underlying the contribution of stress to cocaine seeking. | Caccamise A et al. | β | 2021 | β |
| Psychometric properties and longitudinal measurement invariance of the drug craving scale: Modification of the Polish version of the Penn Alcohol Craving Scale (PACS). | Opozda-Suder S et al. | β | 2021 | β |
| Psychosocial Factors Predict the Level of Substance Craving of People with Drug Addiction: A Machine Learning Approach. | Gong H et al. | β | 2021 | β |
| Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction. | Zhang S et al. | β | 2021 | β |
| Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid. | Chou YH et al. | β | 2021 | β |
| Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory. | Hogarth L | β | 2020 | β |
| Behavioral strategies to reduce stress reactivity in opioid use disorder: Study design. | McHugh RK et al. | β | 2020 | β |
| Cue-elicited functional connectivity of the periaqueductal gray and tonic cocaine craving. | Zhang S et al. | β | 2020 | β |
| Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat. | Valenza M et al. | β | 2020 | β |
| Evaluating a longitudinal mediation model of perceived stress, depressive symptoms, and substance use treatment outcomes. | Roos CR et al. | β | 2020 | β |
| Further evidence for the association of <i>GAL</i>, <i>GALR1</i>Β and <i>NPY1R</i>Β variants with opioid dependence. | Randesi M et al. | β | 2020 | β |
| Hypothalamic-pituitary-adrenal axis activity in post-traumatic stress disorder and cocaine use disorder. | Hadad NA et al. | β | 2020 | β |
| Is craving a risk factor for substance use among treatment-seeking individuals with alcohol and other drugs use disorders? A meta-analytic review. | Cavicchioli M et al. | β | 2020 | β |
| Mirtazapine reduces the expression of cocaine-induced locomotor sensitization in male and female Wistar rats. | Barbosa-MΓ©ndez S et al. | β | 2020 | β |
| Neuroendocrine effects of naltrexone versus nalmefene in humans. | Butelman ER et al. | β | 2020 | β |
| Potions for Emotions: Do self-reported individual differences in negative-emotional drinking predict alcohol consumption in the laboratory following exposure to a negative experience? | Austin HRT et al. | β | 2020 | β |
| Program Development of Integrated Psychological Services for Hospitalized Patients with Intravenous Drug Use Histories. | Gill AD et al. | β | 2020 | β |
| Salivary Cortisol Levels Are Associated with Craving and Cognitive Performance in Cocaine-Abstinent Subjects: A Pilot Study. | Sampedro-Piquero P et al. | β | 2020 | β |
| Sex differences in the glutamate system: Implications for addiction. | Giacometti LL et al. | β | 2020 | β |
| Stress Allostasis in Substance Use Disorders: Promise, Progress, and Emerging Priorities in Clinical Research. | Fronk GE et al. | β | 2020 | β |
| The effect of oxytocin, gender, and ovarian hormones on stress reactivity in individuals with cocaine use disorder. | Sherman BJ et al. | β | 2020 | β |
| The neural interface between negative emotion regulation and motivation for change in cocaine dependent individuals under treatment. | Contreras-RodrΓguez O et al. | β | 2020 | β |
| The relationship between perceived stress and depression in substance use disorder treatment. | McHugh RK et al. | β | 2020 | β |
| A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment. | Wemm SE et al. | β | 2019 | β |
| Affective vulnerability in substance use disorders. | McHugh RK et al. | β | 2019 | β |
| Associations among interpretation bias, craving, and abstinence self-efficacy in adults with substance use disorders. | Beard C et al. | β | 2019 | β |
| Brain activity associated with social exclusion overlaps with drug-related frontal-striatal circuitry in cocaine users: A pilot study. | Hanlon CA et al. | β | 2019 | β |
| Drug-induced stress responses and addiction risk and relapse. | Wemm SE et al. | β | 2019 | β |
| Effectiveness of an Integrated Intervention Program for Alcoholism (IIPA) for enhancing self-regulation: Preliminary evidence. | Kumar R et al. | β | 2019 | β |
| Effects of opioids on the parental brain in health and disease. | Swain JE et al. | β | 2019 | β |
| Food craving, cortisol and ghrelin responses in modeling highly palatable snack intake in the laboratory. | Sinha R et al. | β | 2019 | β |
| Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation With Self-Medication Coping Motives and Subjective Reactivity. | Hogarth L et al. | β | 2019 | β |
| Parenting stress: A novel mechanism of addiction vulnerability. | Rutherford HJ et al. | β | 2019 | β |
| Pituitary Adenylate Cyclase-Activating Peptide (PACAP) Signaling and the Dark Side of Addiction. | Miles OW et al. | β | 2019 | β |
| Preliminary development of a neuroimaging paradigm to examine neural correlates of relationship conflict. | Flanagan JC et al. | β | 2019 | β |
| Social stress-potentiated methamphetamine seeking. | Blouin AM et al. | β | 2019 | β |
| Substance use outcomes in cocaine-dependent tobacco smokers: A mediation analysis exploring the role of sleep disturbance, craving, anxiety, and depression. | Winhusen TM et al. | β | 2019 | β |
| Systematic review of the effects of acute stress in binge eating disorder. | Naish KR et al. | β | 2019 | β |
| The Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Emotion Processing, Reappraisal, and Craving in Alcohol Use Disorder Patients and Healthy Controls: A Functional Magnetic Resonance Imaging Study. | Jansen JM et al. | β | 2019 | β |
