Comparison of the action of baclofen with gamma-aminobutyric acid on rat hippocampal pyramidal cells in vitro.
paper
Cited
Public
Unavailable
- Authors
- Newberry, N R; Nicoll, R A
- Year
- 1985
- Journal
- The Journal of physiology
- PMID
- 3989713
- DOI
- 10.1113/jphysiol.1985.sp015610
- PMCID
- PMC1193454
Intracellular recordings from CA1 pyramidal cells in the hippocampal slice preparation were used to compare the action of baclofen, a gamma-aminobutyric acid (GABA) analogue, with GABA. Ionophoretic application of GABA or baclofen into stratum (s.) pyramidale evoked hyperpolarizations associated with reductions in the input resistance of the cell. Baclofen responses were easier to elicit in the dendrites than in the cell body layer. Blockade of synaptic transmission, with tetrodotoxin or cadmium, did not reduce baclofen responses, indicating a direct post-synaptic action. (+)-Bicuculline (10 microM) and bicuculline methiodide (100 microM) had little effect on baclofen responses but strongly antagonized somatic GABA responses of equal amplitude. The bicuculline resistance of the baclofen response was not absolute, as higher concentrations of these compounds did reduce it. Pentobarbitone (100 microM) enhanced somatic GABA responses without affecting baclofen responses. (-)-Baclofen was approximately 200 times more potent than (+)-baclofen. The reversal potentials for the somatic GABA and baclofen responses were -70 mV and -85 mV respectively. When the membrane was depolarized, the baclofen response was reduced. This apparent voltage sensitivity was not seen with somatic GABA responses. Altering the chloride gradient across the cell membrane altered the reversal potential of the somatic GABA response but not that of the baclofen response. It was extrapolated that a tenfold shift in the extracellular potassium concentration would cause a 48 mV shift in the reversal potential of the baclofen response. Barium ions reduced the baclofen response, but not the GABA response. Orthodromic stimulation produced a fast inhibitory post-synaptic potential (i.p.s.p.) and a slow i.p.s.p. The properties of the fast and slow i.p.s.p.s were remarkably similar to those of the somatic GABA and baclofen responses, respectively. Application of GABA to the pyramidal cell dendrites evoked, in addition to a depolarization, two types of hyperpolarization. One type of hyperpolarization was bicuculline sensitive, had a reversal potential of about -65 mV and appeared to be chloride dependent. The other hyperpolarization was more easily observed in bicuculline methiodide (100 microM). This response was similar to that evoked by baclofen since it had a high reversal potential (about -90 mV), was relatively insensitive to changes in the chloride gradient across the cell membrane and was reduced by barium. The bicuculline-sensitive hyperpolarization could be evoked by the dendritic or somatic ionophoresis of muscimol and THIP (4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3(2H)-one.(ABSTRACT TRUNCATED AT 400 WORDS)
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|---|---|---|---|---|
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| GABA<sub>B</sub> Receptors: are they Missing in Action in Focal Epilepsy Research? | Avoli M et al. | β | 2022 | β |
| The effect of GABA-B receptors in the basolateral amygdala on passive avoidance memory impairment induced by MK-801 in rats. | Khakpoor M et al. | β | 2021 | β |
| Differential distribution and function of GABA<sub>B</sub>Rs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits. | Kulik Γ et al. | β | 2018 | β |
| Pre- and Postsynaptic Activation of GABA<sub>B</sub> Receptors Modulates Principal Cell Excitation in the Piriform Cortex. | Gerrard LB et al. | β | 2018 | β |
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| Mechanosensory Stimulation Evokes Acute Concussion-Like Behavior by Activating GIRKs Coupled to Muscarinic Receptors in a Simple Vertebrate. | Li WC et al. | β | 2017 | β |
| Hippocampal GABAergic transmission: a new target for adenosine control of excitability. | Rombo DM et al. | β | 2016 | β |
| Compartmental distribution of GABAB receptor-mediated currents along the somatodendritic axis of hippocampal principal cells. | Degro CE et al. | β | 2015 | β |
| GIRK Channel Plasticity and Implications for Drug Addiction. | Marron Fernandez de Velasco E et al. | β | 2015 | β |
| GABAB Receptors Regulate Extrasynaptic GABAA Receptors. | Connelly WM et al. | β | 2013 | β |
| Family-based genome-wide association study of frontal ΞΈ oscillations identifies potassium channel gene KCNJ6. | Kang SJ et al. | β | 2012 | β |
| Influence of a subtype of inhibitory interneuron on stimulus-specific responses in visual cortex. | Mao R et al. | β | 2012 | β |
| Somatic and dendritic GABA(B) receptors regulate neuronal excitability via different mechanisms. | Breton JD et al. | β | 2012 | β |
| Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. | LΓΌscher C et al. | β | 2010 | β |
| GABAB receptors modulate NMDA receptor calcium signals in dendritic spines. | Chalifoux JR et al. | β | 2010 | β |
| Historical perspective and emergence of the GABAB receptor. | Bowery NG | β | 2010 | β |
| Baclofen dose-dependently disrupts learning in a place avoidance task requiring cognitive coordination. | Stuchlik A et al. | β | 2009 | β |
| GABA(A) receptors in normal development and seizures: friends or foes? | Galanopoulou AS | β | 2008 | β |
| Asynchronous inputs and NMDA conductances predict excitatory responses in the cortical-cA1 pathway of the hippocampus. | Longden KD et al. | β | 2007 | β |
| Postnatal development of GABAB-receptor-mediated modulation of potassium currents in brainstem respiratory network of mouse. | Pfeiffer A et al. | β | 2007 | β |
| Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. | Kulik A et al. | β | 2006 | β |
| GABA(B) receptors and synaptic modulation. | Kornau HC | β | 2006 | β |
| Cellular and molecular mechanisms of epilepsy in the human brain. | Avoli M et al. | β | 2005 | β |
