Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).
- Authors
- Cubells, Joseph F; Feinn, Richard; Pearson, Deborah; Burda, Jeffrey; Tang, Yilang; Farrer, Lindsay A; Gelernter, Joel; Kranzler, Henry R
- Year
- 2005
- Journal
- Drug and alcohol dependence
- PMID
- 15894433
- DOI
- 10.1016/j.drugalcdep.2005.03.019
BACKGROUND: Cocaine can induce transient psychotic symptoms. We examined the phenomenology of such cocaine-induced psychosis (CIP) using a modified version of the Scale for Assessment of Positive Symptoms (SAPS), a well-validated instrument for the assessment of schizophrenic psychosis. METHODS: We developed a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP), based on the well-validated SAPS. We interviewed 243 unrelated cocaine-dependent adults using both the SAPS-CIP and an instrument for the identification of cocaine-induced paranoia, the Cocaine Experience Questionnaire (CEQ). RESULTS: One hundred and eighty-one (75%) of the subjects endorsed CIP using the CEQ. With the SAPS-CIP, hallucination (HAL) and delusion (DEL) scores correlated strongly, and the DEL domain showed excellent concurrent validity with the CEQ. We observed significant positive correlations, respectively, between severity of HAL and DEL, and lifetime number of episodes of cocaine use, and negative correlations with age at onset of cocaine use. CONCLUSIONS: The results suggest that CIP consists of transient delusional and hallucinatory symptoms, which tend to occur together and co-vary in severity. It appears that rating cocaine-induced paranoia alone (e.g., with the CEQ) can identify most subjects experiencing CIP. However, the SAPS-CIP is useful for quantifying the severity of CIP according to operational criteria. Our data provide additional evidence that CIP is a sensitizing response.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| New Evidence of The Reliability of The <i>Scale for The Assessment of Positive Symptoms of Cocaine Induced Psychosis</i> (SAPS-CIP-R) in a Sample of Cocaine Users Treated at a Therapeutic Community. | González-Saiz F et al. | — | 2026 | → |
| USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder. | Cheron J et al. | — | 2023 | → |
| USP7/Maged1-Mediated H2A Monoubiquitination in the Paraventricular Thalamus: An Epigenetic Mechanism Involved in Cocaine Use Disorder | Cheron J et al. | — | 2022 | — |
| Influence of Clinical Markers of Dopaminergic Behaviors on Depressive Symptoms During Withdrawal in Cocaine Users. | Cabé J et al. | — | 2021 | → |
| Substance-Induced Psychoses: An Updated Literature Review. | Fiorentini A et al. | — | 2021 | → |
| Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances. | Vorspan F et al. | — | 2020 | → |
| Accelerated Intermittent Theta-Burst Stimulation as a Treatment for Cocaine Use Disorder: A Proof-of-Concept Study. | Steele VR et al. | — | 2019 | → |
| Relevance of treated cocaine users' retrospective memory of first cocaine use. | Karsinti E et al. | — | 2018 | → |
| Higher severity of cocaine addiction is associated with tactile and somatic hallucinations. | Roncero C et al. | — | 2017 | → |
| Can symptoms help in differential diagnosis between substance-induced vs independent psychosis in adults with a lifetime diagnosis of cocaine use disorder? | Vergara-Moragues E et al. | — | 2016 | → |
| Differential effects of sex on substance use between first episode psychosis patients and healthy people. | Núñez C et al. | — | 2016 | → |
| Childhood trauma are not associated with the intensity of transient cocaine induced psychotic symptoms. | Karsinti E et al. | — | 2015 | → |
| Self-reported cue-induced physical symptoms of craving as an indicator of cocaine dependence. | Vorspan F et al. | — | 2015 | → |
| An international perspective and review of cocaine-induced psychosis: a call to action. | Roncero C et al. | — | 2014 | → |
| Clinical differences between cocaine-induced psychotic disorder and psychotic symptoms in cocaine-dependent patients. | Roncero C et al. | — | 2014 | → |
| Cocaine-induced psychotic disorders: presentation, mechanism, and management. | Tang Y et al. | — | 2014 | → |
| Cocaine-induced psychotic symptoms in clinical setting. | Vergara-Moragues E et al. | — | 2014 | → |
| Curious cases: Altered dose-response relationships in addiction genetics. | Uhl GR et al. | — | 2014 | → |
| Early cannabis use is associated with severity of Cocaine-Induced Psychosis among cocaine smokers in Martinique, French West Indies. | Trape S et al. | — | 2014 | → |
| Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. | Gelernter J et al. | — | 2014 | → |
| Cocaine-induced psychosis and impulsivity in cocaine-dependent patients. | Roncero C et al. | — | 2013 | → |
| Risk factors for cocaine-induced psychosis in cocaine-dependent patients. | Roncero C et al. | — | 2013 | → |
| [Addiction to cocaine and other stimulants]. | Lacoste J et al. | — | 2012 | → |
| Cocaine-induced psychotic symptoms in French cocaine addicts. | Vorspan F et al. | — | 2012 | → |
| Neuropsychological effects associated with recreational cocaine use. | Soar K et al. | — | 2012 | → |
| Psychiatric comorbidity in cocaine users treated in therapeutic community: substance-induced versus independent disorders. | Vergara-Moragues E et al. | — | 2012 | → |
| Prospective assessment of transient cocaine-induced psychotic symptoms in a clinical setting. | Vorspan F et al. | — | 2011 | → |
| Adolescent cannabis use increases risk for cocaine-induced paranoia. | Kalayasiri R et al. | — | 2010 | → |
| Could the inter-individual variability in cocaine-induced psychotic effects influence the development of cocaine addiction? Towards a new pharmacogenetic approach to addictions. | Brousse G et al. | — | 2010 | → |
| Methamphetamine and paranoia: the methamphetamine experience questionnaire. | Leamon MH et al. | — | 2010 | → |
| Temporal relationship of first-episode non-affective psychosis with cannabis use: a clinical verification of an epidemiological hypothesis. | Barrigón ML et al. | — | 2010 | → |
| Association of variants in MANEA with cocaine-related behaviors. | Farrer LA et al. | — | 2009 | → |
| Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia. | Fortuyn HA et al. | — | 2009 | → |
| Superstitious conditioning as a model of delusion formation following chronic but not acute ketamine in humans. | Freeman TP et al. | — | 2009 | → |
| Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP). | Tang YL et al. | — | 2009 | → |
| The validity of cocaine dependence subtypes. | Kranzler HR et al. | — | 2008 | → |
| Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects. | Tang YL et al. | — | 2007 | → |
| Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration. | Kalayasiri R et al. | — | 2007 | → |
| Novel research translates to clinical cases of schizophrenic and cocaine psychosis. | Nunes JV et al. | — | 2007 | → |
| Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs. | Kalayasiri R et al. | — | 2006 | → |
| Self-reported paranoia during laboratory "binge" cocaine self-administration in humans. | Kalayasiri R et al. | — | 2006 | → |