Adverse childhood experiences, alcoholic parents, and later risk of alcoholism and depression.
paper
Cited
Public
Unavailable
- Authors
- Anda, Robert F; Whitfield, Charles L; Felitti, Vincent J; Chapman, Daniel; Edwards, Valerie J; Dube, Shanta R; Williamson, David F
- Year
- 2002
- Journal
- Psychiatric services (Washington, D.C.)
- PMID
- 12161676
- DOI
- 10.1176/appi.ps.53.8.1001
OBJECTIVE: The study examined how growing up with alcoholic parents and having adverse childhood experiences are related to the risk of alcoholism and depression in adulthood. METHODS: In this retrospective cohort study, 9,346 adults who visited a primary care clinic of a large health maintenance organization completed a survey about nine adverse childhood experiences: experiencing childhood emotional, physical, and sexual abuse; witnessing domestic violence; parental separation or divorce; and growing up with drug-abusing, mentally ill, suicidal, or criminal household members. The associations between parental alcohol abuse, the adverse experiences, and alcoholism and depression in adulthood were assessed by logistic regression analyses. RESULTS: The risk of having had all nine of the adverse childhood experiences was significantly greater among the 20 percent of respondents who reported parental alcohol abuse. The number of adverse experiences had a graded relationship to alcoholism and depression in adulthood, independent of parental alcohol abuse. The prevalence of alcoholism was higher among persons who reported parental alcohol abuse, no matter how many adverse experiences they reported. The association between parental alcohol abuse and depression was accounted for by the higher risk of having adverse childhood experiences in alcoholic families. CONCLUSIONS: Children in alcoholic households are more likely to have adverse experiences. The risk of alcoholism and depression in adulthood increases as the number of reported adverse experiences increases regardless of parental alcohol abuse. Depression among adult children of alcoholics appears to be largely, if not solely, due to the greater likelihood of having had adverse childhood experiences in a home with alcohol-abusing parents.
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|---|---|---|---|---|
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| Timing of mortality in mothers with recurrent convictions for driving under the influence of alcohol and their children, from childbirth to child age 17. | McCutcheon VV et al. | โ | 2021 | โ |
| Understanding factors associated with re-referral of youth for commercial sexual exploitation. | Kafafian M et al. | โ | 2021 | โ |
| Additional Insights into the Relationship Between Brain Network Architecture and Susceptibility and Resilience to the Psychiatric Sequelae of Childhood Maltreatment. | Teicher MH et al. | โ | 2020 | โ |
| Adult health burden and costs in California during 2013 associated with prior adverse childhood experiences. | Miller TR et al. | โ | 2020 | โ |
| Adverse Childhood Experiences and Internalizing Symptoms Among American Indian Adults with Type 2 Diabetes. | Elm JHL | โ | 2020 | โ |
| Adverse Childhood Experiences as Predictors of Perceived Health: Assessing the ACE Pyramid Model Using Multiple-Mediation. | Hughes P et al. | โ | 2020 | โ |
| Adverse Childhood Experiences: Implications for Offspring Telomere Length and Psychopathology. | Esteves KC et al. | โ | 2020 | โ |
| Adverse Childhood Experiences, Resilience, and Emotional Problems in Latinx Immigrant Youth. | Zetino YL et al. | โ | 2020 | โ |
| An overview of child maltreatment (neglect and abuse) associations with developmental trajectories and long-term outcomes in the 1958 British birth cohort. | Power C et al. | โ | 2020 | โ |
| Associations Among Childhood Household Dysfunction, Sexual Orientation, and DSM-5 Alcohol, Tobacco and Other Substance Use Disorders in Adulthood: Evidence From a National U.S. Survey. | McCabe SE et al. | โ | 2020 | โ |
| A Strategic Plan for Strengthening America's Families: A Brief from the Coalition of Behavioral Science Organizations. | Biglan A et al. | โ | 2020 | โ |
| A systematic review and meta-analysis examining the interrelationships between chemical and non-chemical stressors and inherent characteristics in children with ADHD. | Nilsen FM et al. | โ | 2020 | โ |
| Cause of parental death and child's health and education: The role of parental resources. | Kailaheimo-Lรถnnqvist S et al. | โ | 2020 | โ |
| Childhood familial environment and adulthood depression: evidence from a Chinese population-based study. | Zhou Q et al. | โ | 2020 | โ |
| Childhood maltreatment and problematic alcohol use in young adulthood: the roles of cognitive vulnerability to depression and depressive symptoms. | Shin SH et al. | โ | 2020 | โ |
| Child maltreatment and substance-use-related negative consequences: Longitudinal trajectories from early to mid adolescence. | Hagborg JM et al. | โ | 2020 | โ |