| Chronic suppression of activity in barrel field cortex downregulates sensory responses in contralateral barrel field cortex. | Li L et al. | β | 2005 | β |
| Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons. | Chen X et al. | β | 2005 | β |
| Subcellular vesicular aggregations of GABAB R1a and R1b receptors increase with age in neurons of the developing mouse brain. | Ritter B et al. | β | 2005 | β |
| Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked. | Kantrowitz JT et al. | β | 2005 | β |
| Chronic NGF treatment of rat nociceptive DRG neurons in culture facilitates desensitization and deactivation of GABAA receptor-mediated currents. | Fabbro A et al. | β | 2004 | β |
| GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex. | D'Antuono M et al. | β | 2004 | β |
| Immunocytochemical localization of GABABR1 receptor subunits in the basolateral amygdala. | McDonald AJ et al. | β | 2004 | β |
| Molecular structure and physiological functions of GABA(B) receptors. | Bettler B et al. | β | 2004 | β |
| My close encounter with GABA(B) receptors. | Nicoll RA | β | 2004 | β |
| Presynaptic inactivation of action potentials and postsynaptic inhibition of GABAA currents contribute to KA-induced disinhibition in CA1 pyramidal neurons. | Kang N et al. | β | 2004 | β |
| Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein-gated inwardly rectifying potassium currents in cultured hippocampal neurons. | Leaney JL | β | 2003 | β |
| Excitatory actions of GABA in the cortex. | Gulledge AT et al. | β | 2003 | β |
| Partial hippocampal kindling increases GABAB receptor-mediated postsynaptic currents in CA1 pyramidal cells. | Liu X et al. | β | 2003 | β |
| Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. | Kulik A et al. | β | 2003 | β |
| Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus. | Motalli R et al. | β | 2002 | β |
| GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. | MuΓ±oz A et al. | β | 2002 | β |
| GABA-B-related activity in processing of transcallosal response in cat motor cortex. | Chowdhury SA et al. | β | 2002 | β |
| Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.). | Menzikov S et al. | β | 2002 | β |
| Masking synchronous GABA-mediated potentials controls limbic seizures. | Barbarosie M et al. | β | 2002 | β |
| Neurotoxicity of lindane and picrotoxin: neurochemical and electrophysiological correlates in the rat hippocampus in vivo. | Nyitrai G et al. | β | 2002 | β |
| 5-HT1A and 5-HT2 receptors differentially regulate the excitability of 5-HT-containing neurones of the guinea pig dorsal raphe nucleus in vitro. | Craven RM et al. | β | 2001 | β |
| Comparative immunohistochemical localisation of GABA(B1a), GABA(B1b) and GABA(B2) subunits in rat brain, spinal cord and dorsal root ganglion. | Charles KJ et al. | β | 2001 | β |
| GABA(A)-dependent chloride influx modulates reversal potential of GABA(B)-mediated IPSPs in hippocampal pyramidal cells. | Lopantsev V et al. | β | 2001 | β |
| Differential expression of gamma-aminobutyric acid type B receptor-1a and -1b mRNA variants in GABA and non-GABAergic neurons of the rat brain. | Liang F et al. | β | 2000 | β |
| GABAB receptors mediate frequency-dependent depression of excitatory potentials in rat perirhinal cortex in vitro. | Ziakopoulos Z et al. | β | 2000 | β |
| GABA mediates presynaptic inhibition at glycinergic synapses in a rat auditory brainstem nucleus. | Lim R et al. | β | 2000 | β |
| GABA spillover activates postsynaptic GABA(B) receptors to control rhythmic hippocampal activity. | Scanziani M | β | 2000 | β |
| Layer-specific immunocytochemical localization of GABA(B)R1a and GABA(B)R1b receptors in the rat piriform cortex. | Princivalle A et al. | β | 2000 | β |
| Responses of rat subicular neurons to convergent stimulation of lateral entorhinal cortex and CA1 in vivo. | Gigg J et al. | β | 2000 | β |
| Differential induction of long-lasting potentiation of inhibitory postsynaptic potentials by theta patterned stimulation versus 100-Hz tetanization in hippocampal pyramidal cells in vitro. | Perez Y et al. | β | 1999 | β |
| Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. | Tietz EI et al. | β | 1999 | β |
| GABAA-Dependent chloride influx modulates GABAB-mediated IPSPs in hippocampal pyramidal cells. | Lopantsev V et al. | β | 1999 | β |
| GABA(B) receptor activation promotes seizure activity in the juvenile rat hippocampus. | Motalli R et al. | β | 1999 | β |
| GABA(B) receptor activation protects GABA(A) receptor from cyclic AMP-dependent down-regulation in rat cerebellar granule cells. | BarilΓ B et al. | β | 1999 | β |
| GABA(B) receptors inhibit mechanosensitivity of primary afferent endings. | Page AJ et al. | β | 1999 | β |
| GABAergic regulation of light-induced c-Fos immunoreactivity within the suprachiasmatic nucleus. | Gillespie CF et al. | β | 1999 | β |
| G protein-activated inwardly rectifying K+ (GIRK) currents in dendrites of rat neocortical pyramidal cells. | Takigawa T et al. | β | 1999 | β |
| Immunohistochemical localization of GABA(B) receptors in the rat central nervous system. | Margeta-Mitrovic M et al. | β | 1999 | β |
| Postnatal development of GABAB receptor-mediated modulation of voltage-activated Ca2+ currents in mouse brain-stem neurons. | Zhang W et al. | β | 1999 | β |
| Regional distribution and cellular localization of gamma-aminobutyric acid subtype 1 receptor mRNA in the rat brain. | Lu XY et al. | β | 1999 | β |
| The GABA(B) receptor antagonist CGP 55845A reduces presynaptic GABA(B) actions in neocortical neurons of the rat in vitro. | Deisz RA | β | 1999 | β |
| Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes. | Uezono Y et al. | β | 1998 | β |
| Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. | Corradetti R et al. | β | 1998 | β |
| Changes in [K+]o evoked by baclofen in guinea pig hippocampus. | Obrocea GV et al. | β | 1998 | β |
| Distinct GABAB actions via synaptic and extrasynaptic receptors in rat hippocampus in vitro. | Pham TM et al. | β | 1998 | β |
| Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA. | Soldo BL et al. | β | 1998 | β |
| GABAergic inhibitory control of the transient and sustained components of orientation selectivity in a model microcolumn in layer 4 of cat visual cortex. | Bush P et al. | β | 1998 | β |
| GABA-gated Cl- channels in the rat retina. | Feigenspan A et al. | β | 1998 | β |
| Hippocampal interneurons expressing glutamic acid decarboxylase and calcium-binding proteins decrease with aging in Fischer 344 rats. | Shetty AK et al. | β | 1998 | β |
| Neuroactive steroids induce GABA(A) receptor-mediated depolarizing postsynaptic potentials in hippocampal CA1 pyramidal cells of the rat. | Burg M et al. | β | 1998 | β |
| Opioid inhibition of hippocampal interneurons via modulation of potassium and hyperpolarization-activated cation (Ih) currents. | Svoboda KR et al. | β | 1998 | β |
| Physiological bases of the synchronized population spikes and slow wave of the magnetic field generated by a guinea-pig longitudinal CA3 slice preparation. | Wu J et al. | β | 1998 | β |
| Do GABAA and GABAB inhibitory postsynaptic responses originate from distinct interneurons in the hippocampus? | Nurse S et al. | β | 1997 | β |
| Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neurone in the cat visual cortex. | TamΓ‘s G et al. | β | 1997 | β |
| GABA(A) and GABA(B) agonists and antagonists alter the phase-shifting effects of light when microinjected into the suprachiasmatic region. | Gillespie CF et al. | β | 1997 | β |
| GABA-activated conductance in cultured rat inferior colliculus neurons. | Hosomi H et al. | β | 1997 | β |
| GABAergic regulation of cerebral microvascular tone in the rat. | Fergus A et al. | β | 1997 | β |
| GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus. | Drake CT et al. | β | 1997 | β |
| Heterogeneity in use-dependent depression of inhibitory postsynaptic potentials in the rat neostriatum in vitro. | Radnikow G et al. | β | 1997 | β |
| Properties of unitary IPSCs in hippocampal pyramidal cells originating from different types of interneurons in young rats. | Ouardouz M et al. | β | 1997 | β |
| The depolarizing GABA response. | Perkins KL et al. | β | 1997 | β |
| Baclofen, a selective GABAB receptor agonist, dose-dependently impairs spatial learning in rats. | McNamara RK et al. | β | 1996 | β |
| Differential regulation of 5-hydroxytryptamine release by GABAA and GABAB receptors in midbrain raphe nuclei and forebrain of rats. | Tao R et al. | β | 1996 | β |
| Effects of GABA agonists and antagonists on temperature-sensitive neurones in the rat hypothalamus. | Yakimova K et al. | β | 1996 | β |
| GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons. | Sodickson DL et al. | β | 1996 | β |
| GABAergic characteristics of transcallosal activity of cat motor cortical neurons. | Chowdhury SA et al. | β | 1996 | β |
| Identifiable Achatina giant neurones: their localizations in ganglia, axonal pathways and pharmacological features. | Takeuchi H et al. | β | 1996 | β |
| Immunohistochemical localization of the beta 2 and beta 3 subunits of the GABAA receptor in the basolateral amygdala of the rat and monkey. | McDonald AJ et al. | β | 1996 | β |
| Inhibitory effect of NPY on the picrotoxin-induced activity in the hippocampus: a behavioural and electrophysiological study. | SmiaΕowska M et al. | β | 1996 | β |
| Interneurons of the hippocampus. | Freund TF et al. | β | 1996 | β |
| Is the input to a GABAergic synapse the sole asymmetry in turtle's retinal directional selectivity? | Smith RD et al. | β | 1996 | β |
| Laminar origins of inhibitory synaptic inputs to pyramidal neurons of the rat neocortex. | Nicoll A et al. | β | 1996 | β |
| A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system. | Misgeld U et al. | β | 1995 | β |
| Bicuculline enhances the late GABAB receptor-mediated paired-pulse inhibition observed in rat hippocampal slices. | Stanford IM et al. | β | 1995 | β |
| GABAB receptors. | Kerr DI et al. | β | 1995 | β |
| G protein activation kinetics and spillover of gamma-aminobutyric acid may account for differences between inhibitory responses in the hippocampus and thalamus. | Destexhe A et al. | β | 1995 | β |
| Hydrogen peroxide hyperpolarizes rat CA1 pyramidal neurons by inducing an increase in potassium conductance. | Seutin V et al. | β | 1995 | β |
| Hyperpolarization by GABAB receptor agonists in mid-brain periaqueductal gray neurones in vitro. | Chieng B et al. | β | 1995 | β |
| Immunocytochemical localization of the alpha 1 and beta 2/3 subunits of the GABAA receptor in relation to specific GABAergic synapses in the dentate gyrus. | Nusser Z et al. | β | 1995 | β |
| Inhibition of the centrally induced increases in myocardial oxygen demand in rabbits by chronic treatment with baclofen, a selective GABAB agonist. | Tibiriçà E et al. | β | 1995 | β |
| Input-output dependence reveals the components of GABAergic modulation in rat hippocampal CA3 in vivo. | Margineanu DG et al. | β | 1995 | β |
| Neurogenetic basis of cognition: Facts and hypotheses. | Lassalle JM | β | 1995 | β |
| Neuromodulation and cortical function: modeling the physiological basis of behavior. | Hasselmo ME | β | 1995 | β |
| Serotoninergic modulation of excitability in area CA1 of the in vitro rat hippocampus. | Siarey RJ et al. | β | 1995 | β |
| 5-HT receptor sub-types: aspects of their regulation and function. | Elliott JM et al. | β | 1994 | β |
| Baclofen as an adjuvant analgesic. | Fromm GH | β | 1994 | β |
| Depolarization-induced suppression of GABAergic inhibition in rat hippocampal pyramidal cells: G protein involvement in a presynaptic mechanism. | Pitler TA et al. | β | 1994 | β |
| Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro. | Jarolimek W et al. | β | 1994 | β |
| Differential effects of centrally-active antihypertensives on 5-HT1A receptors in rat dorso-lateral septum, rat hippocampus and guinea-pig hippocampus. | Leishman DJ et al. | β | 1994 | β |
| Ionic basis of GABAA receptor channel function in the nervous system. | Kaila K | β | 1994 | β |
