Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix.
- Authors
- Li, J; Ji, L
- Year
- 2005
- Journal
- Heredity
- PMID
- 16077740
- DOI
- 10.1038/sj.hdy.6800717
Correlated multiple testing is widely performed in genetic research, particularly in multilocus analyses of complex diseases. Failure to control appropriately for the effect of multiple testing will either result in a flood of false-positive claims or in true hits being overlooked. Cheverud proposed the idea of adjusting correlated tests as if they were independent, according to an 'effective number' (M(eff)) of independent tests. However, our experience has indicated that Cheverud's estimate of the Meff is overly large and will lead to excessively conservative results. We propose a more accurate estimate of the M(eff), and design M(eff)-based procedures to control the experiment-wise significant level and the false discovery rate. In an evaluation, based on both real and simulated data, the M(eff)-based procedures were able to control the error rate accurately and consequently resulted in a power increase, especially in multilocus analyses. The results confirm that the M(eff) is a useful concept in the error-rate control of correlated tests. With its efficiency and accuracy, the M(eff) method provides an alternative to computationally intensive methods such as the permutation test.
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| A multi-environment framework to evaluate the adaptation of wheat (Triticum aestivum) to heat stress. | Telfer P et al. | β | 2022 | β |
| A multi-omics study of circulating phospholipid markers of blood pressure. | Liu J et al. | β | 2022 | β |
| Analysis of a Multi-Environment Trial for Black Raspberry (<i>Rubus occidentalis</i> L.) Quality Traits. | Willman MR et al. | β | 2022 | β |
| Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses. | Ibi D et al. | β | 2022 | β |
| Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease. | Domingo-Relloso A et al. | β | 2022 | β |
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| Associations Between Traumatic Stress, Brain Volumes and Post-traumatic Stress Disorder Symptoms in Children: Data from the ABCD Study. | Bustamante D et al. | β | 2022 | β |
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| Characterizing Creative Thinking and Creative Achievements in Relation to Symptoms of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder. | Stolte M et al. | β | 2022 | β |
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| FreeSurfer-based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other collaborative efforts. | SΓ€mann PG et al. | β | 2022 | β |
| Genes of the Glutamatergic System and Tardive Dyskinesia in Patients with Schizophrenia. | Fedorenko OY et al. | β | 2022 | β |
| Genetic Analyses of Enamel Hypoplasia in Multiethnic Cohorts. | Alotaibi RN et al. | β | 2022 | β |
| Genetic evidence for facial variation being a composite phenotype of cranial variation and facial soft tissue thickness. | Qian W et al. | β | 2022 | β |
| Genome-wide association analysis of sucrose and alanine contents in edamame beans. | Wang Z et al. | β | 2022 | β |
| Genome-Wide Association Study and Genomic Selection for Proteinogenic Methionine in Soybean Seeds. | Singer WM et al. | β | 2022 | β |
| Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes. | Le Grand Q et al. | β | 2022 | β |
| Gut microbiome associations with host genotype vary across ethnicities and potentially influence cardiometabolic traits. | Boulund U et al. | β | 2022 | β |
| Habitual Intake of Marine-Derived n-3 PUFAs is Inversely Associated with a Cardiometabolic Inflammatory Profile in Yup'ik Alaska Native People. | Boyer BB et al. | β | 2022 | β |
| HCLC-FC: A novel statistical method for phenome-wide association studies. | Liang X et al. | β | 2022 | β |
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| Improved two-step testing of genome-wide gene-environment interactions | Kawaguchi ES et al. | β | 2022 | β |
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| Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice. | Doms S et al. | β | 2022 | β |
| Limb development genes underlie variation in human fingerprint patterns. | Li J et al. | β | 2022 | β |
| Metabolomic profiling in dogs with dilated cardiomyopathy eating non-traditional or traditional diets and in healthy controls. | Smith CE et al. | β | 2022 | β |
| Natural genetic variation as a tool for discovery in Caenorhabditis nematodes. | Andersen EC et al. | β | 2022 | β |
| Optimal population size to detect quantitative trait loci in Korean native chicken: a simulation study. | Nwogwugwu CP et al. | β | 2022 | β |
| Persistence of Anxiety/Depression Symptoms in Early Adolescence: A Prospective Study of Daily Life Stress, Rumination, and Daytime Sleepiness in a Genetically Informative Cohort. | Hansell NK et al. | β | 2022 | β |
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| Rice <i>Chalky Grain 5</i> regulates natural variation for grain quality under heat stress. | Chandran AKN et al. | β | 2022 | β |
| Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume. | de Zwarte SMC et al. | β | 2022 | β |
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| Sex Differences in the Metabolome of Alzheimer's Disease Progression. | Zarzar TG et al. | β | 2022 | β |
| Testing for association with rare variants in the coding and non-coding genome: RAVA-FIRST, a new approach based on CADD deleteriousness score. | Bocher O et al. | β | 2022 | β |
| The impact of species-wide gene expression variation on Caenorhabditis elegans complex traits. | Zhang G et al. | β | 2022 | β |
| The relationship between the gut microbiome and the risk of respiratory infections among newborns. | Moroishi Y et al. | β | 2022 | β |
| Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study. | Wang H et al. | β | 2022 | β |
| 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. | Hoskens H et al. | β | 2021 | β |
| A cross-platform approach identifies genetic regulators of human metabolism and health. | Lotta LA et al. | β | 2021 | β |
| Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium. | Dennis EL et al. | β | 2021 | β |
| Analyses stratified by maternal age and recombination further characterize genes associated with maternal nondisjunction of chromosome 21. | Chernus JM et al. | β | 2021 | β |
| ANGPTL3 Variants Associate with Lower Levels of Irisin and C-Peptide in a Cohort of Arab Individuals. | Alanbaei M et al. | β | 2021 | β |
| Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke: Meta-analysis From 7 Prospective Cohorts. | Vojinovic D et al. | β | 2021 | β |
| Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity: A Microbiome-Wide Analysis From Population Studies. | Chen Z et al. | β | 2021 | β |
| Association of structural variation with cardiometabolic traits in Finns. | Chen L et al. | β | 2021 | β |
| Bimodal effects of sunlight on major depressive disorder. | Son J et al. | β | 2021 | β |
| Brain Correlates of Suicide Attempt in 18,925 Participants Across 18 International Cohorts. | Campos AI et al. | β | 2021 | β |
| Causal association of cognitive reserve on Alzheimer's disease with putative sex difference. | Wang H et al. | β | 2021 | β |
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| Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study. | Wang W et al. | β | 2021 | β |
| Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. | Graff M et al. | β | 2021 | β |
| Dissecting Source-Sink Relationship of Subtending Leaf for Yield and Fiber Quality Attributes in Upland Cotton (<i>Gossypium hirsutum</i> L.). | Mangi N et al. | β | 2021 | β |
| Effective Dimensionality: A Tutorial. | Del Giudice M | β | 2021 | β |
| Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder. | Valstad M et al. | β | 2021 | β |
| Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts. | Laaksonen J et al. | β | 2021 | β |
| Genetic Analyses of Common Infections in the Avon Longitudinal Study of Parents and Children Cohort. | Chong AHW et al. | β | 2021 | β |
| Genetic architecture of photosynthesis energy partitioning as revealed by a genome-wide association approach. | Quero G et al. | β | 2021 | β |
| Genetic Linkage and Physical Mapping for an Oyster Mushroom (<i>Pleurotus cornucopiae</i>) and Quantitative Trait Locus Analysis for Cap Color. | Zhang Y et al. | β | 2021 | β |
| Genetics of Germination and Seedling Traits under Drought Stress in a MAGIC Population of Maize. | Rida S et al. | β | 2021 | β |
| Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism. | Li-Gao R et al. | β | 2021 | β |
| Genetic susceptibility of opioid receptor genes polymorphism to drug addiction: A candidate-gene association study. | Al-Eitan LN et al. | β | 2021 | β |
| Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density. | Liu CT et al. | β | 2021 | β |
| Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. | Liu C et al. | β | 2021 | β |
| Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. | Lai D et al. | β | 2021 | β |
| Genome-wide association analysis uncovers the genetic architecture of tradeoff between flowering date and yield components in sesame. | Sabag I et al. | β | 2021 | β |
| Genome-wide association and whole exome sequencing studies reveal a novel candidate locus for restless legs syndrome. | Ergun U et al. | β | 2021 | β |
| Genome-wide association mapping and genomic prediction for adult stage sclerotinia stem rot resistance in Brassica napus (L) under field environments. | Roy J et al. | β | 2021 | β |
| Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. | RΓΌhlemann MC et al. | β | 2021 | β |
| Genome Wide Association Study of Beef Traits in Local Alpine Breed Reveals the Diversity of the Pathways Involved and the Role of Time Stratification. | Mancin E et al. | β | 2021 | β |
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| Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines. | Mei W et al. | β | 2021 | β |
| GWAS significance thresholds for deep phenotyping studies can depend upon minor allele frequencies and sample size. | Asif H et al. | β | 2021 | β |
| Hippocampal subfield imaging and fractional anisotropy show parallel changes in Alzheimer's disease tau progression using simultaneous tau-PET/MRI at 3T. | Carlson ML et al. | β | 2021 | β |
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| Identifying complex gene-gene interactions: a mixed kernel omnibus testing approach. | Liu Y et al. | β | 2021 | β |
| Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in <i>ANGPTL3</i>. | Blackburn NB et al. | β | 2021 | β |
| Immune Trait Shifts in Association With Tobacco Smoking: A Study in Healthy Women. | Piaggeschi G et al. | β | 2021 | β |
| Impact of low-frequency coding variants on human facial shape. | Liu D et al. | β | 2021 | β |
| Implementing eScreening for suicide prevention in VA post-9/11 transition programs using a stepped-wedge, mixed-method, hybrid type-II implementation trial: a study protocol. | Pittman JOE et al. | β | 2021 | β |
| <i>PRICKLE1</i> Γ <i>FOCAD</i> Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits. | Liu D et al. | β | 2021 | β |
| Longitudinal Metabolic Profiling of Maternal Obesity, Gestational Diabetes, and Hypertensive Pregnancy Disorders. | KivelΓ€ J et al. | β | 2021 | β |
| <i>O</i>- and <i>N</i>-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function. | Dotz V et al. | β | 2021 | β |
| Multiple-testing correction in metabolome-wide association studies. | Peluso A et al. | β | 2021 | β |
| Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies. | Shapland CY et al. | β | 2021 | β |
