The IKK NF-kappa B system: a treasure trove for drug development.
paper
Cited
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- Authors
- Karin, Michael; Yamamoto, Yumi; Wang, Q May
- Year
- 2004
- Journal
- Nature reviews. Drug discovery
- PMID
- 14708018
- DOI
- 10.1038/nrd1279
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| Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy. | Wu KJ et al. | — | 2019 | → |
| Tangeretin inhibits streptozotocin-induced cell apoptosis via regulating NF-κB pathway in INS-1 cells. | Liu Y et al. | — | 2019 | → |
| Targeting NF-κB-mediated inflammatory pathways in cisplatin-resistant NSCLC. | Ryan SL et al. | — | 2019 | → |
| The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells. | Lung HL et al. | — | 2019 | → |
| What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion? | Albensi BC | — | 2019 | → |
| Xanthatin inhibits STAT3 and NF-κB signalling by covalently binding to JAK and IKK kinases. | Liu M et al. | — | 2019 | → |
| 3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent. | Kerns JK et al. | — | 2018 | → |
| Aberrant Activation of NF-κB Signalling in Aggressive Lymphoid Malignancies. | Kennedy R et al. | — | 2018 | → |
| Anti-inflammatory effect of ATB-352, a H2S -releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats. | Gugliandolo E et al. | — | 2018 | → |
| Antinociceptive and anti-inflammatory activities of a standardizedextract of bis-iridoids from Pterocephalus hookeri. | Chen Y et al. | — | 2018 | → |
| Aqueous extract of Sapindus mukorossi induced cell death of A549 cells and exhibited antitumor property in vivo. | Liu M et al. | — | 2018 | → |
| Dauricine combined with clindamycin inhibits severe pneumonia co-infected by influenza virus H5N1 and Streptococcus pneumoniae in vitro and in vivo through NF-κB signaling pathway. | Li H et al. | — | 2018 | → |
| Downregulation of β1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation. | Li SF et al. | — | 2018 | → |
| Effect of two recombinant Trichinella spiralis serine protease inhibitors on TNBS-induced experimental colitis of mice. | Xu J et al. | — | 2018 | → |
| Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression. | Puar YR et al. | — | 2018 | → |
| Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy. | Moustafa PE et al. | — | 2018 | → |
| IFN-γ Induces Gastric Cancer Cell Proliferation and Metastasis Through Upregulation of Integrin β3-Mediated NF-κB Signaling. | Xu YH et al. | — | 2018 | → |
| Inhibition of focal adhesion kinase overcomes resistance of mantle cell lymphoma to ibrutinib in the bone marrow microenvironment. | Rudelius M et al. | — | 2018 | → |
| Intracelluar delivery of A20 protein inhibits TNFα-induced NF-κB activation. | Lee HR et al. | — | 2018 | → |
| JSH-23 prevents depressive-like behaviors in mice subjected to chronic mild stress: Effects on inflammation and antioxidant defense in the hippocampus. | Wang Q et al. | — | 2018 | → |
| Linear Energy Transfer Modulates Radiation-Induced NF-kappa B Activation and Expression of its Downstream Target Genes. | Chishti AA et al. | — | 2018 | → |
| Lung Cancer Chemopreventive Activity of Patulin Isolated from Penicillium vulpinum. | Monteillier A et al. | — | 2018 | → |
| Maslinic acid protects against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. | Wang YY et al. | — | 2018 | → |
| Mechanisms of NF-κB p65 and strategies for therapeutic manipulation. | Giridharan S et al. | — | 2018 | → |
| mTORC1 accelerates retinal development via the immunoproteasome. | Choi JH et al. | — | 2018 | → |
| Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas. | Jour G et al. | — | 2018 | → |
| Oxidative stress in autoimmune rheumatic diseases. | Smallwood MJ et al. | — | 2018 | → |
| Phosphorylation-induced changes in the energetic frustration in human Tank binding kinase 1. | Husain S et al. | — | 2018 | → |
| Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin. | Cavaleri F | — | 2018 | → |
| Repurposing Thioridazine (TDZ) as an anti-inflammatory agent. | Baig MS et al. | — | 2018 | → |
| Signaling by cell surface death receptors: Alterations in head and neck cancer. | Leonard BC et al. | — | 2018 | → |
| Study on the influence of caffeic acid against sodium valproate-induced nephrotoxicity in rats. | Gad AM | — | 2018 | → |
| Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation. | Hiramatsu T et al. | — | 2018 | → |
| The Immunomodulatory and Anti-Inflammatory Role of Polyphenols. | Yahfoufi N et al. | — | 2018 | → |
| TRAF6 mediates high glucose-induced endothelial dysfunction. | Liu R et al. | — | 2018 | → |
| Wide-range screening of anti-inflammatory compounds in tomato using LC-MS and elucidating the mechanism of their functions. | Mohri S et al. | — | 2018 | → |
| Wood-cultivated ginseng exerts anti-inflammatory effect in LPS-stimulated RAW264.7 cells. | Park SB et al. | — | 2018 | → |
| Adverse Health Effects of Betel Quid and the Risk of Oral and Pharyngeal Cancers. | Chen PH et al. | — | 2017 | → |
| Allium hookeri root extract exerts anti-inflammatory effects by nuclear factor-κB down-regulation in lipopolysaccharide-induced RAW264.7 cells. | Jang JY et al. | — | 2017 | → |
| Anti-cancer effects of dopamine in human glioma: involvement of mitochondrial apoptotic and anti-inflammatory pathways. | Lan YL et al. | — | 2017 | → |
| Anti-Inflammatory Potential of 1-Nitro-2-Phenylethylene. | Sugimoto MA et al. | — | 2017 | → |
| Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages. | Park JY et al. | — | 2017 | → |
| A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer <i>in vivo</i> and <i>in vitro</i>. | Zheng J et al. | — | 2017 | → |
| Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. | Noh H et al. | — | 2017 | → |
| Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation. | Kiasalari Z et al. | — | 2017 | → |
| Discovery of Potent Small-Molecule Inhibitors of Ubiquitin-Conjugating Enzyme UbcH5c from α-Santonin Derivatives. | Chen H et al. | — | 2017 | → |
| Early interleukin-6 enhances hepatic ketogenesis in APP<sub>SWE</sub>/PSEN1dE9 mice via 3-hydroxy-3-methylglutary-CoA synthase 2 signaling activation by p38/nuclear factor κB p65. | Shi L et al. | — | 2017 | → |
| Endocan silencing induces programmed cell death in hepatocarcinoma. | Yang J et al. | — | 2017 | → |
| Fas/S1P<sub>1</sub> crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. | Hutami IR et al. | — | 2017 | → |
| IκB kinase inhibition as a potential treatment of osteoarthritis - results of a clinical proof-of-concept study. | Grothe K et al. | — | 2017 | → |
| miR-429 is involved in regulation of NF-κBactivity by targeting IKKβ and suppresses oncogenic activity in cervical cancer cells. | Fan JY et al. | — | 2017 | → |
| Multi-Targeting Andrographolide, a Novel NF-κB Inhibitor, as a Potential Therapeutic Agent for Stroke. | Yang CH et al. | — | 2017 | → |
| Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways. | Olmedo DA et al. | — | 2017 | → |
| Netrin-1 is a novel regulator of vascular endothelial function in diabetes. | Toque HA et al. | — | 2017 | → |
| New Insights toward Colorectal Cancer Chemotherapy Using Natural Bioactive Compounds. | Redondo-Blanco S et al. | — | 2017 | → |
| NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases. | Lin TH et al. | — | 2017 | → |
| Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes. | Yuan X et al. | — | 2017 | → |
| Nuclear factor-κB expression in the endometrium of normal and overweight women with polycystic ovary syndrome. | Koc O et al. | — | 2017 | → |
| Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity. | Hu L et al. | — | 2017 | → |
| Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells. | Tartey S et al. | — | 2017 | → |
| Regulation of expression and trafficking of perforin-2 by LPS and TNF-α. | Xiong P et al. | — | 2017 | → |
| Role of NF-κB activation and Th1/Th2 imbalance in pulmonary toxicity induced by nano NiO. | Chang X et al. | — | 2017 | → |
| Role of the inflammasome in chronic obstructive pulmonary disease (COPD). | Colarusso C et al. | — | 2017 | → |
| SETD6 regulates NF-κB signaling in urothelial cell survival: Implications for bladder cancer. | Mukherjee N et al. | — | 2017 | → |
| Solasonine inhibits glioma growth through anti-inflammatory pathways. | Wang X et al. | — | 2017 | → |
| Study of the inhibitory effects on TNF-α-induced NF-κB activation of IMD0354 analogs. | Li YR et al. | — | 2017 | → |
| Suppression of LPS-induced NF-κB activity in macrophages by the synthetic aurone, (Z)-2-((5-(hydroxymethyl) furan-2-yl) methylene) benzofuran-3(2H)-one. | Park HS et al. | — | 2017 | → |
| Synthesis of coumaperine derivatives: Their NF-κB inhibitory effect, inhibition of cell migration and their cytotoxic activity. | Nandakumar N et al. | — | 2017 | → |
| Targeting Chromatin Remodeling in Inflammation and Fibrosis. | Yang J et al. | — | 2017 | → |
| Targeting IKK and NF-κB for Therapy. | Durand JK et al. | — | 2017 | → |
| Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile. | Widen JC et al. | — | 2017 | → |
| Targeting Stemness: Implications for Precision Medicine in Breast Cancer. | Liang ZM et al. | — | 2017 | → |
| Targeting the Canonical Nuclear Factor-κB Pathway with a High-Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome. | Fowler KA et al. | — | 2017 | → |
| The effects of rotenone-induced toxicity via the NF-κB-iNOS pathway in rat liver. | Jiang X et al. | — | 2017 | → |
| Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity. | Begalli F et al. | — | 2017 | → |
| Withanolides against TLR4-Activated Innate Inflammatory Signalling Pathways: A Comparative Computational and Experimental Study. | Purushotham PM et al. | — | 2017 | → |
| Anti-inflammatory and anti-osteoclastogenic effects of zinc finger protein A20 overexpression in human periodontal ligament cells. | Hong JY et al. | — | 2016 | → |
| Anti-oxidative and anti-inflammatory effects of cinnamaldehyde on protecting high glucose-induced damage in cultured dorsal root ganglion neurons of rats. | Yang D et al. | — | 2016 | → |
| Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells. | Zeng YP et al. | — | 2016 | → |
| Association of REL polymorphisms and outcome of patients with septic shock. | Toubiana J et al. | — | 2016 | → |
| Bioactivities and Health Benefits of Wild Fruits. | Li Y et al. | — | 2016 | → |
| Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging. | Shcherbakova DM et al. | — | 2016 | → |
| Caffeine prevents LPS-induced inflammatory responses in RAW264.7 cells and zebrafish. | Hwang JH et al. | — | 2016 | → |
| Cancer cachexia-when proteasomal inhibition is not enough. | Fielitz J | — | 2016 | → |
| Cancer therapy targeting the fibrinolytic system. | Heissig B et al. | — | 2016 | → |
| Chimeric Vaccine Stimulation of Human Dendritic Cell Indoleamine 2, 3-Dioxygenase Occurs via the Non-Canonical NF-κB Pathway. | Kim NS et al. | — | 2016 | → |
| Coffee inhibits nuclear factor-kappa B in prostate cancer cells and xenografts. | Kolberg M et al. | — | 2016 | → |
| Colchicine to decrease NLRP3-activated inflammation and improve obesity-related metabolic dysregulation. | Demidowich AP et al. | — | 2016 | → |
| Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines. | Saber MM et al. | — | 2016 | → |
| Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells. | Jin R et al. | — | 2016 | → |
| Dihydromyricetin suppresses inflammatory responses in vitro and in vivo through inhibition of IKKβ activity in macrophages. | Wang R et al. | — | 2016 | → |
| Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project. | Waltenberger B et al. | — | 2016 | → |
| Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis. | Ruan ZB et al. | — | 2016 | → |
| Effect of Selenium Against Lead-Induced Damage on the Gene Expression of Heat Shock Proteins and Inflammatory Cytokines in Peripheral Blood Lymphocytes of Chickens. | Sun GX et al. | — | 2016 | → |
| Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI. | Ali AA et al. | — | 2016 | → |