| Loss of calbindin-immunoreactivity in CA1 hippocampal stratum radiatum and stratum lacunosum-moleculare interneurons in the aged rat. | Potier B et al. | β | 1994 | β |
| Modulation of inhibitory synaptic transmission in the hippocampus. | Thompson SM | β | 1994 | β |
| Presynaptic actions of GABA and baclofen in CA1 region of the guinea-pig hippocampus in vitro. | Morishita W et al. | β | 1994 | β |
| Properties of isolated GABAB-mediated inhibitory postsynaptic currents in hippocampal pyramidal cells. | Ling DS et al. | β | 1994 | β |
| Reduced bicuculline response and GABAA agonist binding in aged rat hippocampus. | Post-Munson DJ et al. | β | 1994 | β |
| Selective suppression of intrinsic but not afferent fiber synaptic transmission by baclofen in the piriform (olfactory) cortex. | Tang AC et al. | β | 1994 | β |
| The pharmacology and function of central GABAB receptors. | Mott DD et al. | β | 1994 | β |
| Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development. | Strata F et al. | β | 1994 | β |
| Bicuculline-resistant paired-pulse inhibition in the rat hippocampal slice. | Higgins MJ et al. | β | 1993 | β |
| Calretinin is present in non-pyramidal cells of the rat hippocampus--III. Their inputs from the median raphe and medial septal nuclei. | AcsΓ‘dy L et al. | β | 1993 | β |
| CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons. | Jarolimek W et al. | β | 1993 | β |
| Characterization of synaptically elicited GABAB responses using patch-clamp recordings in rat hippocampal slices. | Otis TS et al. | β | 1993 | β |
| Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices. | Watts AE et al. | β | 1993 | β |
| Electrophysiological properties of neurons in the rat subiculum in vitro. | Taube JS | β | 1993 | β |
| Evidence for all-or-none regulation of neurotransmitter release: implications for long-term potentiation. | Perkel DJ et al. | β | 1993 | β |
| GABA-activated chloride channels in secretory nerve endings. | Zhang SJ et al. | β | 1993 | β |
| GABAA receptor-mediated mechanisms contribute to frequency-dependent depression of IPSPs in the hippocampus. | Benardo LS | β | 1993 | β |
| GABAB receptors modulate glycinergic inhibition and spike threshold in Xenopus embryo spinal neurones. | Wall MJ et al. | β | 1993 | β |
| GABA, THIP and baclofen inhibition of Purkinje cells and cerebellar nuclei neurons. | Billard JM et al. | β | 1993 | β |
| Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons. | Lambert NA et al. | β | 1993 | β |
| Hyperpolarization-activated currents in isolated superior colliculus-projecting neurons from rat visual cortex. | Solomon JS et al. | β | 1993 | β |
| Hyperpolarizing synaptic potentials evoked in CA1 pyramidal cells by glutamate stimulation of interneurons from the oriens/alveus border of rat hippocampal slices. I. Electrophysiological response properties. | Samulack DD et al. | β | 1993 | β |
| Hyperpolarizing synaptic potentials evoked in CA1 pyramidal cells by glutamate stimulation of interneurons from the oriens/alveus border of rat hippocampal slices. II. Sensitivity to GABA antagonists. | Samulack DD et al. | β | 1993 | β |
| Influence of GABA on neurons of the gustatory zone of the rat nucleus of the solitary tract. | Wang L et al. | β | 1993 | β |
| Local and diffuse synaptic actions of GABA in the hippocampus. | Isaacson JS et al. | β | 1993 | β |
| Monosynaptic GABA-mediated inhibitory postsynaptic potentials in CA1 pyramidal cells of hyperexcitable hippocampal slices from kainic acid-treated rats. | Williams S et al. | β | 1993 | β |
| Neocortical, hippocampal and septal parvalbumin- and somatostatin-containing neurons in young and aged rats: correlation with passive avoidance and water maze performance. | Miettinen R et al. | β | 1993 | β |
| Precision and variability in postsynaptic target selection of inhibitory cells in the hippocampal CA3 region. | GulyΓ‘s AI et al. | β | 1993 | β |
| Receptor-activated modulation in rat cortical slices as measured with a K-sensitive electrode. | Zoltay G et al. | β | 1993 | β |
| Spatial diversity of chloride transporters in hippocampal neurons. | Hara M et al. | β | 1993 | β |
| Subdivisions in the multiple GABAergic innervation of granule cells in the dentate gyrus of the rat hippocampus. | Halasy K et al. | β | 1993 | β |
| Subpopulations of GABA neurons containing somatostatin, neuropeptide Y, and parvalbumin in the dorsomedial cortex of the lizard Psammodromus algirus. | DΓ‘vila JC et al. | β | 1993 | β |
| Two kinetically distinct components of hyperpolarization-activated current in rat superior colliculus-projecting neurons. | Solomon JS et al. | β | 1993 | β |
| Adenosine inhibits the synaptic potentials in rat septal nucleus neurons mediated through pre- and postsynaptic A1-adenosine receptors. | Hasuo H et al. | β | 1992 | β |
| Assessment of epileptogenic potential: experimental, clinical and epidemiological approaches. | Edwards JG et al. | β | 1992 | β |
| Blockade by (-)baclofen of recurrent inhibition in the guinea pig dentate gyrus in vitro. | Misgeld U | β | 1992 | β |
| Calbindin D28k-containing nonpyramidal cells in the rat hippocampus: their immunoreactivity for GABA and projection to the medial septum. | TΓ³th K et al. | β | 1992 | β |
| Calretinin is present in non-pyramidal cells of the rat hippocampus--I. A new type of neuron specifically associated with the mossy fibre system. | GulyΓ‘s AI et al. | β | 1992 | β |
| Calretinin is present in non-pyramidal cells of the rat hippocampus--II. Co-existence with other calcium binding proteins and GABA. | Miettinen R et al. | β | 1992 | β |
| Convergence and segregation of septal and median raphe inputs onto different subsets of hippocampal inhibitory interneurons. | Miettinen R et al. | β | 1992 | β |
| Elevation of extracellular potassium facilitates the induction of hippocampal long-term potentiation. | Ballyk BA et al. | β | 1992 | β |
| Functional alterations in GABAergic inhibition during activity. | Prince DA et al. | β | 1992 | β |