| Cumulative Exposure to Adverse Childhood Experience: Depressive Symptoms, Suicide Intensions and Suicide Plans among Senior High School Students in Nanchang City of China. | Jia Z et al. | โ | 2020 | โ |
| Determinants of new-onset alcohol use disorder in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. | Straus E et al. | โ | 2020 | โ |
| Disease burden of adverse childhood experiences across 14 states. | Waehrer GM et al. | โ | 2020 | โ |
| Do professionals ask about children when establishing a collaborative individual plan for clients? A cross-sectional study. | Elgรกn TH et al. | โ | 2020 | โ |
| Early-life stress is associated with a preponderance of habitual responding in a novel instrumental avoidance learning paradigm. | Gordon A et al. | โ | 2020 | โ |
| Entanglements of loneliness and mental ill health among young adult women. | Rรถnkรค AR et al. | โ | 2020 | โ |
| Evaluation of a Motivation-Based Intervention to Reduce Health Risk Behaviors among Black Primary Care Patients with Adverse Childhood Experiences. | Goldstein E et al. | โ | 2020 | โ |
| Evaluation of childhood traumatic experience as a risk factor for alcohol use disorder in adulthood. | Wang L et al. | โ | 2020 | โ |
| Exploring relationships as mediators of treatment outcomes among commercially sexually exploited youth. | Landers M et al. | โ | 2020 | โ |
| Family structure and alcohol use disorder: a register-based cohort study among offspring with and without parental alcohol use disorder. | Holst C et al. | โ | 2020 | โ |
| Females have more complex patterns of childhood adversity: implications for mental, social, and emotional outcomes in adulthood. | Haahr-Pedersen I et al. | โ | 2020 | โ |
| Harsh Parenting and Violence Against Children: A Trial with Ultrapoor Families in Francophone West Africa. | Ismayilova L et al. | โ | 2020 | โ |
| Longitudinal Impact of Life Events on Adolescent Binge Drinking in the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA). | Nooner KB et al. | โ | 2020 | โ |
| Sporting Activities for Individuals Who Experienced Trauma During Their Youth: A Meta-Study. | Massey WV et al. | โ | 2020 | โ |
| The influence of early familial adversity on adolescent risk behaviors and mental health: Stability and transition in family adversity profiles in a cohort sample. | Wadman R et al. | โ | 2020 | โ |
| The relationships between emerging adult transition themes, adverse childhood experiences, and substance use patterns among a community cohort of Hispanics. | Forster M et al. | โ | 2020 | โ |
| The Role of Adverse Childhood Experience on Depression Symptom, Prevalence, and Severity among School Going Adolescents. | Tsehay M et al. | โ | 2020 | โ |
| Trauma Exposure and Post-Traumatic Stress Disorder Among Youth in a High-Risk Family Study: Associations with Maternal and Paternal Alcohol Use Disorder. | Bender AK et al. | โ | 2020 | โ |
| Use of the Whole Child Assessment to identify children at risk of poor outcomes. | Marie-Mitchell A et al. | โ | 2020 | โ |
| A Biopsychosocial Overview of the Opioid Crisis: Considering Nutrition and Gastrointestinal Health. | Wiss DA | โ | 2019 | โ |
| Access to a high resource environment protects against accelerated maturation following early life stress: A translational animal model of high, medium and low security settings. | Strzelewicz AR et al. | โ | 2019 | โ |
| Adolescent social isolation increases cocaine seeking in male and female mice. | Fosnocht AQ et al. | โ | 2019 | โ |
| Adverse childhood events and risk of diabetes onset in the 1979 National longitudinal survey of youth cohort. | Lown EA et al. | โ | 2019 | โ |
| Adverse childhood experiences (ACEs) are associated with forced and very early sexual initiation among Black women accessing publicly funded STD clinics in Baltimore, MD. | Tsuyuki K et al. | โ | 2019 | โ |
| Adverse childhood experiences and mental health: Comparing the link in rural and urban men who have sex with men. | Giano Z et al. | โ | 2019 | โ |
| Adverse childhood experiences and the onset of chronic disease in young adulthood. | Sonu S et al. | โ | 2019 | โ |
| Adverse Childhood Experiences, Ethnicity, and Substance Use among College Students: Findings from a Two-State Sample. | Forster M et al. | โ | 2019 | โ |
| Adverse childhood experiences, self-care, and compassion outcomes in mental health providers working with trauma. | La Mott J et al. | โ | 2019 | โ |
| Adverse childhood experiences to adult adversity trends among parents: Socioeconomic, health, and developmental implications. | Borja S et al. | โ | 2019 | โ |
| Alcohol's harms to others in Wales, United Kingdom: Nature, magnitude and associations with mental well-being. | Quigg Z et al. | โ | 2019 | โ |
| Alcohol Use by Youth. | Ryan SA et al. | โ | 2019 | โ |
| Altered Brain Function in Drug-Naรฏve Major Depressive Disorder Patients With Early-Life Maltreatment: A Resting-State fMRI Study. | Xu Z et al. | โ | 2019 | โ |
| Association of Constellations of Parental Risk With Children's Subsequent Anxiety and Depression: Findings From a HUNT Survey and Health Registry Study. | Lund IO et al. | โ | 2019 | โ |
