GOLD--graphical overview of linkage disequilibrium.
paper
Cited
Public
Unavailable
- Authors
- Abecasis, G R; Cookson, W O
- Year
- 2000
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 10842743
- DOI
- 10.1093/bioinformatics/16.2.182
SUMMARY: We describe a software package that provides a graphical summary of linkage disequilibrium in human genetic data. It allows for the analysis of family data and is well suited to the analysis of dense genetic maps. AVAILABILITY: http://www.well.ox.ac.uk/asthma/GOLD CONTACT: goncalo@well.ox.ac.uk
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| Linkage disequilibrium analysis in the genetically isolated Norfolk Island population. | Bellis C et al. | β | 2008 | β |
| Linkage disequilibrium and persistence of phase in Holstein-Friesian, Jersey and Angus cattle. | de Roos AP et al. | β | 2008 | β |
| Linkage disequilibrium and signatures of selection on chromosomes 19 and 29 in beef and dairy cattle. | Prasad A et al. | β | 2008 | β |
| Linkage disequilibrium between STRPs and SNPs across the human genome. | Payseur BA et al. | β | 2008 | β |
| Linkage disequilibrium--understanding the evolutionary past and mapping the medical future. | Slatkin M | β | 2008 | β |
| Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion. | Chen Y et al. | β | 2008 | β |
| Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. | Arnaud-Lopez L et al. | β | 2008 | β |
| Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease. | Wang L et al. | β | 2008 | β |
| Promoter polymorphisms modulating HSPA5 expression may increase susceptibility to Taiwanese Alzheimer's disease. | Hsu WC et al. | β | 2008 | β |
| Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families. | Wedenoja J et al. | β | 2008 | β |
| SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. | Kollins SH et al. | β | 2008 | β |
| The MTHFD1 gene is not involved in cleft lip with or without palate onset among the Italian population. | Palmieri A et al. | β | 2008 | β |
| The 'Pokemon' (ZBTB7) Gene: No Evidence of Association with Sporadic Breast Cancer. | Salas A et al. | β | 2008 | β |
| TPH2 and TPH1: association of variants and interactions with heroin addiction. | Nielsen DA et al. | β | 2008 | β |
| Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. | Wang G et al. | β | 2008 | β |
| Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. | Chiquet BT et al. | β | 2008 | β |
| Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans. | Kovacs P et al. | β | 2008 | β |
| X-LRT: a likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design. | Zhang L et al. | β | 2008 | β |
| ABCB1 and GST polymorphisms associated with TP53 status in breast cancer. | Nordgard SH et al. | β | 2007 | β |
| Admixture and patterns of linkage disequilibrium in a free-living vertebrate population. | Slate J et al. | β | 2007 | β |
| Admixture in European Populus hybrid zones makes feasible the mapping of loci that contribute to reproductive isolation and trait differences. | Lexer C et al. | β | 2007 | β |
| A functional CD86 polymorphism associated with asthma and related allergic disorders. | Corydon TJ et al. | β | 2007 | β |
| A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. | Cargill M et al. | β | 2007 | β |
| Allelic association and recombination hotspots in the mucin gene (MUC) complex on chromosome 11p15.5. | Rousseau K et al. | β | 2007 | β |
| Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. | Straub RE et al. | β | 2007 | β |
| Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1. | Mathew SV et al. | β | 2007 | β |
| Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. | Bhatnagar V et al. | β | 2007 | β |
| Apoptotic gene analysis in idiopathic talipes equinovarus (clubfoot). | Ester AR et al. | β | 2007 | β |
| Arrayed primer extension in the "array of arrays" format: a rational approach for microarray-based SNP genotyping. | KlitΓΈ NG et al. | β | 2007 | β |
| Association analyses of NCR3 polymorphisms with P. falciparum mild malaria. | Delahaye NF et al. | β | 2007 | β |
| Association analysis of AKT1 and schizophrenia in a UK case control sample. | Norton N et al. | β | 2007 | β |
| Association analysis of genetic polymorphisms in the CDC2 gene with late-onset Alzheimer disease. | Liang X et al. | β | 2007 | β |
| Association between SNP and haplotypes in PPARGC1 and adiponectin genes and bone mineral density in Chinese nuclear families. | Zhang ZL et al. | β | 2007 | β |
| Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families. | Liu CM et al. | β | 2007 | β |
| Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism. | Loos RJ et al. | β | 2007 | β |
| Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine. | Ehringer MA et al. | β | 2007 | β |
| Association study between the TNXB locus and schizophrenia in a Japanese population. | Tochigi M et al. | β | 2007 | β |
| Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia. | Deng X et al. | β | 2007 | β |
| Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease. | Belin AC et al. | β | 2007 | β |
| A TNF region haplotype offers protection from typhoid fever in Vietnamese patients. | Dunstan SJ et al. | β | 2007 | β |
| A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. | Kanda A et al. | β | 2007 | β |
| Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia. | Ellis JA et al. | β | 2007 | β |
| Campora: a young genetic isolate in South Italy. | Colonna V et al. | β | 2007 | β |
| CETP genotypes and HDL-cholesterol phenotypes in the HERITAGE Family Study. | Spielmann N et al. | β | 2007 | β |
| CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis. | Gao X et al. | β | 2007 | β |
| Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA. | Martinelli M et al. | β | 2007 | β |
| Combining linkage data sets for meta-analysis and mega-analysis: the GAW15 rheumatoid arthritis data set. | Segurado R et al. | β | 2007 | β |
| Comparison of GIST and LAMP on the GAW15 simulated data. | Lou X et al. | β | 2007 | β |
| C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci. | Wessel J et al. | β | 2007 | β |
| CRISPLD2: a novel NSCLP candidate gene. | Chiquet BT et al. | β | 2007 | β |
| Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'. | Gaunt TR et al. | β | 2007 | β |
| Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk. | Zhang L et al. | β | 2007 | β |
| Effectiveness of in silico tagSNP selection methods: virtual analysis of the genotypes of pharmacogenetic genes. | Nam MH et al. | β | 2007 | β |
| Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression. | Kovacs P et al. | β | 2007 | β |
| Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes. | Gueorguiev M et al. | β | 2007 | β |
| Extent of linkage disequilibrium in chicken. | Aerts J et al. | β | 2007 | β |
| Family-based and case-control studies reveal no association of lipocalin-type prostaglandin D2 synthase with schizophrenia. | Ruano D et al. | β | 2007 | β |
| Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia. | Yamada K et al. | β | 2007 | β |
| Genetic association between the PRKCH gene encoding protein kinase Ceta isozyme and rheumatoid arthritis in the Japanese population. | Takata Y et al. | β | 2007 | β |
| Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. | Meyer-Lindenberg A et al. | β | 2007 | β |
| Genetic risk factors for diabetic nephropathy on chromosomes 6p and 7q identified by the set-association approach. | KankovΓ‘ K et al. | β | 2007 | β |
| Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels. | Zhang YY et al. | β | 2007 | β |
| Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. | Moffatt MF et al. | β | 2007 | β |
| Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. | Scuteri A et al. | β | 2007 | β |
| Glucocorticoid receptor polymorphisms and haplotypes associated with chronic fatigue syndrome. | Rajeevan MS et al. | β | 2007 | β |
| Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients. | Suga T et al. | β | 2007 | β |
| Haplotypic structure across the I kappa B alpha gene (NFKBIA) and association with multiple myeloma. | Spink CF et al. | β | 2007 | β |
| Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus. | Heijmans BT et al. | β | 2007 | β |
| Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. | Hayes MG et al. | β | 2007 | β |
| Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol. | GrΓΌnhage F et al. | β | 2007 | β |
| Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection. | Hennig BJ et al. | β | 2007 | β |
| Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer. | Dai Q et al. | β | 2007 | β |
| Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis. | Vieira AR et al. | β | 2007 | β |
| Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. | Gregory SG et al. | β | 2007 | β |
| Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk. | Ashley-Koch AE et al. | β | 2007 | β |
| KIR haplotype content at the allele level in 77 Northern Irish families. | Middleton D et al. | β | 2007 | β |
| Multifactor dimensionality reduction-phenomics: a novel method to capture genetic heterogeneity with use of phenotypic variables. | Mei H et al. | β | 2007 | β |
| NAT2 variation and idiopathic talipes equinovarus (clubfoot). | Hecht JT et al. | β | 2007 | β |
| No association evidence between schizophrenia and dystrobrevin-binding protein 1 (DTNBP1) in Taiwanese families. | Liu CM et al. | β | 2007 | β |
| No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases. | Bell CG et al. | β | 2007 | β |
| Non-B27 MHC associations of ankylosing spondylitis. | Sims AM et al. | β | 2007 | β |
| Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease. | Wang L et al. | β | 2007 | β |
| Peroxisome proliferator-activated receptor-delta polymorphisms are associated with physical performance and plasma lipids: the HERITAGE Family Study. | Hautala AJ et al. | β | 2007 | β |
| Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with peak bone mass in non-sedentary men: results from the Odense androgen study. | Brixen K et al. | β | 2007 | β |
| Population-based case-control association studies. | Hancock DB et al. | β | 2007 | β |
| Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus. | Khor CC et al. | β | 2007 | β |
| Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. | Willer CJ et al. | β | 2007 | β |
| Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes. | van der Slik AR et al. | β | 2007 | β |
| SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. | Jamshidi Y et al. | β | 2007 | β |
| Significant variation in haplotype block structure but conservation in tagSNP patterns among global populations. | Gu S et al. | β | 2007 | β |
| Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in recurrent major depressive disorder. | Van Den Eede F et al. | β | 2007 | β |
| Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects. | Siddiq A et al. | β | 2007 | β |
| Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimer's disease in three sample populations. | Brown AM et al. | β | 2007 | β |
| The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. | Li S et al. | β | 2007 | β |
| The null distribution of stochastic search gene suggestion: a Bayesian approach to gene mapping. | Swartz MD et al. | β | 2007 | β |
| The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophrenia. | Bakker SC et al. | β | 2007 | β |
| Tumor necrosis factor-alpha promoter polymorphism is associated with the risk of Parkinson's disease. | Wu YR et al. | β | 2007 | β |
| Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. | Rao F et al. | β | 2007 | β |
| Variants of C1GALT1 gene are associated with the genetic susceptibility to IgA nephropathy. | Li GS et al. | β | 2007 | β |
| Whole genome linkage disequilibrium maps in cattle. | McKay SD et al. | β | 2007 | β |
| A cholinergic receptor gene (CHRM2) affects event-related oscillations. | Jones KA et al. | β | 2006 | β |
| A detailed Hapmap of the Sitosterolemia locus spanning 69 kb; differences between Caucasians and African-Americans. | Pandit B et al. | β | 2006 | β |
| A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q. | Mathias RA et al. | β | 2006 | β |
| AMP-kinase alpha2 subunit gene PRKAA2 variants are associated with total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol in normal women. | Spencer-Jones NJ et al. | β | 2006 | β |
| An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. | Ashley-Koch AE et al. | β | 2006 | β |
| A quantitative trait locus for body fat on chromosome 1q43 in French Canadians: linkage and association studies. | Aissani B et al. | β | 2006 | β |