| GABAA and pre- and post-synaptic GABAB receptor-mediated responses in the lateral geniculate nucleus. | Soltesz I et al. | β | 1992 | β |
| GABAA receptors control the excitability of neuronal populations. | Stelzer A | β | 1992 | β |
| GABAB receptor-mediated inhibitory postsynaptic potentials evoked by electrical stimulation and by glutamate stimulation of interneurons in stratum lacunosum-moleculare in hippocampal CA1 pyramidal cells in vitro. | Williams S et al. | β | 1992 | β |
| GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice. | Schreurs BG et al. | β | 1992 | β |
| Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro. | Washburn MS et al. | β | 1992 | β |
| In vivo assessment of the importance of GABA in convulsant and anticonvulsant drug action. | Joy RM et al. | β | 1992 | β |
| Modulation by GABAB receptors of spontaneous synchronous activities induced by 4-aminopyridine in the rat hippocampus. | Siniscalchi A et al. | β | 1992 | β |
| Monoclonal antibodies for ultrastructural visualization of L-baclofen-sensitive GABAB receptor sites. | Martinelli GP et al. | β | 1992 | β |
| Neuropeptide Y-containing interneurons in the hippocampus receive synaptic input from median raphe and GABAergic septal afferents. | Miettinen R et al. | β | 1992 | β |
| On the inhibitory actions of baclofen and gamma-aminobutyric acid in rat ventral midbrain culture. | Jarolimek W et al. | β | 1992 | β |
| Postsynaptic action of endogenous GABA released by nipecotic acid in the hippocampus. | SolΓs JM et al. | β | 1992 | β |
| Quantal analysis of suppressing action of baclofen on mossy fiber synapses in guinea pig hippocampus. | Hirata K et al. | β | 1992 | β |
| Receptor subtypes involved in callosally-induced postsynaptic potentials in rat frontal agranular cortex in vitro. | Kawaguchi Y | β | 1992 | β |
| Reduction of GABAB inhibitory postsynaptic potentials by serotonin via pre- and postsynaptic mechanisms in CA3 pyramidal cells of rat hippocampus in vitro. | Oleskevich S et al. | β | 1992 | β |
| Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters. | Takeuchi H | β | 1992 | β |
| Synaptic Activation of GABAA Receptors Causes a Depolarizing Potential Under Physiological Conditions in Rat Hippocampal Pyramidal Cells. | Avoli M | β | 1992 | β |
| Synaptic inputs to GABAA and GABAB receptors originate from discrete afferent neurons. | Sugita S et al. | β | 1992 | β |
| Synaptic potentials and effects of amino acid antagonists in the auditory cortex. | Cox CL et al. | β | 1992 | β |
| The actions of baclofen on neurones and synaptic transmission in the nucleus tractus solitarii of the rat in vitro. | Brooks PA et al. | β | 1992 | β |
| Uneven distribution of intracellular Cl- in rat hippocampal neurons. | Hara M et al. | β | 1992 | β |
| Acoustic chiasm. III: Nature, distribution, and sources of afferents to the lateral superior olive in the cat. | Glendenning KK et al. | β | 1991 | β |
| Actions of (-)-baclofen on rat dorsal horn neurons. | Kangrga I et al. | β | 1991 | β |
| A functional microcircuit for cat visual cortex. | Douglas RJ et al. | β | 1991 | β |
| A role for GABAB receptors in excitation and inhibition of thalamocortical cells. | Crunelli V et al. | β | 1991 | β |
| Baclofen-induced disinhibition in area CA1 of rat hippocampus is resistant to extracellular Ba2+. | Lambert NA et al. | β | 1991 | β |
| Changes in extracellular K+ evoked by GABA, THIP and baclofen in the guinea-pig hippocampal slice. | Barolet AW et al. | β | 1991 | β |
| Changes to synaptic ultrastructure in field CA1 of the rat hippocampus following intracerebroventricular injection of kainic acid. | Phelps S et al. | β | 1991 | β |
| Chronic lesion of corticostriatal fibers reduces GABAB but not GABAA binding in rat caudate putamen: an autoradiographic study. | Moratalla R et al. | β | 1991 | β |
| Convulsions and wet-dog shakes produced by systemic or intrahippocampal administration of ruthenium red in the rat. | GarcΓa-Ugalde G et al. | β | 1991 | β |
| Effects of hippocampal kindling on paired-pulse response in CA1 in vitro. | Zhao D et al. | β | 1991 | β |
| Expression of the GABAB receptor in Xenopus oocytes and desensitization by activation of protein kinase C. | Taniyama K et al. | β | 1991 | β |
| Functional assay for GABA receptor subtypes of a cockroach giant interneuron. | Hue B | β | 1991 | β |
| GABA receptor mechanisms in the central nervous system. | Sivilotti L et al. | β | 1991 | β |
| Gating of GABAergic inhibition in hippocampal pyramidal cells. | Alger BE | β | 1991 | β |
| Kindling-induced persistent alterations in the membrane and synaptic properties of CA1 pyramidal neurons. | Yamada N et al. | β | 1991 | β |
| Noradrenaline receptors participate in the regulation of GABAergic inhibition in area CA1 of the rat hippocampus. | Andreasen M et al. | β | 1991 | β |
| Paroxysmal inhibitory potentials mediated by GABAB receptors in partially disinhibited rat hippocampal slice cultures. | Scanziani M et al. | β | 1991 | β |
| Postnatal development of neuronal connections in cat visual cortex studied by intracellular recording in slice preparation. | Komatsu Y et al. | β | 1991 | β |
| Subpopulations of GABAergic neurons containing parvalbumin, calbindin D28k, and cholecystokinin in the rat hippocampus. | GulyΓ‘s AI et al. | β | 1991 | β |
| Synaptic localization of adrenergic disinhibition in the rat hippocampus. | Doze VA et al. | β | 1991 | β |
| The effect of omega-conotoxin GVIA on synaptic transmission within the nucleus accumbens and hippocampus of the rat in vitro. | Horne AL et al. | β | 1991 | β |
| The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid. | Yoon KW et al. | β | 1991 | β |
| A subset of local interneurons generate slow inhibitory postsynaptic potentials in hippocampal neurons. | Segal M | β | 1990 | β |
| Bicuculline- and Phaclofen-Resistant Hyperpolarizations Evoked by Glutamate Applications to Stratum Lacunosum-Moleculare in CA1 Pyramidal Cells of the Rat Hippocampus In Vitro. | Williams S et al. | β | 1990 | β |