| 21st century neurobehavioral theories of decision making in addiction: Review and evaluation. | Bickel WK et al. | β | 2018 | β |
| A Neuronal Ensemble in the Rostral Agranular Insula Tracks Cocaine-Induced Devaluation of Natural Reward and Predicts Cocaine Seeking. | Moschak TM et al. | β | 2018 | β |
| Assessing the validity and reliability of the Turkish versions of craving beliefs and beliefs about substance use questionnaire in patients with heroin use disorder: demonstrating valid tools to assess cognition-emotion interplay. | KüçükkarapΔ±nar M et al. | β | 2018 | β |
| Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder. | Preston KL et al. | β | 2018 | β |
| Central and Peripheral Biomarkers of Stress Response for Addiction Risk and Relapse Vulnerability. | Milivojevic V et al. | β | 2018 | β |
| Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference. | Robison LS et al. | β | 2018 | β |
| Depressive statements prime goal-directed alcohol-seeking in individuals who report drinking to cope with negative affect. | Hogarth L et al. | β | 2018 | β |
| End-of-day reports of daily hassles and stress in men and women with opioid-use disorder: Relationship to momentary reports of opioid and cocaine use and stress. | Preston KL et al. | β | 2018 | β |
| Exacerbated Craving in the Presence of Stress and Drug Cues in Drug-Dependent Patients. | Preston KL et al. | β | 2018 | β |
| Modulation of Drug Craving in Crystalline-Heroin Users by Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex. | Sharifi-Fardshad M et al. | β | 2018 | β |
| Pituitary Adenylate Cyclase-Activating Peptide in the Bed Nucleus of the Stria Terminalis Mediates Stress-Induced Reinstatement of Cocaine Seeking in Rats. | Miles OW et al. | β | 2018 | β |
| Risperidone versus other antipsychotics for people with severe mental illness and co-occurring substance misuse. | Temmingh HS et al. | β | 2018 | β |
| Sexual dimorphism in the neural impact of stress and alcohol. | Logrip ML et al. | β | 2018 | β |
| Social defeat stress and escalation of cocaine and alcohol consumption: Focus on CRF. | Newman EL et al. | β | 2018 | β |
| Stress responding in cannabis smokers as a function of trauma exposure, sex, and relapse in the human laboratory. | Chao T et al. | β | 2018 | β |
| Substance use outcomes for mindfulness based relapse prevention are partially mediated by reductions in stress: Results from a randomized trial. | Davis JP et al. | β | 2018 | β |
| Transcranial magnetic stimulation for the treatment of cocaine addiction: evidence to date. | Bolloni C et al. | β | 2018 | β |
| What does the Fos say? Using Fos-based approaches to understand the contribution of stress to substance use disorders. | McReynolds JR et al. | β | 2018 | β |
| Binge-pattern cocaine administration causes long-lasting behavioral hyperarousal but does not enhance vulnerability to single prolonged stress in rats. | Lisieski MJ et al. | β | 2017 | β |
| Biochemical Diagnosis in Substance and Non-substance Addiction. | Shen W et al. | β | 2017 | β |
| Context and craving during stressful events in the daily lives of drug-dependent patients. | Preston KL et al. | β | 2017 | β |
| Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3. | McReynolds JR et al. | β | 2017 | β |
| Current major depression is associated with greater sensitivity to the motivational effect of both negative mood induction and abstinence on tobacco-seeking behavior. | Hogarth L et al. | β | 2017 | β |
| Development of an integrated cognitive behavioral therapy for anxiety and opioid use disorder: Study protocol and methods. | McHugh RK et al. | β | 2017 | β |
| Effect of Door-Locking Policy on Inpatient Treatment of Substance Use and Dual Disorders. | Steinauer R et al. | β | 2017 | β |
| "Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats". | Valenza M et al. | β | 2017 | β |
| Exercise as an Adjunctive Treatment for Substance Use Disorders: Rationale and Intervention Description. | Weinstock J et al. | β | 2017 | β |
| Impact of gender on corticotropin-releasing factor and noradrenergic sensitivity in cocaine use disorder. | McRae-Clark AL et al. | β | 2017 | β |
| Increased startle potentiation to unpredictable stressors in alcohol dependence: Possible stress neuroadaptation in humans. | Moberg CA et al. | β | 2017 | β |
| N-acetylcysteine in the treatment of craving in substance use disorders: Systematic review and meta-analysis. | Duailibi MS et al. | β | 2017 | β |
| Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments. | Kober H et al. | β | 2017 | β |
| Opposing Roles of Rapid Dopamine SignalingΒ Across the Rostral-Caudal Axis ofΒ theΒ Nucleus Accumbens Shell in Drug-Induced Negative Affect. | Hurley SW et al. | β | 2017 | β |
| Probing for Neuroadaptations to Unpredictable Stressors in Addiction: Translational Methods and Emerging Evidence. | Kaye JT et al. | β | 2017 | β |
| Sex differences, gender and addiction. | Becker JB et al. | β | 2017 | β |
| Sex differences in guanfacine effects on stress-induced stroop performance in cocaine dependence. | Milivojevic V et al. | β | 2017 | β |
| The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder. | Castilla-Ortega E et al. | β | 2017 | β |
| A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats. | Manvich DF et al. | β | 2016 | β |
