The genetic basis of neuroticism.
paper
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- Authors
- Flint, Jonathan
- Year
- 2004
- Journal
- Neuroscience and biobehavioral reviews
- PMID
- 15225973
- DOI
- 10.1016/j.neubiorev.2004.01.004
Gray has drawn upon genetic evidence to argue for the existence of rodent emotionality, a model of human neuroticism. With the advent of molecular mapping techniques it has become possible to test this hypothesis. Here I review the progress that has been made, largely in animal genetic studies, demonstrating that a common set of genes act pleiotropically on measures of emotionality. More recently, evidence has emerged supporting the view that the same genes influence variation in both rodent and human phenotypes.
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|---|---|---|
| Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. | 2015 | 25993607 |
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