| Grape-seed proanthocyanidins inhibit the lipopolysaccharide-induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF-κb signal pathways. | Chu H et al. | — | 2016 | → |
| Identification and characterization of potent, selective and metabolically stable IKKβ inhibitor. | Kim D et al. | — | 2016 | → |
| Identification of a Novel Function of Adipocyte Plasma Membrane-Associated Protein (APMAP) in Gestational Diabetes Mellitus by Proteomic Analysis of Omental Adipose Tissue. | Ma Y et al. | — | 2016 | → |
| Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua). | Parhira S et al. | — | 2016 | → |
| Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer. | Kim M et al. | — | 2016 | → |
| Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked? | Rehman K et al. | — | 2016 | → |
| mTOR, cardiomyocytes and inflammation in cardiac hypertrophy. | Xu L et al. | — | 2016 | → |
| Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors. | Swarnkar G et al. | — | 2016 | → |
| New IKK inhibitors: Synthesis of new imidazo[1,2-a]quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors. | Moarbess G et al. | — | 2016 | → |
| Novel Anthra[1,2-c][1,2,5]Thiadiazole-6,11-Diones as Promising Anticancer Lead Compounds: Biological Evaluation, Characterization & Molecular Targets Determination. | Ali AA et al. | — | 2016 | → |
| Optimization and biological evaluation of aminopyrimidine-based IκB kinase β inhibitors with potent anti-inflammatory effects. | Shin Y et al. | — | 2016 | → |
| Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB. | Yu G et al. | — | 2016 | → |
| Potential dual role of nuclear factor-kappa B in experimental subarachnoid hemorrhage-induced early brain injury in rabbits. | You W et al. | — | 2016 | → |
| Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy. | Jiang T et al. | — | 2016 | → |
| Protective effects of Yinhuapinggan granule on mice with influenza viral pneumonia. | Peng XQ et al. | — | 2016 | → |
| Pyrroloquinoline Quinone Decelerates Rheumatoid Arthritis Progression by Inhibiting Inflammatory Responses and Joint Destruction via Modulating NF-κB and MAPK Pathways. | Liu Z et al. | — | 2016 | → |
| Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats. | Bhaskar S et al. | — | 2016 | → |
| Resolution of Inflammation: What Controls Its Onset? | Sugimoto MA et al. | — | 2016 | → |
| The Antagonistic Effect of Selenium on Lead-Induced Inflammatory Factors and Heat Shock Protein mRNA Level in Chicken Cartilage Tissue. | Zheng S et al. | — | 2016 | → |
| The effect of an IκB-kinase-β(IKKβ) inhibitor on tobacco smoke-induced pulmonary inflammation. | Choi SI et al. | — | 2016 | → |
| The Pharmacological Effects and Mechanism of Tripterygium wilfordii Hook F in Central Nervous System Autoimmunity. | Wang Q et al. | — | 2016 | → |
| The Role of Cyclo(His-Pro) in Neurodegeneration. | Grottelli S et al. | — | 2016 | → |
| The role of deubiquitinases in breast cancer. | Xiao Z et al. | — | 2016 | → |
| Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. | Li Y et al. | — | 2016 | → |
| β-Ionone and its analogs as promising anticancer agents. | Ansari M et al. | — | 2016 | → |
| 3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages. | Matsebatlela TM et al. | — | 2015 | → |
| Antioxidation and anti-inflammatory activity of Tang Bi Kang in rats with diabetic peripheral neuropathy. | Yang XW et al. | — | 2015 | → |
| A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ. | Maroni D et al. | — | 2015 | → |
| Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status. | Klammer H et al. | — | 2015 | → |
| Co-expression of β-arrestin1 and NF-кB is associated with cancer progression and poor prognosis in lung adenocarcinoma. | Yu J et al. | — | 2015 | → |
| Computational design and discovery of nanomolar inhibitors of IκB kinase β. | Park H et al. | — | 2015 | → |
| Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities. | Cardoso MV et al. | — | 2015 | → |
| Discovery of small molecule CD40-TRAF6 inhibitors. | Zarzycka B et al. | — | 2015 | → |
| EGFR and NF-κB: partners in cancer. | Shostak K et al. | — | 2015 | → |
| Exploiting replicative stress to treat cancer. | Dobbelstein M et al. | — | 2015 | → |
| FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression. | Xu HD et al. | — | 2015 | → |
| From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition? | Szarc vel Szic K et al. | — | 2015 | → |
| HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals. | Bandarra D et al. | — | 2015 | → |
| High expression of valosin-containing protein predicts poor prognosis in patients with breast carcinoma. | Cui Y et al. | — | 2015 | → |
| Hysteroscopic polypectomy decreases NF-κB1 expression in the mid-secretory endometrium of women with endometrial polyp. | Bozkurt M et al. | — | 2015 | → |
| Identification of novel focal adhesion kinase substrates: role for FAK in NFκB signaling. | Dwyer SF et al. | — | 2015 | → |
| IKK2 inhibition using TPCA-1-loaded PLGA microparticles attenuates laser-induced choroidal neovascularization and macrophage recruitment. | Gaddipati S et al. | — | 2015 | → |
| Lazaroid U-74389G inhibits the osteoblastic differentiation of IL-1β-indcued aortic valve interstitial cells through glucocorticoid receptor and inhibition of NF-κB pathway. | Sun F et al. | — | 2015 | → |
| Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products. | Ma J et al. | — | 2015 | → |
| MAP17 (PDZKIP1) Expression Determines Sensitivity to the Proteasomal Inhibitor Bortezomib by Preventing Cytoprotective Autophagy and NFκB Activation in Breast Cancer. | Muñoz-Galván S et al. | — | 2015 | → |
| Marine Diterpenoids as Potential Anti-Inflammatory Agents. | González Y et al. | — | 2015 | → |
| MCPIP1 Regulates Fibroblast Migration in 3-D Collagen Matrices Downstream of MAP Kinases and NF-κB. | Chao J et al. | — | 2015 | → |
| Mechanisms of Immune Signaling in Colitis-Associated Cancer. | Waldner MJ et al. | — | 2015 | → |
| Moderate activation of IKK2-NF-kB in unstressed adult mouse liver induces cytoprotective genes and lipogenesis without apparent signs of inflammation or fibrosis. | Lu H et al. | — | 2015 | → |
| Muscle wasting in disease: molecular mechanisms and promising therapies. | Cohen S et al. | — | 2015 | → |
| NF-κB downregulates Cbl-b through binding and suppressing Cbl-b promoter in T cell activation. | Liu Y et al. | — | 2015 | → |
| NF-κB in cancer therapy. | Li F et al. | — | 2015 | → |
| PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy. | Rojewska E et al. | — | 2015 | → |
| Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. | Blednov YA et al. | — | 2015 | → |
| Photoaffinity labeling of transcription factors by DNA-templated crosslinking. | Liu Y et al. | — | 2015 | → |
| Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury. | Tang H et al. | — | 2015 | → |
| Promoted Interaction of Nuclear Factor-κB With Demethylated Purinergic P2X3 Receptor Gene Contributes to Neuropathic Pain in Rats With Diabetes. | Zhang HH et al. | — | 2015 | → |
| Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate. | Krishnan RK et al. | — | 2015 | → |
| Quetiapine inhibits osteoclastogenesis and prevents human breast cancer-induced bone loss through suppression of the RANKL-mediated MAPK and NF-κB signaling pathways. | Wang H et al. | — | 2015 | → |
| Red Bean Extract Inhibits Lipopolysaccharide-Induced Inflammation and H₂O₂-Induced Oxidative Stress in RAW 264.7 Macrophages. | Chao WW et al. | — | 2015 | → |
| Regulation of NF-κB signaling in osteoclasts and myeloid progenitors. | Swarnkar G et al. | — | 2015 | → |
| Sesamin suppresses STZ induced INS-1 cell apoptosis through inhibition of NF-κB activation and regulation of Bcl-2 family protein expression. | Zheng S et al. | — | 2015 | → |
| S-Nitrosylation in TNF superfamily signaling pathway: Implication in cancer. | Plenchette S et al. | — | 2015 | → |
| TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes. | Möser CV et al. | — | 2015 | → |
| Tenuigenin inhibits RANKL-induced osteoclastogenesis by down-regulating NF-κB activation and suppresses bone loss in vivo. | Yang S et al. | — | 2015 | → |
| The anti-aging and tumor suppressor protein Klotho enhances differentiation of a human oligodendrocytic hybrid cell line. | Chen CD et al. | — | 2015 | → |
| Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes. | Barnes PJ | — | 2015 | → |
| The serum- & glucocorticoid-inducible kinase in the regulation of platelet function. | Lang F et al. | — | 2015 | → |
| To be an ally or an adversary in bladder cancer: the NF-κB story has not unfolded. | Mukherjee N et al. | — | 2015 | → |
| Tomato paste alters NF-κB and cancer-related mRNA expression in prostate cancer cells, xenografts, and xenograft microenvironment. | Kolberg M et al. | — | 2015 | → |
| 1-O-tigloyl-1-O-deacetyl-nimbolinin B inhibits LPS-stimulated inflammatory responses by suppressing NF-κB and JNK activation in microglia cells. | Tao L et al. | — | 2014 | → |
| 2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase. | Kuang S et al. | — | 2014 | → |
| Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats. | Wang YY et al. | — | 2014 | → |
| A novel IKKα inhibitor, noraristeromycin, blocks the chronic inflammation associated with collagen-induced arthritis in mice. | Ito M et al. | — | 2014 | → |
| Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches. | Jamal MS et al. | — | 2014 | → |
| Anti-inflammatory and analgesic effects of the marine-derived compound comaparvin isolated from the crinoid Comanthus bennetti. | Chen LC et al. | — | 2014 | → |
| A phase I clinical trial of systemically delivered NEMO binding domain peptide in dogs with spontaneous activated B-cell like diffuse large B-cell lymphoma. | Habineza Ndikuyeze G et al. | — | 2014 | → |
| Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells. | Wu DG et al. | — | 2014 | → |
| Association of TNF-α with impaired migration capacity of mesenchymal stem cells in patients with systemic lupus erythematosus. | Geng L et al. | — | 2014 | → |
| Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury. | Baeck C et al. | — | 2014 | → |
| Chemoprevention of head and neck squamous cell carcinoma through inhibition of NF-κB signaling. | Vander Broek R et al. | — | 2014 | → |
| Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism. | Pal S et al. | — | 2014 | → |
| Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development. | Swarnkar G et al. | — | 2014 | → |
| Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors. | Park CH et al. | — | 2014 | → |
| Effusanin E suppresses nasopharyngeal carcinoma cell growth by inhibiting NF-κB and COX-2 signaling. | Zhuang M et al. | — | 2014 | → |
| Fei-Liu-Ping ointment inhibits lung cancer growth and invasion by suppressing tumor inflammatory microenvironment. | Li W et al. | — | 2014 | → |
| Fentanyl increases colorectal carcinoma cell apoptosis by inhibition of NF-κB in a Sirt1-dependent manner. | Zhang XL et al. | — | 2014 | → |
| Four new bis-iridoids isolated from the traditional Tibetan herb Pterocephalus hookeri. | Wu YC et al. | — | 2014 | → |
| Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo. | Fakhrudin N et al. | — | 2014 | → |
| Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways. | Foo JB et al. | — | 2014 | → |
| Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids. | García-Rodríguez J et al. | — | 2014 | → |
| IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention. | Pazarentzos E et al. | — | 2014 | → |
| Lasiodin inhibits proliferation of human nasopharyngeal carcinoma cells by simultaneous modulation of the Apaf-1/caspase, AKT/MAPK and COX-2/NF-κB signaling pathways. | Lin L et al. | — | 2014 | → |
| Nanotechnology and glaucoma: a review of the potential implications of glaucoma nanomedicine. | Kim NJ et al. | — | 2014 | → |
| Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans. | Robinson G et al. | — | 2014 | → |
| Nuclear factor-kappa-B signaling in lung development and disease: one pathway, numerous functions. | Alvira CM | — | 2014 | → |
