The genetics of quantitative traits: challenges and prospects.
paper
Cited
Public
Unavailable
- Authors
- Mackay, Trudy F C; Stone, Eric A; Ayroles, Julien F
- Year
- 2009
- Journal
- Nature reviews. Genetics
- PMID
- 19584810
- DOI
- 10.1038/nrg2612
A major challenge in current biology is to understand the genetic basis of variation for quantitative traits. We review the principles of quantitative trait locus mapping and summarize insights about the genetic architecture of quantitative traits that have been obtained over the past decades. We are currently in the midst of a genomic revolution, which enables us to incorporate genetic variation in transcript abundance and other intermediate molecular phenotypes into a quantitative trait locus mapping framework. This systems genetics approach enables us to understand the biology inside the 'black box' that lies between genotype and phenotype in terms of causal networks of interacting genes.
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| Genetic dissection of thousand-seed weight and fine mapping of cqSW.A03-2 via linkage and association analysis in rapeseed (Brassica napus L.). | Wang H et al. | — | 2020 | → |
| Genetic mapping using a wheat multi-founder population reveals a locus on chromosome 2A controlling resistance to both leaf and glume blotch caused by the necrotrophic fungal pathogen Parastagonospora nodorum. | Lin M et al. | — | 2020 | → |
| Genome wide identification of QTL associated with yield and yield components in two popular wheat cultivars TAM 111 and TAM 112. | Yang Y et al. | — | 2020 | → |
| Genomic architecture of gapeworm resistance in a natural bird population. | Ruiz-López MJ | — | 2020 | → |
| Identification of Novel Genomic Regions and Superior Alleles Associated with Zn Accumulation in Wheat Using a Genome-Wide Association Analysis Method. | Zhou Z et al. | — | 2020 | → |
| Leveraging Multiple Layers of Data To Predict <i>Drosophila</i> Complex Traits. | Morgante F et al. | — | 2020 | → |
| Life-History Evolution and the Genetics of Fitness Components in <i>Drosophila melanogaster</i>. | Flatt T | — | 2020 | → |
| Linkage mapping and genome-wide association study reveals conservative QTL and candidate genes for Fusarium rot resistance in maize. | Wu Y et al. | — | 2020 | → |
| Marker-assisted selection of <i>qMrdd8</i> to improve maize resistance to rough dwarf disease. | Xu Z et al. | — | 2020 | → |
| Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans. | Evans KS et al. | — | 2020 | → |
| Photosynthetic Metabolism under Stressful Growth Conditions as a Bases for Crop Breeding and Yield Improvement. | Morales F et al. | — | 2020 | → |
| Physical topography is associated with human personality. | Götz FM et al. | — | 2020 | → |
| Plasticity-led evolution: A survey of developmental mechanisms and empirical tests. | Levis NA et al. | — | 2020 | → |
| QTL.gCIMapping.GUI v2.0: An R software for detecting small-effect and linked QTLs for quantitative traits in bi-parental segregation populations. | Zhang YW et al. | — | 2020 | → |
| Quantitative trait loci involved in the reproductive success of a parasitoid wasp. | Benoist R et al. | — | 2020 | → |
| Quantitative Trait Loci (QTL) Mapping. | Powder KE | — | 2020 | → |
| Systematic identification of <i>cis</i>-regulatory variants that cause gene expression differences in a yeast cross. | Renganaath K et al. | — | 2020 | → |
| The Earth BioGenome project: opportunities and challenges for plant genomics and conservation. | Exposito-Alonso M et al. | — | 2020 | → |
| The Effects of Quantitative Trait Architecture on Detection Power in Short-Term Artificial Selection Experiments. | Lou RN et al. | — | 2020 | → |
| The genetic basis of animal behavioural diversity in natural populations. | Bubac CM et al. | — | 2020 | → |
| A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila. | Durmaz E et al. | — | 2019 | → |
| A Genome-Wide Association Study Revealed Key SNPs/Genes Associated With Salinity Stress Tolerance In Upland Cotton. | Yasir M et al. | — | 2019 | → |
| A large nested association mapping population for breeding and quantitative trait locus mapping in Ethiopian durum wheat. | Kidane YG et al. | — | 2019 | → |
| A multi-parent recombinant inbred line population of C. elegans allows identification of novel QTLs for complex life history traits. | Snoek BL et al. | — | 2019 | → |
| An efficient multi-locus mixed model framework for the detection of small and linked QTLs in F2. | Wen YJ et al. | — | 2019 | → |
