Selective breeding for alcohol preference and associated responses.
paper
Cited
Public
Unavailable
- Authors
- Li, T K; Lumeng, L; Doolittle, D P
- Year
- 1993
- Journal
- Behavior genetics
- PMID
- 8099788
- DOI
- 10.1007/BF01067421
Selective breeding for high and low alcohol-drinking preference has produced rat lines useful for studying the nature of excessive alcohol-seeking behavior. Compared with the alcohol-nonpreferring line, the preferring animals exhibit heightened responsivity to the low-dose activating effects of ethanol as well as enhanced capacity for developing tolerance to the aversive, behaviorally impairing effects of ethanol. The preferring animals exhibit lower brain serotonin and dopamine neurotransmitter activity as well as differences in other neurotransmitter neuromodulator systems, compared with the alcohol-nonpreferring animals.
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|---|---|---|---|---|
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| Behavioral consequences of the downstream products of ethanol metabolism involved in alcohol use disorder. | Holbrook OT et al. | β | 2022 | β |
| Genetic Vulnerability to Opioid Addiction. | Reed B et al. | β | 2021 | β |
| High ethanol preference and dissociated memory are co-occurring phenotypes associated with hippocampal GABA<sub>A</sub>R-Ξ΄ receptor levels. | Jovasevic V et al. | β | 2021 | β |
| Administration of a putative pro-dopamine regulator, a neuronutrient, mitigates alcohol intake in alcohol-preferring rats. | Solanki N et al. | β | 2020 | β |
| Differential expression of ΞΌ-opioid receptors in the nucleus accumbens, amygdala and VTA depends on liking for alcohol, chronic alcohol intake and estradiol treatment. | Molina-MartΓnez LM et al. | β | 2020 | β |
| Epigenetic changes on rat chromosome 4 contribute to disparate alcohol drinking behavior in alcohol-preferring and -nonpreferring rats. | Spence JP et al. | β | 2020 | β |
| Leveraging Neural Networks in Preclinical Alcohol Research. | Smith LC et al. | β | 2020 | β |
| Pre-clinical models of reward deficiency syndrome: A behavioral octopus. | GondrΓ©-Lewis MC et al. | β | 2020 | β |
| Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. | Althobaiti YS et al. | β | 2019 | β |
| The Rat: A Model Used in Biomedical Research. | Smith JR et al. | β | 2019 | β |
| Delta Opioid Pharmacology in Relation to Alcohol Behaviors. | Alongkronrusmee D et al. | β | 2018 | β |
| Estrogen-Dependent Upregulation of <i>Adcyap1r1</i> Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4. | Spence JP et al. | β | 2018 | β |
| Low Inherent Sensitivity to the Intoxicating Effects of Ethanol in Rhesus Monkeys with Low CSF Concentrations of the Serotonin Metabolite 5-Hydroxyindoleacetic Acid. | Wood EK et al. | β | 2018 | β |
| Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour. | Wood CM et al. | β | 2017 | β |
| Alcohol enhances unprovoked 22-28 kHz USVs and suppresses USV mean frequency in High Alcohol Drinking (HAD-1) male rats. | Thakore N et al. | β | 2016 | β |
| Alcohol intake may impair bone density and new cementum formation after enamel matrix derivative treatment: histometric study in rats. | CorrΓͺa MG et al. | β | 2016 | β |
| Consumption of Substances of Abuse during Pregnancy Increases Consumption in Offspring: Possible Underlying Mechanisms. | Poon K et al. | β | 2016 | β |
| Ethanol-induced conditioned taste aversion in Warsaw Alcohol High-Preferring (WHP) and Warsaw Alcohol Low-Preferring (WLP) rats. | Dyr W et al. | β | 2016 | β |
| The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats. | Augier E et al. | β | 2016 | β |
| Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive. | PeΓ±a-Oliver Y et al. | β | 2015 | β |
| Low copulatory activity in selectively bred Sardinian alcohol-nonpreferring (sNP) relative to alcohol-preferring (sP) rats. | Karlsson O et al. | β | 2015 | β |
| The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption. | Saba LM et al. | β | 2015 | β |
