The worldwide epidemiology of type 2 diabetes mellitus--present and future perspectives.
paper
Cited
Public
Unavailable
- Authors
- Chen, Lei; Magliano, Dianna J; Zimmet, Paul Z
- Year
- 2011
- Journal
- Nature reviews. Endocrinology
- PMID
- 22064493
- DOI
- 10.1038/nrendo.2011.183
Over the past three decades, the number of people with diabetes mellitus has more than doubled globally, making it one of the most important public health challenges to all nations. Type 2 diabetes mellitus (T2DM) and prediabetes are increasingly observed among children, adolescents and younger adults. The causes of the epidemic of T2DM are embedded in a very complex group of genetic and epigenetic systems interacting within an equally complex societal framework that determines behavior and environmental influences. This complexity is reflected in the diverse topics discussed in this Review. In the past few years considerable emphasis has been placed on the effect of the intrauterine environment in the epidemic of T2DM, particularly in the early onset of T2DM and obesity. Prevention of T2DM is a 'whole-of-life' task and requires an integrated approach operating from the origin of the disease. Future research is necessary to better understand the potential role of remaining factors, such as genetic predisposition and maternal environment, to help shape prevention programs. The potential effect on global diabetes surveillance of using HbA(1c) rather than glucose values in the diagnosis of T2DM is also discussed.
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External
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| Persimmon highly galloylated-tannins in vitro mitigated Ξ±-amylase and Ξ±-glucosidase via statically binding with their catalytic-closed sides and altering their secondary structure elements. | Zhu W et al. | β | 2020 | β |
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| Risk of severe maternal morbidity or death in relation to elevated hemoglobin A1c preconception, and in early pregnancy: AΒ population-based cohort study. | Davidson AJF et al. | β | 2020 | β |
| Sangguayin preparation prevents palmitate-induced apoptosis by suppressing endoplasmic reticulum stress and autophagy in db/db mice and MIN6 pancreatic Ξ²-cells. | Xing QC et al. | β | 2020 | β |
| Serum concentration of asprosin in new-onset type 2 diabetes. | Naiemian S et al. | β | 2020 | β |
| Serum cytokine dependent hematopoietic cell linker (CLNK) as a predictor for the duration of illness in type 2 diabetes mellitus. | Al-Fadhel SZ et al. | β | 2020 | β |
| Severe pulmonary radiological manifestations are associated with a distinct biochemical profile in blood of tuberculosis patients with dysglycemia. | Barreda NN et al. | β | 2020 | β |
| Shared (epi)genomic background connecting neurodegenerative diseases and type 2 diabetes. | Caputo V et al. | β | 2020 | β |
| Shifting the Care of Type 2 Diabetes Mellitus from Hospital to Primary Health Care Institutions through an Educational Intervention for Health Care Professionals: An Example from Rural China. | Chen S et al. | β | 2020 | β |
| Shorea roxburghii Leaf Extract Ameliorates Hyperglycemia Induced Abnormalities in High Fat/Fructose and Streptozotocin Induced Diabetic Rats. | Zhang W et al. | β | 2020 | β |
| Silencing of KCNQ1OT1 Decreases Oxidative Stress and Pyroptosis of Renal Tubular Epithelial Cells. | Zhu B et al. | β | 2020 | β |
| Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications. | Chang S et al. | β | 2020 | β |
| The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland. | Overvad M et al. | β | 2020 | β |
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| The prevalence of undiagnosed Prediabetes/type 2 diabetes, prehypertension/hypertension and obesity among ethnic groups of adolescents in Western Canada. | Spurr S et al. | β | 2020 | β |
| The Role of JNk Signaling Pathway in Obesityο»Ώ-Driven Insulin Resistance. | Feng J et al. | β | 2020 | β |
| The Role of Offspring Genotype-By-Sex Interactions, Independently of Environmental Cues, on the Phenotype Traits of an Obese Swine Model. | Heras-Molina A et al. | β | 2020 | β |
| Treatment of Diabetic Neuropathy with A Novel PAR1-Targeting Molecule. | Shavit-Stein E et al. | β | 2020 | β |
| Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention. | Liu J et al. | β | 2020 | β |
| Type 1 and type 2 diabetes after gestational diabetes: a 23Β year cohort study. | Auvinen AM et al. | β | 2020 | β |
