Effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT).
- Authors
- UKATT Research Team
- Year
- 2005
- Journal
- BMJ (Clinical research ed.)
- PMID
- 16150764
- DOI
- 10.1136/bmj.331.7516.541
- PMCID
- PMC1200586
OBJECTIVE: To compare the effectiveness of social behaviour and network therapy, a new treatment for alcohol problems, with that of the proved motivational enhancement therapy. DESIGN: Pragmatic randomised trial. SETTING: Seven treatment sites around Birmingham, Cardiff, and Leeds. PARTICIPANTS: 742 clients with alcohol problems; 689 (93.0%) were interviewed at three months and 617 (83.2%) at 12 months. INTERVENTIONS: Social behaviour and network therapy and motivational enhancement therapy. MAIN OUTCOME MEASURES: Changes in alcohol consumption, alcohol dependence, and alcohol related problems over 12 months. RESULTS: Both groups reported substantial reductions in alcohol consumption, dependence, and problems, and better mental health related quality of life over 12 months. Between groups we found only one significant difference in outcome, probably due to chance: the social network group showed significantly better physical health at three months. Non-significant differences at 12 months in the motivational group relative to the social network group included: the number of drinks consumed per drinking day had decreased by an extra 1.1 (95% confidence interval -1.0 to 3.2); scores on the Leeds dependence questionnaire had improved by an extra 0.6 (-0.7 to 2.0); scores on the alcohol problems questionnaire had improved by an extra 0.5 (-0.4 to 1.4); but the number of days abstinent from drinking had increased by 1.2% less (-4.5% to 6.9%). CONCLUSION: The novel social behaviour and network therapy for alcohol problems did not differ significantly in effectiveness from the proved motivational enhancement therapy.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Prediction of Relapse Using Digital Technology in People in Recovery From Substance Use Disorders: Early Economic Evaluation With a Case Study of the Subreal App. | Bouttell J et al. | β | 2026 | β |
| Single-session behavioral activation for alcohol use disorder: a randomized controlled pilot trial. | Frohlich F et al. | β | 2026 | β |
| Acknowledging the crucial role of Max Glatt in the development of the Jellinek curve and the enduring relevance of his model of recovery from problem drinking. | McInerney K et al. | β | 2025 | β |
| A cost-effectiveness analysis of two psychological treatments for controlled drinking in individuals alcohol use disorder. | Flores S et al. | β | 2025 | β |
| Effects of optimism and stage of change on alcohol use and problems among sexual minority men with HIV participating in a brief motivational interviewing intervention. | Berey BL et al. | β | 2025 | β |
| Evaluating telehealth and text-based interventions for at-risk drinkers: A pilot study of feasibility and efficacy. | Morgenstern J et al. | β | 2025 | β |
| Quality of life assessment instruments used in clinical trials for alcohol use disorder: A systematic review. | Tryggedsson JSJ et al. | β | 2025 | β |
| Behavioural self-control training versus motivational enhancement therapy for individuals with alcohol use disorder with a goal of controlled drinking: A randomized controlled trial. | Hammarberg SI et al. | β | 2024 | β |
| Designing and testing treatments for alcohol use disorder. | Witkiewitz K et al. | β | 2024 | β |
| Mental Imagery to Reduce Alcohol-related harm in patients with alcohol use disorder and alcohol-related liver damaGE: the MIRAGE randomised pilot trial results. | Dhanda A et al. | β | 2024 | β |
| Adjunctive Medication Management and Contingency Management to enhance adherence to acamprosate for alcohol dependence: the ADAM trial RCT. | Donoghue K et al. | β | 2023 | β |
| A qualitative interview study of patient experiences of receiving motivational enhancement therapy in a Swedish addiction specialist treatment setting. | Ingesson Hammarberg S et al. | β | 2023 | β |
| Common strategies in empirically supported psychological interventions for alcohol use disorders: A meta-review. | Nadkarni A et al. | β | 2023 | β |
| Motivational interviewing for substance use reduction. | Schwenker R et al. | β | 2023 | β |