| Early ethanol and water intake: choice mechanism and total fluid regulation operate in parallel in male alcohol preferring (P) and both Wistar and Sprague Dawley rats. | Azarov AV et al. | β | 2014 | β |
| Effects of histone deacetylase inhibitors on amygdaloid histone acetylation and neuropeptide Y expression: a role in anxiety-like and alcohol-drinking behaviours. | Sakharkar AJ et al. | β | 2014 | β |
| Genetics of gene expression characterizes response to selective breeding for alcohol preference. | Hoffman PL et al. | β | 2014 | β |
| Gut-brain peptides in corticostriatal-limbic circuitry and alcohol use disorders. | Vadnie CA et al. | β | 2014 | β |
| Intravenous alcohol self-administration in the P rat. | Windisch KA et al. | β | 2014 | β |
| Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains. | Vanderlinden LA et al. | β | 2014 | β |
| Perspectives on the neuroscience of alcohol from the National Institute on Alcohol Abuse and Alcoholism. | Reilly MT et al. | β | 2014 | β |
| The alcohol-preferring (P) and high-alcohol-drinking (HAD) rats--animal models of alcoholism. | McBride WJ et al. | β | 2014 | β |
| Alterations in ethanol seeking and self-administration following yohimbine in selectively bred alcohol-preferring (P) and high alcohol drinking (HAD-2) rats. | Bertholomey ML et al. | β | 2013 | β |
| Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone. | Froehlich JC et al. | β | 2013 | β |
| Gene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption. | McBride WJ et al. | β | 2013 | β |
| Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. | Zhou Z et al. | β | 2013 | β |
| Nine generations of selection for high and low nicotine intake in outbred Sprague-Dawley rats. | Nesil T et al. | β | 2013 | β |
| Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity. | Bell RL et al. | β | 2012 | β |
| Animal models of psychiatric disorders. | Koob GF | β | 2012 | β |
| Behavioral profiling of multiple pairs of rats selectively bred for high and low alcohol intake using the MCSF test. | Roman E et al. | β | 2012 | β |
| Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. | McBride WJ et al. | β | 2012 | β |
| Medications development to treat alcohol dependence: a vision for the next decade. | Litten RZ et al. | β | 2012 | β |
| Neurobiology of consummatory behavior: mechanisms underlying overeating and drug use. | Barson JR et al. | β | 2012 | β |
| Neuropeptide Y (NPY) in the central nucleus of the amygdala (CeA) does not affect ethanol-reinforced responding in binge-drinking, nondependent rats. | Henderson AN et al. | β | 2012 | β |
| Rodent models of alcoholic liver disease: of mice and men. | Brandon-Warner E et al. | β | 2012 | β |
| Selectively bred rodents as models of depression and anxiety. | Wegener G et al. | β | 2012 | β |
| Advances in animal models of drug addiction. | Heidbreder C | β | 2011 | β |
| Age differences in the expression of acute and chronic tolerance to ethanol in male and female rats. | Morales M et al. | β | 2011 | β |
| Alcohol induces liver neoplasia in a novel alcohol-preferring rat model. | Yip-Schneider MT et al. | β | 2011 | β |
| Derivation and characterization of replicate high- and low-alcohol preferring lines of mice and a high-drinking crossed HAP line. | Oberlin B et al. | β | 2011 | β |
| Diverse behavioral, monoaminergic and Fos protein responses to opioids in Warsaw high-alcohol preferring and Warsaw low-alcohol preferring rats. | Taracha E et al. | β | 2011 | β |
| Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress. | West CH et al. | β | 2011 | β |
| Genetic propensities to increase ethanol intake in response to stress: studies with selectively bred swim test susceptible (SUS), alcohol-preferring (P), and non-preferring (NP) lines of rats. | Bertholomey ML et al. | β | 2011 | β |
| Imaging of alcohol-induced dopamine release in rats:preliminary findings with [(11) C]raclopride PET. | Sullivan JM et al. | β | 2011 | β |