| Associations of Adverse Childhood Experiences with Past-Year DSM-5 Psychiatric and Substance Use Disorders in Older Adults. | Rhee TG et al. | โ | 2019 | โ |
| Blunted stress reactivity reveals vulnerability to early life adversity in young adults with a family history of alcoholism. | Lovallo WR et al. | โ | 2019 | โ |
| Born this way? A review of neurobiological and environmental evidence for the etiology of psychopathy. | Frazier A et al. | โ | 2019 | โ |
| Childhood maltreatment and alcohol-related problems in young adulthood: The protective role of parental warmth. | Shin SH et al. | โ | 2019 | โ |
| Dimensionality of Early Adversity and Associated Behavioral and Emotional Symptoms: Data from a Sample of Japanese Institutionalized Children and Adolescents. | Zhang Y et al. | โ | 2019 | โ |
| Early-Life Adversity and Blunted Stress Reactivity as Predictors of Alcohol and Drug use in Persons With COMT (rs4680) Val158Met Genotypes. | Lovallo WR et al. | โ | 2019 | โ |
| Fathers' alcohol use and suicidal behaviour in offspring during youth and young adulthood. | Landberg J et al. | โ | 2019 | โ |
| Impact of Adverse Childhood Experiences on Alcohol Use in Emerging Adults in Montenegro and Romania. | Brajoviฤ M et al. | โ | 2019 | โ |
| Influence of childhood adversity, approach motivation traits, and depression on individual differences in brain activation during reward anticipation. | DelDonno SR et al. | โ | 2019 | โ |
| Linkage between teen mother's childhood adversity and externalizing behaviors in their children at age 11: Three aspects of parenting. | Yoon Y et al. | โ | 2019 | โ |
| Long-term effects of parental divorce on mental health - A meta-analysis. | Auersperg F et al. | โ | 2019 | โ |
| Machine Learning Analysis of the Relationships Between Gray Matter Volume and Childhood Trauma in a Transdiagnostic Community-Based Sample. | Clausen AN et al. | โ | 2019 | โ |
| Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity. | Swart PC et al. | โ | 2019 | โ |
| Mental health profile and its relation with parental alcohol use problems and/or the experience of abuse in a sample of Moroccan high school students: an explorative study. | Zouini B et al. | โ | 2019 | โ |
| Parental alcohol use disorder with and without other mental disorders and offspring alcohol use disorder. | Holst C et al. | โ | 2019 | โ |
| Pathways connecting socioeconomic variables, substance abuse and gambling behaviour: a cross-sectional study on a sample of Italian high-school students. | Buja A et al. | โ | 2019 | โ |
| Race/Ethnicity Does Not Moderate the Relationship Between Adverse Life Experiences and Temporal Summation of the Nociceptive Flexion Reflex and Pain: Results From the Oklahoma Study of Native American Pain Risk. | Sturycz CA et al. | โ | 2019 | โ |
| Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity. | Kentner AC et al. | โ | 2019 | โ |
| "..that warm feeling that [alcohol] gave me was what I interpreted love would feel like.." Lived experience of excessive alcohol use and care proceedings by mothers in the family justice system in the UK. | Boreham M et al. | โ | 2019 | โ |
| The association between adverse childhood experiences and adult traumatic brain injury/concussion: a scoping review. | Ma Z et al. | โ | 2019 | โ |
| The impact of childhood trauma and psychophysiological reactivity on at-risk women's adjustment to parenthood. | Oosterman M et al. | โ | 2019 | โ |
| The role of adverse childhood experiences and mental health care use in psychological dysfunction of male multi-problem young adults. | van Duin L et al. | โ | 2019 | โ |
| Timing of Family Adversity During Adolescence and its Impact on Alcohol and Tobacco Initiation: A Longitudinal Study Among Taiwanese Adolescents. | Hsu YT et al. | โ | 2019 | โ |
| Tobacco and cannabis use in college students are predicted by sex-dimorphic interactions between MAOA genotype and child abuse. | Fite PJ et al. | โ | 2019 | โ |
| A Cross-Sectional Study of Early Childhood Educators' Childhood and Current Food Insecurity and Dietary Intake. | Swindle TM et al. | โ | 2018 | โ |
| Adolescent Victimization and Early-Adult Psychopathology: Approaching Causal Inference Using a Longitudinal Twin Study to Rule Out Noncausal Explanations. | Schaefer JD et al. | โ | 2018 | โ |
| Adverse childhood experiences among patients with substance use disorders at a referral psychiatric hospital in Kenya. | Kiburi SK et al. | โ | 2018 | โ |
| Adverse childhood experiences and access and utilization of health care. | Alcalรก HE et al. | โ | 2018 | โ |
| Adverse Childhood Experiences and Higher-Level Functional Limitations Among Older Japanese People: Results From the JAGES Study. | Amemiya A et al. | โ | 2018 | โ |
| Adverse Childhood Experiences and the Consequences on Neurobiological, Psychosocial, and Somatic Conditions Across the Lifespan. | Herzog JI et al. | โ | 2018 | โ |