| Biomarkers for Success: Using Neuroimaging to Predict Relapse and Develop Brain Stimulation Treatments for Cocaine-Dependent Individuals. | Hanlon CA et al. | β | 2016 | β |
| Cognitive Function as a Transdiagnostic Treatment Target in Stimulant Use Disorders. | Sofuoglu M et al. | β | 2016 | β |
| Effect of the CRF<sub>1</sub>-receptor antagonist pexacerfont on stress-induced eating and food craving. | Epstein DH et al. | β | 2016 | β |
| Effects of progesterone stimulated allopregnanolone on craving and stress response in cocaine dependent men and women. | Milivojevic V et al. | β | 2016 | β |
| Examining an underlying mechanism between perceived stress and smoking cessation-related outcomes. | Robles Z et al. | β | 2016 | β |
| Examining Risk for Frequent Cocaine Use: Focus on an African American Treatment Population. | Zapolski TC et al. | β | 2016 | β |
| Functional consequences of cocaine expectation: findings in a non-human primate model of cocaine self-administration. | Porrino LJ et al. | β | 2016 | β |
| GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study. | Zois E et al. | β | 2016 | β |
| HPA Axis Interactions with Behavioral Systems. | Packard AE et al. | β | 2016 | β |
| Neuroscience of opiates for addiction medicine: From stress-responsive systems to behavior. | Zhou Y et al. | β | 2016 | β |
| Role of dopamine neurotransmission in the long-term effects of repeated social defeat on the conditioned rewarding effects of cocaine. | Montagud-Romero S et al. | β | 2016 | β |
| Sex Differences in the Association Between Internalizing Symptoms and Craving in Methamphetamine Users. | Hartwell EE et al. | β | 2016 | β |
| Shared and unique mechanisms underlying binge eating disorder and addictive disorders. | Schulte EM et al. | β | 2016 | β |
| Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress. | Mantsch JR et al. | β | 2016 | β |
| The influence of negative urgency, attentional bias, and emotional dimensions on palatable food consumption. | Becker KD et al. | β | 2016 | β |
| The Macronutrients, Appetite, and Energy Intake. | Carreiro AL et al. | β | 2016 | β |
| Biased Perception of Mean Emotion in Abstinent Heroin Abusers. | Zhang M et al. | β | 2015 | β |
| Cocaine potentiates multiple 5-HT2A receptor signaling pathways and is associated with decreased phosphorylation of 5-HT2A receptors in vivo. | Franklin JM et al. | β | 2015 | β |
| Craving and substance use among patients with alcohol, tobacco, cannabis or heroin addiction: a comparison of substance- and person-specific cues. | Fatseas M et al. | β | 2015 | β |
| Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage. | Hurd YL et al. | β | 2015 | β |
| Ecological momentary assessment in the investigation of craving and substance use in daily life: a systematic review. | Serre F et al. | β | 2015 | β |
| Effects of adverse childhood experiences on the association between intranasal oxytocin and social stress reactivity among individuals with cocaine dependence. | Flanagan JC et al. | β | 2015 | β |
| Effects of childhood maltreatment on the neural correlates of stress- and drug cue-induced cocaine craving. | Elton A et al. | β | 2015 | β |
| Growth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target | Wellman M et al. | β | 2015 | β |
| Inoculation stress hypothesis of environmental enrichment. | Crofton EJ et al. | β | 2015 | β |
| Modafinil in the treatment of crack-cocaine dependence in the Netherlands: Results of an open-label randomised controlled feasibility trial. | Nuijten M et al. | β | 2015 | β |
| Noninvasive brain stimulation to suppress craving in substance use disorders: Review of human evidence and methodological considerations for future work. | Hone-Blanchet A et al. | β | 2015 | β |
| Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity. | Schmidt A et al. | β | 2015 | β |
| Potentiation of the expression of cocaine-induced sensitization by a conditioned stressor. | Sasaki A et al. | β | 2015 | β |
| Prenatal cocaine exposure differentially affects stress responses in girls and boys: associations with future substance use. | Chaplin TM et al. | β | 2015 | β |
| Relationship between drug dreams, affect, and craving during treatment for substance dependence. | Tanguay H et al. | β | 2015 | β |
| Reward processing and drug addiction: does sex matter? | Fattore L | β | 2015 | β |
| Alcohol: a stimulant activating brain stress responsive systems with persistent neuroadaptation. | Zhou Y et al. | β | 2014 | β |
| Altitude may contribute to regional variation in methamphetamine use in the United States: a population database study. | Kim TS et al. | β | 2014 | β |
| An alternative to the traditional cold pressor test: the cold pressor arm wrap. | Porcelli AJ | β | 2014 | β |
| Assessing craving and its relationship to subsequent prescription opioid use among treatment-seeking prescription opioid dependent patients. | McHugh RK et al. | β | 2014 | β |
| Can transcranial direct current stimulation (tDCS) alleviate symptoms and improve cognition in psychiatric disorders? | Mondino M et al. | β | 2014 | β |
| Connecting the pathology of posttraumatic stress and substance use disorders: monoamines and neuropeptides. | Enman NM et al. | β | 2014 | β |
| Correlates of polysomnographic sleep changes in cocaine dependence: self-administration and clinical outcomes. | Angarita GA et al. | β | 2014 | β |
| Deletion of the GABAA Ξ±2-subunit does not alter self administration of cocaine or reinstatement of cocaine seeking. | Dixon CI et al. | β | 2014 | β |