| Are molecular haplotypes worth the time and expense? A cost-effective method for applying molecular haplotypes. | Levenstien MA et al. | β | 2006 | β |
| Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach. | Gloyn AL et al. | β | 2006 | β |
| Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families. | Yang TL et al. | β | 2006 | β |
| Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes. | Proudnikov D et al. | β | 2006 | β |
| Association analysis of SOD2 variants with methamphetamine psychosis in Japanese and Taiwanese populations. | Nakamura K et al. | β | 2006 | β |
| Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura. | Fernandez F et al. | β | 2006 | β |
| Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample. | Dick DM et al. | β | 2006 | β |
| Association between non-Hodgkin lymphoma and haplotypes in the TNF region. | Spink CF et al. | β | 2006 | β |
| Association between the transforming growth factor alpha gene and nonsyndromic oral clefts: a HuGE review. | Vieira AR | β | 2006 | β |
| Association of alpha1A adrenergic receptor gene variants on chromosome 8p21 with human stage 2 hypertension. | Gu D et al. | β | 2006 | β |
| Association of DAZL haplotypes with spermatogenic failure in infertile men. | Teng YN et al. | β | 2006 | β |
| Association of interferon-gamma gene haplotype in the Chinese population with hepatitis B virus infection. | Liu M et al. | β | 2006 | β |
| Association of Reelin gene polymorphisms with autism. | Serajee FJ et al. | β | 2006 | β |
| Association of the progesterone receptor gene with breast cancer risk: a single-nucleotide polymorphism tagging approach. | Pooley KA et al. | β | 2006 | β |
| Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. | Scott LJ et al. | β | 2006 | β |
| Association of tumor necrosis factor alpha polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort. | Khanna D et al. | β | 2006 | β |
| Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study. | Onnie CM et al. | β | 2006 | β |
| Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease. | Shibata N et al. | β | 2006 | β |
| Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population. | Lin WH et al. | β | 2006 | β |
| Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia. | Shibata H et al. | β | 2006 | β |
| Association study of the dystrobrevin-binding gene with schizophrenia in Australian and Indian samples. | Holliday EG et al. | β | 2006 | β |
| Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese. | Gu D et al. | β | 2006 | β |
| A tutorial on statistical methods for population association studies. | Balding DJ | β | 2006 | β |
| Bardet-Biedl syndrome gene variants are associated with both childhood and adult common obesity in French Caucasians. | Benzinou M et al. | β | 2006 | β |
| Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents. | Hopfer CJ et al. | β | 2006 | β |
| CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. | Li M et al. | β | 2006 | β |
| Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence. | Frodsham AJ et al. | β | 2006 | β |
| Clustering of haplotypes based on phylogeny: how good a strategy for association testing? | Bardel C et al. | β | 2006 | β |
| Co-localization of susceptibility loci for psoriasis (PSORS4) and atopic dermatitis (ATOD2) on human chromosome 1q21. | Giardina E et al. | β | 2006 | β |
| Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. | Bonnycastle LL et al. | β | 2006 | β |
| Congenital heart defects and genetic variants in the methylenetetrahydroflate reductase gene. | Hobbs CA et al. | β | 2006 | β |
| Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method. | Zaykin DV et al. | β | 2006 | β |
| Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. | Suviolahti E et al. | β | 2006 | β |
| Data-mining methods as useful tools for predicting individual drug response: application to CYP2D6 data. | Sabbagh A et al. | β | 2006 | β |
| Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. | Luo X et al. | β | 2006 | β |
| Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. | Dick DM et al. | β | 2006 | β |
| Endothelin-1 gene variants and levels associate with adaptation to hypobaric hypoxia in high-altitude natives. | Rajput C et al. | β | 2006 | β |
| Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study. | Ogata T et al. | β | 2006 | β |
| Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23. | Dunn JS et al. | β | 2006 | β |
| Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. | Lin PI et al. | β | 2006 | β |
| Family based association analysis of the IL2 and IL15 genes in allergic disorders. | Christensen U et al. | β | 2006 | β |
| Family-based case-control study of MAOA and MAOB polymorphisms in Parkinson disease. | Kang SJ et al. | β | 2006 | β |
| Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1. | Wittwer J et al. | β | 2006 | β |
| GATA2 is associated with familial early-onset coronary artery disease. | Connelly JJ et al. | β | 2006 | β |
| Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. | Traherne JA et al. | β | 2006 | β |
| Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans. | BΓΆttcher Y et al. | β | 2006 | β |
| Genomewide association analysis of human narcolepsy and a new resistance gene. | Kawashima M et al. | β | 2006 | β |
| Haplotypes of the human RET proto-oncogene associated with Hirschsprung disease in the Italian population derive from a single ancestral combination of alleles. | Lantieri F et al. | β | 2006 | β |
| Haplotype structure of five SNPs within the ACE gene in the Tunisian population. | RebaΓ― M et al. | β | 2006 | β |
| Haplotypic variation in MRE11, RAD50 and NBS1 and risk of non-Hodgkin's lymphoma. | Rollinson S et al. | β | 2006 | β |
| Heart rate recovery after maximal exercise is associated with acetylcholine receptor M2 (CHRM2) gene polymorphism. | Hautala AJ et al. | β | 2006 | β |
| Human ALOX12, but not ALOX15, is associated with BMD in white men and women. | Ichikawa S et al. | β | 2006 | β |
| ICAM gene cluster SNPs and prostate cancer risk in African Americans. | Chen H et al. | β | 2006 | β |
| Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. | Greenwood TA et al. | β | 2006 | β |
| IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer. | Al-Zahrani A et al. | β | 2006 | β |
