Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders.
paper
Cited
Public
Unavailable
- Authors
- Chabot, R J; Orgill, A A; Crawford, G; Harris, M J; Serfontein, G
- Year
- 1999
- Journal
- Journal of child neurology
- PMID
- 10385840
- DOI
- 10.1177/088307389901400601
Behavioral and quantitative electroencephalography (EEG) techniques were used to evaluate treatment response to stimulant therapy in children with attention disorders. A sample of 130 children with attention disorders were evaluated with Conners and Diagnostic and Statistical Manual of Mental Disorders--III rating scales, and with neurometric quantitative EEG before and 6 to 14 months after treatment with stimulants. Significant quantitative EEG differences were found between the normal control population (N = 31) and the children with attention problems. Quantitative EEG abnormalities involved increased theta or alpha power, greatest in frontal regions, frontal theta/alpha hypercoherence, and posterior interhemispheric power asymmetry. Behavioral improvement after stimulant treatment was seen in 81.5% of the children with attention-deficit hyperactivity disorder and 44.7% of the children with attention-deficit disorder, with the degree of correspondence between behavioral and quantitative EEG changes at 78.5%. Pretreatment clinical and quantitative EEG features could predict treatment response with a sensitivity of 83.1% and a specificity of 88.2%. A combined behavioral and quantitative EEG approach can be useful for following and predicting treatment response to stimulants in children with attention disorders.
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| Title | Year | PMID |
|---|---|---|
| Advances in Electrophysiological Research. | 2015 | 26259089 |
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
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| ADHD and Differences in Brain Function as Measured by EEG: Cause or Effect? | Ahn K et al. | — | 2025 | → |
| Challenging the Diagnostic Value of Theta/Beta Ratio: Insights From an EEG Subtyping Meta-Analytical Approach in ADHD. | Boxum M et al. | — | 2025 | → |
| Electrophysiological and Clinical Predictors of Methylphenidate, Guanfacine, and Combined Treatment Outcomes in Children With Attention-Deficit/Hyperactivity Disorder. | Michelini G et al. | — | 2023 | → |
| A Case Study on EEG Analysis: Embedding Entropy Estimations Indicate the Decreased Neuro-Cortical Complexity Levels Mediated by Methylphenidate Treatment in Children with ADHD. | Çetin FH et al. | — | 2022 | → |
| Target to treatment: A charge to develop biomarkers of response and tolerability in child and adolescent psychiatry. | Stancil SL et al. | — | 2022 | → |
| Toward Precision Medicine in ADHD. | Buitelaar J et al. | — | 2022 | → |
| Effect of anti-attention-deficit hyperactivity disorder (ADHD) medication on clinical seizures and sleep EEG: A retrospective study of Japanese children with ADHD. | Yamamoto H et al. | — | 2021 | → |
| Peripheral biomarkers of attention-deficit hyperactivity disorder: Current status and future perspective. | Takahashi N et al. | — | 2021 | → |
| Quantitative EEG in Childhood Attention Deficit Hyperactivity Disorder and Learning Disabilities. | Chiarenza GA | — | 2021 | → |
| Resting state EEG power research in Attention-Deficit/Hyperactivity Disorder: A review update. | Clarke AR et al. | — | 2020 | → |
| An EEG Investigation of the Attention-Related Impact of Mindfulness Training in Youth With ADHD: Outcomes and Methodological Considerations. | Sibalis A et al. | — | 2019 | → |
| A systematic review of quantitative EEG as a possible biomarker in child psychiatric disorders. | McVoy M et al. | — | 2019 | → |
| Measuring Treatment Response in Pharmacological and Lifestyle Interventions Using Electroencephalography in ADHD: A Review. | Kirkland AE et al. | — | 2019 | → |
| Multimodal Neuroimaging: Basic Concepts and Classification of Neuropsychiatric Diseases. | Tulay EE et al. | — | 2019 | → |
| Predicting Clinical Gains and Side Effects of Stimulant Medication in Pediatric Attention-Deficit/Hyperactivity Disorder by Combining Measures From qEEG and ERPs in a Cued GO/NOGO Task. | Ogrim G et al. | — | 2019 | → |
| Predictive Value of Slow and Fast EEG Oscillations for Methylphenidate Response in ADHD. | Sari Gokten E et al. | — | 2019 | → |
| Evaluation of Two Types of Drug Treatment with QEEG in Children with ADHD. | Aldemir R et al. | — | 2018 | → |
| Junior temperament character inventory together with quantitative EEG discriminate children with attention deficit hyperactivity disorder combined subtype from children with attention deficit hyperactivity disorder combined subtype plus oppositional defiant disorder. | Chiarenza GA et al. | — | 2018 | → |
| Semi-Automated Biomarker Discovery from Pharmacodynamic Effects on EEG in ADHD Rodent Models. | Yokota T et al. | — | 2018 | → |