| PF-3758309, p21-activated kinase 4 inhibitor, suppresses migration and invasion of A549 human lung cancer cells via regulation of CREB, NF-κB, and β-catenin signalings. | Ryu BJ et al. | — | 2014 | → |
| PU-H71 effectively induces degradation of IκB kinase β in the presence of TNF-α. | Qu Z et al. | — | 2014 | → |
| Pulmonary toxicity in mice following exposure to cerium chloride. | Hong J et al. | — | 2014 | → |
| Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. | Yang C et al. | — | 2014 | → |
| Resources and biological activities of natural polyphenols. | Li AN et al. | — | 2014 | → |
| Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors. | Han S et al. | — | 2014 | → |
| Signaling pathways in cartilage repair. | Mariani E et al. | — | 2014 | → |
| Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of nuclear factor-κB. | Kato Y et al. | — | 2014 | → |
| Synthesis and in vitro characterization of ionone-based compounds as dual inhibitors of the androgen receptor and NF-κB. | Liu W et al. | — | 2014 | → |
| Taming inflammation by targeting cytokine signaling: new perspectives in the induction of transplantation tolerance. | Khalifian S et al. | — | 2014 | → |
| Tamoxifen reduces infiltration of inflammatory cells, apoptosis and inhibits IKK/NF-kB pathway after spinal cord injury in rats. | Wei HY et al. | — | 2014 | → |
| The role of NF-κB in the pathogenesis of glioma. | Puliyappadamba VT et al. | — | 2014 | → |
| The role of oxidative stress during inflammatory processes. | Lugrin J et al. | — | 2014 | → |
| The study of mechanisms of protective effect of Rg1 against arthritis by inhibiting osteoclast differentiation and maturation in CIA mice. | Gu Y et al. | — | 2014 | → |
| Thioredoxin-mediated denitrosylation regulates cytokine-induced nuclear factor κB (NF-κB) activation. | Kelleher ZT et al. | — | 2014 | → |
| α-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-κB signalling. | Piao HL et al. | — | 2014 | → |
| α-catenin. A tumor suppressor beyond adherens junctions. | Sun Y et al. | — | 2014 | → |
| Adamantyl arotinoids that inhibit IκB kinase α and IκB kinase β. | Lorenzo P et al. | — | 2013 | → |
| AhR- and NF-κB-dependent induction of interleukin-6 by co-exposure to the environmental contaminant benzanthracene and the cytokine tumor necrosis factor-α in human mammary MCF-7 cells. | Kolasa E et al. | — | 2013 | → |
| An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. | Reilly SM et al. | — | 2013 | → |
| A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages. | González Y et al. | — | 2013 | → |
| A redox economical synthesis of bioactive 6,12-guaianolides. | Wen B et al. | — | 2013 | → |
| Beyond NF-κB activation: nuclear functions of IκB kinase α. | Huang WC et al. | — | 2013 | → |
| Butein inhibits NF-κB activation and reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. | Lu M et al. | — | 2013 | → |
| Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms. | Peng YM et al. | — | 2013 | → |
| CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction. | Venkatesan B et al. | — | 2013 | → |
| Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway. | Qu Z et al. | — | 2013 | → |
| Crystal structure and mechanism of activation of TANK-binding kinase 1. | Larabi A et al. | — | 2013 | → |
| Dalesconols B inhibits lipopolysaccharide induced inflammation and suppresses NF-κB and p38/JNK activation in microglial cells. | Han L et al. | — | 2013 | → |
| Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts. | Purdom E et al. | — | 2013 | → |
| Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanisms explaining in part Chinese herbal theory "Junn-Chenn-Zuou-SS". | Ho LJ et al. | — | 2013 | → |
| Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes. | Ku CS et al. | — | 2013 | → |
| (-)-Epigallocatechin gallate amplifies interleukin-1-stimulated interleukin-6 synthesis in osteoblast-like MC3T3-E1 cells. | Kuroyanagi G et al. | — | 2013 | → |
| Epigenetic control of NF-κB-dependent FAS gene transcription during progression of myelodysplastic syndromes. | Ettou S et al. | — | 2013 | → |
| Ethanol extract of Adiantum capillus-veneris L. suppresses the production of inflammatory mediators by inhibiting NF-κB activation. | Yuan Q et al. | — | 2013 | → |
| Ethnopharmacological in vitro studies on Austria's folk medicine--an unexplored lore in vitro anti-inflammatory activities of 71 Austrian traditional herbal drugs. | Vogl S et al. | — | 2013 | → |
| Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. | Jayakumar T et al. | — | 2013 | → |
| Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia. | Ali S et al. | — | 2013 | → |
| Hit identification of IKKβ natural product inhibitor. | Leung CH et al. | — | 2013 | → |
| Influence of inflammatory pathway markers on oxidative stress induced by cold stress in intestine of quails. | Fu J et al. | — | 2013 | → |
| Inhibition of SAPK/JNK leads to enhanced IL-1-induced IL-6 synthesis in osteoblasts. | Kondo A et al. | — | 2013 | → |
| Inhibitory effect of carbazolequinone derivatives on lipopolysaccharide and interferon-γ-induced nitric oxide production in mouse macrophage RAW264.7 cells. | Murata T et al. | — | 2013 | → |
| Interleukin-6 upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway. | Cheng CC et al. | — | 2013 | → |
| IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. | Seufert BL et al. | — | 2013 | → |
| Lipopolysaccharides reduce adipogenesis in 3T3-L1 adipocytes through activation of NF-κB pathway and downregulation of AMPK expression. | Wang L et al. | — | 2013 | → |
| Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes. | de Andrés MC et al. | — | 2013 | → |
| MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation. | Hwang YJ et al. | — | 2013 | → |
| Matrine effectively inhibits the proliferation of breast cancer cells through a mechanism related to the NF-κB signaling pathway. | Shao H et al. | — | 2013 | → |
| miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. | Cai J et al. | — | 2013 | → |
| Modulators of HIF1α and NFkB in Cancer Treatment: Is it a Rational Approach for Controlling Malignant Progression? | Tafani M et al. | — | 2013 | → |
| Molecular docking and synthesis of novel quinazoline analogues as inhibitors of transcription factors NF-κB activation and their anti-cancer activities. | Xu L et al. | — | 2013 | → |
| Natural products as promising drug candidates for the treatment of Alzheimer's disease: molecular mechanism aspect. | Ansari N et al. | — | 2013 | → |
| NFκB function and regulation in cutaneous T-cell lymphoma. | Chang TP et al. | — | 2013 | → |
| NF-κB p65/p52 plays a role in GDNF up-regulating Bcl-2 and Bcl-w expression in 6-OHDA-induced apoptosis of MN9D cell. | Cao JP et al. | — | 2013 | → |
| NF-κB RNAi decreases the Bax/Bcl-2 ratio and inhibits TNF-α-induced apoptosis in human alveolar epithelial cells. | Li L et al. | — | 2013 | → |
| NF-κB signaling and bone resorption. | Abu-Amer Y | — | 2013 | → |
| NF-κB-targeted anti-inflammatory activity of Prunella vulgaris var. lilacina in macrophages RAW 264.7. | Hwang YJ et al. | — | 2013 | → |
| Norisoboldine suppresses osteoclast differentiation through preventing the accumulation of TRAF6-TAK1 complexes and activation of MAPKs/NF-κB/c-Fos/NFATc1 Pathways. | Wei ZF et al. | — | 2013 | → |
| Oncosuppressive suicide gene virotherapy "PVH1-yCD/5-FC" for pancreatic peritoneal carcinomatosis treatment: NFκB and Akt/PI3K involvement. | Réjiba S et al. | — | 2013 | → |
| P97/CDC-48: proteostasis control in tumor cell biology. | Fessart D et al. | — | 2013 | → |
| Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy. | Ganesh Yerra V et al. | — | 2013 | → |
| Principles of liver regeneration and growth homeostasis. | Michalopoulos GK | — | 2013 | → |
| Prolongation of rat renal allograft survival by CD4⁺CD25⁻ T cells induced by recipient dendritic cells transfected with IKK2dn. | Wang S et al. | — | 2013 | → |
| Proteomics and NF-κB: an update. | Niederberger E et al. | — | 2013 | → |
| Resolution of inflammation: mechanisms and opportunity for drug development. | Alessandri AL et al. | — | 2013 | → |
| Role of lysine methylation of NF-κB in differential gene regulation. | Lu T et al. | — | 2013 | → |
| SC-514, a selective inhibitor of IKKβ attenuates RANKL-induced osteoclastogenesis and NF-κB activation. | Liu Q et al. | — | 2013 | → |
| Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKK β Activity and JNK Phosphorylation. | Li T et al. | — | 2013 | → |
| Simvastatin induces apoptosis in castrate resistant prostate cancer cells by deregulating nuclear factor-κB pathway. | Park YH et al. | — | 2013 | → |
| Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases. | Llona-Minguez S et al. | — | 2013 | → |
| SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC. | Yang ST et al. | — | 2013 | → |
| Surgical removal of endometrioma decreases the NF-kB1 (p50/105) and NF-kB p65 (Rel A) expression in the eutopic endometrium during the implantation window. | Celik O et al. | — | 2013 | → |
| Targeting apoptosis pathways in pancreatic cancer. | Arlt A et al. | — | 2013 | → |
| Targeting the tumor microenvironment: from understanding pathways to effective clinical trials. | Fang H et al. | — | 2013 | → |
| The nuclear factor-κB pathway down-regulates expression of the NKG2D ligand H60a in vitro: implications for use of nuclear factor-κB inhibitors in cancer therapy. | Peinado C et al. | — | 2013 | → |
| The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo. | Ito K et al. | — | 2013 | → |
| The role of interleukin 1β in the anti-adipogenic action of macrophages on human preadipocytes. | Gagnon A et al. | — | 2013 | → |
| Toll-like receptor signaling in neonatal sepsis and inflammation: a matter of orchestration and conditioning. | Glaser K et al. | — | 2013 | → |
| Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis. | Zhang Y et al. | — | 2013 | → |
| Vitamin C forestalls cigarette smoke induced NF-κB activation in alveolar epithelial cells. | Das B et al. | — | 2013 | → |
| 1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes. | Lee HY et al. | — | 2012 | → |
| 3-Phenylcoumarins as inhibitors of HIV-1 replication. | Olmedo D et al. | — | 2012 | → |
| 4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacy. | Liddle J et al. | — | 2012 | → |
| 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. | Ha SK et al. | — | 2012 | → |
| Activity of tumor necrosis factor-α blocked by phytoglycoprotein (38 kDa) at initiation stage in N-nitrosodiethylamine-induced ICR mice. | Lee J et al. | — | 2012 | → |
| AMPK limits IL-1-stimulated IL-6 synthesis in osteoblasts: involvement of IκB/NF-κB pathway. | Kato K et al. | — | 2012 | → |
| Analysing the role of UVB-induced translational inhibition and PP2Ac deactivation in NF-κB signalling using a minimal mathematical model. | Witt J et al. | — | 2012 | → |
| Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases. | Švajger U et al. | — | 2012 | → |
| Anti-inflammatory flavonoids from Cryptocarya chingii. | Feng R et al. | — | 2012 | → |
| Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling. | Hexum JK et al. | — | 2012 | → |
| Biphasic activation of nuclear factor-kappa B in experimental models of subarachnoid hemorrhage in vivo and in vitro. | You WC et al. | — | 2012 | → |
| Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans. | Hasegawa Y et al. | — | 2012 | → |
| Constitutive over expression of IL-1β, IL-6, NF-κB, and Stat3 is a potential cause of lung tumorgenesis in urethane (ethyl carbamate) induced Balb/c mice. | Narayan C et al. | — | 2012 | → |
| Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis. | Jin HR et al. | — | 2012 | → |
| Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling. | Minelli A et al. | — | 2012 | → |
| Deguelin, an Akt inhibitor, down-regulates NF-κB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice. | Kang HW et al. | — | 2012 | → |