| Novel Sources of Pre-Harvest Sprouting Resistance for Japonica Rice Improvement. | Lee JS et al. | β | 2021 | β |
| Oral health and related risk indicators in north-central Appalachia differ by rurality. | Zhou Y et al. | β | 2021 | β |
| Periventricular and deep abnormal white matter differ in associations with cognitive performance at midlife. | Sanderson-Cimino M et al. | β | 2021 | β |
| Placental response to maternal SARS-CoV-2 infection. | Mourad M et al. | β | 2021 | β |
| Pre-emptive Breeding Against Karnal Bunt Infection in Common Wheat: Combining Genomic and Agronomic Information to Identify Suitable Parents. | Emebiri L et al. | β | 2021 | β |
| Prenatal Exposure to Bisphenols and Phthalates and Postpartum Depression: The Role of Neurosteroid Hormone Disruption. | Jacobson MH et al. | β | 2021 | β |
| QTL Γ environment interactions underlie ionome divergence in switchgrass. | Zhang L et al. | β | 2021 | β |
| Schizophrenia-associated gene dysbindin-1 and tardive dyskinesia. | Maes MS et al. | β | 2021 | β |
| Shared heritability of human face and brain shape. | Naqvi S et al. | β | 2021 | β |
| Single-layered organic photovoltaics with double cascading charge transport pathways: 18% efficiencies. | Zhang M et al. | β | 2021 | β |
| Structural equation modeling for unraveling the multivariate genomic architecture of milk proteins in dairy cattle. | Pegolo S et al. | β | 2021 | β |
| The developmental origins of genetic factors influencing language and literacy: Associations with early-childhood vocabulary. | Verhoef E et al. | β | 2021 | β |
| The early-life exposome and epigenetic age acceleration in children. | de Prado-Bert P et al. | β | 2021 | β |
| The effects of <i>Tbx15</i> and <i>Pax1</i> on facial and other physical morphology in mice. | Qian Y et al. | β | 2021 | β |
| The Intersection of the Genetic Architectures of Orofacial Clefts and Normal Facial Variation. | Indencleef K et al. | β | 2021 | β |
| The <i>WtmsDW</i> Locus on Wheat Chromosome 2B Controls Major Natural Variation for Floret Sterility Responses to Heat Stress at Booting Stage. | Erena MF et al. | β | 2021 | β |
| The Relation Between Adult Weight Gain, Adipocyte Volume, and the Metabolic Profile at Middle Age. | Verkouter I et al. | β | 2021 | β |
| Tissue-Resident-Memory CD8<sup>+</sup> T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes. | Peng T et al. | β | 2021 | β |
| Translating insights from the seed metabolome into improved prediction for lipid-composition traits in oat (Avena sativa L.). | Campbell MT et al. | β | 2021 | β |
| Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile. | Ibi D et al. | β | 2021 | β |
| Uncovering the shared lipidomic markers of subclinical osteoporosis-atherosclerosis comorbidity: The Young Finns Study. | Mishra BH et al. | β | 2021 | β |
| Understanding the Effectiveness of Genomic Prediction in Tetraploid Potato. | Wilson S et al. | β | 2021 | β |
| Unraveling Heat Tolerance in Upland Cotton (<i>Gossypium hirsutum</i> L.) Using Univariate and Multivariate Analysis. | Zafar MM et al. | β | 2021 | β |
| Urinary phthalate metabolites and alternatives and serum sex steroid hormones among pre- and postmenopausal women from NHANES, 2013-16. | Long SE et al. | β | 2021 | β |
| Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology. | Shadrin AA et al. | β | 2021 | β |
| White Matter Disruption in Pediatric Traumatic Brain Injury: Results From ENIGMA Pediatric Moderate to Severe Traumatic Brain Injury. | Dennis EL et al. | β | 2021 | β |
| Whole Genome Sequence Data From Captive Baboons Implicate <i>RBFOX1</i> in Epileptic Seizure Risk. | Kos MZ et al. | β | 2021 | β |
| A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease. | ProkiΔ I et al. | β | 2020 | β |
| A framework for gene mapping in wheat demonstrated using the Yr7 yellow rust resistance gene. | Gardiner LJ et al. | β | 2020 | β |
| A Hitchhiker's guide to the potato wart disease resistance galaxy. | Prodhomme C et al. | β | 2020 | β |
| Alteration of the gut microbiome in first-episode drug-naΓ―ve and chronic medicated schizophrenia correlate with regional brain volumes. | Ma X et al. | β | 2020 | β |
| An integrated linkage map of interspecific backcross 2 (BC<sub>2</sub>) populations reveals QTLs associated with fatty acid composition and vegetative parameters influencing compactness in oil palm. | Yaakub Z et al. | β | 2020 | β |
| A prediction-based test for multiple endpoints. | Montgomery RN et al. | β | 2020 | β |
| Association of IGF1 and VEGFA polymorphisms with diabetic retinopathy in Pakistani population. | Khan N et al. | β | 2020 | β |
| Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts. | Eveleens Maarse BC et al. | β | 2020 | β |
| Associations between systemic inflammation and somatic depressive symptoms: Findings from the Moli-sani study. | Gialluisi A et al. | β | 2020 | β |
| Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease subjects. | Turpin W et al. | β | 2020 | β |
| Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis. | Thibord F et al. | β | 2020 | β |
| Cereblon (<i>CRBN</i>) gene polymorphisms predict clinical response and progression-free survival in relapsed/refractory multiple myeloma patients treated with lenalidomide: a pharmacogenetic study from the IMMEnSE consortium. | Iskierka-JaΕΌdΕΌewska E et al. | β | 2020 | β |
| Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases. | Martin TC et al. | β | 2020 | β |
| Detecting fitness epistasis in recently admixed populations with genome-wide data. | Ni X et al. | β | 2020 | β |
| Dissecting the genetics of cold tolerance in a multiparental maize population. | Yi Q et al. | β | 2020 | β |
| Distribution of P1(D1) wart disease resistance in potato germplasm and GWAS identification of haplotype-specific SNP markers. | Prodhomme C et al. | β | 2020 | β |
| Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases. | Martin TC et al. | β | 2020 | β |
| Eagle: multi-locus association mapping on a genome-wide scale made routine. | George AW et al. | β | 2020 | β |
| Elucidating the Genetic Architecture of Fiber Quality in Hemp (<i>Cannabis sativa</i> L.) Using a Genome-Wide Association Study. | Petit J et al. | β | 2020 | β |
| Genetic and genomic analysis of the seed-filling process in maize based on a logistic model. | Yin S et al. | β | 2020 | β |
| Genetic Architecture of Flowering Time and Sex Determination in Hemp (<i>Cannabis sativa</i> L.): A Genome-Wide Association Study. | Petit J et al. | β | 2020 | β |
| Genetic controls of short- and long-term stomatal CO2 responses in Arabidopsis thaliana. | Johansson KSL et al. | β | 2020 | β |
| Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. | KlariΔ L et al. | β | 2020 | β |
| High-frequency metabolite profiling and the incidence of recurrent cardiac events in patients with post-acute coronary syndrome. | Vroegindewey MM et al. | β | 2020 | β |
| LesionQuant for Assessment of MRI in Multiple Sclerosis-A Promising Supplement to the Visual Scan Inspection. | Brune S et al. | β | 2020 | β |
| Lifestyle and biological factors influence the relationship between mental health and low-grade inflammation. | Gialluisi A et al. | β | 2020 | β |
| Longitudinal alteration of cortical thickness and volume in high-impact sports. | Mills BD et al. | β | 2020 | β |
| Mapping crown rust resistance at multiple time points in elite oat germplasm. | McNish IG et al. | β | 2020 | β |
| Mapping of quantitative trait loci for traits linked to fusarium head blight in barley. | Ogrodowicz P et al. | β | 2020 | β |
| Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity. | Bos MM et al. | β | 2020 | β |
| Natural variation in a glucuronosyltransferase modulates propionate sensitivity in a C. elegans propionic acidemia model. | Na H et al. | β | 2020 | β |
| Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases. | GonzΓ‘lez JR et al. | β | 2020 | β |
| Posttraumatic stress symptom persistence across 24Β years: association with brain structures. | Franz CE et al. | β | 2020 | β |
| Quantitative trait loci mapping of polyphenol metabolites in blackcurrant (Ribes nigrum L.). | Abreu IN et al. | β | 2020 | β |
| Serial CT analysis in idiopathic pulmonary fibrosis: comparison of visual features that determine patient outcome. | Jacob J et al. | β | 2020 | β |
| Sex-Specific Genetic Susceptibility to Adverse Neurodevelopmental Outcome in Offspring of Pregnancies at Risk of Early Preterm Delivery. | Varner MW et al. | β | 2020 | β |
| Structural equation modeling for investigating multi-trait genetic architecture of udder health in dairy cattle. | Pegolo S et al. | β | 2020 | β |
| The Associations of Common Genetic Susceptibility Variants with Breast Cancer in Jordanian Arabs: A Case-Control Study. | Al-Eitan LN et al. | β | 2020 | β |
| Two-stage genome-wide association study for the identification of causal variants underlying hoof disorders in cattle. | Suchocki T et al. | β | 2020 | β |
| Variance heterogeneity genome-wide mapping for cadmium in bread wheat reveals novel genomic loci and epistatic interactions. | Hussain W et al. | β | 2020 | β |
| Variation in mouse pelvic morphology maps to locations enriched in Sox9 Class II and Pitx1 regulatory features. | Roseman CC et al. | β | 2020 | β |
| Yield reduction historically associated with the Aegilops ventricosa 7D<sup>V</sup> introgression is genetically and physically distinct from the eyespot resistance gene Pch1. | Pasquariello M et al. | β | 2020 | β |
| A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. | Chernus JM et al. | β | 2019 | β |
| Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans. | Wang H et al. | β | 2019 | β |
| Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn's Disease. | Turpin W et al. | β | 2019 | β |
| Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups. | Pirim D et al. | β | 2019 | β |
| Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study. | Al-Eitan LN et al. | β | 2019 | β |
| Association between polygenic risk for tobacco or alcohol consumption and liability to licit and illicit substance use in young Australian adults. | Chang LH et al. | β | 2019 | β |
| Association Between Pulmonary Vessel-Related Structures and Cryptogenic Fibrosing Alveolitis Using Derived Computed Tomography Among Chinese Patients. | Li X et al. | β | 2019 | β |
| Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population. | Al-Eitan LN et al. | β | 2019 | β |
| Association Of GSTM1, GSTT1 And GSTP1 Polymorphisms With Breast Cancer Among Jordanian Women. | Al-Eitan LN et al. | β | 2019 | β |
| Associations Between Prediagnostic Concentrations of Circulating Sex Steroid Hormones and Esophageal/Gastric Cardia Adenocarcinoma Among Men. | Petrick JL et al. | β | 2019 | β |
| Associations of non-high-density lipoprotein cholesterol, triglycerides and the total cholesterol/HDL-c ratio with arterial stiffness independent of low-density lipoprotein cholesterol in a Chinese population. | Wen J et al. | β | 2019 | β |
| Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. | Liu M et al. | β | 2019 | β |
| Beyond not bad or just okay: social predictors of young adults' wellbeing and functioning (a TRAILS study). | Richards JS et al. | β | 2019 | β |
| Body mass trajectories and cortical thickness in middle-aged men: a 42-year longitudinal study starting in young adulthood. | Franz CE et al. | β | 2019 | β |
| Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples. | Hoogman M et al. | β | 2019 | β |
| Characterisation of barley resistance to rhynchosporium on chromosome 6HS. | Coulter M et al. | β | 2019 | β |
| Correction for multiple testing in candidate-gene methylation studies. | Zhou Z et al. | β | 2019 | β |
| Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language. | Verhoef E et al. | β | 2019 | β |
| Dissecting quantitative resistance to Xanthomonas campestris pv. campestris in leaves of Brassica oleracea by QTL analysis. | Iglesias-BernabΓ© L et al. | β | 2019 | β |
| EDAR, LYPLAL1, PRDM16, PAX3, DKK1, TNFSF12, CACNA2D3, and SUPT3H gene variants influence facial morphology in a Eurasian population. | Li Y et al. | β | 2019 | β |
| Exome sequences and multi-environment field trials elucidate the genetic basis of adaptation in barley. | Bustos-Korts D et al. | β | 2019 | β |
| Functional annotation and Bayesian fine-mapping reveals candidate genes for important agronomic traits in Holstein bulls. | Jiang J et al. | β | 2019 | β |
| Genetic architecture of tipburn resistance in lettuce. | Macias-GonzΓ‘lez M et al. | β | 2019 | β |
| Genetic association and differential expression of PITX2 with acute appendicitis. | Orlova E et al. | β | 2019 | β |
| Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case-control study. | Al-Eitan LN et al. | β | 2019 | β |
| Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia. | Zai CC et al. | β | 2019 | β |
| Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. | Gialluisi A et al. | β | 2019 | β |
| Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. | Lai D et al. | β | 2019 | β |
| Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. | Salem RM et al. | β | 2019 | β |
| Genome-wide Significance Thresholds for Admixture Mapping Studies. | Grinde KE et al. | β | 2019 | β |
| GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. | Couto Alves A et al. | β | 2019 | β |
| Harnessing Novel Diversity From Landraces to Improve an Elite Barley Variety. | Monteagudo A et al. | β | 2019 | β |
| Identification of Climate and Genetic Factors That Control Fat Content and Fatty Acid Composition of <i>Theobroma cacao</i> L. Beans. | Mustiga GM et al. | β | 2019 | β |
| Identification of genetic biomarkers for alloimmunization in sickle cell disease. | Meinderts SM et al. | β | 2019 | β |
| <i>FTO</i> Variant rs1421085 Associates With Increased Body Weight, Soft Lean Mass, and Total Body Water Through Interaction With Ghrelin and Apolipoproteins in Arab Population. | Hebbar P et al. | β | 2019 | β |
| Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia. | Colijn JM et al. | β | 2019 | β |
| Influence of young adult cognitive ability and additional education on later-life cognition. | Kremen WS et al. | β | 2019 | β |
| Interactive effect between ATPase-related genes and early-life tobacco smoke exposure on bronchial hyper-responsiveness detected in asthma-ascertained families. | Dizier MH et al. | β | 2019 | β |
| Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer. | Kachuri L et al. | β | 2019 | β |
| Mapping resistance to Phytophthora root rot identifies independent loci from cultivated (Cicer arietinum L.) and wild (Cicer echinospermum P.H. Davis) chickpea. | Amalraj A et al. | β | 2019 | β |
| Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile. | Blauw LL et al. | β | 2019 | β |
| Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease. | Surowiec I et al. | β | 2019 | β |
| Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. | van der Spek A et al. | β | 2019 | β |
| Mucosa-Associated Microbiota in Ileoanal Pouches May Contribute to Clinical Symptoms, Particularly Stool Frequency, Independent of Endoscopic Disease Activity. | Turpin W et al. | β | 2019 | β |
| Natural variation in <i>C. elegans</i> arsenic toxicity is explained by differences in branched chain amino acid metabolism. | Zdraljevic S et al. | β | 2019 | β |
| Neural reward processing in paediatric Tourette syndrome and/or attention-deficit/hyperactivity disorder. | Akkermans SEA et al. | β | 2019 | β |
| Novel genetic loci affecting facial shape variation in humans. | Xiong Z et al. | β | 2019 | β |
| NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. | Alliey-Rodriguez N et al. | β | 2019 | β |
| Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development. | Cullen H et al. | β | 2019 | β |
| QTL and candidate genes associated with leaf anion concentrations in response to phosphate supply in Arabidopsis thaliana. | El-Soda M et al. | β | 2019 | β |
| QTL Γ environment interactions underlie adaptive divergence in switchgrass across a large latitudinal gradient. | Lowry DB et al. | β | 2019 | β |
| Quick approximation of threshold values for genome-wide association studies. | Hao Z et al. | β | 2019 | β |
| Relationship between gut microbiota and circulating metabolites in population-based cohorts. | Vojinovic D et al. | β | 2019 | β |
| Selection and gene flow shape niche-associated variation in pheromone response. | Lee D et al. | β | 2019 | β |
| Synovial fluid monocyte/macrophage subsets and their correlation to patient-reported outcomes in osteoarthritic patients: a cohort study. | GΓ³mez-AristizΓ‘bal A et al. | β | 2019 | β |
| Temporal Patterns of 14 Blood Biomarker candidates of Cardiac Remodeling in Relation to Prognosis of Patients With Chronic Heart Failure-The Bio- SH i FT Study. | Bouwens E et al. | β | 2019 | β |
| The dynamical signature of anhedonia in major depressive disorder: positive emotion dynamics, reactivity, and recovery. | Heininga VE et al. | β | 2019 | β |
| Tracing the ancestry of modern bread wheats. | Pont C et al. | β | 2019 | β |
| Unravelling the Complex Genetics of Karnal Bunt (<i>Tilletia indica</i>) Resistance in Common Wheat (<i>Triticum aestivum</i>) by Genetic Linkage and Genome-Wide Association Analyses. | Emebiri L et al. | β | 2019 | β |
| Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s. | Logue MW et al. | β | 2019 | β |
| Utility of temporal profiles of new cardio-renal and pulmonary candidate biomarkers in chronic heart failure. | Brankovic M et al. | β | 2019 | β |
| Variability with Astroglial Glutamate Transport Genetics Is Associated with Increased Risk for Post-Traumatic Seizures. | Kumar RG et al. | β | 2019 | β |
| Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population. | Gialluisi A et al. | β | 2019 | β |
| A comprehensive analysis of SNCA-related genetic risk in sporadic parkinson disease. | PihlstrΓΈm L et al. | β | 2018 | β |
| Alcohol intake and brain white matter in middle aged men: Microscopic and macroscopic differences. | McEvoy LK et al. | β | 2018 | β |
| A locus on barley chromosome 5H affects adult plant resistance to powdery mildew. | Gupta S et al. | β | 2018 | β |
| An Integrated Systems Genetics and Omics Toolkit to Probe Gene Function. | Li H et al. | β | 2018 | β |
| Assessing Panic: Bridging the Gap Between Fundamental Mechanisms and Daily Life Experience. | Leibold NK et al. | β | 2018 | β |
| Association Mapping of Flowering and Height Traits in Germplasm Enhancement of Maize Doubled Haploid (GEM-DH) Lines. | Vanous A et al. | β | 2018 | β |
| Association of Cystathionine Ξ²-Synthase Gene Polymorphisms With Preeclampsia. | de LeΓ³n Bautista MP et al. | β | 2018 | β |
| Association study of BDNF and DRD3 genes with alcohol use disorder in Schizophrenia. | Zai CC et al. | β | 2018 | β |
| Association study of Disrupted-In-Schizophrenia-1 gene variants and tardive dyskinesia. | Lu JY et al. | β | 2018 | β |
| Beyond the one-way ANOVA for 'omics data. | Hassall KL et al. | β | 2018 | β |
| Brain functional and perfusional alterations in schizophrenia: an arterial spin labeling study. | Oliveira ΓAF et al. | β | 2018 | β |
| Cardiometabolic Biomarkers and Their Temporal Patterns Predict Poor Outcome in Chronic Heart Failure (Bio-SHiFT Study). | Brankovic M et al. | β | 2018 | β |
| Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations. | Barrios C et al. | β | 2018 | β |
| Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. | van der Lee SJ et al. | β | 2018 | β |
| Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation. | Brinster R et al. | β | 2018 | β |
| DNA methylation and sex-specific expression of FKBP5 as correlates of one-month bedtime cortisol levels in healthy individuals. | Lee RS et al. | β | 2018 | β |
| DNA methylation mediates the effect of maternal cognitive appraisal of a disaster in pregnancy on the child's C-peptide secretion in adolescence: Project Ice Storm. | Cao-Lei L et al. | β | 2018 | β |
| Gene-level associations in suicide attempter families show overrepresentation of synaptic genes and genes differentially expressed in brain development. | Sokolowski M et al. | β | 2018 | β |
| Genetical genomics of quality related traits in potato tubers using proteomics. | Acharjee A et al. | β | 2018 | β |
| Genetic associations with childhood brain growth, defined in two longitudinal cohorts. | Szekely E et al. | β | 2018 | β |
| Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. | Hanscombe KB et al. | β | 2018 | β |
| Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth. | Clark EAS et al. | β | 2018 | β |
| Genome-wide analysis of blood gene expression in migraine implicates immune-inflammatory pathways. | Gerring ZF et al. | β | 2018 | β |
| Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population. | Hebbar P et al. | β | 2018 | β |
| Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. | Vojinovic D et al. | β | 2018 | β |
| Genome-Wide Association Study Using Historical Breeding Populations Discovers Genomic Regions Involved in High-Quality Rice. | Quero G et al. | β | 2018 | β |
| Genome-wide mapping of global-to-local genetic effects on human facial shape. | Claes P et al. | β | 2018 | β |
| Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. | Cuellar Partida G et al. | β | 2018 | β |
| HisCoM-GGI: Hierarchical structural component analysis of gene-gene interactions. | Choi S et al. | β | 2018 | β |
| HLA and KIR Associations of Cervical Neoplasia. | Bao X et al. | β | 2018 | β |
| Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populations. | Wiener HW et al. | β | 2018 | β |
| Lingual Gyrus Surface Area Is Associated with Anxiety-Depression Severity in Young Adults: A Genetic Clustering Approach. | Couvy-Duchesne B et al. | β | 2018 | β |
| Lipidomics and Biomarker Discovery in Kidney Disease. | Afshinnia F et al. | β | 2018 | β |
| Metabolic profiling of intra- and extracranial carotid artery atherosclerosis. | Vojinovic D et al. | β | 2018 | β |
| Metabolomic markers of fatigue: Association between circulating metabolome and fatigue in women with chronic widespread pain. | Freidin MB et al. | β | 2018 | β |
| Mood and anxiety disorders in very preterm/very low-birth weight individuals from 6 to 26Β years. | Jaekel J et al. | β | 2018 | β |
| New susceptibility loci for cutaneous melanoma risk and progression revealed using a porcine model. | Bourneuf E et al. | β | 2018 | β |
| PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics. | Zheng J et al. | β | 2018 | β |
| Pleiotropic Contribution of <i>MECOM</i> and <i>AVPR1A</i> to Aggression and Subcortical Brain Volumes. | van Donkelaar MMJ et al. | β | 2018 | β |
| Positive metacognitions about alcohol mediate the relationship between <i>FKBP5</i> variability and problematic drinking in a sample of young women. | Dragan WΕ et al. | β | 2018 | β |
| Predicting Outcomes in Idiopathic Pulmonary Fibrosis Using Automated Computed Tomographic Analysis. | Jacob J et al. | β | 2018 | β |
| Pregnancy risk factors in relation to oppositional-defiant and conduct disorder symptoms in the Avon Longitudinal Study of Parents and Children. | Ruisch IH et al. | β | 2018 | β |
| Putamen functional connectivity during inhibitory control in smokers and non-smokers. | Akkermans SEA et al. | β | 2018 | β |