| Association mapping of ectomycorrhizal traits in loblolly pine (Pinus taeda L.). | Piculell BJ et al. | — | 2019 | → |
| A unified DNA sequence and non-DNA sequence mapping model of complex traits. | Zeng Y et al. | — | 2019 | → |
| Changes throughout a Genetic Network Mask the Contribution of Hox Gene Evolution. | Liu Y et al. | — | 2019 | → |
| Co-inheritance of sea age at maturity and iteroparity in the Atlantic salmon vgll3 genomic region. | Aykanat T et al. | — | 2019 | → |
| Construction of a High-Density Linkage Map and QTL Fine Mapping for Growth- and Sex-Related Traits in Channel Catfish (<i>Ictalurus punctatus</i>). | Zhang S et al. | — | 2019 | → |
| Contribution of recent technological advances to future resistance breeding. | Sánchez-Martín J et al. | — | 2019 | → |
| Core set construction and association analysis of Pinus massoniana from Guangdong province in southern China using SLAF-seq. | Bai Q et al. | — | 2019 | → |
| Detecting the genetic basis of local adaptation in loblolly pine (<i>Pinus taeda</i> L.) using whole exome-wide genotyping and an integrative landscape genomics analysis approach. | Lu M et al. | — | 2019 | → |
| Dissecting a heterotic gene through GradedPool-Seq mapping informs a rice-improvement strategy. | Wang C et al. | — | 2019 | → |
| Dissection of Complex, Fitness-Related Traits in Multiple <i>Drosophila</i> Mapping Populations Offers Insight into the Genetic Control of Stress Resistance. | Everman ER et al. | — | 2019 | → |
| Evaluating Population Genomic Candidate Genes Underlying Flowering Time in Arabidopsis thaliana Using T-DNA Insertion Lines. | Chong VK et al. | — | 2019 | → |
| Extensive impact of low-frequency variants on the phenotypic landscape at population-scale. | Fournier T et al. | — | 2019 | → |
| Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk. | Burga A et al. | — | 2019 | → |
| Fine mapping and candidate gene analysis of qhkw5-3, a major QTL for kernel weight in maize. | Li W et al. | — | 2019 | → |
| First Genome-wide Association Analysis for Growth Traits in the Largest Coral Reef-Dwelling Bony Fishes, the Giant Grouper (Epinephelus lanceolatus). | Wu L et al. | — | 2019 | → |
| Functional models in genome-wide selection. | Moura EG et al. | — | 2019 | → |
| Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network. | Meng J et al. | — | 2019 | → |
| Genome-Wide Association Studies and Genomic Selection in Pearl Millet: Advances and Prospects. | Srivastava RK et al. | — | 2019 | → |
| Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. | Harbison ST et al. | — | 2019 | → |
| Genome-wide association study of maize plant architecture using F<sub>1</sub> populations. | Zhao Y et al. | — | 2019 | → |
| Identification of potential genomic regions and candidate genes for egg albumen quality by a genome-wide association study. | Qu L et al. | — | 2019 | → |
| Identification of QTL Related to ROS Formation under Hypoxia and Their Association with Waterlogging and Salt Tolerance in Barley. | Gill MB et al. | — | 2019 | → |
| <i>KAE1</i> Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in <i>Saccharomyces cerevisiae</i>. | Kessi-Pérez EI et al. | — | 2019 | → |
| Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains. | Kessi-Pérez EI et al. | — | 2019 | → |
| Insight into genetic regulation of miRNA in mouse brain. | Kordas G et al. | — | 2019 | → |
| Joint linkage and association mapping of complex traits in shrub willow (Salix purpurea L.). | Carlson CH et al. | — | 2019 | → |
| Key Genetic Parameters for Population Management. | Wellmann R et al. | — | 2019 | → |
| Optimizing the Power to Identify the Genetic Basis of Complex Traits with Evolve and Resequence Studies. | Vlachos C et al. | — | 2019 | → |
| Semiautomated Feature Extraction from RGB Images for Sorghum Panicle Architecture GWAS. | Zhou Y et al. | — | 2019 | → |
| Sex-Specific Co-expression Networks and Sex-Biased Gene Expression in the Salmonid Brook Charr <i>Salvelinus fontinalis</i>. | Sutherland BJG et al. | — | 2019 | → |
| Single-plant GWAS coupled with bulk segregant analysis allows rapid identification and corroboration of plant-height candidate SNPs. | Gyawali A et al. | — | 2019 | → |
| Standing genomic variation within coding and regulatory regions contributes to the adaptive capacity to climate in a foundation tree species. | Ahrens CW et al. | — | 2019 | → |
| Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. | Chakraborty M et al. | — | 2019 | → |
| Testing evolutionary predictions in wild mice. | Pelletier F | — | 2019 | → |
