The genetics of alcoholisms and related disorders.
- Authors
- Bohman, M; Cloninger, R; Sigvardsson, S; von Knorring, A L
- Year
- 1987
- Journal
- Journal of psychiatric research
- PMID
- 3326937
- DOI
- 10.1016/0022-3956(87)90092-6
The inheritance of alcohol abuse and other psychopathology in 862 men and 913 women adopted by non-relatives, was studied. Both male and female adoptees were at greater risk to develop alcohol abuse if their biological, but not their adoptive, parents were alcoholic. Three types of families with alcoholism were distinguished that differed in frequency of alcohol abuse, somatoform disorders in women and in relation to antisocial behaviour in male adoptees. The combination of both genetic and environmental risk factors was necessary for the development of alcoholism in the most common, milieu-limited type of alcoholism. In families with a less common, male-limited, type of vulnerability, alcohol abuse was highly heritable in men, but women had multiple somatic complaints and seldom abuse. In a third type of family the common vulnerability was expressed as antisocial behavior with violent criminality and recurrent alcohol abuse in males, but as high frequency somatization in female relatives.
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In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Understanding alcohol use disorders with neuroelectrophysiology. | 2014 | 25307587 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity. | Pandey G et al. | — | 2020 | → |
| Gender Differentiation of Indirect Self-Destructiveness in Drug Addicted Individuals (Indirect Self-Destructiveness in Addicted Women and Men). | Tsirigotis K | — | 2019 | → |
| Emergence of sex differences in the development of substance use and abuse during adolescence. | Kuhn C | — | 2015 | → |
| Translational clinical neuroscience perspectives on the cognitive and neurobiological mechanisms underlying alcohol-related aggression. | Beck A et al. | — | 2014 | → |
| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | — | 2014 | → |
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