Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
paper
Cited
Public
Unavailable
- Authors
- Corder, E H; Saunders, A M; Strittmatter, W J; Schmechel, D E; Gaskell, P C; Small, G W; Roses, A D; Haines, J L; Pericak-Vance, M A
- Year
- 1993
- Journal
- Science (New York, N.Y.)
- PMID
- 8346443
- DOI
- 10.1126/science.8346443
The apolipoprotein E type 4 allele (APOE-epsilon 4) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease (AD). Risk for AD increased from 20% to 90% and mean age at onset decreased from 84 to 68 years with increasing number of APOE-epsilon 4 alleles in 42 families with late onset AD. Thus APOE-epsilon 4 gene dose is a major risk factor for late onset AD and, in these families, homozygosity for APOE-epsilon 4 was virtually sufficient to cause AD by age 80.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| 2026 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Palaniappan LP et al. | β | 2026 | β |
| A common 19βbp APOE enhancer deletion is protective against Alzheimer's disease in African Americans. | Brutman JN et al. | β | 2026 | β |
| Additive Effects of White Matter Hyperintensity and APOE Ξ΅4 Status on Risk of Incident Dementia in Two Large Longitudinal Cohorts. | de Havenon A et al. | β | 2026 | β |
| Advances in Alzheimer's disease: mechanistic insights and therapeutic targets. | Jia YJ et al. | β | 2026 | β |
| Advances in hiPSC-Derived Brain Organoids as a Model to Study Neuroinflammation in Alzheimer's Disease. | Maciel EMA et al. | β | 2026 | β |
| Advances in plasma biomarkers for the diagnosis of Alzheimer's disease. | Wu H et al. | β | 2026 | β |
| Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-Ξ²-complement mediated inflammation. | Stuard Sambhariya W et al. | β | 2026 | β |
| Alkaloids and flavonoids of Solanaceae: Mechanisms of action in neurodegenerative diseases. | Yin Q et al. | β | 2026 | β |
| Alzheimer's disease basics: we all should know. | Das S | β | 2026 | β |
| A Multimodal Latent Severity Axis for Alzheimer's Disease: Probabilistic PCA, Bayesian Trajectories, and Stage-Aware Timing Effects. | Haji B et al. | β | 2026 | β |
| An automated plasma-based proteotyping immunoassay for APOE Ξ΅4 zygosity classification in Alzheimer's disease. | Levin S et al. | β | 2026 | β |
| ApoE4 Drives Microglial Lipid Dysregulation in Alzheimer's Disease via Epigenetic Reprogramming of the Asxl1/LXRΞ±-H3K4me3 Axis. | Lin L et al. | β | 2026 | β |
| APOE4 reprograms microglial lipid metabolism in Alzheimer's disease: Mechanisms and therapeutic implications. | Chen J et al. | β | 2026 | β |
| APOE genotype differentially modulates prion pathology in a mouse model. | LiziΕczyk AM et al. | β | 2026 | β |
| Apoe genotype knowledge and its impact on cognitive beliefs and performance. | Barber SJ et al. | β | 2026 | β |
| APOE Ξ΅4 influences the widespread TDP-43 pathological subtype in sporadic amyotrophic lateral sclerosis. | Hatano Y et al. | β | 2026 | β |
| Apolipoprotein E e4 Status Predicts Memory Performance and Daily Functioning in Aging Hispanic/Latino Adults. | Lozano J et al. | β | 2026 | β |
| Association of apolipoprotein E variants on Alzheimer's disease in Latin America: A systematic review and meta-analysis. | Orellana P et al. | β | 2026 | β |
| Association of <i>SORL1</i> polymorphisms and <i>SORL1-APOE</i> Ξ΅4 interaction with risk of subjective cognitive decline and mild cognitive impairment in the Chinese population. | Meng F et al. | β | 2026 | β |
| Association of neighborhood disadvantage with Alzheimer's disease pathology and the stability of blood-based biomarker performance. | Myoraku A et al. | β | 2026 | β |
| Astrocytes and Microglia in Alzheimer's Disease: Friends, Foes, or Both? | Sharma A et al. | β | 2026 | β |
| Blood biomarkers in neurodegenerative diseases: pre-analytical, analytical, and post-analytical challenges. | Delaby C et al. | β | 2026 | β |
| Canine Cognitive Dysfunction and Alzheimer's Disease: Pathophysiological Relationships and the Impact of Glymphatic System Impairment on Neurodegeneration. | Dondi M et al. | β | 2026 | β |
| Clinical and functional evidence supporting the pathogenicity of the novel <i>PSEN1</i> p.R358P variant in early-onset Alzheimer's disease. | GarcΓa-Chialva DE et al. | β | 2026 | β |
| Contrasting associations of diastolic blood pressure with plasma amyloid, tau, and neurodegeneration biomarkers in the Health and Aging Brain Study-Health Disparities (HABS-HD). | Hayes CA et al. | β | 2026 | β |
| Dementia, cognitive impairment in Nigerians aged 90 years or older: A 20-year follow up of survivors of Ibadan study of aging cohort. | Baiyewu O et al. | β | 2026 | β |
| Dentition-Cognition Relationship in Aging Populations: A Meta-Analysis of Longitudinal Data. | Chen H et al. | β | 2026 | β |
| Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities. | Durodoye RO et al. | β | 2026 | β |
| Disrupted lipid homeostasis as a pathogenic mechanism in ABCA7-associated Alzheimer's disease risk. | Nam Y et al. | β | 2026 | β |
| Distinct CSF lipidomic profiles are associated with five proteomic subtypes in patients with Alzheimer's disease. | Malliou G et al. | β | 2026 | β |
| Educational attainment is associated with reduced functional decline in Puerto Ricans with elevated pTau181. | Dorfsman DA et al. | β | 2026 | β |
| Effect sizes of APOE e4 on the same general cognitive ability test taken by the same people from age 11 to age 90: The Lothian Birth Cohorts 1921 and 1936. | Deary IJ et al. | β | 2026 | β |
| Effects of <i>APOE</i> Ξ΅4 and amyloid pathology on longitudinal tau biomarkers, neurodegeneration, and cognitive decline in mild cognitive impairment. | Wang X et al. | β | 2026 | β |
| Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers. | Durant A et al. | β | 2026 | β |
| Genetic modifiers of APOE-Ξ΅4-associated cognitive decline. | Contreras AG et al. | β | 2026 | β |
| Genetic validation of ABI3 p.Ser209Phe variant and its effects on early brain pathology in asymptomatic elderly individuals. | KoivumΓ€ki M et al. | β | 2026 | β |
| Hyperphosphorylated tau and amyloid-Ξ² proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository. | Castellani RJ et al. | β | 2026 | β |
| Immune dysfunction in Alzheimer disease. | Butovsky O et al. | β | 2026 | β |
| Impact of Variation in APOE on Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis: Sequencing and Genotyping in General Population Cohorts. | Rasmussen KL et al. | β | 2026 | β |
| Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform. | Strickland MR et al. | β | 2026 | β |
| Modeling diseases of aging in larval zebrafish, a paradoxical yet powerful strategy. | Γzcan GG et al. | β | 2026 | β |
| Modeling the age-specific incidence of mild cognitive impairment incorporating the time-varying relationship of Alzheimer's disease biomarkers over 28 years. | Wang K et al. | β | 2026 | β |
| Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer's disease pathogenesis. | Tabuena DR et al. | β | 2026 | β |
| Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders. | Lozupone M et al. | β | 2026 | β |
| Pathway-based polygenic risk of Alzheimer's disease highlights immune genes in cognitive decline. | Romic E et al. | β | 2026 | β |
| Peripheral cancer attenuates amyloid pathology in Alzheimer's disease via cystatin-c activation of TREM2. | Li X et al. | β | 2026 | β |
| Plasma and neurostructural biomarkers in the clinical-biological characterization of early stages of the Alzheimer's disease continuum: findings from the Compostela Aging Study. | ZurrΓ³n M et al. | β | 2026 | β |
| Predicting the progression of MCI and Alzheimer's disease on structural brain integrity and other features with machine learning. | Mieling M et al. | β | 2026 | β |
| Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells. | Hong J et al. | β | 2026 | β |
| Proposed unified model of late-onset Alzheimer's disease: Chronic astrocytic and neuronal bioenergetic failure. | Garrahy JP | β | 2026 | β |
| Protective ApoE variants support neuronal function by effluxing oxidized phospholipids. | Ralhan I et al. | β | 2026 | β |
| Proteomic signatures of the APOE Ξ΅4 and APOE Ξ΅2 genetic variants and Alzheimer's disease. | Lu L et al. | β | 2026 | β |
| Relationships between heritable dementia risk factors, cardiovascular risk factors in young adulthood, and midlife neuropsychological outcomes. | Koychev I et al. | β | 2026 | β |
| Sex and APOE genotype specific brain regional vulnerability to Alzheimer's Disease. | Zeng Q et al. | β | 2026 | β |
| Sex and <i>APOE</i> Ξ΅4 Allele Shape Behavioral and Epigenetic Susceptibility to Prenatal Chlorpyrifos Exposure in Mice. | Biosca-Brull J et al. | β | 2026 | β |
| Sex-specific early cognitive changes are linked to global and pathway-specific genetic risk for Alzheimer's disease in at-risk individuals. | Genius P et al. | β | 2026 | β |
| Sialylation in the nervous system: Functions and mechanisms. | Koles K et al. | β | 2026 | β |
| Sterile innate immune mechanisms in neurodegenerative diseases. | Ealy A et al. | β | 2026 | β |
| Structural Change of ApoE-Lipid Nanoparticles Alters Receptor-Mediated Endocytosis and Induces Endosomal Disruption. | Mo Y et al. | β | 2026 | β |
| Targeting Microglial Phagocytosis for Alzheimer's Disease Management: Natural, Pharmacological, Nanoparticle, and Gene Therapy Approaches. | Raghuvanshi S et al. | β | 2026 | β |
| Ten-year longitudinal effects of physical activity and apolipoprotein E ..4 genotype on precuneus atrophy in Japanese older adults. | Yuki A et al. | β | 2026 | β |
| The apolipoprotein gene: a modulating role on brain volume and cognitive function in carriers of the fragile X premutation. | Jiraanont P et al. | β | 2026 | β |
| The Association between Glaucoma and Dementia in a National Cohort of All of Us Participants. | Pham K et al. | β | 2026 | β |
| The Association between Retinal Vascular Occlusions and Dementia: A UK Biobank Retrospective Longitudinal Study. | Gao A et al. | β | 2026 | β |
| The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease. | Barron AE et al. | β | 2026 | β |
| Understanding Neurodegenerative Diseases From the -Omics Perspective: Lessons Learnt. | Ibanez L et al. | β | 2026 | β |
| Vulnerability of anterior cingulate Von Economo neurons to FTLD-tauopathies in behavioral variant frontotemporal dementia. | Macomber A et al. | β | 2026 | β |
| 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Martin SS et al. | β | 2025 | β |
| ABCA7 deletion lowers age at onset of Alzheimer's disease and interacts with APOE Ξ΅4 synergistically in African-ancestry populations. | Akgun B et al. | β | 2025 | β |
| Advances in Research on Meningeal Lymphatic Vessels in Central Nervous System Diseases. | Shen H et al. | β | 2025 | β |
| Advances of therapeutic strategies for Alzheimer's disease. | Guo X et al. | β | 2025 | β |
| Age- and ApoE Genotype-Dependent Transcriptomic Responses to O<sub>3</sub> in the Hippocampus of Mice. | Nakamya MF et al. | β | 2025 | β |
| Age-dependent interactions of APOE isoform 4 and Alzheimer's disease neuropathology: findings from the NACC. | Hayes CA et al. | β | 2025 | β |
| Aging, Rather than Genotype, Is the Principal Contributor to Differential Gene Expression Within Targeted Replacement APOE2, APOE3, and APOE4 Mouse Brain. | Labuza A et al. | β | 2025 | β |
| AI as an accelerator for defining new problems that transcends boundaries. | Obafemi-Ajayi T et al. | β | 2025 | β |
| AI-Based Classification of Mild Cognitive Impairment and Cognitively Normal Patients. | Christodoulou R et al. | β | 2025 | β |
| Allostatic load dynamics, Alzheimer's disease biomarkers, and progression in individuals with mild cognitive impairment: findings from the Alzheimer's Disease Neuroimaging Initiative. | Souza-Talarico JN et al. | β | 2025 | β |
| Alteration of prefrontal functional connectivity in preclinical Alzheimer's disease: an fNIRS study. | Kim M et al. | β | 2025 | β |
| Altered brain morphometry and its association with cognitive decline and <i>APOE</i> gene in normal people at risk for Alzheimer's disease. | Zhao M et al. | β | 2025 | β |
| Alzheimer Disease Blood Biomarker Concentrations Across Race and Ethnicity Groups in Middle-Aged Adults. | Brickman AM et al. | β | 2025 | β |
| Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review. | Liu S et al. | β | 2025 | β |
| Alzheimer's disease and age-related macular degeneration: Shared and distinct immune mechanisms. | Butovsky O et al. | β | 2025 | β |
| Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy. | Zheng Q et al. | β | 2025 | β |
| Alzheimer's disease pathogenesis and the role of <i>APOE</i> Ξ΅4 in remodeling functional gradients of the default mode network. | Song W et al. | β | 2025 | β |
| A manifesto for Alzheimer's disease drug discovery in the era of disease-modifying therapies. | Hering H et al. | β | 2025 | β |
| Amyloid precursor protein carboxy-terminal fragments as catalyzers of endolysosomal dysfunction in Alzheimer's disease. | Vrancx C et al. | β | 2025 | β |
| An integrated view of the relationships between amyloid, tau, and inflammatory pathophysiology in Alzheimer's disease. | Arnsten AFT et al. | β | 2025 | β |
| An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration. | Leventhal MJ et al. | β | 2025 | β |
| A novel biochemical analysis for ApoE4 quantification in plasma and discrimination of homozygous and heterozygous APOE Ξ΅4 carriers. | RodrΓguez A et al. | β | 2025 | β |
| An overview of the genes and biomarkers in Alzheimer's disease. | Krishnamurthy HK et al. | β | 2025 | β |
| Anti-Amyloid Monoclonal Antibodies for Alzheimer's Disease: Evidence, ARIA Risk, and Precision Patient Selection. | Alkhalifa AE et al. | β | 2025 | β |
| APOE4 genotypes and the trajectory of biomarkers, neuroimaging, and cognitive measures in Alzheimer's Disease: A mixed-effects disease progression model. | Essenburg C et al. | β | 2025 | β |
| ApoE4 Homozygosity Is Associated With Increased Microglia Activation in Fatal COVID-19. | Hamdan A et al. | β | 2025 | β |
| APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-Ξ². | Cicognola C et al. | β | 2025 | β |
| ApoE4 requires lipidation enhancement to resolve cellular lipid and protein abnormalities following NPC1 inhibition. | Di Biase E et al. | β | 2025 | β |
| ApoE4 Upregulates GSK-3Ξ² to Aggravate Alzheimer-Like Pathologies and Cognitive Impairment in Type 2 Diabetic Mice. | Wang Y et al. | β | 2025 | β |
| APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology. | Tran KM et al. | β | 2025 | β |
| APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model. | Vanherle S et al. | β | 2025 | β |
| APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia. | Philippi SM et al. | β | 2025 | β |
| APOE genotype-dependent differences in human astrocytic energy metabolism. | Budny V et al. | β | 2025 | β |
| APOE Genotype Difference in the Biphasic Modulation of Amyloid-Ξ² Aggregation by Direct Binding and Lowering the Nucleation Barrier. | Song Z et al. | β | 2025 | β |
| APOE isoform-associated tau oligomer polymorphs differ in synaptotoxicity and seeding activity. | Moreno N et al. | β | 2025 | β |
| ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis. | Hernandez Arriaza R et al. | β | 2025 | β |
| APOE Ξ΅4 disrupts neuronal and network-level function in the anterior olfactory nucleus: Influence of age and sex. | Uzun C et al. | β | 2025 | β |
| APOE Ξ΅4-related differences in brain structure, function, and connectivity at midlife: A scoping review. | Lissaman R et al. | β | 2025 | β |
| Apolipoprotein E and Alzheimer's disease pathology in a diverse autopsy study. | Suemoto CK et al. | β | 2025 | β |
