Common genetic variation and human traits.
paper
Cited
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- Authors
- Goldstein, David B
- Year
- 2009
- Journal
- The New England journal of medicine
- PMID
- 19369660
- DOI
- 10.1056/NEJMp0806284
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|---|---|---|---|---|
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| Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery. | Dudley JT et al. | — | 2012 | → |
| Family studies in Crohn's disease: new horizons in understanding disease pathogenesis, risk and prevention. | Hedin CR et al. | — | 2012 | → |
| Fast identification of biological pathways associated with a quantitative trait using group lasso with overlaps. | Silver M et al. | — | 2012 | → |
| Functional analysis of HapMap SNPs. | Liu CT et al. | — | 2012 | → |
| Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS). | Lahiri DK et al. | — | 2012 | → |
| Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach. | Fardo DW et al. | — | 2012 | → |
| Gene expression as a quantitative trait: what about translation? | Polychronakos C | — | 2012 | → |
| Genetic markers for ovarian cancer risk: are we close to seeing a clinical impact? | Moorman PG | — | 2012 | → |
| Genetic variability in molecular responses to chemical exposure. | Patel CJ et al. | — | 2012 | → |
| Genome-wide approaches in pharmacogenomics: heritability estimation and pharmacoethnicity as primary challenges. | Gamazon ER et al. | — | 2012 | → |
| Genome-wide association studies (GWAS) in complex diseases: advantages and limitations. | Riancho JA | — | 2012 | → |
| Genome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers. | Oved K et al. | — | 2012 | → |
| Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics. | Valencia A et al. | — | 2012 | → |
| Hereditary ovarian cancer: beyond the usual suspects. | Pennington KP et al. | — | 2012 | → |
| Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms. | Barrenäs F et al. | — | 2012 | → |
| High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions. | Fang G et al. | — | 2012 | → |
| HLA Immune Function Genes in Autism. | Torres AR et al. | — | 2012 | → |
| Homo sapiens, Homo neanderthalensis and the Denisova specimen: New insights on their evolutionary histories using whole-genome comparisons. | Paixão-Côrtes VR et al. | — | 2012 | → |
| Host genomics and HCV treatment response. | Clark PJ et al. | — | 2012 | → |
| How accurate can genetic predictions be? | Dreyfuss JM et al. | — | 2012 | → |
| Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum. | Hitomi Y et al. | — | 2012 | → |
| Identification of genes affecting apolipoprotein B secretion following siRNA-mediated gene knockdown in primary human hepatocytes. | Shen X et al. | — | 2012 | → |
| Insights into Assessing the Genetics of Endometriosis. | Rahmioglu N et al. | — | 2012 | → |
| Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. | Diamanti-Kandarakis E et al. | — | 2012 | → |
| Integrative approaches for microarray data analysis. | Waldron L et al. | — | 2012 | → |
| Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity. | Tovo-Rodrigues L et al. | — | 2012 | → |
| Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease? | Zintzaras E | — | 2012 | → |
| Leveraging models of cell regulation and GWAS data in integrative network-based association studies. | Califano A et al. | — | 2012 | → |
| Likelihood approach for detecting imprinting and in utero maternal effects using general pedigrees from prospective family-based association studies. | Yang J et al. | — | 2012 | → |
| 'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate. | Fier H et al. | — | 2012 | → |
| Lost in translation? IL28B's discovery and the journey back to the patient. | Clark PJ et al. | — | 2012 | → |
| Mechanisms of age-related macular degeneration. | Ambati J et al. | — | 2012 | → |
| Metabolic reconstruction for metagenomic data and its application to the human microbiome. | Abubucker S et al. | — | 2012 | → |
| NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in Canadian children and young adults. | Amre DK et al. | — | 2012 | → |
| Pain genetics: past, present and future. | Mogil JS | — | 2012 | → |
| Personalised medicine: not just in our genes. | Kitsios GD et al. | — | 2012 | → |
| Personalized medicine: hope or hype? | Salari K et al. | — | 2012 | → |
| Pharmacogenetics and anaesthesia: the value of genetic profiling. | Landau R et al. | — | 2012 | → |
| Prostate cancer: germline prediction for a commonly variable malignancy. | Bambury RM et al. | — | 2012 | → |
