Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.
paper
Cited
Public
Unavailable
- Authors
- Wang, Gaofeng; van der Walt, Joelle M; Mayhew, Gregory; Li, Yi-Ju; ZΓΌchner, Stephan; Scott, William K; Martin, Eden R; Vance, Jeffery M
- Year
- 2008
- Journal
- American journal of human genetics
- PMID
- 18252210
- DOI
- 10.1016/j.ajhg.2007.09.021
- PMCID
- PMC2427225
Parkinson disease (PD) is a common neurodegenerative disorder caused by environmental and genetic factors. We have previously shown linkage of PD to chromosome 8p. Subsequently, fibroblast growth factor 20 (FGF20) at 8p21.3-22 was identified as a risk factor in several association studies. To identify the risk-conferring polymorphism in FGF20, we performed genetic and functional analysis of single-nucleotide polymorphisms within the gene. In a sample of 729 nuclear families with 1089 affected and 1165 unaffected individuals, the strongest evidence of association came from rs12720208 in the 3' untranslated region of FGF20. We show in several functional assays that the risk allele for rs12720208 disrupts a binding site for microRNA-433, increasing translation of FGF20 in vitro and in vivo. In a cell-based system and in PD brains, this increase in translation of FGF20 is correlated with increased alpha-synuclein expression, which has previously been shown to cause PD through both overexpression and point mutations. We suggest a novel mechanism of action for PD risk in which the modulation of the susceptibility gene's translation by common variations interfere with the regulation mechanisms of microRNA. We propose this is likely to be a common mechanism of genetic modulation of individual susceptibility to complex disease.
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| miRNAs in neurodegenerative diseases: from target screening to precision therapy. | Liao D et al. | β | 2025 | β |
| Pathology and Therapeutic Significance of Fibroblast Growth Factors. | Edirisinghe O et al. | β | 2025 | β |
| RNA-Based Therapies for Neurodegenerative Diseases Targeting Pathogenic Proteins. | Rabbani SA et al. | β | 2025 | β |
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| The Role of miRNAs in Parkinson's Disease: A Systematic Review. | Chrysanthou M et al. | β | 2025 | β |
| Upregulation of miR-361-5p attenuates MPP<sup>+</sup>-induced neurotoxicity in dopaminergic SH-SY5Y cells as Parkinson's disease model. | Vaheb Hosseinabadi S et al. | β | 2025 | β |
| Diagnostic and mechanistic roles of MicroRNAs in neurodevelopmental & neurodegenerative disorders. | Khoodoruth MAS et al. | β | 2024 | β |
| Small Differences and Big Changes: The Many Variables of MicroRNA Expression and Function in the Brain. | Parkins EV et al. | β | 2024 | β |
| Small RNA Profiles of Brain Tissue-Derived Extracellular Vesicles in Alzheimer's Disease. | Huang Y et al. | β | 2024 | β |
| Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study. | Zhang R et al. | β | 2023 | β |
| miRNA in Parkinson's disease:Β From pathogenesis to theranostic approaches. | Elangovan A et al. | β | 2023 | β |
| Oxidative Stress and Aging as Risk Factors for Alzheimer's Disease and Parkinson's Disease: The Role of the Antioxidant Melatonin. | Tchekalarova J et al. | β | 2023 | β |
| PTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability. | Fevga C et al. | β | 2023 | β |
| Regulation of LncRNAs and microRNAs in neuronal development and disease. | Xuan C et al. | β | 2023 | β |
| The microRNAs (miRs) overexpressing mesenchymal stem cells (MSCs) therapy in neurological disorders; hope or hype. | Shelash Al-Hawary SI et al. | β | 2023 | β |
| The role of microRNAs in neurodegenerative diseases: a review. | Li S et al. | β | 2023 | β |
| Computational Detection of Pre-microRNAs. | SaΓ§ar Demirci MD | β | 2022 | β |
| Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration. | Prakash N | β | 2022 | β |
| Differentially Expressed miRNAs in Age-Related Neurodegenerative Diseases: A Meta-Analysis. | Noronha O et al. | β | 2022 | β |
| Emerging urinary alpha-synuclein and miRNA biomarkers in Parkinson's disease. | Giri B et al. | β | 2022 | β |
| MicroRNA machinery in Parkinson's disease: a platform for neurodegenerative diseases. | Saghazadeh A et al. | β | 2022 | β |
| miRNA and antisense oligonucleotide-based Ξ±-synuclein targeting as disease-modifying therapeutics in Parkinson's disease. | Suvarna V et al. | β | 2022 | β |
| Quantitative assessment of the effect of FGF20 rs1721100 and rs12720208 variant on the risk of sporadic Parkinson's disease: a meta-analysis. | Quan W et al. | β | 2022 | β |
| Role of MicroRNAs, Aptamers in Neuroinflammation and Neurodegenerative Disorders. | Khan I et al. | β | 2022 | β |
| Role of miRNAs in Neurodegeneration: From Disease Cause to Tools of Biomarker Discovery and Therapeutics. | Roy B et al. | β | 2022 | β |
| Uncovering the impact of noncoding variants in neurodegenerative brain diseases. | Frydas A et al. | β | 2022 | β |
| Chemical and Biological Molecules Involved in Differentiation, Maturation, and Survival of Dopaminergic Neurons in Health and Parkinson's Disease: Physiological Aspects and Clinical Implications. | Gaggi G et al. | β | 2021 | β |