| Apolipoprotein E (APOE) and Alzheimer's disease risk in a Ugandan population: A pilot case-control study. | Lwere K et al. | β | 2025 | β |
| Apolipoprotein E (APOE) Genotype and Cognitive Outcomes of Snoring in a Large Cohort of Adolescents. | Isaiah A | β | 2025 | β |
| Apolipoproteins in Chronic Kidney Disease and Kidney Transplant: A Long Unfinished Story. | Secondulfo C et al. | β | 2025 | β |
| Artificial intelligence-driven multi-omics approaches in Alzheimer's disease: Progress, challenges, and future directions. | Ren F et al. | β | 2025 | β |
| A single fibril study reveals that ApoE inhibits the elongation of AΞ²42 fibrils in an isoform-dependent manner. | Dasadhikari S et al. | β | 2025 | β |
| Association between epigenetic mark 5-hydroxymethylcytosine and brain pathophysiology. | Kang AK et al. | β | 2025 | β |
| Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers. | Kulminski AM et al. | β | 2025 | β |
| Associations Between Polygenic Risk for Alzheimer's Disease and Grey Matter Volume Are Dependent on APOE, Pathological and Diagnostic Status. | Nocella V et al. | β | 2025 | β |
| Associations between Ultrafine Particles and Incident Dementia in Older Adults. | Zhu Q et al. | β | 2025 | β |
| Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging. | Posis AIB et al. | β | 2025 | β |
| Associations of KLOTHO-VS heterozygosity and Ξ±-Klotho protein with cerebrospinal fluid Alzheimer's disease biomarkers. | Katonova A et al. | β | 2025 | β |
| Astrocyte-Neuron Metabolic Synergies in Neurological Homeostasis and Disease. | Dong J et al. | β | 2025 | β |
| Astrocytic lipidopathy and bioenergetic failure in ApoE4-associated late-onset Alzheimer's disease: A unifying hypothesis. | Garrahy JP | β | 2025 | β |
| BDNF expression mediates verbal learning and memory in women in a cohort enriched with risk for Alzheimer's disease. | Edmunds KJ et al. | β | 2025 | β |
| Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions. | Noh MY et al. | β | 2025 | β |
| Border-associated macrophages: an emerging perspective from physiological basis and multi-disease roles to the mechanism of vascular cognitive impairment and dementia. | Li T et al. | β | 2025 | β |
| Brain aging shows nonlinear transitions, suggesting a midlife "critical window" for metabolic intervention. | Antal BB et al. | β | 2025 | β |
| BrainGeneBot: a framework for variant prioritization and generative pretrained transformer-informed interpretation across polygenic risk score studies. | Qu G et al. | β | 2025 | β |
| Brain health in Norwegian female former top-level football players: a protocol for a longitudinal cohort study. | DahlΓ©n SC et al. | β | 2025 | β |
| Brain volumes discriminate clinical dementia rating scale categories. | Christova P et al. | β | 2025 | β |
| Cardiovascular Risk Factors, Alzheimer's Disease, and the MIND Diet: A Narrative Review from Molecular Mechanisms to Clinical Outcomes. | Ataei Kachouei A et al. | β | 2025 | β |
| Causal relationships between neuroimaging phenotypes and the risk of early and late-onset alzheimer's disease. | Zhou J et al. | β | 2025 | β |
| Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers. | Fischer DL et al. | β | 2025 | β |
| Cell-specific copper dyshomeostasis mechanism in Alzheimer's disease. | Okafor M et al. | β | 2025 | β |
| Cell-specific protein expression in Alzheimer's disease prefrontal cortex. | Gholampour M et al. | β | 2025 | β |
| Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. | Wang S et al. | β | 2025 | β |
| Cerebral hypoperfusion, brain structural integrity, and cognitive impairment in older APOE4 carriers. | Pappas I et al. | β | 2025 | β |
| Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease. | Vromen EM et al. | β | 2025 | β |
| Chronic Lipopolysaccharide Exposure Causes AD-Like Pathology in Male Mice With Intact Blood-Brain Barrier. | Eid F et al. | β | 2025 | β |
| Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEΞ΅4/Ξ΅4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial. | Abushakra S et al. | β | 2025 | β |
| Clinical Significance of APOE4 Genotyping: Potential for Personalized Therapy and Early Diagnosis of Alzheimer's Disease. | RajiΔ Bumber J et al. | β | 2025 | β |
| Common genetic variation in the APOE gene and risk of cancer: a systematic review and meta-analysis. | Barakji YA et al. | β | 2025 | β |
| Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia. | Ronnacker J et al. | β | 2025 | β |
| Comparison of Cognitive Deterioration Between Propofol and Remimazolam Anesthesia in ApoE4 Knock-In Mouse Model. | Kim JH et al. | β | 2025 | β |
| Complex genetic interactions affect susceptibility to Alzheimer's disease risk in the BIN1 and MS4A6A loci. | Nazarian A et al. | β | 2025 | β |
| Computational prediction of high-risk non-synonymous SNPs in human ApoE and their structural impact on amyloid-Ξ² interaction in Alzheimer's disease pathogenesis. | Hossain MM et al. | β | 2025 | β |
| Conformational features of guinea pig apolipoprotein E offer insights into functioning of human apolipoprotein E. | Reddick I et al. | β | 2025 | β |
| Connecting the Dots: Gender, Sexuality, and Societal Influences on Cognitive Aging and Alzheimer's Disease. | Verma S et al. | β | 2025 | β |
| Correlation of peripheral olfactomedin 1 with Alzheimer's disease and cognitive functions. | Wei C et al. | β | 2025 | β |
| Country-level incidence of Alzheimer disease and related dementias is associated with increased omega-6-PUFA consumption. | Ciesielski TH et al. | β | 2025 | β |
| CSF Ξ±-synuclein aggregation is associated with APOE Ξ΅4 and progressive cognitive decline in Alzheimer's disease. | Qiang Q et al. | β | 2025 | β |
| Decoding molecular mechanisms: brain aging and Alzheimer's disease. | Hayat M et al. | β | 2025 | β |
| Differential Effects of AΞ² Peptides on the Plasmin-Dependent Degradation of ApoE3 and ApoE4. | Kemeh MM et al. | β | 2025 | β |
| Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer's disease. | Campagna J et al. | β | 2025 | β |
| Discovery of Isobavachin, a Natural Flavonoid, as an Apolipoprotein E4 (ApoE4) Structure Corrector for Alzheimer's Disease. | Patil SP et al. | β | 2025 | β |
| Discovery of small molecules from natural compound databases as potent retinoid X alpha receptor agonists to treat Alzheimer's disease. | Rahimpour A et al. | β | 2025 | β |
| Disease-associated microglia in neurodegenerative diseases: Friend or foe? | Cheng YH et al. | β | 2025 | β |
| Disease-disease interactions: molecular links of neurodegenerative diseases with cancer, viral infections, and type 2 diabetes. | Lin Y et al. | β | 2025 | β |
| Distinct Characteristics of Suspected Non-Alzheimer Pathophysiology in Relation to Cognitive Status and Cerebrovascular Burden. | Chun MY et al. | β | 2025 | β |
| Dual single nucleotide polymorphisms typing of apolipoprotein E gene based on double restriction endonuclease with lambda exonuclease and triple helix molecular switch assistance. | Lin G et al. | β | 2025 | β |
| DYNAMIC PREDICTION WITH MULTIVARIATE LONGITUDINAL OUTCOMES AND LONGITUDINAL MAGNETIC RESONANCE IMAGING DATA. | Zou H et al. | β | 2025 | β |
| Effects of cranial X-ray irradiation in Presymptomatic 3Β ΓΒ Tg-AD mice. | Cheng W et al. | β | 2025 | β |
| Efficacy and Safety of Exogenous Ketones in People with Mild Neurocognitive Disorder and Alzheimer's Disease: A Systematic Literature Review. | Krolak-Salmon P et al. | β | 2025 | β |
| Emerging roles of astrocytes in hippocampal circuitry and behavior. | Squires A et al. | β | 2025 | β |
| Endothelial progenitor cells and cerebral small vessel disease in <i>APOE4</i> carriers. | Kapoor A et al. | β | 2025 | β |
| Experimental modeling of Alzheimer's disease: Translational lessons from cross-taxon analyses. | Yenkoyan KB et al. | β | 2025 | β |
| Exploring precision medicine by utilizing individual genetic information for the management of Alzheimer's disease. | Kanda A et al. | β | 2025 | β |
| Exploring the impact of APOE Ι4 on functional connectivity in Alzheimer's disease across cognitive impairment levels. | Dong K et al. | β | 2025 | β |
| Exploring the molecular characterization of PANoptosis-related genes with features of immune dysregulation in Alzheimer's disease based on bulk and single-nuclei RNA sequencing. | Liu H et al. | β | 2025 | β |
| Factors involved in human healthy aging: insights from longevity individuals. | Yin FQ et al. | β | 2025 | β |
| Factors related to blood-based biomarkers for neurodegenerative diseases and their intergenerational associations in the Young Finns Study: a cohort study. | Heiskanen MA et al. | β | 2025 | β |
| Focused ultrasound-mediated APOE4 knockdown in mouse brain. | Zheng K et al. | β | 2025 | β |
| Fueling the brain - the role of apolipoprotein E in brain energy metabolism and its implications for Alzheimer's disease. | Budny V et al. | β | 2025 | β |
| Gas Chromatography-Mass Spectrometry Profiling of Crateva magna Leaf Lipophilic Extract and Evaluation of Its Anti-Alzheimer and Cytotoxic Properties. | Talaat AN et al. | β | 2025 | β |
| Gender differences in cognitive benefits of meeting physical activity guidelines in older Chinese adults. | Li W et al. | β | 2025 | β |
| Gender-Specific Next-Generation Sequencing Reveals First Allelic Variation Patterns in Dementia Risk Among Bangladeshis: The CARED Study. | Ranjan R et al. | β | 2025 | β |
| Genetic PrΞΏpensity for Different Aspects of Dementia Pathology and Cognitive Decline in a Community Elderly Population. | Sampatakakis SN et al. | β | 2025 | β |
| Genetics impact risk of Alzheimer's disease through mechanisms modulating structural brain morphology in late life. | Korologou-Linden R et al. | β | 2025 | β |
| Genetic testing of common and rare variants in dementia patients from a memory clinic : Dementia-related genetic testing in memory clinic. | de Rojas I et al. | β | 2025 | β |
| Genetic variation in the Nr1d1 transcription factor binding site shapes metabolism-related protein networks associated with cognitive resilience in an Alzheimer's disease mouse reference panel. | Chen Y et al. | β | 2025 | β |
| Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease. | Hou X et al. | β | 2025 | β |
| Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B. | Godrich D et al. | β | 2025 | β |
| Glia in Neurodegenerative Disease. | Crowley G et al. | β | 2025 | β |
| Glymphatic and meningeal lymphatic dysfunction in Alzheimer's disease: Mechanisms and therapeutic perspectives. | Ding J et al. | β | 2025 | β |
| Glymphatic system and psychiatric disorders: need for a new paradigm? | Barlattani T et al. | β | 2025 | β |
| Heterozygosity in NPC may be associated with neurologic and systemic phenotypes. | BrΓ©movΓ -Ertl T et al. | β | 2025 | β |
| High-density lipoprotein cholesterol and nuclear factor I A in type 2 diabetes and mild cognitive impairment: biomarkers and mechanistic insights. | Zhao J et al. | β | 2025 | β |
| Higher CSF sTREM2 attenuates APOE Ξ΅4-related risk for amyloid pathology in cognitively intact adults: The CABLE study. | Wang YC et al. | β | 2025 | β |
| Hippocampal tau distribution in primary age-related tauopathy: The Vantaa 85+ Study. | Savola S et al. | β | 2025 | β |
| Human herpes viruses are associated with steeper age-dependent increases of serum biomarkers for dementia in cognitively unimpaired women. | James LM et al. | β | 2025 | β |
| Human iPSC-derived APOE4/4 AlzheimerΒ΄s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support. | Caceres-Palomo L et al. | β | 2025 | β |
| HYPOTHESIS: Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimer's disease in humans. | Ramsden CE et al. | β | 2025 | β |
| Identification of shared mechanisms between Alzheimer's disease and atherosclerosis by integrated bioinformatics analysis. | Wang J et al. | β | 2025 | β |
| Identifying Alzheimer's disease genes in apolipoprotein E<sup>-/-</sup> mice brains with confirmed <i>Porphyromonas gingivalis</i> entry. | Singhrao SK et al. | β | 2025 | β |
| Identifying the quantity profiles of amyloid signature proteins in different types of renal amyloidosis. | Wang S et al. | β | 2025 | β |
| Immune system-associated genes in patients with Alzheimer's disease. | Yao R et al. | β | 2025 | β |
| Impact of APOE4-related dementia risk in underrepresented groups from the All of Us research program. | Ghisays V et al. | β | 2025 | β |
| Impact of <i>APOE</i>, <i>Klotho,</i> and sex on cognitive decline with aging. | Shibata K et al. | β | 2025 | β |
| Impaired MAPT/tau-secretory lysosomes are linked to cognitive vulnerability in Alzheimer patients. | Sharma P et al. | β | 2025 | β |
| Incretin Hormones GLP-1 and GIP Normalize Energy Utilization and Reduce Inflammation in the Brain in Alzheimer's Disease and Parkinson's Disease: From Repurposed GLP-1 Receptor Agonists to Novel Dual GLP-1/GIP Receptor Agonists as Potential Disease-Modifying Therapies. | HΓΆlscher C | β | 2025 | β |
| Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype. | HellΓ©n M et al. | β | 2025 | β |
| Influence of age and sex on presymptomatic phases of neurodegenerative diseases: Focus on multiple sclerosis and Alzheimer's disease. | Zeydan B et al. | β | 2025 | β |
| Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study. | Lindblad C et al. | β | 2025 | β |
| Inhibition of Bone Morphogenetic Protein Signaling Prevents Tau Pathology in iPSC Derived Neurons and PS19 Mice. | Affaneh A et al. | β | 2025 | β |
| Innate Immune Mechanisms in the Central Nervous System. | Shastri A et al. | β | 2025 | β |
| Integrated genomic analysis and CRISPRi implicates <i>EGFR</i> in Alzheimer's disease risk. | Leung YY et al. | β | 2025 | β |
| Integrative analysis of cerebrospinal fluid biomarkers, metabolomics, and polygenic risk reveals novel metabolite associations with Alzheimer's disease. | Francia M et al. | β | 2025 | β |
| Integrative bioinformatics analysis of APOE variants in Alzheimer's disease and clinical therapeutics. | Srivastava K et al. | β | 2025 | β |
| Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel. | Greda AK et al. | β | 2025 | β |
| Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease. | Liao W et al. | β | 2025 | β |
| iPSC-derived neural organoids in dementia research: Recent advances and future directions. | Shima S et al. | β | 2025 | β |
| Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. | Thorwald MA et al. | β | 2025 | β |
| Italian intersocietal recommendations for restructuring the diagnostic-therapeutic pathway for the implementation and appropriate use of anti-amyloid monoclonal antibodies in Alzheimer's disease. | Benussi A et al. | β | 2025 | β |
| Key biomarkers in Alzheimer's disease: Insights for diagnosis and treatment strategies. | Jamal R et al. | β | 2025 | β |
| Kinematic correlates of early speech motor changes in cognitively intact APOE-Ξ΅4 carriers: a preliminary study using a color-word interference task. | Dadgostar M et al. | β | 2025 | β |
| Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors. | Barros AGA et al. | β | 2025 | β |
| Life Purpose Lowers Risk for Cognitive Impairment in a United States Population-Based Cohort. | Howard NC et al. | β | 2025 | β |
| Lifestyle, genetic risk, plasma pTau217, and incident cognitive impairment in WRAP. | Studer RL et al. | β | 2025 | β |
| Linkage and association of preserved cognitive function in the midwestern Amish at a higher genetic risk of Alzheimer's disease. | Dorfsman DA et al. | β | 2025 | β |
| Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO. | Puerta R et al. | β | 2025 | β |
| Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in <i>Caenorhabditis elegans</i>. | Tortajada-PΓ©rez J et al. | β | 2025 | β |
| LRP1 at the crossroads of AΞ² clearance and therapeutic targeting in Alzheimer's disease. | Deng Y et al. | β | 2025 | β |