| Ultrasonographic Renal Dimensions Amongst Adult Nigerian Diabetics: Correlation with Clinical, Anthropometric and Metabolic Risk Factors. | Assenyi SS et al. | β | 2020 | β |
| Using Intervention Mapping to Develop a Digital Self-Management Program for People With Type 2 Diabetes: Tutorial on MyDESMOND. | Hadjiconstantinou M et al. | β | 2020 | β |
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| Zinc, copper, and oxysterol levels in patients with type 1 and type 2 diabetes mellitus. | Samadi A et al. | β | 2020 | β |
| A 12-week pilot study of acceptance of a computer-based chronic disease self-monitoring system among patients with type 2 diabetes mellitus and/or hypertension. | Yan M et al. | β | 2019 | β |
| A comparative evaluation of medicine package inserts for oral antidiabetic agents in Palestine. | Eshtayeh M et al. | β | 2019 | β |
| A Depiction of Rehabilitation Patients 65 Years and Younger With Dysvascular Lower Extremity Amputation. | Mayo AL et al. | β | 2019 | β |
| Aging, the menopausal transition, and hormone replenishment therapy: retrieval of confidence and compliance. | Saul SR et al. | β | 2019 | β |
| Amelioration of dry eye syndrome in db/db mice with diabetes mellitus by treatment with Tibetan Medicine Formula Jikan Mingmu Drops. | Ai X et al. | β | 2019 | β |
| A Mendelian Randomization Study on Infant Length and Type 2 Diabetes Mellitus Risk. | Zhuang H et al. | β | 2019 | β |
| Anthropometric, Cardiopulmonary and Metabolic Benefits of the High-Intensity Interval Training Versus Moderate, Low-Intensity or Control for Type 2 Diabetes: Systematic Review and Meta-Analysis. | Lora-Pozo I et al. | β | 2019 | β |
| A predictive analytics framework for identifying patients at risk of developing multiple medical complications caused by chronic diseases. | Talaei-Khoei A et al. | β | 2019 | β |
| A review of the putative causal mechanisms associated with lower macular pigment in diabetes mellitus. | Scanlon G et al. | β | 2019 | β |
| A review on diabetic foot challenges in Guyanese perspective. | Kurup R et al. | β | 2019 | β |
| Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets. | Huang M et al. | β | 2019 | β |
| Assessment of liver marker enzymes and its association with type 2 diabetes mellitus in Northwest Ethiopia. | Shibabaw T et al. | β | 2019 | β |
| Association between air pollution and type 2 diabetes: an updated review of the literature. | Li Y et al. | β | 2019 | β |
| Association Between Pioglitazone Use and Prostate Cancer: A Population-Based Case-Control Study in the Han Population. | Kao LT et al. | β | 2019 | β |
| Association of fatty liver index with risk of incident type 2 diabetes by metabolic syndrome status in an Eastern Finland male cohort: a prospective study. | Olubamwo OO et al. | β | 2019 | β |
| Association of pupil responses with severity of erectile dysfunction in diabetes mellitus. | Cankurtaran V et al. | β | 2019 | β |
| Associations between the built environment and body mass index in the Mexican American Mano A Mano Cohort. | Zhang X et al. | β | 2019 | β |
| Biophysical modeling of Ξ²-cells networks: Realistic architectures and heterogeneity effects. | Loppini A et al. | β | 2019 | β |
| Canagliflozin and Stroke in Type 2 Diabetes Mellitus. | Zhou Z et al. | β | 2019 | β |
| Capsaicin Analogues Derived from <i>n</i>-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by Ξ²-Cells In Vitro. | Cione E et al. | β | 2019 | β |
| Care providers' perceptions towards challenges and opportunities for service improvement at diabetes management clinics in public primary health care in Muscat, Oman: a qualitative study. | Al-Alawi K et al. | β | 2019 | β |
| Cerium Oxide Nanoparticles Regulate Insulin Sensitivity and Oxidative Markers in 3T3-L1 Adipocytes and C2C12 Myotubes. | Lopez-Pascual A et al. | β | 2019 | β |
| Clinical significance of long noncoding RNA VIM-AS1 and CTBP1-AS2 expression in type 2 diabetes. | Erfanian Omidvar M et al. | β | 2019 | β |
| Common, but not easy. | Pimlott N | β | 2019 | β |
| Comparison of persistence and adherence between fixed-dose combinations and two-pill combinations in Japanese patients with type 2 diabetes. | Nishimura R et al. | β | 2019 | β |
| Cost-effectiveness of first-line versus delayed use of combination dapagliflozin and metformin in patients with type 2 diabetes. | Chin KL et al. | β | 2019 | β |
| Could the high consumption of high glycaemic index carbohydrates and sugars, associated with the nutritional transition to the Western type of diet, be the common cause of the obesity epidemic and the worldwide increasing incidences of Type 1 and Type 2 diabetes? | SjΓΆblad S | β | 2019 | β |