| Drug addiction and stress-response genetic variability: association study in African Americans. | Levran O et al. | β | 2014 | β |
| Drug withdrawal conceptualized as a stressor. | Chartoff EH et al. | β | 2014 | β |
| Dysregulation of diurnal cortisol secretion affects abstinence induction during a lead-in period of a clinical trial for depressed cocaine-dependent patients. | Raby WN et al. | β | 2014 | β |
| Effects of inhibitory GABA-active neurosteroids on cocaine seeking and cocaine taking in rats. | Schmoutz CD et al. | β | 2014 | β |
| Exercise for methamphetamine dependence: rationale, design, and methodology. | Mooney LJ et al. | β | 2014 | β |
| Food cravings, appetite, and snack-food consumption in response to a psychomotor stimulant drug: the moderating effect of "food-addiction". | Davis C et al. | β | 2014 | β |
| Future pharmacological treatments for substance use disorders. | Forray A et al. | β | 2014 | β |
| Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine. | Parnaudeau S et al. | β | 2014 | β |
| Modulation of proopiomelanocortin gene expression by ethanol in mouse anterior pituitary corticotrope tumor cell AtT20. | Zhou Y et al. | β | 2014 | β |
| Multisite, randomized, double-blind, placebo-controlled pilot clinical trial to evaluate the efficacy of buspirone as a relapse-prevention treatment for cocaine dependence. | Winhusen TM et al. | β | 2014 | β |
| Neurobiological mechanisms underlying relapse to cocaine use: contributions of CRF and noradrenergic systems and regulation by glucocorticoids. | McReynolds JR et al. | β | 2014 | β |
| Pharmacological means of reducing human drug dependence: a selective and narrative review of the clinical literature. | Lin SK | β | 2014 | β |
| Pickles and ice cream! Food cravings in pregnancy: hypotheses, preliminary evidence, and directions for future research. | Orloff NC et al. | β | 2014 | β |
| Re-appraisal of negative emotions in cocaine dependence: dysfunctional corticolimbic activation and connectivity. | Albein-Urios N et al. | β | 2014 | β |
| Stress in adolescence and drugs of abuse in rodent models: role of dopamine, CRF, and HPA axis. | Burke AR et al. | β | 2014 | β |
| The association between negative affect and prescription opioid misuse in patients with chronic pain: the mediating role of opioid craving. | Martel MO et al. | β | 2014 | β |
| The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions. | Goeders NE et al. | β | 2014 | β |
| The kappa opioid receptor: from addiction to depression, and back. | Lalanne L et al. | β | 2014 | β |
| The role of guanfacine as a therapeutic agent to address stress-related pathophysiology in cocaine-dependent individuals. | Fox H et al. | β | 2014 | β |
| Treatment of crack-cocaine dependence with topiramate: a randomized controlled feasibility trial in The Netherlands. | Nuijten M et al. | β | 2014 | β |
| Acute effects of heroin on emotions in heroin-dependent patients. | Blum J et al. | β | 2013 | β |
| A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans. | Saladin ME et al. | β | 2013 | β |
| Affective decision-making is predictive of three-month relapse in polysubstance-dependent alcoholics. | De Wilde B et al. | β | 2013 | β |
| Altered frontocingulate activation during aversive interoceptive processing in young adults transitioning to problem stimulant use. | Stewart JL et al. | β | 2013 | β |
| A narrative review of binge eating and addictive behaviors: shared associations with seasonality and personality factors. | Davis C | β | 2013 | β |
| Animal models of alcohol and drug dependence. | Planeta CS | β | 2013 | β |
| Assessing cue-induced brain response as a function of abstinence duration in heroin-dependent individuals: an event-related fMRI study. | Li Q et al. | β | 2013 | β |
| Associations among hypothalamus-pituitary-adrenal axis function, novelty seeking, and retention in methadone maintenance therapy for heroin dependency. | Lin SH et al. | β | 2013 | β |
| Atrial natriuretic peptide, arginine vasopressin peptide and cortisol serum levels in opiate-dependent patients. | Glahn A et al. | β | 2013 | β |
| A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk. | Xu K et al. | β | 2013 | β |
| Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. | Zorrilla EP et al. | β | 2013 | β |
| Brain stress system response after morphine-conditioned place preference. | GarcΓa-Carmona JA et al. | β | 2013 | β |
| Choice to view cocaine images predicts concurrent and prospective drug use in cocaine addiction. | Moeller SJ et al. | β | 2013 | β |
| Chronic childhood adversity and stages of substance use involvement in adolescents. | Benjet C et al. | β | 2013 | β |
| Corticosterone acts in the nucleus accumbens to enhance dopamine signaling and potentiate reinstatement of cocaine seeking. | Graf EN et al. | β | 2013 | β |
| Daily temporal patterns of heroin and cocaine use and craving: relationship with business hours regardless of actual employment status. | Phillips KA et al. | β | 2013 | β |
| Deficient plasticity in the hippocampus and the spiral of addiction: focus on adult neurogenesis. | Canales JJ | β | 2013 | β |
| Effects of non-invasive neurostimulation on craving: a meta-analysis. | Jansen JM et al. | β | 2013 | β |
| Exposure to traumatic experiences is associated with abnormal neural mechanism during charitable donation. | Wei D et al. | β | 2013 | β |