| The effectiveness of social network interventions for psychiatric patients: A systematic review and meta-analysis. | Swinkels LTA et al. | β | 2023 | β |
| The evolution of motivational interviewing. | Miller WR | β | 2023 | β |
| Collective Motivational Interviewing for Individuals with Drug Use Problems: A Pre-Post-Follow-Up, Uncontrolled Pilot Study. | Tse N et al. | β | 2022 | β |
| COVID-19 Lockdown and Consumption Patterns among Substance Use Disorder Outpatients: A Multicentre Study. | Grau-LΓ³pez L et al. | β | 2022 | β |
| Mental Imagery to Reduce Alcohol-related harm in patients with alcohol dependence and alcohol-related liver damaGE: the MIRAGE pilot trial protocol. | Dhanda AD et al. | β | 2022 | β |
| Personality traits and alcohol consumption: Secondary analysis of the Self-Match Study. | Hell ME et al. | β | 2022 | β |
| Serial mediation analysis of treatment-specific processes in two contrasting alcohol treatments. | Gaume J et al. | β | 2022 | β |
| Understanding How and Why Alcohol Interventions Prevent and Reduce Problematic Alcohol Consumption among Older Adults: A Systematic Review. | Boumans J et al. | β | 2022 | β |
| An application of moderated nonlinear factor analysis to develop a commensurate measure of alcohol problems across four alcohol treatment studies. | Richards DK et al. | β | 2021 | β |
| A Preliminary Evaluation of Mobile Phone Apps to Curb Alcohol Consumption. | Mubin O et al. | β | 2021 | β |
| First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder. | Sessa B et al. | β | 2021 | β |
| SF-6D utility scores for alcohol use disorder status and alcohol consumption risk levels in the US population. | Barbosa C et al. | β | 2021 | β |
| The impact of free choice in alcohol treatment. Primary outcomes of the self-match study. | Hell ME et al. | β | 2021 | β |
| Brief motivational therapy versus enhanced usual care for alcohol use disorders in primary care in Chile: study protocol for an exploratory randomized trial. | Barticevic NA et al. | β | 2020 | β |
| Craving mediates the effect of impulsivity on lapse-risk during alcohol use disorder treatment. | Coates JM et al. | β | 2020 | β |
| Managing alcohol use in primary care. | McCambridge J et al. | β | 2020 | β |
| Treatment interventions to maintain abstinence from alcohol in primary care: systematic review and network meta-analysis. | Cheng HY et al. | β | 2020 | β |
| World Health Organization risk drinking level reductions are associated with improved functioning and are sustained among patients with mild, moderate and severe alcohol dependence in clinical trials in the United States and United Kingdom. | Witkiewitz K et al. | β | 2020 | β |
| Feasibility, acceptability and cost-effectiveness of a brief, lay counsellor-delivered psychological treatment for men with alcohol dependence in primary care: an exploratory randomized controlled trial. | Nadkarni A et al. | β | 2019 | β |
| The Impact of Therapists' Responses to Resistance to Change: A Sequential Analysis of Therapist Client Interactions in Motivational Interviewing. | Drage L et al. | β | 2019 | β |
| Alcohol and Opioid Use, Co-Use, and Chronic Pain in the Context of the Opioid Epidemic: A Critical Review. | Witkiewitz K et al. | β | 2018 | β |
| Alcohol-Related Nurse Care Management in Primary Care: A Randomized Clinical Trial. | Bradley KA et al. | β | 2018 | β |
| A pilot feasibility randomised controlled trial of an adjunct brief social network intervention in opiate substitution treatment services. | Day E et al. | β | 2018 | β |
| A Randomized Trial of Personalized Cognitive-Behavior Therapy for Alcohol Use Disorder in a Public Health Clinic. | Coates JM et al. | β | 2018 | β |
| Duration of therapy - Does it matter?: A systematic review and meta-regression of the duration of psychosocial treatments for alcohol use disorder. | Kramer Schmidt L et al. | β | 2018 | β |
| Is treatment outcome improved if patients match themselves to treatment options? Study protocol for a randomized controlled trial. | Hell ME et al. | β | 2018 | β |
| Nurse-led clinic for patients with liver cirrhosis-effects on health-related quality of life: study protocol of a pragmatic multicentre randomised controlled trial. | Hjorth M et al. | β | 2018 | β |
