Are there meaningful etiological differences within antisocial behavior? Results of a meta-analysis.
- Authors
- Burt, S Alexandra
- Year
- 2009
- Journal
- Clinical psychology review
- PMID
- 19193479
- DOI
- 10.1016/j.cpr.2008.12.004
There is mounting evidence of etiologically driven distinctions between aggressive (AGG) and non-aggressive rule-breaking (RB) forms of antisocial behavior. To date, however, these differences remain somewhat speculative. The current meta-analysis of twin and adoption studies sought to clarify these distinctions by comparing meta-analytic estimates of genetic, shared environmental, and non-shared environmental influences across AGG and RB to more clearly ascertain whether they evidence differential patterns of genetic and environmental influence. A comprehensive literature search resulted in the collection of 103 twin and adoption studies, of which 15 RB samples and 19 AGG samples were ultimately included in the analyses. Results reveal clear evidence of etiological distinctions between AGG and RB. Namely, AGG appears to be a highly heritable condition (genetic factors account for 65% of the variance), with little role for the shared or common environment, particularly after childhood. By contrast, while genetic influences also contribute to RB (48% of the variance), there is an important role for shared environmental effects as well (18% of the variance). Such findings are indicative of meaningful etiologic distinctions between aggressive and rule-breaking forms of antisocial behavior, and underscore the advantage of differentiating between these behavioral subtypes when studying the causal processes that underlie antisocial behavior.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Annual Research Review: Early conduct problems - precursors, outcomes, and etiology. | Hyde LW et al. | β | 2026 | β |
| Behavioral Tendencies of Hostility: A New Approach to Personality Assessment Based on Person-in-Context Units. | Vohra P et al. | β | 2025 | β |
| Brain-based gene expression and corresponding behavioural relevance of risk genes for broad antisocial behaviour. | Rokicki J et al. | β | 2025 | β |
| Callous-unemotional traits, cognitive functioning, and externalizing problems in a propensity-matched sample from the ABCD study. | Murtha K et al. | β | 2025 | β |
| Genetic risk for trait aggression and alcohol use predict unique facets of alcohol-related aggression. | Spychala KM et al. | β | 2025 | β |
| Polygenic risk and hostile environments: Links to stable and dynamic antisocial behaviors across adolescence. | Acland EL et al. | β | 2025 | β |
| Shedding Light on Antisocial Behavior Through Genetically Informed Research. | Pezzoli P et al. | β | 2025 | β |
| The hierarchical structure and longitudinal measurement invariance of externalizing symptoms in the adolescent brain and cognitive development study. | Vize CE et al. | β | 2025 | β |
| Trajectories of childhood bullying behaviors and conduct problems: Associations with cognitive functioning in a nationally representative cohort study. | ThΓ©riault-Couture F et al. | β | 2025 | β |
| Alcohol Use Disorder Polygenic Risk Scores and Trajectories of Early Adolescent Externalizing Behaviors: Examining the Role of Parenting and Family Conflict in the Racially/Ethnically Diverse ABCD Sample. | Trevino AD et al. | β | 2024 | β |
| An examination of early socioeconomic status and neighborhood disadvantage as independent predictors of antisocial behavior: A longitudinal adoption study. | Gresko SA et al. | β | 2024 | β |
| Co-developmental trajectories of aggression and rule-breaking from middle childhood to early adolescence: individual and environmental predictors. | Cheng J et al. | β | 2024 | β |
| Moral Disengagement in Adolescent Offenders: Its Relationship with Antisocial Behavior and Its Presence in Offenders of the Law and School Norms. | Agudelo Rico D et al. | β | 2024 | β |
| The neurobiology of antisocial personality disorder. | Choy O et al. | β | 2024 | β |
