Stability of genetic and environmental influences on P300 amplitude: a longitudinal study in adolescent twins.
paper
Cited
Public
Unavailable
- Authors
- van Beijsterveldt, C E; van Baal, G C; Molenaar, P C; Boomsma, D I; de Geus, E J
- Year
- 2001
- Journal
- Behavior genetics
- PMID
- 11838531
- DOI
- 10.1023/a:1013389226795
This study examined the stability of genetic and environmental influences on individual differences in P300 amplitude during adolescence. The P300 component is an event-related brain potential (ERP) that has attracted much attention as a biological marker for disturbed cognitive processing in psychopathology. Understanding the genetics of this biological marker may contribute to understanding the genetics of the associated psychopathologies. In a group of 213 adolescent twin pairs, the P300 component was measured twice, the first time at age 16 and the second time 18 months later. A large part of the variance of the P300 amplitude could be explained by familial factors, with estimates ranging from 30% to 81%. Whether the familial resemblance was due to genetic or shared environmental factors depended on sex. For males, genetic factors explained familial resemblance in P300 amplitude, but for females such resemblance was likely due to shared environmental factors. The phenotypic stability of the P300 amplitude from 16 to 18 years was high in both sexes, and stability could be attributed largely to the same familial factors. There was no evidence that new familial influences emerged at age 18.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Reliability modelling of resting-state functional connectivity. | Teeuw J et al. | — | 2021 | → |
| P300 development from infancy to adolescence. | Riggins T et al. | — | 2020 | → |
| Genetic and environmental influences on functional connectivity within and between canonical cortical resting-state networks throughout adolescent development in boys and girls. | Teeuw J et al. | — | 2019 | → |
| The EMIF-AD PreclinAD study: study design and baseline cohort overview. | Konijnenberg E et al. | — | 2018 | → |
| Genetic correlates of the development of theta event related oscillations in adolescents and young adults. | Chorlian DB et al. | — | 2017 | → |
| Twin metabolomics: the key to unlocking complex phenotypes in nutrition research. | Barron R et al. | — | 2016 | → |
| Event-related potential and time-frequency endophenotypes for schizophrenia and psychotic bipolar disorder. | Ethridge LE et al. | — | 2015 | → |
| Gender modulates the development of theta event related oscillations in adolescents and young adults. | Chorlian DB et al. | — | 2015 | → |
| Genetic Sources of Subcomponents of Event-Related Potential in the Dimension of Psychosis Analyzed From the B-SNIP Study. | Narayanan B et al. | — | 2015 | → |
| Heritability and molecular-genetic basis of the P3 event-related brain potential: a genome-wide association study. | Malone SM et al. | — | 2014 | → |
| Biomarkers of bipolar disorder: specific or shared with schizophrenia? | Bellivier F et al. | — | 2013 | → |
| Family history of psychosis moderates early auditory cortical response abnormalities in non-psychotic bipolar disorder. | Hamm JP et al. | — | 2013 | → |
| Genetic influences on composite neural activations supporting visual target identification. | Ethridge LE et al. | — | 2013 | → |
| The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection. | Willemsen G et al. | — | 2013 | → |
| Event-Related Oscillations in Alcoholism Research: A Review. | Pandey AK et al. | — | 2012 | → |
| Genetic association study of the P300 endophenotype in schizophrenia. | Decoster J et al. | — | 2012 | → |
| Neural activations during auditory oddball processing discriminating schizophrenia and psychotic bipolar disorder. | Ethridge LE et al. | — | 2012 | → |
| Psychopathic traits and physiological responses to aversive stimuli in children aged 9-11 years. | Wang P et al. | — | 2012 | → |
| The P300 event-related brain potential as a neurobiological endophenotype for substance use disorders: a meta-analytic investigation. | Euser AS et al. | — | 2012 | → |