| C-reactive protein for predicting cardiovascular and all-cause mortality in type 2 diabetic patients: A meta-analysis. | Tian R et al. | β | 2019 | β |
| Design and synthesis of rosiglitazone-ferulic acid-nitric oxide donor trihybrids for improving glucose tolerance. | Liu J et al. | β | 2019 | β |
| Diabetes Comorbidity Increases Risk of Postoperative Complications in Traumatic Thoracic Vertebral Fracture Repair: A Propensity Score Matched Analysis. | Loewenstern J et al. | β | 2019 | β |
| Diabetes fatalism and its emotional distress subscale are independent predictors of glycemic control among Lebanese patients with type 2 diabetes. | Sukkarieh-Haraty O et al. | β | 2019 | β |
| Diabetes Mellitus among Adult Tuberculosis Patients Attending Tuberculosis Clinics in Eastern Ethiopia. | Tenaye L et al. | β | 2019 | β |
| Diabetic Cardiomyopathy Modelling Using Induced Pluripotent Stem Cell Derived Cardiomyocytes: Recent Advances and Emerging Models. | GranΓ©li C et al. | β | 2019 | β |
| Differences in health behaviors and health outcomes among non-Hispanic Whites and Arab Americans in a population-based survey in California. | Abuelezam NN et al. | β | 2019 | β |
| Different metabolic/obesity phenotypes are differentially associated with development of prediabetes in adults: Results from a 14-year cohort study. | Haghighatdoost F et al. | β | 2019 | β |
| E-cadherin and periostin in early detection and progression of diabetic nephropathy: epithelial-to-mesenchymal transition. | El-Dawla NMQ et al. | β | 2019 | β |
| Effectiveness of royal jelly supplementation in glycemic regulation: A systematic review. | Omer K et al. | β | 2019 | β |
| Effects of exercise training on type 2-diabetes: the role of Meteorin-like protein. | Saeidi A et al. | β | 2019 | β |
| Effects of Gender-Affirming Hormones on Lipid, Metabolic, and Cardiac Surrogate Blood Markers in Transgender Persons. | Defreyne J et al. | β | 2019 | β |
| Effects of Genetic Variants of Nuclear Receptor Y on the Risk of Type 2 Diabetes Mellitus. | Wang Y et al. | β | 2019 | β |
| Effects of Lifestyle Modification and Anti-diabetic Medicine on Prediabetes Progress: A Systematic Review and Meta-Analysis. | Sheng Z et al. | β | 2019 | β |
| Efficacy and hypoglycemic risk of sitagliptin in obese/overweight patients with type 2 diabetes compared with GLP-1 receptor agonists: A meta-analysis. | Dai D et al. | β | 2019 | β |
| Efficacy and safety of berberine in the treatment of type 2 diabetes with insulin resistance: Protocol for a systematic review. | Wang Y et al. | β | 2019 | β |
| Efficacy of adjunctive photodynamic therapy on the clinical periodontal, HbA1c and advanced glycation end product levels among mild to moderate chronic periodontal disease patients with type 2 diabetes mellitus: A randomized controlled clinical trial. | Mirza S et al. | β | 2019 | β |
| Epicardial fat tissue in patients with diabetes mellitus: a systematic review and meta-analysis. | Li Y et al. | β | 2019 | β |
| Evaluation of Serum microRNAs in Patients with Diabetic Kidney Disease: A Nested Case-Controlled Study and Bioinformatics Analysis. | Regmi A et al. | β | 2019 | β |
| Exploring the role of competing demands and routines during the implementation of a self-management tool for type 2 diabetes: a theory-based qualitative interview study. | Potthoff S et al. | β | 2019 | β |
| Factors associated with physicians' decision to discontinue or down-titrate sulfonylureas for type 2 diabetes patients. | Laires P et al. | β | 2019 | β |
| Factors influencing diabetes self-care practice among type 2 diabetes patients attending diabetic care follow up at an Ethiopian General Hospital, 2018. | Tiruneh SA et al. | β | 2019 | β |
| Factors influencing diet barriers among outpatients with poorly-controlled type 2 diabetes: A descriptive correlational study. | Cheng LJ et al. | β | 2019 | β |
| Fine-tuning of microRNAs in Type 2 Diabetes Mellitus. | Rosado JA et al. | β | 2019 | β |
| Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels. | Al-Ishaq RK et al. | β | 2019 | β |
| Genetic Associations With Diabetic Retinopathy and Coronary Artery Disease in Emirati Patients With Type-2 Diabetes Mellitus. | Azzam SK et al. | β | 2019 | β |
| Genetic risk score combining six genetic variants associated with the cellular NRF2 expression levels correlates with Type 2 diabetes in the human population. | Shin JH et al. | β | 2019 | β |