| Added value of neurotechnology for forensic psychiatric and psychological assessment. | Kempes M | β | 2023 | β |
| Aggression and Depression in Chinese Early Adolescents: Same-Domain and Cross-Domain Effects in Friendships. | Zhou J et al. | β | 2023 | β |
| Health of Convicted Persons in the Third Generation of the Longitudinal Cambridge Study in Delinquent Development. | Skinner GCM et al. | β | 2023 | β |
| Offending Trajectories in Violent Offenders: Criminal History and Early Life Risk Factors. | TΓ€rnhΓ€ll A et al. | β | 2023 | β |
| Parental imprisonment, delinquent behavior, and BMI gain in a U.S. nationally representative cohort study of adolescents and adults ages 12-32. | Roettger ME et al. | β | 2023 | β |
| The developmental trends of parental self-efficacy and adolescents' rule-breaking behaviors in the Italian context: A 7-wave latent growth curve study. | Remondi C et al. | β | 2023 | β |
| The development of youth antisocial behavior across time and context: A systematic review and integration of person-centered and variable-centered research. | Carroll SL et al. | β | 2023 | β |
| Developmental Trajectories of Delinquent and Aggressive Behavior: Evidence for Differential Heritability. | Isen J et al. | β | 2022 | β |
| Epigenetics of Aggression. | Duclot F et al. | β | 2022 | β |
| Familial resemblance, citizenship, and counterproductive work behavior: A combined twin, adoption, parent-offspring, and spouse approach. | Anderson EL et al. | β | 2022 | β |
| Gender Moderates the Association Between Exposure to Interpersonal Violence and Intermittent Explosive Disorder Diagnosis. | Krick LC et al. | β | 2022 | β |
| Heritability of Bullying and Victimization in Children and Adolescents: Moderation by the KiVa Antibullying Program. | Johansson A et al. | β | 2022 | β |
| Influence of Betrayal Trauma on Psychopathy. | Yalch MM et al. | β | 2022 | β |
| Long-term Health and Social Outcomes in Children and Adolescents Placed in Out-of-Home Care. | Sariaslan A et al. | β | 2022 | β |
| Psychopathy: Current Knowledge and Future Directions. | Patrick CJ | β | 2022 | β |
| Shared genomic architectures of COVID-19 and antisocial behavior. | Adams CD et al. | β | 2022 | β |
| The Genetic, Environmental, and Cultural Forces Influencing Youth Antisocial Behavior Are Tightly Intertwined. | Burt SA | β | 2022 | β |
| Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis. | Tielbeek JJ et al. | β | 2022 | β |
| Using age difference and sex similarity to detect evidence of sibling influence on criminal offending. | Mikkonen J et al. | β | 2022 | β |
| A multilevel examination of lifetime aggression: integrating cortical thickness, personality pathology and trauma exposure. | Sheehan AE et al. | β | 2021 | β |
| Evidence for the taxonic latent structure for DSM-5 intermittent explosive disorder in adults. | Fanning JR et al. | β | 2021 | β |
| Genetic Influences on the Covariance and Genetic Correlations in a Bivariate Twin Model: An Application to Well-Being. | de Vries LP et al. | β | 2021 | β |
| Is the association between childhood maltreatment and aggressive behavior mediated by hostile attribution bias in women? A discordant twin and sibling study. | Johansson A et al. | β | 2021 | β |
| Measuring Engagement in Antisocial Behavior During Late Adolescence and Early Adulthood for Typically Developing Youth. | Ogilvie JM et al. | β | 2021 | β |
| Paternal Sensitivity and Children's Cognitive and Socioemotional Outcomes: A Meta-Analytic Review. | Rodrigues M et al. | β | 2021 | β |
| Shared Genomic Architectures of COVID-19 and Antisocial Behavior | Adams CD et al. | β | 2021 | β |
| The neurobiology of human aggressive behavior: Neuroimaging, genetic, and neurochemical aspects. | Cupaioli FA et al. | β | 2021 | β |
| Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum. | Krueger RF et al. | β | 2021 | β |