| Genetic influences on craving for alcohol. | Agrawal A et al. | β | 2013 | β |
| Influence of affective manipulations on cigarette craving: a meta-analysis. | Heckman BW et al. | β | 2013 | β |
| Involvement of dynorphin and kappa opioid receptor in yohimbine-induced reinstatement of heroin seeking in rats. | Zhou Y et al. | β | 2013 | β |
| Is it stress? The role of stress related systems in chronic food restriction-induced augmentation of heroin seeking in the rat. | Sedki F et al. | β | 2013 | β |
| Is virtual reality always an effective stressors for exposure treatments? Some insights from a controlled trial. | Pallavicini F et al. | β | 2013 | β |
| Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence. | Trifilieff P et al. | β | 2013 | β |
| Modeling relapse in animals. | Martin-Fardon R et al. | β | 2013 | β |
| Modeling relapse situations in the human laboratory. | Sinha R | β | 2013 | β |
| New developments in behavioral treatments for substance use disorders. | Kiluk BD et al. | β | 2013 | β |
| Stress system changes associated with marijuana dependence may increase craving for alcohol and cocaine. | Fox HC et al. | β | 2013 | β |
| Suppression of hypothalamic-pituitary-adrenal axis by acute heroin challenge in rats during acute and chronic withdrawal from chronic heroin administration. | Zhou Y et al. | β | 2013 | β |
| The clinical neurobiology of drug craving. | Sinha R | β | 2013 | β |
| The effects of exogenous progesterone on drug craving and stress arousal in cocaine dependence: impact of gender and cue type. | Fox HC et al. | β | 2013 | β |
| The effects of varied extinction procedures on contingent cue-induced reinstatement in Sprague-Dawley rats. | Buffalari DM et al. | β | 2013 | β |
| The impact of adolescent binge drinking and sustained abstinence on affective state. | Bekman NM et al. | β | 2013 | β |
| The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. | Bossert JM et al. | β | 2013 | β |
| Beyond drug use: a systematic consideration of other outcomes in evaluations of treatments for substance use disorders. | Tiffany ST et al. | β | 2012 | β |
| Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats. | Chartoff E et al. | β | 2012 | β |
| Blunted vagal reactivity predicts stress-precipitated tobacco smoking. | Ashare RL et al. | β | 2012 | β |
| Corticotrophin releasing factor (CRF) induced reinstatement of cocaine seeking in male and female rats. | Buffalari DM et al. | β | 2012 | β |
| Cue-induced reinstatement of cocaine seeking in the rat "conflict model": effect of prolonged home-cage confinement. | Barnea-Ygael N et al. | β | 2012 | β |
| Differential modulation of cocaine's discriminative cue by repeated and variable stress exposure: relation to monoamine transporter levels. | Kohut SJ et al. | β | 2012 | β |
| Effect of yohimbine stress on reacquisition of oxycodone seeking in rats. | Campbell AT et al. | β | 2012 | β |
| Enhanced anxiety observed in cocaine withdrawn rats is associated with altered reactivity of the dorsomedial prefrontal cortex. | El Hage C et al. | β | 2012 | β |
| Evaluation of buspirone for relapse-prevention in adults with cocaine dependence: an efficacy trial conducted in the real world. | Winhusen T et al. | β | 2012 | β |
| Genetic modulation of plasma NPY stress response is suppressed in substance abuse: association with clinical outcomes. | Xu K et al. | β | 2012 | β |
| Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings. | Fox HC et al. | β | 2012 | β |
| Hair cortisol and stressful life events retrospective assessment in crack cocaine users. | Grassi-Oliveira R et al. | β | 2012 | β |
| How does stress lead to risk of alcohol relapse? | Sinha R | β | 2012 | β |
| Immune system inflammation in cocaine dependent individuals: implications for medications development. | Fox HC et al. | β | 2012 | β |
| Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence. | Potenza MN et al. | β | 2012 | β |
| Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. | Kreek MJ et al. | β | 2012 | β |
| Pharmacologically-mediated reactivation and reconsolidation blockade of the psychostimulant-abuse circuit: a novel treatment strategy. | Lee TH et al. | β | 2012 | β |
| Self-regulation and treatment retention in cocaine dependent individuals: a longitudinal study. | Verdejo-GarcΓa A et al. | β | 2012 | β |
| Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis. | Becker JB et al. | β | 2012 | β |
| STimulant Reduction Intervention using Dosed Exercise (STRIDE) - Description of the Exercise Intervention and Behavioral Program to Ensure Adherence. | Stoutenberg M et al. | β | 2012 | β |
| TGI Monday?: drug-dependent outpatients report lower stress and more happiness at work than elsewhere. | Epstein DH et al. | β | 2012 | β |
| The impact of diacetylmorphine on hypothalamic-pituitary-adrenal axis activity and heroin craving in heroin dependence. | Gerber H et al. | β | 2012 | β |
| The Obsessive-Compulsive Cocaine Scale (OCCS): a pilot study of a new questionnaire for assessing cocaine craving. | Vorspan F et al. | β | 2012 | β |
| The Obsessive Compulsive Cocaine Use Scale: development and initial validation of a self-rated instrument for the quantification of thoughts about cocaine use. | Hormes JM et al. | β | 2012 | β |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. | Breese GR et al. | β | 2011 | β |