| Genetic Variation of Physicochemical Properties and Digestibility of Foxtail Millet (<i>Setaria italica</i>) Landraces of Taiwan. | Yin SY et al. | β | 2019 | β |
| Glucose-6 Phosphate, A Central Hub for Liver Carbohydrate Metabolism. | Rajas F et al. | β | 2019 | β |
| HbA1c showed a positive association with carcinoembryonic antigen (CEA) level in only diabetes, not prediabetic or normal individuals. | Chung S et al. | β | 2019 | β |
| Health literacy, knowledge and self-care behaviors to take care of diabetic foot in low-income individuals: Application of extended parallel process model. | Lael-Monfared E et al. | β | 2019 | β |
| Hepatic stress associated with pathologies characterized by disturbed glucose production. | Gjorgjieva M et al. | β | 2019 | β |
| Histone deacetylases in cardiovascular and metabolic diseases. | Bagchi RA et al. | β | 2019 | β |
| Human tissue inhibitor of metalloproteinases-1 improved wound healing in diabetes through its anti-apoptotic effect. | Lao G et al. | β | 2019 | β |
| Hyper-reflective foci segmentation in SD-OCT retinal images with diabetic retinopathy using deep convolutional neural networks. | Yu C et al. | β | 2019 | β |
| <i>Astragalus</i> alters gut-microbiota composition in type 2 diabetes mice: clues to its pharmacology. | Li XY et al. | β | 2019 | β |
| Identification of a Novel Scaffold for Inhibition of Dipeptidyl Peptidase-4. | Mishra A et al. | β | 2019 | β |
| "I have got diabetes!" - interviews of patients newly diagnosed with type 2 diabetes. | Pikkemaat M et al. | β | 2019 | β |
| Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. | O'Connor S et al. | β | 2019 | β |
| Increasing burden of type 2 diabetes in Navajo youth: The SEARCH for diabetes in youth study. | Powell J et al. | β | 2019 | β |
| Insulin-like growth factor axis in pregnancy and gestational diabetes mellitus. | AnderlovΓ‘ K et al. | β | 2019 | β |
| Levels of personality functioning and not depression predict decline of plasma glucose concentration in patients with type 2 diabetes mellitus. | Ehrenthal JC et al. | β | 2019 | β |
| Mechanisms Involved in Glycemic Control Promoted by Exercise in Diabetics. | Andrade EF et al. | β | 2019 | β |
| Medically Tailored Meals as a Prescription for Treatment of Food-Insecure Type 2 Diabetics. | Rabaut LJ | β | 2019 | β |
| Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway. | Niu C et al. | β | 2019 | β |
| Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. | Driessen JHM et al. | β | 2019 | β |
| Mother or Father: Who Is in the Front Line? Mechanisms Underlying the Non-Genomic Transmission of Obesity/Diabetes via the Maternal or the Paternal Line. | Portha B et al. | β | 2019 | β |
| Neuroimaging endophenotypes of type 2 diabetes mellitus: a discordant sibling pair study. | Zhang D et al. | β | 2019 | β |
| Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice. | Guo J et al. | β | 2019 | β |
| Overview of genomics and post-genomics research on type 2 diabetes mellitus: Future perspectives and a framework for further studies. | Reddy BM et al. | β | 2019 | β |
| Postpartum Circulating Cell-Free Insulin DNA Levels Are Higher in Women with Previous Gestational Diabetes Mellitus Who Develop Type 2 Diabetes in Later Life. | Lappas M et al. | β | 2019 | β |
| PPARG Polymorphisms Are Associated with Unexplained Mild Vision Loss in Patients with Type 2 Diabetes Mellitus. | Li T et al. | β | 2019 | β |
| Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system. | Zou X et al. | β | 2019 | β |
| Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta-analysis of comparative and epidemiological studies. | Wang F et al. | β | 2019 | β |
| Prevalence of postprandial hyperglycaemia in basal insulin-treated patients with type 2 diabetes mellitus with controlled fasting glycaemia and elevated glycosylated haemoglobin. | Tinahones FJ et al. | β | 2019 | β |
| Prevalence of type 2 diabetes among adolescents in Brazil: Findings from Study of Cardiovascular Risk in Adolescents (ERICA). | Telo GH et al. | β | 2019 | β |
| Prevention and screening recommendations in type 2 diabetes: Review and critical appraisal of clinical practice guidelines. | Diab M et al. | β | 2019 | β |
| Procyanidin A2, an anti-diabetic condensed tannin extracted from <i>Wendlandia glabrata</i>, reduces elevated G-6-Pase and mRNA levels in diabetic mice and increases glucose uptake in CC1 hepatocytes and C1C12 myoblast cells. | Sheikh Y et al. | β | 2019 | β |
| Quantitative gingival crevicular fluid proteome in type 2 diabetes mellitus and chronic periodontitis. | Marinho MC et al. | β | 2019 | β |