| Are Owls and Larks Different When it Comes to Aggression? Genetics, Neurobiology, and Behavior. | Deibel SH et al. | β | 2020 | β |
| Child Antisocial Behavior Is more Environmental in Origin in Disadvantaged Neighborhoods: Evidence Across Residents' Perceptions and Geographic Scales in Two Samples. | Burt SA et al. | β | 2020 | β |
| Child maltreatment and the risk of antisocial behaviour: A population-based cohort study spanning 50 years. | Degli Esposti M et al. | β | 2020 | β |
| Content, diagnostic, correlational, and genetic similarities between common measures of childhood aggressive behaviors and related psychiatric traits. | Hendriks AM et al. | β | 2020 | β |
| Do neighborhood social processes moderate the etiology of youth conduct problems? | Burt SA et al. | β | 2020 | β |
| Prediction of child and adolescent outcomes with broadband and narrowband dimensions of internalizing and externalizing behavior using the child and adolescent version of the Strengths and Difficulties Questionnaire. | Kulawiak PR et al. | β | 2020 | β |
| The Genetics of Externalizing Problems. | Barr PB et al. | β | 2020 | β |
| Twin study of laboratory-induced aggression. | DiniΔ BM et al. | β | 2020 | β |
| A neurodevelopmental perspective on male violence. | Raine A | β | 2019 | β |
| Biological explanations of criminal behavior. | Ling S et al. | β | 2019 | β |
| Children Sleep and Antisocial Behavior: Differential Association of Sleep with Aggression and Rule-Breaking. | Madrid-Valero JJ et al. | β | 2019 | β |
| Comorbidity of bipolar I disorder and conduct disorder: a familial risk analysis. | Wozniak J et al. | β | 2019 | β |
| Conduct disorder. | Fairchild G et al. | β | 2019 | β |
| Genetic influences on antisocial behavior: recent advances and future directions. | Gard AM et al. | β | 2019 | β |
| How should we understand the absence of sex differences in the genetic and environmental origins of antisocial behavior? | Burt SA et al. | β | 2019 | β |
| Maladaptive Aggression: With a Focus on Impulsive Aggression in Children and Adolescents. | Connor DF et al. | β | 2019 | β |
| Mechanisms underlying social gradients in child and adolescent antisocial behaviour. | Piotrowska PJ et al. | β | 2019 | β |
| Parenting and prenatal risk as moderators of genetic influences on conduct problems during middle childhood. | Marceau K et al. | β | 2019 | β |
| Severe conduct problems in adolescence and risk of schizophrenia in early adulthood. | Manninen M et al. | β | 2019 | β |
| The validity of conduct disorder symptom profiles in high-risk male youth. | Aebi M et al. | β | 2019 | β |
| Appetitive and reactive aggression are differentially associated with the STin2 genetic variant in the serotonin transporter gene. | Hemmings SMJ et al. | β | 2018 | β |
| Are there sex differences in the etiology of youth antisocial behavior? | Burt SA et al. | β | 2018 | β |
| Callous-Unemotional Traits Moderate Genetic and Environmental Influences on Rule-Breaking and Aggression: Evidence for Gene Γ Trait Interaction. | Mann FD et al. | β | 2018 | β |
| Developmental Origins of Chronic Physical Aggression: A Bio-Psycho-Social Model for the Next Generation of Preventive Interventions. | Tremblay RE et al. | β | 2018 | β |
| Genetic influences on conduct disorder. | Salvatore JE et al. | β | 2018 | β |
| Longitudinal Analysis of Particulate Air Pollutants and Adolescent Delinquent Behavior in Southern California. | Younan D et al. | β | 2018 | β |
| Parent depressive symptomatology moderates the etiology of externalizing behavior in childhood: An examination of gene-environment interaction effects. | Clark DA et al. | β | 2018 | β |
| Sex Differences in the Genetic and Environmental Influences on Self-Reported Non-aggressive and Aggressive Conduct Disorder Symptoms in Early and Middle Adolescence. | Van Hulle CA et al. | β | 2018 | β |
| Assessing the interplay between multigenic and environmental influences on adolescent to adult pathways of antisocial behaviors. | Li JJ | β | 2017 | β |