| Increased ethanol consumption and preference in mice lacking neurotensin receptor type 2. | Lee MR et al. | β | 2011 | β |
| Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening. | Gorini G et al. | β | 2011 | β |
| The role of amygdaloid brain-derived neurotrophic factor, activity-regulated cytoskeleton-associated protein and dendritic spines in anxiety and alcoholism. | Moonat S et al. | β | 2011 | β |
| Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats. | Liang T et al. | β | 2010 | β |
| Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats. | Rezvani AH et al. | β | 2010 | β |
| Event-related oscillations in the parietal cortex of adult alcohol-preferring (P) and alcohol-nonpreferring rats (NP). | Criado JR et al. | β | 2010 | β |
| Fine mapping and expression of candidate genes within the chromosome 10 QTL region of the high and low alcohol-drinking rats. | Bice PJ et al. | β | 2010 | β |
| Neuropeptide Y signaling in the central nucleus of amygdala regulates alcohol-drinking and anxiety-like behaviors of alcohol-preferring rats. | Zhang H et al. | β | 2010 | β |
| Neuroscience of alcoholism: molecular and cellular mechanisms. | Moonat S et al. | β | 2010 | β |
| Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol. | Rezvani AH et al. | β | 2010 | β |
| Rats selectively bred for ethanol preference or nonpreference have altered working memory. | Wenger GR et al. | β | 2010 | β |
| The 10 most important things known about addiction. | Sellman D | β | 2010 | β |
| What neurobiology cannot tell us about addiction. | Kalant H | β | 2010 | β |
| Abstinence from moderate alcohol self-administration alters progenitor cell proliferation and differentiation in multiple brain regions of male and female P rats. | He J et al. | β | 2009 | β |
| Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of high-alcohol-drinking (HAD) rats. | Rodd ZA et al. | β | 2009 | β |
| Effects of forced alcohol drinking on alcohol-water choice in three pairs of rat lines selectively bred for differences in alcohol preference. | Timberlake W et al. | β | 2009 | β |
| Lower risk taking and exploratory behavior in alcohol-preferring sP rats than in alcohol non-preferring sNP rats in the multivariate concentric square field (MCSF) test. | Roman E et al. | β | 2009 | β |
| Ethanol drinking in rodents: is free-choice drinking related to the reinforcing effects of ethanol? | Green AS et al. | β | 2008 | β |
| Innate differences in the expression of brain-derived neurotrophic factor in the regions within the extended amygdala between alcohol preferring and nonpreferring rats. | Prakash A et al. | β | 2008 | β |
| Learning in the 2-bottle alcohol preference test. | Blizard DA et al. | β | 2008 | β |
| Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. | Wetherill L et al. | β | 2008 | β |
| Quantitative chiral analysis of salsolinol in different brain regions of rats genetically predisposed to alcoholism. | Rojkovicova T et al. | β | 2008 | β |
| Rats selectively-bred for behavior related to affective disorders: proclivity for intake of alcohol and drugs of abuse, and measures of brain monoamines. | Weiss JM et al. | β | 2008 | β |
| Schedule-induced polydipsia in lines of rats selectively bred for high and low ethanol preference. | Gilpin NW et al. | β | 2008 | β |
| Selective breeding for differential saccharin intake as an animal model of drug abuse. | Carroll ME et al. | β | 2008 | β |
| Translational studies of alcoholism: bridging the gap. | Zahr NM et al. | β | 2008 | β |
| Application of proteomic technologies to discover and identify biomarkers for excessive alcohol consumption: a review. | Nomura F et al. | β | 2007 | β |
| Association of alcohol craving with alpha-synuclein (SNCA). | Foroud T et al. | β | 2007 | β |
| Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control. | Overstreet DH et al. | β | 2007 | β |
| Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol. | Quintanilla ME et al. | β | 2007 | β |