| Discovery of potent and selective rhodanine type IKKβ inhibitors by hit-to-lead strategy. | Song H et al. | — | 2012 | → |
| Drug resistance in glioblastoma: a mini review. | Haar CP et al. | — | 2012 | → |
| Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes. | Vanden Berghe W | — | 2012 | → |
| ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK. | Tam AB et al. | — | 2012 | → |
| Ethanol extract of Graptopetalum paraguayense upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway. | Cheng CC et al. | — | 2012 | → |
| Functional characterization of mammalian Wntless homolog in mammalian system. | Wang LT et al. | — | 2012 | → |
| IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model. | von Bismarck P et al. | — | 2012 | → |
| Inhibitor kappa B kinase beta dependent cytokine upregulation in nociceptive neurons contributes to nociceptive hypersensitivity after sciatic nerve injury. | Kanngiesser M et al. | — | 2012 | → |
| Insertion of a nuclear factor kappa B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines. | Cramer F et al. | — | 2012 | → |
| IκB kinase regulation of the TPL-2/ERK MAPK pathway. | Gantke T et al. | — | 2012 | → |
| IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells. | Lupino E et al. | — | 2012 | → |
| Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. | Matta H et al. | — | 2012 | → |
| Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation. | Cuadrado I et al. | — | 2012 | → |
| Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis. | Alhawagri M et al. | — | 2012 | → |
| Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients. | Lin L et al. | — | 2012 | → |
| Metastasis suppressors in human benign prostate, intraepithelial neoplasia, and invasive cancer: their prospects as therapeutic agents. | Khamis ZI et al. | — | 2012 | → |
| MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKKβ/NF-κB pathway and reduced interleukin-8 expression. | Dai L et al. | — | 2012 | → |
| miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1. | Amodio N et al. | — | 2012 | → |
| Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. | Johnson TA et al. | — | 2012 | → |
| NF-κB and the link between inflammation and cancer. | DiDonato JA et al. | — | 2012 | → |
| NF-κB as a potential therapeutic target in microbial diseases. | Vitiello M et al. | — | 2012 | → |
| Norisoboldine inhibits the production of interleukin-6 in fibroblast-like synoviocytes from adjuvant arthritis rats through PKC/MAPK/NF-κB-p65/CREB pathways. | Wei Z et al. | — | 2012 | → |
| Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor. | Alam A et al. | — | 2012 | → |
| Nuclear factor-kappaB: a main regulator of inflammation and cell survival in endometriosis pathophysiology. | González-Ramos R et al. | — | 2012 | → |
| Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients. | González-Ramos R et al. | — | 2012 | → |
| Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. | Ouyang L et al. | — | 2012 | → |
| Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model. | Xia Y et al. | — | 2012 | → |
| Role of T-cell-specific nuclear factor κB in islet allograft rejection. | Porras DL et al. | — | 2012 | → |
| Role of β2-adrenoceptor-β-arrestin2-nuclear factor-κB signal transduction pathway and intervention effects of oxymatrine in ulcerative colitis. | Fan H et al. | — | 2012 | → |
| Severe asthma: advances in current management and future therapy. | Barnes PJ | — | 2012 | → |
| Suppression of NF-κB and NF-κB regulated oxidative stress and neuroinflammation by BAY 11-7082 (IκB phosphorylation inhibitor) in experimental diabetic neuropathy. | Kumar A et al. | — | 2012 | → |
| Suppression of TLR signaling by targeting TIR domain-containing proteins. | Fekonja O et al. | — | 2012 | → |
| Targeting activation of specific NF-κB subunits prevents stress-dependent atherothrombotic gene expression. | Djuric Z et al. | — | 2012 | → |
| Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. | Han X et al. | — | 2012 | → |
| The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma. | Reber LL et al. | — | 2012 | → |
| The diverse and complex roles of NF-κB subunits in cancer. | Perkins ND | — | 2012 | → |
| The myxobacterial compounds spirangien a and spirangien M522 are potent inhibitors of IL-8 expression. | Reboll MR et al. | — | 2012 | → |
| The pharmacological NF-κB inhibitor BAY11-7082 induces cell apoptosis and inhibits the migration of human uveal melanoma cells. | Hu S et al. | — | 2012 | → |
| Therapeutic potential of the proteasome inhibitor Bortezomib on titanium particle-induced inflammation in a murine model. | Mao X et al. | — | 2012 | → |
| The serum- and glucocorticoid-inducible kinase 1 (SGK1) influences platelet calcium signaling and function by regulation of Orai1 expression in megakaryocytes. | Borst O et al. | — | 2012 | → |
| Two new glycosidated coumaramides from Clerodendron cyrtophyllum. | Wang P et al. | — | 2012 | → |
| γ-Tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes. | Matsunaga T et al. | — | 2012 | → |
| 3,5-Disubstituted-indole-7-carboxamides: the discovery of a novel series of potent, selective inhibitors of IKK-β. | Miller DD et al. | — | 2011 | → |
| 3D QSAR pharmacophore model based on diverse IKKβ inhibitors. | Nagarajan S et al. | — | 2011 | → |
| Advances in the understanding of mechanisms and therapeutic use of bortezomib. | Mujtaba T et al. | — | 2011 | → |
| Akt fine-tunes NF-κB-dependent gene expression during T cell activation. | Cheng J et al. | — | 2011 | → |
| Akt-mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism. | Cremer TJ et al. | — | 2011 | → |
| Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship. | Xie J et al. | — | 2011 | → |
| A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit. | Cushing TD et al. | — | 2011 | → |
| Blocking IKKα expression inhibits prostate cancer invasiveness. | Mahato R et al. | — | 2011 | → |
| Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. | Chen D et al. | — | 2011 | → |
| Characterisation and manipulation of docetaxel resistant prostate cancer cell lines. | O'Neill AJ et al. | — | 2011 | → |
| Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it. | Sun HP et al. | — | 2011 | → |
| Cucurbitacin B suppresses the transactivation activity of RelA/p65. | Jin HR et al. | — | 2011 | → |
| Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy. | Williams PD et al. | — | 2011 | → |
| Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet. | Tobar N et al. | — | 2011 | → |
| Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques. | Noha SM et al. | — | 2011 | → |
| Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo. | Shimizu H et al. | — | 2011 | → |
| Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: exploration of effective compounds in arthritis models. | Shimizu H et al. | — | 2011 | → |
| Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors. | Kim S et al. | — | 2011 | → |
| Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors. | Dai Y et al. | — | 2011 | → |
| Emerging roles for the non-canonical IKKs in cancer. | Shen RR et al. | — | 2011 | → |
| Evidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO. | Dai S et al. | — | 2011 | → |
| Evolutionary conserved regulation of HIF-1β by NF-κB. | van Uden P et al. | — | 2011 | → |
| Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-κB pathway in rat aorta. | Li H et al. | — | 2011 | → |
| Future forms of immunotherapy and immunomodulators in allergic disease. | Nguyen TH et al. | — | 2011 | → |
| Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity. | Sala E et al. | — | 2011 | → |
| Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays. | Sala E et al. | — | 2011 | → |
| Identifying and testing potential new anti-asthma agents. | Fang C et al. | — | 2011 | → |
| Immunomodulatory activity of dietary fiber: arabinoxylan and mixed-linked beta-glucan isolated from barley show modest activities in vitro. | Samuelsen AB et al. | — | 2011 | → |
| Inhibition of HIF prolyl hydroxylase-2 blocks tumor growth in mice through the antiproliferative activity of TGFβ. | Klotzsche-von Ameln A et al. | — | 2011 | → |
| Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo. | Pinto R et al. | — | 2011 | → |
| Inhibition of NF-κB signaling as a strategy in disease therapy. | Gilmore TD et al. | — | 2011 | → |
| Inhibition of TNF-α-mediated inflammatory responses by a benzodioxolylacetylamino-linked benzothiazole analog in human fibroblast-like synoviocytes. | Lee YR et al. | — | 2011 | → |
| Involvement of visfatin in palmitate-induced upregulation of inflammatory cytokines in hepatocytes. | Choi YJ et al. | — | 2011 | → |
| Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells. | Mi L et al. | — | 2011 | → |
| JSH-23 targets nuclear factor-kappa B and reverses various deficits in experimental diabetic neuropathy: effect on neuroinflammation and antioxidant defence. | Kumar A et al. | — | 2011 | → |
| Lipid-heparin infusion suppresses the IL-10 response to trauma in subcutaneous adipose tissue in humans. | Ikeoka DT et al. | — | 2011 | → |
| LITAF mediation of increased TNF-α secretion from inflamed colonic lamina propria macrophages. | Bushell KN et al. | — | 2011 | → |
| LRP16 integrates into NF-κB transcriptional complex and is required for its functional activation. | Wu Z et al. | — | 2011 | → |
| Maintenance of IKKβ activity is necessary to protect lung grafts from acute injury. | Huang HJ et al. | — | 2011 | → |
| Mapping of NRF binding motifs of NF-kappaB p65 subunit. | Reboll MR et al. | — | 2011 | → |
| Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses. | Tao W et al. | — | 2011 | → |
| Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades. | Negi G et al. | — | 2011 | → |
| NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target. | Chen W et al. | — | 2011 | → |
| Personalized cancer approach: using RNA interference technology. | Nemunaitis J et al. | — | 2011 | → |
| Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. | Xie HZ et al. | — | 2011 | → |
| Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii. | Wu CS et al. | — | 2011 | → |
| Radiation induced non-targeted response: mechanism and potential clinical implications. | Hei TK et al. | — | 2011 | → |
| Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. | Xue W et al. | — | 2011 | → |
| Rethinking the metastatic cascade as a therapeutic target. | Mina LA et al. | — | 2011 | → |
| RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway. | Shimada K et al. | — | 2011 | → |
| Sensitivity and gene expression profile of fresh human acute myeloid leukemia cells exposed ex vivo to AS602868. | Jordheim LP et al. | — | 2011 | → |
| Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. | Zhou W et al. | — | 2011 | → |
| Small-molecule-based nanoassemblies as inducible nanoprobes for monitoring dynamic molecular interactions inside live cells. | Lee S et al. | — | 2011 | → |
| Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β. | Avila CM et al. | — | 2011 | → |
| Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents. | De Jonghe S et al. | — | 2011 | → |
| Terminalia chebula extract acts as a potential NF-κB inhibitor in human lymphoblastic T cells. | Das ND et al. | — | 2011 | → |
| The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. | Ahmed N et al. | — | 2011 | → |
| The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma. | Gunn EJ et al. | — | 2011 | → |
| The protein kinase IKKε is a potential target for the treatment of inflammatory hyperalgesia. | Möser CV et al. | — | 2011 | → |
| TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis. | Mankan AK et al. | — | 2011 | → |
| Triggering of Toll-like Receptor-2 in Mouse Myelomonocytic Leukaemia Cells WEHI-3B Leads to the Suppression of Apoptosis and Promotes Tumor Progression in Vivo. | Shcheblyakov DV et al. | — | 2011 | → |
| 17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition. | Hertlein E et al. | — | 2010 | → |
| Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation. | Langereis JD et al. | — | 2010 | → |
| Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression. | Rothgiesser KM et al. | — | 2010 | → |
| Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer. | Hernandez L et al. | — | 2010 | → |
| A formal model for analyzing drug combination effects and its application in TNF-alpha-induced NFkappaB pathway. | Yan H et al. | — | 2010 | → |
| A homogeneous time-resolved fluorescence-based high-throughput screening system for discovery of inhibitors of IKKbeta-NEMO interaction. | Gotoh Y et al. | — | 2010 | → |
| Analysis of NF-kappaB signaling pathways by proteomic approaches. | Niederberger E et al. | — | 2010 | → |
| A novel anticancer agent, retigeric acid B, displays proliferation inhibition, S phase arrest and apoptosis activation in human prostate cancer cells. | Liu H et al. | — | 2010 | → |
| Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition. | Chao WW et al. | — | 2010 | → |
| Apple, cherry, and blackcurrant increases nuclear factor kappa B activation in liver of transgenic mice. | Balstad TR et al. | — | 2010 | → |
| Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin. | Momeny M et al. | — | 2010 | → |
| Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma. | Lauscher JC et al. | — | 2010 | → |
| Bcl-2 is a negative regulator of interleukin-1beta secretion in murine macrophages in pharmacological-induced apoptosis. | Escandell JM et al. | — | 2010 | → |
| Can your genes make you more prone to pneumococcal disease? | Chapman SJ | — | 2010 | → |
| Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery. | Ye H et al. | — | 2010 | → |
| Chemopreventive potential of natural compounds in head and neck cancer. | Rahman MA et al. | — | 2010 | → |
| Chronic obstructive pulmonary disease: an update of treatment related to frequently associated comorbidities. | Sinden NJ et al. | — | 2010 | → |
| Chrysin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells via suppression of nuclear factor-kappaB. | Li X et al. | — | 2010 | → |
| Combination of photodynamic therapy with aspirin in human-derived lung adenocarcinoma cells affects proteasome activity and induces apoptosis. | Chiaviello A et al. | — | 2010 | → |
| Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. | Chapman SJ et al. | — | 2010 | → |
| Current views of toll-like receptor signaling pathways. | Yamamoto M et al. | — | 2010 | → |
| Degree of roasting is the main determinant of the effects of coffee on NF-kappaB and EpRE. | Paur I et al. | — | 2010 | → |
| Discovery of imidazo[1,2-b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit-to-lead study and structure-activity relationship. | Shimizu H et al. | — | 2010 | → |
| Donor antigen-loaded IKK2dn gene-modified dendritic cells prolong allograft survival. | Ouyang J et al. | — | 2010 | → |
| Drug-mediated and cellular immunotherapy in multiple myeloma. | Ritchie DS et al. | — | 2010 | → |
| Expression of classical NF-kappaB pathway effectors in human ovarian carcinoma. | Darb-Esfahani S et al. | — | 2010 | → |
| Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. | Zhou P et al. | — | 2010 | → |
| High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines. | Bartfeld S et al. | — | 2010 | → |
| High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay. | Bhattacharya N et al. | — | 2010 | → |
| Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway. | Rosato RR et al. | — | 2010 | → |
| Human kinome drug discovery and the emerging importance of atypical allosteric inhibitors. | Eglen RM et al. | — | 2010 | → |
| Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. | Miller SC et al. | — | 2010 | → |
| I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma. | Al-Katib A et al. | — | 2010 | → |
| IKK-beta inhibitors: an analysis of drug-receptor interaction by using molecular docking and pharmacophore 3D-QSAR approaches. | Lauria A et al. | — | 2010 | → |
| Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation. | Lee SY et al. | — | 2010 | → |
| In CD28-costimulated human naïve CD4+ T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms. | Lupino E et al. | — | 2010 | → |
| Induction of laryngeal cancer cell death by Ent-11-hydroxy-15-oxo-kaur-16-en-19-oic acid. | Vlantis AC et al. | — | 2010 | → |
| Inhibiting NF-κB activation by small molecules as a therapeutic strategy. | Gupta SC et al. | — | 2010 | → |
| Inhibition of nuclear factor kappaB activation and cyclooxygenase-2 expression by aqueous extracts of Hispanic medicinal herbs. | Orlando RA et al. | — | 2010 | → |
| Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion. | Bauerle KT et al. | — | 2010 | → |
| Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis. | González-Ramos R et al. | — | 2010 | → |
| MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages. | Premkumar V et al. | — | 2010 | → |
| Natural products inhibit LPS-induced activation of pro-inflammatory cytokines in peripheral blood mononuclear cells. | Shah VO et al. | — | 2010 | → |
| Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. | Szarc vel Szic K et al. | — | 2010 | → |
| Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation. | Kaus A et al. | — | 2010 | → |
| New therapies for asthma: is there any progress? | Barnes PJ | — | 2010 | → |
| NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS. | Harris TH et al. | — | 2010 | → |
| NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways. | Amschler K et al. | — | 2010 | → |
| NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy. | Kumar A et al. | — | 2010 | → |
| NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia. | Breccia M et al. | — | 2010 | → |
| NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis. | Maeda S | — | 2010 | → |
| Novel findings in drug-induced dendritic cell tolerogenicity. | Svajger U et al. | — | 2010 | → |
| Nuclear factor kappaB controls acetylcholine receptor clustering at the neuromuscular junction. | Wang J et al. | — | 2010 | → |
| Oncogenic activation of NF-kappaB. | Staudt LM | — | 2010 | → |
| Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells. | Ahmed M et al. | — | 2010 | → |
| Pharmacological strategies for improving the efficacy and therapeutic ratio of glucocorticoids in inflammatory lung diseases. | Newton R et al. | — | 2010 | → |
| Platonin improves survival of skin allografts. | Cheng SP et al. | — | 2010 | → |
| Radiation-induced bystander signaling pathways in human fibroblasts: a role for interleukin-33 in the signal transmission. | Ivanov VN et al. | — | 2010 | → |
| Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. | Lu T et al. | — | 2010 | → |
| Ruscogenin mainly inhibits nuclear factor-kappaB but not Akt and mitogen-activated protein kinase signaling pathways in human umbilical vein endothelial cells. | Song J et al. | — | 2010 | → |
| Signalling to drug resistance in CLL. | Hertlein E et al. | — | 2010 | → |
| Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia. | Liu S et al. | — | 2010 | → |
| Targeting kinases for the treatment of inflammatory diseases. | Müller S et al. | — | 2010 | → |
| Targeting NF-kappaB for colorectal cancer. | Sakamoto K et al. | — | 2010 | → |
| Targeting NF-κB in infantile hemangioma-derived stem cells reduces VEGF-A expression. | Greenberger S et al. | — | 2010 | → |
| The anti-inflammatory and antinociceptive effects of NF-kappaB inhibitory guanidine derivative ME10092. | Dambrova M et al. | — | 2010 | → |
| The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes. | Elsharkawy AM et al. | — | 2010 | → |
| The resolution of inflammation: anti-inflammatory roles for NF-kappaB. | Lawrence T et al. | — | 2010 | → |
| Toll-Like Receptors (TLRs): The Role in Tumor Progression. | Shcheblyakov DV et al. | — | 2010 | → |
| Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis. | Jager J et al. | — | 2010 | → |
| Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis. | Darwech I et al. | — | 2010 | → |
| 20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes. | Janjetovic Z et al. | — | 2009 | → |
| 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors. | Liddle J et al. | — | 2009 | → |
| A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits". | Kang MI et al. | — | 2009 | → |
| Assessing medicinal plants from South-Eastern Spain for potential anti-inflammatory effects targeting nuclear factor-Kappa B and other pro-inflammatory mediators. | Bremner P et al. | — | 2009 | → |
| ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia. | Grosjean-Raillard J et al. | — | 2009 | → |
| BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis. | Liu P et al. | — | 2009 | → |
| Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate. | Li X et al. | — | 2009 | → |
| Change in markers of bone metabolism with chemotherapy for advanced prostate cancer: interleukin-6 response is a potential early indicator of response to therapy. | Ignatoski KM et al. | — | 2009 | → |
| Chemopreventive action of Lygodium flexuosum extract in human hepatoma PLC/PRF/5 and Hep 3B cells. | Wills PJ et al. | — | 2009 | → |
| Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade. | Jin X et al. | — | 2009 | → |
| cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation. | Jin HS et al. | — | 2009 | → |
| Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth. | Sakamoto K et al. | — | 2009 | → |
| Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells. | Wharry CE et al. | — | 2009 | → |
| Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated I kappaB kinase. | von Metzler I et al. | — | 2009 | → |
| Design and synthesis of backbone cyclic phosphorylated peptides: The IkappaB model. | Qvit N et al. | — | 2009 | → |
| Direct Rel/NF-κB inhibitors: structural basis for mechanism of action. | Ouk S et al. | — | 2009 | → |
| Discovery of 6-aryl-7-alkoxyisoquinoline inhibitors of IkappaB kinase-beta (IKK-beta). | Christopher JA et al. | — | 2009 | → |
| Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling. | Aldridge BB et al. | — | 2009 | → |
| Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades. | Yang Z et al. | — | 2009 | → |
| Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer. | Tas SW et al. | — | 2009 | → |
| Glucocorticoid resistance in inflammatory diseases. | Barnes PJ et al. | — | 2009 | → |
| Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode. | Qian K et al. | — | 2009 | → |
| Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response. | Karl S et al. | — | 2009 | → |
| Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression. | Maeda S et al. | — | 2009 | → |
| IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening. | Nagarajan S et al. | — | 2009 | → |
| Impediment of NEMO oligomerization inhibits osteoclastogenesis and osteolysis. | Darwech I et al. | — | 2009 | → |
| Inflammation, cancer, and bone loss. | Abu-Amer Y | — | 2009 | → |
| Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-kappaB activity by glucocorticoids. | Bladh LG et al. | — | 2009 | → |
| Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity. | Bockhart V et al. | — | 2009 | → |
| In vivo pharmacodynamic imaging of proteasome inhibition. | Kimbrel EA et al. | — | 2009 | → |
| Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. | Baud V et al. | — | 2009 | → |
| Lornoxicam suppresses recurrent herpetic stromal keratitis through down-regulation of nuclear factor-kappaB: an experimental study in mice. | Yin J et al. | — | 2009 | → |
| Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes. | Yamaura M et al. | — | 2009 | → |
| Management of bladder cancer: current and emerging strategies. | Agarwal N et al. | — | 2009 | → |
| Mechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach. | Witt J et al. | — | 2009 | → |
| MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. | Li Y et al. | — | 2009 | → |
| Mustard NPR1, a mammalian IkappaB homologue inhibits NF-kappaB activation in human GBM cell lines. | Kesanakurti D et al. | — | 2009 | → |