| Adverse Childhood Experiences of Violent Female Offenders: A Comparison of Homicide and Sexual Perpetrators. | Pflugradt DM et al. | โ | 2018 | โ |
| An examination of sex differences on neurocognitive functioning and behavior problems in maltreated youth. | Nooner KB et al. | โ | 2018 | โ |
| Anhedonia in Trauma-Exposed Individuals: Functional Connectivity and Decision-Making Correlates. | Olson EA et al. | โ | 2018 | โ |
| Association of Childhood Adversity With Differential Susceptibility of Transdiagnostic Psychopathology to Environmental Stress in Adulthood. | Albott CS et al. | โ | 2018 | โ |
| Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. | McCutcheon VV et al. | โ | 2018 | โ |
| Childhood adversity as a transdiagnostic risk factor for affective disorders in adulthood: A systematic review focusing on biopsychosocial moderating and mediating variables. | Hoppen TH et al. | โ | 2018 | โ |
| Childhood Trauma and Two Stages of Alcohol Use in African American and European American Women: Findings from a Female Twin Sample. | Sartor CE et al. | โ | 2018 | โ |
| Combining online Community Reinforcement and Family Training (CRAFT) with a parent-training programme for parents with partners suffering from alcohol use disorder: study protocol for a randomised controlled trial. | Lindner P et al. | โ | 2018 | โ |
| Comparison of Characteristics of Female Drivers with Single and Multiple DUI Convictions. | Bender AK et al. | โ | 2018 | โ |
| Does Family History of Alcohol Use Disorder Relate to Differences in Regional Brain Volumes? A Descriptive Review with New Data. | McPhee MD et al. | โ | 2018 | โ |
| Early child adversity and psychopathology in adulthood: HPA axis and cognitive dysregulations as potential mechanisms. | Raymond C et al. | โ | 2018 | โ |
| Early life adversity potentiates expression of addiction-related traits. | Hynes TJ et al. | โ | 2018 | โ |
| Estimating mental health impacts of alcohol's harms from other drinkers: using propensity scoring methods with national cross-sectional data from the United States. | Karriker-Jaffe KJ et al. | โ | 2018 | โ |
| Examining protective and buffering associations between sociocultural factors and adverse childhood experiences among American Indian adults with type 2 diabetes: a quantitative, community-based participatory research approach. | Brockie TN et al. | โ | 2018 | โ |
| Fathers' Alcohol Consumption and Long-Term Risk for Mortality in Offspring. | Landberg J et al. | โ | 2018 | โ |
| Gender similarities in somatic depression and in DSM depression secondary symptom profiles within the context of severity and bereavement. | Thompson AH et al. | โ | 2018 | โ |
| Impact of adverse childhood experiences (ACEs) on adult alcohol consumption behaviors. | Loudermilk E et al. | โ | 2018 | โ |
| [Impact of Parents' Problem Drinking on Suicidal Ideation of Their University Student Children: The Multiple Mediating Effects of Childhood Trauma, Experiential Avoidance and Depression]. | Lee ES et al. | โ | 2018 | โ |
| Intergenerational Continuity in Depression: The Importance of Time-Varying Effects, Maternal Co-morbid Health Risk Behaviors and Child's Gender. | Augustyn MB et al. | โ | 2018 | โ |
| Life as she knows it: The effects of adverse childhood experiences on intimate partner violence among women prisoners. | Jones MS et al. | โ | 2018 | โ |
| Mentoring Program Enhancements Supporting Effective Mentoring of Children of Incarcerated Parents. | Stump KN et al. | โ | 2018 | โ |
| Negative voice-content as a full mediator of a relation between childhood adversity and distress ensuing from hearing voices. | Rosen C et al. | โ | 2018 | โ |
| Neural and psychological characteristics of college students with alcoholic parents differ depending on current alcohol use. | Brown-Rice KA et al. | โ | 2018 | โ |
| Patterns of adverse childhood experiences and substance use among young adults: A latent class analysis. | Shin SH et al. | โ | 2018 | โ |
| Profiles of adverse childhood experiences and impulsivity. | Shin SH et al. | โ | 2018 | โ |
| Psychiatric morbidity in children of alcoholic parents. | Mansharamani H et al. | โ | 2018 | โ |
| Relationship of Adverse Family Experiences to Resilience and School Engagement Among Vermont Youth. | Kasehagen L et al. | โ | 2018 | โ |
| Self-injury and suicide behavior among young people with perceived parental alcohol problems in Denmark: a school-based survey. | Pisinger VSC et al. | โ | 2018 | โ |
| The Effects of a Family Systems Intervention on Co-Occurring Internalizing and Externalizing Behaviors of Children with Substance Abusing Mothers: A Latent Transition Analysis. | Zhang J et al. | โ | 2018 | โ |
| The relationship between family-based adverse childhood experiences and substance use behaviors among a diverse sample of college students. | Forster M et al. | โ | 2018 | โ |
| Adverse childhood experience effects on opioid use initiation, injection drug use, and overdose among persons with opioid use disorder. | Stein MD et al. | โ | 2017 | โ |