| The many faces of mathematical modelling in oncology. | Victori P et al. | — | 2019 | → |
| Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in <i>C. elegans</i>. | Bernstein MR et al. | — | 2019 | → |
| WhoGEM: an admixture-based prediction machine accurately predicts quantitative functional traits in plants. | Gentzbittel L et al. | — | 2019 | → |
| Accounting for heteroscedasticity and censoring in chromosome partitioning analyses. | Kemppainen P et al. | — | 2018 | → |
| A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus). | Feng X et al. | — | 2018 | → |
| A mapping framework of competition-cooperation QTLs that drive community dynamics. | Jiang L et al. | — | 2018 | → |
| A Methodological Assessment and Characterization of Genetically-Driven Variation in Three Human Phosphoproteomes. | Engelmann BW et al. | — | 2018 | → |
| A plant biodiversity effect resolved to a single chromosomal region. | Wuest SE et al. | — | 2018 | → |
| A plant biodiversity effect resolved to a single genetic locus | Wuest SE et al. | — | 2018 | — |
| A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila. | Mallard F et al. | — | 2018 | → |
| Assessing the Genetic Landscape of Animal Behavior. | York RA | — | 2018 | → |
| Beyond Genomic Prediction: Combining Different Types of <i>omics</i> Data Can Improve Prediction of Hybrid Performance in Maize. | Schrag TA et al. | — | 2018 | → |
| Candidate Genes for Aggressiveness in a Natural Fusarium culmorum Population Greatly Differ between Wheat and Rye Head Blight. | Castiblanco V et al. | — | 2018 | → |
| Characterization of Resistance to Cephus cinctus (Hymenoptera: Cephidae) in Barley Germplasm. | Varella AC et al. | — | 2018 | → |
| Contrasting results from GWAS and QTL mapping on wing length in great reed warblers. | Hansson B et al. | — | 2018 | → |
| Development and evaluation of high-density Axiom<sup>®</sup> CicerSNP Array for high-resolution genetic mapping and breeding applications in chickpea. | Roorkiwal M et al. | — | 2018 | → |
| Different Genomic Changes Underlie Adaptive Evolution in Populations of Contrasting History. | Seabra SG et al. | — | 2018 | → |
| Discovery and validation of genomic regions associated with resistance to maize lethal necrosis in four biparental populations. | Gowda M et al. | — | 2018 | → |
| Dissection and fine-mapping of two QTL for grain size linked in a 460-kb region on chromosome 1 of rice. | Dong Q et al. | — | 2018 | → |
| Effect of migration and environmental heterogeneity on the maintenance of quantitative genetic variation: a simulation study. | McDonald TK et al. | — | 2018 | → |
| Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans. | Gao AW et al. | — | 2018 | → |
| Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing. | Sharon E et al. | — | 2018 | → |
| Gene-gene and gene-environment interactions in complex traits in yeast. | Yadav A et al. | — | 2018 | → |
| Genetic architecture of traits associated with reproductive barriers in Silene: Coupling, sex chromosomes and variation. | Liu X et al. | — | 2018 | → |
| Genetic Basis of Body Color and Spotting Pattern in Redheaded Pine Sawfly Larvae (<i>Neodiprion lecontei</i>). | Linnen CR et al. | — | 2018 | → |
| Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells. | Lazzarano S et al. | — | 2018 | → |
| Genetics of dispersal. | Saastamoinen M et al. | — | 2018 | → |
| Genomic and environmental determinants and their interplay underlying phenotypic plasticity. | Li X et al. | — | 2018 | → |
| Heritability and genetic integration of anterior tooth crown variants in the South Carolina Gullah. | Stojanowski CM et al. | — | 2018 | → |
| Heritability of body size in the polar bears of Western Hudson Bay. | Malenfant RM et al. | — | 2018 | → |
| Hidden endemism, deep polyphyly, and repeated dispersal across the Isthmus of Tehuantepec: Diversification of the White-collared Seedeater complex (Thraupidae: <i>Sporophila torqueola</i>). | Mason NA et al. | — | 2018 | → |
| HT-eQTL: integrative expression quantitative trait loci analysis in a large number of human tissues. | Li G et al. | — | 2018 | → |
| Individual Variation in Social Behaviours of Male Lab-reared Prairie voles (Microtus ochrogaster) is Non-heritable and Weakly Associated with V1aR Density. | Vogel AR et al. | — | 2018 | → |
| Inferences of genetic architecture of bill morphology in house sparrow using a high-density SNP array point to a polygenic basis. | Lundregan SL et al. | — | 2018 | → |
| Insights Into Nicotinic Receptor Signaling in Nicotine Addiction: Implications for Prevention and Treatment. | Liu W et al. | — | 2018 | → |