| An Investigation of Stimulant Effects on the EEG of Children With Attention-Deficit/Hyperactivity Disorder. | Clarke AR et al. | — | 2017 | → |
| Coherence in children with AD/HD and excess alpha power in their EEG. | Robbie JC et al. | — | 2016 | → |
| Single-dose effects on the P3no-go ERP component predict clinical response to stimulants in pediatric ADHD. | Ogrim G et al. | — | 2016 | → |
| The quantified EEG characteristics of responders and non-responders to long-term treatment with atomoxetine in children with attention deficit hyperactivity disorders. | Chiarenza GA et al. | — | 2016 | → |
| Advances in Electrophysiological Research. | Kamarajan C et al. | — | 2015 | → |
| Personalized Medicine: Review and Perspectives of Promising Baseline EEG Biomarkers in Major Depressive Disorder and Attention Deficit Hyperactivity Disorder. | Olbrich S et al. | — | 2015 | → |
| Baduk (the Game of Go) Improved Cognitive Function and Brain Activity in Children with Attention Deficit Hyperactivity Disorder. | Kim SH et al. | — | 2014 | → |
| Neurophysiologic predictors of response to atomoxetine in young adults with attention deficit hyperactivity disorder: a pilot project. | Leuchter AF et al. | — | 2014 | → |
| Personalized Medicine in ADHD and Depression: Use of Pharmaco-EEG. | Arns M et al. | — | 2014 | → |
| Predicting the clinical outcome of stimulant medication in pediatric attention-deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a go/no-go test. | Ogrim G et al. | — | 2014 | → |
| The EEG as an index of neuromodulator balance in memory and mental illness. | Vakalopoulos C | — | 2014 | → |
| A proposed multisite double-blind randomized clinical trial of neurofeedback for ADHD: need, rationale, and strategy. | Kerson C et al. | — | 2013 | → |
| Effectiveness of EEG-Biofeedback on Attentiveness, Working Memory and Quantitative Electroencephalography on Reading Disorder. | Mosanezhad Jeddi E et al. | — | 2013 | → |
| Excess beta activity in the EEG of children with attention-deficit/hyperactivity disorder: a disorder of arousal? | Clarke AR et al. | — | 2013 | → |
| Performance analysis of univariate and multivariate EEG measurements in the diagnosis of ADHD. | González JJ et al. | — | 2013 | → |
| The effects of QEEG-informed neurofeedback in ADHD: an open-label pilot study. | Arns M et al. | — | 2012 | → |
| Behavioural differences between EEG-defined subgroups of children with Attention-Deficit/Hyperactivity Disorder. | Clarke AR et al. | — | 2011 | → |
| Electrophysiological markers of genetic risk for attention deficit hyperactivity disorder. | Tye C et al. | — | 2011 | → |
| Neurofeedback in ADHD: a single-blind randomized controlled trial. | Bakhshayesh AR et al. | — | 2011 | → |
| EEG-vigilance and response to stimulants in paediatric patients with attention deficit/hyperactivity disorder. | Sander C et al. | — | 2010 | → |
| Introduction. | Walker JE | — | 2010 | → |
| Predicting methylphenidate response in long-term survivors of childhood cancer: a randomized, double-blind, placebo-controlled, crossover trial. | Conklin HM et al. | — | 2010 | → |
| The need for individualization in neurofeedback: heterogeneity in QEEG patterns associated with diagnoses and symptoms. | Hammond DC | — | 2010 | → |
| Acute atomoxetine effects on the EEG of children with attention-deficit/hyperactivity disorder. | Barry RJ et al. | — | 2009 | → |
| EEG coherence in children with attention-deficit/hyperactivity disorder and comorbid reading disabilities. | Barry RJ et al. | — | 2009 | → |
| QEEG studies in the assessment and treatment of childhood disorders. | Cantor DS et al. | — | 2009 | → |
| EEG coherence in girls with attention-deficit/hyperactivity disorder: stimulant effects in good responders. | Dupuy FE et al. | — | 2008 | → |
| EEG phenotypes predict treatment outcome to stimulants in children with ADHD. | Arns M et al. | — | 2008 | → |
| Effects of imipramine hydrochloride on the EEG of children with Attention-Deficit/Hyperactivity Disorder who are non-responsive to stimulants. | Clarke AR et al. | — | 2008 | → |
| Quantitative electroencephalography and attention-deficit/hyperactivity disorder: implications for clinical practice. | Monastra VJ | — | 2008 | → |
| EEG coherence in children with attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder. | Barry RJ et al. | — | 2007 | → |
| Effects of stimulant medications on the EEG of girls with Attention-Deficit/Hyperactivity Disorder. | Clarke AR et al. | — | 2007 | → |
| Electrophysiological subtypes of psychotic states. | John ER et al. | — | 2007 | → |
| Evaluation of the effect of methylphenidate by computed tomography, electroencephalography, neuropsychological tests, and clinical symptoms in children with attention-deficit/hyperactivity disorder: A prospective cohort study. | Yildiz Oc O et al. | — | 2007 | → |