| Adverse childhood experiences (ACEs) and later-life depression: perceived social support as a potential protective factor. | Cheong EV et al. | โ | 2017 | โ |
| Adverse Childhood Experiences and Cervical Cancer Screening. | Alcalรก HE et al. | โ | 2017 | โ |
| Adverse childhood experiences and life opportunities: Shifting the narrative. | Metzler M et al. | โ | 2017 | โ |
| Adverse Childhood Experiences and Substance Use History among Vulnerable Older Adults Living in Public Housing. | Larkin H et al. | โ | 2017 | โ |
| Adverse childhood experiences, mental health, and excessive alcohol use: Examination of race/ethnicity and sex differences. | Lee RD et al. | โ | 2017 | โ |
| Adverse Childhood Experiences Predict Alcohol Consumption Patterns Among Kenyan Mothers. | Goodman ML et al. | โ | 2017 | โ |
| An analysis of retrospective and repeat prospective reports of adverse childhood experiences from the South African Birth to Twenty Plus cohort. | Naicker SN et al. | โ | 2017 | โ |
| Association of adverse childhood experiences with lifetime mental and substance use disorders among men and women aged 50+ years. | Choi NG et al. | โ | 2017 | โ |
| Childhood maltreatment is associated with alteration in global network fiber-tract architecture independent of history of depression and anxiety. | Ohashi K et al. | โ | 2017 | โ |
| Cortical thickness and trait empathy in patients and people at high risk for alcohol use disorders. | Schmidt T et al. | โ | 2017 | โ |
| Does Employment-Related Resilience Affect the Relationship between Childhood Adversity, Community Violence, and Depression? | Welles SL et al. | โ | 2017 | โ |
| Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands. | McCutcheon VV et al. | โ | 2017 | โ |
| Going flat: examining heterogeneity in the soda-obesity relationship by subgroup and place of birth among Asian Americans. | Alcalรก HE et al. | โ | 2017 | โ |
| Impact of childhood adversities on depression in early adulthood: A longitudinal cohort study of 478,141 individuals in Sweden. | Bjรถrkenstam E et al. | โ | 2017 | โ |
| Maternal Adverse Childhood Experience and Infant Health: Biomedical and Psychosocial Risks as Intermediary Mechanisms. | Madigan S et al. | โ | 2017 | โ |
| Maternal alcohol use disorders and depression in emerging adulthood: Examining the relevance of social ties, childhood adversity, and socioeconomic status. | Wolfe JD | โ | 2017 | โ |
| Maternal Problem Drinking and Child Mental Health. | Husky MM et al. | โ | 2017 | โ |
| Partial mediator role of physical abuse on the relationship between attention-deficit/hyperactivity disorder symptoms and severity of dissociative experiences in a sample of inpatients with alcohol use disorder. | Evren C et al. | โ | 2017 | โ |
| Preadolescent sensation seeking and early adolescent stress relate to at-risk adolescents' substance use by age 15. | Charles NE et al. | โ | 2017 | โ |
| Spanking and adult mental health impairment: The case for the designation of spanking as an adverse childhood experience. | Afifi TO et al. | โ | 2017 | โ |
| Testing and testing positive: childhood adversities and later life HIV status among Kenyan women and their partners. | Goodman ML et al. | โ | 2017 | โ |
| The association between adverse childhood experiences and traumatic brain injury/concussion in adulthood: A scoping review protocol. | Ma Z et al. | โ | 2017 | โ |
| The impact of childhood maltreatment on the differential efficacy of CBASP versus escitalopram in patients with chronic depression: A secondary analysis. | Bausch P et al. | โ | 2017 | โ |
| The Relationship of Adverse Childhood Events to Smoking, Overweight, Obesity and Binge Drinking Among Women in Hawaii. | Remigio-Baker RA et al. | โ | 2017 | โ |
| Unpacking the impact of adverse childhood experiences on adult mental health. | Merrick MT et al. | โ | 2017 | โ |
| Adverse childhood experiences and association with health, mental health, and risky behavior in the kingdom of Saudi Arabia. | Almuneef M et al. | โ | 2016 | โ |
| A web-based group course intervention for 15-25-year-olds whose parents have substance use problems or mental illness: study protocol for a randomized controlled trial. | Elgรกn TH et al. | โ | 2016 | โ |
| Childhood Adversity and Adult Reports of Food Insecurity Among Households With Children. | Sun J et al. | โ | 2016 | โ |
| Childhood Household Dysfunction, Social Inequality and Alcohol Related Illness in Young Adulthood. A Swedish National Cohort Study. | Gauffin K et al. | โ | 2016 | โ |
| Child Poverty and the Promise of Human Capacity: Childhood as a Foundation for Healthy Aging. | Wise PH | โ | 2016 | โ |
| Drinking to ease the burden: a cross-sectional study on trauma, alcohol abuse and psychopathology in a post-conflict context. | Ertl V et al. | โ | 2016 | โ |
| Early Life Health, Trauma and Social Determinants of Lifetime Abstention from Alcohol. | Kerr WC et al. | โ | 2016 | โ |
| Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System. | Karkhanis AN et al. | โ | 2016 | โ |