| Natural and synthetic α,β-unsaturated carbonyls for NF-κB inhibition. | Ramachandran PV et al. | — | 2009 | → |
| NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation. | Solt LA et al. | — | 2009 | → |
| Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system. | Emmanouil M et al. | — | 2009 | → |
| NF-kappaB modulators in osteolytic bone diseases. | Xu J et al. | — | 2009 | → |
| NF-kappaB regulation: the nuclear response. | Mankan AK et al. | — | 2009 | → |
| NF-kappaB signaling in cerebral ischemia. | Ridder DA et al. | — | 2009 | → |
| Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo. | Zhang D et al. | — | 2009 | → |
| Old target new approach: an alternate NF-kappaB activation pathway via translation inhibition. | László CF et al. | — | 2009 | → |
| Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma. | Badros A et al. | — | 2009 | → |
| Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells. | Liu D et al. | — | 2009 | → |
| Potential pharmacological control of the NF-κB pathway. | Sethi G et al. | — | 2009 | → |
| Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage. | Kilareski EM et al. | — | 2009 | → |
| Retinoic acid dampens LPS-induced NF-kappaB activity: results from human monoblasts and in vivo imaging of NF-kappaB reporter mice. | Austenaa LM et al. | — | 2009 | → |
| Roles of NF-kappaB in health and disease: mechanisms and therapeutic potential. | Wong ET et al. | — | 2009 | → |
| Sensitization of neuroblastoma cells for TRAIL-induced apoptosis by NF-kappaB inhibition. | Ammann JU et al. | — | 2009 | → |
| siRNA vs. shRNA: similarities and differences. | Rao DD et al. | — | 2009 | → |
| SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. | Kawahara TL et al. | — | 2009 | → |
| Systemic manifestations and comorbidities of COPD. | Barnes PJ et al. | — | 2009 | → |
| Targeting the DNA damage response in cancer. | Ljungman M | — | 2009 | → |
| Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. | Edwards MR et al. | — | 2009 | → |
| The current status of drug discovery against the human kinome. | Eglen RM et al. | — | 2009 | → |
| The inhibition of TNF-alpha-induced NF-kappaB activation by marine natural products. | Folmer F et al. | — | 2009 | → |
| The nuclear factor NF-kappaB pathway in inflammation. | Lawrence T | — | 2009 | → |
| Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death. | Pritchard JR et al. | — | 2009 | → |
| Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. | Lu T et al. | — | 2009 | → |
| 17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells. | Yan SS et al. | — | 2008 | → |
| A cyclopentanediol analogue selectively suppresses the conserved innate immunity pathways, Drosophila IMD and TNF-alpha pathways. | Sekiya M et al. | — | 2008 | → |
| An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. | Fong CH et al. | — | 2008 | → |
| Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks. | Uwe S | — | 2008 | → |
| Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia. | Liu S et al. | — | 2008 | → |
| Cell penetrating peptide inhibitors of nuclear factor-kappa B. | Orange JS et al. | — | 2008 | → |
| Chemoprevention by white currant is mediated by the reduction of nuclear beta-catenin and NF-kappaB levels in Min mice adenomas. | Rajakangas J et al. | — | 2008 | → |
| c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. | Wolter S et al. | — | 2008 | → |
| Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. | Prakash S et al. | — | 2008 | → |
| Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. | Lam LT et al. | — | 2008 | → |
| Cordyceps: a traditional Chinese medicine and another fungal therapeutic biofactory? | Paterson RR | — | 2008 | → |
| Dynamic protein complexes regulate NF-kappaB signaling. | Wegener E et al. | — | 2008 | → |
| Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunities. | Plati J et al. | — | 2008 | → |
| Extracts of dietary plants are efficient modulators of nuclear factor kappa B. | Paur I et al. | — | 2008 | → |
| Fifty years of Biochemical Pharmacology: the discipline and the journal. | Enna SJ et al. | — | 2008 | → |
| Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia. | Grosjean-Raillard J et al. | — | 2008 | → |
| G protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer. | Fraser CC | — | 2008 | → |
| GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice. | Hirose K et al. | — | 2008 | → |
| Heparan sulfate domains on cultured activated glomerular endothelial cells mediate leukocyte trafficking. | Rops AL et al. | — | 2008 | → |
| High-affinity interaction between IKKbeta and NEMO. | Lo YC et al. | — | 2008 | → |
| High-throughput cellular assays for regulated posttranslational modifications. | Robers MB et al. | — | 2008 | → |
| Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: its inhibition by UVB turns NF-kappaB into a pro-apoptotic factor. | Barisic S et al. | — | 2008 | → |
| IkappaB kinase beta (IKKbeta/IKK2/IKBKB)--a key molecule in signaling to the transcription factor NF-kappaB. | Schmid JA et al. | — | 2008 | → |
| IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells. | Böcker W et al. | — | 2008 | → |
| Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. | Domingo-Domènech J et al. | — | 2008 | → |
| Inducible IL-23p19 expression in human microglia via p38 MAPK and NF-kappaB signal pathways. | Li Y et al. | — | 2008 | → |
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. | Lorenzo P et al. | — | 2008 | → |
| Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis. | Sheu ML et al. | — | 2008 | → |
| KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment. | Schön M et al. | — | 2008 | → |
| Marine natural products as targeted modulators of the transcription factor NF-kappaB. | Folmer F et al. | — | 2008 | → |
| Mechanisms of Cdc48/VCP-mediated cell death: from yeast apoptosis to human disease. | Braun RJ et al. | — | 2008 | → |
| Metabolism and disposition of fluticasone furoate, an enhanced-affinity glucocorticoid, in humans. | Hughes SC et al. | — | 2008 | → |
| Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia. | Pan XD et al. | — | 2008 | → |
| NF-kappaB and the intestine: friend or foe? | Karrasch T et al. | — | 2008 | → |
| NF-kappaB-inhibiting naphthopyrones from the Fijian echinoderm Comanthus parvicirrus. | Folmer F et al. | — | 2008 | → |
| NF-kappaB signaling, liver disease and hepatoprotective agents. | Sun B et al. | — | 2008 | → |
| NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: implications for Huntington's disease. | Napolitano M et al. | — | 2008 | → |
| Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. | Song LL et al. | — | 2008 | → |
| Novel iminobenzoxathiolone compound inhibits nuclear factor-kappaB activation targeting inhibitory kappaB kinase beta and down-regulating interleukin-1beta expression in lipopolysaccharide-activated macrophages. | Kim MH et al. | — | 2008 | → |
| Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis. | Lee RW et al. | — | 2008 | → |
| Nuclear factor-kappaB: fine-tuning a central integrator of diverse biologic stimuli. | Krakauer T | — | 2008 | → |
| Opposing functions of IKKbeta during acute and chronic intestinal inflammation. | Eckmann L et al. | — | 2008 | → |
| Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis. | Brune V et al. | — | 2008 | → |
| Protein damage by reactive electrophiles: targets and consequences. | Liebler DC | — | 2008 | → |
| Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells. | Kim SW et al. | — | 2008 | → |
| Regulation of programmed cell death by NF-kappaB and its role in tumorigenesis and therapy. | Fan Y et al. | — | 2008 | → |
| Regulation of the sumoylation system in gene expression. | Liu B et al. | — | 2008 | → |
| Resveratrol prevents fibrosis, NF-kappaB activation and TGF-beta increases induced by chronic CCl4 treatment in rats. | Chávez E et al. | — | 2008 | → |
| Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss. | Abu-Amer Y et al. | — | 2008 | → |
| Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice. | Cho SJ et al. | — | 2008 | → |
| Structural analogs of tylophora alkaloids may not be functional analogs. | Gao W et al. | — | 2008 | → |
| Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. | Sarnico I et al. | — | 2008 | → |
| Targeting the UPS as therapy in multiple myeloma. | Chauhan D et al. | — | 2008 | → |
| The aryl hydrocarbon receptor complex and the control of gene expression. | Beischlag TV et al. | — | 2008 | → |
| The IKK-NF-kappaB pathway: a source for novel molecular drug targets in pain therapy? | Niederberger E et al. | — | 2008 | → |
| The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells. | Dhawan P et al. | — | 2008 | → |
| The role of NF-kappaB in lymphoid malignancies. | Packham G | — | 2008 | → |
| Treatment of Hodgkin lymphoma: the past, present, and future. | Evens AM et al. | — | 2008 | → |
| Tumor necrosis factor and cancer, buddies or foes? | Wang X et al. | — | 2008 | → |
| Understanding NF-kappaB signaling via mathematical modeling. | Cheong R et al. | — | 2008 | → |
| Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer. | Chiang SL et al. | — | 2008 | → |
| A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor. | Davis RE et al. | — | 2007 | → |
| Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity. | Mazur I et al. | — | 2007 | → |
| A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. | Ju W et al. | — | 2007 | → |
| Adiponectin gene expression and adipocyte NF-kappaB transcriptional activity in elderly overweight and obese women: inter-relationships with fat distribution, hs-CRP, leptin and insulin resistance. | Zamboni M et al. | — | 2007 | → |
| A fourth IkappaB protein within the NF-kappaB signaling module. | Basak S et al. | — | 2007 | → |
| Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis. | Hsu YC et al. | — | 2007 | → |
| Anti-inflammatory effects of hydroxycinnamic acid derivatives. | Nagasaka R et al. | — | 2007 | → |
| A role for IkappaB kinase 2 in bipolar spindle assembly. | Irelan JT et al. | — | 2007 | → |
| Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kappaB activation and cytokine production. | Klemm S et al. | — | 2007 | → |
| Bortezomib inhibits human osteoclastogenesis. | von Metzler I et al. | — | 2007 | → |
| Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. | Berchtold CM et al. | — | 2007 | → |
| Constitutive and inducible nuclear factor-kappaB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines. | Baby J et al. | — | 2007 | → |
| Corticosteroids and beta2 agonists differentially regulate rhinovirus-induced interleukin-6 via distinct Cis-acting elements. | Edwards MR et al. | — | 2007 | → |
| Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability. | Esfandiarei M et al. | — | 2007 | → |
| Cytotoxicity of NF-kappaB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines. | Berger N et al. | — | 2007 | → |
| DnIKK2-transfected dendritic cells induce a novel population of inducible nitric oxide synthase-expressing CD4+CD25- cells with tolerogenic properties. | Aiello S et al. | — | 2007 | → |
| Down-regulation of iNOS and TNF-alpha expression by kaempferol via NF-kappaB inactivation in aged rat gingival tissues. | Kim HK et al. | — | 2007 | → |
| Drugs modulating the biological effects of peroxynitrite and related nitrogen species. | Olmos A et al. | — | 2007 | → |
| Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib. | An J et al. | — | 2007 | → |
| Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis. | Stathopoulos GT et al. | — | 2007 | → |
| Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment for rheumatoid arthritis. | Caggiano TJ et al. | — | 2007 | → |
| Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells. | Fazal F et al. | — | 2007 | → |
| Expression of a cyclo-oxygenase-2 transgene in murine liver causes hepatitis. | Yu J et al. | — | 2007 | → |
| Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro. | Geisler F et al. | — | 2007 | → |
| High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. | Weichert W et al. | — | 2007 | → |