| Bicuculline and picrotoxin block phase advances induced by GABA agonists in the circadian rhythm of locomotor activity in the golden hamster by a phaclofen-insensitive mechanism. | Smith RD et al. | β | 1990 | β |
| Block of GABAb-activated K+ conductance by kainate and quisqualate in rat CA3 hippocampal pyramidal neurones. | Rovira C et al. | β | 1990 | β |
| Characteristics of the prolonged inhibition produced by a range of pyrethroids in the rat hippocampus. | Joy RM et al. | β | 1990 | β |
| Differential effect of zinc on the vertebrate GABAA-receptor complex. | Smart TG et al. | β | 1990 | β |
| Differential effects of baclofen and gamma-aminobutyric acid (GABA) on rat piriform cortex pyramidal neurons in vitro. | Doi N et al. | β | 1990 | β |
| Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices. | Liou SY et al. | β | 1990 | β |
| Effects of ketamine on GABA-evoked excitability of peripheral nerve. | Liske S et al. | β | 1990 | β |
| Endogenous GABA mediates presynaptic inhibition of spontaneous and evoked excitatory synaptic potentials in the rat neostriatum. | Calabresi P et al. | β | 1990 | β |
| Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina. | Friedman DL et al. | β | 1990 | β |
| GABA(B)-related activity involved in synaptic processing of somatosensory information in S1 cortex of the anaesthetized cat. | Kaneko T et al. | β | 1990 | β |
| GABA-induced potassium channels in cultured neurons. | Premkumar LS et al. | β | 1990 | β |
| gamma-Aminobutyric acid responses in rat locus coeruleus neurones in vitro: a current-clamp and voltage-clamp study. | OsmanoviΔ SS et al. | β | 1990 | β |
| Ion conductances affected by 5-HT receptor subtypes in mammalian neurons. | Bobker DH et al. | β | 1990 | β |
| Lithium enhances neuronal muscarinic excitation by presynaptic facilitation. | Evans MS et al. | β | 1990 | β |
| Membrane properties of interneurons in stratum oriens-alveus of the CA1 region of rat hippocampus in vitro. | Lacaille JC et al. | β | 1990 | β |
| Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus. | Davies CH et al. | β | 1990 | β |
| Phaclofen inhibition of the slow inhibitory postsynaptic potential in hippocampal slice cultures: a possible role for the GABAB-mediated inhibitory postsynaptic potential. | Malouf AT et al. | β | 1990 | β |
| Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones. | Kim KH et al. | β | 1990 | β |
| Pharmacology and physiology of GABAB receptors. | Ogata N | β | 1990 | β |
| Potassium currents activated in hippocampal neurons by serotonin are mediated by a change in intracellular calcium concentrations. | Segal M | β | 1990 | β |
| Regulation of glutamate and aspartate release from the Schaffer collaterals and other projections of CA3 hippocampal pyramidal cells. | Nadler JV et al. | β | 1990 | β |
| Responses of cells of the rat fascia dentata to prolonged stimulation of the perforant path: sensitivity of hilar cells and changes in granule cell excitability. | Scharfman HE et al. | β | 1990 | β |
| Serotonergic control of the hippocampus via local inhibitory interneurons. | Freund TF et al. | β | 1990 | β |
| Single unit response of neurons within the hamster suprachiasmatic nucleus to GABA and low chloride perfusate during the day and night. | Liou SY et al. | β | 1990 | β |
| Some characteristics of baclofen-evoked responses of primary afferents in frog spinal cord. | Padjen AL et al. | β | 1990 | β |
| Spontaneous and evoked activities of anterior thalamic neurons during waking and sleep states. | ParΓ© D et al. | β | 1990 | β |
| The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice. | Rekling JC et al. | β | 1990 | β |
| The effects of baclofen and two GABAB-receptor antagonists on long-term potentiation. | Olpe HR et al. | β | 1990 | β |
| Uncultured lobster muscle, cultured neurons and brain slices: the neurophysiology of zinc. | Smart TG | β | 1990 | β |
| Variation in strength of inhibitory synapses in the CA3 region of guinea-pig hippocampus in vitro. | Miles R | β | 1990 | β |
| Actions of the GABAB agonist, (-)-baclofen, on neurones in deep dorsal horn of the rat spinal cord in vitro. | Allerton CA et al. | β | 1989 | β |
| An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells. | Peters JA et al. | β | 1989 | β |
| A new alcohol antagonist: phaclofen. | Allan AM et al. | β | 1989 | β |
| A pertussis toxin-sensitive G protein in hippocampal long-term potentiation. | Goh JW et al. | β | 1989 | β |
| Blockade of the late IPSP in rat CA1 hippocampal neurons by 2-hydroxy-saclofen. | Lambert NA et al. | β | 1989 | β |
| Carbachol reduces IK,baclofen, but not IK,GABA in guinea pig hippocampal slices. | MΓΌller W et al. | β | 1989 | β |
| Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine. | Strobel GH et al. | β | 1989 | β |
| Effect of guanosine 5'-O-(3-thiotriphosphate) and calcium on gamma-aminobutyric acidB binding as a function of postnatal development. | al-Dahan MI et al. | β | 1989 | β |
| Electrophysiological properties of rat CA1 pyramidal neurones in vitro modified by changes in extracellular bicarbonate. | Church J et al. | β | 1989 | β |
| Failure of the antiepileptic drug valproic acid to modify synaptic and non-synaptic responses of CA1 hippocampal pyramidal cells maintained 'in vitro'. | Perreault P et al. | β | 1989 | β |
| Frequency-dependent depression of inhibition in guinea-pig neocortex in vitro by GABAB receptor feed-back on GABA release. | Deisz RA et al. | β | 1989 | β |
| GABAB receptor mediated effects on central respiratory system and their antagonism by phaclofen. | Schmid K et al. | β | 1989 | β |
| gamma-Aminobutyric acid-induced ion movements in the guinea pig hippocampal slice. | MΓΌller W et al. | β | 1989 | β |
| Inhibitory processes in normal and epileptic-like rat hippocampal slices: the role of GABAB receptors. | Karlsson G et al. | β | 1989 | β |
| Involvement of a pertussis toxin-sensitive G-protein in the pharmacological properties of septo-hippocampal neurones. | Rascol O et al. | β | 1989 | β |