| Exosomal miRNA as peripheral biomarkers in Parkinson's disease and progressive supranuclear palsy: A pilot study. | Manna I et al. | β | 2021 | β |
| Fibroblast Growth Factor 20 Gene Polymorphism in Parkinson's Disease in Asian Population: A Meta-Analysis. | Chiang HL et al. | β | 2021 | β |
| Parkinson's disease and microRNAs - Lessons from model organisms and human studies. | Evans B et al. | β | 2021 | β |
| Recent Evidence in Epigenomics and Proteomics Biomarkers for Early and Minimally Invasive Diagnosis of Alzheimer's and Parkinson's Diseases. | Mayo S et al. | β | 2021 | β |
| SNPs in miRNAs and Target Sequences: Role in Cancer and Diabetes. | Chhichholiya Y et al. | β | 2021 | β |
| Targeted sequencing of Parkinson's disease loci genes highlights SYT11, FGF20 and other associations. | Rudakou U et al. | β | 2021 | β |
| The Emerging Role of Long Non-Coding RNAs and MicroRNAs in Neurodegenerative Diseases: A Perspective of Machine Learning. | GarcΓa-Fonseca Γ et al. | β | 2021 | β |
| Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk. | Jacinta-Fernandes A et al. | β | 2020 | β |
| Clinical Application of Circulating MicroRNAs in Parkinson's Disease: The Challenges and Opportunities as Diagnostic Biomarker. | Ramaswamy P et al. | β | 2020 | β |
| Genetic Analysis of <i>RAB39B</i> in an Early-Onset Parkinson's Disease Cohort. | Gao Y et al. | β | 2020 | β |
| Long noncoding RNA NEAT1 knockdown inhibits MPP<sup>+</sup>-induced apoptosis, inο¬ammation and cytotoxicity in SK-N-SH cells by regulating miR-212-5p/RAB3IP axis. | Liu R et al. | β | 2020 | β |
| miR-433 Inhibits Neuronal Growth and Promotes Autophagy in Mouse Hippocampal HT-22 Cell Line. | Xu C et al. | β | 2020 | β |
| Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases. | John A et al. | β | 2020 | β |
| Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease. | Pascale E et al. | β | 2020 | β |
| Targeted sequencing of Parkinsonβs disease loci genes highlights<i>SYT11, FGF20</i>and other associations | Rudakou U et al. | β | 2020 | β |
| The Computational Analysis Conducted on miRNA Target Sites in Association with SNPs at 3'UTR of ADHD-implicated Genes. | Abdi A et al. | β | 2020 | β |
| Altered Expression Levels of MicroRNA-132 and Nurr1 in Peripheral Blood of Parkinson's Disease: Potential Disease Biomarkers. | Yang Z et al. | β | 2019 | β |
| A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites. | Fehlmann T et al. | β | 2019 | β |
| Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design. | De Franco S et al. | β | 2019 | β |
| Identification of biomarkers associated with Parkinson's disease by gene expression profiling studies and bioinformatics analysis. | Krokidis MG | β | 2019 | β |
| Implications of Fibroblast Growth Factors (FGFs) in Cancer: From Prognostic to Therapeutic Applications. | Dianat-Moghadam H et al. | β | 2019 | β |
| Involvement of aberrant regulation of epigenetic mechanisms in the pathogenesis of Parkinson's disease and epigenetic-based therapies. | Renani PG et al. | β | 2019 | β |
| Mesenchymal Stem Cells-derived Exosomes: A New Possible Therapeutic Strategy for Parkinson's Disease? | VilaΓ§a-Faria H et al. | β | 2019 | β |
| MicroRNA delivery through nanoparticles. | Lee SWL et al. | β | 2019 | β |
| MicroRNAs: Game Changers in the Regulation of <i>Ξ±</i>-Synuclein in Parkinson's Disease. | Zhao L et al. | β | 2019 | β |
| Nucleic Acid-Based Therapeutics for Parkinson's Disease. | Nakamori M et al. | β | 2019 | β |
| Precision Medicine in Neurodegenerative Diseases: Some Promising Tips Coming from the microRNAs' World. | Nuzziello N et al. | β | 2019 | β |
| Regulatory Mechanism of miR-543-3p on GLT-1 in a Mouse Model of Parkinson's Disease. | Wu X et al. | β | 2019 | β |
| Relationship between single nucleotide polymorphisms in the 3'UTR of amyloid precursor protein and risk of Alzheimer's disease and its mechanism. | Zhou Q et al. | β | 2019 | β |
| Systems biology and gene networks in Alzheimer's disease. | Wang ZT et al. | β | 2019 | β |
| Association of T/A polymorphism in miR-1302 binding site in CGA gene with male infertility in Isfahan population. | Jamalvandi M et al. | β | 2018 | β |
| CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks. | Li Y et al. | β | 2018 | β |
| Depressive symptoms are associated with a functional polymorphism in a miR-433 binding site in the FGF20 gene. | JimΓ©nez KM et al. | β | 2018 | β |
| Effects of rs591323 on serotonin transporter availability in healthy male subjects. | Pak K et al. | β | 2018 | β |
| Epigenetic mechanisms underlying nervous system diseases. | Qureshi IA et al. | β | 2018 | β |
| Evaluation of FGF 20 variants for susceptibility to Parkinson's disease in Eastern Indians. | Sadhukhan D et al. | β | 2018 | β |
| Identification of aberrant circulating miRNAs in Parkinson's disease plasma samples. | Chen L et al. | β | 2018 | β |
| Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with Ξ±-synuclein overexpression and risk of idiopathic Parkinson's disease. | Tarale P et al. | β | 2018 | β |
| Microarray Analysis of the Molecular Mechanism Involved in Parkinson's Disease. | Tan C et al. | β | 2018 | β |
| MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson's disease. | Yao L et al. | β | 2018 | β |