| <i>APOE4-APP</i> interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer's disease. | Guo L et al. | β | 2025 | β |
| <i>APOE</i> Ξ΅4 influences the dynamic functional connectivity variability and cognitive performance in Alzheimer's disease. | Gong C et al. | β | 2025 | β |
| <i>In Vivo</i> Metabolic Labeling with an Isoprenoid Probe Reveals APOE Allele-Specific Differences in the Prenylome. | Petre AM et al. | β | 2025 | β |
| Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction. | Krogsaeter EK et al. | β | 2025 | β |
| Machine learning uncovers novel sex-specific dementia biomarkers linked to autism and eye diseases. | Khan A et al. | β | 2025 | β |
| Mechanisms of high-density lipoprotein in regulating blood-brain barrier function: insights and implications. | Zhu P et al. | β | 2025 | β |
| Mechanistic Insights and Translational Therapeutics of Neurovascular Unit Dysregulation in Vascular Cognitive Impairment. | Lin LS et al. | β | 2025 | β |
| Medical risk factors, ApoE haplotype, and Alzheimer's disease: a large-scale analysis. | Elias U et al. | β | 2025 | β |
| Meningeal lymphatic drainage: novel insights into central nervous system disease. | Zhang Q et al. | β | 2025 | β |
| Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer's disease model. | Rao A et al. | β | 2025 | β |
| Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4. | Nolt GL et al. | β | 2025 | β |
| Microglial mechanisms drive amyloid-Ξ² clearance in immunized patients with Alzheimer's disease. | van Olst L et al. | β | 2025 | β |
| Microglia-to-neuron signaling links <i>APOE4</i> and inflammation to enhanced neuronal lipid metabolism and network activity. | Verduzco Espinoza AP et al. | β | 2025 | β |
| Milestone Review: The History of Molecular Genetics Analysis of Alzheimer's Disease. | Hardy J | β | 2025 | β |
| Mirodenafil improves cognitive function by reducing microglial activation and blood-brain barrier permeability in ApoE4 KI mice. | Park Y et al. | β | 2025 | β |
| Mitochondrial Dysfunction Correlates with Brain Amyloid Binding, Memory, and Executive Function in Down Syndrome: Implications for Alzheimer's Disease in Down Syndrome. | Beresford-Webb JA et al. | β | 2025 | β |
| Moderating effect of APOE Ξ΅4 on the association of sleep disturbance and amyloid-Ξ² pathology among cognitively normal older adults. | Feng S et al. | β | 2025 | β |
| Move to Remember: The Role of Physical Activity and Exercise in Preserving and Enhancing Cognitive Function in Aging-A Narrative Review. | MartΓn-RodrΓguez A et al. | β | 2025 | β |
| MRI Distance Measures as a Predictor of Subsequent Clinical Status During the Preclinical Phase of Alzheimer's Disease and Related Disorders. | Zhang X et al. | β | 2025 | β |
| MtDNA-depleted neuronal cell transcriptomes reveal Alzheimer's disease-related changes. | Menta BW et al. | β | 2025 | β |
| Multi-functional role of apolipoprotein E in neurodegenerative diseases. | Islam S et al. | β | 2025 | β |
| Multi-omics analysis for identifying cell-type-specific and bulk-level druggable targets in Alzheimer's disease. | Liu S et al. | β | 2025 | β |
| Navigation Between Alzheimer's Disease (AD) and Its Various Pathophysiological Trajectories: The Pathogenic Link to Neuroimmunology-Genetics and Neuroinflammation. | Bowirrat A et al. | β | 2025 | β |
| Network biomarkers of Alzheimer's disease risk derived from joint volume and texture covariance patterns in mouse models. | Bridgeford EW et al. | β | 2025 | β |
| Neurodegeneration and aging: pathophysiology, diagnosis, and therapeutic targets. | Thakur A et al. | β | 2025 | β |
| Neuroimmune Dysregulation and AI-Driven Therapeutic Strategies in Alzheimer's Disease. | Ghosh S et al. | β | 2025 | β |
| Neurological and Olfactory Disturbances After General Anesthesia. | Maniaci A et al. | β | 2025 | β |
| Not your mother's hormone therapy: Highly selective estrogen receptor beta agonists as next-generation therapies for menopausal symptom relief. | Frick KM et al. | β | 2025 | β |
| Opportunities and challenges of local ancestry in genetic association analyses. | Sun Q et al. | β | 2025 | β |
| Optimized prime editing of the Alzheimer's disease-associated APOE4 mutation. | Rottner AK et al. | β | 2025 | β |
| Path integration impairments reveal early cognitive changes in subjective cognitive decline. | Segen V et al. | β | 2025 | β |
| Pathways underlying selective neuronal vulnerability in Alzheimer's disease: Contrasting the vulnerable locus coeruleus to the resilient substantia nigra. | Ehrenberg AJ et al. | β | 2025 | β |
| Phenome-wide association of APOE alleles in the All of Us Research Program. | Khajouei E et al. | β | 2025 | β |
| Plasma biomarker trajectories: Impact of AD genetic risk and clinical progression. | Pettigrew C et al. | β | 2025 | β |
| Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer's disease. | Guo MH et al. | β | 2025 | β |
| PolyGR-containing aggregates link with pathology and clinical features of Alzheimer's disease. | Phuong HT et al. | β | 2025 | β |
| Population intervention models of racial ethnic disparities in cognitive outcomes from cardiometabolic risk factors - HABS-HD. | Hayes CA et al. | β | 2025 | β |
| Potential Genetic Intersections Between ADHD and Alzheimer's Disease: A Systematic Review. | Borgonovo R et al. | β | 2025 | β |
| Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease. | Shen Y et al. | β | 2025 | β |
| Preclinical Alzheimer's disease shows alterations in circulating neuronal-derived extracellular vesicle microRNAs in a multiethnic cohort. | Reho P et al. | β | 2025 | β |
| Predicting Mutation-Disease Associations Through Protein Interactions Via Deep Learning. | Li X et al. | β | 2025 | β |
| Primary age-related tauopathy. | Richardson TE et al. | β | 2025 | β |
| Promising clinical tools for specific Alzheimer disease diagnosis from plasma pTau217 and ApoE genotype in a cognitive disorder unit. | Γlvarez-SΓ‘nchez L et al. | β | 2025 | β |
| Proteome profiling of cerebrospinal fluid using machine learning shows a unique protein signature associated with APOE4 genotype. | Shvetcov A et al. | β | 2025 | β |
| Proteostasis disruption and lipid dyshomeostasis in neurodegeneration: exploring common druggable targets across sporadic and monogenic disorders. | Pereira Sena P et al. | β | 2025 | β |
| Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP): A global effort to identify genetic factors in Alzheimer's disease. | Akinyemi R et al. | β | 2025 | β |
| Region-Based Analysis with Functional Annotation Identifies Genes Associated with Cognitive Function in South Asians from India. | Abu-Amara H et al. | β | 2025 | β |
| Regulation of glial ApoE secretion by the mevalonate pathway is independent of ApoE isoform. | Milstein JL et al. | β | 2025 | β |
| Reply: PART and amyloid cascade hypotheses are alive and well (but are not so simple). | Braak H et al. | β | 2025 | β |
| Retinal manifestations and their diagnostic significance in Alzheimer's disease. | Abhyankar SD et al. | β | 2025 | β |
| RETRACTED: Idea Density and Grammatical Complexity as Neurocognitive Markers. | Iacono D et al. | β | 2025 | β |
| Review of the evidence on the influence of Wi-Fi 2.4β―GHz radiation on oxidative stress and its possible relationship with Alzheimer's disease. | LavΓ‘n D et al. | β | 2025 | β |
| Roles of TREM2 in Alzheimer's disease. | Qi X et al. | β | 2025 | β |
| Rotation errors in path integration are associated with Alzheimer's disease tau pathology: a cross-sectional study. | Colmant L et al. | β | 2025 | β |
| Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment. | Lee BC et al. | β | 2025 | β |
| Sequence and trajectory of early Alzheimer's disease-related tau inclusions in the hippocampal formation of cases without amyloid-Ξ² deposits. | Braak H et al. | β | 2025 | β |
| Sequential Proteomic Analysis Reveals the Key APOE4-Induced Pathological and Molecular Features at the Presymptomatic Stage in Alzheimer's Disease Mice. | Wei P et al. | β | 2025 | β |
| Serum proteomics reveals early biomarkers of Alzheimer's disease: The dual role of APOE-Ξ΅4. | Ma YN et al. | β | 2025 | β |
| Sex and APOE Ξ΅4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease. | Peterson A et al. | β | 2025 | β |
| Sex differences in age-associated neurological diseases-A roadmap for reliable and high-yield research. | Bonkhoff AK et al. | β | 2025 | β |
| Sex differences in <i>in vivo</i> biomarkers of neurodegenerative dementia. | Mak E et al. | β | 2025 | β |
| Sex-specific brain atrophy patterns associated with the motoric cognitive risk syndrome. | Blumen HM et al. | β | 2025 | β |
| Sex variation in the relationship between <i>APOE</i> Ξ΅4, cognitive decline, and dementia. | Kerr EM et al. | β | 2025 | β |
| Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD). | Lizama BN et al. | β | 2025 | β |
| Spatial navigation deficits in early Alzheimer's disease: the role of biomarkers and APOE genotype. | LaczΓ³ M et al. | β | 2025 | β |
| Statins, cholesterol and cognition at the time of Alzheimer's disease diagnosis: A cross-sectional study from the Swedish registry for cognitive/dementia disorders. | Petek B et al. | β | 2025 | β |
| Structural Analysis of Missense Mutations on the Stability of APOE3 and APOE4. | Anthony M et al. | β | 2025 | β |
| Structural insights into human ABCA7-mediated lipid transport. | Fang SC et al. | β | 2025 | β |
| Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. | Jiang WI et al. | β | 2025 | β |
| Targeting Amyloid Pathology in Early Alzheimer's: The Promise of Donanemab-Azbt. | Khartabil N et al. | β | 2025 | β |
| Targeting mitophagy in neurodegenerative diseases. | Antico O et al. | β | 2025 | β |
| Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer's Disease Phenotype in APP/PS1 Transgenic Mice. | Querfurth HW et al. | β | 2025 | β |
| Tg-SwDI transgenic mice: A suitable model for Alzheimer's disease and cerebral amyloid angiopathy basic research and preclinical studies. | Rodriguez-Lopez A et al. | β | 2025 | β |
| The Amyloid Cascade Hypothesis: A Conclusion in Search of Support. | Castellani RJ et al. | β | 2025 | β |
| The association between SLIT2 in human vitreous humor and plasma and neurocognitive test scores. | Shoushtari SI et al. | β | 2025 | β |
| The continued promise of genomic technologies and software in neurogenetics. | Xu IRL et al. | β | 2025 | β |
| The effect of APOE4 on Alzheimer's plasma biomarkers among Mexican Americans in the HABS-HD cohort. | Contreras JA et al. | β | 2025 | β |
| The effect of C-reactive protein and interleukin-3 on mild cognitive impairment with <i>APOE</i> Ι4. | Yang X et al. | β | 2025 | β |
| The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis. | Spencer FSE et al. | β | 2025 | β |
| The Eye as a Window to Brain Health: Can Retinal Imaging and AI Modeling Predict Alzheimer's Disease? | Awodiya E | β | 2025 | β |
| The glymphatic system as a therapeutic target: TMS-induced modulation in older adults. | Sundman MH et al. | β | 2025 | β |
| The history of Down syndrome-associated Alzheimer's disease; past, present, and future. | Maure-Blesa L et al. | β | 2025 | β |
| The impact of apolipoprotein E, type β4 allele on Alzheimer's disease pathological biomarkers: a comprehensive post-mortem pilot-analysis. | Wan Z et al. | β | 2025 | β |
| The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress. | Cacabelos R et al. | β | 2025 | β |
| The impact of rare genetic variants on Alzheimer disease. | De Deyn L et al. | β | 2025 | β |
| The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases. | Feringa FM et al. | β | 2025 | β |
| The Oral-Brain Axis in Alzheimer's Disease: From Microbial Dysbiosis to Neurodegeneration. | Felicetti A et al. | β | 2025 | β |
| The relationship between kidney health and neurodegenerative diseases. | Zuo M et al. | β | 2025 | β |
| The relationship between neuropsychiatric dimensions and markers of Parkinson's disease risk in the UK Biobank. | Attaallah B et al. | β | 2025 | β |
| The rhythm of decline: Circadian disruption in neurodegeneration. | Singh J et al. | β | 2025 | β |
| The Risk of Alzheimer Disease in APOE4 Homozygotes. | Reiman EM et al. | β | 2025 | β |
| The role of microbiota modulation in preventing Alzheimer's disease- a review. | StrzΔpa A et al. | β | 2025 | β |
| The role of quantitative EEG biomarkers in Alzheimer's disease and mild cognitive impairment: applications and insights. | Yuan Y et al. | β | 2025 | β |
| The Role of the Neural Exposome as a Novel Strategy to Identify and Mitigate Health Inequities in Alzheimer's Disease and Related Dementias. | Granov R et al. | β | 2025 | β |
| The Spectrum of Genetic Risk in Alzheimer Disease. | Karagas N et al. | β | 2025 | β |
| The VA Million Veteran Program, Alzheimer's disease, and genetics: Important steps forward but many steps still to go on the march to control dementia and Alzheimer's disease. | Ashford JW | β | 2025 | β |
| Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer's disease. | Chen J et al. | β | 2025 | β |
| Traumatic Brain Injury and Chronic Traumatic Encephalopathy: Not Only Trigger for Neurodegeneration but Also for Cerebral Amyloid Angiopathy? | Zedde M et al. | β | 2025 | β |
| TREM2-apoE3 interactions and Alzheimer's disease: Molecular and structural insights and effects of TREM2 R47H and apoE4 variants. | Greer RA et al. | β | 2025 | β |
| Trends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease. | Kantor B et al. | β | 2025 | β |
| TTC7A missense variants in intestinal disease can be classified by molecular and cellular phenotypes. | Shojaei Jeshvaghani Z et al. | β | 2025 | β |
| Uncovering dark mass in population proteomics: Pan-analysis of single amino acid polymorphism relevant to cognition and aging. | Gao X et al. | β | 2025 | β |
| Unraveling APOE4's Role in Alzheimer's Disease: Pathologies and Therapeutic Strategies. | Tripathi S et al. | β | 2025 | β |
| Unraveling APOE4: The dual role in CNS and peripheral inflammation in Alzheimer's disease. | Li X et al. | β | 2025 | β |
| Unraveling the mystery of citrate transporters in Alzheimer's disease: An updated review. | Mukherjee AG et al. | β | 2025 | β |
| Vision and convolutional transformers for Alzheimer's disease diagnosis: a systematic review of architectures, multimodal fusion and critical gaps. | Afifi I et al. | β | 2025 | β |
| Vitamin D deficiency may accelerate cognitive decline in female apolipoprotein E Ξ΅4 non-carriers. | Kim J et al. | β | 2025 | β |
| Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change. | Vidal-PiΓ±eiro D et al. | β | 2025 | β |
| Ξ²-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity. | Holmes BB et al. | β | 2025 | β |
| $$ {\ell}_1 $$ -Penalized Multinomial Regression: Estimation, Inference, and Prediction, With an Application to Risk Factor Identification for Different Dementia Subtypes. | Tian Y et al. | β | 2024 | β |
| 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. | Martin SS et al. | β | 2024 | β |
| AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in Alzheimer's disease mice. | GΓΌnaydin C et al. | β | 2024 | β |
| A Bayesian semi-parametric model for learning biomarker trajectories and changepoints in the preclinical phase of Alzheimer's disease. | Wang K et al. | β | 2024 | β |
| A Brief History of the Progress in Our Understanding of Genetics and Lifestyle, Especially Diet, in the Risk of Alzheimer's Disease. | Grant WB | β | 2024 | β |
| A case for seeking sex-specific treatments in Alzheimer's disease. | Lynch MA | β | 2024 | β |
| A circadian clock regulates the blood-brain barrier across phylogeny. | Avila A et al. | β | 2024 | β |
