Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.
paper
Cited
Public
Unavailable
- Authors
- Shigemoto, R; Kinoshita, A; Wada, E; Nomura, S; Ohishi, H; Takada, M; Flor, P J; Neki, A; Abe, T; Nakanishi, S; Mizuno, N
- Year
- 1997
- Journal
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- PMID
- 9295396
- DOI
- 10.1523/JNEUROSCI.17-19-07503.1997
- PMCID
- PMC6573434
Neurotransmission in the hippocampus is modulated variously through presynaptic metabotropic glutamate receptors (mGluRs). To establish the precise localization of presynaptic mGluRs in the rat hippocampus, we used subtype-specific antibodies for eight mGluRs (mGluR1-mGluR8) for immunohistochemistry combined with lesioning of the three major hippocampal pathways: the perforant path, mossy fiber, and Schaffer collateral. Immunoreactivity for group II (mGluR2) and group III (mGluR4a, mGluR7a, mGluR7b, and mGluR8) mGluRs was predominantly localized to presynaptic elements, whereas that for group I mGluRs (mGluR1 and mGluR5) was localized to postsynaptic elements. The medial perforant path was strongly immunoreactive for mGluR2 and mGluR7a throughout the hippocampus, and the lateral perforant path was prominently immunoreactive for mGluR8 in the dentate gyrus and CA3 area. The mossy fiber was labeled for mGluR2, mGluR7a, and mGluR7b, whereas the Schaffer collateral was labeled only for mGluR7a. Electron microscopy further revealed the spatial segregation of group II and group III mGluRs within presynaptic elements. Immunolabeling for the group III receptors was predominantly observed in presynaptic active zones of asymmetrical and symmetrical synapses, whereas that for the group II receptor (mGluR2) was found in preterminal rather than terminal portions of axons. Target cell-specific segregation of receptors, first reported for mGluR7a (Shigemoto et al,., 1996), was also apparent for the other group III mGluRs, suggesting that transmitter release is differentially regulated by 2-amino-4-phosphonobutyrate-sensitive mGluRs in individual synapses on single axons according to the identity of postsynaptic neurons.
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| The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies. | Senter RK et al. | β | 2016 | β |
| Differential expression of metabotropic glutamate and GABA receptors at neocortical glutamatergic and GABAergic axon terminals. | Bragina L et al. | β | 2015 | β |
| Functional Dissociation of Group III Metabotropic Glutamate Receptors Revealed by Direct Comparison between the Behavioral Profiles of Knockout Mouse Lines. | Goddyn H et al. | β | 2015 | β |
| Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with spatial memory status in aging rat models. | MΓ©nard C et al. | β | 2015 | β |
| Group I metabotropic glutamate receptors: a potential target for regulation of proliferation and differentiation of an immortalized human neural stem cell line. | Erichsen JL et al. | β | 2015 | β |
| Induction of Anti-Hebbian LTP in CA1 Stratum Oriens Interneurons: Interactions between Group I Metabotropic Glutamate Receptors and M1 Muscarinic Receptors. | Le Duigou C et al. | β | 2015 | β |
| In the grey zone between epilepsy and schizophrenia: alterations in group II metabotropic glutamate receptors. | Dedeurwaerdere S et al. | β | 2015 | β |
| Kv1.2 mediates heterosynaptic modulation of direct cortical synaptic inputs in CA3 pyramidal cells. | Hyun JH et al. | β | 2015 | β |
| Large intercalated neurons of amygdala relay noxious sensory information. | Bienvenu TC et al. | β | 2015 | β |
| 'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII. | Jarius S et al. | β | 2015 | β |
| Metabotropic glutamate receptor 3 is downregulated and its expression is shifted from neurons to astrocytes in the mouse lateral septum during the postpartum period. | Zhao C et al. | β | 2015 | β |
| Metabotropic glutamate receptor-mediated cyclic ADP ribose signalling. | Kaar A et al. | β | 2015 | β |
| Metabotropic glutamate receptors promote disinhibition of olfactory bulb glomeruli that scales with input strength. | Zak JD et al. | β | 2015 | β |
| Neuroprotective effects of the allosteric agonist of metabotropic glutamate receptor 7 AMN082 on oxygen-glucose deprivation- and kainate-induced neuronal cell death. | Domin H et al. | β | 2015 | β |
| Novel metabotropic glutamate receptor 4 and glutamate receptor 8 therapeutics for the treatment of anxiety. | Raber J et al. | β | 2015 | β |
| Proximodistal structure of theta coordination in the dorsal hippocampus of epileptic rats. | Laurent F et al. | β | 2015 | β |
| Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. | Yang B et al. | β | 2015 | β |
| Regulation of neuronal communication by G protein-coupled receptors. | Huang Y et al. | β | 2015 | β |
| Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity. | Trimmer JS | β | 2015 | β |
| Therapeutic potential of mGluR5 targeting in Alzheimer's disease. | Kumar A et al. | β | 2015 | β |
| The role of 5-HT2A, 5-HT 2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice. | Carbonaro TM et al. | β | 2015 | β |
| The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease. | Rudy CC et al. | β | 2015 | β |
| Activation of group 2 metabotropic glutamate receptors reduces behavioral and electrographic correlates of pilocarpine induced status epilepticus. | Caulder EH et al. | β | 2014 | β |
| Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers. | Matias CM et al. | β | 2014 | β |
| Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder. | Kandaswamy R et al. | β | 2014 | β |
| A specific role for hippocampal mossy fiber's zinc in rapid storage of emotional memories. | Ceccom J et al. | β | 2014 | β |
| Association analysis of the GRM8 gene with schizophrenia in the Uygur Chinese population. | Zhang L et al. | β | 2014 | β |
| Differential distribution of phospholipase C beta isoforms and diaglycerol kinase-beta in rodents cerebella corroborates the division of unipolar brush cells into two major subtypes. | SekerkovΓ‘ G et al. | β | 2014 | β |
| Differential expression of mGluR2 in the developing cerebral cortex of the mouse. | Venkatadri PS et al. | β | 2014 | β |
| Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [<sup>11</sup> C]ABP688 PET imaging. | Mathews WB et al. | β | 2014 | β |
| Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism. | D'Antoni S et al. | β | 2014 | β |
| Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures. | Tomioka NH et al. | β | 2014 | β |
| Glutamatergic candidate genes in autism spectrum disorder: an overview. | Chiocchetti AG et al. | β | 2014 | β |
| Group III metabotropic glutamate receptors: pharmacology, physiology and therapeutic potential. | Mercier MS et al. | β | 2014 | β |
| Group III mGlu receptor agonist, ACPT-I, exerts potential neuroprotective effects in vitro and in vivo. | Domin H et al. | β | 2014 | β |
| Information processing and synaptic plasticity at hippocampal mossy fiber terminals. | Evstratova A et al. | β | 2014 | β |
| Localization of kainate receptors in inner and outer hair cell synapses. | Fujikawa T et al. | β | 2014 | β |
| Metabotropic glutamatergic receptors and their ligands in drug addiction. | Pomierny-ChamioΕo L et al. | β | 2014 | β |
| Modulation of short-term plasticity in the corticothalamic circuit by group III metabotropic glutamate receptors. | Kyuyoung CL et al. | β | 2014 | β |
| Neurogenetics of aggressive behavior: studies in rodents. | Takahashi A et al. | β | 2014 | β |
| Neurophysiologic and antipsychotic profiles of TASP0433864, a novel positive allosteric modulator of metabotropic glutamate 2 receptor. | Hiyoshi T et al. | β | 2014 | β |
| Neuroprotective and symptomatic effects of targeting group III mGlu receptors in neurodegenerative disease. | Williams CJ et al. | β | 2014 | β |
| Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. | Duman RS | β | 2014 | β |
| Prenatal cocaine exposure uncouples mGluR1 from Homer1 and Gq Proteins. | Bakshi K et al. | β | 2014 | β |
| Role of metabotropic glutamate receptors in the regulation of pancreatic functions. | Babic T et al. | β | 2014 | β |
| Supraspinal metabotropic glutamate receptor subtype 8: a switch to turn off pain. | Palazzo E et al. | β | 2014 | β |
| The metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats. | Pitsikas N et al. | β | 2014 | β |
| Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface. | Simon AC et al. | β | 2013 | β |
| Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants. | Dwyer JM et al. | β | 2013 | β |
| Activation of synaptic group II metabotropic glutamate receptors induces long-term depression at GABAergic synapses in CNS neurons. | Tang ZQ et al. | β | 2013 | β |
| Activation requirements for metabotropic glutamate receptors. | Viaene AN et al. | β | 2013 | β |
| Contribution of the mGluR7 receptor to antiparkinsonian-like effects in rats: a behavioral study with the selective agonist AMN082. | Konieczny J et al. | β | 2013 | β |
| Correlative analysis of immunoreactivity in confocal laser-scanning microscopy and scanning electron microscopy with focused ion beam milling. | Sonomura T et al. | β | 2013 | β |
| Early antidepressant efficacy modulation by glutamatergic gene variants in the STAR*D. | Fabbri C et al. | β | 2013 | β |
| Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat. | Palazzo E et al. | β | 2013 | β |
| Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. | Sun W et al. | β | 2013 | β |
| Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats. | Johnson PL et al. | β | 2013 | β |
| Improved spatial learning is associated with increased hippocampal but not prefrontal long-term potentiation in mGluR4 knockout mice. | Iscru E et al. | β | 2013 | β |
| Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats. | Yang S et al. | β | 2013 | β |
| Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence. | Li X et al. | β | 2013 | β |
| Metabotropic glutamate receptors and glutamate transporters shape transmission at the developing retinogeniculate synapse. | Hauser JL et al. | β | 2013 | β |
| mGlu3 receptor and astrocytes: partners in neuroprotection. | Durand D et al. | β | 2013 | β |
| mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure. | Dwyer JM et al. | β | 2013 | β |
| Network state-dependent inhibition of identified hippocampal CA3 axo-axonic cells in vivo. | Viney TJ et al. | β | 2013 | β |
| Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice. | Dobi A et al. | β | 2013 | β |
| Optical control of metabotropic glutamate receptors. | Levitz J et al. | β | 2013 | β |
| Positive allosteric modulation of mGlu7 receptors by AMN082 affects sleep and wakefulness in the rat. | Cavas M et al. | β | 2013 | β |
| Presynaptic mGlu7 receptors control GABA release in mouse hippocampus. | Summa M et al. | β | 2013 | β |