| Chronic cocaine self-administration attenuates the anxiogenic-like and stress potentiating effects of the benzodiazepine inverse agonist, FG 7142. | Waters RP et al. | β | 2011 | β |
| Cocaine Dependence Treatment Data: Methods for Measurement Error Problems With Predictors Derived From Stationary Stochastic Processes. | Guan Y et al. | β | 2011 | β |
| Cue-induced reactivity, cortisol response and substance use outcome in treated heroin dependent individuals. | Fatseas M et al. | β | 2011 | β |
| Effects of progesterone and testosterone on cocaine self-administration and cocaine discrimination by female rhesus monkeys. | Mello NK et al. | β | 2011 | β |
| Hidden Markov models for zero-inflated Poisson counts with an application to substance use. | DeSantis SM et al. | β | 2011 | β |
| Inactivation of the bed nucleus of the stria terminalis in an animal model of relapse: effects on conditioned cue-induced reinstatement and its enhancement by yohimbine. | Buffalari DM et al. | β | 2011 | β |
| Increased serum brain-derived neurotrophic factor is predictive of cocaine relapse outcomes: a prospective study. | D'Sa C et al. | β | 2011 | β |
| Negative mood induction normalizes decision making in male cocaine dependent individuals. | FernΓ‘ndez-Serrano MJ et al. | β | 2011 | β |
| Neuroscience of behavioral and pharmacological treatments for addictions. | Potenza MN et al. | β | 2011 | β |
| New findings on biological factors predicting addiction relapse vulnerability. | Sinha R | β | 2011 | β |
| Nicotine as a factor in stress responsiveness among detoxified alcoholics. | Gilbertson R et al. | β | 2011 | β |
| Persistent increase in hypothalamic arginine vasopressin gene expression during protracted withdrawal from chronic escalating-dose cocaine in rodents. | Zhou Y et al. | β | 2011 | β |
| Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. | Umhau JC et al. | β | 2011 | β |
| Predictive value of obsessive-compulsive drinking scale (OCDS) for outcome in alcohol-dependent inpatients: results of a 24-month follow-up study. | Schmidt P et al. | β | 2011 | β |
| Prevention of social stress-escalated cocaine self-administration by CRF-R1 antagonist in the rat VTA. | Boyson CO et al. | β | 2011 | β |
| Psychometric properties of the Chinese craving beliefs questionnaire for heroin abusers in methadone treatment. | Chang CW et al. | β | 2011 | β |
| Selective cocaine-related difficulties in emotional intelligence: relationship to stress and impulse control. | Fox HC et al. | β | 2011 | β |
| Sex differences in neural responses to stress and alcohol context cues. | Seo D et al. | β | 2011 | β |
| Stress and cocaine interact to modulate Arc/Arg3.1 expression in rat brain. | Caffino L et al. | β | 2011 | β |
| Stress in the daily lives of cocaine and heroin users: relationship to mood, craving, relapse triggers, and cocaine use. | Preston KL et al. | β | 2011 | β |
| The effects of oral micronized progesterone on smoked cocaine self-administration in women. | Reed SC et al. | β | 2011 | β |
| Translational and reverse translational research on the role of stress in drug craving and relapse. | Sinha R et al. | β | 2011 | β |
| Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? | Heilig M et al. | β | 2010 | β |
| Anxiety-like responses in adolescent rats following a 10-11-day withdrawal period from repeated cocaine administration. | Santucci AC et al. | β | 2010 | β |
| Behavioral arousal in response to stress and drug cue in alcohol and cocaine addicted individuals versus healthy controls. | Chaplin TM et al. | β | 2010 | β |
| Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms. | Schindler AG et al. | β | 2010 | β |
| Chronic amphetamine treatment enhances corticotropin-releasing factor-induced serotonin release in the amygdala. | Scholl JL et al. | β | 2010 | β |
| Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues. | Waldrop AE et al. | β | 2010 | β |
| Consilient research approaches in studying gene x environment interactions in alcohol research. | Sher KJ et al. | β | 2010 | β |
| Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases. | Zhou Y et al. | β | 2010 | β |
| Imagery scripts and a computerized subtraction stress task both induce stress in methamphetamine users: a controlled laboratory study. | Garrison KJ et al. | β | 2010 | β |
| Increased anxiety-like behavior of rats during amphetamine withdrawal is reversed by CRF2 receptor antagonism. | Vuong SM et al. | β | 2010 | β |
| Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice. | Zhou Y et al. | β | 2010 | β |
| Mindfulness-based treatments for co-occurring depression and substance use disorders: what can we learn from the brain? | Brewer JA et al. | β | 2010 | β |
| OCDS craving scores predict 24-month outcome in alcoholic outpatients. | Soyka M et al. | β | 2010 | β |
| Patterns of childhood trauma and psychological distress among injecting heroin users in China. | Wang Z et al. | β | 2010 | β |
| Pharmacologically-induced stress: a cross-species probe for translational research in drug addiction and relapse. | See RE et al. | β | 2010 | β |
| Progesterone attenuates cocaine-induced responses. | Quinones-Jenab V et al. | β | 2010 | β |
| Reactivity to laboratory stress provocation predicts relapse to cocaine. | Back SE et al. | β | 2010 | β |
| Self-reports of interoceptive responses during stress and drug cue-related experiences in cocaine- and alcohol-dependent individuals. | Bergquist KL et al. | β | 2010 | β |