| Resistance to Multiple Temperate and Tropical Stem and Sheath Diseases of Rice. | Rosas JE et al. | β | 2018 | β |
| Risk factors for parental psychopathology: a study in families with children or adolescents with psychopathology. | Wesseldijk LW et al. | β | 2018 | β |
| Six NSCL/P Loci Show Associations With Normal-Range Craniofacial Variation. | Indencleef K et al. | β | 2018 | β |
| SNPs Associated With Testosterone Levels Influence Human Facial Morphology. | Roosenboom J et al. | β | 2018 | β |
| Spatially Dense 3D Facial Heritability and Modules of Co-heritability in a Father-Offspring Design. | Hoskens H et al. | β | 2018 | β |
| Value generalization in human avoidance learning. | Norbury A et al. | β | 2018 | β |
| Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness. | Vojinovic D et al. | β | 2018 | β |
| Accelerating permutation testing in voxel-wise analysis through subspace tracking: A new plugin for SnPM. | Gutierrez-Barragan F et al. | β | 2017 | β |
| Affected Anatomical Rich Club and Structural-Functional Coupling in Young Offspring of Schizophrenia and Bipolar Disorder Patients. | Collin G et al. | β | 2017 | β |
| A genetic association study of CSMD1 and CSMD2 with cognitive function. | Athanasiu L et al. | β | 2017 | β |
| A genome-wide association study of seed composition traits in wild soybean (Glycine soja). | Leamy LJ et al. | β | 2017 | β |
| A large population-based association study between HLA and KIR genotypes and measles vaccine antibody responses. | Ovsyannikova IG et al. | β | 2017 | β |
| A Larger Chocolate Chip-Development of a 15K <i>Theobroma cacao</i> L. SNP Array to Create High-Density Linkage Maps. | Livingstone D et al. | β | 2017 | β |
| Allelic variants of OsHKT1;1 underlie the divergence between indica and japonica subspecies of rice (Oryza sativa) for root sodium content. | Campbell MT et al. | β | 2017 | β |
| A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes. | Liu J et al. | β | 2017 | β |
| A Predictive Model for Time-to-Flowering in the Common Bean Based on QTL and Environmental Variables. | Bhakta MS et al. | β | 2017 | β |
| Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study. | Zheng JS et al. | β | 2017 | β |
| Association mapping for phenology and plant architecture in maize shows higher power for developmental traits compared with growth influenced traits. | Bouchet S et al. | β | 2017 | β |
| Association of genetic variation with blood pressure traits among East Africans. | Kayima J et al. | β | 2017 | β |
| Associations Between Genomic Variants in Alcohol Dehydrogenase Genes and Alcohol Symptomatology in American Indians and European Americans: Distinctions and Convergence. | Peng Q et al. | β | 2017 | β |
| Attention Deficit Hyperactivity Disorder Symptoms and Low Educational Achievement: Evidence Supporting A Causal Hypothesis. | de Zeeuw EL et al. | β | 2017 | β |
| Common variants associated with changes in levels of circulating free fatty acids after administration of glucose-insulin-potassium (GIK) therapy in the IMMEDIATE trial. | Ellis KL et al. | β | 2017 | β |
| Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study. | Schilling S et al. | β | 2017 | β |
| Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. | Ng MCY et al. | β | 2017 | β |
| Dissecting the Genetic Basis of Local Adaptation in Soybean. | Bandillo NB et al. | β | 2017 | β |
| Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes. | Song Y et al. | β | 2017 | β |
| Epigenetic modifying enzyme expression in asthmatic airway epithelial cells and fibroblasts. | Stefanowicz D et al. | β | 2017 | β |
| Epigenome-wide association study of asthma and wheeze in childhood and adolescence. | Arathimos R et al. | β | 2017 | β |
| Gene expression analysis in asthma using a targeted multiplex array. | Pascoe CD et al. | β | 2017 | β |
| Genetic Association of <i>MMP10</i>, <i>MMP14</i>, and <i>MMP16</i> with Dental Caries. | Lewis DD et al. | β | 2017 | β |
| Genetic control of plasticity of oil yield for combined abiotic stresses using a joint approach of crop modelling and genome-wide association. | Mangin B et al. | β | 2017 | β |
| Genetic risk for obesity predicts nucleus accumbens size and responsivity to real-world food cues. | Rapuano KM et al. | β | 2017 | β |
| Genetic risk variants for metabolic traits in Arab populations. | Hebbar P et al. | β | 2017 | β |
| Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes. | JΓ€ger S et al. | β | 2017 | β |
| Genetic Variation in the Vesicular Monoamine Transporter: Preliminary Associations With Cognitive Outcomes After Severe Traumatic Brain Injury. | Markos SM et al. | β | 2017 | β |
| Genome-wide Association Mapping of Qualitatively Inherited Traits in a Germplasm Collection. | Bandillo NB et al. | β | 2017 | β |
| Genome-wide association study of working memory brain activation. | Blokland GAM et al. | β | 2017 | β |
| Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain. | Livshits G et al. | β | 2017 | β |
| Genome-wide survey in African Americans demonstrates potential epistasis of fitness in the human genome. | Wang H et al. | β | 2017 | β |
| Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. | van Rooij FJA et al. | β | 2017 | β |
| <i>COL4A2</i> is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls. | RannikmΓ€e K et al. | β | 2017 | β |
| <i>CPT1A</i> Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders. | Skotte L et al. | β | 2017 | β |
| Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinaemia in antipsychotic drug-treated patients with schizophrenia. | Ivanova SA et al. | β | 2017 | β |
| <i>In Vitro</i> Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children. | Wagner PJ et al. | β | 2017 | β |
| Increased Power To Dissect Adaptive Traits in Global Sorghum Diversity Using a Nested Association Mapping Population. | Bouchet S et al. | β | 2017 | β |
| Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct. | Li SX et al. | β | 2017 | β |
| Joint Analysis of SNP-SNP-Environment Interactions for Chronic Dialysis by an Improved Branch and Bound Algorithm. | Yang CH et al. | β | 2017 | β |
| Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. | McKay JD et al. | β | 2017 | β |
| Letter to the Editor: Posttraumatic stress disorder has genetic overlap with cardiometabolic traits. | Sumner JA et al. | β | 2017 | β |
| Mapping and expression of genes associated with raspberry fruit ripening and softening. | Simpson CG et al. | β | 2017 | β |
| Mapping of quantitative trait loci for grain yield and its components in a US popular winter wheat TAM 111 using 90K SNPs. | Assanga SO et al. | β | 2017 | β |
| Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity. | Couto Alves A et al. | β | 2017 | β |
| Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study. | Liu J et al. | β | 2017 | β |
| No evidence of large genetic effects on steroid response in asthma patients. | Mosteller M et al. | β | 2017 | β |
| Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study. | Sippel LM et al. | β | 2017 | β |
| PAC1 receptor (<i>ADCYAP1R1</i>) genotype and problematic alcohol use in a sample of young women. | Dragan WΕ et al. | β | 2017 | β |
| Preliminary Evidence for an Association Between Variants of the Catechol-O-Methyltransferase (COMT) Gene and Premature Ejaculation. | Jern P et al. | β | 2017 | β |
| QTL mapping identifies a major locus for resistance in wheat to Sunn pest (Eurygaster integriceps) feeding at the vegetative growth stage. | Emebiri LC et al. | β | 2017 | β |
| QTLs for earliness and yield-forming traits in the LubuskiβΓβCamB barley RIL population under various water regimes. | Ogrodowicz P et al. | β | 2017 | β |
| Quantitative trait loci for plant height in MaresiβΓβCamB barley population and their associations with yield-related traits under different water regimes. | MikoΕajczak K et al. | β | 2017 | β |
| Quantitative trait loci for yield and grain plumpness relative to maturity in three populations of barley (Hordeum vulgare L.) grown in a low rain-fall environment. | Obsa BT et al. | β | 2017 | β |
| Reward and punishment learning in daily life: A replication study. | Heininga VE et al. | β | 2017 | β |
| Selection on a behaviour-related gene during the first stages of the biological invasion pathway. | Mueller JC et al. | β | 2017 | β |
| Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. | Stergiakouli E et al. | β | 2017 | β |
| Signal localization: a new approach in signal discovery. | Malov SV et al. | β | 2017 | β |
| Single-Nucleotide Polymorphisms in Vitamin D-Related Genes May Modify Vitamin D-Breast Cancer Associations. | O'Brien KM et al. | β | 2017 | β |
| Single nucleotide polymorphisms within MicroRNAs, MicroRNA targets, and MicroRNA biogenesis genes and their impact on colorectal cancer survival. | Mullany LE et al. | β | 2017 | β |
| Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. | Liang J et al. | β | 2017 | β |
| Statin Effects on Metabolic Profiles: Data From the PREVEND IT (Prevention of Renal and Vascular End-stage Disease Intervention Trial). | Kofink D et al. | β | 2017 | β |
| Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls. | Artigas MS et al. | β | 2017 | β |
| Testing differential susceptibility: Plasticity genes, the social environment, and their interplay in adolescent response inhibition. | Richards JS et al. | β | 2017 | β |
| The Analysis of Ethnic Mixtures. | Zhu X et al. | β | 2017 | β |
| The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birth. | Bustos ML et al. | β | 2017 | β |
| The eyespot resistance genes Pch1 and Pch2 of wheat are not homoeoloci. | Pasquariello M et al. | β | 2017 | β |
| The TCN2 variant of rs9606756 [Ile23Val] acts as risk loci for obesity-related traits and mediates by interacting with Apo-A1. | Hebbar P et al. | β | 2017 | β |
| TRPA1 gene polymorphisms and childhood asthma. | Gallo V et al. | β | 2017 | β |
| Validation and psychometric properties of the Somatic and Psychological HEalth REport (SPHERE) in a young Australian-based population sample using non-parametric item response theory. | Couvy-Duchesne B et al. | β | 2017 | β |
| Variants on chromosome 4q21 near PKD2 and SIBLINGs are associated with dental caries. | Eckert S et al. | β | 2017 | β |
| Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention. | Billings LK et al. | β | 2017 | β |
| Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial. | Barry EL et al. | β | 2017 | β |
| 1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. | Schedel M et al. | β | 2016 | β |
| A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants. | Vaysse A et al. | β | 2016 | β |
| Adolescent behavioral and neural reward sensitivity: a test of the differential susceptibility theory. | Richards JS et al. | β | 2016 | β |
| A GABBR2 gene variant modifies pathophysiology in Huntington's disease. | Philpott AL et al. | β | 2016 | β |
| An Efficient Multiple-Testing Adjustment for eQTL Studies that Accounts for Linkage Disequilibrium between Variants. | Davis JR et al. | β | 2016 | β |
| An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication. | Rijlaarsdam J et al. | β | 2016 | β |
| A QTL on the short arm of wheat (Triticum aestivum L.) chromosome 3B affects the stability of grain weight in plants exposed to a brief heat shock early in grain filling. | Shirdelmoghanloo H et al. | β | 2016 | β |
| Ascertainment bias from imputation methods evaluation in wheat. | Brandariz SP et al. | β | 2016 | β |
| Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. | Hampras SS et al. | β | 2016 | β |
| Association mapping for cold tolerance in two large maize inbred panels. | Revilla P et al. | β | 2016 | β |
| Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study. | Pei YF et al. | β | 2016 | β |
