GWAF: an R package for genome-wide association analyses with family data.
paper
Cited
Public
Unavailable
- Authors
- Chen, Ming-Huei; Yang, Qiong
- Year
- 2010
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 20040588
- DOI
- 10.1093/bioinformatics/btp710
- PMCID
- PMC2852219
GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry. | Ray NR et al. | β | 2024 | β |
| Factors that modulate platelet reactivity as measured by 5 assay platforms in 3429 individuals. | Chan MV et al. | β | 2024 | β |
| Human genetics and epigenetics of alcohol use disorder. | Zhou H et al. | β | 2024 | β |
| The collaborative study on the genetics of alcoholism: Genetics. | Johnson EC et al. | β | 2023 | β |
| Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium. | FernΓ‘ndez-Rhodes L et al. | β | 2022 | β |
| Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse. | Roselli C et al. | β | 2022 | β |
| Genome-Wide Linkage and Association Study of Childhood Gender Nonconformity in Males. | Sanders AR et al. | β | 2021 | β |
| Genome-Wide Meta-Analysis of Late-Onset Alzheimerβs Disease Using Rare Variant Imputation in 65,602 Subjects Identifies Novel Rare Variant Locus <i>NCK2</i>: The International Genomics of Alzheimerβs Project (IGAP) | Naj AC et al. | β | 2021 | β |
| Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults. | Katz DH et al. | β | 2021 | β |
| Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk. | Ngo D et al. | β | 2021 | β |
| A Family-Based Genome Wide Association Study of Externalizing Behaviors. | Barr PB et al. | β | 2020 | β |
| Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. | Ouellette AR et al. | β | 2020 | β |
| Genome-wide association studies of the self-rating of effects of ethanol (SRE). | Lai D et al. | β | 2020 | β |
| Modeling the Dependence Structure in Genome Wide Association Studies of Binary Phenotypes in Family Data. | Seal S et al. | β | 2020 | β |
| QTL mapping and marker identification for sex determination in the ridgetail white prawn, Exopalaemon carinicauda. | Lv J et al. | β | 2020 | β |
| A High-Density Genetic Linkage Map and QTL Mapping for Sex in Black Tiger Shrimp (<i>Penaeus monodon</i>). | Guo L et al. | β | 2019 | β |
| A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans. | Cheng Z et al. | β | 2019 | β |
| Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates AΞ², tau, immunity and lipid processing. | Kunkle BW et al. | β | 2019 | β |
| Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. | Lai D et al. | β | 2019 | β |
| Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. | Wetherill L et al. | β | 2019 | β |
| Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. | Young KA et al. | β | 2019 | β |
| Human genes influence the interaction between Streptococcus mutans and host caries susceptibility: a genome-wide association study in children with primary dentition. | Meng Y et al. | β | 2019 | β |
| Profiling of the plasma proteome across different stages of human heart failure. | Egerstedt A et al. | β | 2019 | β |
| Quantitative Trait Loci Mapping and Marker Identification for Low Salinity Tolerance Trait in the Swimming Crab (<i>Portunus trituberculatus</i>). | Lv J et al. | β | 2019 | β |
| Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. | Tin A et al. | β | 2019 | β |
| The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study. | de Toro-MartΓn J et al. | β | 2019 | β |
| Variation in SIPA1L2 is correlated with phenotype modification in Charcot- Marie- Tooth disease type 1A. | Tao F et al. | β | 2019 | β |
| A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus. | Polimanti R et al. | β | 2018 | β |
| Analysis of genetic and nongenetic factors influencing triglycerides-lowering drug effects based on paired observations. | Xu Z et al. | β | 2018 | β |
| A tutorial on conducting genome-wide association studies: Quality control and statistical analysis. | Marees AT et al. | β | 2018 | β |
| Effects of Serotonin Transporter Gene Variation on Impulsivity Mediated by Default Mode Network: A Family Study of Depression. | Cha J et al. | β | 2018 | β |
| Genetic Architecture of the Cardiovascular Risk Proteome. | Benson MD et al. | β | 2018 | β |
| Genome-wide association study identifies a novel locus for cannabis dependence. | Agrawal A et al. | β | 2018 | β |
| Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test. | Zhang H et al. | β | 2018 | β |