| Regulation of metabotropic glutamate receptor 7 (mGluR7) internalization and surface expression by Ser/Thr protein phosphatase 1. | Suh YH et al. | β | 2013 | β |
| Regulation of the brain-gut axis by group III metabotropic glutamate receptors. | Julio-Pieper M et al. | β | 2013 | β |
| Reversal of novelty-induced hyperlocomotion and hippocampal c-Fos expression in GluA1 knockout male mice by the mGluR2/3 agonist LY354740. | Procaccini C et al. | β | 2013 | β |
| Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning. | Mukherjee S et al. | β | 2013 | β |
| Role of presynaptic metabotropic glutamate receptors in the induction of long-term synaptic plasticity of vesicular release. | Upreti C et al. | β | 2013 | β |
| Selective silencing of individual dendritic branches by an mGlu2-activated potassium conductance in dentate gyrus granule cells. | Brunner J et al. | β | 2013 | β |
| The changes in mGluR2 and mGluR7 expression in rat medial vestibular nucleus and flocculus following unilateral labyrinthectomy. | Zhou W et al. | β | 2013 | β |
| The glutamatergic system as a target for neuropathic pain relief. | Osikowicz M et al. | β | 2013 | β |
| The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety. | Grivas V et al. | β | 2013 | β |
| Activation of adenosineβ receptors induces antidepressant-like, anti-impulsive effects on differential reinforcement of low-rate 72-s behavior in rats. | Marek GJ | β | 2012 | β |
| Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. | Vera G et al. | β | 2012 | β |
| Activity-dependent regulation of synaptic strength by PSD-95 in CA1 neurons. | Zhang P et al. | β | 2012 | β |
| Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children. | Hino H et al. | β | 2012 | β |
| Computational quest for understanding the role of astrocyte signaling in synaptic transmission and plasticity. | De PittΓ M et al. | β | 2012 | β |
| Dendritic Signaling in Inhibitory Interneurons: Local Tuning via Group I Metabotropic Glutamate Receptors. | CamirΓ© O et al. | β | 2012 | β |
| Depression of release by mGluR8 alters Ca2+ dependence of release machinery. | Erdmann E et al. | β | 2012 | β |
| DHEAS induces short-term potentiation via the activation of a metabotropic glutamate receptor in the rat hippocampus. | Xu Y et al. | β | 2012 | β |
| Discovery of 1,4-disubstituted 3-cyano-2-pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor. | Cid JM et al. | β | 2012 | β |
| Epileptiform activity in the CA1 region of the hippocampus becomes refractory to attenuation by cannabinoids in part because of endogenous Ξ³-aminobutyric acid type B receptor activity. | Messer RD et al. | β | 2012 | β |
| Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7. | Ullmer C et al. | β | 2012 | β |
| Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease. | Sgambato-Faure V et al. | β | 2012 | β |
| GPCR mediated regulation of synaptic transmission. | Betke KM et al. | β | 2012 | β |
| Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons. | Kintscher M et al. | β | 2012 | β |
| Identification of mRNA for endocannabinoid biosynthetic enzymes within hippocampal pyramidal cells and CA1 stratum radiatum interneuron subtypes using quantitative real-time polymerase chain reaction. | Merrill CB et al. | β | 2012 | β |
| Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. | Ayala R et al. | β | 2012 | β |
| Metabotropic glutamate receptors for new treatments in schizophrenia. | Herman EJ et al. | β | 2012 | β |
| mTOR activation is required for the antidepressant effects of mGluRβ/β blockade. | Dwyer JM et al. | β | 2012 | β |
| NeuroD2 regulates the development of hippocampal mossy fiber synapses. | Wilke SA et al. | β | 2012 | β |
| Plasticity of NMDA receptor-mediated excitatory postsynaptic currents at perforant path inputs to dendrite-targeting interneurons. | Harney SC et al. | β | 2012 | β |
| Psychopharmacological treatment of schizophrenia: what do we have, and what could we get? | Ellenbroek BA | β | 2012 | β |
| Putative depolarisation-induced retrograde signalling accelerates the repeated hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus via group I metabotropic glutamate receptors. | Nuritova F et al. | β | 2012 | β |
| Regulation of Neuronal Protein Trafficking and Translocation by SUMOylation. | Berndt A et al. | β | 2012 | β |
| Roles of glutamate signaling in preclinical and/or mechanistic models of depression. | Tokita K et al. | β | 2012 | β |
| Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. | ΕmiaΕowska M et al. | β | 2012 | β |
| Structure of metabotropic glutamate receptor C-terminal domains in contact with interacting proteins. | Enz R | β | 2012 | β |
| Synthesis, radiolabelling and in vitro and in vivo evaluation of a novel fluorinated ABP688 derivative for the PET imaging of metabotropic glutamate receptor subtype 5. | Sephton SM et al. | β | 2012 | β |
| The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling. | Bradley SR et al. | β | 2012 | β |
| Therapeutic potential of metabotropic glutamate receptor modulators. | HovelsΓΈ N et al. | β | 2012 | β |
| Translational Concepts of mGluR5 in Synaptic Diseases of the Brain. | Piers TM et al. | β | 2012 | β |
| Activation of group I mGlu receptors contributes to facilitation of NMDA receptor membrane current in spinal dorsal horn neurons after hind paw inflammation in rats. | Yang K et al. | β | 2011 | β |
| Activity-dependent regulation of synaptic vesicle exocytosis and presynaptic short-term plasticity. | Mochida S | β | 2011 | β |
| Allosteric modulation of metabotropic glutamate receptors. | Sheffler DJ et al. | β | 2011 | β |
| A novel form of low-frequency hippocampal mossy fiber plasticity induced by bimodal mGlu1 receptor signaling. | Frausto SF et al. | β | 2011 | β |
| Ca/Calmodulin and presynaptic short-term plasticity. | Mochida S | β | 2011 | β |
| Characterization of NPY Y2 receptor protein expression in the mouse brain. II. Coexistence with NPY, the Y1 receptor, and other neurotransmitter-related molecules. | StaniΔ D et al. | β | 2011 | β |
| Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. | LudΓ‘nyi A et al. | β | 2011 | β |
| Differential effect of the mGlu5 receptor positive allosteric modulator ADX-47273 on early and late hippocampal LTP. | Kroker KS et al. | β | 2011 | β |
| Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex. | Carli M et al. | β | 2011 | β |
| Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors. | Ster J et al. | β | 2011 | β |
| Glutamatergic neuroplasticity in cocaine addiction. | Uys JD et al. | β | 2011 | β |
| High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons. | Cosgrove KE et al. | β | 2011 | β |
| Huntington's disease and Group I metabotropic glutamate receptors. | Ribeiro FM et al. | β | 2011 | β |
| Induction and expression rules of synaptic plasticity in hippocampal interneurons. | Laezza F et al. | β | 2011 | β |
| In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5). | Wanger-Baumann CA et al. | β | 2011 | β |
| Methodology for rapid measures of glutamate release in rat brain slices using ceramic-based microelectrode arrays: basic characterization and drug pharmacology. | Quintero JE et al. | β | 2011 | β |
| mGluR7 genetics and alcohol: intersection yields clues for addiction. | Gyetvai B et al. | β | 2011 | β |
| mGluRs modulate strength and timing of excitatory transmission in hippocampal area CA3. | Cosgrove KE et al. | β | 2011 | β |
| Multiple forms of long-term synaptic plasticity at hippocampal mossy fiber synapses on interneurons. | GalvΓ‘n EJ et al. | β | 2011 | β |
| Non-additive potentiation of glutamate release by phorbol esters and metabotropic mGlu7 receptor in cerebrocortical nerve terminals. | MartΓn R et al. | β | 2011 | β |
| Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. | Ceolin L et al. | β | 2011 | β |
| SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b. | DΓΌtting E et al. | β | 2011 | β |
| Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons. | Brown JT et al. | β | 2011 | β |
| Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. | Li X et al. | β | 2010 | β |
| Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats. | Masuoka T et al. | β | 2010 | β |
| Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. | Coyle JT et al. | β | 2010 | β |
| Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses. | Takayasu Y et al. | β | 2010 | β |
| Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction. | Olive MF | β | 2010 | β |
| Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression. | O'Mahony CM et al. | β | 2010 | β |
| Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7. | Niswender CM et al. | β | 2010 | β |
| Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. | Safiulina VF et al. | β | 2010 | β |
| Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants. | Benned-Jensen T et al. | β | 2010 | β |
| Effects of agents targeting glutamatergic systems on marble-burying behavior. | Iijima M et al. | β | 2010 | β |
| Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation. | Inada H et al. | β | 2010 | β |
| Group II metabotropic glutamate receptor activation by agonist LY379268 treatment increases the expression of brain derived neurotrophic factor in the mouse brain. | Di Liberto V et al. | β | 2010 | β |
| Group I metabotropic glutamate receptors are involved in TEA-induced long-term potentiation at mossy fiber-CA3 synapses in the rat hippocampus. | Suzuki E et al. | β | 2010 | β |
| Hippocampal mossy fiber synaptic transmission and its modulation. | Kobayashi K | β | 2010 | β |
| Interaction between Ephrins and mGlu5 metabotropic glutamate receptors in the induction of long-term synaptic depression in the hippocampus. | Piccinin S et al. | β | 2010 | β |
| Interneuron subtype specific activation of mGluR1/5 during epileptiform activity in hippocampus. | Sanon NT et al. | β | 2010 | β |
| Mechanisms underlying synapse-specific clustering of GABA(A) receptors. | Thomson AM et al. | β | 2010 | β |
| Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition. | Marek GJ | β | 2010 | β |
| Metabotropic glutamate receptor 7: at the interface of cognition and emotion. | O'Connor RM et al. | β | 2010 | β |
| Metabotropic glutamate receptors: gatekeepers of homeostasis. | Kuzmiski JB et al. | β | 2010 | β |
| Metabotropic glutamate receptors: physiology, pharmacology, and disease. | Niswender CM et al. | β | 2010 | β |
| Metabotropic glutamate receptors: their therapeutic potential in anxiety. | Spooren W et al. | β | 2010 | β |
| Metabotropic glutamate receptor subtype 5 antagonism in learning and memory. | Simonyi A et al. | β | 2010 | β |
| Non-synaptic receptors and transporters involved in brain functions and targets of drug treatment. | Vizi ES et al. | β | 2010 | β |