| Sex differences in the effects of allopregnanolone on yohimbine-induced reinstatement of cocaine seeking in rats. | Anker JJ et al. | β | 2010 | β |
| Stress-induced reinstatement of amphetamine-conditioned place preference and changes in tyrosine hydroxylase in the nucleus accumbens in adolescent rats. | Cruz FC et al. | β | 2010 | β |
| The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse. | Van Bockstaele EJ et al. | β | 2010 | β |
| What's new in the treatment of cocaine addiction? | Kampman KM | β | 2010 | β |
| A double-blind, placebo-controlled trial of modafinil (200 mg/day) for methamphetamine dependence. | Shearer J et al. | β | 2009 | β |
| An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | Mangieri RA et al. | β | 2009 | β |
| Anti-relapse medications: preclinical models for drug addiction treatment. | Yahyavi-Firouz-Abadi N et al. | β | 2009 | β |
| Bidirectional translational research: Progress in understanding addictive diseases. | Kreek MJ et al. | β | 2009 | β |
| Biologic Commonalities between Mental Illness and Addiction. | Hartwell KJ et al. | β | 2009 | β |
| Clinical and laboratory assessment of the subjective experience of drug craving. | Rosenberg H | β | 2009 | β |
| Cocaine craving and use during daily life. | Preston KL et al. | β | 2009 | β |
| Daily ratings measures of alcohol craving during an inpatient stay define subtypes of alcohol addiction that predict subsequent risk for resumption of drinking. | Oslin DW et al. | β | 2009 | β |
| Development of pharmacotherapies for drug addiction: a Rosetta stone approach. | Koob GF et al. | β | 2009 | β |
| Elevated cortisol and learning and memory deficits in cocaine dependent individuals: relationship to relapse outcomes. | Fox HC et al. | β | 2009 | β |
| Enhanced choice for viewing cocaine pictures in cocaine addiction. | Moeller SJ et al. | β | 2009 | β |
| Enhanced negative emotion and alcohol craving, and altered physiological responses following stress and cue exposure in alcohol dependent individuals. | Sinha R et al. | β | 2009 | β |
| Extinction circuits for fear and addiction overlap in prefrontal cortex. | Peters J et al. | β | 2009 | β |
| Footshock stress potentiates cue-induced cocaine-seeking in an animal model of relapse. | Buffalari DM et al. | β | 2009 | β |
| Gene-environment interactions resulting in risk alcohol drinking behaviour are mediated by CRF and CRF1. | Clarke TK et al. | β | 2009 | β |
| HPA axis response to psychological stress and treatment retention in residential substance abuse treatment: a prospective study. | Daughters SB et al. | β | 2009 | β |
| Influence of verbal recall of a recent stress experience on anxiety and desire for cocaine in non-treatment seeking, cocaine-addicted volunteers. | De La Garza R et al. | β | 2009 | β |
| mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse. | Gaval-Cruz M et al. | β | 2009 | β |
| Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study. | Brewer JA et al. | β | 2009 | β |
| Modeling stress and drug craving in the laboratory: implications for addiction treatment development. | Sinha R | β | 2009 | β |
| New dimensions in human laboratory models of addiction. | Koob GF | β | 2009 | β |
| Non-treatment laboratory stress- and cue-reactivity studies are associated with decreased substance use among drug-dependent individuals. | DeSantis SM et al. | β | 2009 | β |
| Opiate and cocaine addiction: from bench to clinic and back to the bench. | Kreek MJ et al. | β | 2009 | β |
| Repeated stress prevents cocaine-induced activation of BDNF signaling in rat prefrontal cortex. | Fumagalli F et al. | β | 2009 | β |
| Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. | Brady KT et al. | β | 2009 | β |
| Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. | Fox HC et al. | β | 2009 | β |
| Sex-specific dissociations in autonomic and HPA responses to stress and cues in alcohol-dependent patients with cocaine abuse. | Fox HC et al. | β | 2009 | β |
| Social experiences affect reinstatement of cocaine-induced place preference in mice. | Ribeiro Do Couto B et al. | β | 2009 | β |
| Stress, alcohol and drug interaction: an update of human research. | Uhart M et al. | β | 2009 | β |
| Stress-related factors in cannabis use and misuse: implications for prevention and treatment. | Hyman SM et al. | β | 2009 | β |
| The role of anxiety sensitivity and difficulties in emotion regulation in posttraumatic stress disorder among crack/cocaine dependent patients in residential substance abuse treatment. | McDermott MJ et al. | β | 2009 | β |
| Trait anxiety and ethanol: anxiolysis in high-anxiety mice and no relation to intake behavior in an addiction model. | Correia D et al. | β | 2009 | β |
| Vaccines for cocaine abuse. | Orson FM et al. | β | 2009 | β |
| WITHDRAWN: Anti-relapse medications: Preclinical models for drug addiction treatment. | Yahyavi-Firouz-Abadi N et al. | β | 2009 | β |
| Adrenocorticotropic hormone and cortisol plasma levels directly correlate with childhood neglect and depression measures in addicted patients. | Gerra G et al. | β | 2008 | β |
| Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females. | Fox HC et al. | β | 2008 | β |
| Attentional Bias to Drug- and Stress-Related Pictorial Cues in Cocaine Addiction Comorbid with PTSD. | Sokhadze E et al. | β | 2008 | β |
| Chronic stress, drug use, and vulnerability to addiction. | Sinha R | β | 2008 | β |