| A comparative study of structural variant calling in WGS from Alzheimer's disease families. | Malamon JS et al. | β | 2024 | β |
| A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank. | Heise V et al. | β | 2024 | β |
| Actigraphy Estimated Sleep Moderates the Relationship between Physical Activity and Cognition in Older Adults. | Callow DD et al. | β | 2024 | β |
| Acute Kidney Injury, Systemic Inflammation, and Long-Term Cognitive Function: ASSESS-AKI. | Bhatraju PK et al. | β | 2024 | β |
| Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference. | Kloske CM et al. | β | 2024 | β |
| Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City. | Sosa AL et al. | β | 2024 | β |
| Advances and Challenges in Gene Therapy for Alzheimer's Disease. | Morroni F et al. | β | 2024 | β |
| African Ancestry Individuals with Higher Educational Attainment Are Resilient to Alzheimer's Disease Measured by pTau181. | Rajabli F et al. | β | 2024 | β |
| Age, sex, and APOE gene-specific associations between dynapenic obesity and dementia in a large cohort. | Yao Z et al. | β | 2024 | β |
| Alzheimer's disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles. | Hosseininasab SSM et al. | β | 2024 | β |
| Alzheimer's disease genetic risk and changes in brain atrophy and white matter hyperintensities in cognitively unimpaired adults. | Soldan A et al. | β | 2024 | β |
| Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. | Carling GK et al. | β | 2024 | β |
| Alzheimer's disease manifests abnormal sphingolipid metabolism. | Uranbileg B et al. | β | 2024 | β |
| Alzheimer's Disease Neuropathological Change in Aged Non-Primate Mammals. | Ferrer I | β | 2024 | β |
| Alzheimer's Disease-Related Epigenetic Changes: Novel Therapeutic Targets. | Paniri A et al. | β | 2024 | β |
| Amyloid-Ξ² and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer's Disease. | Pradeepkiran JA et al. | β | 2024 | β |
| Amyloid-Ξ² in Alzheimer's disease: Structure, toxicity, distribution, treatment, and prospects. | Yu Y et al. | β | 2024 | β |
| Amyloid-Ξ² prediction machine learning model using source-based morphometry across neurocognitive disorders. | Momota Y et al. | β | 2024 | β |
| Animal models of Alzheimer's disease: Current strategies and new directions. | Wang Q et al. | β | 2024 | β |
| APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease. | Jackson RJ et al. | β | 2024 | β |
| APOE4 homozygosity is a new genetic form of Alzheimer's disease. | Xu Q et al. | β | 2024 | β |
| APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease. | Fortea J et al. | β | 2024 | β |
| APOEΓBDNF Interaction and Poorer Cognitive Outcomes Among Veterans With Mild Traumatic Brain Injury: An Exploratory Study. | Ton Loy AF et al. | β | 2024 | β |
| APOE epsilon variants and composite risk of dementia, disability, and death in the health and retirement study. | Clocchiatti-Tuozzo S et al. | β | 2024 | β |
| APOE from astrocytes restores Alzheimer's AΞ²-pathology and DAM-like responses in APOE deficient microglia. | Preman P et al. | β | 2024 | β |
| APOE genotype, hippocampal volume, and cognitive reserve predict improvement by cognitive training in older adults without dementia: a randomized controlled trial. | Montejo Carrasco P et al. | β | 2024 | β |
| APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response. | Panitch R et al. | β | 2024 | β |
| ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9. | Ghosh S et al. | β | 2024 | β |
| ApoE: The Non-Protagonist Actor in Neurological Diseases. | Grimaldi L et al. | β | 2024 | β |
| APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size. | Windham IA et al. | β | 2024 | β |
| APOEΞ΅4 Carriers Exhibit Objective Cognitive Deficits: A Cross-Sectional Study in a Single Center Trial. | Zeng Y et al. | β | 2024 | β |
| Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging. | Peng KY et al. | β | 2024 | β |
| Apolipoprotein E Genetic Testing in a New Age of Alzheimer Disease Clinical Practice. | Ritchie M et al. | β | 2024 | β |
| Apolipoprotein E in Alzheimer's disease trajectories and the next-generation clinical care pathway. | Narasimhan S et al. | β | 2024 | β |
| Apolipoprotein E Induces Lipid Accumulation Through Dgat2 That Is Prevented with Time-Restricted Feeding in <i>Drosophila</i>. | Moraes RCM et al. | β | 2024 | β |
| Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins. | Strickland MR et al. | β | 2024 | β |
| APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in <i>APOE</i> Ξ΅4/Ξ΅4 homozygotes with early Alzheimer's disease: Trial design and baseline characteristics. | Abushakra S et al. | β | 2024 | β |
| A Simplified Proteomics LC-MRM-MS Assay for Determination of apoE Genotypes in Plasma Samples. | Qasrawi DO et al. | β | 2024 | β |
| Assessing the Impact and Cost-Effectiveness of Exposome Interventions on Alzheimer's Disease: A Review of Agent-Based Modeling and Other Data Science Methods for Causal Inference. | Liu SH et al. | β | 2024 | β |
| Assessment of circulating apoE4 levels from dried blood spot samples in a large survey setting. | Borbye-Lorenzen N et al. | β | 2024 | β |
| Association Between Small Vessel Disease and Financial Capacity: A Study Based on Cognitively Normal Older Adults. | Luo X et al. | β | 2024 | β |
| Association Between Traumatic Brain Injury and Cognitive Decline Among Middle-to-Older Aged Men in the Vietnam Era Twin Study of Aging. | Posis AIB et al. | β | 2024 | β |
| Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project. | Lee WP et al. | β | 2024 | β |
| Association of Egg Intake With Alzheimer's Dementia Risk in Older Adults: The Rush Memory and Aging Project. | Pan Y et al. | β | 2024 | β |
| Association of estimated pulse wave velocity with cognitive function in a multiethnic diverse population: The Northern Manhattan Study. | Aimagambetova B et al. | β | 2024 | β |
| Association of Heart Failure With Cognitive Decline and Development of Mild Cognitive Impairment and Dementia. | Jung M et al. | β | 2024 | β |
| Association of metabolic dysfunction with cognitive decline and Alzheimer's disease: A review of metabolomic evidence. | Amidfar M et al. | β | 2024 | β |
| Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer's disease. | Qi Q et al. | β | 2024 | β |
| Associations of combined accelerated biological aging and genetic susceptibility with incident dementia: a prospective study in the UK Biobank. | Ye Z et al. | β | 2024 | β |
| Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular Ξ±-synuclein. | Andromidas F et al. | β | 2024 | β |
| BLESS: bagged logistic regression for biomarker identification. | Gardiner K et al. | β | 2024 | β |
| Blood-Based mtDNA Quantification Indicates Population-Specific Differences Associated with Alzheimer's Disease-Related Risk. | Gorham IK et al. | β | 2024 | β |
| Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE Ξ΅4-enriched cognitively unimpaired elderly. | KoivumΓ€ki M et al. | β | 2024 | β |
| Boosting peripheral immunity to fight neurodegeneration in the brain. | Schwartz M et al. | β | 2024 | β |
| Brain aging and Alzheimer's disease, a perspective from non-human primates. | Isidro F | β | 2024 | β |
| Brain network fingerprints of Alzheimer's disease risk factors in mouse models with humanized APOE alleles. | Winter S et al. | β | 2024 | β |
| Can integration of Alzheimer's plasma biomarkers with MRI, cardiovascular, genetics, and lifestyle measures improve cognition prediction? | Gebre RK et al. | β | 2024 | β |
| Cell type-specific roles of APOE4 in Alzheimer disease. | Blumenfeld J et al. | β | 2024 | β |
| Cerebral microvascular changes in healthy carriers of the APOE-Ι4 Alzheimer's disease risk gene. | Aamand R et al. | β | 2024 | β |
| Cerebrospinal fluid biomarker profiling of diverse pathophysiological domains in Alzheimer's disease. | Trombetta BA et al. | β | 2024 | β |
| Changes in expression of VGF, SPECC1L, HLA-DRA and RANBP3L act with APOE E4 to alter risk for late onset Alzheimer's disease. | Branciamore S et al. | β | 2024 | β |
| Characterizing the pathogenicity of genetic variants: the consequences of context. | Ciesielski TH et al. | β | 2024 | β |
| Cholesterol Metabolism in Neurodegenerative Diseases. | He K et al. | β | 2024 | β |
| Circulating apoE4 protein levels from dried blood spots predict cognitive function in a large population-based survey setting. | Deza-Lougovski YI et al. | β | 2024 | β |
| Clinician's perspectives on gene therapy for Alzheimer's disease: A qualitative study. | Kelemen L et al. | β | 2024 | β |
| Cluster Analysis of Cortical Amyloid Burden for Identifying Imaging-driven Subtypes in Mild Cognitive Impairment. | Wu R et al. | β | 2024 | β |
| Co-aggregation with Apolipoprotein E modulates the function of Amyloid-Ξ² in Alzheimer's disease. | Xia Z et al. | β | 2024 | β |
| Cognitive Decline in Ageing and Disease: Risk factors, Genetics and Treatments. | Colita E et al. | β | 2024 | β |
| Cognitive Dysfunction and Exercise: From Epigenetic to Genetic Molecular Mechanisms. | Zhang R et al. | β | 2024 | β |
| Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice. | Wieg L et al. | β | 2024 | β |
| Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET. | Tato-FernΓ‘ndez C et al. | β | 2024 | β |
| Cognitive synaptopathy: synaptic and dendritic spine dysfunction in age-related cognitive disorders. | Barrantes FJ | β | 2024 | β |
| Contrasting association pattern of plasma low-density lipoprotein with white matter integrity in APOE4 carriers versus non-carriers. | Ye Z et al. | β | 2024 | β |
| Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History. | Bermejo-Pareja F et al. | β | 2024 | β |
| CoQ<sub>10</sub> and Mitochondrial Dysfunction in Alzheimer's Disease. | FiΕ‘ar Z et al. | β | 2024 | β |
| Correlation analysis of peripheral platelet markers and disease phenotypes in Alzheimer's disease. | Fu J et al. | β | 2024 | β |
| COVID-19 and the impact on Alzheimer's disease pathology. | Furman S et al. | β | 2024 | β |
| CRISPR/Cas9 system and its applications in nervous system diseases. | Jiang H et al. | β | 2024 | β |
| Current insights into apolipoprotein E and the immune response in Alzheimer's disease. | Lin PB et al. | β | 2024 | β |
| Definition of a Threshold for the Plasma AΞ²42/AΞ²40 Ratio Measured by Single-Molecule Array to Predict the Amyloid Status of Individuals without Dementia. | Colmant L et al. | β | 2024 | β |
| Deletion of miR-33, a regulator of the ABCA1-APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice. | Tate M et al. | β | 2024 | β |
| Diabetes mellitus and risk of incident dementia in APOE Ι4 carriers: an updated meta-analysis. | Rashtchian A et al. | β | 2024 | β |
| Differences in Alzheimer's Disease-Related Pathology Profiles Across Apolipoprotein Groups. | Morrison C et al. | β | 2024 | β |
| Disease- and stage-specific alterations of the oral and fecal microbiota in Alzheimer's disease. | Troci A et al. | β | 2024 | β |
| Do microbes play a role in Alzheimer's disease? | Williams ZAP et al. | β | 2024 | β |
| Drug Development for Alzheimer's and Parkinson's Disease: Where Do We Go Now? | Sequeira L et al. | β | 2024 | β |
| Early CA2 Tau Inclusions Do Not Distinguish an Age-Related Tauopathy from Early Alzheimer's Disease. | Del Tredici K et al. | β | 2024 | β |
| Effect and Mechanism of Rapamycin on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-analysis of Preclinical Studies. | Cai J et al. | β | 2024 | β |
| Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease. | Hey JA et al. | β | 2024 | β |
| Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE Ξ΅4 homozygotes. | Riviere ME et al. | β | 2024 | β |
| Evaluation of the NIH Toolbox Odor Identification Test across normal cognition,Β amnestic mild cognitive impairment, and dementia due to Alzheimer's disease. | Echevarria-Cooper SL et al. | β | 2024 | β |
| Evidence that Alzheimer's Disease Is a Disease of Competitive Synaptic Plasticity Gone Awry. | Huang Z | β | 2024 | β |
| Exploring the Genetic Heterogeneity of Alzheimer's Disease: Evidence for Genetic Subtypes. | Elman JA et al. | β | 2024 | β |
| Exploring the pathogenesis and key genes associated of acute myocardial infarction complicated with Alzheimer's disease. | Liu C et al. | β | 2024 | β |
| Exploring the role of apolipoprotein E gene promoter polymorphisms in susceptibility to normal-tension glaucoma in a Korean population. | Park YJ et al. | β | 2024 | β |
| Exploring the role of mitochondrial uncoupling protein 4 in brain metabolism: implications for Alzheimer's disease. | Crivelli SM et al. | β | 2024 | β |
| Florbetapir PET-assessed demyelination is associated with faster tau accumulation in an APOE Ξ΅4-dependent manner. | Rubinski A et al. | β | 2024 | β |
| From early methods for DNA diagnostics to genomes and epigenomes at high resolution during four decades - a personal perspective. | SyvΓ€nen AC | β | 2024 | β |
| From Plaques to Pathways in Alzheimer's Disease: The Mitochondrial-Neurovascular-Metabolic Hypothesis. | Kazemeini S et al. | β | 2024 | β |
| Fueling Alzheimer's Disease: Where Does Immunometabolism Stand? | Correia SC et al. | β | 2024 | β |
| Fueling neurodegeneration: metabolic insights into microglia functions. | Sadeghdoust M et al. | β | 2024 | β |
| Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions. | Garcia-Cordero I et al. | β | 2024 | β |
| Generation of induced pluripotent stem cell line (XWHNi003-A) from a female with APOE gene mutation. | Gong J et al. | β | 2024 | β |
| Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center. | Fernandez MV et al. | β | 2024 | β |
| Genetic biomarkers of cognitive impairment and dementia of potential interest in CKD patients. | Zoccali C et al. | β | 2024 | β |
| Genome-wide association studies identify novel loci in rapidly progressive Alzheimer's disease. | Wang P et al. | β | 2024 | β |
| Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank. | Alcalde-Herraiz M et al. | β | 2024 | β |
| Gut Microbiome Changes in Patients With Idiopathic Normal Pressure Hydrocephalus. | Brandt E et al. | β | 2024 | β |
| Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-Ξ² Pathology in APP/PS1 Mice. | Lapeyre L et al. | β | 2024 | β |
| Hippocampal volumes in UK Biobank are associated with <i>APOE</i> only in older adults. | Chaloemtoem A et al. | β | 2024 | β |
| HIV-Associated Neurocognitive Disorder (HAND) and Alzheimer's Disease Pathogenesis: Future Directions for Diagnosis and Treatment. | Mustafa M et al. | β | 2024 | β |
| Human APOE4 Protects High-Fat and High-Sucrose Diet Fed Targeted Replacement Mice against Fatty Liver Disease Compared to APOE3. | Huebbe P et al. | β | 2024 | β |
| Human apolipoprotein E glycosylation and sialylation: from structure to function. | Moon HJ et al. | β | 2024 | β |
| Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology. | Miller B et al. | β | 2024 | β |
| <i>APOE</i> Ι4 exacerbates age-dependent deficits in cortical microstructure. | Mak E et al. | β | 2024 | β |
| Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease. | Chen Q et al. | β | 2024 | β |
| Identifying the earliest-occurring clinically targetable precursors of late-onset Alzheimer's disease. | Cohen BM et al. | β | 2024 | β |
| Immunological aspects of central neurodegeneration. | Niso-Santano M et al. | β | 2024 | β |
| Impact of age and apolipoprotein E Ξ΅4 status on regional white matter hyperintensity volume and cognition in healthy aging. | Van Etten EJ et al. | β | 2024 | β |
| Impact of APOE Ξ΅4 and Ξ΅2 on plasma neurofilament light chain and cognition in autosomal dominant Alzheimer's disease. | Langella S et al. | β | 2024 | β |
| Impact of Apolipoprotein E Ξ΅4 in Alzheimer's Disease: A Meta-Analysis of Voxel-Based Morphometry Studies. | Bailey M et al. | β | 2024 | β |
| Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effects. | Ghosh S et al. | β | 2024 | β |
| Induced pluripotent stem cell models as a tool to investigate and test fluid biomarkers in Alzheimer's disease and frontotemporal dementia. | McInvale JJ et al. | β | 2024 | β |
| Inflammation and DNA methylation in Alzheimer's disease: mechanisms of epigenetic remodelling by immune cell oxidants in the ageing brain. | Seddon AR et al. | β | 2024 | β |
| Inhibitory Roles of <i>Apolipoprotein E</i> Christchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models. | Murakami R et al. | β | 2024 | β |
| Integration of iPSC-Derived Microglia into Brain Organoids for Neurological Research. | Mrza MA et al. | β | 2024 | β |
| Intelligent Alzheimer's Diseases Gene Association Prediction Model Using Deep Regulatory Genomic Neural Networks. | Rohini M et al. | β | 2024 | β |
| Interactions between physical exercise, associative memory, and genetic risk for Alzheimer's disease. | Igloi K et al. | β | 2024 | β |
| Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study. | Waterink L et al. | β | 2024 | β |
| Investigating a Novel Neurodegenerative Disease Toxic Mechanism Involving Lipid Binding Specificity of Amyloid Oligomers. | Hirschbeck SS et al. | β | 2024 | β |
| Investigating the Potential Impact of Air Pollution on Alzheimer's Disease and the Utility of Multidimensional Imaging for Early Detection. | Singh S A et al. | β | 2024 | β |
| iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype. | Sullivan MA et al. | β | 2024 | β |
| Is Alzheimer disease a disease? | Korczyn AD et al. | β | 2024 | β |
| Isoform- and cell-state-specific APOE homeostasis and function. | Lindner K et al. | β | 2024 | β |
| Ketone body metabolism and cardiometabolic implications for cognitive health. | Fulghum K et al. | β | 2024 | β |
| Kinetic-thermodynamic correlation of conformational changes in ammonium complexes of a flexible naphthocage. | He S et al. | β | 2024 | β |
| Lessons from genetic studies in Alzheimer disease. | Nicolas G | β | 2024 | β |
| Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights. | Tang AS et al. | β | 2024 | β |
| Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis. | Nelson PT et al. | β | 2024 | β |
| Lipids, lipoproteins, and apolipoproteins: Associations with cognition and dementia. | Juul Rasmussen I et al. | β | 2024 | β |
| Lipophorin receptors genetically modulate neurodegeneration caused by reduction of Psn expression in the aging Drosophila brain. | Kang J et al. | β | 2024 | β |
| Lipoprotein Particles in Cerebrospinal Fluid. | Tsujita M et al. | β | 2024 | β |
| Low-Density Lipoprotein Receptor-Related Protein 1 as a Potential Therapeutic Target in Alzheimer's Disease. | Petralla S et al. | β | 2024 | β |
| Lower neurovascular coupling response despite higher cerebral blood flow at rest in apolipoprotein Ι4 positive adults. | Pearson AG et al. | β | 2024 | β |
| <i>APOE3</i> Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease. | Quiroz YT et al. | β | 2024 | β |
| Machine Learning Models of Polygenic Risk for Enhanced Prediction of Alzheimer Disease Endophenotypes. | Gunter NB et al. | β | 2024 | β |
| Machine learning quantification of Amyloid-Ξ² deposits in the temporal lobe of 131 brain bank cases. | Scalco R et al. | β | 2024 | β |
| Mass Spectrometry Imaging of Cholesterol and Oxysterols. | Griffiths WJ et al. | β | 2024 | β |
| Metabolomics profiling reveals distinct, sex-specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease. | Pandey RS et al. | β | 2024 | β |
| Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer's disease. | Sun GG et al. | β | 2024 | β |
| Midlife and late-life environmental exposures on dementia risk in the Wisconsin Longitudinal Study: The modifying effects of ApoE. | Williams VJ et al. | β | 2024 | β |
| Midlife Residential Greenness and Late-Life Cognitive Decline among Nurses' Health Study Participants. | Pescador Jimenez M et al. | β | 2024 | β |
| Missense and loss-of-function variants at GWAS loci in familial Alzheimer's disease. | Gunasekaran TI et al. | β | 2024 | β |
| Mitochondrial Dysfunction: A Key Player in Brain Aging and Diseases. | Bartman S et al. | β | 2024 | β |
| Modeling sporadic Alzheimer's disease in mice by combining Apolipoprotein E4 risk gene with environmental risk factors. | Ganesan K et al. | β | 2024 | β |
| mRNA and circRNA mislocalization to synapses are key features of Alzheimer's disease. | Smukowski SN et al. | β | 2024 | β |
| Multi-class Prediction of Cognitively Normal / Mild Cognitive Impairment / Alzheimer's Disease Status in Dementia Based on Convolutional Neural Networks with Attention Mechanism. | Yao M et al. | β | 2024 | β |
| Multifaceted roles of APOE in Alzheimer disease. | Jackson RJ et al. | β | 2024 | β |
| Multi-Omic Blood Biomarkers as Dynamic Risk Predictors in Late-Onset Alzheimer's Disease. | Bhalala OG et al. | β | 2024 | β |
| Multiple Roles of Apolipoprotein E4 in Oxidative Lipid Metabolism and Ferroptosis During the Pathogenesis of Alzheimer's Disease. | Faraji P et al. | β | 2024 | β |
| Naturalistic assessment of reaction time variability in older adults at risk for Alzheimer's disease. | Welhaf MS et al. | β | 2024 | β |
| Navigating the omics era of lipid metabolism. | Henne WM | β | 2024 | β |
| Neuronal Stem Cells from Late-Onset Alzheimer Patients Show Altered Regulation of Sirtuin 1 Depending on Apolipoprotein E Indicating Disturbed Stem Cell Plasticity. | Jung M et al. | β | 2024 | β |
| New insights in lipid metabolism: potential therapeutic targets for the treatment of Alzheimer's disease. | Cao Y et al. | β | 2024 | β |
| NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology. | Paesmans I et al. | β | 2024 | β |
| Non-canonical pathways associated to Amyloid beta and tau protein dyshomeostasis in Alzheimer's disease: A narrative review. | Maggiore A et al. | β | 2024 | β |
| Nonlipogenic ABCA1 Inducers (NLAI) for Alzheimer's Disease Validated in a Mouse Model Expressing Human <i>APOE3/APOE4</i>. | Velma GR et al. | β | 2024 | β |
| Novel Role of Pin1-Cis P-Tau-ApoE Axis in the Pathogenesis of Preeclampsia and Its Connection with Dementia. | Amabebe E et al. | β | 2024 | β |
| Nuclear SphK2/S1P signaling is a key regulator of ApoE production and AΞ² uptake in astrocytes. | Komai M et al. | β | 2024 | β |
| Odor Identification Across Time in Mutation Carriers and Non-Carriers in Autosomal-Dominant Alzheimer's Disease. | Almkvist O et al. | β | 2024 | β |
| Older adults with reduced cerebrovascular reactivity exhibit high white matter hyperintensity burden. | Kapoor A et al. | β | 2024 | β |
| Optical Coherence Tomography Angiography: Revolutionizing Clinical Diagnostics and Treatment in Central Nervous System Disease. | Shen Z et al. | β | 2024 | β |
| Optimizing and benchmarking polygenic risk scores with GWAS summary statistics. | Zhao Z et al. | β | 2024 | β |
| Pathways to Alzheimer's Disease: The Intersecting Roles of Clusterin and Apolipoprotein E in Amyloid-Ξ² Regulation and Neuronal Health. | Laslo A et al. | β | 2024 | β |
| Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. | Kawles A et al. | β | 2024 | β |
| Phishing vulnerability compounded by older age, apolipoprotein E e4 genotype, and lower cognition. | Pehlivanoglu D et al. | β | 2024 | β |
| Physical activity and brain amyloid beta: A longitudinal analysis of cognitively unimpaired older adults. | Slee MG et al. | β | 2024 | β |
| Physical exercise, cognition, and brain health in aging. | Boa Sorte Silva NC et al. | β | 2024 | β |
| Physical Exercise Counteracts Aging-Associated White Matter Demyelination Causing Cognitive Decline. | Butt TH et al. | β | 2024 | β |
| Plasma Biomarkers of Brain Injury and Their Association With Brain MRI and Cognition in Type 1 Diabetes. | Karger AB et al. | β | 2024 | β |
| Predicting the apolipoprotein E Ξ΅4 allele carrier status based on gray matter volumes and cognitive function. | Kim HG et al. | β | 2024 | β |
| Predictors of Improvement after Cognitive Training in Mild Cognitive Impairment: Insights from the Cognitive Training and Neuroplasticity in Mild Cognitive Impairment Trial. | Qian M et al. | β | 2024 | β |
| Presenilin-2 knock-In mice show severe depressive behavior via DVL3 downregulation. | Yoo SS et al. | β | 2024 | β |
| Prevalence and clinicopathological features of primary age-related tauopathy (PART): A large forensic autopsy study. | Yoshida K et al. | β | 2024 | β |
| Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer's disease. | Walker L et al. | β | 2024 | β |
| Promoting Alzheimer's disease research and therapy with stem cell technology. | Cao Z et al. | β | 2024 | β |
| Pros and Cons of APOE4 Homozygosity and Effects on Neuroplasticity, Malnutrition, and Infections in Early Life Adversity, Alzheimer's Disease, and Alzheimer's Prevention. | OriΓ‘ RB et al. | β | 2024 | β |
| Pros and Cons of Human Brain Organoids to Study Alzheimer's Disease. | Sainz A et al. | β | 2024 | β |
| Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis. | Fukuda M et al. | β | 2024 | β |
| Proteomic analysis of APOEΞ΅4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience. | Walker KA et al. | β | 2024 | β |
| Pulse pressure and APOE Ξ΅4 dose interact to affect cerebral blood flow in older adults without dementia. | Edwards L et al. | β | 2024 | β |
| Quantitative Assessment of Conformational Heterogeneity in Apolipoprotein E4 Using Hydrogen-Deuterium Exchange Mass Spectrometry. | Dolai S et al. | β | 2024 | β |
| Quantitative electroencephalography (qEEG), apolipoprotein A-I (APOA-I), and apolipoprotein epsilon 4 (APOE Ι4) alleles for the diagnosis of mild cognitive impairment and Alzheimer's disease. | Niu X et al. | β | 2024 | β |
| Rare genetic variation in fibronectin 1 (FN1) protects against APOEΞ΅4 in Alzheimer's disease. | Bhattarai P et al. | β | 2024 | β |
| Readdressing the Localization of Apolipoprotein E (APOE) in Mitochondria-Associated Endoplasmic Reticulum (ER) Membranes (MAMs): An Investigation of the Hepatic Protein-Protein Interactions of APOE with the Mitochondrial Proteins Lon Protease (LONP1), Mitochondrial Import Receptor Subunit TOM40 (TOMM40) and Voltage-Dependent Anion-Selective Channel 1 (VDAC1). | Rueter J et al. | β | 2024 | β |
| Recent advances in Alzheimer disease genetics. | Nicolas G | β | 2024 | β |
| Recent Advances in the Treatment and Management of Alzheimer's Disease: A Precision Medicine Perspective. | Shukla D et al. | β | 2024 | β |
| Recent Aspects of Periodontitis and Alzheimer's Disease-A Narrative Review. | CichoΕska D et al. | β | 2024 | β |
| Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies. | Sandau US et al. | β | 2024 | β |
| Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E Ι4 allele carriers. | AndrΓ© C et al. | β | 2024 | β |
| Relationships between hourly cognitive variability and risk of Alzheimer's disease revealed with mixed-effects location scale models. | Aschenbrenner AJ et al. | β | 2024 | β |
| Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease. | Vance JM et al. | β | 2024 | β |
| Resting-state functional connectivity abnormalities in subjective cognitive decline: A 7T MRI study. | Pievani M et al. | β | 2024 | β |
| Revealing third-order interactions through the integration of machine learning and entropy methods in genomic studies. | YaldΔ±z B et al. | β | 2024 | β |
| Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies. | Tariot PN et al. | β | 2024 | β |
| Rodent Models of Alzheimer's Disease: Past Misconceptions and Future Prospects. | Collins HM et al. | β | 2024 | β |
| Serum proteomics reveal APOE-Ξ΅4-dependent and APOE-Ξ΅4-independent protein signatures in Alzheimer's disease. | Frick EA et al. | β | 2024 | β |
| Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy. | Bruno F et al. | β | 2024 | β |
| Sex and Gender Differences in Alzheimer's Disease: Genetic, Hormonal, and Inflammation Impacts. | Kolahchi Z et al. | β | 2024 | β |
| Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. | Ferguson CM et al. | β | 2024 | β |
| Single-Cell RNA Sequencing Transcriptomics Revealed HCMV IE2-Related Microglia Responses in Alzheimer's-Like Disease in Transgenic Mice. | Liu F et al. | β | 2024 | β |
| Sleep duration, sleep efficiency, and amyloid Ξ² among cognitively healthy later-life adults: a systematic review and meta-analysis. | Moon C et al. | β | 2024 | β |
| Sleep regulation and host genetics. | Odriozola A et al. | β | 2024 | β |
| Strategies for measuring concentrations and forms of amyloid-Ξ² peptides. | Shen H et al. | β | 2024 | β |
| Supervised latent factor modeling isolates cell-type-specific transcriptomic modules that underlie Alzheimer's disease progression. | Hodgson L et al. | β | 2024 | β |
| SV2A PET shows hippocampal synaptic loss in cognitively unimpaired APOE Ξ΅4/Ξ΅4 homozygotes. | Snellman A et al. | β | 2024 | β |
| Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer's Disease. | Grenon MB et al. | β | 2024 | β |
| The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact. | Kalaria R et al. | β | 2024 | β |
| The advent of Alzheimer treatments will change the trajectory of human aging. | Selkoe DJ | β | 2024 | β |
| The association between urinary sodium and the risk of dementia: Evidence from a population-based cohort study. | Li Y et al. | β | 2024 | β |
| The broken Alzheimer's disease genome. | Gouveia Roque C et al. | β | 2024 | β |
| The cell biology of APOE in the brain. | Windham IA et al. | β | 2024 | β |
| The Cerebrospinal Fluid Free-Glycans Hex<sub>1</sub> and HexNAc<sub>1</sub>Hex<sub>1</sub>Neu5Ac<sub>1</sub> as Potential Biomarkers of Alzheimer's Disease. | KrΓΌger L et al. | β | 2024 | β |
| The CORCOBIA study: Cut-off points of Alzheimer's disease CSF biomarkers in a clinical cohort. | Puig-Pijoan A et al. | β | 2024 | β |
| The current state of apolipoprotein E in dyslipidemia. | Rasmussen KL et al. | β | 2024 | β |
| The effect of the apolipoprotein E Ξ΅4 allele and olfactory function on odor identification networks. | Frank C et al. | β | 2024 | β |
| The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent. | den Hoedt S et al. | β | 2024 | β |
| The Emerging Role of PCSK9 in the Pathogenesis of Alzheimer's Disease: A Possible Target for the Disease Treatment. | Testa G et al. | β | 2024 | β |
| The function of sphingolipids in different pathogenesis of Alzheimer's disease: A comprehensive review. | Wang X et al. | β | 2024 | β |
| The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats. | Rutkowsky JM et al. | β | 2024 | β |
| The Importance of Apolipoprotein E Genetic Testing in the Era of Amyloid Lowering Therapies. | Ronay S et al. | β | 2024 | β |
| The influence of APOE status on rate of cognitive decline. | Morrison C et al. | β | 2024 | β |
| The influence of APOE<sup>Ξ΅4</sup> on the pTau interactome in sporadic Alzheimer's disease. | Thierry M et al. | β | 2024 | β |
| The novel estrogen receptor beta agonist EGX358 and <i>APOE</i> genotype influence memory, vasomotor, and anxiety outcomes in an Alzheimer's mouse model. | Schwabe MR et al. | β | 2024 | β |
| The Potential Role of Enrichment Environment on Plasticity in Alzheimer's Disease Models: Insights About Therapeutic Approaches. | Neves RC et al. | β | 2024 | β |
| Therapeutic Challenges Derived from the Interaction Among Apolipoprotein E, Cholesterol, and Amyloid in Alzheimer's Disease. | Menendez-Gonzalez M | β | 2024 | β |
| The Relationship Between Physical Activity and Non-Modifiable Risk Factors on Alzheimer's Disease and Brain Health Markers: A UK Biobank Study. | Spencer FSE et al. | β | 2024 | β |