| Relation of Diabetes to Cognitive Function in Hispanics/Latinos of Diverse Backgrounds in the United States. | Elfassy T et al. | β | 2019 | β |
| Relationship between natural killer cell activity and glucose control in patients with typeΒ 2 diabetes and prediabetes. | Kim JH et al. | β | 2019 | β |
| Restoration of insulin receptor improves diabetic phenotype in T2DM mice. | Wang Y et al. | β | 2019 | β |
| Retinal Microvascular Abnormalities in Children with Type 1 Diabetes Mellitus Without Visual Impairment or Diabetic Retinopathy. | Li T et al. | β | 2019 | β |
| Risk of type 2 diabetes in metabolically healthy people in different categories of body mass index: an updated network meta-analysis of prospective cohort studies. | Tajik S et al. | β | 2019 | β |
| Role of exercise-induced hepatokines in metabolic disorders. | Ennequin G et al. | β | 2019 | β |
| Selenium and iodine in diabetes mellitus with a focus on the interplay and speciation of the elements. | Solovyev N et al. | β | 2019 | β |
| Serum high-density lipoprotein cholesterol is a protective predictor of executive function in older patients with diabetes mellitus. | Sun Y et al. | β | 2019 | β |
| Severity of depression, anxious distress and the risk of type 2 diabetes - a population-based cohort study in Sweden. | Deleskog A et al. | β | 2019 | β |
| Sex-based differences in hepatic and skeletal muscle triglyceride storage and metabolism <sup>1</sup>. | Beaudry KM et al. | β | 2019 | β |
| SPION-Decorated Exosome Delivered BAY55-9837 Targeting the Pancreas through Magnetism to Improve the Blood GLC Response. | Zhuang M et al. | β | 2019 | β |
| Sulforaphane Prevents Hepatic Insulin Resistance by Blocking Serine Palmitoyltransferase 3-Mediated Ceramide Biosynthesis. | Teng W et al. | β | 2019 | β |
| Sustained Release Strategy Designed for Lixisenatide Delivery to Synchronously Treat Diabetes and Associated Complications. | Zhuang Y et al. | β | 2019 | β |
| The -44 C/G (rs1800972) polymorphism of the Ξ²-defensin 1 is associated with increased risk of developing type 2 diabetes mellitus. | Martinez-Rios MA et al. | β | 2019 | β |
| The Action of Polyphenols in Diabetes Mellitus and Alzheimer's Disease: A Common Agent for Overlapping Pathologies. | Silveira AC et al. | β | 2019 | β |
| The effectiveness of yoga to prevent diabetes mellitus type 2: A protocol for systematic review and meta-analysis. | Ramamoorthi R et al. | β | 2019 | β |
| The effect of diabetes mellitus on pharmacokinetics, pharmacodynamics and adverse drug reactions of anticancer drugs. | Mashayekhi-Sardoo H et al. | β | 2019 | β |
| The effect of resveratrol supplementation on the expression levels of factors associated with cellular senescence and sCD163/sTWEAK ratio in patients with type 2 diabetes mellitus: study protocol for a double-blind controlled randomised clinical trial. | Abdollahi S et al. | β | 2019 | β |
| The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes. | Sharma M et al. | β | 2019 | β |
| The hefty fetal phenotype hypothesis revisited: high birth weight, type 2 diabetes and gestational diabetes in a Saskatchewan cohort of First Nations and non-First Nations women. | Dyck RF et al. | β | 2019 | β |
| The Impact of DJOS Surgery, a High Fat Diet and a Control Diet on the Enzymes of Glucose Metabolism in the Liver and Muscles of Sprague-Dawley Rats. | Stygar D et al. | β | 2019 | β |
| The protective role of the MKP-5-JNK/P38 pathway in glucolipotoxicity-induced islet Ξ²-cell dysfunction and apoptosis. | Song Z et al. | β | 2019 | β |
| The role of microRNAs in the healing of diabetic ulcers. | Goodarzi G et al. | β | 2019 | β |
| The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers. | Saravanan MS et al. | β | 2019 | β |
| The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders. | Kraeuter AK et al. | β | 2019 | β |
| TNF-Ξ± (-308) Gene Polymorphism and Type 2 Diabetes Mellitus in Ethiopian Diabetes Patients. | Ayelign B et al. | β | 2019 | β |
| Using data from online geocoding services for the assessment of environmental obesogenic factors: a feasibility study. | PrΓ€ger M et al. | β | 2019 | β |
| Using patient reported outcomes in diabetes research and practice: Recommendations from a national workshop. | Marrero DG et al. | β | 2019 | β |
| Vagal Nerve Stimulation for Glycemic Control in a Rodent Model of Type 2 Diabetes. | Yin J et al. | β | 2019 | β |
| Vitamin D3 as adjuvant in the treatment of type 2 diabetes mellitus: modulation of genomic and biochemical instability. | Fagundes GE et al. | β | 2019 | β |
