A histone deacetylase regulates addiction.
paper
Cited
Public
Unavailable
- Authors
- Impey, Soren
- Year
- 2007
- Journal
- Neuron
- PMID
- 17988625
- DOI
- 10.1016/j.neuron.2007.10.029
Epigenetic modification of chromatin has been proposed to translate environmental stimuli into persistent "cellular memories." Recent studies suggest that epigenetic pathways regulate long-term behavioral adaptation in the nervous system. In this issue of Neuron, Renthal et al. utilize genetic manipulations of HDAC5 to provide strong evidence for a role for histone acetylation in the behavioral response to cocaine.
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In this knowledge base
| Title | Year | PMID |
|---|---|---|
| The genetic epidemiology of substance use disorder: A review. | 2017 | 28938182 |
| Epigenetics, microRNA, and addiction. | 2014 | 25364284 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| The genetic epidemiology of substance use disorder: A review. | Prom-Wormley EC et al. | — | 2017 | → |
| "Feature Detection" vs. "Predictive Coding" Models of Plant Behavior. | Calvo P et al. | — | 2016 | → |
| Epigenetics, microRNA, and addiction. | Kenny PJ | — | 2014 | → |
| Methamphetamine induces dynamic changes of histone deacetylases in different phases of behavioral sensitization. | Li H et al. | — | 2014 | → |
| Effect of the histone deacetylase inhibitors on behavioural sensitization to a single morphine exposure in mice. | Jing L et al. | — | 2011 | → |
| Epigenetic mechanisms in Alzheimer's disease. | Mastroeni D et al. | — | 2011 | → |
| Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. | Koga M et al. | — | 2009 | → |