| The Role of Non-coding RNAs in Alzheimer's Disease: Pathogenesis, Novel Biomarkers, and Potential Therapeutic Targets. | Saleh O et al. | β | 2024 | β |
| The selection landscape and genetic legacy of ancient Eurasians. | Irving-Pease EK et al. | β | 2024 | β |
| The Single Toxin Origin of Alzheimer's Disease and Other Neurodegenerative Disorders Enables Targeted Approach to Treatment and Prevention. | Tolar M et al. | β | 2024 | β |
| The vascular contribution of apolipoprotein E to Alzheimer's disease. | Chen F et al. | β | 2024 | β |
| Thyroid Hormone and Alzheimer Disease: Bridging Epidemiology to Mechanism. | Escamilla S et al. | β | 2024 | β |
| Towards a Unitary Hypothesis of Alzheimer's Disease Pathogenesis. | Area-Gomez E et al. | β | 2024 | β |
| Trajectories of amyloid beta accumulation - Unveiling the relationship with APOE genotype and cognitive decline. | Wybitul M et al. | β | 2024 | β |
| Unlocking early detection of Alzheimer's disease: The emerging role of nanomaterial-based optical sensors. | Chen CH et al. | β | 2024 | β |
| Unraveling the Genetic Landscape of Neurological Disorders: Insights into Pathogenesis, Techniques for Variant Identification, and Therapeutic Approaches. | Firdaus Z et al. | β | 2024 | β |
| Unveiling recent and ongoing adaptive selection in human populations. | Gao Z | β | 2024 | β |
| Updates in Alzheimer's disease: from basic research to diagnosis and therapies. | Liu E et al. | β | 2024 | β |
| Upstream lipid and metabolic systems are potential causes of Alzheimer's disease, Parkinson's disease and dementias. | Cooper O et al. | β | 2024 | β |
| Vascular Heparan Sulfate and Amyloid-Ξ² in Alzheimer's Disease Patients. | McMillan IO et al. | β | 2024 | β |
| Virus-induced brain pathology and the neuroinflammation-inflammation continuum: the neurochemists view. | Sian-Hulsmann J et al. | β | 2024 | β |
| Vulnerability of the Hippocampus to Insults: Links to Blood-Brain Barrier Dysfunction. | Davidson TL et al. | β | 2024 | β |
| A biomarker-validated time scale in years of disease progression has identified early- and late-onset subgroups in sporadic Alzheimer's disease. | Almkvist O et al. | β | 2023 | β |
| Abnormal Temporal Slowing on EEG Findings in Preclinical Alzheimer's Disease Patients With the ApoE4 Allele: A Pilot Study. | Kim NN et al. | β | 2023 | β |
| Accumulation of amyloid-Ξ² in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging. | Honda K et al. | β | 2023 | β |
| A computational framework for identifying chemical compounds to bind Apolipoprotein E4 for Alzheimer's disease intervention. | Zhai T et al. | β | 2023 | β |
| A Concise Review on Oxidative Stress-Mediated Ferroptosis and Cuproptosis in Alzheimer's Disease. | Huang X | β | 2023 | β |
| Acute stress impairs visual path integration. | Akan O et al. | β | 2023 | β |
| Advances and Applications of Brain Organoids. | Li Y et al. | β | 2023 | β |
| Advances in proteomic phenotyping of microglia in neurodegeneration. | Sunna S et al. | β | 2023 | β |
| Advances in the prevention and treatment of Alzheimer's disease based on oral bacteria. | Zhang M et al. | β | 2023 | β |
| Advances in the Study of APOE and Innate Immunity in Alzheimer's Disease. | Li Y et al. | β | 2023 | β |
| Age and sex differences in the association between APOE genotype and Alzheimer's disease in a Taiwan Chinese population. | Huang LC et al. | β | 2023 | β |
| A global view of the genetic basis of Alzheimer disease. | Reitz C et al. | β | 2023 | β |
| A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease. | Bai H et al. | β | 2023 | β |
| Allelic variation within the major APOE CpG island affects its methylation in the brain of targeted replacement mice expressing human APOE. | Rueter J et al. | β | 2023 | β |
| Altered DNA methylome profiles of blood leukocytes in Chinese patients with mild cognitive impairment and Alzheimer's disease. | Wu S et al. | β | 2023 | β |
| Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression. | Meftah S et al. | β | 2023 | β |
| Alzheimer's disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals. | Pettigrew C et al. | β | 2023 | β |
| Amyloid-Ξ² in Alzheimer's disease - front and centre after all? | Weglinski C et al. | β | 2023 | β |
| Analysis of endothelial gene polymorphisms in Spanish patients with vascular dementia and AlzheimerΒ΄s disease. | Manso-CalderΓ³n R et al. | β | 2023 | β |
| Ancestry-related differences in chromatin accessibility and gene expression of APOE Ξ΅4 are associated with Alzheimer's disease risk. | Celis K et al. | β | 2023 | β |
| An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review. | Singh S et al. | β | 2023 | β |
| Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics. | Cummings J | β | 2023 | β |
| APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice. | Bonnar O et al. | β | 2023 | β |
| APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFΞ²-mediated checkpoints. | Yin Z et al. | β | 2023 | β |
| APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release. | Koutsodendris N et al. | β | 2023 | β |
| APOE and immunity: Research highlights. | Kloske CM et al. | β | 2023 | β |
| APOE and vascular disease: Sequencing and genotyping in general population cohorts. | Rasmussen KL et al. | β | 2023 | β |
| APOE effects on regional tau in preclinical Alzheimer's disease. | Young CB et al. | β | 2023 | β |
| APOE-Genotype and Insulin Modulate Estimated Effect of Dietary Macronutrients on Cognitive Performance: Panel Analyses in Nondiabetic Older Adults at Risk of Dementia. | Norgren J et al. | β | 2023 | β |
| ApoE Mimetic Peptides as Therapy for Traumatic Brain Injury. | Laskowitz DT et al. | β | 2023 | β |
| APOE Peripheral and Brain Impact: APOE4 Carriers Accelerate Their Alzheimer Continuum and Have a High Risk of Suicide in PM<sub>2.5</sub> Polluted Cities. | CalderΓ³n-GarcidueΓ±as L et al. | β | 2023 | β |
| ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer's disease. | Ramsden CE et al. | β | 2023 | β |
| APOE Ξ΅4 Gene Carriers Demonstrate Reduced Retinal Capillary Densities in Asymptomatic Older Adults. | Zhang Z et al. | β | 2023 | β |
| APOE Ξ΅4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly. | Snellman A et al. | β | 2023 | β |
| APOEΞ΅4 potentiates amyloid Ξ² effects on longitudinal tau pathology. | Ferrari-Souza JP et al. | β | 2023 | β |
| APOE Ξ΅4's impact on response to amyloid therapies in early symptomatic Alzheimer's disease: Analyses from multiple clinical trials. | Evans CD et al. | β | 2023 | β |
| APOE Ξ΅4 status and plasma p-tau181 interact to influence cognitive performance among non-demented older adults. | Wang S et al. | β | 2023 | β |
| Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms. | Stuchell-Brereton MD et al. | β | 2023 | β |
| Apolipoprotein E4 targets mitochondria and the mitochondria-associated membrane complex in neuropathology, including Alzheimer's disease. | Mahley RW | β | 2023 | β |
| Apolipoprotein E genotype affects innate susceptibility to <i>Listeria monocytogenes</i> infection in aged male mice. | Cho J et al. | β | 2023 | β |
| Apolipoprotein E in lipid metabolism and neurodegenerative disease. | Yang LG et al. | β | 2023 | β |
| Apolipoprotein E intersects with amyloid-Ξ² within neurons. | Konings SC et al. | β | 2023 | β |
| Apolipoproteinβ E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate. | Mah D et al. | β | 2023 | β |
| Apolipoprotein E Ξ΅4 modulates astrocyte neuronal support functions in the presence of amyloid-Ξ². | Fleeman RM et al. | β | 2023 | β |
| Apolipoprotein Ι4-Associated Protection Against Pediatric Enteric Infections Is a Survival Advantage in Pre-Industrial Populations. | Smith CJ et al. | β | 2023 | β |
| A protein-protein interaction analysis tool for targeted cross-linking mass spectrometry. | Park J et al. | β | 2023 | β |
| A Review on Integrated ZnO-Based SERS Biosensors and Their Potential in Detecting Biomarkers of Neurodegenerative Diseases. | ColniΘΔ A et al. | β | 2023 | β |
| Association between APOE-Ξ΅4 allele and cognitive function is mediated by Alzheimer's disease pathology: a population-based autopsy study in an admixed sample. | Paradela RS et al. | β | 2023 | β |
| Association Between Fluctuations in Blood Lipid Levels Over Time With Incident Alzheimer Disease and Alzheimer Disease-Related Dementias. | Moser ED et al. | β | 2023 | β |
| Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease. | Le Guen Y et al. | β | 2023 | β |
| Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals. | Liuska PJ et al. | β | 2023 | β |
| Association of APOE-Ξ΅4 and GAP-43-related presynaptic loss with Ξ²-amyloid, tau, neurodegeneration, and cognitive decline. | Lan G et al. | β | 2023 | β |
| Association of <i>APOE Ξ΅4</i> Status With Long-term Declines in Odor Sensitivity, Odor Identification, and Cognition in Older US Adults. | GoodSmith MS et al. | β | 2023 | β |
| Association of <i>APOE Ξ΅4/Ξ΅4</i> with fluid biomarkers in patients from the PUMCH dementia cohort. | Shang L et al. | β | 2023 | β |
| Associations between white matter hyperintensities, lacunes, entorhinal cortex thickness, declarative memory and leisure activity in cognitively healthy older adults: A 7-year study. | Hotz I et al. | β | 2023 | β |
| Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration. | Rasmussen KL et al. | β | 2023 | β |
| Astrocytic modulation of neuronal signalling. | Purushotham SS et al. | β | 2023 | β |
| A Traitlike Dimension of Subjective Memory Concern Over 30 Years Among Adult Male Twins. | Bell TR et al. | β | 2023 | β |
| BAYESIAN INFERENCE AND DYNAMIC PREDICTION FOR MULTIVARIATE LONGITUDINAL AND SURVIVAL DATA. | Zou H et al. | β | 2023 | β |
| Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease. | Wang Z et al. | β | 2023 | β |
| Blood Pressure Variability and Cerebral Perfusion Decline: A Post Hoc Analysis of the SPRINT MIND Trial. | Sible IJ et al. | β | 2023 | β |
| Brain apolipoprotein E levels in mice challenged by a Western diet increase in an allele-dependent manner. | Liemisa B et al. | β | 2023 | β |
| Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project. | Garo-Pascual M et al. | β | 2023 | β |
| Can Genetic Markers Predict the Sporadic Form of Alzheimer's Disease? An Updated Review on Genetic Peripheral Markers. | Theron D et al. | β | 2023 | β |
| CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice. | Greco GA et al. | β | 2023 | β |
| Celebrating a Century of Research in Behavioral Genetics. | Plomin R | β | 2023 | β |
| Characterization of Uranyl (UO<sub>2</sub><sup>2+</sup>) Ion Binding to Amyloid Beta (AΞ²) Peptides: Effects on AΞ² Structure and Aggregation. | Berntsson E et al. | β | 2023 | β |
| Chronic stress is associated with specific path integration deficits. | Akan O et al. | β | 2023 | β |
| Cognitive trajectories diverge by genetic risk in a preclinical longitudinal cohort. | Vasiljevic E et al. | β | 2023 | β |
| Comparison of Clinical, Genetic, and Pathologic Features of Limbic and Diffuse Transactive Response DNA-Binding Protein 43 Pathology in Alzheimer's Disease Neuropathologic Spectrum. | Carlos AF et al. | β | 2023 | β |
| Contextualizing the Role of Osteopontin in the Inflammatory Responses of Alzheimer's Disease. | Lalwani RC et al. | β | 2023 | β |
| Cooperation between neurovascular dysfunction and AΞ² in Alzheimer's disease. | Wang N et al. | β | 2023 | β |
| Current Perspectives: Obesity and Neurodegeneration - Links and Risks. | Kueck PJ et al. | β | 2023 | β |
| Current views on meningeal lymphatics and immunity in aging and Alzheimer's disease. | Rego S et al. | β | 2023 | β |
| Design, synthesis, biological activities, and evaluation of molecular docking-dynamics studies of new thiosemicarbazones that may be effective against Alzheimer's disease. | Conger N et al. | β | 2023 | β |
| Detection of early Alzheimer's disease-like molecular alterations in a mouse model expressing human ApoE4. | Rai A et al. | β | 2023 | β |
| Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer's disease: relevance for precision medicine in neurodegenerative diseases. | Lista S et al. | β | 2023 | β |
| Diabetic Retinopathy and Dementia Association, Beyond Diabetes Severity. | Lee CS et al. | β | 2023 | β |
| Diagnosis of Alzheimer's disease by joining dual attention CNN and MLP based on structural MRIs, clinical and genetic data. | Qiang YR et al. | β | 2023 | β |
| Discovery of a Missense Mutation (Q222K) of the <i>APOE</i> Gene from the Australian Imaging, Biomarker and Lifestyle Study. | Roberts BR et al. | β | 2023 | β |
| Disrupted Excitation-Inhibition Balance in Cognitively Normal Individuals at Risk of Alzheimer's Disease. | Fortel I et al. | β | 2023 | β |
| Dissociating effects of aging and genetic risk of sporadic Alzheimer's disease on path integration. | Colmant L et al. | β | 2023 | β |
| Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. | Nemergut M et al. | β | 2023 | β |
| Editorial: Dietary Cholesterol and Dementia Risk. | Middleton LT et al. | β | 2023 | β |
| Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer's disease. | Langella S et al. | β | 2023 | β |
| Effect of physical activity on risk of Alzheimer's disease: A systematic review and meta-analysis of twenty-nine prospective cohort studies. | Zhang X et al. | β | 2023 | β |
| Effects of APOE Ξ΅2 allele on basal forebrain functional connectivity in mild cognitive impairment. | Liu X et al. | β | 2023 | β |
| Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions. | Tobeh NS et al. | β | 2023 | β |
| Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases. | Prasad H et al. | β | 2023 | β |
| Enlarged perivascular spaces are associated with decreased brain tau deposition. | Kang KM et al. | β | 2023 | β |
| Enrichr-KG: bridging enrichment analysis across multiple libraries. | Evangelista JE et al. | β | 2023 | β |
| Epidrugs in the Therapy of Central Nervous System Disorders: A Way to Drive on? | Gladkova MG et al. | β | 2023 | β |
| Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia. | Ford E et al. | β | 2023 | β |
| Evaluating depressive symptoms, BDNF Val66Met, and APOE-Ξ΅4 as moderators of response to computerized cognitive training in heart failure. | Pressler SJ et al. | β | 2023 | β |
| Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction. | Gao XR et al. | β | 2023 | β |
| Extracellular chaperone networks and the export of J-domain proteins. | Braun JEA | β | 2023 | β |
| Extracranial carotid artery atherosclerotic plaque and APOE polymorphisms: a systematic review and meta-analysis. | Culleton S et al. | β | 2023 | β |
| Flavonoids and fibrate modulate apoE4-induced processing of amyloid precursor protein in neuroblastoma cells. | Davra V et al. | β | 2023 | β |
| Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish. | Osterman MD et al. | β | 2023 | β |
| Functional variants identify sex-specific genes and pathways in Alzheimer's Disease. | Bourquard T et al. | β | 2023 | β |
| Fundamental Neurochemistry Review: Microglial immunometabolism in traumatic brain injury. | Strogulski NR et al. | β | 2023 | β |
| Genetic architecture of plasma Alzheimer disease biomarkers. | Bradley J et al. | β | 2023 | β |
| Genetic correlations between Alzheimer's disease and gut microbiome genera. | Cammann D et al. | β | 2023 | β |
| Genetic Phenotypes of Alzheimer's Disease: Mechanisms and Potential Therapy. | Quan M et al. | β | 2023 | β |
| Genetics of Alzheimer's Disease in the African American Population. | Logue MW et al. | β | 2023 | β |
| Genotypic effects of APOE-Ξ΅4 on resting-state connectivity in cognitively intact individuals support functional brain compensation. | Cacciaglia R et al. | β | 2023 | β |