| Vitamin D Increases Glucose Stimulated Insulin Secretion from Insulin Producing Beta Cells (INS1E). | Bornstedt ME et al. | β | 2019 | β |
| Wedtrilosides A and B, two new diterpenoid glycosides from the leaves of Wedelia trilobata (L.) Hitchc. with Ξ±-amylase and Ξ±-glucosidase inhibitory activities. | Luyen NT et al. | β | 2019 | β |
| Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis. | Wang T et al. | β | 2018 | β |
| Achievement of guideline targets for blood pressure, lipid, and glycaemic control in type 2 diabetes: A meta-analysis. | Khunti K et al. | β | 2018 | β |
| A Descriptive Review of the Prevalence and Usage of Traditional and Complementary Medicine among Saudi Diabetic Patients. | Alsanad S et al. | β | 2018 | β |
| A group-based lifestyle intervention for diabetes prevention in low- and middle-income country: implementation evaluation of the Kerala Diabetes Prevention Program. | Aziz Z et al. | β | 2018 | β |
| Ambient air pollution in relation to diabetes and glucose-homoeostasis markers in China: a cross-sectional study with findings from the 33 Communities Chinese Health Study. | Yang BY et al. | β | 2018 | β |
| Ameliorative effects of bee pollen and date palm pollen on the glycemic state and male sexual dysfunctions in streptozotocin-Induced diabetic wistar rats. | Mohamed NA et al. | β | 2018 | β |
| A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone. | JΓΆnsson TJ et al. | β | 2018 | β |
| An overview of type 2 diabetes and importance of vitamin D3-vitamin D receptor interaction in pancreatic Ξ²-cells. | Neelankal John A et al. | β | 2018 | β |
| Antidiabetic Effects of a Chinese Herbal Medicinal Compound Sangguayin Preparation via PI3K/Akt Signaling Pathway in <i>db/db</i> Mice. | Xing Q et al. | β | 2018 | β |
| Antioxidant properties of drugs used in Type 2 diabetes management: could they contribute to, confound or conceal effects of antioxidant therapy? | Choi SW et al. | β | 2018 | β |
| Apo-12'-lycopenal, a Lycopene Metabolite, Promotes Adipocyte Differentiation via Peroxisome Proliferator-Activated Receptor Ξ³ Activation. | Takahashi S et al. | β | 2018 | β |
| Appropriateness of Using Tests for Blood Glucose and Diabetic Complications in Clinical Practice: Experiences in a Hospital in Thailand. | Lekskulchai V | β | 2018 | β |
| Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose-lowering therapy. | Mahdi A et al. | β | 2018 | β |
| Association of type 2 diabetes susceptible genes GCKR, SLC30A8, and FTO polymorphisms with gestational diabetes mellitus risk: a meta-analysis. | Lin Z et al. | β | 2018 | β |
| Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Type 2 Diabetes Mellitus. | Wang Y et al. | β | 2018 | β |
| Asymmetric dimethylarginine and soluble inter-cellular adhesion molecule-1 serum levels alteration following ginger supplementation in patients with type 2 diabetes: a randomized double-blind, placebo-controlled clinical trial. | Zarezadeh M et al. | β | 2018 | β |
| Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice. | Parthsarathy V et al. | β | 2018 | β |
| Carbohydrate Replacement of Rice or Potato with Lentils Reduces the Postprandial Glycemic Response in Healthy Adults in an Acute, Randomized, Crossover Trial. | Moravek D et al. | β | 2018 | β |
| Celastrol antagonizes high glucose-evoked podocyte injury, inflammation and insulin resistance by restoring the HO-1-mediated autophagy pathway. | Zhan X et al. | β | 2018 | β |
| Change in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes. | Bjerregaard LG et al. | β | 2018 | β |
| Characteristics of frequent emergency department users with type 2 diabetes mellitus in Korea. | Ustulin M et al. | β | 2018 | β |
| Characterization and hypoglycemic effect of a neutral polysaccharide extracted from the residue of Codonopsis Pilosula. | Liu W et al. | β | 2018 | β |
| Characterization of forced degradation products of canagliflozine by liquid chromatography/quadrupole time-of-flight tandem mass spectrometry and in silico toxicity predictions. | Baira SM et al. | β | 2018 | β |
| Childhood maltreatment and adult medical morbidity in mood disorders: comparison of unipolar depression with bipolar disorder. | Hosang GM et al. | β | 2018 | β |
| Cognitive deficits and Alzheimer-like neuropathological impairments during adolescence in a rat model of type 2 diabetes mellitus. | Jin L et al. | β | 2018 | β |
| Comparison of two low-fat diets, differing in protein and carbohydrate, on psychological wellbeing in adults with obesity and type 2 diabetes: a randomised clinical trial. | Watson NA et al. | β | 2018 | β |