| Families Affected by Parental Substance Use. | Smith VC et al. | โ | 2016 | โ |
| Flourishing after depression: Factors associated with achieving complete mental health among those with a history of depression. | Fuller-Thomson E et al. | โ | 2016 | โ |
| Influence of interactions between genes and childhood trauma on refractoriness in psychiatric disorders. | Kim JS et al. | โ | 2016 | โ |
| Mental disorders and harmful substance use in children of substance abusing parents: A longitudinal register-based study on a complete birth cohort born in 1991. | Jรครคskelรคinen M et al. | โ | 2016 | โ |
| Meta-analysis of the serotonin transporter promoter variant (5-HTTLPR) in relation to adverse environment and antisocial behavior. | Tielbeek JJ et al. | โ | 2016 | โ |
| Nedley Depression Hit Hypothesis: Identifying Depression and Its Causes. | Nedley N et al. | โ | 2016 | โ |
| Parental alcohol-related disorders and school performance in 16-year-olds-a Swedish national cohort study. | Berg L et al. | โ | 2016 | โ |
| Parental Substance Abuse As an Early Traumatic Event. Preliminary Findings on Neuropsychological and Personality Functioning in Young Drug Addicts Exposed to Drugs Early. | Parolin M et al. | โ | 2016 | โ |
| Perceived parental alcohol problems, internalizing problems and impaired parentโ-โchild relationships among 71โ988 young people in Denmark. | Pisinger VS et al. | โ | 2016 | โ |
| Post-traumatic stress disorder and alcohol misuse: comorbidity in UK military personnel. | Head M et al. | โ | 2016 | โ |
| Prevalence of children whose parents have a substance use disorder: Findings from a Swedish general population survey. | Raninen J et al. | โ | 2016 | โ |
| Profiles of Childhood Trauma in Patients with Alcohol Dependence and Their Associations with Addiction-Related Problems. | Lotzin A et al. | โ | 2016 | โ |
| Substance Abuse and Trauma. | Simmons S et al. | โ | 2016 | โ |
| The association of adverse childhood experiences with mid-life depressive symptoms and quality of life among incarcerated males: exploring multiple mediation. | Skarupski KA et al. | โ | 2016 | โ |
| The Impact of Specific and Complex Trauma on the Mental Health of Homeless Youth. | Wong CF et al. | โ | 2016 | โ |
| The Relative Contributions of Adverse Childhood Experiences and Healthy Environments to Child Flourishing in Delaware. | Thompson D et al. | โ | 2016 | โ |
| Vulnerable parenting among mothers with substance abuse in their family of origin: a cross-sectional comparative study of mothers in an infant and toddler program. | Tedgรฅrd E et al. | โ | 2016 | โ |
| Witnessing substance use increases same-day antisocial behavior among at-risk adolescents: Gene-environment interaction in a 30-day ecological momentary assessment study. | Russell MA et al. | โ | 2016 | โ |
| Addressing inequities in alcohol consumption and related harms. | Roche A et al. | โ | 2015 | โ |
| Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort. | Barboza Solรญs C et al. | โ | 2015 | โ |
| Adverse childhood experiences and substance use among Hispanic emerging adults in Southern California. | Allem JP et al. | โ | 2015 | โ |
| Adverse Childhood Experiences: Expanding the Concept of Adversity. | Cronholm PF et al. | โ | 2015 | โ |
| Associations between body mass index, post-traumatic stress disorder, and child maltreatment in young women. | Duncan AE et al. | โ | 2015 | โ |
| Beating the brain about abuse: Empirical and meta-analytic studies of the association between maltreatment and hippocampal volume across childhood and adolescence. | Riem MM et al. | โ | 2015 | โ |
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| Childhood adversity and behavioral health outcomes for youth: An investigation using state administrative data. | Lucenko BA et al. | โ | 2015 | โ |
| Childhood Maltreatment, Depression, and Suicidal Ideation: Critical Importance of Parental and Peer Emotional Abuse during Developmental Sensitive Periods in Males and Females. | Khan A et al. | โ | 2015 | โ |
| Childhood stress exposure among preadolescents with and without family histories of substance use disorders. | Charles NE et al. | โ | 2015 | โ |
| Childhood trauma levels in individuals attending adult mental health services: An evaluation of clinical records and structured measurement of childhood trauma. | Rossiter A et al. | โ | 2015 | โ |
| Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. | Karkhanis AN et al. | โ | 2015 | โ |
| Don't Step on the Tiger's Tail: A Mixed Methods Study of the Relationship Between Adult Impact of Childhood Adversity and Use of Coping Strategies. | Helitzer D et al. | โ | 2015 | โ |
| Effects of adverse childhood experiences on the association between intranasal oxytocin and social stress reactivity among individuals with cocaine dependence. | Flanagan JC et al. | โ | 2015 | โ |
| Family characteristics and health behaviour as antecedents of school nurses' concerns about adolescents' health and development: a path model approach. | Poutiainen H et al. | โ | 2015 | โ |