| Craving predicts time to cocaine relapse: further validation of the Now and Brief versions of the cocaine craving questionnaire. | Paliwal P et al. | β | 2008 | β |
| Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers. | Fox HC et al. | β | 2008 | β |
| Gender differences in response to emotional stress: an assessment across subjective, behavioral, and physiological domains and relations to alcohol craving. | Chaplin TM et al. | β | 2008 | β |
| Gender differences in zebrafish responses to cocaine withdrawal. | LΓ³pez PatiΓ±o MA et al. | β | 2008 | β |
| Genetic variation in human NPY expression affects stress response and emotion. | Zhou Z et al. | β | 2008 | β |
| Inhibitory control and emotional stress regulation: neuroimaging evidence for frontal-limbic dysfunction in psycho-stimulant addiction. | Li CS et al. | β | 2008 | β |
| Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin. | Zhou Y et al. | β | 2008 | β |
| Lack of relation between drug-seeking behavior in an addiction model and the expression of behavioral sensitization in response to ethanol challenge in mice. | Ribeiro AF et al. | β | 2008 | β |
| Naltrexone effect on physiological and subjective response to a cold pressor task. | Kotlyar M et al. | β | 2008 | β |
| Neuropharmacology of glucocorticoids: focus on emotion, cognition and cocaine. | de Kloet ER et al. | β | 2008 | β |
| New treatments for cocaine dependence: a focused review. | Karila L et al. | β | 2008 | β |
| Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence. | Smith RJ et al. | β | 2008 | β |
| Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients. | Brewer JA et al. | β | 2008 | β |
| Psychobiological responses to drug cues before and after methadone intake in heroin-dependent patients: a pilot study. | Walter M et al. | β | 2008 | β |
| Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during abstinence. | Aujla H et al. | β | 2008 | β |
| Role of a functional human gene polymorphism in stress responsivity and addictions. | Kreek MJ | β | 2008 | β |
| Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men. | Hyman SM et al. | β | 2008 | β |
| Stress and Rodent Models of Drug Addiction: Role of VTA-Accumbens-PFC-Amygdala Circuit. | Yap JJ et al. | β | 2008 | β |
| The effect of stress on craving for methadone depends on the timing of last methadone dose. | Ilgen M et al. | β | 2008 | β |
| The influence of stress on the transition from drug use to addiction. | Wand G | β | 2008 | β |
| Time-of-day differences in dopamine clearance in the rat medial prefrontal cortex and nucleus accumbens. | Sleipness EP et al. | β | 2008 | β |
| Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress. | Wand GS et al. | β | 2007 | β |
| Augmentation of methamphetamine-induced toxicity in the rat striatum by unpredictable stress: contribution of enhanced hyperthermia. | Tata DA et al. | β | 2007 | β |
| Childhood maltreatment, perceived stress, and stress-related coping in recently abstinent cocaine dependent adults. | Hyman SM et al. | β | 2007 | β |
| Cognitive-behavioral stress management for individuals with substance use disorders: a pilot study. | Back SE et al. | β | 2007 | β |
| Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats. | Mantsch JR et al. | β | 2007 | β |
| Daily stressor sensitivity, abuse effects, and cocaine use in cocaine dependence. | Waldrop AE et al. | β | 2007 | β |
| Decreases in dietary preference produce increased emotionality and risk for dietary relapse. | Teegarden SL et al. | β | 2007 | β |
| Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. | Sinha R et al. | β | 2007 | β |
| Gender and stimulus difference in cue-induced responses in abstinent heroin users. | Yu J et al. | β | 2007 | β |
| Imaging stress- and cue-induced drug and alcohol craving: association with relapse and clinical implications. | Sinha R et al. | β | 2007 | β |
| Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction. | Tata DA et al. | β | 2007 | β |
| Location, location: using functional magnetic resonance imaging to pinpoint brain differences relevant to stimulant use. | Aron JL et al. | β | 2007 | β |
| Negative emotion-driven impulsivity predicts substance dependence problems. | Verdejo-GarcΓa A et al. | β | 2007 | β |
| New developments in the pharmacotherapy of cocaine abuse. | Preti A | β | 2007 | β |
| Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration. | Mantsch JR et al. | β | 2007 | β |
| Stress- and cue-induced cigarette craving: effects of a family history of smoking. | Colamussi L et al. | β | 2007 | β |
| Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment. | Hyman SM et al. | β | 2007 | β |
| Stress, dysregulation of drug reward pathways, and the transition to drug dependence. | Koob G et al. | β | 2007 | β |
| Stress-induced and alcohol cue-induced craving in recently abstinent alcohol-dependent individuals. | Fox HC et al. | β | 2007 | β |
| The role of stress in addiction relapse. | Sinha R | β | 2007 | β |
| The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. | Kroslak T et al. | β | 2007 | β |
| Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon. | Carrasco GA et al. | β | 2006 | β |
| Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys. | Mello NK et al. | β | 2006 | β |
| On blending practice and research: the search for commonalities in substance abuse treatment. | Kellogg S et al. | β | 2006 | β |