| A longitudinal twin study of effects of adolescent alcohol abuse on the neurophysiology of attention and orienting. | Koskinen SM et al. | — | 2011 | → |
| Developmental Endophenotypes: Indexing Genetic Risk for Substance Abuse with the P300 Brain Event-Related Potential. | Iacono WG et al. | — | 2011 | → |
| [Electrophysiology and schizophrenic vulnerability: the P300 component as endophenotype candidate?]. | Cermolacce M et al. | — | 2011 | → |
| A cognitive model for the intergenerational transference of alcohol use behavior. | Campbell JM et al. | — | 2010 | → |
| Genetic contribution to individual variation in binocular rivalry rate. | Miller SM et al. | — | 2010 | → |
| Heritability of head size in Dutch and Australian twin families at ages 0-50 years. | Smit DJ et al. | — | 2010 | → |
| The P300 as a possible endophenotype for schizophrenia and bipolar disorder: Evidence from twin and patient studies. | Bestelmeyer PE et al. | — | 2009 | → |
| The psychoses: cluster 3 of the proposed meta-structure for DSM-V and ICD-11. | Carpenter WT et al. | — | 2009 | → |
| Deviant P300 amplitude development in males is associated with paternal externalizing psychopathology. | Carlson SR et al. | — | 2008 | → |
| Molecular genetics of alcohol dependence and related endophenotypes. | Strat YL et al. | — | 2008 | → |
| Neurophysiological endophenotypes across bipolar and schizophrenia psychosis. | Thaker GK | — | 2008 | → |
| QTLs identified for P3 amplitude in a non-clinical sample: importance of neurodevelopmental and neurotransmitter genes. | Wright MJ et al. | — | 2008 | → |
| Application of electroencephalography to the study of cognitive and brain functions in schizophrenia. | van der Stelt O et al. | — | 2007 | → |
| Genetic contributions to long-range temporal correlations in ongoing oscillations. | Linkenkaer-Hansen K et al. | — | 2007 | → |
| Genetic contribution to the P3 in young and middle-aged adults. | Smit DJ et al. | — | 2007 | → |
| Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. | Turetsky BI et al. | — | 2007 | → |
| The different origins of stability and change in antisocial personality disorder symptoms. | Burt SA et al. | — | 2007 | → |
| Association of DRD4 exon III polymorphism with auditory P300 amplitude in 8-year-old children. | Vogel CI et al. | — | 2006 | → |
| Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism. | Kamarajan C et al. | — | 2006 | → |
| Heritability and reliability of P300, P50 and duration mismatch negativity. | Hall MH et al. | — | 2006 | → |
| Heritability of P300 amplitude development from adolescence to adulthood. | Carlson SR et al. | — | 2006 | → |
| Netherlands Twin Register: from twins to twin families. | Boomsma DI et al. | — | 2006 | → |
| Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. | Yoon HH et al. | — | 2006 | → |
| Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task. | Kamarajan C et al. | — | 2005 | → |
| Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthood. | Habeych ME et al. | — | 2005 | → |
| Etiological contributions to heavy drinking from late adolescence to young adulthood. | King SM et al. | — | 2005 | → |
| Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism. | Kamarajan C et al. | — | 2005 | → |
| Genetics of human prefrontal function. | Winterer G et al. | — | 2003 | → |
| Substance use disorders, externalizing psychopathology, and P300 event-related potential amplitude. | Iacono WG et al. | — | 2003 | → |
| Genetic analysis of IQ, processing speed and stimulus-response incongruency effects. | Posthuma D et al. | — | 2002 | → |
| Genetic sources of covariation among P3(00) and online performance variables in a delayed-response working memory task. | Wright MJ et al. | — | 2002 | → |
| P300 amplitude in adolescent twins discordant and concordant for alcohol use disorders. | Carlson SR et al. | — | 2002 | → |
| Twin and family studies of the human electroencephalogram: a review and a meta-analysis. | van Beijsterveldt CE et al. | — | 2002 | → |