| MicroRNA expression patterns in human anterior cingulate and motor cortex: A study of dementia with Lewy bodies cases and controls. | Nelson PT et al. | β | 2018 | β |
| MicroRNAs in Post-traumatic Stress Disorder. | Snijders C et al. | β | 2018 | β |
| Neuroepigenetics of Aging and Age-Related Neurodegenerative Disorders. | Lardenoije R et al. | β | 2018 | β |
| Paraquat and MPTP alter microRNA expression profiles, and downregulated expression of miR-17-5p contributes to PQ-induced dopaminergic neurodegeneration. | Wang Q et al. | β | 2018 | β |
| Pervasive allele-specific regulation on RNA decay in hybrid mice. | Sun W et al. | β | 2018 | β |
| Potential dysfunctional effects of synonymous variants: Insights from an exhaustive in silico analysis of the ABCB4 gene. | Khabou B et al. | β | 2018 | β |
| Stress-induced changes in miRNA biogenesis and functioning. | Olejniczak M et al. | β | 2018 | β |
| The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution. | Krauskopf J et al. | β | 2018 | β |
| Amikacin Inhibits miR-497 Maturation and Exerts Post-ischemic Neuroprotection. | Sinoy S et al. | β | 2017 | β |
| An overview of circulating cell-free microRNAs as putative biomarkers in Alzheimer's and Parkinson's Diseases. | Batistela MS et al. | β | 2017 | β |
| Genetic analysis of FGF20 in Chinese patients with Parkinson's disease. | Sun XY et al. | β | 2017 | β |
| Genetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect? | RedenΕ‘ek S et al. | β | 2017 | β |
| Genetic Variants in SNCA and the Risk of Sporadic Parkinson's Disease and Clinical Outcomes: A Review. | CampΓͺlo CLDC et al. | β | 2017 | β |
| Identification of a New Single-nucleotide Polymorphism within the Apolipoprotein A5 Gene, Which is Associated with Metabolic Syndrome. | Salehi S et al. | β | 2017 | β |
| Identification of genome-wide non-canonical spliced regions and analysis of biological functions for spliced sequences using Read-Split-Fly. | Bai Y et al. | β | 2017 | β |
| MicroRNA Biomarkers in Neurodegenerative Diseases and Emerging Nano-Sensors Technology. | Shah P et al. | β | 2017 | β |
| MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian. | Mo M et al. | β | 2017 | β |
| MicroRNA expression signature of methamphetamine use and addiction in the rat nucleus accumbens. | Sim MS et al. | β | 2017 | β |
| MicroRNAs and Target Genes As Biomarkers for the Diagnosis of Early Onset of Parkinson Disease. | Arshad AR et al. | β | 2017 | β |
| MicroRNAs: Biomarkers, Diagnostics, and Therapeutics. | Huang W | β | 2017 | β |
| MicroRNAs in glaucoma and neurodegenerative diseases. | Molasy M et al. | β | 2017 | β |
| MicroRNAs in Parkinson's disease. | Singh A et al. | β | 2017 | β |
| microRNAs in Parkinson's Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches. | Leggio L et al. | β | 2017 | β |
| MiR-2964a-5p binding site SNP regulates <i>ATM</i> expression contributing to age-related cataract risk. | Rong H et al. | β | 2017 | β |
| miRNAs as biomarkers of neurodegenerative disorders. | Viswambharan V et al. | β | 2017 | β |
| Noncoding RNAs in neurodegeneration. | Salta E et al. | β | 2017 | β |
| Personalized genetics of the cholinergic blockade of neuroinflammation. | Simchovitz A et al. | β | 2017 | β |
| Reduced Circulating Levels of miR-433 and miR-133b Are Potential Biomarkers for Parkinson's Disease. | Zhang X et al. | β | 2017 | β |
| SNPs in microRNA target sites and their potential role in human disease. | MoszyΕska A et al. | β | 2017 | β |
| The Influence of Extracellular RNA on Cell Behavior in Health, Disease and Regeneration. | Huleihel L et al. | β | 2017 | β |
| The potential role of neuroinflammation and transcription factors in Parkinson disease. | Tiwari PC et al. | β | 2017 | β |
| The roles of RNA processing in translating genotype to phenotype. | Manning KS et al. | β | 2017 | β |
| The significance of microRNAs in the course of rDD. | BobiΕska K et al. | β | 2017 | β |
| The yin and yang of Ξ±-synuclein-associated epigenetics in Parkinson's disease. | Pavlou MAS et al. | β | 2017 | β |
| Tiny But Mighty: Promising Roles of MicroRNAs in the Diagnosis and Treatment of Parkinson's Disease. | Wang Y et al. | β | 2017 | β |
| Variants in SNCA Gene Are Associated with Parkinson's Disease Risk and Cognitive Symptoms in a Brazilian Sample. | CampΓͺlo CLC et al. | β | 2017 | β |
| Association between FGF20 rs12720208 gene polymorphism and Parkinson's disease: a meta-analysis. | Zhao X et al. | β | 2016 | β |
| Association of four new candidate genetic variants with Parkinson's disease in a Han Chinese population. | Wang L et al. | β | 2016 | β |
| Epigenetic regulation in Parkinson's disease. | LabbΓ© C et al. | β | 2016 | β |
| Estimating survival time of patients with glioblastoma multiforme and characterization of the identified microRNA signatures. | Yerukala Sathipati S et al. | β | 2016 | β |
| Genetic analysis of FGF20 variants in Chinese Han patients with essential tremor. | Yuan L et al. | β | 2016 | β |
| High production in E. coli of biologically active recombinant human fibroblast growth factor 20 and its neuroprotective effects. | Tian H et al. | β | 2016 | β |
| microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases. | Basak I et al. | β | 2016 | β |