| High-resolution genetic linkage map of European pear (Pyrus communis) and QTL fine-mapping of vegetative budbreak time. | Gabay G et al. | β | 2018 | β |
| Incorporating methylation genome information improves prediction accuracy for drug treatment responses. | Xia X et al. | β | 2018 | β |
| Investigating multiple sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci. | Fazia T et al. | β | 2018 | β |
| Kernel machine SNP set analysis provides new insight into the association between obesity and polymorphisms located on the chromosomal 16q.12.2 region: Tehran Lipid and Glucose Study. | Javanrouh N et al. | β | 2018 | β |
| PLINK: Key Functions for Data Analysis. | Slifer SH | β | 2018 | β |
| PM20D1 is aΒ quantitative trait locus associated with Alzheimer's disease. | Sanchez-Mut JV et al. | β | 2018 | β |
| QTL Mapping and Marker Identification for Sex-Determining: Indicating XY Sex Determination System in the Swimming Crab (<i>Portunus trituberculatus</i>). | Lv J et al. | β | 2018 | β |
| The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. | FernΓ‘ndez-Rhodes L et al. | β | 2018 | β |
| The polymorphism rs6918289 located in the downstream region of the TREM2 gene is associated with TNF-Ξ± levels and IMT-F. | Gorenjak V et al. | β | 2018 | β |
| Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. | Walters RK et al. | β | 2018 | β |
| A genome wide association study of fast beta EEG in families of European ancestry. | Meyers JL et al. | β | 2017 | β |
| Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors. | Polimanti R et al. | β | 2017 | β |
| An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. | Meyers JL et al. | β | 2017 | β |
| Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. | McDonald MN et al. | β | 2017 | β |
| Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes. | O'Sullivan JF et al. | β | 2017 | β |
| Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data. | Zhou H et al. | β | 2017 | β |
| Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations. | Yoneyama S et al. | β | 2017 | β |
| Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. | Busch R et al. | β | 2017 | β |
| Genetic Correlates of Spirituality/Religion and Depression: A Study in Offspring and Grandchildren at High and Low Familial Risk for Depression. | Anderson MR et al. | β | 2017 | β |
| Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. | Zhou H et al. | β | 2017 | β |
| Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study. | Singh J et al. | β | 2017 | β |
| Genome-wide association study of body mass index in subjects with alcohol dependence. | Polimanti R et al. | β | 2017 | β |
| Genome-Wide Association Study of Male Sexual Orientation. | Sanders AR et al. | β | 2017 | β |
| IL6R haplotype rs4845625*T/rs4537545*C is a risk factor for simultaneously high CRP, LDL and ApoB levels. | Arguinano AA et al. | β | 2017 | β |
| <i>S100A10</i> identified in a genome-wide gene Γ cannabis dependence interaction analysis of risky sexual behaviours. | Polimanti R et al. | β | 2017 | β |
| Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. | Zillikens MC et al. | β | 2017 | β |
| Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers. | Polimanti R et al. | β | 2017 | β |
| The Association of Estrogen Receptor-Ξ² Gene Variation With Salt-Sensitive Blood Pressure. | Manosroi W et al. | β | 2017 | β |
| The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. | Polimanti R et al. | β | 2017 | β |
| Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci. | FernΓ‘ndez-Rhodes L et al. | β | 2017 | β |
| An exome array study of the plasma metabolome. | Rhee EP et al. | β | 2016 | β |
| Cardiovascular diseases-related <i>GNB3</i> C825T polymorphism has a significant sex-specific effect on serum soluble E-selectin levels. | Gbadoe KM et al. | β | 2016 | β |
| Common variants in DRD2 are associated with sleep duration: the CARe consortium. | Cade BE et al. | β | 2016 | β |
| Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. | Evans DS et al. | β | 2016 | β |
| Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis. | Manichaikul A et al. | β | 2016 | β |
| Genetic variation in NIN1 and C/VIF1 genes is significantly associated with Populus angustifolia resistance to a galling herbivore, Pemphigus betae. | Zinkgraf MS et al. | β | 2016 | β |