| Gender-specific profiles of adverse childhood experiences, past year mental and substance use disorders, and their associations among a national sample of adults in the United States. | Cavanaugh CE et al. | โ | 2015 | โ |
| Impact of residential schooling and of child abuse on substance use problem in Indigenous Peoples. | Ross A et al. | โ | 2015 | โ |
| Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation. | Charles NE et al. | โ | 2015 | โ |
| Lifetime prevalence of gender-based violence in US women: associations with mood/anxiety and substance use disorders. | Walsh K et al. | โ | 2015 | โ |
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| Polytraumatization in an adult national sample and its association with psychological distress and self-esteem. | Nilsson D et al. | โ | 2015 | โ |
| The impact of early life stress on risk of tobacco smoking initiation by adolescents. | Iakunchykova OP et al. | โ | 2015 | โ |
| The 'Maltreatment and Abuse Chronology of Exposure' (MACE) scale for the retrospective assessment of abuse and neglect during development. | Teicher MH et al. | โ | 2015 | โ |
| The Relationship of Adverse Childhood Experiences to PTSD, Depression, Poly-Drug Use and Suicide Attempt in Reservation-Based Native American Adolescents and Young Adults. | Brockie TN et al. | โ | 2015 | โ |
| The role of specific early trauma in adult depression: A meta-analysis of published literature. Childhood trauma and adult depression. | Mandelli L et al. | โ | 2015 | โ |
| The theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder. | McCrory EJ et al. | โ | 2015 | โ |
| "Wine you get every day, but a child you can't replace": The perceived impact of parental drinking on child outcomes in a South African township. | Choi KW et al. | โ | 2015 | โ |
| Alcohol misuse, alcohol-related risky behaviors, and childhood adversity among soldiers who returned from Iraq or Afghanistan. | Clarke-Walper K et al. | โ | 2014 | โ |
| Characteristics of women who consume alcohol before and after pregnancy recognition in a Canadian sample: a prospective cohort study. | McDonald SW et al. | โ | 2014 | โ |
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| Exercise prevents the increased anxiety-like behavior in lactational di-(2-ethylhexyl) phthalate-exposed female rats in late adolescence by improving the regulation of hypothalamus-pituitary-adrenal axis. | Wang DC et al. | โ | 2014 | โ |
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| Parental psychopathology moderates the influence of parental divorce on lifetime alcohol use disorders among Israeli adults. | Thompson RG et al. | โ | 2014 | โ |
| Remission from Depression among Adults with Arthritis: A 12-Year Followup of a Population-Based Study. | Fuller-Thomson E et al. | โ | 2014 | โ |
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| A Framework to Examine the Role of Epigenetics in Health Disparities among Native Americans. | Brockie TN et al. | โ | 2013 | โ |
| A preliminary study of psychiatric, familial, and medical characteristics of high-utilizing sickle cell disease patients. | Carroll PC et al. | โ | 2013 | โ |
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| Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes. | Teicher MH et al. | โ | 2013 | โ |
| Childhood trauma, personality disorders symptoms and current major depressive disorder in Togo. | Kounou KB et al. | โ | 2013 | โ |
| Circumstances and efforts: how important is their correlation for the measurement of inequality of opportunity in health? | Jusot F et al. | โ | 2013 | โ |
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| Parental Divorce, Maternal-Paternal Alcohol Problems, and Adult Offspring Lifetime Alcohol Dependence. | Thompson RG et al. | โ | 2013 | โ |
| Poly-victimization among juvenile justice-involved youths. | Ford JD et al. | โ | 2013 | โ |
| Prevalence of adolescents who perceive their parents to have alcohol problems: a Swedish national survey using a web panel. | Elgรกn TH et al. | โ | 2013 | โ |
| Psychometrics properties of early trauma inventory self report - short form (ETISR-SR) for the Brazilian context. | Osรณrio FL et al. | โ | 2013 | โ |
| Relationship among adverse childhood experiences, history of active military service, and adult outcomes: homelessness, mental health, and physical health. | Montgomery AE et al. | โ | 2013 | โ |
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| The effect of childhood socioeconomic position on alcohol-related disorders later in life: a Swedish national cohort study. | Gauffin K et al. | โ | 2013 | โ |
| The embodiment of adverse childhood experiences and cancer development: potential biological mechanisms and pathways across the life course. | Kelly-Irving M et al. | โ | 2013 | โ |
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| Design of a Web-based individual coping and alcohol-intervention program (web-ICAIP) for children of parents with alcohol problems: study protocol for a randomized controlled trial. | Elgรกn TH et al. | โ | 2012 | โ |