| I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. | Greve B et al. | — | 2007 | → |
| IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms. | Otkjaer K et al. | — | 2007 | → |
| Individualized target therapy of malignant lymphomas: an outlook. | Anagnostopoulos I | — | 2007 | → |
| Inflammation and cancer: breast cancer as a prototype. | Mantovani A et al. | — | 2007 | → |
| Inflammation and lung carcinogenesis: applying findings in prevention and treatment. | Peebles KA et al. | — | 2007 | → |
| Influence of the fungal NF-kappaB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. | Erkel G et al. | — | 2007 | → |
| Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia. | Carvalho G et al. | — | 2007 | → |
| Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. | Yamini B et al. | — | 2007 | → |
| Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. | Yang Y et al. | — | 2007 | → |
| Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. | Mathew B et al. | — | 2007 | → |
| Integrating cell-signalling pathways with NF-kappaB and IKK function. | Perkins ND | — | 2007 | → |
| Involvement of protein kinase C in melatonin's oncostatic effect in C6 glioma cells. | Martín V et al. | — | 2007 | → |
| Liver regeneration. | Michalopoulos GK | — | 2007 | → |
| Loss of NF-kappaB activation in Kupffer cell-depleted mice impairs liver regeneration after partial hepatectomy. | Abshagen K et al. | — | 2007 | → |
| Magnetocapture of abalone transcription factor NF-kappaB: a new strategy for isolation and detection of NF-kappaB both in vitro and in vivo. | Jiang Y et al. | — | 2007 | → |
| Many faces of NF-kappaB signaling induced by genotoxic stress. | Wu ZH et al. | — | 2007 | → |
| Mitogen-activated protein kinases, inhibitory-kappaB kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity. | Bashan N et al. | — | 2007 | → |
| Molecular mechanisms in chronic obstructive pulmonary disease: potential targets for therapy. | de Boer WI et al. | — | 2007 | → |
| Mullerian-inhibiting substance induces Gro-beta expression in breast cancer cells through a nuclear factor-kappaB-dependent and Smad1-dependent mechanism. | Gupta V et al. | — | 2007 | → |
| Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model. | Jüttler E et al. | — | 2007 | → |
| New molecular targets for the treatment of neutrophilic diseases. | Barnes PJ | — | 2007 | → |
| NF-kappa B as a target for cancer therapy. | Melisi D et al. | — | 2007 | → |
| NF-kappa B as a therapeutic target in neurodegenerative diseases. | Camandola S et al. | — | 2007 | → |
| NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. | Fabre C et al. | — | 2007 | → |
| NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. | Greten FR et al. | — | 2007 | → |
| Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. | Tas SW et al. | — | 2007 | → |
| Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. | Du Z et al. | — | 2007 | → |
| Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis. | De Vry CG et al. | — | 2007 | → |
| Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway. | Yasui H et al. | — | 2007 | → |
| Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase. | Lavon I et al. | — | 2007 | → |
| Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. | Luo JL et al. | — | 2007 | → |
| Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis. | Elsharkawy AM et al. | — | 2007 | → |
| Nuclear factor-kappaB in development, prevention, and therapy of cancer. | Van Waes C | — | 2007 | → |
| Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis. | González-Ramos R et al. | — | 2007 | → |
| Nuclear factor-kappab (NF-kappaB): an unsuspected major culprit in the pathogenesis of endometriosis that is still at large? | Guo SW | — | 2007 | → |
| Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. | Algül H et al. | — | 2007 | → |
| Parthenolide inhibits tubulin carboxypeptidase activity. | Fonrose X et al. | — | 2007 | → |
| Pharmacological and histopathological characterization of a hyperalgesia model induced by freeze lesion. | Schmidtko A et al. | — | 2007 | → |
| Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease. | Salter M et al. | — | 2007 | → |
| Polyphenols in the treatment of inflammatory bowel disease and acute pancreatitis. | Shapiro H et al. | — | 2007 | → |
| Pre-B-cell colony-enhancing factor (PBEF/Visfatin) gene expression is modulated by NF-kappaB and AP-1 in human amniotic epithelial cells. | Kendal CE et al. | — | 2007 | → |
| Protein kinase R, IkappaB kinase-beta and NF-kappaB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells. | Edwards MR et al. | — | 2007 | → |
| PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta). | Shrestha S et al. | — | 2007 | → |
| Regulation of late B cell differentiation by intrinsic IKKalpha-dependent signals. | Mills DM et al. | — | 2007 | → |
| RelA is required for IL-1beta stimulation of Matrix Metalloproteinase-1 expression in chondrocytes. | Raymond L et al. | — | 2007 | → |
| Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors. | Newton R et al. | — | 2007 | → |
| Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity. | Kaileh M et al. | — | 2007 | → |
| SDX-308 and SDX-101, non-steroidal anti-inflammatory drugs, as therapeutic candidates for treating hematologic malignancies including myeloma. | Lentzsch S et al. | — | 2007 | → |
| Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways. | Wang X et al. | — | 2007 | → |
| Signaling mechanisms involved in disuse muscle atrophy. | Zhang P et al. | — | 2007 | → |
| Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you? | Vincenti MP et al. | — | 2007 | → |
| Suppression by Curcuma comosa Roxb. of pro-inflammatory cytokine secretion in phorbol-12-myristate-13-acetate stimulated human mononuclear cells. | Sodsai A et al. | — | 2007 | → |
| Survival and apoptotic pathways initiated by TNF-alpha: modeling and predictions. | Rangamani P et al. | — | 2007 | → |
| Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors. | Beaulieu F et al. | — | 2007 | → |
| Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors. | Belema M et al. | — | 2007 | → |
| Synthesis and structure activity relationship studies of benzothieno[3,2-b]furan derivatives as a novel class of IKKbeta inhibitors. | Sugiyama H et al. | — | 2007 | → |
| Systemic targeting inhibitor of kappaB kinase inhibits melanoma tumor growth. | Yang J et al. | — | 2007 | → |
| Targeted therapies for non-Hodgkin lymphoma: rationally designed combinations. | Martin P et al. | — | 2007 | → |
| Targeting apoptosis in solid tumors: the role of bortezomib from preclinical to clinical evidence. | Russo A et al. | — | 2007 | → |
| Targeting signal transduction in pancreatic cancer treatment. | Yeh JJ et al. | — | 2007 | → |
| The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages. | Vunta H et al. | — | 2007 | → |
| The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-alpha and IKK-beta kinases. | Christopher JA et al. | — | 2007 | → |
| The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. | Flaster H et al. | — | 2007 | → |
| The transcription factor nuclear factor-kappa B and cancer. | Escárcega RO et al. | — | 2007 | → |
| Toll-like receptors and innate immunity in gut homeostasis and pathology. | Michelsen KS et al. | — | 2007 | → |
| Tumor necrosis factor-alpha (TNF-alpha) regulates Toll-like receptor 2 (TLR2) expression in microglia. | Syed MM et al. | — | 2007 | → |
| Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. | Kaileh M et al. | — | 2007 | → |
| 17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway. | Wang X et al. | — | 2006 | → |
| AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin. | Girvan AC et al. | — | 2006 | → |
| Anti-HIV activity of stilbene-related heterocyclic compounds. | Bedoya LM et al. | — | 2006 | → |
| Can NF-kappaB be a target for novel and efficient anti-cancer agents? | Olivier S et al. | — | 2006 | → |
| Cell biology. The stress of finding NEMO. | Bartek J et al. | — | 2006 | → |
| Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells. | Coquelle A et al. | — | 2006 | → |
| Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation. | Campbell KJ et al. | — | 2006 | → |
| Corticosteroid effects on cell signalling. | Barnes PJ | — | 2006 | → |
| Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks. | Wagner S et al. | — | 2006 | → |
| Differential teratogenic response of TNFalpha+/+ and TNFalpha-/- mice to cyclophosphamide: the possible role of NF-kappaB. | Torchinsky A et al. | — | 2006 | → |
| Diverse pathways mediate chemotherapy-induced cell death in acute lymphoblastic leukemia cell lines. | Min DJ et al. | — | 2006 | → |
| Drug insight: Small-molecule inhibitors of protein kinases in the treatment of thyroid cancer. | Santoro M et al. | — | 2006 | → |
| Endotoxin triggers nuclear factor-kappaB-dependent up-regulation of multiple proinflammatory genes in the diaphragm. | Demoule A et al. | — | 2006 | → |
| Eriocalyxin B inhibits nuclear factor-kappaB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner. | Leung CH et al. | — | 2006 | → |
| Evolution of the thienopyridine class of inhibitors of IkappaB kinase-beta: part I: hit-to-lead strategies. | Morwick T et al. | — | 2006 | → |
| Exploiting our knowledge of NF-kappaB signaling for the treatment of mammary cancer. | Haffner MC et al. | — | 2006 | → |
| Future of toxicology--mechanisms of toxicity and drug safety: where do we go from here? | Stevens JL | — | 2006 | → |
| Good cop, bad cop: the different faces of NF-kappaB. | Perkins ND et al. | — | 2006 | → |
| Helicobacter pylori induces IkappaB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells. | Hirata Y et al. | — | 2006 | → |
| Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. | Imre G et al. | — | 2006 | → |
| IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis. | Schopf L et al. | — | 2006 | → |
| Inflammatory signal transduction from the Fc epsilon RI to NF-kappa B. | Klemm S et al. | — | 2006 | → |
| Inhibition of human immunodeficiency virus type 1 replication in latently infected cells by a novel IkappaB kinase inhibitor. | Victoriano AF et al. | — | 2006 | → |
| Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis. | Clohisy JC et al. | — | 2006 | → |
| Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. | Lee JH et al. | — | 2006 | → |
| Inhibition of TNFalpha-induced activation of nuclear factor kappaB by kava (Piper methysticum) derivatives. | Folmer F et al. | — | 2006 | → |
| Inhibitors of NF-kappaB signaling: 785 and counting. | Gilmore TD et al. | — | 2006 | → |
| Insights into the behaviour of systems biology models from dynamic sensitivity and identifiability analysis: a case study of an NF-kappaB signalling pathway. | Yue H et al. | — | 2006 | → |
| Interleukin 6, a nuclear factor-kappaB target, predicts resistance to docetaxel in hormone-independent prostate cancer and nuclear factor-kappaB inhibition by PS-1145 enhances docetaxel antitumor activity. | Domingo-Domenech J et al. | — | 2006 | → |
| Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin. | Martín V et al. | — | 2006 | → |
| In vitro evaluation of effects of two Ghanaian plants relevant to wound healing. | Mensah AY et al. | — | 2006 | → |
| In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells. | Neri P et al. | — | 2006 | → |
| Is nuclear factor kappa-B the missing link between inflammation, cancer and alteration in hepatic drug metabolism in patients with cancer? | Assenat E et al. | — | 2006 | → |
| Is there a role for TNF-alpha in anti-neutrophil cytoplasmic antibody-associated vasculitis? Lessons from other chronic inflammatory diseases. | Feldmann M et al. | — | 2006 | → |
| Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics. | Vanden Berghe W et al. | — | 2006 | → |
| Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation. | Tas SW et al. | — | 2006 | → |
| Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells. | Chen F et al. | — | 2006 | → |