| Persistent synapse loss induced by repetitive LTD in developing rat hippocampal neurons. | Shinoda Y et al. | β | 2010 | β |
| The effect of mGlu8 deficiency in animal models of psychiatric diseases. | Fendt M et al. | β | 2010 | β |
| The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals. | MartΓn R et al. | β | 2010 | β |
| The mossy fiber bouton: the "common" or the "unique" synapse? | Rollenhagen A et al. | β | 2010 | β |
| The pharmacology of anxiety. | Durant C et al. | β | 2010 | β |
| Activation of group III metabotropic glutamate receptor reduces intracellular calcium in beta-amyloid peptide [31-35]-treated cortical neurons. | Zhao L et al. | β | 2009 | β |
| Acute administration of cocaine reduces metabotropic glutamate receptor 8 protein expression in the rat striatum in vivo. | Zhang GC et al. | β | 2009 | β |
| Allosteric modulation of metabotropic glutamate receptor 5 affects phosphorylation, internalization, and desensitization of the micro-opioid receptor. | SchrΓΆder H et al. | β | 2009 | β |
| Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. | Chen AC et al. | β | 2009 | β |
| beta-Phorbol ester-induced enhancement of exocytosis in large mossy fiber boutons of mouse hippocampus. | Hikima T et al. | β | 2009 | β |
| Chronic CXCL10 alters neuronal properties in rat hippocampal culture. | Cho J et al. | β | 2009 | β |
| Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration. | Rives ML et al. | β | 2009 | β |
| Developmental changes in short-term facilitation are opposite at temporoammonic synapses compared to Schaffer collateral synapses onto CA1 pyramidal cells. | Speed HE et al. | β | 2009 | β |
| Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala. | Hong I et al. | β | 2009 | β |
| Group III metabotropic glutamate receptors (mGluRs) modulate transmission of gustatory inputs in the brain stem. | Hallock RM et al. | β | 2009 | β |
| Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. | Besheer J et al. | β | 2009 | β |
| Involvement of Group II mGluRs in mossy fiber LTD. | Wostrack M et al. | β | 2009 | β |
| Metabotropic glutamate receptor 1 activity generates persistent, N-methyl-D-aspartate receptor-dependent depression of hippocampal pyramidal cell excitability. | Clement JP et al. | β | 2009 | β |
| Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. | Li X et al. | β | 2009 | β |
| Partial compensation for N-type Ca(2+) channel loss by P/Q-type Ca(2+) channels underlines the differential release properties supported by these channels at cerebrocortical nerve terminals. | Ladera C et al. | β | 2009 | β |
| Up-regulation of GLT-1 severely impairs LTD at mossy fibre--CA3 synapses. | Omrani A et al. | β | 2009 | β |
| Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro. | Wang W et al. | β | 2008 | β |
| Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice. | Lyon L et al. | β | 2008 | β |
| Amyloid beta peptides and glutamatergic synaptic dysregulation. | Parameshwaran K et al. | β | 2008 | β |
| Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways. | Young RL et al. | β | 2008 | β |
| A plateau potential mediated by the activation of extrasynaptic NMDA receptors in rat hippocampal CA1 pyramidal neurons. | Suzuki T et al. | β | 2008 | β |
| Band 4.1 proteins are expressed in the retina and interact with both isoforms of the metabotropic glutamate receptor type 8. | Rose M et al. | β | 2008 | β |
| Blockade of glutamate transporters leads to potentiation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex via group II metabotropic glutamate receptor activation. | Oliveira JF et al. | β | 2008 | β |
| Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex. | Boer K et al. | β | 2008 | β |
| Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7. | Suh YH et al. | β | 2008 | β |
| Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice. | Goddyn H et al. | β | 2008 | β |
| Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: a comparative real-time PCR analysis. | Ermolinsky B et al. | β | 2008 | β |
| Differential mechanisms of transmission and plasticity at mossy fiber synapses. | McBain CJ | β | 2008 | β |
| Distribution of metabotropic glutamate 2 and 3 receptors in the rat forebrain: Implication in emotional responses and central disinhibition. | Gu G et al. | β | 2008 | β |
| Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy. | Pacheco Otalora LF et al. | β | 2008 | β |
| Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated. | Ayala JE et al. | β | 2008 | β |
| Impaired expression and function of group II metabotropic glutamate receptors in pilocarpine-treated chronically epileptic rats. | Garrido-Sanabria ER et al. | β | 2008 | β |
| Implication of neuronal Ca2+ -sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia. | Gierke P et al. | β | 2008 | β |
| Increases in intracellular calcium triggered by channelrhodopsin-2 potentiate the response of metabotropic glutamate receptor mGluR7. | Caldwell JH et al. | β | 2008 | β |
| Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus. | Chiu CQ et al. | β | 2008 | β |
| Metabotropic glutamate 1 receptor: current concepts and perspectives. | Ferraguti F et al. | β | 2008 | β |
| mGlu1alpha receptors are co-expressed with CB1 receptors in a subset of interneurons in the CA1 region of organotypic hippocampal slice cultures and adult rat brain. | Boscia F et al. | β | 2008 | β |
| Modulation of excitation by metabotropic glutamate receptors. | KnΓΆpfel T et al. | β | 2008 | β |
| Mood disorders: regulation by metabotropic glutamate receptors. | Pilc A et al. | β | 2008 | β |
| Presynaptic glutamate receptors: physiological functions and mechanisms of action. | Pinheiro PS et al. | β | 2008 | β |
| Presynaptic metabotropic glutamate and GABAB receptors. | Raiteri M | β | 2008 | β |
| Role of glutamate autoreceptors at hippocampal mossy fiber synapses. | Kwon HB et al. | β | 2008 | β |
| Satellite NG2 progenitor cells share common glutamatergic inputs with associated interneurons in the mouse dentate gyrus. | Mangin JM et al. | β | 2008 | β |
| Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus. | Le Vasseur M et al. | β | 2008 | β |
| Spontaneous release from mossy fiber terminals inhibits Ni2+-sensitive T-type Ca2+ channels of CA3 pyramidal neurons in the rat organotypic hippocampal slice. | Reid CA et al. | β | 2008 | β |
| State-dependent cAMP sensitivity of presynaptic function underlies metaplasticity in a hippocampal feedforward inhibitory circuit. | Pelkey KA et al. | β | 2008 | β |
| Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation. | Kim J et al. | β | 2008 | β |
| Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patients. | Puls I et al. | β | 2008 | β |
| Target-cell-dependent plasticity within the mossy fibre-CA3 circuit reveals compartmentalized regulation of presynaptic function at divergent release sites. | Pelkey KA et al. | β | 2008 | β |
| Target-cell specificity of kainate autoreceptor and Ca2+-store-dependent short-term plasticity at hippocampal mossy fiber synapses. | Scott R et al. | β | 2008 | β |
| The association analysis of RELN and GRM8 genes with autistic spectrum disorder in Chinese Han population. | Li H et al. | β | 2008 | β |
| The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. | Li X et al. | β | 2008 | β |
| The possible involvement of metabotropic glutamate receptors in schizophrenia. | Krivoy A et al. | β | 2008 | β |
| Tonic activation of group I mGluRs modulates inhibitory synaptic strength by regulating KCC2 activity. | Banke TG et al. | β | 2008 | β |
| Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. | Rangaswamy M et al. | β | 2008 | β |
| Upregulation of metabotropic glutamate receptor 8 mRNA expression in the rat forebrain after repeated amphetamine administration. | Parelkar NK et al. | β | 2008 | β |
| Activator protein-1 responsive to the group II metabotropic glutamate receptor subtype in association with intracellular calcium in cultured rat cortical neurons. | Sugiyama C et al. | β | 2007 | β |
| An influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats. | Ossowska K et al. | β | 2007 | β |
| Anticonvulsive effect of a selective mGluR8 agonist (S)-3,4-dicarboxyphenylglycine (S-3,4-DCPG) in the mouse pilocarpine model of status epilepticus. | Jiang FL et al. | β | 2007 | β |
| Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent. | Stachowicz K et al. | β | 2007 | β |
| Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent. | Stachowicz K et al. | β | 2007 | β |
| Beta/gamma oscillatory activity in the CA3 hippocampal area is depressed by aberrant GABAergic transmission from the dentate gyrus after seizures. | TreviΓ±o M et al. | β | 2007 | β |
| Cellular localization of mGluR3 and mGluR5 mRNAs in normal and injured rat brain. | Mudo G et al. | β | 2007 | β |
| Chronic interleukin-6 alters the level of synaptic proteins in hippocampus in culture and in vivo. | Vereyken EJ et al. | β | 2007 | β |
| Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex. | WieroΕska JM et al. | β | 2007 | β |
| Constitutive endocytosis of the metabotropic glutamate receptor mGluR7 is clathrin-independent. | Lavezzari G et al. | β | 2007 | β |
| Developmental dependence, the role of the kinases p38 MAPK and PKC, and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus. | Wang Q et al. | β | 2007 | β |
| Differential expression of cerebellar metabotropic glutamate receptors mGLUR2/3 and mGLUR4a after the administration of a convulsant drug and the adenosine analogue cyclopentyladenosine. | Girardi ES et al. | β | 2007 | β |
| Differential expression of posttetanic potentiation and retrograde signaling mediate target-dependent short-term synaptic plasticity. | Beierlein M et al. | β | 2007 | β |
| Differential regulation at functionally divergent release sites along a common axon. | Pelkey KA et al. | β | 2007 | β |
| Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia. | Robbins MJ et al. | β | 2007 | β |
| Expression of group II metabotropic glutamate receptors in rat gustatory papillae. | Toyono T et al. | β | 2007 | β |
| Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation. | Zhang C et al. | β | 2007 | β |
| Group II metabotropic glutamate receptors in anxiety circuitry: correspondence of physiological response and subcellular distribution. | Muly EC et al. | β | 2007 | β |
| Group I metabotropic glutamate receptor-dependent TRPC channel trafficking in hippocampal neurons. | Wang M et al. | β | 2007 | β |
| Group S8A serine proteases, including a novel enzyme cadeprin, induce long-lasting, metabotropic glutamate receptor-dependent synaptic depression in rat hippocampal slices. | MacGregor DG et al. | β | 2007 | β |
| High-resolution quantitative visualization of glutamate and GABA receptors at central synapses. | Masugi-Tokita M et al. | β | 2007 | β |
| Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors. | Kammermeier PJ et al. | β | 2007 | β |
| Involvement of hippocampal metabotropic glutamate receptors in radial maze performance. | Hayashi K et al. | β | 2007 | β |
| Loss of metabotropic glutamate receptor-dependent long-term depression via downregulation of mGluR5 after status epilepticus. | Kirschstein T et al. | β | 2007 | β |
| Metabotropic glutamate receptor 4-immunopositive terminals of medium-sized spiny neurons selectively form synapses with cholinergic interneurons in the rat neostriatum. | Kuramoto E et al. | β | 2007 | β |
| Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. | Palucha A et al. | β | 2007 | β |
| mGluR7 inhibits glutamate release through a PKC-independent decrease in the activity of P/Q-type Ca2+ channels and by diminishing cAMP in hippocampal nerve terminals. | MartΓn R et al. | β | 2007 | β |
| Modulation of a spinal locomotor network by metabotropic glutamate receptors. | Chapman RJ et al. | β | 2007 | β |
| Molecular anatomy of the postsynaptic density. | Okabe S | β | 2007 | β |
| Mossy fiber synaptic transmission: communication from the dentate gyrus to area CA3. | Jaffe DB et al. | β | 2007 | β |
| Neuromodulation by glutamate and acetylcholine can change circuit dynamics by regulating the relative influence of afferent input and excitatory feedback. | Giocomo LM et al. | β | 2007 | β |
| Neurotransmitters and the development of neuronal circuits. | Ruediger T et al. | β | 2007 | β |
| Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception. | Marabese I et al. | β | 2007 | β |
| Reduction of metabotropic glutamate receptor-mediated heterosynaptic inhibition of developing MNTB-LSO inhibitory synapses. | Nishimaki T et al. | β | 2007 | β |
| Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex. | Renoldi G et al. | β | 2007 | β |
| The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat. | Maione S et al. | β | 2007 | β |
| The coexistence of multiple receptors in a single nerve terminal provides evidence for pre-synaptic integration. | Ladera C et al. | β | 2007 | β |
| The effect of intrahippocampal injection of group II and III metobotropic glutamate receptor agonists on anxiety; the role of neuropeptide Y. | SmiaΕowska M et al. | β | 2007 | β |
| The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task. | Semenova S et al. | β | 2007 | β |
| The preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268. | Imre G | β | 2007 | β |
| The role of group I metabotropic glutamate receptors in schizophrenia. | Pietraszek M et al. | β | 2007 | β |
| Abnormal mGluR2/3 expression in the perforant path termination zones and mossy fibers of chronically epileptic rats. | Pacheco Otalora LF et al. | β | 2006 | β |
| Antidepressant-like and anxiolytic-like actions of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of male Wistar rats. | Molina-HernΓ‘ndez M et al. | β | 2006 | β |
| BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. | Mizoguchi Y et al. | β | 2006 | β |
| Ca2+-dependent mechanisms of presynaptic control at central synapses. | Rusakov DA | β | 2006 | β |
| Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticity. | Pelkey KA et al. | β | 2006 | β |
| Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. | Kulik A et al. | β | 2006 | β |
| Difference in time course of modulation of synaptic transmission by group II versus group III metabotropic glutamate receptors in region CA1 of the hippocampus. | Giocomo LM et al. | β | 2006 | β |
| Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain. | Li W et al. | β | 2006 | β |
| Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression. | Volk LJ et al. | β | 2006 | β |
| Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus. | Linden AM et al. | β | 2006 | β |
| Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity. | Schmid S et al. | β | 2006 | β |
| Electrophysiological effects of three groups of glutamate metabotropic receptors in rat piriform cortex. | Tan Y et al. | β | 2006 | β |
| Endocannabinoid-mediated synaptic plasticity in the CNS. | Chevaleyre V et al. | β | 2006 | β |
| GABA(B) receptors in the centromedian/parafascicular thalamic nuclear complex: an ultrastructural analysis of GABA(B)R1 and GABA(B)R2 in the monkey thalamus. | Villalba RM et al. | β | 2006 | β |
| Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus. | Naie K et al. | β | 2006 | β |
| Ion dependence of ligand binding to metabotropic glutamate receptors. | Kuang D et al. | β | 2006 | β |
| Is the functional interaction between adenosine A(2A) receptors and metabotropic glutamate 5 receptors a general mechanism in the brain? Differences and similarities between the striatum and the hippocampus. | Tebano MT et al. | β | 2006 | β |
| Metabotropic glutamate receptors. | Ferraguti F et al. | β | 2006 | β |
| Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy. | Alexander GM et al. | β | 2006 | β |
| mGluR2 acts through inhibitory Galpha subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses. | Nicholls RE et al. | β | 2006 | β |
| Opposite regulation of Slick and Slack K+ channels by neuromodulators. | Santi CM et al. | β | 2006 | β |
| Properties of long-term synaptic plasticity and metaplasticity in organotypic slice cultures of rat hippocampus. | Mellentin C et al. | β | 2006 | β |
| Spike-timing-dependent plasticity at resting and conditioned lateral perforant path synapses on granule cells in the dentate gyrus: different roles of N-methyl-D-aspartate and group I metabotropic glutamate receptors. | Lin YW et al. | β | 2006 | β |
| Subchronic administration of LY354740 does not modify ketamine-evoked behavior and neuronal activity in rats. | Imre G et al. | β | 2006 | β |
| Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: involvement of a metabotropic glutamate receptor. | LasztΓ³czi B et al. | β | 2006 | β |
| The characteristics of LTP induced in hippocampal slices are dependent on slice-recovery conditions. | Capron B et al. | β | 2006 | β |
| Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity. | Alexander GM et al. | β | 2006 | β |
| Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects. | Tebano MT et al. | β | 2005 | β |
| Altered glutamate and GABA release within thalamocortical circuitry in metabotropic glutamate receptor 4 knockout mice. | Wang X et al. | β | 2005 | β |
| Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice. | Linden AM et al. | β | 2005 | β |
| Anxiolytic-like effects of mGlu1 and mGlu5 receptor antagonists in rats. | Pietraszek M et al. | β | 2005 | β |
| Comparison of c-Fos induction in the brain by the mGlu2/3 receptor antagonist LY341495 and agonist LY354740: evidence for widespread endogenous tone at brain mGlu2/3 receptors in vivo. | Linden AM et al. | β | 2005 | β |
| Coupling of metabotropic glutamate receptor 8 to N-type Ca2+ channels in rat sympathetic neurons. | Guo J et al. | β | 2005 | β |
| Differential distribution of release-related proteins in the hippocampal CA3 area as revealed by freeze-fracture replica labeling. | Hagiwara A et al. | β | 2005 | β |
| Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. | Marabese I et al. | β | 2005 | β |
| Diffusional extrasynaptic neurotransmission via glutamate and GABA. | Sem'yanov AV | β | 2005 | β |
| Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPgammas binding. | Richards G et al. | β | 2005 | β |
| Down-regulation of metabotropic glutamate receptor 1alpha in globus pallidus and substantia nigra of parkinsonian monkeys. | Kaneda K et al. | β | 2005 | β |
| Effects of the mGluR2/3 agonist LY354740 on computerized tasks of attention and working memory in marmoset monkeys. | Spinelli S et al. | β | 2005 | β |
| Expression of groups I and II metabotropic glutamate receptors in the rat brain during aging. | Simonyi A et al. | β | 2005 | β |
| Expression patterns of Group III metabotropic glutamate receptors mGluR4 and mGluR8 in multiple sclerosis lesions. | Geurts JJ et al. | β | 2005 | β |
| GABA release modified by adenosine receptors in mouse hippocampal slices under normal and ischemic conditions. | Saransaari P et al. | β | 2005 | β |
| Global ischemia downregulates the function of metabotropic glutamate receptor subtype 5 in hippocampal CA1 pyramidal neurons. | Yeh TH et al. | β | 2005 | β |
| Glutamate and GABA receptor signalling in the developing brain. | LujΓ‘n R et al. | β | 2005 | β |
| Group II and III metabotropic glutamate receptors suppress excitatory synaptic transmission in the dorsolateral bed nucleus of the stria terminalis. | Grueter BA et al. | β | 2005 | β |
| Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare. | Price CJ et al. | β | 2005 | β |
| Group I mGluR-induced epileptogenesis: distinct and overlapping roles of mGluR1 and mGluR5 and implications for antiepileptic drug design. | Wong RK et al. | β | 2005 | β |
| Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function. | Ciruela F et al. | β | 2005 | β |
| Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8. | Duvoisin RM et al. | β | 2005 | β |
| Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats. | Naie K et al. | β | 2005 | β |
| Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory. | HΓΆlscher C et al. | β | 2005 | β |
| Mechanisms of late-onset cognitive decline after early-life stress. | Brunson KL et al. | β | 2005 | β |
| Metabotropic glutamate receptor 8-expressing nerve terminals target subsets of GABAergic neurons in the hippocampus. | Ferraguti F et al. | β | 2005 | β |
| mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition. | Pietraszek M et al. | β | 2005 | β |
| mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition. | Pelkey KA et al. | β | 2005 | β |
| Modulatory effects mediated by metabotropic glutamate receptor 5 on lateral geniculate nucleus relay cells. | de Labra C et al. | β | 2005 | β |
| New type of synaptically mediated epileptiform activity independent of known glutamate and GABA receptors. | Skov J et al. | β | 2005 | β |
| Opposite effects of Zn on the in vitro binding of [3H]LY354740 to recombinant and native metabotropic glutamate 2 and 3 receptors. | Malherbe P et al. | β | 2005 | β |
| Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat. | de Novellis V et al. | β | 2005 | β |
| Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanisms. | Naie K et al. | β | 2005 | β |
| Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGLU(2/3) receptor agonist LY379268. | Greco B et al. | β | 2005 | β |
| Pias1 interaction and sumoylation of metabotropic glutamate receptor 8. | Tang Z et al. | β | 2005 | β |
| Presynaptic homeostatic plasticity rescues long-term depression after chronic Delta 9-tetrahydrocannabinol exposure. | Mato S et al. | β | 2005 | β |