| Blunted Ambiguity Aversion During Cost-Benefit Decisions in Antisocial Individuals. | Buckholtz JW et al. | β | 2017 | β |
| Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior. | Tielbeek JJ et al. | β | 2017 | β |
| Latent trajectories of adolescent antisocial behavior: Serotonin transporter linked polymorphic region (5-HTTLPR) genotype influences sensitivity to perceived parental support. | Tung I et al. | β | 2017 | β |
| Reciprocal Associations between Delinquent Behavior and Social Network Position during Middle School. | Andrews NCZ et al. | β | 2017 | β |
| Sum Scores in Twin Growth Curve Models: Practicality Versus Bias. | Luningham JM et al. | β | 2017 | β |
| Aggressive behavior in humans: Genes and pathways identified through association studies. | FernΓ ndez-Castillo N et al. | β | 2016 | β |
| Beyond comorbidity: Toward a dimensional and hierarchical approach to understanding psychopathology across the life span. | Forbes MK et al. | β | 2016 | β |
| Facial Affect Recognition in Violent and Nonviolent Antisocial Behavior Subtypes. | SchΓΆnenberg M et al. | β | 2016 | β |
| Genetic and Neuroimaging Features of Personality Disorders: State of the Art. | Ma G et al. | β | 2016 | β |
| Genetics of aggressive behavior: An overview. | Veroude K et al. | β | 2016 | β |
| Interacting effect of MAOA genotype and maternal prenatal smoking on aggressive behavior in young adulthood. | Hohmann S et al. | β | 2016 | β |
| Neighborhood Disadvantage Alters the Origins of Children's Nonaggressive Conduct Problems. | Burt SA et al. | β | 2016 | β |
| The Development of Comorbid Conduct Problems in Children With ADHD: An Example of an Integrative Developmental Psychopathology Perspective. | Danforth JS et al. | β | 2016 | β |
| The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms. | Waltes R et al. | β | 2016 | β |
| The Phenomenology of Non-Aggressive Antisocial Behavior During Childhood. | Burt SA et al. | β | 2016 | β |
| Warm Parenting and Effortful Control in Toddlerhood: Independent and Interactive Predictors of School-Age Externalizing Behavior. | Reuben JD et al. | β | 2016 | β |
| A Bayesian nonparametric meta-analysis model. | Karabatsos G et al. | β | 2015 | β |
| A Swedish national twin study of criminal behavior and its violent, white-collar and property subtypes. | Kendler KS et al. | β | 2015 | β |
| "Bad genes" & criminal responsibility. | GonzΓ‘lez-Tapia MI et al. | β | 2015 | β |
| Childhood EEG frontal alpha power as a predictor of adolescent antisocial behavior: a twin heritability study. | Niv S et al. | β | 2015 | β |
| Differential genetic and environmental influences on developmental trajectories of antisocial behavior from adolescence to young adulthood. | Zheng Y et al. | β | 2015 | β |
| Epidemiology, Comorbidity, and Behavioral Genetics of Antisocial Personality Disorder and Psychopathy. | Werner KB et al. | β | 2015 | β |
| Externalizing Problem Behavior in Adolescence: Dopaminergic Genes in Interaction with Peer Acceptance and Rejection. | Janssens A et al. | β | 2015 | β |
| Income gradients within child and adolescent antisocial behaviours. | Piotrowska PJ et al. | β | 2015 | β |
| Investigating genetic and environmental contributions to adolescent externalizing behavior in a collectivistic culture: a multi-informant twin study. | Chen J et al. | β | 2015 | β |
| Neighborhood as a predictor of non-aggressive, but not aggressive, antisocial behaviors in adulthood. | Burt SA et al. | β | 2015 | β |
| Paternal antisocial behavior and sons' cognitive ability: a population-based quasiexperimental study. | Latvala A et al. | β | 2015 | β |
| Socioeconomic status and antisocial behaviour among children and adolescents: a systematic review and meta-analysis. | Piotrowska PJ et al. | β | 2015 | β |
| The Expression of Genetic Risk for Aggressive and Non-aggressive Antisocial Behavior is Moderated by Peer Group Norms. | Vitaro F et al. | β | 2015 | β |