| Therapeutic alliance predicts mood but not alcohol outcome in a comorbid treatment setting. | Richardson D et al. | β | 2018 | β |
| Therapist-Client Interactions in Motivational Interviewing: The Effect of Therapists' Utterances on Client Change Talk. | Brown M et al. | β | 2018 | β |
| A feasibility randomised controlled trial of extended brief intervention for alcohol misuse in adults with mild to moderate intellectual disabilities living in the community; The EBI-LD study. | Kouimtsidis C et al. | β | 2017 | β |
| Assertive Community Treatment For People With Alcohol Dependence: A Pilot Randomized Controlled Trial. | Drummond C et al. | β | 2017 | β |
| Effectiveness and Cost-effectiveness of Opportunistic Screening and Stepped-care Interventions for Older Alcohol Users in Primary Care. | Coulton S et al. | β | 2017 | β |
| How Much Is Too Much? Patterns of Drinking During Alcohol Treatment and Associations With Post-Treatment Outcomes Across Three Alcohol Clinical Trials. | Witkiewitz K et al. | β | 2017 | β |
| Orbitofrontal cortex connectivity as a mechanism of adolescent behavior change. | Feldstein Ewing SW et al. | β | 2017 | β |
| Predicting drinking outcomes: Evidence from the United Kingdom Alcohol Treatment Trial (UKATT). | Dale V et al. | β | 2017 | β |
| Psychosocial interventions for addiction-affected families in Low and Middle Income Countries: A systematic review. | Rane A et al. | β | 2017 | β |
| Substance use outcomes following treatment: Findings from the Australian Patient Pathways Study. | Manning V et al. | β | 2017 | β |
| Ambivalence: Prerequisite for success in motivational interviewing with adolescents? | Feldstein Ewing SW et al. | β | 2016 | β |
| Client experiences of motivational interviewing: An interpersonal process recall study. | Jones SA et al. | β | 2016 | β |
| Craving Mediates Stress in Predicting Lapse During Alcohol Dependence Treatment. | Law B et al. | β | 2016 | β |
| Patient-centered care interventions for the management of alcohol use disorders: a systematic review of randomized controlled trials. | Barrio P et al. | β | 2016 | β |
| Preference weights for the spectrum of alcohol use in the U.S. Population. | Chavez LJ et al. | β | 2016 | β |
| Qualitative and quantitative feedback following workshop training in evidence-based practices: A dissemination study. | Houck JM et al. | β | 2016 | β |
| Reduced Social Network Drinking is Associated with Improved Response Inhibition in Women During Early Recovery from Alcohol Use Disorders: A Pilot Study. | McCutcheon VV et al. | β | 2016 | β |
| Remission from substance use disorders: A systematic review and meta-analysis. | Fleury MJ et al. | β | 2016 | β |
| Reproducibility and differential item functioning of the alcohol dependence syndrome construct across four alcohol treatment studies: An integrative data analysis. | Witkiewitz K et al. | β | 2016 | β |
| STREAM: Elucidating How Alcohol Use Disorders are Managed in UK General Practice Today. | Coste F et al. | β | 2016 | β |
| ADAPTA: A pilot randomised controlled trial of an alcohol-focused intervention versus a healthy living intervention for problem drinkers identified in a general hospital setting. | Watson JM et al. | β | 2015 | β |
| Ahead of its time: 40 years after the advice versus treatment family study. | Orford J | β | 2015 | β |
| A randomised controlled feasibility trial of family and social network intervention for young people who misuse alcohol and drugs: study protocol (Y-SBNT). | Watson J et al. | β | 2015 | β |
| Association between physical pain and alcohol treatment outcomes: The mediating role of negative affect. | Witkiewitz K et al. | β | 2015 | β |
| DIgital Alcohol Management ON Demand (DIAMOND) feasibility randomised controlled trial of a web-based intervention to reduce alcohol consumption in people with hazardous and harmful use versus a face-to-face intervention: protocol. | Hamilton FL et al. | β | 2015 | β |
| No More Waiting Lists. | Miller WR | β | 2015 | β |
| Pain as a predictor of heavy drinking and any drinking lapses in the COMBINE study and the UK Alcohol Treatment Trial. | Witkiewitz K et al. | β | 2015 | β |