| Public funding for genomics: where does Canada stand? | Polychronakos C | — | 2012 | → |
| Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height. | Williams PT | — | 2012 | → |
| Reverse-engineering human regulatory networks. | Lefebvre C et al. | — | 2012 | → |
| The changing landscape of genetic testing and its impact on clinical and laboratory services and research in Europe. | Hastings R et al. | — | 2012 | → |
| The gene in its natural habitat: the importance of gene-trait interactions. | DeYoung CG et al. | — | 2012 | → |
| The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE. | Guerreiro RJ et al. | — | 2012 | → |
| The genetic architecture of schizophrenia: new mutations and emerging paradigms. | Rodriguez-Murillo L et al. | — | 2012 | → |
| The mystery of missing heritability: Genetic interactions create phantom heritability. | Zuk O et al. | — | 2012 | → |
| The myth of genetic enhancement. | Rosoff PM | — | 2012 | → |
| The stroke-prone spontaneously hypertensive rat: still a useful model for post-GWAS genetic studies? | Nabika T et al. | — | 2012 | → |
| TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. | Gregory AP et al. | — | 2012 | → |
| Transgenerational defense induction and epigenetic inheritance in plants. | Holeski LM et al. | — | 2012 | → |
| Uromodulin in kidney injury: an instigator, bystander, or protector? | El-Achkar TM et al. | — | 2012 | → |
| Using graded response model for the prediction of prostate cancer risk. | Chen SH et al. | — | 2012 | → |
| Accurate estimation of heritability in genome wide studies using random effects models. | Golan D et al. | — | 2011 | → |
| A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. | Wu R et al. | — | 2011 | → |
| A fast algorithm to optimize SNP prioritization for gene-gene and gene-environment interactions. | Deng WQ et al. | — | 2011 | → |
| A functional alternative splicing mutation in human tryptophan hydroxylase-2. | Zhang X et al. | — | 2011 | → |
| Alzheimer's disease genetics: current knowledge and future challenges. | Hollingworth P et al. | — | 2011 | → |
| An exposure driven functional model of carcinogenesis. | Lund E | — | 2011 | → |
| A novel method to detect rare variants using both family and unrelated case-control data. | Feng T et al. | — | 2011 | → |
| A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. | Heath AC et al. | — | 2011 | → |
| Assessing the contribution family data can make to case-control studies of rare variants. | Curtis D | — | 2011 | → |
| Association genetics of complex traits in plants. | Ingvarsson PK et al. | — | 2011 | → |
| Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals. | Thalamuthu A et al. | — | 2011 | → |
| A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis. | Nakaoka H et al. | — | 2011 | → |
| Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies. | Miossec P et al. | — | 2011 | → |
| Brain expression quantitative trait locus mapping informs genetic studies of psychiatric diseases. | Liu C | — | 2011 | → |
| Bridging autism, science and society: moving toward an ethically informed approach to autism research. | Pellicano E et al. | — | 2011 | → |
| Classifying personality disorders: an evolution-based alternative to an evidence-based approach. | Millon T | — | 2011 | → |
| Common and rare variants in alcohol dependence. | Edenberg HJ | — | 2011 | → |
| Comparison of methods and sampling designs to test for association between rare variants and quantitative traits. | Bacanu SA et al. | — | 2011 | → |
| Con: Genome-wide association studies have not been useful in understanding asthma. | Adcock IM et al. | — | 2011 | → |
| Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients. | Bonilla C et al. | — | 2011 | → |
| Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis. | Yazbek SN et al. | — | 2011 | → |
| Detecting low frequent loss-of-function alleles in genome wide association studies with red hair color as example. | Liu F et al. | — | 2011 | → |
| Different differences: the use of 'genetic ancestry' versus race in biomedical human genetic research. | Fujimura JH et al. | — | 2011 | → |
| Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits? | Lamina C | — | 2011 | → |
| Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma. | Koo YX et al. | — | 2011 | → |
| Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures. | Doehring A et al. | — | 2011 | → |
| Environment-sensitive epigenetics and the heritability of complex diseases. | Furrow RE et al. | — | 2011 | → |
| Finding disease genes: a fast and flexible approach for analyzing high-throughput data. | Stewart WC et al. | — | 2011 | → |