| The Return of Lombroso? Ethical Aspects of (Visions of) Preventive Forensic Screening. | Munthe C et al. | β | 2015 | β |
| A longitudinal twin study of physical aggression during early childhood: evidence for a developmentally dynamic genome. | Lacourse E et al. | β | 2014 | β |
| Brief report: Violent false memories and engagement in aggressive and delinquent behavior: an investigation in adolescents. | Vannucci M et al. | β | 2014 | β |
| Environmental transmission of violent criminal behavior in siblings: a Swedish national study. | Kendler KS et al. | β | 2014 | β |
| Examining the factor structure and etiology of prosociality. | Mikolajewski AJ et al. | β | 2014 | β |
| Exploring whether genetic differences between siblings explain sibling differences in criminal justice outcomes. | Schwartz JA et al. | β | 2014 | β |
| Parent-child conflict as an etiological moderator of childhood conduct problems: an example of a 'bioecological' gene-environment interaction. | Burt SA et al. | β | 2014 | β |
| Physiological correlates of psychopathy, antisocial personality disorder, habitual aggression, and violence. | Patrick CJ | β | 2014 | β |
| Prosocial peer affiliation suppresses genetic influences on non-aggressive antisocial behaviors during childhood. | Burt SA et al. | β | 2014 | β |
| Psychiatrists' views of the genetic bases of mental disorders and behavioral traits and their use of genetic tests. | Klitzman R et al. | β | 2014 | β |
| The 2-repeat allele of the MAOA gene confers an increased risk for shooting and stabbing behaviors. | Beaver KM et al. | β | 2014 | β |
| The etiology of the association between child antisocial behavior and maternal negativity varies across aggressive and non-aggressive rule-breaking forms of antisocial behavior. | Klahr AM et al. | β | 2014 | β |
| The role of genetic variants in genes regulating the oxytocin-vasopressin neurohumoral system in childhood-onset aggression. | Malik AI et al. | β | 2014 | β |
| A demonstration of the generalizability of twin-based research on antisocial behavior. | Barnes JC et al. | β | 2013 | β |
| A longitudinal biosocial study of cortisol and peer influence on the development of adolescent antisocial behavior. | Platje E et al. | β | 2013 | β |
| Delinquent peer affiliation as an etiological moderator of childhood delinquency. | Burt SA et al. | β | 2013 | β |
| Do etiological influences on aggression overlap with those on rule breaking? A meta-analysis. | Burt SA | β | 2013 | β |
| Evocative gene-environment correlation in the mother-child relationship: a twin study of interpersonal processes. | Klahr AM et al. | β | 2013 | β |
| Familial influences on conduct disorder reflect 2 genetic factors and 1 shared environmental factor. | Kendler KS et al. | β | 2013 | β |
| Gene-environment correlation underlying the association between parental negativity and adolescent externalizing problems. | Marceau K et al. | β | 2013 | β |
| Genes of experience: explaining the heritability of putative environmental variables through their association with behavioural and emotional traits. | McAdams TA et al. | β | 2013 | β |
| Genetic and environmental influences on antisocial behavior. | Tuvblad C et al. | β | 2013 | β |
| Is relational aggression part of the externalizing spectrum? a bifactor model of youth antisocial behavior. | Tackett JL et al. | β | 2013 | β |
| Maternal warmth and directiveness jointly moderate the etiology of childhood conduct problems. | Alexandra Burt S et al. | β | 2013 | β |
| Research review: evaluating and reformulating the developmental taxonomic theory of antisocial behaviour. | Fairchild G et al. | β | 2013 | β |
| The genetic and environmental overlap between aggressive and non-aggressive antisocial behavior in children and adolescents using the self-report delinquency interview (SR-DI). | Wang P et al. | β | 2013 | β |
| A multivariate twin study of the DSM-IV criteria for antisocial personality disorder. | Kendler KS et al. | β | 2012 | β |