| microRNAs involved in Parkinson's disease: A systematic review. | da Silva FC et al. | β | 2016 | β |
| MicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological Diseases. | Cao DD et al. | β | 2016 | β |
| miR-148b-3p promotes migration of Schwann cells by targeting cullin-associated and neddylation-dissociated 1. | Qian TM et al. | β | 2016 | β |
| MiRNA expression profiles in the brains of mice infected with scrapie agents 139A, ME7 and S15. | Gao C et al. | β | 2016 | β |
| Neuroprotective Role of MicroRNA-22 in a 6-Hydroxydopamine-Induced Cell Model of Parkinson's Disease via Regulation of Its Target Gene TRPM7. | Yang CP et al. | β | 2016 | β |
| Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production. | Wu C et al. | β | 2016 | β |
| Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity. | Tarale P et al. | β | 2016 | β |
| Role of microRNAs in the Regulation of Ξ±-Synuclein Expression: A Systematic Review. | Recasens A et al. | β | 2016 | β |
| Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson's disease. | Pal R et al. | β | 2016 | β |
| The roles of non-coding RNAs in Parkinson's disease. | Majidinia M et al. | β | 2016 | β |
| Vulnerability of microRNA biogenesis in FTD-ALS. | Eitan C et al. | β | 2016 | β |
| Angiogenesis-regulating microRNAs and Ischemic Stroke. | Yin KJ et al. | β | 2015 | β |
| An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1Ξ± 3'-untranslated region is associated with a risk for osteoarthritis. | Yang F et al. | β | 2015 | β |
| Body mass index associated to rs2021966 ENPP1 polymorphism increases the risk for gestational diabetes mellitus. | Tarquini F et al. | β | 2015 | β |
| Causes and Consequences of MicroRNA Dysregulation in Neurodegenerative Diseases. | Tan L et al. | β | 2015 | β |
| Formation of covalent di-tyrosine dimers in recombinant Ξ±-synuclein. | van Maarschalkerweerd A et al. | β | 2015 | β |
| Frequencies of single-nucleotide polymorphisms and haplotypes of the SLCO1B1 gene in selected populations of the western balkans. | Grapci AD et al. | β | 2015 | β |
| Genetic variability of microRNA regulome in human. | Obsteter J et al. | β | 2015 | β |
| Identification of age- and disease-related alterations in circulating miRNAs in a mouse model of Alzheimer's disease. | Garza-Manero S et al. | β | 2015 | β |
| Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. | Niu T et al. | β | 2015 | β |
| Inhibition of miR-34b and miR-34c enhances Ξ±-synuclein expression in Parkinson's disease. | Kabaria S et al. | β | 2015 | β |
| Meta gene set enrichment analyses link miR-137-regulated pathways with schizophrenia risk. | Wright C et al. | β | 2015 | β |
| MicroRNA-214 participates in the neuroprotective effect of Resveratrol via inhibiting Ξ±-synuclein expression in MPTP-induced Parkinson's disease mouse. | Wang ZH et al. | β | 2015 | β |
| MicroRNA association with synucleinopathy conversion in rapid eye movement behavior disorder. | FernΓ‘ndez-Santiago R et al. | β | 2015 | β |
| Midbrain dopamine neurons in Parkinson's disease exhibit a dysregulated miRNA and target-gene network. | Briggs CE et al. | β | 2015 | β |
| miRNAs: Key Players in Neurodegenerative Disorders and Epilepsy. | Karnati HK et al. | β | 2015 | β |
| Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2Ξ± Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population. | Xiao B et al. | β | 2015 | β |
| The epigenetics of aging and neurodegeneration. | Lardenoije R et al. | β | 2015 | β |
| The role of RNA metabolism in neurological diseases. | Alaqeel AM et al. | β | 2015 | β |
| Variation in the miRNA-433 binding site of FGF20 is a risk factor for Parkinson's disease in Iranian population. | Haghnejad L et al. | β | 2015 | β |
| Accessibility of microRNA binding sites in metastable RNA secondary structures in the presence of SNPs. | Day L et al. | β | 2014 | β |
| A genetic variant in microRNA target site of TGF-Ξ² signaling pathway increases the risk of colorectal cancer in a Chinese population. | Gong J et al. | β | 2014 | β |
| Analysis of microRNA from archived formalin-fixed paraffin-embedded specimens of amyotrophic lateral sclerosis. | Wakabayashi K et al. | β | 2014 | β |
| Bioinformatic prediction of SNPs within miRNA binding sites of inflammatory genes associated with gastric cancer. | Song CQ et al. | β | 2014 | β |
| Cis-regulatory variation: significance in biomedicine and evolution. | Friedensohn S et al. | β | 2014 | β |
| Computational prediction of microRNAs from Toxoplasma gondii potentially regulating the hosts' gene expression. | SaΓ§ar MD et al. | β | 2014 | β |
| Congenital heart disease: the crossroads of genetics, epigenetics and environment. | Vecoli C et al. | β | 2014 | β |
| Emerging therapies for Parkinson's disease: from bench to bedside. | Tarazi FI et al. | β | 2014 | β |
| Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases. | Qureshi IA et al. | β | 2014 | β |
| FGF receptors: cancer biology and therapeutics. | Katoh M et al. | β | 2014 | β |
| Fibroblast growth factor 20 (FGF20) gene polymorphism and risk of Parkinson's disease: a meta-analysis. | Zhu R et al. | β | 2014 | β |
| Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites. | Wu D et al. | β | 2014 | β |