| Further genetic characterization of the fawn-hooded (FH/Wjd) rat, an animal model of comorbid depression and alcoholism. | Rezvani AH et al. | β | 2007 | β |
| Higher locomotor response to cocaine in female (vs. male) rats selectively bred for high (HiS) and low (LoS) saccharin intake. | Carroll ME et al. | β | 2007 | β |
| Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. | Carr LG et al. | β | 2007 | β |
| Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41). | Finn DA et al. | β | 2007 | β |
| Matching law choice analyses of ethanol and sucrose consumption in alcohol-preferring (P), nonpreferring (NP), and Sprague-Dawley (SD) rats. | Martinetti MP et al. | β | 2007 | β |
| Changes in liver protein abundance in inbred alcohol-preferring rats due to chronic alcohol exposure, as measured through a proteomics approach. | Klouckova I et al. | β | 2006 | β |
| Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats. | Carroll MR et al. | β | 2006 | β |
| Comparison of VTA dopamine neuron activity in lines of rats selectively bred to prefer or avoid alcohol. | Morzorati SL et al. | β | 2006 | β |
| Differential effects of alcohol consumption and withdrawal on circadian temperature and activity rhythms in Sprague-Dawley, Lewis, and Fischer male and female rats. | Taylor AN et al. | β | 2006 | β |
| Effects of multiple alcohol deprivations on operant ethanol self-administration by high-alcohol-drinking replicate rat lines. | Oster SM et al. | β | 2006 | β |
| Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. | OffenhΓ€user N et al. | β | 2006 | β |
| Increased vulnerability to nicotine self-administration and relapse in alcohol-naive offspring of rats selectively bred for high alcohol intake. | LΓͺ AD et al. | β | 2006 | β |
| Intake of ethanol and reinforcing fluids in rats bred for susceptibility to stress. | West CH et al. | β | 2006 | β |
| Limited-access consumption of ascending ethanol concentrations in alcohol-preferring, nonpreferring, and Sprague-Dawley rats. | Martinetti MP et al. | β | 2006 | β |
| Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment. | Overstreet DH et al. | β | 2006 | β |
| Nitrous oxide acutely suppresses ethanol consumption in HAD and P rats. | Kosobud AE et al. | β | 2006 | β |
| The decreased cyclic-AMP dependent-protein kinase A function in the nucleus accumbens: a role in alcohol drinking but not in anxiety-like behaviors in rats. | Misra K et al. | β | 2006 | β |
| The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse. | Vengeliene V et al. | β | 2006 | β |
| A procedure to produce high alcohol intake in mice. | Finn DA et al. | β | 2005 | β |
| Bone mass and strength: phenotypic and genetic relationship to alcohol preference in P/NP and HAD/LAD rats. | Alam I et al. | β | 2005 | β |
| Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. | Pandey SC et al. | β | 2005 | β |
| Effect of social isolation on ethanol consumption and substance P/neurokinin expression in Wistar rats. | Thorsell A et al. | β | 2005 | β |
| Effects of chronic alcohol treatment on acoustic startle reactivity during withdrawal and subsequent alcohol intake in high and low alcohol drinking rats. | Chester JA et al. | β | 2005 | β |
| Escalation of intravenous cocaine self-administration, progressive-ratio performance, and reinstatement in rats selectively bred for high (HiS) and low (LoS) saccharin intake. | Morgan AD et al. | β | 2005 | β |
| Genetic correlational analyses of ethanol reward and aversion phenotypes in short-term selected mouse lines bred for ethanol drinking or ethanol-induced conditioned taste aversion. | Phillips TJ et al. | β | 2005 | β |
| Pharmacological modulation of repeated ethanol withdrawal-induced anxiety-like behavior differs in alcohol-preferring P and Sprague-Dawley rats. | Overstreet DH et al. | β | 2005 | β |
| The anxious amygdala: CREB signaling and predisposition to anxiety and alcoholism. | Wand G | β | 2005 | β |
| Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. | Worst TJ et al. | β | 2005 | β |
| Acoustic startle reactivity during acute alcohol withdrawal in rats that differ in genetic predisposition toward alcohol drinking: effect of stimulus characteristics. | Chester JA et al. | β | 2004 | β |
| Confirmation and genetic dissection of a major quantitative trait locus for alcohol preference drinking. | Ruf C et al. | β | 2004 | β |
| Corticotropin-releasing factor gene expression is down-regulated in the central nucleus of the amygdala of alcohol-preferring rats which exhibit high anxiety: a comparison between rat lines selectively bred for high and low alcohol preference. | Hwang BH et al. | β | 2004 | β |
| Immediate acceptance of ethanol in infant rats: ontogenetic differences with moderate but not high ethanol concentration. | Truxell E et al. | β | 2004 | β |
| Innate differences in neuropeptide Y (NPY) mRNA expression in discrete brain regions between alcohol-preferring (P) and -nonpreferring (NP) rats: a significantly low level of NPY mRNA in dentate gyrus of the hippocampus and absence of NPY mRNA in the medial habenular nucleus of P rats. | Hwang BH et al. | β | 2004 | β |
| Low-dose stimulatory effects of ethanol during adolescence in rat lines selectively bred for high alcohol intake. | Rodd ZA et al. | β | 2004 | β |
| Magnetic resonance detects brainstem changes in chronic, active heavy drinkers. | Bloomer CW et al. | β | 2004 | β |
| Motor impairing effects of ethanol and diazepam in rats selectively bred for high and low ethanol consumption in a limited-access paradigm. | Shram MJ et al. | β | 2004 | β |
| Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors. | Pandey SC et al. | β | 2004 | β |
| Protein kinase C isozymes and addiction. | Olive MF et al. | β | 2004 | β |
| Recent advances in animal models of alcohol craving and relapse. | Rodd ZA et al. | β | 2004 | β |
| Reduced neuropeptide Y mRNA expression in the central nucleus of amygdala of alcohol preferring (P) rats: its potential involvement in alcohol preference and anxiety. | Suzuki R et al. | β | 2004 | β |
| The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of alcohol addiction. | Pandey SC | β | 2004 | β |
| The High-Ethanol Preferring rat as a model to study the shift between alcohol abuse and dependence. | Terenina-Rigaldie E et al. | β | 2004 | β |
| The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. | Gonzales RA et al. | β | 2004 | β |
| The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference. | Choi DS et al. | β | 2004 | β |
| AA and ANA rats exhibit the R100Q mutation in the GABAA receptor alpha 6 subunit. | Carr LG et al. | β | 2003 | β |
| A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake. | Vengeliene V et al. | β | 2003 | β |
| Alcohol addiction research: from animal models to clinics. | Spanagel R | β | 2003 | β |
| Alcoholism: allostasis and beyond. | Koob GF | β | 2003 | β |
| Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats. | Carr LG et al. | β | 2003 | β |
| Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology. | Koob GF et al. | β | 2003 | β |
| Anxiety and alcohol abuse disorders: a common role for CREB and its target, the neuropeptide Y gene. | Pandey SC | β | 2003 | β |
| Blood alcohol concentrations after scheduled access in high-alcohol-preferring mice. | Grahame NJ et al. | β | 2003 | β |
| Confirmation of alcohol preference quantitative trait loci in the replicate high alcohol drinking and low alcohol drinking rat lines. | Foroud T et al. | β | 2003 | β |
| Differences in basal levels of CREB and NPY in nucleus accumbens regions between C57BL/6 and DBA/2 mice differing in inborn alcohol drinking behavior. | Misra K et al. | β | 2003 | β |
| Differential responding for brain stimulation reward and sucrose in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. | Woods JE et al. | β | 2003 | β |