| Spontaneous release of neuropeptide Y tonically inhibits recurrent mossy fiber synaptic transmission in epileptic brain. | Tu B et al. | β | 2005 | β |
| Sprouting of mossy fibers and presynaptic inhibition by group II metabotropic glutamate receptors in pilocarpine-treated rat hippocampal slice cultures. | Thomas AM et al. | β | 2005 | β |
| Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons. | Harms KJ et al. | β | 2005 | β |
| Synaptic plasticity at hippocampal mossy fibre synapses. | Nicoll RA et al. | β | 2005 | β |
| Target-cell-specific left-right asymmetry of NMDA receptor content in schaffer collateral synapses in epsilon1/NR2A knock-out mice. | Wu Y et al. | β | 2005 | β |
| The GABAergic projection of the dentate gyrus to hippocampal area CA3 of the rat: pre- and postsynaptic actions after seizures. | TreviΓ±o M et al. | β | 2005 | β |
| The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats. | PΓΆschel B et al. | β | 2005 | β |
| The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors. | Bortolotto ZA et al. | β | 2005 | β |
| The role of group I metabotropic glutamate receptors in neuronal excitotoxicity in Alzheimer's disease. | Tsai VW et al. | β | 2005 | β |
| Tuning the network: modulation of neuronal microcircuits in the spinal cord and hippocampus. | LeBeau FE et al. | β | 2005 | β |
| Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. | Lee HG et al. | β | 2004 | β |
| Activation of group I metabotropic glutamate receptors enhances efficacy of glutamatergic inputs to neonatal rat hypoglossal motoneurons in vitro. | Sharifullina E et al. | β | 2004 | β |
| Age-related changes in the expression of axonal and glial group I metabotropic glutamate receptor in the rat substantia nigra pars reticulata. | Hubert GW et al. | β | 2004 | β |
| An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro. | Wu J et al. | β | 2004 | β |
| A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. | Yang L et al. | β | 2004 | β |
| Anxiolytic activity of the MGLU2/3 receptor agonist LY354740 on the elevated plus maze is associated with the suppression of stress-induced c-Fos in the hippocampus and increases in c-Fos induction in several other stress-sensitive brain regions. | Linden AM et al. | β | 2004 | β |
| Astrocyte activation of presynaptic metabotropic glutamate receptors modulates hippocampal inhibitory synaptic transmission. | Liu QS et al. | β | 2004 | β |
| Calcium dependence of native metabotropic glutamate receptor signaling in central neurons. | Tabata T et al. | β | 2004 | β |
| Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus. | Simonyi A et al. | β | 2004 | β |
| Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat. | Kogo N et al. | β | 2004 | β |
| Discrete synaptic states define a major mechanism of synapse plasticity. | Montgomery JM et al. | β | 2004 | β |
| Distinct properties of presynaptic group II and III metabotropic glutamate receptor-mediated inhibition of perforant pathway-CA1 EPSCs. | Capogna M | β | 2004 | β |
| Frequency dependence of synaptic vesicle exocytosis in aortic baroreceptor neurons and the role of group III mGluRs. | Pamidimukkala J et al. | β | 2004 | β |
| GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. | Somogyi J et al. | β | 2004 | β |
| GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism. | Sanabria ER et al. | β | 2004 | β |
| Group III metabotropic glutamate receptors maintain tonic inhibition of excitatory synaptic input to hypocretin/orexin neurons. | Acuna-Goycolea C et al. | β | 2004 | β |
| Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats. | PaΕucha A et al. | β | 2004 | β |
| Group I metabotropic glutamate receptors regulate the frequency-response function of hippocampal CA1 synapses for the induction of LTP and LTD. | van Dam EJ et al. | β | 2004 | β |
| Heterogeneity and specificity of presynaptic Ca2+ current modulation by mGluRs at individual hippocampal synapses. | Rusakov DA et al. | β | 2004 | β |
| Hippocampal mossy fiber calcium transients are maintained during long-term potentiation and are inhibited by endogenous zinc. | Quinta-Ferreira ME et al. | β | 2004 | β |
| Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. | Notomi T et al. | β | 2004 | β |
| Immunolocalization of metabotropic glutamate receptor 1alpha (mGluR1alpha) in distinct classes of interneuron in the CA1 region of the rat hippocampus. | Ferraguti F et al. | β | 2004 | β |
| L-CCG-I activates group III metabotropic glutamate receptors in the hippocampal CA3 region. | Kirschstein T et al. | β | 2004 | β |
| Medial perforant path inhibition mediated by mGluR7 is reduced after status epilepticus. | Bough KJ et al. | β | 2004 | β |
| Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: a quantitative autoradiographic study using [3H]R214127. | Lavreysen H et al. | β | 2004 | β |
| Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus. | Tang FR et al. | β | 2004 | β |
| Metabotropic glutamate receptors modulate ischemia-induced GABA release in mouse hippocampal slices. | Saransaari P et al. | β | 2004 | β |
| Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system. | Simeone TA et al. | β | 2004 | β |
| Partial involvement of group I metabotropic glutamate receptors in the neurotoxicity of 3-N-oxalyl-L-2,3-diaminopropanoic acid (L-beta-ODAP). | Kusama-Eguchi K et al. | β | 2004 | β |
| Perisomatic glutamatergic axon terminals: a novel feature of cortical synaptology revealed by vesicular glutamate transporter 1 immunostaining. | Alonso-Nanclares L et al. | β | 2004 | β |
| Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent. | Higgins GA et al. | β | 2004 | β |
| Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia. | Takaki H et al. | β | 2004 | β |
| Prenatal ethanol exposure reduces mGluR5 receptor number and function in the dentate gyrus of adult offspring. | Galindo R et al. | β | 2004 | β |
| Proteomic analysis of native metabotropic glutamate receptor 5 protein complexes reveals novel molecular constituents. | Farr CD et al. | β | 2004 | β |
| Quantal transmission at mossy fibre targets in the CA3 region of the rat hippocampus. | Lawrence JJ et al. | β | 2004 | β |
| Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats. | Klausnitzer J et al. | β | 2004 | β |
| Synapse-specific mGluR1-dependent long-term potentiation in interneurones regulates mouse hippocampal inhibition. | Lapointe V et al. | β | 2004 | β |
| Synaptically stimulated induction of group I metabotropic glutamate receptor-dependent long-term depression and depotentiation is inhibited by prior activation of metabotropic glutamate receptors and protein kinase C. | Wu J et al. | β | 2004 | β |
| The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety. | Busse CS et al. | β | 2004 | β |
| The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology. | Bogdanik L et al. | β | 2004 | β |
| The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region. | Francesconi W et al. | β | 2004 | β |
| The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats. | Campbell UC et al. | β | 2004 | β |
| [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. | Lavreysen H et al. | β | 2003 | β |
| Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. | Lee JJ et al. | β | 2003 | β |
| Activation of metabotropic glutamate 5 and NMDA receptors underlies the induction of persistent bursting and associated long-lasting changes in CA3 recurrent connections. | Stoop R et al. | β | 2003 | β |
| Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity. | Taylor DL et al. | β | 2003 | β |
| An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path-dentate gyrus synapse in freely moving rats. | Manahan-Vaughan D et al. | β | 2003 | β |
| Anticonvulsant dicarboxyphenylglycines differentially modulate excitatory amino acid release in the rat cerebral cortex. | Lee JJ et al. | β | 2003 | β |
| Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. | Cryan JF et al. | β | 2003 | β |
| Associative mossy fibre LTP induced by pairing presynaptic stimulation with postsynaptic hyperpolarization of CA3 neurons in rat hippocampal slice. | Sokolov MV et al. | β | 2003 | β |
| Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry. | Kawakami R et al. | β | 2003 | β |
| Characteristics of GABA release modified by glutamate receptors in mouse hippocampal slices. | Saransaari P et al. | β | 2003 | β |
| Co-expression of metabotropic glutamate receptor 7 and N-type Ca(2+) channels in single cerebrocortical nerve terminals of adult rats. | MillΓ‘n C et al. | β | 2003 | β |
| Different binding motifs in metabotropic glutamate receptor type 7b for filamin A, protein phosphatase 1C, protein interacting with protein kinase C (PICK) 1 and syntenin allow the formation of multimeric protein complexes. | Enz R et al. | β | 2003 | β |
| Direct interaction and functional coupling between metabotropic glutamate receptor subtype 1 and voltage-sensitive Cav2.1 Ca2+ channel. | Kitano J et al. | β | 2003 | β |
| Down-regulation of mGluR8 in pilocarpine epileptic rats. | Kral T et al. | β | 2003 | β |
| Effects of a selective metabotropic glutamate receptor agonist on the micturition reflex pathway in urethane-anesthetized rats. | Tanaka H et al. | β | 2003 | β |
| Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. | Aronica E et al. | β | 2003 | β |
| GABA and GABAA receptors at hippocampal mossy fibre synapses. | Bergersen L et al. | β | 2003 | β |
| Glutamate metabotropic receptors as targets for drug therapy in epilepsy. | Moldrich RX et al. | β | 2003 | β |
| Group II and III metabotropic glutamate receptors and the control of the nucleus reticularis thalami input to rat thalamocortical neurones in vitro. | Turner JP et al. | β | 2003 | β |
| Group III metabotropic glutamate receptors as autoreceptors in the cerebellar cortex. | Lorez M et al. | β | 2003 | β |
| Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex. | Zhai Y et al. | β | 2003 | β |
| Group I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequences. | Croci C et al. | β | 2003 | β |
| Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability. | Chevaleyre V et al. | β | 2003 | β |
| High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus. | Somogyi P et al. | β | 2003 | β |
| Increased c-Fos expression in the centromedial nucleus of the thalamus in metabotropic glutamate 8 receptor knockout mice following the elevated plus maze test. | Linden AM et al. | β | 2003 | β |
| Increased tonic activation of presynaptic metabotropic glutamate receptors in the rat supraoptic nucleus following chronic dehydration. | Boudaba C et al. | β | 2003 | β |
| Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens. | Xi ZX et al. | β | 2003 | β |
| Interactions between adenosine and metabotropic glutamate receptors in the rat hippocampal slice. | Shahraki A et al. | β | 2003 | β |