| Identification of blood serum micro-RNAs associated with idiopathic and LRRK2 Parkinson's disease. | Botta-Orfila T et al. | β | 2014 | β |
| MicroRNA expression profiles in supraglottic carcinoma. | Zhang T et al. | β | 2014 | β |
| MicroRNAs: Important Epigenetic Regulators in Osteoarthritis. | Trzeciak T et al. | β | 2014 | β |
| MicroRNAs targeting Nicastrin regulate AΞ² production and are affected by target site polymorphisms. | Delay C et al. | β | 2014 | β |
| Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders. | Maffioletti E et al. | β | 2014 | β |
| Mining the 3'UTR of autism-implicated genes for SNPs perturbing microRNA regulation. | Vaishnavi V et al. | β | 2014 | β |
| miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling. | Kim W et al. | β | 2014 | β |
| miRNA gene counts in chromosomes vary widely in a species and biogenesis of miRNA largely depends on transcription or post-transcriptional processing of coding genes. | Ghorai A et al. | β | 2014 | β |
| MiRNA profile in the substantia nigra of Parkinson's disease and healthy subjects. | Cardo LF et al. | β | 2014 | β |
| miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions. | Hsu SD et al. | β | 2014 | β |
| Neuroprotection of microRNA in neurological disorders (Review). | Wang C et al. | β | 2014 | β |
| Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease. | Schlaudraff F et al. | β | 2014 | β |
| PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways. | Bhattacharya A et al. | β | 2014 | β |
| Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology. | Burgos K et al. | β | 2014 | β |
| Role of genomics in translational research for Parkinson's disease. | Sekiyama K et al. | β | 2014 | β |
| The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease. | Williams AJ et al. | β | 2014 | β |
| The role of microRNAs in human diseases. | TΓΌfekci KU et al. | β | 2014 | β |
| Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. | Ubhi K et al. | β | 2014 | β |
| Advances with microRNAs in Parkinson's disease research. | Ma L et al. | β | 2013 | β |
| A mir-153 binding site variation in SNCA in a patient with Parkinson's disease. | Kim HJ et al. | β | 2013 | β |
| CNR1 variation is associated with the age at onset in Huntington disease. | Kloster E et al. | β | 2013 | β |
| EGFR 3'UTR 774T>C polymorphism contributes to bladder cancer risk. | Chu H et al. | β | 2013 | β |
| Emerging roles for miRNAs in the development, diagnosis, and treatment of diabetic nephropathy. | DiStefano JK et al. | β | 2013 | β |
| Epigenetic landscape of Parkinson's disease: emerging role in disease mechanisms and therapeutic modalities. | Ammal Kaidery N et al. | β | 2013 | β |
| Epigenetics in Parkinson's and Alzheimer's diseases. | Marques S et al. | β | 2013 | β |
| Evaluation of single nucleotide polymorphisms in the miR-183-96-182 cluster in adulthood attention-deficit and hyperactivity disorder (ADHD) and substance use disorders (SUDs). | SΓ‘nchez-Mora C et al. | β | 2013 | β |
| Fibroblast growth factor 20 polymorphism in sporadic Parkinson's disease in Northern Han Chinese. | Xu X et al. | β | 2013 | β |
| Genetic variation in a microRNA-502 minding site in SET8 gene confers clinical outcome of non-small cell lung cancer in a Chinese population. | Xu J et al. | β | 2013 | β |
| Genomic and epigenomic insights into nutrition and brain disorders. | Dauncey MJ | β | 2013 | β |
| MicroRNAs and Molecular Mechanisms of Neurodegeneration. | Bicchi I et al. | β | 2013 | β |
| microRNAs and the regulation of neuronal plasticity under stress conditions. | Schouten M et al. | β | 2013 | β |
| miRNA-9 expression is upregulated in the spinal cord of G93A-SOD1 transgenic mice. | Zhou F et al. | β | 2013 | β |
| miRNA in the regulation of ion channel/transporter expression. | Wang Z | β | 2013 | β |
| Molecular mechanisms of peripheral nerve regeneration: emerging roles of microRNAs. | Wu D et al. | β | 2013 | β |
| Mood stabilizer-regulated miRNAs in neuropsychiatric and neurodegenerative diseases: identifying associations and functions. | Hunsberger JG et al. | β | 2013 | β |
| Mutational screening of PARKIN identified a 3' UTR variant (rs62637702) associated with Parkinson's disease. | de Mena L et al. | β | 2013 | β |
| Neuronal dark matter: the emerging role of microRNAs in neurodegeneration. | Goodall EF et al. | β | 2013 | β |
| Neuronal nicotinic receptor agonists ameliorate spontaneous motor asymmetries and motor discoordination in a unilateral mouse model of Parkinson's disease. | Kucinski A et al. | β | 2013 | β |
| Noncoding RNAs in Neurodegenerative Diseases. | Rege SD et al. | β | 2013 | β |
| Polymorphisms in lipid metabolism related miRNA binding sites and risk of metabolic syndrome. | Ye Q et al. | β | 2013 | β |
| Profile of microRNAs in the plasma of Parkinson's disease patients and healthy controls. | Cardo LF et al. | β | 2013 | β |
| REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. | Zhang S et al. | β | 2013 | β |
| Roles of FGF20 in dopaminergic neurons and Parkinson's disease. | Itoh N et al. | β | 2013 | β |
| SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers. | Preskill C et al. | β | 2013 | β |