| Genotypic Effects of the TOMM40'523 Variant and APOE on Longitudinal Cognitive Change over 4 Years: The TOMMORROW Study. | Zou H et al. | β | 2023 | β |
| GRN Missense Variants and Familial Alzheimer's Disease: Two Case Reports. | Ingannato A et al. | β | 2023 | β |
| Habitual dietary nitrate intake and cognition in the Australian Imaging, Biomarkers and Lifestyle Study of ageing: A prospective cohort study. | Rajendra A et al. | β | 2023 | β |
| Haptools: a toolkit for admixture and haplotype analysis. | Massarat AR et al. | β | 2023 | β |
| Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association. | Tsao CW et al. | β | 2023 | β |
| Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-Ξ² metabolism. | Ozsan McMillan I et al. | β | 2023 | β |
| Higher Fat-Related Body Composition Measurement and Lower Resting-State Inter-Network Functional Connectivity of APOE Ξ΅4 Carrier in Mild Cognitive Impairment Patients With AΞ² Deposition. | Choi IH et al. | β | 2023 | β |
| Hippocampal connectivity and memory decline in cognitively intact APOE Ξ΅4 carriers. | Baxter LC et al. | β | 2023 | β |
| Honey and Alzheimer's Disease-Current Understanding and Future Prospects. | Shaikh A et al. | β | 2023 | β |
| How does apolipoprotein E genotype influence the relationship between physical activity and Alzheimer's disease risk? A novel integrative model. | de Frutos Lucas J et al. | β | 2023 | β |
| Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor. | Wei Y et al. | β | 2023 | β |
| Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function. | Wu Y et al. | β | 2023 | β |
| Human Leukocyte Antigen (HLA) Modulates the Dependence on Age of the Variability of Synchronous Neural Interactions. | James LM et al. | β | 2023 | β |
| Hypothesis review: Alzheimer's overture guidelines. | Ferrer I | β | 2023 | β |
| <i>APOE</i> genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice. | Balu D et al. | β | 2023 | β |
| <i>APOE</i> genotypes modify the obesity paradox in dementia. | Shinohara M et al. | β | 2023 | β |
| <i>APOE</i> Ξ΅4-Allele in Middle-Aged and Older Autistic Adults: Associations with Verbal Learning and Memory. | Harker SA et al. | β | 2023 | β |
| <i>APOE</i>Ξ΅4 associates with microglial activation independently of AΞ² plaques and tau tangles. | Ferrari-Souza JP et al. | β | 2023 | β |
| <i>APOEΞ΅4</i> and risk of Alzheimer's disease - time to move forward. | Lefterov I et al. | β | 2023 | β |
| Identification of high-performing antibodies for Apolipoprotein E for use in Western Blot and immunoprecipitation. | Ayoubi R et al. | β | 2023 | β |
| Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses. | Li YJ et al. | β | 2023 | β |
| <i>MMP2</i> rs243866 and rs2285053 Polymorphisms and Alzheimer's Disease Risk in Slovak Caucasian Population. | Ocenasova A et al. | β | 2023 | β |
| Implication of tau propagation on neurodegeneration in Alzheimer's disease. | Lamontagne-Kam D et al. | β | 2023 | β |
| Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation. | Valencia-Olvera AC et al. | β | 2023 | β |
| Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells. | Chen Y et al. | β | 2023 | β |
| Insights into the Pathophysiology of Alzheimer's Disease and Potential Therapeutic Targets: A Current Perspective. | Rajah Kumaran K et al. | β | 2023 | β |
| In Silico Design of Natural Inhibitors of ApoE4 from the Plant <i>Moringa oleifera</i>: Molecular Docking and Ab Initio Fragment Molecular Orbital Calculations. | Shaji D et al. | β | 2023 | β |
| Insulin resistance and body mass index are associated with TSPO PET in cognitively unimpaired elderly. | Ekblad LL et al. | β | 2023 | β |
| Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer's disease brains. | Gamache J et al. | β | 2023 | β |
| Interaction between <i>KLOTHO</i>-VS Heterozygosity and <i>APOE</i> Ξ΅4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer's Disease. | Chen XR et al. | β | 2023 | β |
| Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases. | Reed AL et al. | β | 2023 | β |
| Inter- and intra-chromosomal modulators of the APOE Ι2 and Ι4 effects on the Alzheimer's disease risk. | Nazarian A et al. | β | 2023 | β |
| Investigation of the Relationship between Apolipoprotein E Alleles and Serum Lipids in Alzheimer's Disease: A Meta-Analysis. | Xu H et al. | β | 2023 | β |
| In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis. | Lee H et al. | β | 2023 | β |
| Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia. | Fernandez A et al. | β | 2023 | β |
| Leveraging African American family connectors for Alzheimer's disease genomic studies. | Byfield G et al. | β | 2023 | β |
| LilrB3 is a putative cell surface receptor of APOE4. | Zhou J et al. | β | 2023 | β |
| Lipid in microglial biology - from material to mediator. | Yamamoto S et al. | β | 2023 | β |
| Lipoprotein Metabolism, Protein Aggregation, and Alzheimer's Disease: A Literature Review. | Grao-Cruces E et al. | β | 2023 | β |
| Liquid-liquid phase separation in synaptopathies. | Jiang H et al. | β | 2023 | β |
| Longitudinal changes in <sup>18</sup>F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations. | Luckett ES et al. | β | 2023 | β |
| Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes. | Konstantinidis E et al. | β | 2023 | β |
| Mediation of Reduced Hippocampal Volume by Cerebral Amyloid Angiopathy in Pathologically Confirmed Patients with Alzheimer's Disease. | Nagaraja N et al. | β | 2023 | β |
| Microglia in Alzheimer's disease: pathogenesis, mechanisms, and therapeutic potentials. | Miao J et al. | β | 2023 | β |
| Microglial APOE4: more is less and less is more. | Eskandari-Sedighi G et al. | β | 2023 | β |
| microRNA-132 regulates gene expression programs involved in microglial homeostasis. | Walgrave H et al. | β | 2023 | β |
| MicroRNAs in Extracellular Vesicles of Alzheimer's Disease. | Li W et al. | β | 2023 | β |
| Microvascular Contributions to Alzheimer Disease Pathogenesis: Is Alzheimer Disease Primarily an Endotheliopathy? | Tarawneh R | β | 2023 | β |
| Modifiable cardiovascular risk factors and genetics for targeted prevention of dementia. | Juul Rasmussen I et al. | β | 2023 | β |
| Modulation of associations between education years and cortical volume in Alzheimer's disease vulnerable brain regions by AΞ² deposition and <i>APOE</i> Ξ΅4 carrier status in cognitively normal older adults. | Kim HB et al. | β | 2023 | β |
| Molecular genetics of neuropsychiatric illness: some musings. | Janardhanan M et al. | β | 2023 | β |
| Molecular modeling of apoE in complexes with Alzheimer's amyloid-Ξ² fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids. | Lewkowicz E et al. | β | 2023 | β |
| Myeloid masquerade: Microglial transcriptional signatures in retinal development and disease. | Pitts KM et al. | β | 2023 | β |
| Neurogenetic motor disorders. | Younger DS | β | 2023 | β |
| Neuronal ApoE4 in Alzheimer's disease and potential therapeutic targets. | Zhang L et al. | β | 2023 | β |
| Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits. | Koutsodendris N et al. | β | 2023 | β |
| Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer's and Parkinson's Diseases. | Javed H et al. | β | 2023 | β |
| Neutrophil-Mediated Progression of Mild Cognitive Impairment to Dementia. | Cho K | β | 2023 | β |
| [New data on the pathophysiology of ischemic stroke: epigenetic mechanisms in focus]. | Aitbaev KA et al. | β | 2023 | β |
| Omega-3 fatty acids and cognitive function. | Welty FK | β | 2023 | β |
| Outreach, Screening, and Randomization of APOE Ξ΅4 Carriers into an Alzheimer's Prevention Trial: A global Perspective from the API Generation Program. | Walsh T et al. | β | 2023 | β |
| Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders. | De Marchi F et al. | β | 2023 | β |
| Particle Nanoarchitectonics for Nanomedicine and Nanotherapeutic Drugs with Special Emphasis on Nasal Drugs and Aging. | Aziz T et al. | β | 2023 | β |
| Past and future episodic detail retrieval is reduced among clinically normal older adults at higher genetic risk for late-onset Alzheimer's disease. | Acevedo-Molina MC et al. | β | 2023 | β |
| Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer's Disease-Related Biomarkers. | Schork NJ et al. | β | 2023 | β |
| Peripheral metabolism of lipoprotein-amyloid beta as a risk factor for Alzheimer's disease: potential interactive effects of APOE genotype with dietary fats. | D'Alonzo ZJ et al. | β | 2023 | β |
| Pharmacogenomics of Dementia: Personalizing the Treatment of Cognitive and Neuropsychiatric Symptoms. | Vuic B et al. | β | 2023 | β |
| Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma AΞ²40/42 Ratio as a Biomarker of Amyloid-Ξ² Amyloidosis in Alzheimer's Disease. | Nakamura T et al. | β | 2023 | β |
| Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer's disease and mild cognitive impairment. | Giannisis A et al. | β | 2023 | β |
| Plasma IAPP-Autoantibody Levels in Alzheimer's Disease Patients Are Affected by <i>APOE4</i> Status. | PoceviΔiΕ«tΔ D et al. | β | 2023 | β |
| Polygenic burden of short tandem repeat expansions promote risk for Alzheimerβs disease | Guo MH et al. | β | 2023 | β |
| Polygenic Propensity for Longevity, APOE-Ξ΅4 Status, Dementia Diagnosis, and Risk for Cause-Specific Mortality: A Large Population-Based Longitudinal Study of Older Adults. | Ajnakina O et al. | β | 2023 | β |
| Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16Β years. | Najar J et al. | β | 2023 | β |
| Predictive link between systemic metabolism and cytokine signatures in the brain of apolipoprotein E Ξ΅4 mice. | Fleeman RM et al. | β | 2023 | β |
| Predictors of cognitive and physical decline: Results from the Health Aging and Body Composition Study. | Handing EP et al. | β | 2023 | β |
| Presymptomatic Reduction of Individuality in theΒ App<sup>NL-F</sup> Knockin Model of Alzheimer's Disease. | Ehret F et al. | β | 2023 | β |
| Prevalent stroke, age of its onset, and post-stroke lifestyle in relation to dementia: A prospective cohort study. | Zhong W et al. | β | 2023 | β |
| Proposal of novel ApoE4 inhibitors from the natural spice Cinnamon for the treatment of Alzheimer's disease: Ab initio molecular simulations. | Shaji D et al. | β | 2023 | β |
| Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPΞ² levels in cerebrospinal fluid and 2D/3D cell culture models. | Wittrahm R et al. | β | 2023 | β |
| Pulse pressure trajectories predict brain microstructure in community-dwelling older adults: Associations with executive function and modification by APOE. | Parada H et al. | β | 2023 | β |
| Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP. | Cakir Z et al. | β | 2023 | β |
| Ranking the risk factors for Alzheimer's disease; findings from the UK Biobank study. | Allwright M et al. | β | 2023 | β |
| Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology. | Lau SF et al. | β | 2023 | β |
| Redox Imbalance in Neurological Disorders in Adults and Children. | Rey F et al. | β | 2023 | β |
| Reexamining the Causes and Effects of Cholesterol Deposition in the Brains of Patients with Alzheimer's Disease. | Hu ZL et al. | β | 2023 | β |
| Regional White Matter Hyperintensities and Alzheimer's Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment. | Newton P et al. | β | 2023 | β |
| Regulation of the hippocampal translatome by Apoer2-ICD release. | Wasser CR et al. | β | 2023 | β |
| Relationship Between <i>FERMT2</i>, <i>CELF1</i>, <i>COPI</i>, <i>CHRNA2</i>, and <i>ABCA7</i> Genetic Polymorphisms and Alzheimer's Disease Risk in the Southern Chinese Population. | Ding Y et al. | β | 2023 | β |
| Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia. | Poliakova T et al. | β | 2023 | β |
| Safety and efficacy of lecanemab for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials. | Qiao Y et al. | β | 2023 | β |
| Single-cell analysis reveals inflammatory interactions driving macular degeneration. | Kuchroo M et al. | β | 2023 | β |
| Sister haplotypes and recombination disequilibrium: a new approach to identify associations of haplotypes with complex diseases. | Liao SY et al. | β | 2023 | β |
| Six mitophagy-related hub genes as peripheral blood biomarkers of Alzheimer's disease and their immune cell infiltration correlation. | Zhao K et al. | β | 2023 | β |
| Soluble TREM2 Concentrations in the Cerebrospinal Fluid Correlate with the Severity of Neurofibrillary Degeneration, Cognitive Impairment, and Inflammasome Activation in Alzheimer's Disease. | Ε paniΔ PopovaΔki E et al. | β | 2023 | β |
| Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of <i>APOE4</i> Homozygotes and Non-<i>APOE4</i> Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline. | den Hoedt S et al. | β | 2023 | β |
| Spinal apolipoprotein E is involved in inflammatory pain via regulating lipid metabolism and glial activation in the spinal dorsal horn. | Liu S et al. | β | 2023 | β |
| Statistical Methods for Disease Risk Prediction with Genotype Data. | Xia X et al. | β | 2023 | β |
| Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice. | De La Torre AL et al. | β | 2023 | β |
| Study of Alzheimer's disease- and frontotemporal dementia-associated genes in the Cretan Aging Cohort. | Mathioudakis L et al. | β | 2023 | β |
| Suppression of Wnt/Ξ²-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease. | Macyczko JR et al. | β | 2023 | β |
| Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease. | Blanco K et al. | β | 2023 | β |
| Systolic Blood Pressure Is Associated with Increased Brain Amyloid Load in Mild Cognitively Impaired Participants: Alzheimer's Disease Neuroimaging Initiatives Study. | Fungwe TV et al. | β | 2023 | β |
| Targeting apolipoprotein E and N-terminal amyloid Ξ²-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer's mice. | Sawmiller D et al. | β | 2023 | β |
| The Alzheimer's Disease Mitochondrial Cascade Hypothesis: A Current Overview. | Swerdlow RH | β | 2023 | β |
| The amyloid cascade hypothesis: an updated critical review. | Kepp KP et al. | β | 2023 | β |
| The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation. | Nelson MR et al. | β | 2023 | β |
| The association between white matter hyperintensities and amyloid and tau deposition. | Alban SL et al. | β | 2023 | β |
| The association of microbial infection and adaptive immune cell activation in Alzheimer's disease. | Clement M | β | 2023 | β |
| The Association of Selected GWAS Reported AD Risk Loci with CSF Biomarker Levels and Cognitive Decline in Slovenian Patients. | Vogrinc D et al. | β | 2023 | β |
| The blood-brain barrier, a key bridge to treat neurodegenerative diseases. | Hang Z et al. | β | 2023 | β |
| The cholesterol depleting agent, (2-Hydroxypropyl)-Γ-cyclodextrin, does not affect disease progression in SOD1<sup>G93A</sup> mice. | Greensmith L et al. | β | 2023 | β |
| The Fault in Our Astrocytes - cause or casualties of proteinopathies of ALS/FTD and other neurodegenerative diseases? | Bustos LM et al. | β | 2023 | β |
| The Functions and Phenotypes of Microglia in Alzheimer's Disease. | Fujikawa R et al. | β | 2023 | β |
| The Future of Precision Medicine in the Cure of Alzheimer's Disease. | Arafah A et al. | β | 2023 | β |
| The Impact of Apolipoprotein E (<i>APOE</i>) Epigenetics on Aging and Sporadic Alzheimer's Disease. | Lozupone M et al. | β | 2023 | β |
| The Implication of Glial Metabotropic Glutamate Receptors in Alzheimer's Disease. | de Lima IBQ et al. | β | 2023 | β |
| The Janus-Faced Role of Lipid Droplets in Aging: Insights from the Cellular Perspective. | Bresgen N et al. | β | 2023 | β |
| The Joint Effect of Body Mass Index and Serum Lipid Levels on Incident Dementia among Community-Dwelling Older Adults. | Lei Q et al. | β | 2023 | β |
| The landscape of metabolic brain alterations in Alzheimer's disease. | Batra R et al. | β | 2023 | β |