| Interneuron diversity series: containing the detonation--feedforward inhibition in the CA3 hippocampus. | Lawrence JJ et al. | β | 2003 | β |
| Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro. | Gisabella B et al. | β | 2003 | β |
| Metabotropic glutamate type 1alpha receptor localizes in low-density caveolin-rich plasma membrane fractions. | BurgueΓ±o J et al. | β | 2003 | β |
| mGluR2 postsynaptically senses granule cell inputs at Golgi cell synapses. | Watanabe D et al. | β | 2003 | β |
| Modulation of epileptiform burst frequency by the metabotropic glutamate receptor subtype mGluR3. | Lea PM et al. | β | 2003 | β |
| Mossy fibre synaptic NMDA receptors trigger non-Hebbian long-term potentiation at entorhino-CA3 synapses in the rat. | Tsukamoto M et al. | β | 2003 | β |
| Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound. | Ito Y et al. | β | 2003 | β |
| Protective effect of LY379268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex. | Okamura N et al. | β | 2003 | β |
| Reduction of excitatory postsynaptic responses by persistently active metabotropic glutamate receptors in the hippocampus. | Losonczy A et al. | β | 2003 | β |
| Regulation of vesicle traffic and neurotransmitter release in isolated nerve terminals. | Ghijsen WE et al. | β | 2003 | β |
| Selective modulation of excitatory and inhibitory microcircuits by dopamine. | Gao WJ et al. | β | 2003 | β |
| Short-term frequency-dependent plasticity at recurrent mossy fiber synapses of the epileptic brain. | Feng L et al. | β | 2003 | β |
| Silent synapses: what are they telling us about long-term potentiation? | Kullmann DM | β | 2003 | β |
| Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. | Kulik A et al. | β | 2003 | β |
| Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells. | Higashida H et al. | β | 2003 | β |
| The GABAergic phenotype of the "glutamatergic" granule cells of the dentate gyrus. | GutiΓ©rrez R | β | 2003 | β |
| The mechanism of presynaptic long-term depression mediated by group I metabotropic glutamate receptors. | Tan Y et al. | β | 2003 | β |
| The neurobiology and control of anxious states. | Millan MJ | β | 2003 | β |
| The recurrent mossy fiber pathway of the epileptic brain. | Nadler JV | β | 2003 | β |
| Toluene-induced locomotor activity is blocked by 6-hydroxydopamine lesions of the nucleus accumbens and the mGluR2/3 agonist LY379268. | Riegel AC et al. | β | 2003 | β |
| Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. | Fukami S et al. | β | 2002 | β |
| Activation of group I mGluRs elicits different responses in murine CA1 and CA3 pyramidal cells. | Chuang SC et al. | β | 2002 | β |
| Activation of metabotropic glutamate receptors by repetitive stimulation in auditory cortex. | Bandrowski AE et al. | β | 2002 | β |
| Activity-dependent expression of simultaneous glutamatergic and GABAergic neurotransmission from the mossy fibers in vitro. | GutiΓ©rrez R | β | 2002 | β |
| Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activation. | Ohno-Shosaku T et al. | β | 2002 | β |
| Developmental regulation of metabotropic glutamate receptor 5b protein in rodent brain. | Romano C et al. | β | 2002 | β |
| Differential regulation of synaptic transmission by mGlu2 and mGlu3 at the perforant path inputs to the dentate gyrus and CA1 revealed in mGlu2 -/- mice. | Kew JN et al. | β | 2002 | β |
| Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei. | Grassi S et al. | β | 2002 | β |
| Dissociation of protein kinase-mediated regulation of metabotropic glutamate receptor 7 (mGluR7) interactions with calmodulin and regulation of mGluR7 function. | Sorensen SD et al. | β | 2002 | β |
| Distinct physiological roles of the Gq-coupled metabotropic glutamate receptors Co-expressed in the same neuronal populations. | Valenti O et al. | β | 2002 | β |
| Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS. | Corti C et al. | β | 2002 | β |
| Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus. | SmiaΕowska M et al. | β | 2002 | β |
| Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex. | Renger JJ et al. | β | 2002 | β |
| Expression of metabotropic glutamate receptor 8 in autonomic cell groups of the medulla oblongata of the rat. | Pamidimukkala J et al. | β | 2002 | β |
| Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae. | Toyono T et al. | β | 2002 | β |
| Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses. | Tabata T et al. | β | 2002 | β |
| Functional genomics in experimental and human temporal lobe epilepsy: powerful new tools to identify molecular disease mechanisms of hippocampal damage. | Becker AJ et al. | β | 2002 | β |
| Glutamatergic modulation of GABAergic signaling among hippocampal interneurons: novel mechanisms regulating hippocampal excitability. | Kullmann DM et al. | β | 2002 | β |
| Glutamate transporters alterations in the reorganizing dentate gyrus are associated with progressive seizure activity in chronic epileptic rats. | Gorter JA et al. | β | 2002 | β |
| G-protein-coupled receptors for neurotransmitter amino acids: C-terminal tails, crowded signalosomes. | El Far O et al. | β | 2002 | β |
| Group I and II metabotropic glutamate receptors modulate respiratory activity in the lamprey. | Bongianni F et al. | β | 2002 | β |
| Group III mGlu receptor agonists potentiate the anticonvulsant effect of AMPA and NMDA receptor block. | De Sarro G et al. | β | 2002 | β |
| Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat. | Koyama R et al. | β | 2002 | β |
| Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro. | Rush AM et al. | β | 2002 | β |
| Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1. | Miura M et al. | β | 2002 | β |
| Group I metabotropic glutamate receptors (mGluRs) modulate visual responses in the superficial superior colliculus of the rat. | Cirone J et al. | β | 2002 | β |
| Group I mGluRs increase excitability of hippocampal CA1 pyramidal neurons by a PLC-independent mechanism. | Ireland DR et al. | β | 2002 | β |
| Increased anxiety-related behavior in mice deficient for metabotropic glutamate 8 (mGlu8) receptor. | Linden AM et al. | β | 2002 | β |
| Interaction between vanilloid and glutamate receptors in the central modulation of nociception. | Palazzo E et al. | β | 2002 | β |
| Localization and function of group III metabotropic glutamate receptors in rat pancreatic islets. | Tong Q et al. | β | 2002 | β |
| Long-term effects of prenatal stress on dopamine and glutamate receptors in adult rat brain. | Berger MA et al. | β | 2002 | β |
| Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity? | Cozzi A et al. | β | 2002 | β |
| Metabotropic Glutamate Receptors and Epileptogenesis. | Wong RK et al. | β | 2002 | β |
| Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats. | Kulla A et al. | β | 2002 | β |
| Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors. | Zhai J et al. | β | 2002 | β |
| Modulation of stress-induced and stimulated hyperprolactinemia with the group II metabotropic glutamate receptor selective agonist, LY379268. | Johnson MP et al. | β | 2002 | β |
| Molecular determinants of high affinity binding to group III metabotropic glutamate receptors. | Rosemond E et al. | β | 2002 | β |
| Neurochemical characterization of receptor-expressing cell populations by in vivo agonist-induced internalization: insights from the somatostatin sst2A receptor. | Csaba Z et al. | β | 2002 | β |
| Neuroprotective activity of metabotropic glutamate receptor ligands. | Flor PJ et al. | β | 2002 | β |
| Performance deficits of mGluR8 knockout mice in learning tasks: the effects of null mutation and the background genotype. | Gerlai R et al. | β | 2002 | β |
| Permissive effect of voltage on mGlu 7 receptor subtype signaling in neurons. | Perroy J et al. | β | 2002 | β |
| PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7. | Perroy J et al. | β | 2002 | β |
| Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites. | LΓΆrincz A et al. | β | 2002 | β |
| Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. | Watabe AM et al. | β | 2002 | β |
| Presynaptic group III mGluR modulation of short-term plasticity in the lateral perforant path of the dentate gyrus in vitro. | Rush AM et al. | β | 2002 | β |
| Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus. | Dietrich D et al. | β | 2002 | β |
| Role of group II and group III metabotropic glutamate receptors in spinal cord injury. | Mills CD et al. | β | 2002 | β |
| Slow feedback inhibition in the CA3 area of the rat hippocampus by synergistic synaptic activation of mGluR1 and mGluR5. | Mori M et al. | β | 2002 | β |
| State-dependent heterogeneity in synaptic depression between pyramidal cell pairs. | Montgomery JM et al. | β | 2002 | β |
| Synaptic plasticity in the acoustic startle pathway: the neuronal basis for short-term habituation? | Weber M et al. | β | 2002 | β |
| Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. | Kitano J et al. | β | 2002 | β |
| The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7. | Enz R | β | 2002 | β |
| The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala. | Rodrigues SM et al. | β | 2002 | β |
| The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP: evidence for a strong reduction of Ca2+ entry in single nerve terminals. | MillΓ‘n C et al. | β | 2002 | β |
| The metabotropic glutamate receptor mGluR7b binds to the catalytic gamma-subunit of protein phosphatase 1. | Enz R | β | 2002 | β |
| The pharmacological manipulation of glutamate receptors and neuroprotection. | Stone TW et al. | β | 2002 | β |
| The striatum as a target for anti-rigor effects of an antagonist of mGluR1, but not an agonist of group II metabotropic glutamate receptors. | Ossowska K et al. | β | 2002 | β |
| Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes. | Benquet P et al. | β | 2002 | β |
| Type I and II metabotropic glutamate receptors modulate periaqueductal grey glycine release: interaction between mGlu2/3 and A1 adenosine receptors. | de Novellis V et al. | β | 2002 | β |
| Variation of CS salience reveals group II mGluR-dependent and -independent forms of conditioning in the rat. | Riedel G et al. | β | 2002 | β |
| Activation of group II metabotropic glutamate receptors results in long-term potentiation following preconditioning stimulation in the dentate gyrus. | Rush AM et al. | β | 2001 | β |
| Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking. | Lan JY et al. | β | 2001 | β |
| Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1. | Kew JN et al. | β | 2001 | β |
| An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors. | Bruno V et al. | β | 2001 | β |
| Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. | Chapman AG et al. | β | 2001 | β |
| beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. | Lea PM et al. | β | 2001 | β |
| Changes in metabotropic glutamate receptor expression following spinal cord injury. | Mills CD et al. | β | 2001 | β |
| Cocaine-responsive gene expression changes in rat hippocampus. | Freeman WM et al. | β | 2001 | β |
| Coordinate regulation of metabotropic glutamate receptors. | Alagarsamy S et al. | β | 2001 | β |
| Cyclic AMP-dependent protein kinase phosphorylates group III metabotropic glutamate receptors and inhibits their function as presynaptic receptors. | Cai Z et al. | β | 2001 | β |
| D4 dopamine and metabotropic glutamate receptors in cerebral cortex and striatum in rat brain. | Berger MA et al. | β | 2001 | β |
| Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites. | Tamaru Y et al. | β | 2001 | β |
| Expression of metabotropic glutamate receptor 1alpha in the hippocampus of rat pilocarpine model of status epilepticus. | Tang FR et al. | β | 2001 | β |
| Expression of the group II and III metabotropic glutamate receptors in the hippocampus of patients with mesial temporal lobe epilepsy. | Tang FR et al. | β | 2001 | β |
| Expression of the group I metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy. | Tang FR et al. | β | 2001 | β |
| Fast synaptic transmission mediated by P2X receptors in CA3 pyramidal cells of rat hippocampal slice cultures. | Mori M et al. | β | 2001 | β |
| Frequency dependence of endocytosis in aortic baroreceptor neurons and role of group III mGluRs. | Pamidimukkala J et al. | β | 2001 | β |
| Glutamate receptor involvement in dentate granule cell epileptiform activity evoked by mossy fiber stimulation. | Okazaki MM et al. | β | 2001 | β |
| Glutamate receptor subunit expression in primary neuronal and secondary glial cultures. | Janssens N et al. | β | 2001 | β |
| Hippocampal mossy fibers induce assembly and clustering of PSD95-containing postsynaptic densities independent of glutamate receptor activation. | Qin L et al. | β | 2001 | β |
| Immunocytochemical localization of GABA(B) receptors in mesencephalic trigeminal nucleus neurons in the rat. | Li JL et al. | β | 2001 | β |
| Immunocytochemical localization of metabotropic glutamate receptor type 1 alpha and tubulin in rat brain. | LujΓ‘n R et al. | β | 2001 | β |
| Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7. | Sansig G et al. | β | 2001 | β |
| Intensity-dependent, rapid activation of presynaptic metabotropic glutamate receptors at a central synapse. | Awatramani GB et al. | β | 2001 | β |
| Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat. | Mills CD et al. | β | 2001 | β |
| Localization of the human mGluR4 gene within an epilepsy susceptibility locus(1). | Wong CG et al. | β | 2001 | β |
| Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. | Mannaioni G et al. | β | 2001 | β |
| Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices. | Saransaari P et al. | β | 2001 | β |
| Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. | Bruno V et al. | β | 2001 | β |
| Metabotropic glutamate receptor type 1alpha and tubulin assemble into dynamic interacting complexes. | Ciruela F et al. | β | 2001 | β |
| Modulation of spontaneous quantal release of neurotransmitters in the hippocampus. | Bouron A | β | 2001 | β |
| Molecular heterogeneity of central synapses: afferent and target regulation. | Craig AM et al. | β | 2001 | β |
| Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses. | Walker MC et al. | β | 2001 | β |
| NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance. | Zhao J et al. | β | 2001 | β |
| Neuronal plasticity in hippocampal mossy fiber-CA3 synapses of mice lacking the inositol-1,4,5-trisphosphate type 1 receptor. | Itoh S et al. | β | 2001 | β |
| Pharmacology and neuroprotective actions of mGlu receptor ligands. | O'Neill MJ | β | 2001 | β |
| PKC phosphorylation of a conserved serine residue in the C-terminus of group III metabotropic glutamate receptors inhibits calmodulin binding. | Airas JM et al. | β | 2001 | β |
| Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia. | Bolonna AA et al. | β | 2001 | β |
| Postsynaptic calcium transients evoked by activation of individual hippocampal mossy fiber synapses. | Reid CA et al. | β | 2001 | β |
| Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. | TatarczyΕska E et al. | β | 2001 | β |
| Presynaptic group II mGluR inhibition of short-term depression in the medial perforant path of the dentate gyrus in vitro. | Kilbride J et al. | β | 2001 | β |
| Role of excitatory amino acids in developmental epilepsies. | Raol YH et al. | β | 2001 | β |
| Spinal interneuronal systems: identification, multifunctional character and reconfigurations in mammals. | Jankowska E | β | 2001 | β |
| Synaptically activated calcium responses in dendrites of hippocampal oriens-alveus interneurons. | Gee CE et al. | β | 2001 | β |
| The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia. | McCarthy JB et al. | β | 2001 | β |
| Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia Nigra pars reticulata. | Bradley SR et al. | β | 2000 | β |
| Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes. | Shinomura T et al. | β | 2000 | β |
| Activation of presynaptic group III metabotropic receptors enhances glutamate release in rat entorhinal cortex. | Evans DI et al. | β | 2000 | β |
| Activity-dependent activation of presynaptic metabotropic glutamate receptors in locus coeruleus. | DubΓ© GR et al. | β | 2000 | β |
| Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists. | Izumi Y et al. | β | 2000 | β |
| Associative long-term depression in the hippocampus is dependent on postsynaptic N-type Ca2+ channels. | Normann C et al. | β | 2000 | β |
| cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation. | Schaffhauser H et al. | β | 2000 | β |
| Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. | Mutel V et al. | β | 2000 | β |
| Coincident activation of mGluRs and mAChRs imposes theta frequency patterning on synchronised network activity in the hippocampal CA3 region. | Cobb SR et al. | β | 2000 | β |
| Constraints on proper folding of the amino terminal domains of group III metabotropic glutamate receptors. | Peltekova V et al. | β | 2000 | β |
| Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus. | Cohen I et al. | β | 2000 | β |
| Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1. | Tsuji Y et al. | β | 2000 | β |
| Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation. | Ango F et al. | β | 2000 | β |
| Developmental regulation of hippocampal excitatory synaptic transmission by metabotropic glutamate receptors. | Ross FM et al. | β | 2000 | β |
| Development and molecular organization of dendritic spines and their synapses. | Zhang W et al. | β | 2000 | β |
| Differential effects of the group II mGluR agonist, DCG-IV, on depolarization-induced suppression of inhibition in hippocampal CA1 and CA3 neurons. | Morishita W et al. | β | 2000 | β |
| Differential mechanisms of transmission at three types of mossy fiber synapse. | Toth K et al. | β | 2000 | β |
| Distinct inhibition of acute cocaine-stimulated motor activity following microinjection of a group III metabotropic glutamate receptor agonist into the dorsal striatum of rats. | Mao L et al. | β | 2000 | β |
| Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures. | Ulas J et al. | β | 2000 | β |
| Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. | Neugebauer V et al. | β | 2000 | β |
| Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function. | Ciruela F et al. | β | 2000 | β |
| Induction of homosynaptic long-term depression at spinal synapses of sensory a delta-fibers requires activation of metabotropic glutamate receptors. | Chen J et al. | β | 2000 | β |
| Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1. | El Far O et al. | β | 2000 | β |
| Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus. | Saransaari P et al. | β | 2000 | β |
| (+)-MCPG induces PKCepsilon translocation in cortical synaptosomes through a PLD-coupled mGluR. | Pastorino L et al. | β | 2000 | β |
| Metabotropic glutamate receptor subtypes are differentially expressed after transient cerebral ischemia without, during and after tolerance induction in the gerbil hippocampus. | Sommer C et al. | β | 2000 | β |
| Modest increase in extracellular potassium unmasks effect of recurrent mossy fiber growth. | Hardison JL et al. | β | 2000 | β |
| Modulation of absence seizures by the GABA(A) receptor: a critical rolefor metabotropic glutamate receptor 4 (mGluR4). | Snead OC et al. | β | 2000 | β |
| Modulation of calcium channels by group I and group II metabotropic glutamate receptors in dentate gyrus neurons from patients with temporal lobe epilepsy. | Schumacher TB et al. | β | 2000 | β |
| Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors. | Semyanov A et al. | β | 2000 | β |
| N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system. | Neale JH et al. | β | 2000 | β |
| N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors. | Cambonie G et al. | β | 2000 | β |
| No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study. | Goodwin H et al. | β | 2000 | β |
| PICK1 interacts with and regulates PKC phosphorylation of mGLUR7. | Dev KK et al. | β | 2000 | β |
| Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site. | Boudin H et al. | β | 2000 | β |
| Region-specific decline in the expression of metabotropic glutamate receptor 7 mRNA in rat brain during aging. | Simonyi A et al. | β | 2000 | β |
| Regulation of neurotransmitter release by metabotropic glutamate receptors. | Cartmell J et al. | β | 2000 | β |
| Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death. | Bruno V et al. | β | 2000 | β |
| Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice. | Popik P et al. | β | 2000 | β |
| Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons. | Perroy J et al. | β | 2000 | β |
| Synaptic control of motoneuronal excitability. | Rekling JC et al. | β | 2000 | β |
| Synaptic relationship of the neurons containing a metabotropic glutamate receptor, MGluR5, with nociceptive primary afferent and GABAergic terminals in rat spinal superficial laminae. | Tao YX et al. | β | 2000 | β |
| Target-specific expression of pre- and postsynaptic mechanisms. | TΓ³th K et al. | β | 2000 | β |
| Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: correlated changes in mGluR1 mRNA and protein expression in experimental animals and human patients. | BlΓΌmcke I et al. | β | 2000 | β |
| The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat. | Dawson L et al. | β | 2000 | β |
| The multifarious hippocampal mossy fiber pathway: a review. | Henze DA et al. | β | 2000 | β |
| Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. | Aronica E et al. | β | 2000 | β |