| The involvement of microRNAs in neurodegenerative diseases. | Maciotta S et al. | β | 2013 | β |
| The polymorphism in the let-7 targeted region of the Lin28 gene is associated with increased risk of type 2 diabetes mellitus. | Zhang J et al. | β | 2013 | β |
| Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction. | MiΓ±ones-Moyano E et al. | β | 2013 | β |
| Allele specific expression of the transthyretin gene in swedish patients with hereditary transthyretin amyloidosis (ATTR V30M) is similar between the two alleles. | Norgren N et al. | β | 2012 | β |
| A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy. | Papagregoriou G et al. | β | 2012 | β |
| An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model. | Selvamani A et al. | β | 2012 | β |
| A search for SNCA 3' UTR variants identified SNP rs356165 as a determinant of disease risk and onset age in Parkinson's disease. | Cardo LF et al. | β | 2012 | β |
| Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease. | Collins LM et al. | β | 2012 | β |
| Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration. | Singh M | β | 2012 | β |
| Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. | Qureshi IA et al. | β | 2012 | β |
| Epigenetic programming of neurodegenerative diseases by an adverse environment. | Babenko O et al. | β | 2012 | β |
| Fibroblast growth factor-20 protects against dopamine neuron loss inΒ vitro and provides functional protection in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease. | Sleeman IJ et al. | β | 2012 | β |
| Genetics and epigenetics of Parkinson's disease. | CoppedΓ¨ F | β | 2012 | β |
| Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis. | Gong J et al. | β | 2012 | β |
| Genome-wide SNP scan of pooled DNA reveals nonsense mutation in FGF20 in the scaleless line of featherless chickens. | Wells KL et al. | β | 2012 | β |
| Lack of association of polymorphism in miRNA-196a2 with Parkinson's disease risk in a Chinese population. | Haixia D et al. | β | 2012 | β |
| MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects. | Smalheiser NR et al. | β | 2012 | β |
| MicroRNAs in brain development and degeneration. | Enciu AM et al. | β | 2012 | β |
| MicroRNAs in learning, memory, and neurological diseases. | Wang W et al. | β | 2012 | β |
| MicroRNAs in neurodegenerative diseases and their therapeutic potential. | Junn E et al. | β | 2012 | β |
| MicroRNAs in Neurotoxicity. | Kaur P et al. | β | 2012 | β |
| MicroRNAs in Parkinson's disease. | Mouradian MM | β | 2012 | β |
| MicroRNAs: possible role in pathogenesis of Parkinson's disease. | Filatova EV et al. | β | 2012 | β |
| miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes. | Bruno AE et al. | β | 2012 | β |
| miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines. | Zhang W et al. | β | 2012 | β |
| miRNAs and their putative roles in the development and progression of Parkinson's disease. | Wong G et al. | β | 2012 | β |
| Neurochemistry and the non-motor aspects of PD. | Ferrer I et al. | β | 2012 | β |
| Neurodegeneration as an RNA disorder. | Johnson R et al. | β | 2012 | β |
| Non-coding RNAs with essential roles in neurodegenerative disorders. | Salta E et al. | β | 2012 | β |
| Novel microRNAs differentially expressed during aging in the mouse brain. | Inukai S et al. | β | 2012 | β |
| PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits. | Ziebarth JD et al. | β | 2012 | β |
| Rodent models and contemporary molecular techniques: notable feats yet incomplete explanations of Parkinson's disease pathogenesis. | Yadav S et al. | β | 2012 | β |
| Role of microRNAs in central nervous system development and pathology. | Meza-Sosa KF et al. | β | 2012 | β |
| Systematic analysis of microRNA targeting impacted by small insertions and deletions in human genome. | Bhattacharya A et al. | β | 2012 | β |
| The Impact of MicroRNAs on Brain Aging and Neurodegeneration. | Persengiev SP et al. | β | 2012 | β |
| Time is of the essence: microRNAs and age-associated neurodegeneration. | Aw S et al. | β | 2012 | β |
| Transcriptome analysis of microRNAs in developing cerebral cortex of rat. | Yao MJ et al. | β | 2012 | β |
| Variants in the 3'UTR of SNCA do not affect miRNA-433 binding and alpha-synuclein expression. | Schmitt I et al. | β | 2012 | β |
| Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function. | Delay C et al. | β | 2011 | β |
| Amyloid precursor protein gene (APP) variation in late-onset Alzheimer's disease. | Miar A et al. | β | 2011 | β |
| ATP6V0A1 polymorphism and microRNA-637: A pathogenetic role for microRNAs in essential hypertension at last? | Contu R et al. | β | 2011 | β |
| A two-stage meta-analysis identifies several new loci for Parkinson's disease. | International Parkinson's Disease Genomics Consortium (IPDGC) et al. | β | 2011 | β |
| Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain. | Favereaux A et al. | β | 2011 | β |
| Convergence of miRNA expression profiling, Ξ±-synuclein interacton and GWAS in Parkinson's disease. | Martins M et al. | β | 2011 | β |
| Effects of temperature and additives on stability and spectrum of a therapeutic fibroblast growth factor. | Zhou C et al. | β | 2011 | β |