| Genome-wide association study of serum iron phenotypes in premenopausal women of European descent. | Koller DL et al. | β | 2016 | β |
| Linkage Analysis of High-density SNPs Confirms Keratoconus Locus at 5q Chromosomal Region. | Bykhovskaya Y et al. | β | 2016 | β |
| Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects. | Drenos F et al. | β | 2016 | β |
| Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. | Jaeger PA et al. | β | 2016 | β |
| A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. | Chen W et al. | β | 2015 | β |
| A guide to genome-wide association analysis and post-analytic interrogation. | Reed E et al. | β | 2015 | β |
| Dissecting ancestry genomic background in substance dependence genome-wide association studies. | Polimanti R et al. | β | 2015 | β |
| Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans. | Tang W et al. | β | 2015 | β |
| Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. | Palmer ND et al. | β | 2015 | β |
| Genetic variants within the serotonin transporter associated with familial risk for major depression. | Talati A et al. | β | 2015 | β |
| Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior. | Salvatore JE et al. | β | 2015 | β |
| Genome-wide association study for endothelial growth factors. | Lieb W et al. | β | 2015 | β |
| Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. | Lieb W et al. | β | 2015 | β |
| High-density linkage mapping aided by transcriptomics documents ZW sex determination system in the Chinese mitten crab Eriocheir sinensis. | Cui Z et al. | β | 2015 | β |
| Insulin receptor variants and obesity-related cancers in the Framingham Heart Study. | Parekh N et al. | β | 2015 | β |
| Interaction between Common Genetic Variants and Total Fat Intake on Low-Density Lipoprotein Peak Particle Diameter: A Genome-Wide Association Study. | Rudkowska I et al. | β | 2015 | β |
| Peroxisome proliferator-activated receptors Ξ± and Ξ³ are linked with alcohol consumption in mice and withdrawal and dependence in humans. | Blednov YA et al. | β | 2015 | β |
| Polygenic risk for externalizing disorders: Gene-by-development and gene-by-environment effects in adolescents and young adults. | Salvatore JE et al. | β | 2015 | β |
| Positive Selection on Loci Associated with Drug and Alcohol Dependence. | Sadler B et al. | β | 2015 | β |
| The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains. | Eicher JD et al. | β | 2015 | β |
| The JAK2 46/1 haplotype does not predispose to CALR-mutated myeloproliferative neoplasms. | Soler G et al. | β | 2015 | β |
| Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families. | Shetty PB et al. | β | 2015 | β |
| A candidate gene association study for nine economically important traits in Italian Holstein cattle. | Fontanesi L et al. | β | 2014 | β |
| Adjusting family relatedness in data-driven burden test of rare variants. | Zhang Q et al. | β | 2014 | β |
| Admixture fine-mapping in African Americans implicates XAF1 as a possible sarcoidosis risk gene. | Levin AM et al. | β | 2014 | β |
| A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups. | Weng LC et al. | β | 2014 | β |
| A multi-level model for analyzing whole genome sequencing family data with longitudinal traits. | Chen T et al. | β | 2014 | β |
| APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema. | Burkart KM et al. | β | 2014 | β |
| Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders. | Stein CM et al. | β | 2014 | β |
| Association of NOD2 and IL23R with inflammatory bowel disease in Puerto Rico. | Ballester V et al. | β | 2014 | β |
| Cognitive mediators and disparities in the relation between teen depressiveness and smoking. | Mistry R et al. | β | 2014 | β |
| Dietary modulators of statin efficacy in cardiovascular disease and cognition. | Wang H et al. | β | 2014 | β |
| Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. | Avery CL et al. | β | 2014 | β |
| Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. | Ganesh SK et al. | β | 2014 | β |
| Efficient generalized least squares method for mixed population and family-based samples in genome-wide association studies. | Li J et al. | β | 2014 | β |
| Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels. | Ma Q et al. | β | 2014 | β |
| Genome-wide interaction of genotype by erythrocyte n-3 fatty acids contributes to phenotypic variance of diabetes-related traits. | Zheng JS et al. | β | 2014 | β |
| Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. | Williams SR et al. | β | 2014 | β |
| Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. | Kapoor M et al. | β | 2014 | β |
| High-resolution linkage and quantitative trait locus mapping aided by genome survey sequencing: building up an integrative genomic framework for a bivalve mollusc. | Jiao W et al. | β | 2014 | β |
| Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. | Ellis J et al. | β | 2014 | β |
| Mapping of a blood pressure QTL on chromosome 17 in American Indians of the strong heart family study. | Franceschini N et al. | β | 2014 | β |
| Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. | Ng MC et al. | β | 2014 | β |
| Native American ancestry, lung function, and COPD in Costa Ricans. | Chen W et al. | β | 2014 | β |
| The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function. | Wang YJ et al. | β | 2014 | β |
| Ξ²-Aminoisobutyric acid induces browning of white fat and hepatic Ξ²-oxidation and is inversely correlated with cardiometabolic risk factors. | Roberts LD et al. | β | 2014 | β |
| Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus. | Divers J et al. | β | 2013 | β |
| A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. | Wang JC et al. | β | 2013 | β |
| A genome-wide association study of the human metabolome in a community-based cohort. | Rhee EP et al. | β | 2013 | β |
| A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. | Kapoor M et al. | β | 2013 | β |
| An association between the calpastatin (CAST) gene and keratoconus. | Li X et al. | β | 2013 | β |
| Association of ANXA11 genetic variation with sarcoidosis in African Americans and European Americans. | Levin AM et al. | β | 2013 | β |
| A variant in the LRRFIP1 gene is associated with adiposity and inflammation. | Plourde M et al. | β | 2013 | β |
| CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients. | Horswell SD et al. | β | 2013 | β |
| Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. | Cohen KS et al. | β | 2013 | β |
| Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. | Ho JE et al. | β | 2013 | β |
| Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. | Deo R et al. | β | 2013 | β |
| GEE-based SNP set association test for continuous and discrete traits in family-based association studies. | Wang X et al. | β | 2013 | β |
| Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study. | Liao SY et al. | β | 2013 | β |
| Genetic association of COL5A1 variants in keratoconus patients suggests a complex connection between corneal thinning and keratoconus. | Li X et al. | β | 2013 | β |
| Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance. | Zheng JS et al. | β | 2013 | β |
| Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. | Franceschini N et al. | β | 2013 | β |
| Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. | Chen Z et al. | β | 2013 | β |
| Genome-wide association study in a Chinese population with diabetic retinopathy. | Sheu WH et al. | β | 2013 | β |
| Genome-wide association study in Han Chinese identifies three novel loci for human height. | Hao Y et al. | β | 2013 | β |
| Genome-wide association study of gene by smoking interactions in coronary artery calcification. | Polfus LM et al. | β | 2013 | β |
| Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. | Zheng JS et al. | β | 2013 | β |
| Loci influencing blood pressure identified using a cardiovascular gene-centric array. | Ganesh SK et al. | β | 2013 | β |
| Polyunsaturated Fatty Acids Modulate the Association between PIK3CA-KCNMB3 Genetic Variants and Insulin Resistance. | Zheng JS et al. | β | 2013 | β |
| Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. | Goodarzi MO et al. | β | 2013 | β |
| Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. | Wu Y et al. | β | 2013 | β |
| Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. | Ng MC et al. | β | 2013 | β |
| A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries. | Li X et al. | β | 2012 | β |
| A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. | Qayyum R et al. | β | 2012 | β |
| A multicenter study to map genes for Fuchs endothelial corneal dystrophy: baseline characteristics and heritability. | Louttit MD et al. | β | 2012 | β |