| Association of Epidemiologic Factors and Genetic Variants Influencing Hypothalamic-Pituitary-Adrenocortical Axis Function With Postconcussive Symptoms After Minor Motor Vehicle Collision. | Auvergne L et al. | β | 2016 | β |
| Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages. | Misra MK et al. | β | 2016 | β |
| Association of functional genetic variants of transcription factor Forkhead Box P3 and Nuclear Factor-ΞΊB with end-stage renal disease and renal allograft outcome. | Misra MK et al. | β | 2016 | β |
| Association of host genome with intestinal microbial composition in a large healthy cohort. | Turpin W et al. | β | 2016 | β |
| Association of orexin receptor polymorphisms with antipsychotic-induced weight gain. | Tiwari AK et al. | β | 2016 | β |
| Association of REL polymorphisms and outcome of patients with septic shock. | Toubiana J et al. | β | 2016 | β |
| Association of the IGF1 gene with fasting insulin levels. | Willems SM et al. | β | 2016 | β |
| Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. | Schwantes-An TH et al. | β | 2016 | β |
| Association study of MMP8 gene in osteoarthritis. | NΓ€kki A et al. | β | 2016 | β |
| Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain. | Zai CC et al. | β | 2016 | β |
| A study of genetic and environmental contributions to structural brain changes over time in twins concordant and discordant for bipolar disorder. | Bootsman F et al. | β | 2016 | β |
| Brain-Derived Neurotrophic Factor (Val66Met) and Serotonin Transporter (5-HTTLPR) Polymorphisms Modulate Plasticity in Inhibitory Control Performance Over Time but Independent of Inhibitory Control Training. | Enge S et al. | β | 2016 | β |
| Co-occurrence and symptomatology of fatigue and depression. | Corfield EC et al. | β | 2016 | β |
| Cortical chemoarchitecture shapes macroscale effective functional connectivity patterns in macaque cerebral cortex. | Turk E et al. | β | 2016 | β |
| Cross-Sectional Area of the Rotator Cuff Muscles in MRI - Is there Evidence for a Biomechanical Balanced Shoulder? | Bouaicha S et al. | β | 2016 | β |
| Developmentally Sensitive Interaction Effects of Genes and the Social Environment on Total and Subcortical Brain Volumes. | Richards JS et al. | β | 2016 | β |
| Diagnosing Depression in Chronic Pain Patients: DSM-IV Major Depressive Disorder vs. Beck Depression Inventory (BDI). | Knaster P et al. | β | 2016 | β |
| DNA methylation mediates the effect of exposure to prenatal maternal stress on cytokine production in children at age 13Β½β years: Project Ice Storm. | Cao-Lei L et al. | β | 2016 | β |
| DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis. | Sarnowski C et al. | β | 2016 | β |
| Early report on brain arousal regulation in manic vs depressive episodes in bipolar disorder. | Wittekind DA et al. | β | 2016 | β |
| Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity. | Deelen J et al. | β | 2016 | β |
| Energy homeostasis genes and survival after breast cancer diagnosis: the Breast Cancer Health Disparities Study. | Pellatt AJ et al. | β | 2016 | β |
| Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis. | Harrison RN et al. | β | 2016 | β |
| Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia. | de Jong S et al. | β | 2016 | β |
| Genetic analysis of developmental and adaptive traits in three doubled haploid populations of barley (Hordeum vulgare L.). | Obsa BT et al. | β | 2016 | β |
| Genetic diversity, linkage disequilibrium and power of a large grapevine (Vitis vinifera L) diversity panel newly designed for association studies. | Nicolas SD et al. | β | 2016 | β |
| Genetic variation in neuronal glutamate transport genes and associations with posttraumatic seizure. | Ritter AC et al. | β | 2016 | β |
| Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. | Shaffer JR et al. | β | 2016 | β |
| Heritability of cortical thickness changes over time in twin pairs discordant for schizophrenia. | Hedman AM et al. | β | 2016 | β |
| High Prevalence of Smoking in the Roma Population Seems to Have No Genetic Background. | Fiatal S et al. | β | 2016 | β |
| HLA Class I and II alleles, heterozygosity and HLA-KIR interactions are associated with rates of genital HSV shedding and lesions. | Magaret A et al. | β | 2016 | β |
| HvDep1 Is a Positive Regulator of Culm Elongation and Grain Size in Barley and Impacts Yield in an Environment-Dependent Manner. | Wendt T et al. | β | 2016 | β |
| Identification of environmentally stable QTL for resistance against Leptosphaeria maculans in oilseed rape (Brassica napus). | Huang YJ et al. | β | 2016 | β |
| Impact of polymorphisms in microRNA biogenesis genes on colon cancer risk and microRNA expression levels: a population-based, case-control study. | Mullany LE et al. | β | 2016 | β |
| Improvement of Predictive Ability by Uniform Coverage of the Target Genetic Space. | Bustos-Korts D et al. | β | 2016 | β |
| Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples. | Mastrokolias A et al. | β | 2016 | β |
| Investigation of gene-diet interactions in the incretin system and risk of type 2 diabetes: the EPIC-InterAct study. | InterAct Consortium | β | 2016 | β |
| Lack of Association between <i>SLC30A8</i> Variants and Type 2 Diabetes in Mexican American Families. | Kulkarni H et al. | β | 2016 | β |
| Lactation is associated with altered metabolomic signatures in women with gestational diabetes. | Much D et al. | β | 2016 | β |
| Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. | Aslibekyan S et al. | β | 2016 | β |
| Lower Sensitivity to Happy and Angry Facial Emotions in Young Adults with Psychiatric Problems. | Vrijen C et al. | β | 2016 | β |
| Low Temperature Affects Stem Cell Maintenance in Brassica oleracea Seedlings. | de Jonge J et al. | β | 2016 | β |
| Multi-trait QTL analysis for agronomic and quality characters of Agaricus bisporus (button mushrooms). | Gao W et al. | β | 2016 | β |
| Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. | Jaeger PA et al. | β | 2016 | β |
| Next Generation Mapping of Enological Traits in an F2 Interspecific Grapevine Hybrid Family. | Yang S et al. | β | 2016 | β |
| No Evidence of Causal Effects of Blood Pressure on Cognition in the Population at Large. | Swagerman SC et al. | β | 2016 | β |
| On the Accuracy of Genomic Selection. | Rabier CE et al. | β | 2016 | β |
| Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder. | Rucker JJ et al. | β | 2016 | β |
| Population structure and genome-wide association analysis for frost tolerance in oat using continuous SNP array signal intensity ratios. | Tumino G et al. | β | 2016 | β |
| Quantitative Trait Loci for Yield and Yield-Related Traits in Spring Barley Populations Derived from Crosses between European and Syrian Cultivars. | MikoΕajczak K et al. | β | 2016 | β |
| Role of MMP-2, MMP-7, MMP-9 and TIMP-2 in the development of recurrent depressive disorder. | BobiΕska K et al. | β | 2016 | β |
| Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder. | Czarny P et al. | β | 2016 | β |
| Targeted and Untargeted Approaches Unravel Novel Candidate Genes and Diagnostic SNPs for Quantitative Resistance of the Potato (Solanum tuberosum L.) to Phytophthora infestans Causing the Late Blight Disease. | Mosquera T et al. | β | 2016 | β |
| Testing for association in case-control genome-wide association studies with shared controls. | Chen Z et al. | β | 2016 | β |
| The Association Between Low Back Pain and Composition of IgG Glycome. | Freidin MB et al. | β | 2016 | β |
| The association of single nucleotide polymorphisms of the maternal cystathionine-Ξ²-synthase gene with early-onset preeclampsia. | Holwerda KM et al. | β | 2016 | β |
| The Use of Multiplicity Corrections, Order Statistics and Generalized Family-Wise Statistics with Application to Genome-Wide Studies. | Schrodi SJ | β | 2016 | β |
| Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep. | Jawinski P et al. | β | 2016 | β |
| Topology of genetic associations between regional gray matter volume and intellectual ability: Evidence for a high capacity network. | Bohlken MM et al. | β | 2016 | β |
| Tract-specific white matter microstructure and gait in humans. | Verlinden VJ et al. | β | 2016 | β |
| Trans-ethnic Meta-analysis and Functional Annotation Illuminates theΒ Genetic Architecture of Fasting Glucose and Insulin. | Liu CT et al. | β | 2016 | β |
| Transformation Invariant Control of Voxel-Wise False Discovery Rate. | Li J et al. | β | 2016 | β |
| VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls. | Tesli M et al. | β | 2016 | β |
| A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. | Belalcazar LM et al. | β | 2015 | β |
| Addressing population-specific multiple testing burdens in genetic association studies. | Sobota RS et al. | β | 2015 | β |
| An association between a dopamine transporter gene (SLC6A3) haplotype and ADHD symptom measures in nonclinical adults. | Tong JH et al. | β | 2015 | β |
| A Population Structure and Genome-Wide Association Analysis on the USDA Soybean Germplasm Collection. | Bandillo N et al. | β | 2015 | β |
| Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hispanic and non-Hispanic white women: The breast cancer health disparities study. | Connor AE et al. | β | 2015 | β |
| Associations of common variants in the BST2 region with HIV-1 acquisition in African American and European American people who inject drugs. | Hancock DB et al. | β | 2015 | β |
| Associations of lipid-related genetic markers with elevated carotid intima-media thickness in middle-age adults and elders. | Chen YC et al. | β | 2015 | β |
| Association study of GABAA Ξ±2 receptor subunit gene variants in antipsychotic-associated weight gain. | Zai CC et al. | β | 2015 | β |
| Back to Acid Soil Fields: The Citrate Transporter SbMATE Is a Major Asset for Sustainable Grain Yield for Sorghum Cultivated on Acid Soils. | Carvalho G et al. | β | 2015 | β |
| Brain size affects the behavioural response to predators in female guppies (Poecilia reticulata). | van der Bijl W et al. | β | 2015 | β |
| Changes in thickness and surface area of the human cortex and their relationship with intelligence. | Schnack HG et al. | β | 2015 | β |
| Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1. | Hancock DB et al. | β | 2015 | β |
| Cognitive heterogeneity in adult attention deficit/hyperactivity disorder: A systematic analysis of neuropsychological measurements. | Mostert JC et al. | β | 2015 | β |
| Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema. | Kaidonis G et al. | β | 2015 | β |
| Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. | RannikmΓ€e K et al. | β | 2015 | β |
| COMT gene locus: new functional variants. | Meloto CB et al. | β | 2015 | β |
| Controlling False Discovery Rate in Signal Space for Transformation-Invariant Thresholding of Statistical Maps. | Li J et al. | β | 2015 | β |
| Cytotoxic T-lymphocyte antigen 4 gene polymorphism influences the incidence of symptomatic human cytomegalovirus infection after renal transplantation. | Misra MK et al. | β | 2015 | β |
| Determinants of intestinal permeability in healthy first-degree relatives of individuals with Crohn's disease. | Kevans D et al. | β | 2015 | β |
| Differential susceptibility to maternal expressed emotion in children with ADHD and their siblings? Investigating plasticity genes, prosocial and antisocial behaviour. | Richards JS et al. | β | 2015 | β |
| Domain dependent associations between cognitive functioning and regular voluntary exercise behavior. | Swagerman SC et al. | β | 2015 | β |
| Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder. | Kimbrel NA et al. | β | 2015 | β |