| Impact of complex genetic variation in COMT on human brain function. | Meyer-Lindenberg A et al. | β | 2006 | β |
| Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. | Collins AL et al. | β | 2006 | β |
| JLIN: a java based linkage disequilibrium plotter. | Carter KW et al. | β | 2006 | β |
| KCNQ4: a gene for age-related hearing impairment? | Van Eyken E et al. | β | 2006 | β |
| Lack of association between UBQLN1 and Alzheimer disease. | Slifer MA et al. | β | 2006 | β |
| Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions. | Drgon T et al. | β | 2006 | β |
| Linkage disequilibrium on chromosome 6 in Australian Holstein-Friesian cattle. | Khatkar MS et al. | β | 2006 | β |
| Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. | Service S et al. | β | 2006 | β |
| MIDAS: software for analysis and visualisation of interallelic disequilibrium between multiallelic markers. | Gaunt TR et al. | β | 2006 | β |
| MUC7 haplotype analysis: results from a longitudinal birth cohort support protective effect of the MUC7*5 allele on respiratory function. | Rousseau K et al. | β | 2006 | β |
| Mutation-positive and mutation-negative patients with Cowden and Bannayan-Riley-Ruvalcaba syndromes associated with distinct 10q haplotypes. | Pezzolesi MG et al. | β | 2006 | β |
| Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions. | Boyles AL et al. | β | 2006 | β |
| Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. | Law AJ et al. | β | 2006 | β |
| No association of G72 and D-amino acid oxidase genes with schizophrenia. | Liu YL et al. | β | 2006 | β |
| NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. | Hancock DB et al. | β | 2006 | β |
| Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. | Lin PI et al. | β | 2006 | β |
| Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population. | Jamshidi Y et al. | β | 2006 | β |
| Plasminogen activator inhibitor-1 gene: selection of tagging single nucleotide polymorphisms and association with coronary heart disease. | Su S et al. | β | 2006 | β |
| Polymorphisms in the bone morphogenetic protein 2 (BMP2) gene do not affect bone mineral density in white men or women. | Ichikawa S et al. | β | 2006 | β |
| Polymorphisms in the leptin and leptin receptor genes in relation to resting metabolic rate and respiratory quotient in the QuΓ©bec Family Study. | Loos RJ et al. | β | 2006 | β |
| Polymorphism within the interferon-gamma/receptor complex is associated with pulmonary tuberculosis. | Cooke GS et al. | β | 2006 | β |
| Power-based, phase-informed selection of single nucleotide polymorphisms for disease association screens. | Saccone SF et al. | β | 2006 | β |
| Predominance of interaction among wild-type alleles of CYP11B2 in Himalayan natives associates with high-altitude adaptation. | Rajput C et al. | β | 2006 | β |
| Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study. | Rodriguez-Lopez J et al. | β | 2006 | β |
| Selection of SNP subsets for association studies in candidate genes: comparison of the power of different strategies to detect single disease susceptibility locus effects. | Cousin E et al. | β | 2006 | β |
| SLC25A12 and CMYA3 gene variants are not associated with autism in the IMGSAC multiplex family sample. | Blasi F et al. | β | 2006 | β |
| Testing association between LRRK2 and Parkinson's disease and investigating linkage disequilibrium. | PaisΓ‘n-RuΓz C et al. | β | 2006 | β |
| UGT1A polymorphisms in a Swedish cohort and a human diversity panel, and the relation to bilirubin plasma levels in males and females. | Mercke Odeberg J et al. | β | 2006 | β |
| Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa. | Tosh K et al. | β | 2006 | β |
| Variation in MICA and MICB genes and enhanced susceptibility to paucibacillary leprosy in South India. | Tosh K et al. | β | 2006 | β |
| VizStruct for visualization of genome-wide SNP analyses. | Bhasi K et al. | β | 2006 | β |
| ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease. | MacΓ© S et al. | β | 2005 | β |
| ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity. | TankΓ³ LB et al. | β | 2005 | β |
| Age-associated skewing of X-inactivation ratios of blood cells in normal females: a candidate-gene analysis approach. | Chagnon P et al. | β | 2005 | β |
| A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. | Miretti MM et al. | β | 2005 | β |
| A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population. | Weedon MN et al. | β | 2005 | β |
| Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2. | Deak KL et al. | β | 2005 | β |
| Analysis of CARD15/NOD2 haplotypes fails to identify common variants associated with rheumatoid arthritis susceptibility. | Addo A et al. | β | 2005 | β |
| Analysis of the RELN gene as a genetic risk factor for autism. | Skaar DA et al. | β | 2005 | β |
| Association analysis of transcripts from the bipolar susceptibility locus on chromosome 4q35, exclusion of a pathogenic role for eight positional candidate genes. | Blair IP et al. | β | 2005 | β |
| Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD. | Park L et al. | β | 2005 | β |
| Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. | McGovern DP et al. | β | 2005 | β |
| Association between single-nucleotide polymorphisms in the SEC8L1 gene, which encodes a subunit of the exocyst complex, and rheumatoid arthritis in a Japanese population. | Hamada D et al. | β | 2005 | β |
| Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease. | Noureddine MA et al. | β | 2005 | β |
| Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity. | Bell CG et al. | β | 2005 | β |
| Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. | Zhang Y et al. | β | 2005 | β |
| Association of the TSHR gene with Graves' disease: the first disease specific locus. | Dechairo BM et al. | β | 2005 | β |
| Association study of CREB1 and childhood-onset mood disorders. | Burcescu I et al. | β | 2005 | β |
| A synonymous coding polymorphism in the alpha2-Heremans-schmid glycoprotein gene is associated with type 2 diabetes in French Caucasians. | Siddiq A et al. | β | 2005 | β |
| A variant in the CD209 promoter is associated with severity of dengue disease. | Sakuntabhai A et al. | β | 2005 | β |