| Analysis of family- and population-based samples in cohort genome-wide association studies. | Manichaikul A et al. | β | 2012 | β |
| Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. | Helgadottir A et al. | β | 2012 | β |
| Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe). | Patel SR et al. | β | 2012 | β |
| Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis. | Manichaikul A et al. | β | 2012 | β |
| Clinical and genetic correlates of growth differentiation factor 15 in the community. | Ho JE et al. | β | 2012 | β |
| Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy. | Igo RP et al. | β | 2012 | β |
| Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. | Ramasamy A et al. | β | 2012 | β |
| Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. | Huang J et al. | β | 2012 | β |
| Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis. | Guo X et al. | β | 2012 | β |
| Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. | Musunuru K et al. | β | 2012 | β |
| Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. | Butler AM et al. | β | 2012 | β |
| Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis. | Manichaikul A et al. | β | 2012 | β |
| RNA-Seq identifies SNP markers for growth traits in rainbow trout. | Salem M et al. | β | 2012 | β |
| Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms. | Chiang CW et al. | β | 2012 | β |
| Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. | Chen MH et al. | β | 2012 | β |
| Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies. | Bykhovskaya Y et al. | β | 2012 | β |
| A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. | Chen MH et al. | β | 2011 | β |
| A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium. | Taylor KC et al. | β | 2011 | β |
| A rapid generalized least squares model for a genome-wide quantitative trait association analysis in families. | Li X et al. | β | 2011 | β |
| Assessment of genetic determinants of the association of Ξ³' fibrinogen in relation to cardiovascular disease. | Lovely RS et al. | β | 2011 | β |
| Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. | Fox ER et al. | β | 2011 | β |
| Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe). | Wassel CL et al. | β | 2011 | β |
| A strategy analysis for genetic association studies with known inbreeding. | Cabras S et al. | β | 2011 | β |
| Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. | Zhu X et al. | β | 2011 | β |
| Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. | Naj AC et al. | β | 2011 | β |
| CUBN is a gene locus for albuminuria. | BΓΆger CA et al. | β | 2011 | β |
| Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. | Lo KS et al. | β | 2011 | β |
| Genetic predictors of fibrin D-dimer levels in healthy adults. | Smith NL et al. | β | 2011 | β |
| Genome-wide association of copy-number variation reveals an association between short stature and the presence of low-frequency genomic deletions. | Dauber A et al. | β | 2011 | β |
| Genome-wide association studies of the PR interval in African Americans. | Smith JG et al. | β | 2011 | β |
| Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. | Tin A et al. | β | 2011 | β |
| Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. | Lettre G et al. | β | 2011 | β |
| Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). | Reiner AP et al. | β | 2011 | β |
| Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. | Faraday N et al. | β | 2011 | β |
| Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. | Debette S et al. | β | 2011 | β |
| Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. | Jun G et al. | β | 2011 | β |
| Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. | Dehghan A et al. | β | 2011 | β |
| Variants on chromosome 6p22.3 associated with blood pressure in the HyperGEN study: follow-up of FBPP quantitative trait loci. | Simino J et al. | β | 2011 | β |
| Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. | Musunuru K et al. | β | 2010 | β |
| A three-stage approach for genome-wide association studies with family data for quantitative traits. | Chen MH et al. | β | 2010 | β |
| Candidate gene association resource (CARe): design, methods, and proof of concept. | Musunuru K et al. | β | 2010 | β |
| Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. | Johnson AD et al. | β | 2010 | β |
| SNPTransformer: a lightweight toolkit for genome-wide association studies. | Dong C | β | 2010 | β |