| Endothelin-1 Pathway Polymorphisms and Outcomes in Pulmonary Arterial Hypertension. | Benza RL et al. | β | 2015 | β |
| Energy homeostasis genes and breast cancer risk: The influence of ancestry, body size, and menopausal status, the breast cancer health disparities study. | Slattery ML et al. | β | 2015 | β |
| Exploring effective multiplicity in multichannel functional near-infrared spectroscopy using eigenvalues of correlation matrices. | Uga M et al. | β | 2015 | β |
| False discovery rates for rare variants from sequenced data. | Capanu M et al. | β | 2015 | β |
| Fine mapping the <i>CETP</i> region reveals a common intronic insertion associated to HDL-C. | van Leeuwen EM et al. | β | 2015 | β |
| Genetic architecture of maize kernel row number and whole genome prediction. | Liu L et al. | β | 2015 | β |
| Genetic modifiers of response to glucose-insulin-potassium (GIK) infusion in acute coronary syndromes and associations with clinical outcomes in the IMMEDIATE trial. | Ellis KL et al. | β | 2015 | β |
| Genetic Predictors of Depressive Symptoms in the Look AHEAD Trial. | McCaffery JM et al. | β | 2015 | β |
| Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials. | Papandonatos GD et al. | β | 2015 | β |
| Genetics of complex traits in psychiatry. | Gelernter J | β | 2015 | β |
| Genetic variation at glucose and insulin trait loci and response to glucose-insulin-potassium (GIK) therapy: the IMMEDIATE trial. | Ellis KL et al. | β | 2015 | β |
| Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development. | Diamond ML et al. | β | 2015 | β |
| Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. | Draisma HHM et al. | β | 2015 | β |
| Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. | Gelernter J et al. | β | 2015 | β |
| Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet. | Pasricha S et al. | β | 2015 | β |
| Implication of HLA-G 5' upstream regulatory region polymorphisms in idiopathic recurrent spontaneous abortions. | Agrawal D et al. | β | 2015 | β |
| Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk. | Brossard M et al. | β | 2015 | β |
| Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders. | Zai CC et al. | β | 2015 | β |
| Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. | Vaughan LK et al. | β | 2015 | β |
| MAPK genes interact with diet and lifestyle factors to alter risk of breast cancer: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2015 | β |
| Mapping a Type 1 FHB resistance on chromosome 4AS of Triticum macha and deployment in combination with two Type 2 resistances. | Burt C et al. | β | 2015 | β |
| Modeling HLA associations with EBV-positive and -negative Hodgkin lymphoma suggests distinct mechanisms in disease pathogenesis. | Johnson PC et al. | β | 2015 | β |
| Multi-environment multi-QTL association mapping identifies disease resistance QTL in barley germplasm from Latin America. | GutiΓ©rrez L et al. | β | 2015 | β |
| Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans. | Repunte-Canonigo V et al. | β | 2015 | β |
| Novel epigenetic determinants of type 2 diabetes in Mexican-American families. | Kulkarni H et al. | β | 2015 | β |
| Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study. | Johnson EO et al. | β | 2015 | β |
| Polymorphisms in TICAM2 and IL1B are associated with TB. | Hall NB et al. | β | 2015 | β |
| Quantitative trait loci and candidate genes underlying genotype by environment interaction in the response of Arabidopsis thaliana to drought. | El-Soda M et al. | β | 2015 | β |
| Resampling-based multiple comparison procedure with application to point-wise testing with functional data. | Vsevolozhskaya OA et al. | β | 2015 | β |
| Significant association between rare IPO11-HTR1A variants and attention deficit hyperactivity disorder in Caucasians. | Zuo L et al. | β | 2015 | β |
| Stress and Bronchodilator Response in Children with Asthma. | Brehm JM et al. | β | 2015 | β |
| The dystrophin gene and cognitive function in the general population. | Vojinovic D et al. | β | 2015 | β |
| The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. | Suchankova P et al. | β | 2015 | β |
| The role of age in association analyses of ADHD and related neurocognitive functioning: A proof of concept for dopaminergic and serotonergic genes. | Thissen AJ et al. | β | 2015 | β |
| The role of genetic variation across IL-1Ξ², IL-2, IL-6, and BDNF in antipsychotic-induced weight gain. | Fonseka TM et al. | β | 2015 | β |
| Validation of candidate anxiety disorder genes using a carbon dioxide challenge task. | Savage JE et al. | β | 2015 | β |
| Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans. | Todd JN et al. | β | 2015 | β |
| Accounting for linkage disequilibrium in association analysis of diverse populations. | Charles BA et al. | β | 2014 | β |
| A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. | Milne RL et al. | β | 2014 | β |
| Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. | Kim-Howard X et al. | β | 2014 | β |
| An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3. | Zochling J et al. | β | 2014 | β |
| Are genetic variations in OXTR, AVPR1A, and CD38 genes important to social integration? Results from two large U.S. cohorts. | Chang SC et al. | β | 2014 | β |
| Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders. | Stein CM et al. | β | 2014 | β |
| Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest. | DeMenna J et al. | β | 2014 | β |
| Association of OPRD1 polymorphisms with heroin dependence in a large case-control series. | Nelson EC et al. | β | 2014 | β |
| Associations between CYP19A1 polymorphisms, Native American ancestry, and breast cancer risk and mortality: the Breast Cancer Health Disparities Study. | Boone SD et al. | β | 2014 | β |
| Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence. | Zuo L et al. | β | 2014 | β |
| Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. | Olden M et al. | β | 2014 | β |
| Correction for multiple testing in a gene region. | Hendricks AE et al. | β | 2014 | β |
| CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam. | Grant AV et al. | β | 2014 | β |
| Dent and Flint maize diversity panels reveal important genetic potential for increasing biomass production. | Rincent R et al. | β | 2014 | β |
| Development and heritability of subcortical brain volumes at ages 9 and 12. | Swagerman SC et al. | β | 2014 | β |
| Diet and lifestyle factors interact with MAPK genes to influence survival: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2014 | β |
| Diet and lifestyle factors modify immune/inflammation response genes to alter breast cancer risk and prognosis: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2014 | β |
| Effect of OPRM1 and stressful life events on symptoms of major depression in African American adolescents. | Swann G et al. | β | 2014 | β |
| Epigenetic genes and emotional reactivity to daily life events: a multi-step gene-environment interaction study. | Pishva E et al. | β | 2014 | β |
| Estimating genome-wide significance for whole-genome sequencing studies. | Xu C et al. | β | 2014 | β |
| Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease. | Palmer ND et al. | β | 2014 | β |
| Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation. | Xu C et al. | β | 2014 | β |
| FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. | Agarwal D et al. | β | 2014 | β |
| Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. | Cheverud JM et al. | β | 2014 | β |
| Genetic Association of MPPED2 and ACTN2 with Dental Caries. | Stanley BO et al. | β | 2014 | β |
| Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. | Zhang X et al. | β | 2014 | β |
| Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention. | Peter I et al. | β | 2014 | β |
| Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort. | Kedenko L et al. | β | 2014 | β |
| Genetic predictors of antidepressant side effects: a grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study. | Hodgson K et al. | β | 2014 | β |
| Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2014 | β |
| Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2014 | β |
| Genome-wide association analysis identifies six new loci associated with forced vital capacity. | Loth DW et al. | β | 2014 | β |
| Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. | Galanter JM et al. | β | 2014 | β |
| Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. | Gelernter J et al. | β | 2014 | β |
| Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. | Gelernter J et al. | β | 2014 | β |
| Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. | Simpson CL et al. | β | 2014 | β |
| Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study. | Irvin MR et al. | β | 2014 | β |
| High pressure induced changes in beef muscle proteome: correlation with quality parameters. | Marcos B et al. | β | 2014 | β |
| High-resolution mapping reveals hundreds of genetic incompatibilities in hybridizing fish species. | Schumer M et al. | β | 2014 | β |
| HLA-G gene expression influenced at allelic level in association with end stage renal disease and acute allograft rejection. | Misra MK et al. | β | 2014 | β |
| Increased waist circumference is independently associated with hypothyroidism in Mexican Americans: replicative evidence from two large, population-based studies. | Mamtani M et al. | β | 2014 | β |
| Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. | Slattery ML et al. | β | 2014 | β |
| Investigating the Role of Gene-Gene Interactions in TB Susceptibility. | Daya M et al. | β | 2014 | β |
| Linking macroscale graph analytical organization to microscale neuroarchitectonics in the macaque connectome. | Scholtens LH et al. | β | 2014 | β |
| Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1. | Ramos A et al. | β | 2014 | β |
| Novel locus for fibrinogen in 3' region of LEPR gene in island population of Vis (Croatia). | Tomas Ε½ et al. | β | 2014 | β |
| Plasma levels of soluble interleukin 1 receptor accessory protein are reduced in obesity. | Bozaoglu K et al. | β | 2014 | β |
| Polygenic scores associated with educational attainment in adults predict educational achievement and ADHD symptoms in children. | de Zeeuw EL et al. | β | 2014 | β |
| Polymorphisms of SP110 are associated with both pulmonary and extra-pulmonary tuberculosis among the Vietnamese. | Fox GJ et al. | β | 2014 | β |
| Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain. | Gagliano SA et al. | β | 2014 | β |
| Replication and cross-phenotype study based upon schizophrenia GWASs data in the Japanese population: support for association of MHC region with psychosis. | Saito T et al. | β | 2014 | β |
| Results of a "GWAS plus:" general cognitive ability is substantially heritable and massively polygenic. | Kirkpatrick RM et al. | β | 2014 | β |
| Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder. | Korhonen T et al. | β | 2014 | β |
| RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS). | Shendre A et al. | β | 2014 | β |
| Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways. | Logue MW et al. | β | 2014 | β |
| Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. | Liu CT et al. | β | 2014 | β |
| Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival. | Lu S et al. | β | 2014 | β |
| Smoking and risk of multiple sclerosis: evidence of modification by NAT1 variants. | Briggs FB et al. | β | 2014 | β |
| Statistical power and significance testing in large-scale genetic studies. | Sham PC et al. | β | 2014 | β |
| The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa. | Yilmaz Z et al. | β | 2014 | β |