| Beta(2)-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics*. | Kukreti R et al. | β | 2005 | β |
| Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium. | Goode EL et al. | β | 2005 | β |
| Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: evidence of association at GRIN2A and ABAT. | Barnby G et al. | β | 2005 | β |
| CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study. | Luo X et al. | β | 2005 | β |
| Chromosome 11-q24 region in Tourette syndrome: association and linkage disequilibrium study in the French Canadian population. | DΓaz-AnzaldΓΊa A et al. | β | 2005 | β |
| Common polymorphisms in the USF1 gene are not associated with type 2 diabetes in French Caucasians. | Gibson F et al. | β | 2005 | β |
| Comparison of genotype- and haplotype-based approaches for fine-mapping of alcohol dependence using COGA data. | Pinnaduwage D et al. | β | 2005 | β |
| Contribution of the LRP5 gene to normal variation in peak BMD in women. | Koller DL et al. | β | 2005 | β |
| DCDC2 is associated with reading disability and modulates neuronal development in the brain. | Meng H et al. | β | 2005 | β |
| Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene. | Ertekin-Taner N et al. | β | 2005 | β |
| Evaluation of linkage disequilibrium and its effect on non-parametric multipoint linkage analysis using two high density single-nucleotide polymorphism mapping panels. | Murray SS | β | 2005 | β |
| Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population. | Swanson DA et al. | β | 2005 | β |
| Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease. | Burns JC et al. | β | 2005 | β |
| GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss. | Addington AM et al. | β | 2005 | β |
| Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes. | Bagwell AM et al. | β | 2005 | β |
| Genetic analysis of the maximum drinks phenotype. | Saccone SF et al. | β | 2005 | β |
| Genetic and genomic studies of PADI4 in rheumatoid arthritis. | Harney SM et al. | β | 2005 | β |
| Genetic modifiers of lung disease in cystic fibrosis. | Drumm ML et al. | β | 2005 | β |
| Genetic study of ICAM1 in clinical malaria in Senegal. | Ndiaye R et al. | β | 2005 | β |
| Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. | Iwasaki N et al. | β | 2005 | β |
| Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. | Hillmer AM et al. | β | 2005 | β |
| Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers. | Abecasis GR et al. | β | 2005 | β |
| Haplotypes and haplotype-tagging single-nucleotide polymorphism: presentation Group 8 of Genetic Analysis Workshop 14. | Beckmann L et al. | β | 2005 | β |
| Haplotypes in the tumour necrosis factor region and myeloma. | Morgan GJ et al. | β | 2005 | β |
| Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. | Newhouse SJ et al. | β | 2005 | β |
| Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia. | Sanders AR et al. | β | 2005 | β |
| HLA antigens in Greek children with allergic bronchial asthma. | Parapanissiou E et al. | β | 2005 | β |
| Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4. | Glaser B et al. | β | 2005 | β |
| Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. | Oliveira SA et al. | β | 2005 | β |
| Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. | Ma DQ et al. | β | 2005 | β |
| Identifying nineteenth century genealogical links from genotypes. | Stankovich J et al. | β | 2005 | β |
| Increased level of linkage disequilibrium in rural compared with urban communities: a factor to consider in association-study design. | Vitart V et al. | β | 2005 | β |
| Inferring haplotypes at the NAT2 locus: the computational approach. | Sabbagh A et al. | β | 2005 | β |
| Interferon regulatory factor-6: a gene predisposing to isolated cleft lip with or without cleft palate in the Belgian population. | GhassibΓ© M et al. | β | 2005 | β |
| Introduction to statistical analysis of population data in immunogenetics. | Gourraud PA et al. | β | 2005 | β |
| Linkage and association analyses of microsatellites and single-nucleotide polymorphisms in nuclear families. | Lin J et al. | β | 2005 | β |
| Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape. | Coussens AK et al. | β | 2005 | β |
| Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356. | Glaser B et al. | β | 2005 | β |
| Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population. | Nilsson-Ardnor S et al. | β | 2005 | β |
| Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR. | Helms C et al. | β | 2005 | β |
| Malic enzyme 2 may underlie susceptibility to adolescent-onset idiopathic generalized epilepsy. | Greenberg DA et al. | β | 2005 | β |
| Molecular evolution of the sheep prion protein gene. | Slate J | β | 2005 | β |
| Mutation screen and association study of EZH2 as a susceptibility gene for aggressive prostate cancer. | Bachmann N et al. | β | 2005 | β |
| No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. | Dick DM et al. | β | 2005 | β |
| NOD1 variation, immunoglobulin E and asthma. | Hysi P et al. | β | 2005 | β |
| No evidence for association between polymorphisms in GRM3 and schizophrenia. | Norton N et al. | β | 2005 | β |
| Novel IL-6 haplotypes and disease association. | Fife MS et al. | β | 2005 | β |
| On the use of haplotype phylogeny to detect disease susceptibility loci. | Bardel C et al. | β | 2005 | β |
| Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10. | Hayes MG et al. | β | 2005 | β |
| Platelet glycoprotein I(b)alpha and integrin alpha2 beta1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel. | Di Paola J et al. | β | 2005 | β |
| Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomas. | Yang P et al. | β | 2005 | β |
| Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women. | Ichikawa S et al. | β | 2005 | β |
| Positional identification of an asthma susceptibility gene on human chromosome 5q33. | Noguchi E et al. | β | 2005 | β |
| Power and sample size calculations for genetic case/control studies using gene-centric SNP maps: application to human chromosomes 6, 21, and 22 in three populations. | De La Vega FM et al. | β | 2005 | β |
| Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population. | Spencer-Jones NJ et al. | β | 2005 | β |
| PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. | Carlton VE et al. | β | 2005 | β |
| Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. | Beuten J et al. | β | 2005 | β |
| Single-point haplotype scores telomeric to human leukocyte antigen-C give a high susceptibility major histocompatibility complex haplotype for psoriasis in a Caucasian population. | Lench N et al. | β | 2005 | β |
| SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. | Lin Z et al. | β | 2005 | β |
| SNPAnalyzer: a web-based integrated workbench for single-nucleotide polymorphism analysis. | Yoo J et al. | β | 2005 | β |
| SNP selection for association studies: maximizing power across SNP choice and study size. | Pardi F et al. | β | 2005 | β |
| SNPs in the neural cell adhesion molecule 1 gene (NCAM1) may be associated with human neural tube defects. | Deak KL et al. | β | 2005 | β |
| Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population. | Scapoli L et al. | β | 2005 | β |
| Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus. | Benayed R et al. | β | 2005 | β |
| Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris. | HΓΌffmeier U et al. | β | 2005 | β |
| TaqMan assays for genotyping of single nucleotide polymorphisms present at a disease susceptibility locus on chromosome 6. | Koch W et al. | β | 2005 | β |
| The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region. | Barreiro LB et al. | β | 2005 | β |
| The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. | Ng MC et al. | β | 2005 | β |
| The presence of tandem endothelial nitric oxide synthase gene polymorphisms identifying brain aneurysms more prone to rupture. | Khurana VG et al. | β | 2005 | β |
| TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso. | Flori L et al. | β | 2005 | β |
| Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population. | Orloff MS et al. | β | 2005 | β |
| Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. | Callicott JH et al. | β | 2005 | β |
| Variation in IRF6 contributes to nonsyndromic cleft lip and palate. | Blanton SH et al. | β | 2005 | β |
| WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic. | Turner ST et al. | β | 2005 | β |
| Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci. | Kim U et al. | β | 2005 | β |
| X-chromosome as a marker for population history: linkage disequilibrium and haplotype study in Eurasian populations. | Laan M et al. | β | 2005 | β |
| A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. | Francks C et al. | β | 2004 | β |
| A highly informative SNP linkage panel for human genetic studies. | Murray SS et al. | β | 2004 | β |
| A linkage disequilibrium map of the 1-Mb 15q12 GABA(A) receptor subunit cluster and association to autism. | McCauley JL et al. | β | 2004 | β |
| Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes. | Rabionet R et al. | β | 2004 | β |
| Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. | Liew CF et al. | β | 2004 | β |
| An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population. | Noguchi E et al. | β | 2004 | β |
| Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity. | Schmidt H et al. | β | 2004 | β |
| A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. | Nyholt DR | β | 2004 | β |
| Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts. | Yamada K et al. | β | 2004 | β |
| Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromosome 10 and Alzheimer's disease. | Riemenschneider M et al. | β | 2004 | β |
| Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma. | Fukai H et al. | β | 2004 | β |
| Association between evolutionary history of angiotensinogen haplotypes and plasma levels. | Fejerman L et al. | β | 2004 | β |
| Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection. | Deng G et al. | β | 2004 | β |
| Association of GABRG3 with alcohol dependence. | Dick DM et al. | β | 2004 | β |
| Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses. | Riechman SE et al. | β | 2004 | β |
| Association of neural cell adhesion molecule 1 gene polymorphisms with bipolar affective disorder in Japanese individuals. | Arai M et al. | β | 2004 | β |
| Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. | Bento JL et al. | β | 2004 | β |
| Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease. | Sharan K et al. | β | 2004 | β |
| Association of tryptophan 2,3 dioxygenase gene polymorphism with autism. | Nabi R et al. | β | 2004 | β |
| Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology. | Wen G et al. | β | 2004 | β |
| Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population. | Weedon MN et al. | β | 2004 | β |
| Common variants within the interleukin 4 receptor alpha gene (IL4R) are associated with susceptibility to osteoarthritis. | Forster T et al. | β | 2004 | β |
| Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene. | Nejentsev S et al. | β | 2004 | β |
| Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. | Nicodemus KK et al. | β | 2004 | β |
| Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus. | Lappalainen J et al. | β | 2004 | β |
| Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome. | Schulze TG et al. | β | 2004 | β |
| Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population. | Tsai HJ et al. | β | 2004 | β |
| Effect of sex and haplotype on plasma tryptase levels in healthy adults. | Min HK et al. | β | 2004 | β |
| Endogenous opioid receptor genes and alcohol dependence among Taiwanese Han. | Loh el W et al. | β | 2004 | β |
| Ethnic differences in the linkage disequilibrium and distribution of single-nucleotide polymorphisms in 35 candidate genes for cardiovascular diseases. | Ng MC et al. | β | 2004 | β |
| Evidence for a cluster of genes on chromosome 17q11-q21 controlling susceptibility to tuberculosis and leprosy in Brazilians. | Jamieson SE et al. | β | 2004 | β |
| Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p. | Brintnell W et al. | β | 2004 | β |
| Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus. | Barreto M et al. | β | 2004 | β |
| Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor and panic disorder. | Hamilton SP et al. | β | 2004 | β |
| Examination of candidate genes in language disorder: a model of genetic association for treatment studies. | Haines J et al. | β | 2004 | β |
| Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes. | Hutcheson HB et al. | β | 2004 | β |
| Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis. | Rubio JP et al. | β | 2004 | β |
| Extended linkage disequilibrium surrounding the hemoglobin E variant due to malarial selection. | Ohashi J et al. | β | 2004 | β |
| Failure to confirm association between AKT1 haplotype and schizophrenia in a Japanese case-control population. | Ohtsuki T et al. | β | 2004 | β |
| Family-based association study of schizophrenia with 444 markers and analysis of a new susceptibility locus mapped to 11q13.3. | Yamada K et al. | β | 2004 | β |
| Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. | van der Walt JM et al. | β | 2004 | β |
| Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33. | Chen YS et al. | β | 2004 | β |
| Genetic isolates in Corsica (France): linkage disequilibrium extension analysis on the Xq13 region. | Latini V et al. | β | 2004 | β |
| Genetics and visceral leishmaniasis in the Sudan: seeking a link. | Blackwell JM et al. | β | 2004 | β |
| Genetics of the APM1 locus and its contribution to type 2 diabetes susceptibility in French Caucasians. | Gibson F et al. | β | 2004 | β |
| Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease. | Ertekin-Taner N et al. | β | 2004 | β |
| Genetic variation in COL17A1 and the development of bullous pemphigoid. | Winsey S et al. | β | 2004 | β |
| Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. | Silander K et al. | β | 2004 | β |
| Genomic profiling of interpopulation diversity guides prioritization of candidate-genes for autoimmunity. | Grossman I et al. | β | 2004 | β |
| Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies. | Zhang K et al. | β | 2004 | β |
| Haplotype block structures show significant variation among populations. | Liu N et al. | β | 2004 | β |
| Haplotype mapping of the bronchiolitis susceptibility locus near IL8. | Hull J et al. | β | 2004 | β |
| Influence of LRP5 polymorphisms on normal variation in BMD. | Koay MA et al. | β | 2004 | β |
| Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families. | Holm P et al. | β | 2004 | β |
| Interaction between RANKL and HLA-DRB1 genotypes may contribute to younger age at onset of seropositive rheumatoid arthritis in an inception cohort. | Wu H et al. | β | 2004 | β |
| Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case-control study. | Walley AJ et al. | β | 2004 | β |
| Investigation of polymorphisms in the CREM gene in panic disorder. | Hamilton SP et al. | β | 2004 | β |
| Investigation of serotonin-related genes in antidepressant response. | Peters EJ et al. | β | 2004 | β |
| Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene. | Orlacchio A et al. | β | 2004 | β |
| Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism. | McCauley JL et al. | β | 2004 | β |
| Linkage disequilibrium and association of MAPT H1 in Parkinson disease. | Skipper L et al. | β | 2004 | β |
| Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype. | Oliveira SA et al. | β | 2004 | β |
| Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22. | Brzustowicz LM et al. | β | 2004 | β |
| Linkage disequilibrium maps constructed with common SNPs are useful for first-pass disease association screens. | Taillon-Miller P et al. | β | 2004 | β |
| Maternal transmission disequilibrium of the glutamate receptor GRIK2 in schizophrenia. | Bah J et al. | β | 2004 | β |
| Mutation history of the roma/gypsies. | Morar B et al. | β | 2004 | β |
| Neither single-marker nor haplotype analyses support an association between genetic variation near NOTCH4 and bipolar disorder. | Prathikanti S et al. | β | 2004 | β |
| No association between the APOE gene and autism. | Raiford KL et al. | β | 2004 | β |
| No evidence for linkage or association of neuregulin-1 (NRG1) with disease in the Irish study of high-density schizophrenia families (ISHDSF). | Thiselton DL et al. | β | 2004 | β |
| Polymorphic variation in the CBLB gene in human type 1 diabetes. | Kosoy R et al. | β | 2004 | β |
| Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified. | Addington AM et al. | β | 2004 | β |
| Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. | Duan J et al. | β | 2004 | β |
| Polymorphisms in xenobiotic metabolism genes and autism. | Serajee FJ et al. | β | 2004 | β |
| Positional identification of hypertension susceptibility genes on chromosome 2. | Barkley RA et al. | β | 2004 | β |
| Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen. | Timmann C et al. | β | 2004 | β |
| Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. | Yuferov V et al. | β | 2004 | β |
| Refinement of the 6p21.3 quantitative trait locus influencing dyslexia: linkage and association analyses. | Deffenbacher KE et al. | β | 2004 | β |
| Single nucleotide polymorphism screening and association analysis--exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthma. | Vollmert C et al. | β | 2004 | β |
| Susceptibility to leprosy is associated with PARK2 and PACRG. | Mira MT et al. | β | 2004 | β |
| TCR beta polymorphisms and multiple sclerosis. | Dyment DA et al. | β | 2004 | β |
| The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. | Wang E et al. | β | 2004 | β |
| The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. | Osawa H et al. | β | 2004 | β |
| The impact of SNP density on fine-scale patterns of linkage disequilibrium. | Ke X et al. | β | 2004 | β |
| The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. | Timms AE et al. | β | 2004 | β |
| Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level. | Kurreeman FA et al. | β | 2004 | β |
| Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. | Egan MF et al. | β | 2004 | β |
| Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. | Edenberg HJ et al. | β | 2004 | β |
| A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. | Bray NJ et al. | β | 2003 | β |
| Analysis of reelin as a candidate gene for autism. | Bonora E et al. | β | 2003 | β |
| Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease. | Negoro K et al. | β | 2003 | β |
| Association of erosive hand osteoarthritis with a single nucleotide polymorphism on the gene encoding interleukin-1 beta. | Stern AG et al. | β | 2003 | β |