| The mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo. | Rueter J et al. | β | 2023 | β |
| The neuroimmune axis of Alzheimer's disease. | Jorfi M et al. | β | 2023 | β |
| The role of ApoE-mediated microglial lipid metabolism in brain aging and disease. | Yen JJ et al. | β | 2023 | β |
| The Role of Clinical Assessment in the Era of Biomarkers. | Carlos AF et al. | β | 2023 | β |
| The role of mitochondrial genome abundance in Alzheimer's disease. | Harerimana NV et al. | β | 2023 | β |
| The role of opioid receptors in modulating Alzheimer's Disease. | Tanguturi P et al. | β | 2023 | β |
| The unique neuropathological vulnerability of the human brain to aging. | I F | β | 2023 | β |
| The use of subjective cognitive complaints for detecting mild cognitive impairment in older adults across cultural and linguistic groups: A comparison of the Cognitive Function Instrument to the Montreal Cognitive Assessment. | Li C et al. | β | 2023 | β |
| TSPO Modulates Oligomeric Amyloid-Ξ²-Induced Monocyte Chemotaxis: Relevance for Neuroinflammation in Alzheimer's Disease. | Conti E et al. | β | 2023 | β |
| Understanding the relationships between physiological and psychosocial stress, cortisol and cognition. | James KA et al. | β | 2023 | β |
| VEGF controls microglial phagocytic response to amyloid-Ξ². | de Gea P et al. | β | 2023 | β |
| Visit-to-Visit Blood Pressure Variability and Cognitive Decline in Apolipoprotein Ι4 Carriers versus Apolipoprotein Ι3 Homozygotes. | Sible IJ et al. | β | 2023 | β |
| White matter hyperintensities in cholinergic pathways are associated with dementia severity in e4 carriers but not in non-carriers. | Yu MC et al. | β | 2023 | β |
| A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE. | Watts JA et al. | β | 2022 | β |
| Adenosine receptor signalling in Alzheimer's disease. | Trinh PNH et al. | β | 2022 | β |
| A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program. | Litkowski EM et al. | β | 2022 | β |
| A diet rich in docosahexaenoic acid enhances reactive astrogliosis and ramified microglia morphology in apolipoprotein E epsilon 4-targeted replacement mice. | Chappus-McCendie H et al. | β | 2022 | β |
| A healthy mind in a healthy body: Effects of arteriosclerosis and other risk factors on cognitive aging and dementia. | Fabiani M et al. | β | 2022 | β |
| A locus at 19q13.31 significantly reduces the ApoE Ξ΅4 risk for Alzheimer's Disease in African Ancestry. | Rajabli F et al. | β | 2022 | β |
| Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer's Disease Patients. | Lopez-Font I et al. | β | 2022 | β |
| Alzheimer's Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound. | Baazaoui N et al. | β | 2022 | β |
| Alzheimer's disease related single nucleotide polymorphisms and correlation with intracerebral hemorrhage incidence. | Sawyer RP et al. | β | 2022 | β |
| A multi-network comparative analysis of whole-transcriptome and translatome reveals the effect of high-fat diet on APP/PS1 mice and the intervention with Chinese medicine. | Gao W et al. | β | 2022 | β |
| A "multi-omics" analysis of blood-brain barrier and synaptic dysfunction in APOE4 mice. | Barisano G et al. | β | 2022 | β |
| Amyloidogenesis and Neurotrophic Dysfunction in Alzheimer's Disease: Do They have a Common Regulating Pathway? | Jiao F et al. | β | 2022 | β |
| Amyloid-Ξ² and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score. | Tomassen J et al. | β | 2022 | β |
| An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration. | Periasamy A et al. | β | 2022 | β |
| An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research. | Kline RA et al. | β | 2022 | β |
| ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis. | Staurenghi E et al. | β | 2022 | β |
| APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-ΞΊB activation. | Arnaud L et al. | β | 2022 | β |
| APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. | Blanchard JW et al. | β | 2022 | β |
| APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases. | FernΓ‘ndez-Calle R et al. | β | 2022 | β |
| APOE Ξ΅4 genotype, amyloid-Ξ², and sex interact to predict tau in regions of high APOE mRNA expression. | Dincer A et al. | β | 2022 | β |
| APOE Ξ΅4 influences cognitive decline positively in APP and negatively in PSEN1 mutation carriers with autosomal-dominant Alzheimer's disease. | Almkvist O et al. | β | 2022 | β |
| Apolipoprotein E Genotype e2: Neuroprotection and Its Limits. | Kim H et al. | β | 2022 | β |
| Apolipoprotein E loss of function: Influence on murine brain markers of physiology and pathology. | Buchanan H et al. | β | 2022 | β |
| A review of brain imaging biomarker genomics in Alzheimer's disease: implementation and perspectives. | Li L et al. | β | 2022 | β |
| Association of Alzheimer's disease polygenic risk scores with amyloid accumulation in cognitively intact older adults. | Luckett ES et al. | β | 2022 | β |
| Association of CSF GAP-43 and <i>APOE</i> Ξ΅4 with Cognition in Mild Cognitive Impairment and Alzheimer's Disease. | Zhu Y et al. | β | 2022 | β |
| Association of rs2072446 in the NGFR gene with the risk of Alzheimer's disease and amyloid-Ξ² deposition in the brain. | He CY et al. | β | 2022 | β |
| Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation. | Saroja SR et al. | β | 2022 | β |
| Biomarkers Related to Synaptic Dysfunction to Discriminate Alzheimer's Disease from Other Neurological Disorders. | Piccoli T et al. | β | 2022 | β |
| Blood-Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders. | AragΓ³n-GonzΓ‘lez A et al. | β | 2022 | β |
| Building in vitro models of the brain to understand the role of <i>APOE</i> in Alzheimer's disease. | Pinals RL et al. | β | 2022 | β |
| Causal inference for semi-competing risks data. | Nevo D et al. | β | 2022 | β |
| Cell type-specific histone acetylation profiling of Alzheimer's disease subjects and integration with genetics. | Ramamurthy E et al. | β | 2022 | β |
| Central nervous system cholesterol metabolism in health and disease. | Ho WY et al. | β | 2022 | β |
| Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer's disease. | Mumtaz I et al. | β | 2022 | β |
| Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired. | Lehtola JM et al. | β | 2022 | β |
| Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals. | Hong YJ et al. | β | 2022 | β |
| Correlations between sleep disturbance and brain structures associated with neurodegeneration in the National Alzheimer's Coordinating Center Uniform Data Set. | Burke S et al. | β | 2022 | β |
| Current understanding of the interactions between metal ions and Apolipoprotein E in Alzheimer's disease. | Zhang Y et al. | β | 2022 | β |
| Differential Neuropathology, Genetics, and Transcriptomics in Two Kindred Cases with Alzheimer's Disease and Lewy Body Dementia. | Palmieri I et al. | β | 2022 | β |
| Disclosure of Genetic Risk Factors for Alzheimer's Disease to Cognitively Healthy Individuals-From Current Practice towards a Personalised Medicine Scenario. | Galluzzi S et al. | β | 2022 | β |
| Effects of non-modifiable risk factors of Alzheimer's disease on intracortical myelin content. | Fernandez-Alvarez M et al. | β | 2022 | β |
| Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults. | Pa J et al. | β | 2022 | β |
| Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia. | Zhao N et al. | β | 2022 | β |
| Emerging roles of innate and adaptive immunity in Alzheimer's disease. | Chen X et al. | β | 2022 | β |
| Enhanced activity of Alzheimer disease-associated variant of protein kinase CΞ± drives cognitive decline in a mouse model. | LordΓ©n G et al. | β | 2022 | β |
| Evidence of emerging BBB changes in mid-age apolipoprotein E epsilon-4 carriers. | Alruwais NM et al. | β | 2022 | β |
| Exploring the combined effects of sleep apnea and APOE-e4 on biomarkers of Alzheimer's disease. | Turner AD et al. | β | 2022 | β |
| Fecal Microbiota Transplantation Reduces Pathology and Improves Cognition in a Mouse Model of Alzheimer's Disease. | Elangovan S et al. | β | 2022 | β |
| Functional diversity of apolipoprotein E: from subcellular localization to mitochondrial function. | Rueter J et al. | β | 2022 | β |
| Gene-environment interactions in Alzheimer disease: the emerging role of epigenetics. | Migliore L et al. | β | 2022 | β |
| Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations. | Gardner OK et al. | β | 2022 | β |
| Genetic Variants at the <i>APOE</i> Locus Predict Cardiometabolic Traits and Metabolic Syndrome: A Taiwan Biobank Study. | Yeh KH et al. | β | 2022 | β |
| HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer's Disease Pathogenesis. | BorrΓ s C et al. | β | 2022 | β |
| How Alpha Linolenic Acid May Sustain Blood-Brain Barrier Integrity and Boost Brain Resilience against Alzheimer's Disease. | Leikin-Frenkel A et al. | β | 2022 | β |
| HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease. | Dong Y et al. | β | 2022 | β |
| Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol. | Glasauer SMK et al. | β | 2022 | β |
| <i>APOE</i> Allele Frequency in Southern Greece: Exploring the Role of Geographical Gradient in the Greek Population. | Papastefanopoulou V et al. | β | 2022 | β |
| <i>ApoE</i>/<i>NOS3</i> Knockout Mice as a Novel Cardiovascular Disease Model of Hypertension and Atherosclerosis. | Liu K et al. | β | 2022 | β |
| If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline? | Haass C et al. | β | 2022 | β |
| Immunosenescence and Aging: Neuroinflammation Is a Prominent Feature of Alzheimer's Disease and Is a Likely Contributor to Neurodegenerative Disease Pathogenesis. | Bowirrat A | β | 2022 | β |
| In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated. | Ye F et al. | β | 2022 | β |
| Infectious origin of Alzheimer's disease: Amyloid beta as a component of brain antimicrobial immunity. | Vojtechova I et al. | β | 2022 | β |
| Influence of genetic and cardiometabolic risk factors in Alzheimer's disease. | Pasqualetti G et al. | β | 2022 | β |
| Interactions between apolipoprotein E, sex, and amyloid-beta on cerebrospinal fluid p-tau levels in the European prevention of Alzheimer's dementia longitudinal cohort study (EPAD LCS). | Saunders TS et al. | β | 2022 | β |
| Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1<i>Ξ±</i>/XBP1s/CHOP Pathway in Vascular Dementia Rats. | Peng D et al. | β | 2022 | β |
| Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer's Disease and Identifying Promising Drug Targets. | FiΕ‘ar Z | β | 2022 | β |
| Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology. | Lazar AN et al. | β | 2022 | β |
| Low-Density Lipoprotein Receptor-Related Protein 8 at the Crossroad between Cancer and Neurodegeneration. | Passarella D et al. | β | 2022 | β |
| Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects. | Berntsson E et al. | β | 2022 | β |
| Microglial efferocytosis: Diving into the Alzheimer's disease gene pool. | Romero-Molina C et al. | β | 2022 | β |
| Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native AΞ² oligomers to rats. | Baerends E et al. | β | 2022 | β |
| Modulations of bioactive lipids and their receptors in postmortem Alzheimer's disease brains. | Kurano M et al. | β | 2022 | β |
| Monobutyrin and monovalerin improve gut-blood-brain biomarkers and alter gut microbiota composition in high-fat fed apolipoprotein-E-knockout rats. | Nguyen TD et al. | β | 2022 | β |
| Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases. | Islam F et al. | β | 2022 | β |
| Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts. | Betthauser TJ et al. | β | 2022 | β |
| Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer's disease in a multigenerational Colombian Family. | Tejada Moreno JA et al. | β | 2022 | β |
| Neurodegeneration Markers Galectin-3 and Apolipoprotein E Are Elevated in the Aqueous Humor of Eyes With Glaucoma. | Pitts KM et al. | β | 2022 | β |
| Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV. | Di Liberto G et al. | β | 2022 | β |
| Neuroprotective Effects of Resveratrol by Modifying Cholesterol Metabolism and AΞ² Processing in SAMP8 Mice. | SΓ‘nchez-Melgar A et al. | β | 2022 | β |
| Novel molecular mechanisms in Alzheimer's disease: The potential role of DEK in disease pathogenesis. | Greene AN et al. | β | 2022 | β |
| Observational studies in Alzheimer disease: bridging preclinical studies and clinical trials. | Brenowitz WD et al. | β | 2022 | β |
| Ovariectomy-induced hormone deprivation aggravates AΞ²<sub>1-42</sub> deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer's disease. | Farkas S et al. | β | 2022 | β |
| Perivascular spaces as a potential biomarker of Alzheimer's disease. | Lynch M et al. | β | 2022 | β |
| Plasma high-density lipoprotein cargo is altered in Alzheimer's disease and is associated with regional brain volume. | Pedrini S et al. | β | 2022 | β |
| Polygenic resilience scores capture protective genetic effects for Alzheimer's disease. | Hou J et al. | β | 2022 | β |
| Polygenic score for Alzheimer's disease identifies differential atrophy in hippocampal subfield volumes. | Kannappan B et al. | β | 2022 | β |
| Potential value of cerebrospinal fluid Ξ±-synuclein in the identification of postoperative delirium undergoing knee/hip arthroplasty: The perioperative neurocognitive disorder and biomarker lifestyle study. | Lin X et al. | β | 2022 | β |
| Research advances in the study of sleep disorders, circadian rhythm disturbances and Alzheimer's disease. | Xiong X et al. | β | 2022 | β |
| Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice. | Mhatre-Winters I et al. | β | 2022 | β |
| Sex and gender differences in dementia. | Salwierz P et al. | β | 2022 | β |
| Shared Risk Factors between Dementia and Atherosclerotic Cardiovascular Disease. | Nordestgaard LT et al. | β | 2022 | β |
| Sirtuins promote brain homeostasis, preventing Alzheimer's disease through targeting neuroinflammation. | Watroba M et al. | β | 2022 | β |
| SNP-by-CpG Site Interactions in <i>ABCA7</i> Are Associated with Cognition in Older African Americans. | Chaar DL et al. | β | 2022 | β |
| SNPs in apolipoproteins contribute to sex-dependent differences in blood lipids before and after a high-fat dietary challenge in healthy U.S. adults. | Wang YE et al. | β | 2022 | β |
| Structural Determinant of Ξ²-Amyloid Formation: From Transmembrane Protein Dimerization to Ξ²-Amyloid Aggregates. | Papadopoulos N et al. | β | 2022 | β |
| Suicide-Related Single Nucleotide Polymorphisms, <i>rs4918918</i> and <i>rs10903034</i>: Association with Dementia in Older Adults. | Abramova O et al. | β | 2022 | β |
| Tau immunotherapy in Alzheimer's disease and progressive supranuclear palsy. | Karimi N et al. | β | 2022 | β |
| Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease. | Blasco Tavares Pereira Lopes F et al. | β | 2022 | β |
| The COVID-19 pandemic and Alzheimer's disease: mutual risks and mechanisms. | Chen F et al. | β | 2022 | β |
| The Immune System as a Therapeutic Target for Alzheimer's Disease. | Zieneldien T et al. | β | 2022 | β |
| The influence of 17q21.31 and <i>APOE</i> genetic ancestry on neurodegenerative disease risk. | Harerimana NV et al. | β | 2022 | β |
| The Role of the Thioredoxin System in Brain Diseases. | BjΓΈrklund G et al. | β | 2022 | β |
| Unravelling the relationship between amyloid accumulation and brain network function in normal aging and very mild cognitive decline: a longitudinal analysis. | Moffat G et al. | β | 2022 | β |
| Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis. | Bracher-Smith M et al. | β | 2022 | β |
| Whole patient knowledge modeling of COVID-19 symptomatology reveals common molecular mechanisms. | Brock S et al. | β | 2022 | β |