Late-life alcohol consumption and 20-year mortality.
- Authors
- Holahan, Charles J; Schutte, Kathleen K; Brennan, Penny L; Holahan, Carole K; Moos, Bernice S; Moos, Rudolf H
- Year
- 2010
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 20735372
- DOI
- 10.1111/j.1530-0277.2010.01286.x
BACKGROUND: Growing epidemiological evidence indicates that moderate alcohol consumption is associated with reduced total mortality among middle-aged and older adults. However, the salutary effect of moderate drinking may be overestimated owing to confounding factors. Abstainers may include former problem drinkers with existing health problems and may be atypical compared to drinkers in terms of sociodemographic and social-behavioral factors. The purpose of this study was to examine the association between alcohol consumption and all-cause mortality over 20 years among 1,824 older adults, controlling for a wide range of potential confounding factors associated with abstention. METHODS: The sample at baseline included 1,824 individuals between the ages of 55 and 65. The database at baseline included information on daily alcohol consumption, sociodemographic factors, former problem drinking status, health factors, and social-behavioral factors. Abstention was defined as abstaining from alcohol at baseline. Death across a 20-year follow-up period was confirmed primarily by death certificate. RESULTS: Controlling only for age and gender, compared to moderate drinkers, abstainers had a more than 2 times increased mortality risk, heavy drinkers had 70% increased risk, and light drinkers had 23% increased risk. A model controlling for former problem drinking status, existing health problems, and key sociodemographic and social-behavioral factors, as well as for age and gender, substantially reduced the mortality effect for abstainers compared to moderate drinkers. However, even after adjusting for all covariates, abstainers and heavy drinkers continued to show increased mortality risks of 51 and 45%, respectively, compared to moderate drinkers. CONCLUSIONS: Findings are consistent with an interpretation that the survival effect for moderate drinking compared to abstention among older adults reflects 2 processes. First, the effect of confounding factors associated with alcohol abstention is considerable. However, even after taking account of traditional and nontraditional covariates, moderate alcohol consumption continued to show a beneficial effect in predicting mortality risk.
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|---|---|---|---|---|
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| History of drinking problems diminishes the protective effects of within-guideline drinking on 18-year risk of dementia and CIND. | Brennan PL et al. | — | 2021 | → |
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| Factors Associated With High-Risk Alcohol Consumption Among LGB Older Adults: The Roles of Gender, Social Support, Perceived Stress, Discrimination, and Stigma. | Bryan AE et al. | — | 2017 | → |
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| Lifecourse transitions, gender and drinking in later life. | Holdsworth C et al. | — | 2017 | → |
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| Alcohol consumption in the elderly and risk of dementia related death--a Norwegian prospective study with a 17-year follow-up. | Ormstad H et al. | — | 2016 | → |
| Feasibility and Utility of Experience Sampling to Assess Alcohol Consumption Among Older Adults. | Sacco P et al. | — | 2016 | → |
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| Multiple, but not traditional risk factors predict mortality in older people: the Concord Health and Ageing in Men Project. | Hirani V et al. | — | 2014 | → |
| A qualitative study of alcohol, health and identities among UK adults in later life. | Wilson GB et al. | — | 2013 | → |
| Associations between IQ and alcohol consumption in a population of young males: a large database analysis. | Müller M et al. | — | 2013 | → |
| Daily mood-drinking slopes as predictors: a new take on drinking motives and related outcomes. | Mohr CD et al. | — | 2013 | → |
| Moderate alcohol use and health: a consensus document. | Poli A et al. | — | 2013 | → |
| NONDRINKER MORTALITY RISK IN THE UNITED STATES. | Rogers RG et al. | — | 2013 | → |
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| Alcohol use patterns and trajectories of health-related quality of life in middle-aged and older adults: a 14-year population-based study. | Kaplan MS et al. | — | 2012 | → |
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| Risk of future trauma based on alcohol screening scores: a two-year prospective cohort study among US veterans. | Harris AH et al. | — | 2012 | → |
| Wine consumption and 20-year mortality among late-life moderate drinkers. | Holahan CJ et al. | — | 2012 | → |
| Does the Mediterranean diet predict longevity in the elderly? A Swedish perspective. | Tognon G et al. | — | 2011 | → |
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| Increasing and decreasing alcohol use trajectories among older women in the U.S. across a 10-year interval. | Bobo JK et al. | — | 2011 | → |