| Cost-of-illness of type 2 diabetes mellitus in low and lower-middle income countries: a systematic review. | Afroz A et al. | β | 2018 | β |
| Curcumin-mediated effects on anti-diabetic drug-induced cardiotoxicity. | Jain A et al. | β | 2018 | β |
| Cyclodextrin-grafted poly(anhydride) nanoparticles for oral glibenclamide administration. In vivo evaluation using C. elegans. | Lucio D et al. | β | 2018 | β |
| Decreased serum microRNA-21 level is associated with obesity in healthy and type 2 diabetic subjects. | Ghorbani S et al. | β | 2018 | β |
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| Risk of cirrhosis-related complications in patients with advanced fibrosis following hepatitis C virus eradication. | van der Meer AJ et al. | β | 2017 | β |
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| The ACE2 G8790A Polymorphism: Involvement in Type 2 Diabetes Mellitus Combined with Cerebral Stroke. | Wu YH et al. | β | 2017 | β |
| The prevalence of type 2 diabetes in urban Bo, Sierra Leone, and in the 16 countries of the West Africa region. | Sundufu AJ et al. | β | 2017 | β |
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| The relationship between social capital components and control of type 2 diabetes: A path analysis model. | Moradi Y et al. | β | 2017 | β |
| Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway. | FangFang et al. | β | 2017 | β |
| Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study. | Bos MM et al. | β | 2017 | β |
| Total and subtypes of dietary fat intake and risk of type 2 diabetes mellitus in the PrevenciΓ³n con Dieta MediterrΓ‘nea (PREDIMED) study. | Guasch-FerrΓ© M et al. | β | 2017 | β |
| Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population. | Noh J et al. | β | 2017 | β |
| Validation of self-reported diabetes in a representative sample of SΓ£o Paulo city. | Fontanelli MM et al. | β | 2017 | β |
| Validity and Relative Ability of 4 Balance Tests to Identify Fall Status of Older Adults With Type 2 Diabetes. | Marques A et al. | β | 2017 | β |
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| Acetylation control of cardiac fatty acid Ξ²-oxidation and energy metabolism in obesity, diabetes, and heart failure. | Fukushima A et al. | β | 2016 | β |
| Activation of PI3KΞ³/Akt pathway increases cardiomyocyte HMGB1 expression in diabetic environment. | Song J et al. | β | 2016 | β |
| Addressing noncommunicable diseases in primary care: the case of type 2 diabetes. | Narayan KM et al. | β | 2016 | β |
| Anti-Inflammatory Effects of Rosiglitazone in Obesity-Impaired Wound Healing Depend on Adipocyte Differentiation. | Siebert A et al. | β | 2016 | β |
| Association between -308G/A TNFA Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Systematic Review. | Luna GI et al. | β | 2016 | β |
| Association between DPP4 gene polymorphism and serum lipid levels in Chinese type 2 diabetes individuals. | Xing X et al. | β | 2016 | β |
| Association between Serum Albumin Concentration and Ketosis Risk in Hospitalized Individuals with Type 2 Diabetes Mellitus. | Cheng PC et al. | β | 2016 | β |
| Association of HLA-A, B, DRB1* and DQB1* alleles and haplotypes in south Indian T2DM patients. | Chinniah R et al. | β | 2016 | β |
| Benzylglucosinolate Derived Isothiocyanate from Tropaeolum majus Reduces Gluconeogenic Gene and Protein Expression in Human Cells. | GuzmΓ‘n-PΓ©rez V et al. | β | 2016 | β |
| Can an early diagnostic procedure of metformin-associated lactic acidosis in an emergency unit reduce mortality? | SΓ©mely D et al. | β | 2016 | β |
| Cardiovascular and Metabolic Effects of AΓ§aΓ, an Amazon Plant. | de Moura RS et al. | β | 2016 | β |
| Clinical features of childhood diabetes mellitus focusing on latent autoimmune diabetes. | Lee SH et al. | β | 2016 | β |
| Comparing the mortality risks of nursing professionals with diabetes and general patients with diabetes: a nationwide matched cohort study. | Huang HL et al. | β | 2016 | β |
| Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis. | Zhao Z et al. | β | 2016 | β |
| Connecting PM2.5 Exposure to Insulin Resistance: Oxidative Stress May Be an Intermediate Step. | Barrett JR | β | 2016 | β |
| Critical roles of soluble starch synthase SSIIIa and granule-bound starch synthase Waxy in synthesizing resistant starch in rice. | Zhou H et al. | β | 2016 | β |
| Diagnosed but Not Undiagnosed Diabetes Is Associated with Depression in Rural Areas. | Li Z et al. | β | 2016 | β |