| Investigating the association between childhood sexual abuse and alcohol use disorders in women: does it matter how we ask about sexual abuse? | Sartor CE et al. | โ | 2012 | โ |
| Is high-risk use of intoxicants more common among adolescents who have seen their parents intoxicated? | Haugland SH et al. | โ | 2012 | โ |
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| Supporting the need for an integrated system of care for youth with co-occurring traumatic stress and substance abuse problems. | Suarez LM et al. | โ | 2012 | โ |
| The influence of gene-environment interactions on the development of alcoholism and drug dependence. | Enoch MA | โ | 2012 | โ |
| Adverse childhood experiences and cigarette smoking: the 2009 Arkansas and Louisiana Behavioral Risk Factor Surveillance Systems. | Vander Weg MW | โ | 2011 | โ |
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| Childhood physical punishment and the onset of drinking problems: evidence from metropolitan China. | Cheng HG et al. | โ | 2011 | โ |
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| Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. | Brenhouse HC et al. | โ | 2011 | โ |
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| Letter from Russia: child abuse and alcohol misuse in a victim. | Jargin SV | โ | 2011 | โ |
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| Associations between childhood intelligence (IQ), adult morbidity and mortality. | Kilgour AH et al. | โ | 2010 | โ |
| Cerebellar lingula size and experiential risk factors associated with high levels of alcohol and drug use in young adults. | Anderson CM et al. | โ | 2010 | โ |
| Childhood trauma in substance use disorder and depression: an analysis by gender among a Brazilian clinical sample. | Tucci AM et al. | โ | 2010 | โ |
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| Harsh physical punishment as a specific childhood adversity linked to adult drinking consequences: evidence from China. | Cheng HG et al. | โ | 2010 | โ |
| Patterns of functional impairment and their change among youth served in systems of care: an application of latent transition analysis. | Stephens RL et al. | โ | 2010 | โ |
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| Predictors of mental health, subjective burden, and rewards in family caregivers of patients with chronic liver disease. | Bolden L et al. | โ | 2010 | โ |
| Randomized controlled trial of a cognitive-behavioral therapy for at-risk Korean male adolescents. | Hyun MS et al. | โ | 2010 | โ |
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| Detrimental psychophysiological effects of early maternal deprivation in adolescent and adult rodents: altered responses to cannabinoid exposure. | Marco EM et al. | โ | 2009 | โ |
| Estimating the number of children exposed to parental psychiatric disorders through a national health survey. | Bassani DG et al. | โ | 2009 | โ |
| New estimates of the number of children living with substance misusing parents: results from UK national household surveys. | Manning V et al. | โ | 2009 | โ |
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| Problem Drinking, Unemployment, and Intimate Partner Violence among a Sample of Construction Industry Workers and their Partners. | Cunradi CB et al. | โ | 2009 | โ |
| Relationship between Multiple Forms of Maltreatment by a Parent or Guardian and Adolescent Alcohol Use. | Shin SH et al. | โ | 2009 | โ |
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| The differences in drinking patterns between Finnish-speaking majority and Swedish-speaking minority in Finland. | Paljรคrvi T et al. | โ | 2009 | โ |
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| Adrenocorticotropic hormone and cortisol plasma levels directly correlate with childhood neglect and depression measures in addicted patients. | Gerra G et al. | โ | 2008 | โ |
| Adverse childhood experiences and chronic obstructive pulmonary disease in adults. | Anda RF et al. | โ | 2008 | โ |
| Adverse childhood experiences and prescription drug use in a cohort study of adult HMO patients. | Anda RF et al. | โ | 2008 | โ |
| Breaking the cycle/mending the hoop: adverse childhood experiences among incarcerated American Indian/Alaska Native women in New Mexico. | De Ravello L et al. | โ | 2008 | โ |
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| The experience of abuse and mental health in the young Thai population A preliminary survey. | Jirapramukpitak T et al. | โ | 2005 | โ |
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| Exploring the relationship between alcohol use, childhood maltreatment, and treatment needs among female prisoners. | Mullings JL et al. | โ | 2004 | โ |
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| Perceived work stress and major depressive episodes in a population of employed Canadians over 18 years old. | Wang J | โ | 2004 | โ |
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