| Posttreatment motivation and alcohol treatment outcome 9 months later: findings from structural equation modeling. | Cook S et al. | β | 2015 | β |
| Recommendations for the Design and Analysis of Treatment Trials for Alcohol Use Disorders. | Witkiewitz K et al. | β | 2015 | β |
| The forest and the trees: relational and specific factors in addiction treatment. | Miller WR et al. | β | 2015 | β |
| The role of the working alliance in treatment for alcohol problems. | Cook S et al. | β | 2015 | β |
| Alcohol screening and brief interventions for offenders in the probation setting (SIPS Trial): a pragmatic multicentre cluster randomized controlled trial. | Newbury-Birch D et al. | β | 2014 | β |
| Anorexia nervosa and social contagion: clinical implications. | Allison S et al. | β | 2014 | β |
| Current treatment options for alcohol-related liver disease. | Hazeldine S et al. | β | 2014 | β |
| Do brief alcohol motivational interventions work like we think they do? | Bertholet N et al. | β | 2014 | β |
| Is there more to psychosocial treatments in addiction than brief interventions? | Kelleher E | β | 2014 | β |
| Quality of life among hazardous and harmful drinkers: EQ-5D over a 1-year follow-up period. | Essex HN et al. | β | 2014 | β |
| Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. | McCutcheon VV et al. | β | 2014 | β |
| Talking about friends, drugs, and change: meanings of friendship in substance abusers' change talk. | Sarpavaara H | β | 2014 | β |
| The effectiveness and ineffectiveness of complex behavioral interventions: impact of treatment fidelity. | Miller WR et al. | β | 2014 | β |
| The efficacy-effectiveness distinction in trials of alcohol brief intervention. | Heather N | β | 2014 | β |
| Is depression contagious? The importance of social networks and the implications of contagion theory. | Bastiampillai T et al. | β | 2013 | β |
| Pilot study of a social network intervention for heroin users in opiate substitution treatment: study protocol for a randomized controlled trial. | Day E et al. | β | 2013 | β |
| Post-treatment stage of change predicts 12-month outcome of treatment for alcohol problems. | Heather N et al. | β | 2013 | β |
| Reduced-risk drinking as a viable treatment goal in problematic alcohol use and alcohol dependence. | van Amsterdam J et al. | β | 2013 | β |
| Treatment outcome and its predictors among Asian problem drinkers. | Manning V et al. | β | 2013 | β |
| Contingency management in substance abuse treatment: a structured review of the evidence for its transportability. | Hartzler B et al. | β | 2012 | β |
| Review of outcome research on marital and family therapy in treatment for alcoholism. | O'Farrell TJ et al. | β | 2012 | β |
| The effectiveness of psychosocial modalities in the treatment of alcohol problems in adults: a review of the evidence. | Martin GW et al. | β | 2012 | β |
| The impact of significant others in motivational enhancement therapy: findings from project MATCH. | Manuel JK et al. | β | 2012 | β |
| The role of demographic characteristics and readiness to change in 12-month outcome from two distinct brief interventions for impaired drivers. | Brown TG et al. | β | 2012 | β |
| A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). | Owens L et al. | β | 2011 | β |
| How psychosocial alcohol interventions work: a preliminary look at what FMRI can tell us. | Feldstein Ewing SW et al. | β | 2011 | β |
| Motivational interviewing for substance abuse. | Smedslund G et al. | β | 2011 | β |
| Pre-treatment expectations in clients: impact on retention and effectiveness in outpatient substance abuse treatment. | Kuusisto K et al. | β | 2011 | β |
| Proposed model of the neurobiological mechanisms underlying psychosocial alcohol interventions: the example of motivational interviewing. | Feldstein Ewing SW et al. | β | 2011 | β |
| Commentary on Witkiewitz et al. (2010): evidence for matching--at last. | Tober G | β | 2010 | β |
| Determinants of early reductions in drinking in older at-risk drinkers participating in the intervention arm of a trial to reduce at-risk drinking in primary care. | Lin JC et al. | β | 2010 | β |
| Individualised treatment in alcohol-dependent patients. | Mann K et al. | β | 2010 | β |