| Malignant pheochromocytoma: state of the field with future projections. | Ahlman H | — | 2006 | → |
| Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses. | Hiscott J et al. | — | 2006 | → |
| Mechanism of macrophage activation by (1,4)-alpha-D-glucan isolated from Tinospora cordifolia. | Nair PK et al. | — | 2006 | → |
| Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. | Bergstralh DT et al. | — | 2006 | → |
| Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. | Wu ZH et al. | — | 2006 | → |
| Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance. | Bubici C et al. | — | 2006 | → |
| New therapies for asthma. | Barnes PJ | — | 2006 | → |
| New treatment regimes for virus-induced exacerbations of asthma. | Edwards MR et al. | — | 2006 | → |
| NF-kappaB and cancer: mechanisms and targets. | Karin M | — | 2006 | → |
| NF-kappaB and cytokines. | Kulms D et al. | — | 2006 | → |
| NF-kappaB: a stress-regulated switch for cell survival. | Piva R et al. | — | 2006 | → |
| NF-kappaB signaling: pros and cons of altering NF-kappaB as a therapeutic approach. | Egan LJ et al. | — | 2006 | → |
| NF-kappaB signalling in cerebral ischaemia. | Schwaninger M et al. | — | 2006 | → |
| Nitric oxide donor-induced persistent inhibition of cell adhesion protein expression and NFkappaB activation in endothelial cells. | Waldow T et al. | — | 2006 | → |
| Novel signal transduction modulators for the treatment of airway diseases. | Barnes PJ | — | 2006 | → |
| Nuclear factor-kappaB dimer exchange promotes a p21(waf1/cip1) superinduction response in human T leukemic cells. | Chang PY et al. | — | 2006 | → |
| Nuclear factor-kappaB in cancer development and progression. | Karin M | — | 2006 | → |
| Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL. | Peng Y et al. | — | 2006 | → |
| Perinatal brain injury and regulation of transcription. | Chang YC et al. | — | 2006 | → |
| Phosphoinositide 3-kinase mediated signalling contributes to development of diabetes-induced abnormal vascular reactivity of rat carotid artery. | Yousif MH et al. | — | 2006 | → |
| Preadministration of high-dose salicylates, suppressors of NF-kappaB activation, may increase the chemosensitivity of many cancers: an example of proapoptotic signal modulation therapy. | McCarty MF et al. | — | 2006 | → |
| Pro-apoptotic role of NF-kappaB: implications for cancer therapy. | Radhakrishnan SK et al. | — | 2006 | → |
| Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5. | Tanaka K et al. | — | 2006 | → |
| Proteasome inhibition in multiple myeloma. | Kropff M et al. | — | 2006 | → |
| Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta. | Nagashima K et al. | — | 2006 | → |
| Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. | Whittle BJ et al. | — | 2006 | → |
| Regulating the regulator: NF-kappaB signaling in heart. | Hall G et al. | — | 2006 | → |
| Regulation of cytokine signaling pathways by PIAS proteins. | Shuai K | — | 2006 | → |
| Regulation of lung inflammation in the model of IgG immune-complex injury. | Gao H et al. | — | 2006 | → |
| Role for IKK2 in muscle: waste not, want not. | Karin M | — | 2006 | → |
| Role of tumor-associated macrophages in tumor progression and invasion. | Mantovani A et al. | — | 2006 | → |
| Rosmarinic acid as a downstream inhibitor of IKK-beta in TNF-alpha-induced upregulation of CCL11 and CCR3. | Lee J et al. | — | 2006 | → |
| Sensitization of TRAIL-resistant cells by inhibition of heat shock protein 90 with low-dose geldanamycin. | Ma Y et al. | — | 2006 | → |
| Signal transduction of inflammatory cytokines and tumor development. | Yoshimura A | — | 2006 | → |
| Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. | Mourkioti F et al. | — | 2006 | → |
| Targeting NF-kappaB in hematologic malignancies. | Braun T et al. | — | 2006 | → |
| Targeting signal transduction as a strategy to treat inflammatory diseases. | O'Neill LA | — | 2006 | → |
| TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells. | Kim Y et al. | — | 2006 | → |
| The biology and biochemistry of inflammatory signalosomes. Meeting on signaling networks in immunity and inflammation. | Rawlings DJ | — | 2006 | → |
| The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. | Papa S et al. | — | 2006 | → |
| The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex. | Douillette A et al. | — | 2006 | → |
| The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. | Pérez-Galán P et al. | — | 2006 | → |
| The quest for new therapies in patients with cirrhosis and sepsis. Time to move from the lab to the bedside. | Quioc JJ et al. | — | 2006 | → |
| The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis. | Peng Y et al. | — | 2006 | → |
| The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta. | Yore MM et al. | — | 2006 | → |
| The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care? | Brégégère F et al. | — | 2006 | → |
| The valosin-containing protein (VCP) is a target of Akt signaling required for cell survival. | Vandermoere F et al. | — | 2006 | → |
| Toll-like receptors: a new target in rheumatoid arthritis? | Drexler SK et al. | — | 2006 | → |
| Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling. | Widera D et al. | — | 2006 | → |
| Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle. | Catley MC et al. | — | 2006 | → |
| Vascular endothelial growth factor signalling in endothelial cell survival: a role for NFkappaB. | Grosjean J et al. | — | 2006 | → |
| 10t,12c-conjugated linoleic acid inhibits lipopolysaccharide-induced cyclooxygenase expression in vitro and in vivo. | Li G et al. | — | 2005 | → |
| 4-Phenylcoumarins as HIV transcription inhibitors. | Bedoya LM et al. | — | 2005 | → |
| Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. | Hassa PO et al. | — | 2005 | → |
| Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse. | Domingo-Domenech J et al. | — | 2005 | → |
| Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers. | Zhou Y et al. | — | 2005 | → |
| Adenovirus-mediated gene transfer of mutated IkappaB kinase and IkappaBalpha reveal NF-kappaB-dependent as well as NF-kappaB-independent pathways of HAS1 activation. | Stuhlmeier KM et al. | — | 2005 | → |
| Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. | Broide DH et al. | — | 2005 | → |
| A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells. | Chauhan D et al. | — | 2005 | → |
| Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappaB in oral keratinocytes. | Lin SC et al. | — | 2005 | → |
| A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity. | Ziegelbauer K et al. | — | 2005 | → |
| beta-Carboline alkaloid suppresses NF-kappaB transcriptional activity through inhibition of IKK signaling pathway. | Yoon JW et al. | — | 2005 | → |
| Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy. | Kasperczyk H et al. | — | 2005 | → |
| Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway. | Gómez-Muñoz A et al. | — | 2005 | → |
| Chronic treatment with agents that stabilize cytosolic IkappaB-alpha enhances survival and improves resting membrane potential in MDX muscle fibers subjected to chronic passive stretch. | Carlson CG et al. | — | 2005 | → |
| Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression. | Pattoli MA et al. | — | 2005 | → |
| Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells. | Shirley RB et al. | — | 2005 | → |
| Common patterns in type II restriction enzyme binding sites. | Nikolajewa S et al. | — | 2005 | → |
| Deficiency in Ikkbeta gene enhances arsenic-induced gadd45alpha expression. | Zhang Y et al. | — | 2005 | → |
| Dendritic cells genetically engineered with adenoviral vector encoding dnIKK2 induce the formation of potent CD4+ T-regulatory cells. | Tomasoni S et al. | — | 2005 | → |
| Elucidating mechanisms of drug-induced toxicity. | Liebler DC et al. | — | 2005 | → |
| Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction. | Wuerzberger-Davis SM et al. | — | 2005 | → |
| Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver. | Boden G et al. | — | 2005 | → |
| From cellular receptors to transduction-transcription pathways for cytokines: at which level should the inhibition be targeted in inflammation? | Dayer JM et al. | — | 2005 | → |
| Glycogen synthase kinase-3 mediates endothelial cell activation by tumor necrosis factor-alpha. | Eto M et al. | — | 2005 | → |
| IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. | Maeda S et al. | — | 2005 | → |
| IKK mediates ischemia-induced neuronal death. | Herrmann O et al. | — | 2005 | → |
| IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy. | Luo JL et al. | — | 2005 | → |
| Individualised cancer therapeutics: dream or reality? | Senzer N et al. | — | 2005 | → |
| Inflammation-associated cancer: NF-kappaB is the lynchpin. | Li Q et al. | — | 2005 | → |
| Inhibitor-kappaB kinase-beta regulates LPS-induced TNF-alpha production in cardiac myocytes through modulation of NF-kappaB p65 subunit phosphorylation. | Hall G et al. | — | 2005 | → |
| In the Crosshairs: NF-κB Targets the JNK Signaling Cascade. | Pham CG et al. | — | 2005 | → |
| Limiting inflammatory responses during activation of innate immunity. | Han J et al. | — | 2005 | → |
| LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia. | Qin H et al. | — | 2005 | → |
| Molecular recognition of 15-deoxy-delta(12,14)-prostaglandin J2 by nuclear factor-kappa B and other cellular proteins. | Pande V et al. | — | 2005 | → |
| Molecular requirements for epithelial-mesenchymal transition during tumor progression. | Huber MA et al. | — | 2005 | → |
| NF-kappaB: linking inflammation and immunity to cancer development and progression. | Karin M et al. | — | 2005 | → |
| NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation. | Hu WH et al. | — | 2005 | → |
| Nuclear factor-kappaB and liver carcinogenesis. | Arsura M et al. | — | 2005 | → |
| Nuclear factor kappa B signaling in macrophage function and atherogenesis. | Xanthoulea S et al. | — | 2005 | → |
| Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. | Kray AE et al. | — | 2005 | → |
| Proteasome inhibitors abrogate osteoclast differentiation and osteoclast function. | Zavrski I et al. | — | 2005 | → |
| Real-time imaging of ligand-induced IKK activation in intact cells and in living mice. | Gross S et al. | — | 2005 | → |
| Regulation of c-Jun phosphorylation by the I kappa B kinase-epsilon complex in fibroblast-like synoviocytes. | Sweeney SE et al. | — | 2005 | → |
| Regulation of gene-activation pathways by PIAS proteins in the immune system. | Shuai K et al. | — | 2005 | → |
| Relationship between constitutive nuclear factor-kappaB (NF-kappaB) and inhibitor kappaB-alpha (IkappaB-alpha) in an interferon-alpha-sensitive human Burkitt lymphoma cell line. | Rath PC | — | 2005 | → |
| RETRACTED: A magnetic nanoprobe technology for detecting molecular interactions in live cells. | Won J et al. | — | 2005 | → |
| Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kappaB signalling in intestinal epithelial cells. | Kim JS et al. | — | 2005 | → |
| Second-generation kinase inhibitors. | Klebl BM et al. | — | 2005 | → |
| Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation. | Carter RS et al. | — | 2005 | → |
| Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. | Tian Q et al. | — | 2005 | → |
| Stimulus specificity of gene expression programs determined by temporal control of IKK activity. | Werner SL et al. | — | 2005 | → |
| Targeting kinases in asthma. | Blease K | — | 2005 | → |
| Teratogen-induced apoptotic cell death: does the apoptotic machinery act as a protector of embryos exposed to teratogens? | Torchinsky A et al. | — | 2005 | → |
| The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-kappaB activation induced via interaction between Akt and IkappaB kinase-beta in breast cancer cells. | Vandermoere F et al. | — | 2005 | → |
| The NF-kappaB signalling pathway: a therapeutic target in lymphoid malignancies? | Stoffel A | — | 2005 | → |
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