| Late inhibitory postsynaptic potentials in rat prefrontal cortex may be mediated by GABAB receptors. | Karlsson G et al. | β | 1989 | β |
| Mechanisms of general anesthesia: brain regional responses to baclofen. | Lewis JL et al. | β | 1989 | β |
| Reduction by baclofen of monosynaptic EPSPs in lumbosacral motoneurones of the anaesthetized cat. | Edwards FR et al. | β | 1989 | β |
| Selective depression of GABA-mediated IPSPs by somatostatin in area CA1 of rabbit hippocampal slices. | Scharfman HE et al. | β | 1989 | β |
| The effects of baclofen and pertussis toxin on epileptiform activity induced in the hippocampal slice by magnesium depletion. | Lewis DV et al. | β | 1989 | β |
| The EPSP-spike (E-S) component of long-term potentiation in the rat hippocampal slice is modulated by GABAergic but not cholinergic mechanisms. | Chavez-Noriega LE et al. | β | 1989 | β |
| Twelfth Gaddum memorial lecture. Drug receptors and the inhibition of nerve cells. | North RA | β | 1989 | β |
| Activation of type B gamma-aminobutyric acid receptors in the intact mammalian spinal cord mimics the effects of reduced presynaptic Ca2+ influx. | Lev-Tov A et al. | β | 1988 | β |
| Agonists at mu-opioid, M2-muscarinic and GABAB-receptors increase the same potassium conductance in rat lateral parabrachial neurones. | Christie MJ et al. | β | 1988 | β |
| A physiological role for GABAB receptors in the central nervous system. | Dutar P et al. | β | 1988 | β |
| A potassium conductance contributes to the action of somatostatin-14 to suppress ACTH secretion. | Pennefather PS et al. | β | 1988 | β |
| (-)-Baclofen activates presynaptic GABAB receptors on GABAergic inhibitory neurons from embryonic rat hippocampus. | Harrison NL et al. | β | 1988 | β |
| Baclofen and gamma-aminobutyric acid differentially suppress the cutaneous responsiveness of primary somatosensory cortical neurones. | Kaneko T et al. | β | 1988 | β |
| Baclofen increases the potassium conductance of rat locus coeruleus neurons recorded in brain slices. | OsmanoviΔ SS et al. | β | 1988 | β |
| Cl- - and K+-dependent inhibitory postsynaptic potentials evoked by interneurones of the rat lateral geniculate nucleus. | Crunelli V et al. | β | 1988 | β |
| Comparison of antagonism by phaclofen of baclofen induced hyperpolarizations and synaptically mediated late hyperpolarizing potentials recorded intracellularly from rat dorsolateral septal neurons. | Hasuo H et al. | β | 1988 | β |
| Complex effects of baclofen on synaptic transmission of the frog optic tectum in vitro. | Sivilotti L et al. | β | 1988 | β |
| Decrease of recurrent and feed-forward inhibitions under high pressure of helium in rat hippocampal slices. | Zinebi F et al. | β | 1988 | β |
| Development of GABA responsiveness in embryonic turtle cortical neurons. | Shen JM et al. | β | 1988 | β |
| Dorsal horn neuropharmacology: baclofen and morphine. | ZieglgΓ€nsberger W | β | 1988 | β |
| Effects of GABA and baclofen on pyramidal cells in the developing rabbit hippocampus: an 'in vitro' study. | Janigro D et al. | β | 1988 | β |
| Effects of GABA on CA3 pyramidal cell dendrites in rabbit hippocampal slices. | Janigro D et al. | β | 1988 | β |
| Epileptiform activity induced by 4-aminopyridine in immature hippocampus. | Chesnut TJ et al. | β | 1988 | β |
| Epileptiform events induced by GABA-antagonists in entorhinal cortical cells in vitro are partly mediated by N-methyl-D-aspartate receptors. | Jones RS | β | 1988 | β |
| Evidence for G protein mediation of serotonin- and GABAB-induced hyperpolarization of rat dorsal raphe neurons. | Innis RB et al. | β | 1988 | β |
| GABAergic inhibition and the induction of spontaneous epileptiform activity by low chloride and high potassium in the hippocampal slice. | Chamberlin NL et al. | β | 1988 | β |
| Inhibition of neuronal membrane GABAB receptor binding by GABA structural analogues. | Tunnicliff G et al. | β | 1988 | β |
| Intracellular responses of rat hippocampal granule cells in vitro to discrete applications of norepinephrine. | Lacaille JC et al. | β | 1988 | β |
| Long-lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid. | Ben-Ari Y et al. | β | 1988 | β |
| Muscarinic inhibitory effect in the guinea pig dentate gyrus in vitro. | Brunner H et al. | β | 1988 | β |
| Neural plasticity without postsynaptic action potentials: less-active inputs become dominant when kitten visual cortical cells are pharmacologically inhibited. | Reiter HO et al. | β | 1988 | β |
| Norepinephrine decreases synaptic inhibition in the rat hippocampus. | Madison DV et al. | β | 1988 | β |
| On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones. | Lacey MG et al. | β | 1988 | β |
| Pertussis toxin pretreatment discriminates between pre- and postsynaptic actions of baclofen in rat dorsal raphe nucleus in vitro. | Colmers WF et al. | β | 1988 | β |
| Phaclofen antagonizes baclofen-induced suppression of visually evoked responses in the cat's striate cortex. | Baumfalk U et al. | β | 1988 | β |
| Potential interactions between GABAb and cholinergic systems: baclofen augments scopolamine-induced performance deficits in the eight-arm radial maze. | Sidel ES et al. | β | 1988 | β |
| Pre- and postsynaptic GABAB receptors in the hippocampus have different pharmacological properties. | Dutar P et al. | β | 1988 | β |
| Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen. | Burke SP et al. | β | 1988 | β |
| Repetitive excitation of bursts of action potentials in the rat hippocampus following single shock stimulation. | Giacchino JL et al. | β | 1988 | β |
| The coupling of neurotransmitter receptors to ion channels in the brain. | Nicoll RA | β | 1988 | β |
| The GABAB antagonist phaclofen inhibits the late K+-dependent IPSP in cat and rat thalamic and hippocampal neurones. | Soltesz I et al. | β | 1988 | β |
| Two inhibitory postsynaptic potentials, and GABAA and GABAB receptor-mediated responses in neocortex of rat and cat. | Connors BW et al. | β | 1988 | β |