| From cradle to grave: the multiple roles of fibroblast growth factors in neural development. | Guillemot F et al. | β | 2011 | β |
| Functions of noncoding RNAs in neural development and neurological diseases. | Bian S et al. | β | 2011 | β |
| Gene therapy: a viable therapeutic strategy for Parkinson's disease? | Berry AL et al. | β | 2011 | β |
| Identification of blood microRNAs associated to ParkinsonΔs disease. | Margis R et al. | β | 2011 | β |
| Inferring causative variants in microRNA target sites. | Thomas LF et al. | β | 2011 | β |
| Interactions of formulation excipients with proteins in solution and in the dried state. | Ohtake S et al. | β | 2011 | β |
| MicroRNA function in the nervous system. | Fiore R et al. | β | 2011 | β |
| MicroRNA: implications in HIV, a brief overview. | Pilakka-Kanthikeel S et al. | β | 2011 | β |
| MicroRNA in central nervous system trauma and degenerative disorders. | Liu NK et al. | β | 2011 | β |
| MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. | MiΓ±ones-Moyano E et al. | β | 2011 | β |
| MicroRNAs in development and disease. | Sayed D et al. | β | 2011 | β |
| MicroRNAs in Experimental Models of Movement Disorders. | Lee ST et al. | β | 2011 | β |
| MicroRNAs in Parkinson's disease. | Harraz MM et al. | β | 2011 | β |
| MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. | Xu N et al. | β | 2011 | β |
| Neuropathology and neurochemistry of nonmotor symptoms in Parkinson's disease. | Ferrer I | β | 2011 | β |
| Non-coding RNAs in human disease. | Esteller M | β | 2011 | β |
| Polymorphisms affecting micro-RNA regulation and associated with the risk of dietary-related cancers: a review from the literature and new evidence for a functional role of rs17281995 (CD86) and rs1051690 (INSR), previously associated with colorectal cancer. | Landi D et al. | β | 2011 | β |
| Polymorphisms in predicted miRNA binding sites and osteoporosis. | Lei SF et al. | β | 2011 | β |
| Sequence variants within the 3'-UTR of the COL5A1 gene alters mRNA stability: implications for musculoskeletal soft tissue injuries. | Laguette MJ et al. | β | 2011 | β |
| Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy. | Heinzle C et al. | β | 2011 | β |
| The AVPR1A gene and substance use disorders: association, replication, and functional evidence. | Maher BS et al. | β | 2011 | β |
| The Influence of 3'UTRs on MicroRNA Function Inferred from Human SNP Data. | Hu Z et al. | β | 2011 | β |
| The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy. | Sibley CR et al. | β | 2011 | β |
| Tiny non-coding RNAs in Parkinson's disease: implications, expectations and hypes. | Srivastava G et al. | β | 2011 | β |
| Vitamin D receptor gene as a candidate gene for Parkinson disease. | Butler MW et al. | β | 2011 | β |
| A functional variant in the 3'-UTR of angiopoietin-1 might reduce stroke risk by interfering with the binding efficiency of microRNA 211. | Chen J et al. | β | 2010 | β |
| A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia. | Simon D et al. | β | 2010 | β |
| A myriad of miRNA variants in control and Huntington's disease brain regions detected by massively parallel sequencing. | MartΓ E et al. | β | 2010 | β |
| Analysis of the Micro-RNA-133 and PITX3 genes in Parkinson's disease. | de Mena L et al. | β | 2010 | β |
| A novel statistic for genome-wide interaction analysis. | Wu X et al. | β | 2010 | β |
| Demonstrating polymorphic miRNA-mediated gene regulation in vivo: application to the g+6223G->A mutation of Texel sheep. | Takeda H et al. | β | 2010 | β |
| Design and evaluation of a panel of single-nucleotide polymorphisms in microRNA genomic regions for association studies in human disease. | MuiΓ±os-Gimeno M et al. | β | 2010 | β |
| Dysregulated microRNAs in neurodegenerative disorders. | Lau P et al. | β | 2010 | β |
| FGF20 rs12720208 SNP and microRNA-433 variation: no association with Parkinson's disease in Spanish patients. | de Mena L et al. | β | 2010 | β |
| Genetics of Parkinson disease and essential tremor. | Wider C et al. | β | 2010 | β |
| Genetic variation in FGF20 modulates hippocampal biology. | Lemaitre H et al. | β | 2010 | β |
| Manganese induces the overexpression of Ξ±-synuclein in PC12 cells via ERK activation. | Cai T et al. | β | 2010 | β |
| MicroRNA let-7: an emerging next-generation cancer therapeutic. | Barh D et al. | β | 2010 | β |
| MicroRNAs and deregulated gene expression networks in neurodegeneration. | Sonntag KC | β | 2010 | β |
| MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. | Xu Y et al. | β | 2010 | β |
| MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration. | Saugstad JA | β | 2010 | β |
| microRNAs in diseases: from candidate to modifier genes. | Bandiera S et al. | β | 2010 | β |
| MicroRNAs in neuronal development, function and dysfunction. | Saba R et al. | β | 2010 | β |
| MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets. | Barenboim M et al. | β | 2010 | β |
| miRNA mutations are not a common cause of deafness. | Hildebrand MS et al. | β | 2010 | β |
| Molecular mechanisms of pathogenesis of Parkinson's disease. | Shadrina MI et al. | β | 2010 | β |
| Parkinson's disease: Exit toxins, enter genetics. | Westerlund M et al. | β | 2010 | β |
| Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates. | Hiard S et al. | β | 2010 | β |
| RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform. | Bennett CF et al. | β | 2010 | β |
| Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. | MuiΓ±os-Gimeno M et al. | β | 2009 | β |
| Alterations of the microRNA network cause neurodegenerative disease. | HΓ©bert SS et al. | β | 2009 | β |
| An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma. | Gao Y et al. | β | 2009 | β |
| An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. | Song F et al. | β | 2009 | β |
| Association of variants in MANEA with cocaine-related behaviors. | Farrer LA et al. | β | 2009 | β |
| Autism Genetic Database (AGD): a comprehensive database including autism susceptibility gene-CNVs integrated with known noncoding RNAs and fragile sites. | Matuszek G et al. | β | 2009 | β |
| Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. | Levy OA et al. | β | 2009 | β |
| Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer. | TabarΓ©s-Seisdedos R et al. | β | 2009 | β |
| Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. | Duan S et al. | β | 2009 | β |
| Etiopathogenesis of Parkinson disease: a new beginning? | Weidong Le et al. | β | 2009 | β |
| FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression. | Wider C et al. | β | 2009 | β |
| FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies. | Katoh M | β | 2009 | β |
| Lack of association between endothelin-1 gene variants and myocardial infarction. | PalacΓn M et al. | β | 2009 | β |
| Mapping of solution components, pH changes, protein stability and the elimination of protein precipitation during freeze-thawing of fibroblast growth factor 20. | Maity H et al. | β | 2009 | β |
| Medicine. A reinnervating microRNA. | Brown RH | β | 2009 | β |
| microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells. | Weitzel RP et al. | β | 2009 | β |
| MicroRNA expression changes in lymphoblastoid cell lines in response to lithium treatment. | Chen H et al. | β | 2009 | β |
| MicroRNA implications across neurodevelopment and neuropathology. | Martino S et al. | β | 2009 | β |
| MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders. | Maes OC et al. | β | 2009 | β |
| microRNA involvement in developmental and functional aspects of the nervous system and in neurological diseases. | Christensen M et al. | β | 2009 | β |
| MicroRNA polymorphisms: a giant leap towards personalized medicine. | Mishra PJ | β | 2009 | β |
| MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. | Mishra PJ et al. | β | 2009 | β |
| MicroRNA regulation of Alzheimer's Amyloid precursor protein expression. | HΓ©bert SS et al. | β | 2009 | β |
| microRNAs in CNS disorders. | Kocerha J et al. | β | 2009 | β |
| microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity. | Chandrasekar V et al. | β | 2009 | β |
| MicroRNAs: novel therapeutic targets in neurodegenerative diseases. | Roshan R et al. | β | 2009 | β |
| miR-155 gene: a typical multifunctional microRNA. | Faraoni I et al. | β | 2009 | β |
| miR2Disease: a manually curated database for microRNA deregulation in human disease. | Jiang Q et al. | β | 2009 | β |
| miRΓ²: a miRNA knowledge base. | LaganΓ A et al. | β | 2009 | β |
| Molecular pathology of the fibroblast growth factor family. | Krejci P et al. | β | 2009 | β |
| Next generation tools for the annotation of human SNPs. | Karchin R | β | 2009 | β |
| Repression of alpha-synuclein expression and toxicity by microRNA-7. | Junn E et al. | β | 2009 | β |
| Searching for MIND: microRNAs in neurodegenerative diseases. | Barbato C et al. | β | 2009 | β |
| Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeutics. | Weinberg MS et al. | β | 2009 | β |
| The FGF family: biology, pathophysiology and therapy. | Beenken A et al. | β | 2009 | β |
| The impact of microRNAs and alternative splicing in pharmacogenomics. | Passetti F et al. | β | 2009 | β |
| The therapeutic potential of microRNAs in nervous system damage, degeneration, and repair. | Hutchison ER et al. | β | 2009 | β |
| Understanding microRNAs in neurodegeneration. | Eacker SM et al. | β | 2009 | β |
| A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. | Mellios N et al. | β | 2008 | β |
| Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease. | Mizuta I et al. | β | 2008 | β |
| Cerebellar alpha-synuclein levels are decreased in Parkinson's disease and do not correlate with SNCA polymorphisms associated with disease in a Swedish material. | Westerlund M et al. | β | 2008 | β |
| Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome. | Pezzolesi MG et al. | β | 2008 | β |
| Epigenetic principles and mechanisms underlying nervous system functions in health and disease. | Mehler MF | β | 2008 | β |
| Functional genetic variation of human miRNAs and phenotypic consequences. | Borel C et al. | β | 2008 | β |
| Genes associated with Parkinson syndrome. | Biskup S et al. | β | 2008 | β |
| Genome-wide analysis of natural selection on human cis-elements. | Sethupathy P et al. | β | 2008 | β |
| MicroRNA target site polymorphisms and human disease. | Sethupathy P et al. | β | 2008 | β |
| The microRNA pathway and fragile X mental retardation protein. | Li Y et al. | β | 2008 | β |