| Annual research review: phenotypic and causal structure of conduct disorder in the broader context of prevalent forms of psychopathology. | Lahey BB et al. | β | 2012 | β |
| Classes of conduct disorder symptoms and their life course correlates in a US national sample. | Breslau J et al. | β | 2012 | β |
| Etiological distinctions between aggressive and non-aggressive antisocial behavior: results from a nuclear twin family model. | Burt SA et al. | β | 2012 | β |
| Gene-environment interplay in the association between pubertal timing and delinquency in adolescent girls. | Harden KP et al. | β | 2012 | β |
| Genetically influenced change in sensation seeking drives the rise of delinquent behavior during adolescence. | Harden KP et al. | β | 2012 | β |
| Heritability, assortative mating and gender differences in violent crime: results from a total population sample using twin, adoption, and sibling models. | Frisell T et al. | β | 2012 | β |
| How do we optimally conceptualize the heterogeneity within antisocial behavior? An argument for aggressive versus non-aggressive behavioral dimensions. | Burt SA | β | 2012 | β |
| Observed externalizing behavior: a developmental comparison of genetic and environmental influences across three samples. | Marceau K et al. | β | 2012 | β |
| Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. | Tielbeek JJ et al. | β | 2012 | β |
| Age-of-onset or behavioral sub-types? A prospective comparison of two approaches to characterizing the heterogeneity within antisocial behavior. | Burt SA et al. | β | 2011 | β |
| Deviant peer affiliation and antisocial behavior: interaction with Monoamine Oxidase A (MAOA) genotype. | Lee SS | β | 2011 | β |
| Gene-environment processes linking aggression, peer victimization, and the teacher-child relationship. | Brendgen M et al. | β | 2011 | β |
| Genome-wide association study of conduct disorder symptomatology. | Dick DM et al. | β | 2011 | β |
| Human aggression across the lifespan: genetic propensities and environmental moderators. | Tuvblad C et al. | β | 2011 | β |
| Migration from Mexico to the United States and conduct disorder: a cross-national study. | Breslau J et al. | β | 2011 | β |
| The neurocognition of conduct disorder behaviors: specificity to physical aggression and theft after controlling for ADHD symptoms. | Barker ED et al. | β | 2011 | β |
| Unpacking the association: Individual differences in the relation of prenatal exposure to cigarettes and disruptive behavior phenotypes. | Wakschlag LS et al. | β | 2011 | β |
| Environmental contributions to the stability of antisocial behavior over time: are they shared or non-shared? | Burt SA et al. | β | 2010 | β |
| Has biology disproved free will and moral responsibility? | AnckarsΓ€ter H | β | 2010 | β |
| Latent class analysis of antisocial behavior: interaction of serotonin transporter genotype and maltreatment. | Li JJ et al. | β | 2010 | β |
| Psychometric characteristics and clinical correlates of NEO-PI-R fearless dominance and impulsive antisociality in the Collaborative Longitudinal Personality Disorders Study. | Witt EA et al. | β | 2010 | β |
| Research Review: 'Ain't misbehavin': Towards a developmentally-specified nosology for preschool disruptive behavior. | Wakschlag LS et al. | β | 2010 | β |
| Role of executive dysfunction in predicting frequency and severity of violence. | Hancock M et al. | β | 2010 | β |
| Continuity of aggressive antisocial behavior from childhood to adulthood: The question of phenotype definition. | Hofvander B et al. | β | 2009 | β |
| Development and validation of the Subtypes of Antisocial Behavior Questionnaire. | Burt SA et al. | β | 2009 | β |
| Do aggression and rule-breaking have different interpersonal correlates? A study of antisocial behavior subtypes, negative affect, and hostile perceptions of others. | Burt SA et al. | β | 2009 | β |
| The etiological moderation of aggressive and nonaggressive antisocial behavior by age. | Burt SA et al. | β | 2009 | β |