| Ultrastructure of stratum lacunosum-moleculare interneurons of hippocampal CA1 region. | Kunkel DD et al. | β | 1988 | β |
| A synaptically evoked late hyperpolarization in the rat dorsolateral geniculate neurons in vitro. | Hirsch JC et al. | β | 1987 | β |
| Baclofen disrupts passive avoidance retention in rats. | Swartzwelder HS et al. | β | 1987 | β |
| Baclofen inhibits the spontaneous and visually evoked responses of neurones in the striate cortex of the cat. | Baumfalk U et al. | β | 1987 | β |
| Baclofen reduces post-synaptic potentials of rat cortical neurones by an action other than its hyperpolarizing action. | Howe JR et al. | β | 1987 | β |
| Baclofen responsive posttraumatic epilepsy. | Sandyk R et al. | β | 1987 | β |
| Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus. | Worley PF et al. | β | 1987 | β |
| Contrasting properties of K+ conductances induced by baclofen and gamma-aminobutyric acid in slices of the guinea pig hippocampus. | Ogata N et al. | β | 1987 | β |
| Contribution of chloride shifts to the fade of gamma-aminobutyric acid-gated currents in frog dorsal root ganglion cells. | Akaike N et al. | β | 1987 | β |
| Distribution and ultrastructure of neurons in opossum piriform cortex displaying immunoreactivity to GABA and GAD and high-affinity tritiated GABA uptake. | Haberly LB et al. | β | 1987 | β |
| Effects of hypoxia on rat hippocampal neurones in vitro. | Fujiwara N et al. | β | 1987 | β |
| GABAB-receptor mediated inhibition of potassium-evoked release of endogenous 5-hydroxytryptamine from mouse frontal cortex. | Gray JA et al. | β | 1987 | β |
| GABAergic mechanisms of analgesia: an update. | Sawynok J | β | 1987 | β |
| gamma-Aminobutyric acid (GABA) causes consistent depolarization of neurons in the guinea pig supraoptic nucleus due to an absence of GABAB recognition sites. | Ogata N | β | 1987 | β |
| Intracellular effectors and modulators of GABA-A and GABA-B receptors: a commentary. | Feltz A et al. | β | 1987 | β |
| Low concentrations of GABA reduce accommodation in primary afferent neurons by an action at GABAB receptors. | Schlichter R et al. | β | 1987 | β |
| Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. | North RA et al. | β | 1987 | β |
| Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons. | Innis RB et al. | β | 1987 | β |
| Pertussis toxin blocks a late inhibitory postsynaptic potential in hippocampal CA3 neurons. | Thalmann RH | β | 1987 | β |
| Phaclofen: a peripheral and central baclofen antagonist. | Kerr DI et al. | β | 1987 | β |
| Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones. | Lancaster B et al. | β | 1987 | β |
| Quantitative autoradiography of hippocampal GABAB and GABAA receptor changes in Alzheimer's disease. | Chu DC et al. | β | 1987 | β |
| Responses to GABA recorded from identified rat visual cortical neurons. | Scharfman HE et al. | β | 1987 | β |
| The location of GABAB receptor binding sites in mammalian spinal cord. | Price GW et al. | β | 1987 | β |
| Voltage-clamp analysis of somatic gamma-aminobutyric acid responses in adult rat hippocampal CA1 neurones in vitro. | Ashwood TJ et al. | β | 1987 | β |
| Activation of thermogenesis of brown fat in rats by baclofen. | Addae JI et al. | β | 1986 | β |
| Adenosine inhibits epileptiform activity arising in hippocampal area CA3. | Ault B et al. | β | 1986 | β |
| A G protein couples serotonin and GABAB receptors to the same channels in hippocampus. | Andrade R et al. | β | 1986 | β |
| A pharmacological study of group I muscle afferent terminals and synaptic excitation in the intermediate nucleus and Clarke's column of the cat spinal cord. | Curtis DR et al. | β | 1986 | β |
| Baclofen suppresses bursting activity induced in hippocampal slices by differing convulsant treatments. | Ault B et al. | β | 1986 | β |
| Effects of baclofen and gamma-aminobutyric acid on different types of medullary respiratory neurons. | Lalley PM | β | 1986 | β |
| Effects of GABA and bicuculline on N-methyl-D-aspartate- and quisqualate-induced reductions in extracellular free calcium in area CA1 of the hippocampal slice. | Hamon B et al. | β | 1986 | β |
| Effects of gamma-aminobutyric acid and (-)-baclofen on calcium and potassium currents in cat dorsal root ganglion neurones in vitro. | Robertson B et al. | β | 1986 | β |
| Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina. | Kaneko A et al. | β | 1986 | β |
| GABAA and GABAB receptors on porcine pars intermedia cells in primary culture: functional role in modulating peptide release. | Demeneix BA et al. | β | 1986 | β |
| Inhibition of calcium currents in cultured rat dorsal root ganglion neurones by (-)-baclofen. | Dolphin AC et al. | β | 1986 | β |
| Loss of inhibition in the CA1 region of the kainic acid lesioned hippocampus is not associated with changes in postsynaptic responses to GABA. | Ashwood TJ et al. | β | 1986 | β |
| Neurons accumulating [3H]gamma-aminobutyric acid (GABA) in supragranular layers of cat primary auditory cortex (AI) | Winer JA | β | 1986 | β |
| Potent depressant action of baclofen on hippocampal epileptiform activity in vitro: possible use in the treatment of epilepsy. | Ogata N et al. | β | 1986 | β |
| Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation. | Kemp JA et al. | β | 1986 | β |
| The action of valproate on spontaneous epileptiform activity in the absence of synaptic transmission and on evoked changes in [Ca2+]o and [K+]o in the hippocampal slice. | Franceschetti S et al. | β | 1986 | β |
| The control of retinogeniculate transmission in the mammalian lateral geniculate nucleus. | Sherman SM et al. | β | 1986 | β |
| Adenosine-activated potassium conductance in cultured striatal neurons. | Trussell LO et al. | β | 1985 | β |
| Further studies on the action of baclofen on neurons of the dorsolateral septal nucleus of the rat, in vitro. | Stevens DR et al. | β | 1985 | β |
| Possible involvement of K+-conductance in the action of gamma-aminobutyric acid in the guinea-pig hippocampus. | Inoue M et al. | β | 1985 | β |