| Effects of neuropeptide Y on sucrose and ethanol intake and on anxiety-like behavior in high alcohol drinking (HAD) and low alcohol drinking (LAD) rats. | Badia-Elder NE et al. | β | 2003 | β |
| High- and low-alcohol-preferring mice show differences in conditioned taste aversion to alcohol. | Chester JA et al. | β | 2003 | β |
| Minimal exposure to ethanol increases ethanol preference in Maudsley reactive male rats. | Adams N et al. | β | 2003 | β |
| Regional CNS densities of serotonin 1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pups. | Strother WN et al. | β | 2003 | β |
| Serotonin transporter gene variation is associated with alcohol sensitivity in rhesus macaques exposed to early-life stress. | Barr CS et al. | β | 2003 | β |
| Ethanol self-administration in Maudsley reactive and Maudsley nonreactive inbred rats. | Adams N et al. | β | 2002 | β |
| Neurobiology of relapse to alcohol in rats. | LΓͺ A et al. | β | 2002 | β |
| Neurophysiological profiles of replicate line 2 high-alcohol-drinking (HAD-2) and low-alcohol-drinking (LAD-2) rats. | Katner SN et al. | β | 2002 | β |
| The Fawn-Hooded (FH/Wjd) rat: a genetic animal model of comorbid depression and alcoholism. | Rezvani AH et al. | β | 2002 | β |
| The Maudsley Reactive and Nonreactive strains: a new perspective. | Blizard DA et al. | β | 2002 | β |
| Alcohol place preference conditioning in high- and low-alcohol preferring selected lines of mice. | Grahame NJ et al. | β | 2001 | β |
| Ethanol preference in Maudsley and RXNRA recombinant inbred strains of rats. | Adams N et al. | β | 2001 | β |
| Finding paradigms for the future of alcoholism research: an interdisciplinary perspective. | Meyer RE | β | 2001 | β |
| Genetic selection for high and low alcohol consumption in a limited-access paradigm. | LΓͺ AD et al. | β | 2001 | β |
| LAD rats learn a three-key drug discrimination more rapidly and achieve a higher level of performance than HAD rats. | McMillan DE et al. | β | 2001 | β |
| Neurochemical characteristics associated with ethanol preference in selected alcohol-preferring and -nonpreferring rats: a quantitative microdialysis study. | Katner SN et al. | β | 2001 | β |
| Regional central nervous system densities of delta-opioid receptors in alcohol-preferring P, alcohol-nonpreferring NP, and unselected Wistar rats. | Strother WN et al. | β | 2001 | β |
| Reliability of individual differences in initial sensitivity and acute tolerance to nitrous oxide hypothermia. | Kaiyala KJ et al. | β | 2001 | β |
| A characterization of approach and avoidance learning in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. | Blankenship MR et al. | β | 2000 | β |
| Altered amygdalar CRF release and increased anxiety-like behavior in Sardinian alcohol-preferring rats: a microdialysis and behavioral study. | Richter RM et al. | β | 2000 | β |
| An assessment of novelty-seeking behavior in alcohol-preferring and nonpreferring rats. | Nowak KL et al. | β | 2000 | β |
| Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders. Part 2. | Schuckit MA | β | 2000 | β |
| Cryobiology of rat embryos I: determination of zygote membrane permeability coefficients for water and cryoprotectants, their activation energies, and the development of improved cryopreservation methods. | Pfaff RT et al. | β | 2000 | β |
| Environmental influences on the failure to drink in inbred rats with an ethanol preference. | Adams N et al. | β | 2000 | β |
| Ethanol-induced c-fos expression in catecholamine- and neuropeptide Y-producing neurons in rat brainstem. | Thiele TE et al. | β | 2000 | β |
| Evaluation of behavioral disinhibition in P/NP and HAD1/LAD1 rats. | Steinmetz JE et al. | β | 2000 | β |
| Genetics of the risk for alcoholism. | Schuckit MA | β | 2000 | β |
| Neurophysiological findings and drinking levels in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. | Slawecki CJ et al. | β | 2000 | β |
| Norepinephrine uptake sites in the locus coeruleus of rat lines selectively bred for high and low alcohol preference: a quantitative autoradiographic binding study using [3H]-tomoxetine. | Hwang BH et al. | β | 2000 | β |