| Age and gender effects in EEG coherence: III. Girls with attention-deficit/hyperactivity disorder. | Barry RJ et al. | — | 2006 | → |
| A meta-analysis of quantitative EEG power associated with attention-deficit hyperactivity disorder. | Snyder SM et al. | — | 2006 | → |
| Attention deficit disorders: are we barking up the wrong tree? | Cabral P | — | 2006 | → |
| Attention deficit hyperactivity disorder. | Kuntsi J et al. | — | 2006 | → |
| Attention-deficit/hyperactivity disorder: neurophysiology, information processing, arousal and drug development. | Rowe DL et al. | — | 2006 | → |
| Integrative neuroscience approach to predict ADHD stimulant response. | Hermens DF et al. | — | 2006 | → |
| Pharmaco-EEG in psychiatry. | Mucci A et al. | — | 2006 | → |
| The value of quantitative electroencephalography in clinical psychiatry: a report by the Committee on Research of the American Neuropsychiatric Association. | Coburn KL et al. | — | 2006 | → |
| A four-step approach for developing diagnostic tests in psychiatry: EEG in ADHD as a test case. | Boutros N et al. | — | 2005 | → |
| Age and gender effects in EEG coherence: II. Boys with attention deficit/hyperactivity disorder. | Barry RJ et al. | — | 2005 | → |
| Effects of methylphenidate on EEG coherence in attention-deficit/hyperactivity disorder. | Clarke AR et al. | — | 2005 | → |
| Electroencephalographic biofeedback in the treatment of attention-deficit/hyperactivity disorder. | Monastra VJ et al. | — | 2005 | → |
| Event-related potentials in attention-deficit/hyperactivity disorder of the predominantly inattentive type: an investigation of EEG-defined subtypes. | Brown CR et al. | — | 2005 | → |
| Neural substrates of childhood attention-deficit/hyperactivity disorder: electroencephalographic and magnetic resonance imaging evidence. | Willis WG et al. | — | 2005 | → |
| Overcoming the barriers to effective treatment for attention-deficit/hyperactivity disorder: a neuro-educational approach. | Monastra VJ | — | 2005 | → |
| Stimulant drug action in attention deficit hyperactivity disorder (ADHD): inference of neurophysiological mechanisms via quantitative modelling. | Rowe DL et al. | — | 2005 | → |
| The effect of methylphenidate on response inhibition and the event-related potential of children with attention deficit/hyperactivity disorder. | Broyd SJ et al. | — | 2005 | → |
| The neurophysiology of attention-deficit/hyperactivity disorder. | di Michele F et al. | — | 2005 | → |
| The role of quantitative electroencephalography in child and adolescent psychiatric disorders. | Chabot RJ et al. | — | 2005 | → |
| Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: importance and cautions. | Prichep LS | — | 2005 | → |
| Attention-deficit hyperactivity disorder (ADHD). | Voeller KK | — | 2004 | → |
| The usefulness of quantitative EEG (QEEG) and neurotherapy in the assessment and treatment of post-concussion syndrome. | Duff J | — | 2004 | → |
| Aiding diagnosis of attention-deficit/hyperactivity disorder and its subtypes: discriminant function analysis of event-related potential data. | Smith JL et al. | — | 2003 | → |
| A review of electrophysiology in attention-deficit/hyperactivity disorder: I. Qualitative and quantitative electroencephalography. | Barry RJ et al. | — | 2003 | → |
| EEG activity in girls with attention-deficit/hyperactivity disorder. | Clarke AR et al. | — | 2003 | → |
| EEG biofeedback vs. placebo treatment for attention-deficit/hyperactivity disorder: a pilot study. | Heywood C et al. | — | 2003 | → |
| Effects of stimulant medications on children with attention-deficit/hyperactivity disorder and excessive beta activity in their EEG. | Clarke AR et al. | — | 2003 | → |
| Effects of stimulant medications on the EEG of children with Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive type. | Clarke AR et al. | — | 2003 | → |
| EEG differences between good and poor responders to methylphenidate and dexamphetamine in children with attention-deficit/hyperactivity disorder. | Clarke AR et al. | — | 2002 | → |
| Epileptiform abnormalities in children with attention-deficit-hyperactivity disorder. | Richer LP et al. | — | 2002 | → |
| Rates of adherence to pharmacological treatment among children and adolescents with attention deficit hyperactivity disorder. | Ibrahim el SR | — | 2002 | → |
| 3D statistical parametric mapping of EEG source spectra by means of variable resolution electromagnetic tomography (VARETA). | Bosch-Bayard J et al. | — | 2001 | → |
| EEG-defined subtypes of children with attention-deficit/hyperactivity disorder. | Clarke AR et al. | — | 2001 | → |
| The clinical role of computerized EEG in the evaluation and treatment of learning and attention disorders in children and adolescents. | Chabot RJ et al. | — | 2001 | → |