| Four out of eight genes in a mouse chromosome 7 congenic donor region are candidate obesity genes. | Sarahan KA et al. | — | 2011 | → |
| Further thoughts on the relation of personality and psychopathology. | Millon T | — | 2011 | → |
| Gastrointestinal and liver diseases: genetic and epigenetic markers. | Blum HE | — | 2011 | → |
| Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. | Daly AK et al. | — | 2011 | → |
| Genetic factors in contact allergy--review and future goals. | Schnuch A et al. | — | 2011 | → |
| Genetic predisposition to autoimmunity--what have we learned? | Rai E et al. | — | 2011 | → |
| Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies. | Obeidat M et al. | — | 2011 | → |
| Genetics of emotion. | Bevilacqua L et al. | — | 2011 | → |
| Genetics of infectious diseases: hidden etiologies and common pathways. | Orlova M et al. | — | 2011 | → |
| Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities. Background Document to the ESHG recommendations on genetic testing and common disorders. | Becker F et al. | — | 2011 | → |
| Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes. | Sharma S et al. | — | 2011 | → |
| Genome-wide association studies of atrial fibrillation: past, present, and future. | Sinner MF et al. | — | 2011 | → |
| Genome-wide association studies of sleep disorders. | Raizen DM et al. | — | 2011 | → |
| Genome-wide expression profiling of human lymphoblastoid cell lines identifies CHL1 as a putative SSRI antidepressant response biomarker. | Morag A et al. | — | 2011 | → |
| Genomics in the post-GWAS era. | Juran BD et al. | — | 2011 | → |
| Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. | Leikauf GD et al. | — | 2011 | → |
| High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome. | Wilke RA | — | 2011 | → |
| Human genetic susceptibility to intracellular pathogens. | Vannberg FO et al. | — | 2011 | → |
| Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. | Casanova JL et al. | — | 2011 | → |
| IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies. | Clark PJ et al. | — | 2011 | → |
| IL28B single nucleotide polymorphisms in the treatment of hepatitis C. | Lange CM et al. | — | 2011 | → |
| Inflammatory bowel disease: recent advances on genetics and innate immunity. | Karantanos T et al. | — | 2011 | → |
| Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load. | Vasunilashorn S et al. | — | 2011 | → |
| Inherited destiny? Genetics and gestational diabetes mellitus. | Watanabe RM | — | 2011 | → |
| Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function. | Hitomi Y et al. | — | 2011 | → |
| Interest in genetic testing for modest changes in breast cancer risk: implications for SNP testing. | Graves KD et al. | — | 2011 | → |
| Interspecies translation of disease networks increases robustness and predictive accuracy. | Anvar SY et al. | — | 2011 | → |
| Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. | Turner SD et al. | — | 2011 | → |
| LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects. | Balistreri CR et al. | — | 2011 | → |
| Modeling of environmental and genetic interactions with AMBROSIA, an information-theoretic model synthesis method. | Chanda P et al. | — | 2011 | → |
| Monogenic atrial fibrillation as pathophysiological paradigms. | Mahida S et al. | — | 2011 | → |
| Network medicine: a network-based approach to human disease. | Barabási AL et al. | — | 2011 | → |
| Newly diagnosed epilepsy and pharmacogenomics research: a step in the right direction? | Johnson MR et al. | — | 2011 | → |
| Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. | Hoffmann TJ et al. | — | 2011 | → |
| Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability. | Kutalik Z et al. | — | 2011 | → |
| Nucleotide discrimination with DNA immobilized in the MspA nanopore. | Manrao EA et al. | — | 2011 | → |
| Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation. | Wang K et al. | — | 2011 | → |
| Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. | Bennett SN et al. | — | 2011 | → |
| Polymorphism analysis of the CTLA-4 gene in paracoccidioidomycosis patients. | Lozano VF et al. | — | 2011 | → |
| Practical and theoretical considerations in study design for detecting gene-gene interactions using MDR and GMDR approaches. | Chen GB et al. | — | 2011 | → |
| Racial/ethnic variation in the association of lipid-related genetic variants with blood lipids in the US adult population. | Chang MH et al. | — | 2011 | → |
| Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. | Gilman SR et al. | — | 2011 | → |
| Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression. | Corrah TW et al. | — | 2011 | → |
| Recent progress in the study of the genetics of height. | Lettre G | — | 2011 | → |
| REMiner: a tool for unbiased mining and analysis of repetitive elements and their arrangement structures of large chromosomes. | Chung BI et al. | — | 2011 | → |
| Rethinking the genetic architecture of schizophrenia. | Mitchell KJ et al. | — | 2011 | → |
| Sequencing for the cream of the crop. | Chia JM et al. | — | 2011 | → |
| SNP-based pathway enrichment analysis for genome-wide association studies. | Weng L et al. | — | 2011 | → |
| SNPs and other features as they predispose to complex disease: genome-wide predictive analysis of a quantitative phenotype for hypertension. | Won JH et al. | — | 2011 | → |
| Sodium reabsorption in the thick ascending limb in relation to blood pressure: a clinical perspective. | Jung J et al. | — | 2011 | → |
| Statistical Analysis in Genetic Studies of Mental Illnesses. | Zhang H | — | 2011 | → |
| Successfully mapping novel asthma loci by GWAS. | Barnes KC | — | 2011 | → |
| Synopsis and meta-analysis of genetic association studies in osteoporosis for the focal adhesion family genes: the CUMAGAS-OSTEOporosis information system. | Zintzaras E et al. | — | 2011 | → |
| The conundrums of understanding genetic risks for autism spectrum disorders. | State MW et al. | — | 2011 | → |
| The emergence of human-evolutionary medical genomics. | Crespi BJ | — | 2011 | → |
| The genetics of common kidney disease: a pathway toward clinical relevance. | Drawz PE et al. | — | 2011 | → |
| The genetics of primary biliary cirrhosis: the revolution moves on. | Jones DE et al. | — | 2011 | → |
| The intermountain risk score predicts incremental age-specific long-term survival and life expectancy. | Horne BD et al. | — | 2011 | → |
| The PhenX Toolkit: get the most from your measures. | Hamilton CM et al. | — | 2011 | → |
| The population genetics of chronic kidney disease: insights from the MYH9-APOL1 locus. | Rosset S et al. | — | 2011 | → |
| The relative importance of common and rare genetic variants in the development of hypertriglyceridemia. | Evans D et al. | — | 2011 | → |
| Toward an understanding of hypertension resistance. | Subramanya AR et al. | — | 2011 | → |
| Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. | Kulminski AM et al. | — | 2011 | → |
| Type 1 diabetes: etiology, immunology, and therapeutic strategies. | van Belle TL et al. | — | 2011 | → |
| Uncover disease genes by maximizing information flow in the phenome-interactome network. | Chen Y et al. | — | 2011 | → |
| Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. | Culverhouse RC et al. | — | 2011 | → |
| Update in growth hormone therapy of children. | Collett-Solberg PF | — | 2011 | → |
| Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. | de Miguel-Yanes JM et al. | — | 2011 | → |
| 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. | Karayiorgou M et al. | — | 2010 | → |
| ABO blood group and other genetic variants associated with pancreatic cancer. | Lennon AM et al. | — | 2010 | → |
| A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain. | Feng Q et al. | — | 2010 | → |
| A compendium of genome-wide associations for cancer: critical synopsis and reappraisal. | Ioannidis JP et al. | — | 2010 | → |
| A conceptual framework for the developmental origins of health and disease. | Gluckman PD et al. | — | 2010 | → |
| Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies. | Lanzani C et al. | — | 2010 | → |
| Admixture mapping of end stage kidney disease genetic susceptibility using estimated mutual information ancestry informative markers. | Shlush LI et al. | — | 2010 | → |
| Advances in stroke 2009: update on the genetics of stroke and cerebrovascular disease 2009. | Hegele RA et al. | — | 2010 | → |
| A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. | Ratner E et al. | — | 2010 | → |
| Alzheimer's disease: diagnostics, prognostics and the road to prevention. | Grossman I et al. | — | 2010 | → |
| Ancestry and disease in the age of genomic medicine. | Rotimi CN et al. | — | 2010 | → |
| An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. | Patel CJ et al. | — | 2010 | → |
| An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population. | Kitsios GD et al. | — | 2010 | → |
| An update on the genetics of atopic dermatitis: scratching the surface in 2009. | Barnes KC | — | 2010 | → |
| A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility. | Tan IK et al. | — | 2010 | → |
| Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. | Lubitz SA et al. | — | 2010 | → |
| A statistical method for scanning the genome for regions with rare disease alleles. | Garner C | — | 2010 | → |
| ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci. | Turner SD et al. | — | 2010 | → |
| A tiny step closer to personalized risk prediction for breast cancer. | Devilee P et al. | — | 2010 | → |
| A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. | Roses AD et al. | — | 2010 | → |
| A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. | Xing C et al. | — | 2010 | → |
| Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer. | Galvan A et al. | — | 2010 | → |
| Biological, clinical and population relevance of 95 loci for blood lipids. | Teslovich TM et al. | — | 2010 | → |
| Biosocial Influences on the Family: A Decade Review. | D'Onofrio BM et al. | — | 2010 | → |
| Carbohydrate metabolic pathway genes associated with quantitative trait loci (QTL) for obesity and type 2 diabetes: identification by data mining. | Varma V et al. | — | 2010 | → |
| Challenges in the identification and use of rare disease-associated predisposition variants. | Carvajal-Carmona LG | — | 2010 | → |
| Colloquium papers: Numbering the hairs on our heads: the shared challenge and promise of phenomics. | Houle D | — | 2010 | → |
| Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations. | Johansson S et al. | — | 2010 | → |
| Comparing apples and oranges: equating the power of case-control and quantitative trait association studies. | Yang J et al. | — | 2010 | → |
| Complex genetic regulation of protein glycosylation. | Lauc G et al. | — | 2010 | → |
| Consilient research approaches in studying gene x environment interactions in alcohol research. | Sher KJ et al. | — | 2010 | → |
| Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups. | Waters KM et al. | — | 2010 | → |
| Coriell Personalized Medicine Collaborative<sup>®</sup>: a prospective study of the utility of personalized medicine. | Keller MA et al. | — | 2010 | → |
| Coronary heart disease risk prediction in the era of genome-wide association studies: current status and what the future holds. | Humphries SE et al. | — | 2010 | → |
| Credible genetic associations? | Munafò MR | — | 2010 | → |
| Current world literature. | — | — | 2010 | → |
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| Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures. | Salem RM et al. | — | 2010 | → |
| Deciphering genetic disease in the genomic era: the model of GnRH deficiency. | Sykiotis GP et al. | — | 2010 | → |
| Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. | Lachance J | — | 2010 | → |
| Disease genes and gene regulation by microRNAs. | Roberts R et al. | — | 2010 | → |
| DNA sequence variants and the practice of medicine. | Marian AJ | — | 2010 | → |
| DRD4 and DAT1 in ADHD: Functional neurobiology to pharmacogenetics. | Turic D et al. | — | 2010 | → |
| Epigenomics reveals a functional genome anatomy and a new approach to common disease. | Feinberg AP | — | 2010 | → |
| Estimating the total number of susceptibility variants underlying complex diseases from genome-wide association studies. | So HC et al. | — | 2010 | → |
| Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. | Park JH et al. | — | 2010 | → |
| Evolution in health and medicine Sackler colloquium: Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies. | Eyre-Walker A | — | 2010 | → |
| Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. | Feinberg AP et al. | — | 2010 | → |
| Exploring genetic susceptibility to cancer in diverse populations. | Haiman CA et al. | — | 2010 | → |
| Extending rare-variant testing strategies: analysis of noncoding sequence and imputed genotypes. | Zawistowski M et al. | — | 2010 | → |
| Gene-environment interactions in asthma and allergy: the end of the beginning? | Vercelli D | — | 2010 | → |
| General lessons from large-scale studies to identify human cancer predisposition genes. | Cazier JB et al. | — | 2010 | → |
| Genetic approaches to functional gastrointestinal disorders. | Saito YA et al. | — | 2010 | → |
| Genetic cardiovascular risk prediction: will we get there? | Thanassoulis G et al. | — | 2010 | → |
| Genetic causes of high and low serum HDL-cholesterol. | Weissglas-Volkov D et al. | — | 2010 | → |
| Genetic determinants of pubertal timing in the general population. | Gajdos ZK et al. | — | 2010 | → |
| Genetic epidemiology of chronic kidney disease. | Estrella MM et al. | — | 2010 | → |
| Genetic heterogeneity in human disease. | McClellan J et al. | — | 2010 | → |