| Up-regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability. | Lie AA et al. | β | 2000 | β |
| 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist. | Gasparini F et al. | β | 1999 | β |
| Activation of mGluRII induces LTD via activation of protein kinase A and protein kinase C in the dentate gyrus of the hippocampus in vitro. | Huang L et al. | β | 1999 | β |
| Analysing metabotropic glutamate group III receptor mediated modulation of synaptic transmission in the amygdala-kindled dentate gyrus of the rat. | Friedl M et al. | β | 1999 | β |
| Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S)-4-phosphonophenylglycine. | Chapman AG et al. | β | 1999 | β |
| A relationship between protein kinase C phosphorylation and calmodulin binding to the metabotropic glutamate receptor subtype 7. | Nakajima Y et al. | β | 1999 | β |
| Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxy-terminal domains. | Stowell JN et al. | β | 1999 | β |
| Biochemical and electrophysiological studies on (S)-(+)-2-(3'-carboxybicyclo(1.1.1)pentyl)-glycine (CBPG), a novel mGlu5 receptor agonist endowed with mGlu1 receptor antagonist activity. | Mannaioni G et al. | β | 1999 | β |
| Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling. | O'Connor V et al. | β | 1999 | β |
| Cell surface expression of the metabotropic glutamate receptor type 1alpha is regulated by the C-terminal tail. | Ciruela F et al. | β | 1999 | β |
| Co-expression of metabotropic glutamate receptor type 1alpha with homer-1a/Vesl-1S increases the cell surface expression of the receptor. | Ciruela F et al. | β | 1999 | β |
| Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling. | Klapstein GJ et al. | β | 1999 | β |
| Developmental expression of the group III metabotropic glutamate receptor mGluR4a in the medial nucleus of the trapezoid body of the rat. | Elezgarai I et al. | β | 1999 | β |
| Distinct subtypes of metabotropic glutamate receptors mediate differential actions on excitability of spinal respiratory motoneurons. | Dong XW et al. | β | 1999 | β |
| Distribution of the group II metabotropic glutamate receptors (mGluR2/3) in the enteric nervous system of the rat. | Larzabal A et al. | β | 1999 | β |
| Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission. | Sakaguchi G et al. | β | 1999 | β |
| Dual mechanism for presynaptic modulation by axonal metabotropic glutamate receptor at the mouse mossy fibre-CA3 synapse. | Kamiya H et al. | β | 1999 | β |
| Effect of the group II metabotropic glutamate agonist, 2R,4R-APDC, varies with age, layer, and visual experience in the visual cortex. | Beaver CJ et al. | β | 1999 | β |
| Evidence for endogenous excitatory amino acids as mediators in DSI of GABA(A)ergic transmission in hippocampal CA1. | Morishita W et al. | β | 1999 | β |
| Evidence for involvement of group II/III metabotropic glutamate receptors in NMDA receptor-independent long-term potentiation in area CA1 of rat hippocampus. | Grover LM et al. | β | 1999 | β |
| G-protein-independent signaling mediated by metabotropic glutamate receptors. | Heuss C et al. | β | 1999 | β |
| Group III metabotropic glutamate receptors control corticothalamic synaptic transmission in the rat thalamus in vitro. | Turner JP et al. | β | 1999 | β |
| Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection. | Nicoletti F et al. | β | 1999 | β |
| Identification, cloning and analysis of expression of a new alternatively spliced form of the metabotropic glutamate receptor mGluR1 mRNA1. | Soloviev MM et al. | β | 1999 | β |
| Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia. | Bradley SR et al. | β | 1999 | β |
| Immunohistological studies of metabotropic glutamate receptor subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation. | Tagawa Y et al. | β | 1999 | β |
| Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro. | Huang L et al. | β | 1999 | β |
| Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro. | Camodeca N et al. | β | 1999 | β |
| Interactions of the C terminus of metabotropic glutamate receptor type 1alpha with rat brain proteins: evidence for a direct interaction with tubulin. | Ciruela F et al. | β | 1999 | β |
| Interactions of the C Terminus of Metabotropic Glutamate Receptor Type 1Ξ± with Rat Brain Proteins: Evidence for a Direct Interaction with Tubulin. | Ciruela F et al. | β | 1999 | β |
| Involvement of metabotropic glutamate receptors in taurine release in the adult and developing mouse hippocampus. | Saransaari P et al. | β | 1999 | β |
| Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering. | Tadokoro S et al. | β | 1999 | β |
| Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor. | Han G et al. | β | 1999 | β |
| Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. | Kosinski CM et al. | β | 1999 | β |
| Localization of the brain-specific high-affinity l-proline transporter in cultured hippocampal neurons: molecular heterogeneity of synaptic terminals. | Crump FT et al. | β | 1999 | β |
| Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events. | Laezza F et al. | β | 1999 | β |
| Metabotropic glutamate receptor activation and blockade: their role in long-term potentiation, learning and neurotoxicity. | HΓΆlscher C et al. | β | 1999 | β |
| Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. | Anwyl R | β | 1999 | β |
| Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn. | Jia H et al. | β | 1999 | β |
| Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion. | Masugi M et al. | β | 1999 | β |
| mGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats. | Schools GP et al. | β | 1999 | β |
| mGluR7-like metabotropic glutamate receptors inhibit NMDA-mediated excitotoxicity in cultured mouse cerebellar granule neurons. | Lafon-Cazal M et al. | β | 1999 | β |
| mGluR7-like receptor and GABA(B) receptor activation enhance neurotoxic effects of N-methyl-D-aspartate in cultured mouse striatal GABAergic neurones. | Lafon-Cazal M et al. | β | 1999 | β |
| Modulation of synaptic transmission and differential localisation of mGlus in cultured hippocampal autapses. | Bushell TJ et al. | β | 1999 | β |
| Molecular neuropathology of human mesial temporal lobe epilepsy. | BlΓΌmcke I et al. | β | 1999 | β |
| Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism. | Yeckel MF et al. | β | 1999 | β |
| Predominant expression of group-II metabotropic glutamate receptors in the goldfish brain. | Poli A et al. | β | 1999 | β |
| Probing the ligand-binding domain of the mGluR4 subtype of metabotropic glutamate receptor. | Hampson DR et al. | β | 1999 | β |
| Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms. | Pellegrini-Giampietro DE et al. | β | 1999 | β |
| Reduced function of L-AP4-sensitive metabotropic glutamate receptors in human epileptic sclerotic hippocampus. | Dietrich D et al. | β | 1999 | β |
| Role of metabotropic glutamate receptors in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal. | Suzuki T et al. | β | 1999 | β |
| Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus. | Bortolotto ZA et al. | β | 1999 | β |
| The arrangement of glutamate receptors in excitatory synapses. | Takumi Y et al. | β | 1999 | β |
| Afferent-specific innervation of two distinct AMPA receptor subtypes on single hippocampal interneurons. | TΓ³th K et al. | β | 1998 | β |
| Autoradiographic visualization of group III metabotropic glutamate receptors using [3H]-L-2-amino-4-phosphonobutyrate. | Hudtloff C et al. | β | 1998 | β |
| Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8. | Corti C et al. | β | 1998 | β |
| Coexpression of multiple metabotropic glutamate receptors in axon terminals of single suprachiasmatic nucleus neurons. | Chen G et al. | β | 1998 | β |
| Differential regulation of synaptic inputs to dentate hilar border interneurons by metabotropic glutamate receptors. | Doherty J et al. | β | 1998 | β |
| Dynamics of excitatory transmitter release: analysis of synaptic responses in CA3 hippocampal neurons after repetitive stimulation of afferent fibers. | Canepari M et al. | β | 1998 | β |
| Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1. | Morishita W et al. | β | 1998 | β |
| GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus. | AcsΓ‘dy L et al. | β | 1998 | β |
| Immunohistochemical localisation of mGluR7 protein in the rodent and human cerebellar cortex using subtype specific antibodies. | Phillips T et al. | β | 1998 | β |
| Immunohistochemical localization of the mGluR1beta metabotropic glutamate receptor in the adult rodent forebrain: evidence for a differential distribution of mGluR1 splice variants. | Ferraguti F et al. | β | 1998 | β |
| Metabotropic glutamate receptor subtypes in axon terminals of projection fibers from the main and accessory olfactory bulbs: a light and electron microscopic immunohistochemical study in the rat. | Wada E et al. | β | 1998 | β |
| Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions. | Vizi ES et al. | β | 1998 | β |
| Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. | Bruno V et al. | β | 1998 | β |
| Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV. | Kilbride J et al. | β | 1998 | β |
| Priming of group 2 metabotropic glutamate receptors facilitates induction of long-term depression in the dentate gyrus of freely moving rats. | Manahan-Vaughan D | β | 1998 | β |
| Priming of long-term potentiation by prior activation of group I and II metabotropic glutamate receptors in the rat dentate gyrus in vitro. | O'Leary DM et al. | β | 1998 | β |
| Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins. | Macek TA et al. | β | 1998 | β |
| Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice. | Thomsen C et al. | β | 1998 | β |
| Salient features of synaptic organisation in the cerebral cortex. | Somogyi P et al. | β | 1998 | β |
| Structural basis for a Ca2+-sensing function of the metabotropic glutamate receptors. | Kubo Y et al. | β | 1998 | β |
| Switch from facilitation to inhibition of excitatory synaptic transmission by group I mGluR desensitization. | RodrΓguez-Moreno A et al. | β | 1998 | β |
| Target-specific expression of presynaptic mossy fiber plasticity. | Maccaferri G et al. | β | 1998 | β |
| The group III metabotropic glutamate receptor agonist, l-AP4, reduces EPSPs in some layers of rat visual cortex. | Jin X et al. | β | 1998 | β |
| The metabotropic glutamate receptor 1 is not involved in the facilitation of glutamate release in cerebrocortical nerve terminals. | Sistiaga A et al. | β | 1998 | β |
| The role of group II metabotropic glutamate receptors in hippocampal CA1 long-term potentiation in vitro. | Behnisch T et al. | β | 1998 | β |
| Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. | Shigemoto R et al. | β | 1997 | β |
| Two forms of hippocampal long-term depression, the counterpart of long-term potentiation. | Manabe T | β | 1997 | β |