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| Dual Energy X-Ray Absorptiometry Compared with Anthropometry in Relation to Cardio-Metabolic Risk Factors in a Young Adult Population: Is the 'Gold Standard' Tarnished? | Demmer DL et al. | β | 2016 | β |
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| Establishment and Characterization of a Newly Established Diabetic Gerbil Line. | Li X et al. | β | 2016 | β |
| Evaluation of gastric blood supply in diabetic patients with gastroparesis by contrast-enhanced ultrasound. | Shen HL et al. | β | 2016 | β |
| Evaluation of patient-reported outcomes data in structured diabetes education intervention: 2-year follow-up data of patient empowerment programme. | Wong CK et al. | β | 2016 | β |
| Exercise and Beta-Glucan Consumption (Saccharomyces cerevisiae) Improve the Metabolic Profile and Reduce the Atherogenic Index in Type 2 Diabetic Rats (HFD/STZ). | Andrade EF et al. | β | 2016 | β |
| Exogenous hydrogen sulfide protects against high glucoseβinduced inflammation and cytotoxicity in H9c2 cardiac cells. | Huang Z et al. | β | 2016 | β |
| Factors that could explain the increasing prevalence of type 2 diabetes among adults in a Canadian province: a critical review and analysis. | Thibault V et al. | β | 2016 | β |
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| Genetic Variants of Retinoic Acid Receptor-Related Orphan Receptor Alpha Determine Susceptibility to Type 2 Diabetes Mellitus in Han Chinese. | Zhang Y et al. | β | 2016 | β |
| High Fructose Diet inducing diabetes rapidly impacts olfactory epithelium and behavior in mice. | RiviΓ¨re S et al. | β | 2016 | β |
| Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort. | Zhu Y et al. | β | 2016 | β |
| In vitro and in vivo anti-diabetic and hepatoprotective effects of edible pods of Parkia roxburghii and quantification of the active constituent by HPLC-PDA. | Sheikh Y et al. | β | 2016 | β |
| Islet-like organoids derived from human pluripotent stem cells efficiently function in the glucose responsiveness in vitro and in vivo. | Kim Y et al. | β | 2016 | β |
| Job Strain as a Risk Factor for Incident Diabetes Mellitus in Middle and Older Age U.S. Workers. | Mutambudzi M et al. | β | 2016 | β |
| MECHANISMS IN ENDOCRINOLOGY: Parity and risk of type 2 diabetes: a systematic review and dose-response meta-analysis. | Li P et al. | β | 2016 | β |
| Meta-analysis of the association between four CAPN10 gene variants and gestational diabetes mellitus. | Cui J et al. | β | 2016 | β |
| Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice. | Yu JW et al. | β | 2016 | β |
| Parity and type 2 diabetes mellitus: a study of insulin resistance and Ξ²-cell function in women with multiple pregnancies. | Iversen DS et al. | β | 2016 | β |
| Pioglitazone increases the glycolytic efficiency of human Sertoli cells with possible implications for spermatogenesis. | Meneses MJ et al. | β | 2016 | β |
| Postpartum IGF-I and IGFBP-2 levels are prospectively associated with the development of type 2 diabetes in women with previous gestational diabetes mellitus. | Lappas M et al. | β | 2016 | β |
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| Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis. | Telo GH et al. | β | 2016 | β |
| Prognosis of Ischemic Stroke With Newly Diagnosed Diabetes Mellitus According to Hemoglobin A1c Criteria in Chinese Population. | Jing J et al. | β | 2016 | β |
| Real-world evidence studies into treatment adherence, thresholds for intervention and disparities in treatment in people with type 2 diabetes in the UK. | McGovern A et al. | β | 2016 | β |
| Recent advances in the development of protein tyrosine phosphatase 1B inhibitors for Type 2 diabetes. | Qian S et al. | β | 2016 | β |
| Regulatory Roles of MicroRNAs in Diabetes. | Feng J et al. | β | 2016 | β |
| Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice. | Bankoglu EE et al. | β | 2016 | β |
| Status of stem cells in diabetic nephropathy: predictive and preventive potentials. | Baban B et al. | β | 2016 | β |
| Transcultural Endocrinology: Adapting Type-2 Diabetes Guidelines on a Global Scale. | Nieto-MartΓnez R et al. | β | 2016 | β |
| Type 2 diabetes mellitus and risk of colorectal adenoma: a meta-analysis of observational studies. | Yu F et al. | β | 2016 | β |
| Validation and psychometric evaluation of physical activity belief scale among patients with type 2 diabetes mellitus: an application of health action process approach. | Rohani H et al. | β | 2016 | β |