| Genetic risk information for common diseases may indeed be already useful for prevention and early detection. | Gulcher J et al. | — | 2010 | → |
| Genetics and asthma disease susceptibility in the US Latino population. | Reibman J et al. | — | 2010 | → |
| Genetics and the kidney: promise, potential, and challenges. Introduction. | Sedor JR et al. | — | 2010 | → |
| Genetics of psychiatric disorders methods: molecular approaches. | Avramopoulos D | — | 2010 | → |
| Genetics of type 1 diabetes: what's next? | Pociot F et al. | — | 2010 | → |
| Genetic studies of common types of obesity: a critique of the current use of phenotypes. | Müller MJ et al. | — | 2010 | → |
| Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. | Kim JH et al. | — | 2010 | → |
| Genomewide association studies and assessment of risk of disease. | Rienhoff HY | — | 2010 | → |
| Genomewide association studies and assessment of risk of disease. | Pandey JP | — | 2010 | → |
| Genomewide association studies and assessment of the risk of disease. | Manolio TA | — | 2010 | → |
| Genome-wide association studies and beyond. | Witte JS | — | 2010 | → |
| Genome-wide association studies: a primer. | Corvin A et al. | — | 2010 | → |
| Genome-wide association studies for blood lipids. A great start but a long way to go. | Tai ES et al. | — | 2010 | → |
| Genomewide association studies in allergy and the influence of ethnicity. | Barnes KC | — | 2010 | → |
| Genome-wide association studies in diverse populations. | Rosenberg NA et al. | — | 2010 | → |
| Genome-wide association studies of cancer predisposition. | Stadler ZK et al. | — | 2010 | → |
| Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease? | Weidinger S et al. | — | 2010 | → |
| Genome-wide association studies: present status and future directions. | Cho JH | — | 2010 | → |
| Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity. | Beekman M et al. | — | 2010 | → |
| Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. | Kapur K et al. | — | 2010 | → |
| Genome-wide searching of rare genetic variants in WTCCC data. | Feng T et al. | — | 2010 | → |
| Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review. | Panagiotou OA et al. | — | 2010 | → |
| Genomics: Variations in blood lipids. | Shuldiner AR et al. | — | 2010 | → |
| Genotype-environment interaction and sociology: contributions and complexities. | Seabrook JA et al. | — | 2010 | → |
| Genotyping sleep disorders patients. | Kripke DF et al. | — | 2010 | → |
| Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. | Ober C et al. | — | 2010 | → |
| Grammatical evolution decision trees for detecting gene-gene interactions. | Motsinger-Reif AA et al. | — | 2010 | → |
| High-throughput discovery of rare insertions and deletions in large cohorts. | Vallania FL et al. | — | 2010 | → |
| Host genes associated with HIV/AIDS: advances in gene discovery. | An P et al. | — | 2010 | → |
| Human genome diversity: frequently asked questions. | Barbujani G et al. | — | 2010 | → |
| Hundreds of variants clustered in genomic loci and biological pathways affect human height. | Lango Allen H et al. | — | 2010 | → |
| Impact of Hardy-Weinberg equilibrium deviation on allele-based risk effect of genetic association studies and meta-analysis. | Zintzaras E | — | 2010 | → |
| Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes. | Grucza RA et al. | — | 2010 | → |
| Individualized medicine 2010. | Blum HE | — | 2010 | → |
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| Interleukin-28b: a key piece of the hepatitis C virus recovery puzzle. | Thio CL et al. | — | 2010 | → |
| Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. | Coassin S et al. | — | 2010 | → |
| ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. | Fellay J et al. | — | 2010 | → |
| Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease. | Anderson JL et al. | — | 2010 | → |
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| Past, present and future directions in human genetic susceptibility to tuberculosis. | Möller M et al. | — | 2010 | → |
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| Risk categorization for complex disorders according to genotype relative risk and precision in parameter estimates. | Goddard GH et al. | — | 2010 | → |
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| SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study. | Saccone SF et al. | — | 2010 | → |
| Study of transcriptional effects in Cis at the IFIH1 locus. | Zouk H et al. | — | 2010 | → |
| Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database. | Kitsios GD et al. | — | 2010 | → |