| The Saguenay-Lac-Saint-Jean asthma familial collection: the genetics of asthma in a young founder population. | Laprise C | β | 2014 | β |
| ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. | Johnatty SE et al. | β | 2013 | β |
| Advantage of using allele-specific copy numbers when testing for association in regions with common copy number variants. | Marenne G et al. | β | 2013 | β |
| A genome-wide scan for breast cancer risk haplotypes among African American women. | Song C et al. | β | 2013 | β |
| A method to prioritize quantitative traits and individuals for sequencing in family-based studies. | Shah KP et al. | β | 2013 | β |
| Analyses of RANK and RANKL in the post-GWAS context: functional evidence of vitamin D stimulation through a RANKL distal region. | Yoskovitz G et al. | β | 2013 | β |
| Analysis of 34 candidate genes in bupropion and placebo remission. | Tiwari AK et al. | β | 2013 | β |
| Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism. | Zuo L et al. | β | 2013 | β |
| Association of HLA-G 3' untranslated region polymorphisms with antibody response against Plasmodium falciparum antigens: preliminary results. | Sabbagh A et al. | β | 2013 | β |
| Associations between genetic variants in the TGF-Ξ² signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women. | Boone SD et al. | β | 2013 | β |
| Associations between prefrontal Ξ³-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women. | Preuss N et al. | β | 2013 | β |
| Association study of OPRM1 polymorphisms with Schizophrenia in Han Chinese population. | Ding S et al. | β | 2013 | β |
| Association study of the vesicular monoamine transporter gene SLC18A2 with tardive dyskinesia. | Zai CC et al. | β | 2013 | β |
| Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles. | Dharuri H et al. | β | 2013 | β |
| Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. | Thun GA et al. | β | 2013 | β |
| Common genetic variants in ARNTL and NPAS2 and at chromosome 12p13 are associated with objectively measured sleep traits in the elderly. | Evans DS et al. | β | 2013 | β |
| Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study. | Lim S et al. | β | 2013 | β |
| Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer. | Slattery ML et al. | β | 2013 | β |
| Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study. | Huggins GS et al. | β | 2013 | β |
| Epidermal growth factor receptor (EGFR) polymorphisms and breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. | Connor AE et al. | β | 2013 | β |
| Evidence for novel genetic loci associated with metabolic traits in Yup'ik people. | Aslibekyan S et al. | β | 2013 | β |
| Familial resemblance for serum metabolite concentrations. | Draisma HH et al. | β | 2013 | β |
| Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression. | Jamerson BD et al. | β | 2013 | β |
| FTO predicts weight regain in the Look AHEAD clinical trial. | McCaffery JM et al. | β | 2013 | β |
| Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype. | Soldano KL et al. | β | 2013 | β |
| Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans. | Carless MA et al. | β | 2013 | β |
| Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome. | Lu S et al. | β | 2013 | β |
| Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study. | Kondo K et al. | β | 2013 | β |
| Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung function. | Tang W et al. | β | 2013 | β |
| Genetic variation in bone morphogenetic proteins and breast cancer risk in hispanic and non-hispanic white women: The breast cancer health disparities study. | Slattery ML et al. | β | 2013 | β |
| Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence. | Zuo L et al. | β | 2013 | β |
| Genomic correlates of relationship QTL involved in fore- versus hind limb divergence in mice. | Pavlicev M et al. | β | 2013 | β |
| HLA-G 3' UTR-2 haplotype is associated with Human African trypanosomiasis susceptibility. | Courtin D et al. | β | 2013 | β |
| Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. | McCaffery JM et al. | β | 2013 | β |
| Identification of QTLs associated with callogenesis and embryogenesis in oil palm using genetic linkage maps improved with SSR markers. | Ting NC et al. | β | 2013 | β |
| Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). | Reitz C et al. | β | 2013 | β |
| Investigating the role of pain-modulating pathway genes in musculoskeletal pain. | Holliday KL et al. | β | 2013 | β |
| Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. | Liu Y et al. | β | 2013 | β |
| LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome. | Pinheiro I et al. | β | 2013 | β |
| Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study. | Slattery ML et al. | β | 2013 | β |
| MetaRanker 2.0: a web server for prioritization of genetic variation data. | Pers TH et al. | β | 2013 | β |
| Multi-environment analysis and improved mapping of a yield-related QTL on chromosome 3B of wheat. | Bonneau J et al. | β | 2013 | β |
| Multi-trait and multi-environment QTL analyses of yield and a set of physiological traits in pepper. | Alimi NA et al. | β | 2013 | β |
| NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. | Zuo L et al. | β | 2013 | β |
| No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes. | Tesli M et al. | β | 2013 | β |
| Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder. | Kim BN et al. | β | 2013 | β |
| On multi-marker tests for association in case-control studies. | Taub MA et al. | β | 2013 | β |
| QTL dissection of the loss of green colour during post-anthesis grain maturation in two-rowed barley. | Emebiri LC | β | 2013 | β |
| QTL for yield and associated traits in the Seri/Babax population grown across several environments in Mexico, in the West Asia, North Africa, and South Asia regions. | Lopes MS et al. | β | 2013 | β |
| Rare ADH variant constellations are specific for alcohol dependence. | Zuo L et al. | β | 2013 | β |
| Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. | Zuo L et al. | β | 2013 | β |
| Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls. | Lamontagne M et al. | β | 2013 | β |
| SEPP1 influences breast cancer risk among women with greater native american ancestry: the breast cancer health disparities study. | Pellatt AJ et al. | β | 2013 | β |
| Sortilin receptor 1 predicts longitudinal cognitive change. | Reynolds CA et al. | β | 2013 | β |
| Speeding up Permutation Testing in Neuroimaging. | Hinrichs C et al. | β | 2013 | β |
| Study of the catechol-o-methyltransferase (COMT) gene with high aggression in children. | Hirata Y et al. | β | 2013 | β |
| Subacute effects of ecstasy on mood: an exploration of associated risk factors. | Scott RM et al. | β | 2013 | β |
| Surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry: a tool to predict pork quality. | Marcos B et al. | β | 2013 | β |
| Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. | Pellatt AJ et al. | β | 2013 | β |
| The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems. | Meyers JL et al. | β | 2013 | β |
| The evidence for association of ATP2B2 polymorphisms with autism in Chinese Han population. | Yang W et al. | β | 2013 | β |
| The statistical analysis of multi-environment data: modeling genotype-by-environment interaction and its genetic basis. | Malosetti M et al. | β | 2013 | β |
| Variability in associations of phosphatidylcholine molecular species with metabolic syndrome in Mexican-American families. | Kulkarni H et al. | β | 2013 | β |
| Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program. | Pan Q et al. | β | 2013 | β |
| Weighted SNP set analysis in genome-wide association study. | Dai H et al. | β | 2013 | β |
| A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer. | Campa D et al. | β | 2012 | β |
| A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis. | Campa D et al. | β | 2012 | β |
| A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs. | Docherty SJ et al. | β | 2012 | β |
| AGTR1 gene variation: association with depression and frontotemporal morphology. | Taylor WD et al. | β | 2012 | β |
| Alcohol and aggressive behavior in men--moderating effects of oxytocin receptor gene (OXTR) polymorphisms. | Johansson A et al. | β | 2012 | β |
| Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits. | Broms U et al. | β | 2012 | β |
| Are single nucleotide polymorphisms in the oxytocin and vasopressin 1A/1B receptor genes likely candidates for variation in ejaculatory function? | Jern P et al. | β | 2012 | β |
| Association analysis of STX1A gene variants in common forms of migraine. | Tropeano M et al. | β | 2012 | β |
| Association between BDNF rs6265 and obesity in the Boston Puerto Rican Health Study. | Ma XY et al. | β | 2012 | β |
| Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population. | Fujii T et al. | β | 2012 | β |
| Association between variations in cell cycle genes and idiopathic pulmonary fibrosis. | Korthagen NM et al. | β | 2012 | β |
| Association of adiponectin polymorphism with cord blood adiponectin concentrations and intrauterine growth. | Saito M et al. | β | 2012 | β |
| Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe). | Patel SR et al. | β | 2012 | β |
| Associations between nitric oxide synthase genes and exhaled NO-related phenotypes according to asthma status. | Bouzigon E et al. | β | 2012 | β |
| Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. | Connor AE et al. | β | 2012 | β |
| Association study of cannabinoid receptor 1 (CNR1) gene in tardive dyskinesia. | Tiwari AK et al. | β | 2012 | β |
| Association study of early-immediate genes in childhood-onset mood disorders and suicide attempt. | Strauss J et al. | β | 2012 | β |
| Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies. | Hirata Y et al. | β | 2012 | β |
| A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations. | Wang X et al. | β | 2012 | β |
| Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation. | Kloss-BrandstΓ€tter A et al. | β | 2012 | β |
| CD1 gene polymorphisms and phenotypic variability in X-linked adrenoleukodystrophy. | Barbier M et al. | β | 2012 | β |
| Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia. | Jamshidi Y et al. | β | 2012 | β |
| Crop to wild introgression in lettuce: following the fate of crop genome segments in backcross populations. | Uwimana B et al. | β | 2012 | β |
| Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent. | Al-Eitan LN et al. | β | 2012 | β |
| Design and analysis of multiple diseases genome-wide association studies without controls. | Chen Z et al. | β | 2012 | β |
| Detecting maternal-effect loci by statistical cross-fostering. | Wolf J et al. | β | 2012 | β |
| Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy. | Igo RP et al. | β | 2012 | β |
| Dopamine transporter genotype predicts behavioural and neural measures of response inhibition. | Cummins TD et al. | β | 2012 | β |
| Epistatic Control of Mammary Cancer Susceptibility in Mice may Depend on the Dietary Environment. | Leamy LJ et al. | β | 2012 | β |
| Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets. | Li MX et al. | β | 2012 | β |
| Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders. | Ersland KM et al. | β | 2012 | β |
| Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations. | Sorice R et al. | β | 2012 | β |
| Genetic architecture of nest building in mice LG/JβΓβSM/J. | Sauce B et al. | β | 2012 | β |
| Genetic control of duration of pre-anthesis phases in wheat (Triticum aestivum L.) and relationships to leaf appearance, tillering, and dry matter accumulation. | BorrΓ s-Gelonch G et al. | β | 2012 | β |
| Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations. | Bevan S et al. | β | 2012 | β |
| Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos. | Lemas DJ et al. | β | 2012 | β |
| Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts. | Kedenko L et al. | β | 2012 | β |
| Genetic polymorphisms of the Wnt receptor LRP5 are differentially associated with trochanteric and cervical hip fractures. | Riancho J et al. | β | 2012 | β |
| Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. | Traylor M et al. | β | 2012 | β |
| Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass. | Cummings N et al. | β | 2012 | β |
| Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project. | Perroud N et al. | β | 2012 | β |
| Genotype-dependent responses to levels of sibling competition over maternal resources in mice. | Hager R et al. | β | 2012 | β |
| Healing quantitative trait loci in a combined cross analysis using related mouse strain crosses. | Cheverud JM et al. | β | 2012 | β |
| HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq. | Jassem RM et al. | β | 2012 | β |
| Hybridization between crops and wild relatives: the contribution of cultivated lettuce to the vigour of crop-wild hybrids under drought, salinity and nutrient deficiency conditions. | Uwimana B et al. | β | 2012 | β |
| Identification of Alzheimer disease-associated variants in genes that regulate retromer function. | Vardarajan BN et al. | β | 2012 | β |
| Identification of common variants associated with human hippocampal and intracranial volumes. | Stein JL et al. | β | 2012 | β |
| Identification of plant quantitative trait loci modulating a rhizobacteria-aphid indirect effect. | TΓ©tard-Jones C et al. | β | 2012 | β |
| Impact of common variation in bone-related genes on type 2 diabetes and related traits. | Billings LK et al. | β | 2012 | β |
| IndOR: a new statistical procedure to test for SNP-SNP epistasis in genome-wide association studies. | Emily M | β | 2012 | β |
| Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium. | Kazma R et al. | β | 2012 | β |
| MAP kinase genes and colon and rectal cancer. | Slattery ML et al. | β | 2012 | β |
| Maternal transmission effect of a PDGF-C SNP on nonsyndromic cleft lip with or without palate from a Chinese population. | Wu D et al. | β | 2012 | β |
| Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. | Stolk L et al. | β | 2012 | β |
| Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. | Farook VS et al. | β | 2012 | β |
| Milk ejection in mice LG/J x SM/J. | GΓ³es CP et al. | β | 2012 | β |
| Multi-trait and multi-environment QTL analyses for resistance to wheat diseases. | Sukhwinder-Singh et al. | β | 2012 | β |
| NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. | Sandford AJ et al. | β | 2012 | β |
| Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice. | Kraja AT et al. | β | 2012 | β |
| Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. | McCaffery JM et al. | β | 2012 | β |
| Organ specificity and transcriptional control of metabolic routes revealed by expression QTL profiling of source--sink tissues in a segregating potato population. | Kloosterman B et al. | β | 2012 | β |
| PERMORY-MPI: a program for high-speed parallel permutation testing in genome-wide association studies. | SteiΓ V et al. | β | 2012 | β |
| Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. | Bader V et al. | β | 2012 | β |
| Quantitative trait loci affecting liver fat content in mice. | Minkina O et al. | β | 2012 | β |
| Rapid and robust resampling-based multiple-testing correction with application in a genome-wide expression quantitative trait loci study. | Zhang X et al. | β | 2012 | β |
| Relationship between DDAH gene variants and serum ADMA level in individuals with type 1 diabetes. | Fogarty RD et al. | β | 2012 | β |
| STAT6 and LRP1 polymorphisms are associated with food allergen sensitization in Mexican children. | Hancock DB et al. | β | 2012 | β |
| The analysis of ethnic mixtures. | Zhu X | β | 2012 | β |
| The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses. | Lubke GH et al. | β | 2012 | β |
| The cost of large numbers of hypothesis tests on power, effect size and sample size. | Lazzeroni LC et al. | β | 2012 | β |
| The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. | Thameem F et al. | β | 2012 | β |
| The mode of inheritance in tetraploid cut roses. | Koning-Boucoiran CF et al. | β | 2012 | β |
| The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain. | Zai GC et al. | β | 2012 | β |
| The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk. | Hamilton G et al. | β | 2012 | β |
| Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. | Liu CT et al. | β | 2012 | β |
| Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children. | Tavassoli T et al. | β | 2012 | β |
| Variations in the potassium channel genes KCNK3 and KCNK9 in relation to blood pressure and aldosterone production: an exploratory study. | Jung J et al. | β | 2012 | β |
| Weak genetic relationship between trabecular bone morphology and obesity in mice. | Carson EA et al. | β | 2012 | β |
| Weighted multiple testing correction for correlated tests. | Xie C | β | 2012 | β |
| Weighted multiple testing procedures for genomic studies. | Gui J et al. | β | 2012 | β |
| A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. | Obeidat M et al. | β | 2011 | β |
| A general method for controlling the genome-wide type I error rate in linkage and association mapping experiments in plants. | MΓΌller BU et al. | β | 2011 | β |
| A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation. | Kastelijn EA et al. | β | 2011 | β |
| Alzheimer's disease genes are associated with measures of cognitive ageing in the lothian birth cohorts of 1921 and 1936. | Hamilton G et al. | β | 2011 | β |
| A new approach to account for the correlations among single nucleotide polymorphisms in genome: wide association studies. | Chen Z et al. | β | 2011 | β |
| A polymorphism of the ABCA1 gene confers susceptibility to schizophrenia and related brain changes. | Ota M et al. | β | 2011 | β |
| Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. | Ittiwut R et al. | β | 2011 | β |
| Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts. | Nicholl BI et al. | β | 2011 | β |
| Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting. | Slof-Op 't Landt MC et al. | β | 2011 | β |
| Blood pressure loci identified with a gene-centric array. | Johnson T et al. | β | 2011 | β |
| Candidate gene association study of magnetic resonance imaging-based hip osteoarthritis (OA): evidence for COL9A2 gene as a common predisposing factor for hip OA and lumbar disc degeneration. | NΓ€kki A et al. | β | 2011 | β |
| Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample. | Perroud N et al. | β | 2011 | β |
| Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. | Zhu X et al. | β | 2011 | β |
| Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders. | Chang SC et al. | β | 2011 | β |
| Common polymorphisms in FMO1 are associated with nicotine dependence. | Hinrichs AL et al. | β | 2011 | β |
| Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants. | Malki K et al. | β | 2011 | β |
| Converging evidence for an association of ATP2B2 allelic variants with autism in male subjects. | Carayol J et al. | β | 2011 | β |
| Direct assessment of multiple testing correction in case-control association studies with related individuals. | Wang Z | β | 2011 | β |
| Disentangling prenatal and postnatal maternal genetic effects reveals persistent prenatal effects on offspring growth in mice. | Wolf JB et al. | β | 2011 | β |
| Epistatic interactions of genes influence within-individual variation of physical activity traits in mice. | Leamy LJ et al. | β | 2011 | β |
| Evolution of pleiotropy: epistatic interaction pattern supports a mechanistic model underlying variation in genotype-phenotype map. | Pavlicev M et al. | β | 2011 | β |
| Factors affecting the effective number of tests in genetic association studies: a comparative study of three PCA-based methods. | Wen SH et al. | β | 2011 | β |
| Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. | Kauwe JS et al. | β | 2011 | β |
| Gene-based tests of association. | Huang H et al. | β | 2011 | β |
| Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations. | Lawson HA et al. | β | 2011 | β |
| Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes. | Syreeni A et al. | β | 2011 | β |
| Genetic factors and diet affect long-bone length in the F34 LG,SM advanced intercross. | Norgard EA et al. | β | 2011 | β |
| Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis. | Juran BD et al. | β | 2011 | β |
| Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms. | Ruggiero D et al. | β | 2011 | β |
| Genetic variation in DNA repair pathway genes and melanoma risk. | Zhang M et al. | β | 2011 | β |
| Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. | Wang H et al. | β | 2011 | β |
| Genomewide association scan of suicidal thoughts and behaviour in major depression. | Schosser A et al. | β | 2011 | β |
| High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis. | Rahman P et al. | β | 2011 | β |
| Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia. | Hadchouel A et al. | β | 2011 | β |
| IFNG genotype and sex interact to influence the risk of childhood asthma. | Loisel DA et al. | β | 2011 | β |
| Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in men. | Roshandel D et al. | β | 2011 | β |
| Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers. | Swamy GK et al. | β | 2011 | β |
| Multilocus association testing of quantitative traits based on partial least-squares analysis. | Zhang F et al. | β | 2011 | β |
| Multiple testing corrections for imputed SNPs. | Gao X | β | 2011 | β |
| MYH9 and APOL1 are both associated with sickle cell disease nephropathy. | Ashley-Koch AE et al. | β | 2011 | β |
| Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. | Pande M et al. | β | 2011 | β |
| On the use of multifactor dimensionality reduction (MDR) and classification and regression tree (CART) to identify haplotype-haplotype interactions in genetic studies. | Hsieh AR et al. | β | 2011 | β |
| Polymorphisms in genes involved in the NF-ΞΊB signalling pathway are associated with bone mineral density, geometry and turnover in men. | Roshandel D et al. | β | 2011 | β |
| Possible association between interleukin-1Ξ² gene and schizophrenia in a Japanese population. | Sasayama D et al. | β | 2011 | β |
| Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. | Smith SB et al. | β | 2011 | β |
| Quantitative trait loci mapping of phenotypic plasticity and genotype-environment interactions in plant and insect performance. | TΓ©tard-Jones C et al. | β | 2011 | β |
| Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice. | Leamy LJ et al. | β | 2011 | β |
| The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults. | Ye X et al. | β | 2011 | β |
| The importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J Γ SM/J murine model. | Lawson HA et al. | β | 2011 | β |
| Variants in STAT5B associate with serum TC and LDL-C levels. | Kornfeld JW et al. | β | 2011 | β |
| Variation in genes involved in dopamine clearance influence the startle response in older adults. | Armbruster D et al. | β | 2011 | β |
| Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces. | Chakrabarti B et al. | β | 2011 | β |
| Altered cardiac repolarization in association with air pollution and air temperature among myocardial infarction survivors. | Hampel R et al. | β | 2010 | β |
| A novel statistic for genome-wide interaction analysis. | Wu X et al. | β | 2010 | β |
| Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer. | Mrkonjic M et al. | β | 2010 | β |