| Relating acoustic startle reactivity and plasticity to alcohol consumption in male Wistar rats. | Sandbak T et al. | β | 2000 | β |
| Selected lines and inbred strains. Tools in the hunt for the genes involved in alcoholism. | Grahame NJ | β | 2000 | β |
| The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations. | Rodd-Henricks ZA et al. | β | 2000 | β |
| Differences in neurophysiological indices of associative learning in alcohol-preferring and nonpreferring rats. | Slawecki CJ et al. | β | 1999 | β |
| Innate differences of neuropeptide Y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference. | Hwang BH et al. | β | 1999 | β |
| Limited access alcohol drinking in high- and low-alcohol preferring selected lines of mice. | Grahame NJ et al. | β | 1999 | β |
| Nitrous oxide-induced hypothermia in the rat: acute and chronic tolerance. | Ramsay DS et al. | β | 1999 | β |
| Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha 6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study. | Schuckit MA et al. | β | 1999 | β |
| The quantitative determination of R- and S-salsolinol in the striatum and adrenal gland of rats selectively bred for disparate alcohol drinking. | Haber H et al. | β | 1999 | β |
| Voluntary ethanol drinking during the first three postnatal weeks in lines of rats selectively bred for divergent ethanol preference. | McKinzie DL et al. | β | 1999 | β |
| A quantitative trait locus for alcohol consumption in selectively bred rat lines. | Carr LG et al. | β | 1998 | β |
| Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: voluntary ethanol consumption. | Gehle VM et al. | β | 1998 | β |
| Comparison of alcohol-preferring and nonpreferring selectively bred rat lines. I. Ethanol initiation and limited access operant self-administration. | Samson HH et al. | β | 1998 | β |
| Comparison of the alcohol-preferring P rat to the Wistar rat in behavioral tests of impulsivity and anxiety. | McMillen BA et al. | β | 1998 | β |
| Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference. | McKinzie DL et al. | β | 1998 | β |
| Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats. | Lin RC et al. | β | 1998 | β |
| Ethanol consumption and resistance are inversely related to neuropeptide Y levels. | Thiele TE et al. | β | 1998 | β |
| Genetics of alcoholism: rapid development of a new high-ethanol-preferring (HEP) strain of female and male rats. | Myers RD et al. | β | 1998 | β |
| More vasopressin mRNA in the paraventricular hypothalamic nucleus of alcohol-preferring rats and high alcohol-drinking rats selectively bred for high alcohol preference. | Hwang BH et al. | β | 1998 | β |
| Neuropeptide Y levels in ethanol-naive alcohol-preferring and nonpreferring rats and in Wistar rats after ethanol exposure. | Ehlers CL et al. | β | 1998 | β |
| Quantitative autoradiography of mu-opioid receptors in the CNS of alcohol-naive alcohol-preferring P and -nonpreferring NP rats. | McBride WJ et al. | β | 1998 | β |
| Serotonin3 receptor antagonism of alcohol intake: effects of drinking conditions. | McKinzie DL et al. | β | 1998 | β |
| Statistical methods in genetic research on smoking. | Heath AC et al. | β | 1998 | β |
| The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions. | McKinzie DL et al. | β | 1998 | β |
| Y do we drink? | Tecott LH et al. | β | 1998 | β |
| Behavioral similarities and differences among alcohol-preferring and -nonpreferring rats: confirmation by factor analysis and extension to additional groups. | Overstreet DH et al. | β | 1997 | β |
| Ethanol and cocaine intake by rats selectively bred for oral opioid acceptance. | Carlson KR et al. | β | 1997 | β |
| Five generations of selective breeding for ultrasonic vocalization (USV) responses in N:NIH strain rats. | Brunelli SA et al. | β | 1997 | β |