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| The genetics of child psychiatric disorders: focus on autism and Tourette syndrome. | State MW | — | 2010 | → |
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| The necessity of animal models in pain research. | Mogil JS et al. | — | 2010 | → |
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| The population genetics of mutations: good, bad and indifferent. | Loewe L et al. | — | 2010 | → |
| The prospect of genome-guided preventive medicine: a need and opportunity for genetic counselors. | O'Daniel JM | — | 2010 | → |
| The pursuit of genome-wide association studies: where are we now? | Ku CS et al. | — | 2010 | → |
| The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer. | Hawken SJ et al. | — | 2010 | → |
| Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. | Nicolae DL et al. | — | 2010 | → |
| Translating associations between common kidney diseases and genetic variation into the clinic. | Drawz PE et al. | — | 2010 | → |
| Uncovering the roles of rare variants in common disease through whole-genome sequencing. | Cirulli ET et al. | — | 2010 | → |
| What genes tell us about the pathogenesis of asthma and chronic obstructive pulmonary disease. | Weiss ST | — | 2010 | → |
| After the GWAS rush: nuggets of insight into the pathogenesis of autoimmune disease. | Danska JS et al. | — | 2009 | → |
| A functionalist perspective on social anxiety and avoidant personality disorder. | Lafreniere P | — | 2009 | → |
| A genome-wide genetic screen for host factors required for hepatitis C virus propagation. | Li Q et al. | — | 2009 | → |
| A genome-wide investigation of SNPs and CNVs in schizophrenia. | Need AC et al. | — | 2009 | → |
| A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. | Hegele RA et al. | — | 2009 | → |
| Are we getting anywhere in human pain genetics? | Mogil JS | — | 2009 | → |
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| Commentary: A new dawn for genetic epidemiology? | Frayling TM | — | 2009 | → |
| Control of fetal hemoglobin: new insights emerging from genomics and clinical implications. | Thein SL et al. | — | 2009 | → |
| Direct-to-consumer genetic testing: two sides of the coin. | Farkas DH et al. | — | 2009 | → |
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| Given the complexity of the human genome, can 'personalised medicine' or 'individualised drug therapy' ever be achieved? | Nebert DW | — | 2009 | → |
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| Impact of the next generation DNA sequencers. | Kato K | — | 2009 | → |
| Irrelevance of the chromosome 9p21.3 locus for acute cardiovascular events and restenosis. | Horne BD et al. | — | 2009 | → |
| KATP channel Kir6.2 E23K variant overrepresented in human heart failure is associated with impaired exercise stress response. | Reyes S et al. | — | 2009 | → |
| Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. | Walter C et al. | — | 2009 | → |
| Methods for optimizing statistical analyses in pharmacogenomics research. | Turner SD et al. | — | 2009 | → |
| Molecular networks as sensors and drivers of common human diseases. | Schadt EE | — | 2009 | → |
| Multistage analysis strategies for genome-wide association studies: summary of group 3 contributions to Genetic Analysis Workshop 16. | Neuman RJ et al. | — | 2009 | → |
| Nature's genetic gradients and the clinical phenotype. | Marian AJ | — | 2009 | → |
| Next-generation sequencing of cancer genomes: back to the future. | Walter MJ et al. | — | 2009 | → |
| Novel insights into the etiology of diabetes from genome-wide association studies. | Palmer CN | — | 2009 | → |
| Personalized medicine: individualized care of cancer patients. | Ely S | — | 2009 | → |
| Planning for translational research in genomics. | Hawkins N et al. | — | 2009 | → |
| Predicting response to short-acting bronchodilator medication using Bayesian networks. | Himes BE et al. | — | 2009 | → |
| Predictive genetic testing for coronary artery disease. | Johansen CT et al. | — | 2009 | → |
| Reporting and evaluating genetic association studies. | Peters SP | — | 2009 | → |
| Research 2.0: social networking and direct-to-consumer (DTC) genomics. | Lee SS et al. | — | 2009 | → |
| Sequence variants in three loci influence monocyte counts and erythrocyte volume. | Ferreira MA et al. | — | 2009 | → |
| Sequencing genomes: from individuals to populations. | Mir KU | — | 2009 | → |
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| The past and future of tuberculosis research. | Comas I et al. | — | 2009 | → |