| Association of INPP1, PIK3CG, and TSC2 gene variants with autistic disorder: implications for phosphatidylinositol signalling in autism. | Serajee FJ et al. | β | 2003 | β |
| Association of specific language impairment (SLI) to the region of 7q31. | O'Brien EK et al. | β | 2003 | β |
| CD36 polymorphism is associated with protection from cerebral malaria. | Omi K et al. | β | 2003 | β |
| Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate. | Jezewski PA et al. | β | 2003 | β |
| Dense linkage disequilibrium mapping in the 15q11-q13 maternal expression domain yields evidence for association in autism. | Nurmi EL et al. | β | 2003 | β |
| Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome. | Monti LD et al. | β | 2003 | β |
| Estimation of linkage disequilibrium in a sample of the United Kingdom dairy cattle population using unphased genotypes. | Tenesa A et al. | β | 2003 | β |
| Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. | Ertekin-Taner N et al. | β | 2003 | β |
| Genotype frequencies and linkage disequilibrium in the CEPH human diversity panel for variants in folate pathway genes MTHFR, MTHFD, MTRR, RFC1, and GCP2. | Shi M et al. | β | 2003 | β |
| Haplotype information and linkage disequilibrium mapping for single nucleotide polymorphisms. | Lu X et al. | β | 2003 | β |
| Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). | Edland SD et al. | β | 2003 | β |
| Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in the Gambia. | Aucan C et al. | β | 2003 | β |
| LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta. | Traherne JA et al. | β | 2003 | β |
| Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder. | Ranade SS et al. | β | 2003 | β |
| Linkage disequilibrium analysis of the human adenosine deaminase (ada) gene provides evidence for a lack of correlation between hot spots of equal and unequal homologous recombination. | Cruciani F et al. | β | 2003 | β |
| No evidence of type 1 diabetes susceptibility genes in the region centromeric of the HLA complex. | Johansson S et al. | β | 2003 | β |
| Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels. | Ahmadi KR et al. | β | 2003 | β |
| Patterns of linkage disequilibrium in mitochondrial DNA of 16 ruminant populations. | Slate J et al. | β | 2003 | β |
| Phenotypic heterogeneity and associations of two aldose reductase gene polymorphisms with nephropathy and retinopathy in type 2 diabetes. | Wang Y et al. | β | 2003 | β |
| Polymorphisms in the 5'-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression. | Duan J et al. | β | 2003 | β |
| Positional cloning of a novel gene influencing asthma from chromosome 2q14. | Allen M et al. | β | 2003 | β |
| Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. | Zhang Y et al. | β | 2003 | β |
| Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene. | Bacchelli E et al. | β | 2003 | β |
| The metabotropic glutamate receptor 8 gene at 7q31: partial duplication and possible association with autism. | Serajee FJ et al. | β | 2003 | β |
| Titin is a candidate gene for stroke volume response to endurance training: the HERITAGE Family Study. | Rankinen T et al. | β | 2003 | β |
| Variants of the CD40 ligand gene are not associated with increased susceptibility to tuberculosis in West Africa. | Campbell SJ et al. | β | 2003 | β |
| Variation in the protocadherin gamma A gene cluster. | Kirov G et al. | β | 2003 | β |
| A first-generation linkage disequilibrium map of human chromosome 22. | Dawson E et al. | β | 2002 | β |
| A linkage disequilibrium study of bipolar disorder and microsatellite markers on 22q13. | Liang SG et al. | β | 2002 | β |
| Association between TNFA polymorphism and the development of asthma in the Japanese population. | Noguchi E et al. | β | 2002 | β |
| Association of angiotensin-converting enzyme polymorphisms with systemic lupus erythematosus and nephritis: analysis of 644 SLE families. | Parsa A et al. | β | 2002 | β |
| Association of low-density lipoprotein receptor polymorphisms and outcome of hepatitis C infection. | Hennig BJ et al. | β | 2002 | β |
| Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. | Van Eerdewegh P et al. | β | 2002 | β |
| Caution on pedigree haplotype inference with software that assumes linkage equilibrium. | Schaid DJ et al. | β | 2002 | β |
| Evidence for linkage and association with reading disability on 6p21.3-22. | Kaplan DE et al. | β | 2002 | β |
| Finer linkage mapping of a primary hip osteoarthritis susceptibility locus on chromosome 6. | Loughlin J et al. | β | 2002 | β |
| Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis. | Rubio JP et al. | β | 2002 | β |
| Haplotype and linkage disequilibrium architecture for human cancer-associated genes. | Bonnen PE et al. | β | 2002 | β |
| High-density genotyping and linkage disequilibrium in the human genome using chromosome 22 as a model. | Remm M et al. | β | 2002 | β |
| Linkage disequilibrium in domestic sheep. | McRae AF et al. | β | 2002 | β |
| New insights into the role of thyroid hormone in the CNS: the microglial track. | Mallat M et al. | β | 2002 | β |
| Segmental linkage disequilibrium within the dopamine transporter gene. | Greenwood TA et al. | β | 2002 | β |
| TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E. | Koch W et al. | β | 2002 | β |
| The impact of genotyping error on haplotype reconstruction and frequency estimation. | Kirk KM et al. | β | 2002 | β |
| Extent and distribution of linkage disequilibrium in three genomic regions. | Abecasis GR et al. | β | 2001 | β |
| Haplotypes of the 5' region of the IL-4 gene and SNPs in the intergene sequence between the IL-4 and IL-13 genes are associated with atopic asthma. | Noguchi E et al. | β | 2001 | β |
| Identification of novel polymorphisms in the beta7 integrin gene: family-based association studies in inflammatory bowel disease. | van Heel DA et al. | β | 2001 | β |
| Short tandem repeat (STR) haplotypes in HLA: an integrated 50-kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region. | Vorechovsky I et al. | β | 2001 | β |
| Testing for gene-gene interaction controlling total IgE in families from Barbados: evidence of sensitivity regarding linkage heterogeneity among families. | Barnes KC et al. | β | 2001 | β |
| Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association. | Tsai HJ et al. | β | 2001 | β |