| Odor of specific alcohol solutions selectively alters locomotor activity of alcohol-drinking P rats. | Myers RD et al. | β | 1997 | β |
| Quantitative Autoradiography on [(35)S]TBPS Binding Sites of Gamma- Aminobutyric Acid(A) Receptors in Discrete Brain Regions of High- Alcohol-Drinking and Low-Alcohol- Drinking Rats Selectively Bred forHigh- and Low-Alcohol Preference. | Hwang BH et al. | β | 1997 | β |
| Regional CNS densities of monoamine receptors in alcohol-naive alcohol-preferring P and -nonpreferring NP rats. | McBride WJ et al. | β | 1997 | β |
| Regional CNS densities of serotonin and dopamine receptors in high alcohol-drinking (HAD) and low alcohol-drinking (LAD) rats. | McBride WJ et al. | β | 1997 | β |
| The neurobiology of alcoholism in genetically selected rat models. | Stewart RB et al. | β | 1997 | β |
| The Self-Rating of the Effects of alcohol (SRE) form as a retrospective measure of the risk for alcoholism. | Schuckit MA et al. | β | 1997 | β |
| Thyrotropin releasing hormone analog TA-0910 suppresses alcohol intake in alcohol drinking African green monkeys. | Rezvani AH et al. | β | 1997 | β |
| Characterization of a new hereditary thrombopathy in a closed colony of Wistar rats. | Smith SV et al. | β | 1996 | β |
| Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD rat lines. | McKinzie DL et al. | β | 1996 | β |
| High and low drinking rat lines: contributions to current understanding and future development. | Sinclair JD | β | 1996 | β |
| Isoflavonoid compounds extracted from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism. | Lin RC et al. | β | 1996 | β |
| Methodological issues in psychopathology research. | Sher KJ et al. | β | 1996 | β |
| Oral intake of sweetened or sweetened alcoholic beverages and open-field behavior. | Nadal RA et al. | β | 1996 | β |
| The biological, social and clinical bases of drug addiction: commentary and debate. | Altman J et al. | β | 1996 | β |
| Association between low contents of dopamine and serotonin in the nucleus accumbens and high alcohol preference. | McBride WJ et al. | β | 1995 | β |
| Classical and neoclassical approaches to the genetic analysis of alcohol-related phenotypes. | Dudek BC et al. | β | 1995 | β |
| Differential effects of nicotine in inbred and selectively bred rodents. | Overstreet DH | β | 1995 | β |
| Saccharin-induced increase in daily fluid intake as a predictor of voluntary alcohol intake in alcohol-preferring rats. | Kampov-Polevoy AB et al. | β | 1995 | β |
| Suppression of ethanol intake in alcohol-preferring rats by prior voluntary saccharin consumption. | Kampov-Polevoy AB et al. | β | 1995 | β |
| To drink or not to drink: open field behavior in alcohol-preferring and-nonpreferring rat strains. | Badishtov BA et al. | β | 1995 | β |
| To drink or not to drink: tests of anxiety and immobility in alcohol-preferring and alcohol-nonpreferring rat strains. | Viglinskaya IV et al. | β | 1995 | β |
| Alcohol sensitivity and dependence. | Schuckit MA | β | 1994 | β |
| Comparison of innate EEG parameters in rat lines selected for ethanol preference. | Morzorati S et al. | β | 1994 | β |
| Dietary salt and voluntary ethanol consumption in golden hamsters. | DiBattista D | β | 1994 | β |
| Genetic animal models of alcohol and drug abuse. | Crabbe JC et al. | β | 1994 | β |
| Genetic Aspects of Alcohol Use and Alcoholism in Women. | Svikis DS et al. | β | 1994 | β |
| Genetics of alcoholism: simultaneous presentation of a chocolate drink diminishes alcohol preference in high drinking HAD rats. | Lankford MF et al. | β | 1994 | β |
| Increased alcohol intake in low alcohol drinking rats after chronic infusion of the beta-carboline harman into the hippocampus. | Adell A et al. | β | 1994 | β |
| Initiation and maintenance of oral ethanol self-administration in female Sprague-Dawley rats. | Neill JC et al. | β | 1994 | β |
| Suppression of alcohol consumption by fenfluramine in Fawn-Hooded rats with serotonin dysfunction. | Rezvani AH et al. | β | 1994 | β |