| New methodological directions for psychological intervention research among substance users. | Baker AL | β | 2010 | β |
| Predictors of motivation for abstinence at the end of outpatient substance abuse treatment. | Laudet AB et al. | β | 2010 | β |
| The 10 most important things known about addiction. | Sellman D | β | 2010 | β |
| Changing network support for drinking: network support project 2-year follow-up. | Litt MD et al. | β | 2009 | β |
| Packages of care for alcohol use disorders in low- and middle-income countries. | Benegal V et al. | β | 2009 | β |
| Progressive stage transition does mean getting better: a further test of the Transtheoretical Model in recovery from alcohol problems. | Heather N et al. | β | 2009 | β |
| Toward a theory of motivational interviewing. | Miller WR et al. | β | 2009 | β |
| To what factors do clients attribute change? Content analysis of follow-up interviews with clients of the UK Alcohol Treatment Trial. | Orford J et al. | β | 2009 | β |
| What was useful about that session? Clients' and therapists' comments after sessions in the UK Alcohol Treatment Trial (UKATT). | Orford J et al. | β | 2009 | β |
| Asking the right questions in the right way: the need for a shift in research on psychological treatments for addiction. | Orford J | β | 2008 | β |
| Development of a psychologically enhanced interactive online intervention for hazardous drinking. | Linke S et al. | β | 2008 | β |
| Diagnosis and management of alcohol use disorders. | Parker AJ et al. | β | 2008 | β |
| Joining the queue of dissenters. | Orford J | β | 2008 | β |
| Nursing interventions for preventing alcohol-related harm. | Littlejohn C et al. | β | 2008 | β |
| Specialised alcohol treatment services are a luxury the NHS cannot afford. | Luty J et al. | β | 2008 | β |
| The effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care (AESOPS) - a randomised control trial protocol. | Coulton S et al. | β | 2008 | β |
| UK Alcohol Treatment Trial: client-treatment matching effects. | UKATT Research Team | β | 2008 | β |
| Validation of a scale for rating the delivery of psycho-social treatments for alcohol dependence and misuse: the UKATT Process Rating Scale (PRS). | Tober G et al. | β | 2008 | β |
| A broader view of change in drinking behavior. | Willenbring ML | β | 2007 | β |
| An exploration of research into substance misuse and psychiatric disorder in the UK: what can we learn from history? | Crome IB | β | 2007 | β |
| A vision of the next generation of behavioral therapies research in the addictions. | Carroll KM et al. | β | 2007 | β |
| Conversation with Nick Heather. | Heather N | β | 2007 | β |
| Mechanisms, determinants and processes of change in the modification of drinking behavior. | DiClemente CC | β | 2007 | β |
| Rethinking the paradigms that inform behavioral treatment research for substance use disorders. | Morgenstern J et al. | β | 2007 | β |
| Safety in numbers? Tackling domestic abuse in couples and network therapies. | Galvani SA | β | 2007 | β |
| Site matters: multisite randomized trial of motivational enhancement therapy in community drug abuse clinics. | Ball SA et al. | β | 2007 | β |
| Theory-based active ingredients of effective treatments for substance use disorders. | Moos RH | β | 2007 | β |
| The psychological science of addiction. | Gifford E et al. | β | 2007 | β |
| Training and fidelity monitoring of behavioral interventions in multi-site addictions research. | Baer JS et al. | β | 2007 | β |
| Course of recovery from alcoholism. | Venner KL et al. | β | 2006 | β |
| Family interventions for drug and alcohol misuse: is there a best practice? | Copello AG et al. | β | 2006 | β |
| Still a difficult business? Negotiating alcohol-related problems in general practice consultations. | Rapley T et al. | β | 2006 | β |
| The clients' perspective on change during treatment for an alcohol problem: qualitative analysis of follow-up interviews in the UK Alcohol Treatment Trial. | Orford J et al. | β | 2006 | β |
| British drinking: a suitable case for treatment? | Hall W | β | 2005 | β |
| Cost effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT). | UKATT Research Team | β | 2005 | β |