| Intraspecific variation of residual heterozygosity and its utility for quantitative genetic studies in maize. | Liu N et al. | — | 2018 | → |
| Lead Modulates <i>trans-</i> and <i>cis-</i>Expression Quantitative Trait Loci (eQTLs) in <i>Drosophila melanogaster</i> Heads. | Qu W et al. | — | 2018 | → |
| Linkage disequilibrium clustering-based approach for association mapping with tightly linked genomewide data. | Li Z et al. | — | 2018 | → |
| Mapping Genetic Loci for Quantitative Traits of Golden Shell Color, Mineral Element Contents, and Growth-Related Traits in Pacific Oyster (Crassostrea gigas). | Song J et al. | — | 2018 | → |
| Mapping of quantitative trait loci for temporal growth and age at maturity in coho salmon: Evidence for genotype-by-sex interactions. | Kodama M et al. | — | 2018 | → |
| Mitonuclear epistasis, genotype-by-environment interactions, and personalized genomics of complex traits in Drosophila. | Rand DM et al. | — | 2018 | → |
| 'Omic' technologies as a helpful tool in radioecological research. | Volkova PY et al. | — | 2018 | → |
| Phenomic Selection Is a Low-Cost and High-Throughput Method Based on Indirect Predictions: Proof of Concept on Wheat and Poplar. | Rincent R et al. | — | 2018 | → |
| Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis. | Reilly JP et al. | — | 2018 | → |
| Pleiotropic effects of regulatory variation in tan result in correlation of two pigmentation traits in Drosophila melanogaster. | Endler L et al. | — | 2018 | → |
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | Dick DM et al. | — | 2018 | → |
| Quantifying how constraints limit the diversity of viable routes to adaptation. | Yeaman S et al. | — | 2018 | → |
| Success and failure in replication of genotype-phenotype associations: How does replication help in understanding the genetic basis of phenotypic variation in outbred populations? | Schielzeth H et al. | — | 2018 | → |
| The Genotype-Phenotype Relationships in the Light of Natural Selection. | Chen H et al. | — | 2018 | → |
| The Sleep Inbred Panel, a Collection of Inbred <i>Drosophila melanogaster</i> with Extreme Long and Short Sleep Duration. | Serrano Negron YL et al. | — | 2018 | → |
| The State of "<i>Omics</i>" Research for Farmed Penaeids: Advances in Research and Impediments to Industry Utilization. | Guppy JL et al. | — | 2018 | → |
| Unraveling lipid metabolism in maize with time-resolved multi-omics data. | de Abreu E Lima F et al. | — | 2018 | → |
| Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism. | Lusk R et al. | — | 2018 | → |
| Vitamin C Content in Fruits: Biosynthesis and Regulation. | Fenech M et al. | — | 2018 | → |
| What genomic data can reveal about eco-evolutionary dynamics. | Rudman SM et al. | — | 2018 | → |
| A Bivariate Hypothesis Testing Approach for Mapping the Trait-Influential Gene. | Saunders G et al. | — | 2017 | → |
| A Guide to Genome-Wide Association Mapping in Plants. | Burghardt LT et al. | — | 2017 | → |
| A High-Density Genetic Linkage Map and QTL Fine Mapping for Body Weight in Crucian Carp (<i>Carassius auratus</i>) Using 2b-RAD Sequencing. | Liu H et al. | — | 2017 | → |
| Association mapping analysis of fiber yield and quality traits in Upland cotton (Gossypium hirsutum L.). | Ademe MS et al. | — | 2017 | → |
| Association mapping of morphological traits in wild and captive zebra finches: reliable within, but not between populations. | Knief U et al. | — | 2017 | → |
| Association Mapping Reveals Genetic Loci Associated with Important Agronomic Traits in <i>Lentinula edodes</i>, Shiitake Mushroom. | Li C et al. | — | 2017 | → |
| Candidate gene based association mapping in Fusarium culmorum for field quantitative pathogenicity and mycotoxin production in wheat. | Castiblanco V et al. | — | 2017 | → |
| Cattle genome-wide analysis reveals genetic signatures in trypanotolerant N'Dama. | Kim SJ et al. | — | 2017 | → |
| cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes. | Li MJ et al. | — | 2017 | → |
| Deciphering the genomic architecture of the stickleback brain with a novel multilocus gene-mapping approach. | Li Z et al. | — | 2017 | → |
| Discovering Condition-Specific Gene Co-Expression Patterns Using Gaussian Mixture Models: A Cancer Case Study. | Ficklin SP et al. | — | 2017 | → |
| Dissecting genetic architecture of startle response in Drosophila melanogaster using multi-omics information. | Xue A et al. | — | 2017 | → |
| Dissection of Insertion-Deletion Variants within Differentially Expressed Genes Involved in Wood Formation in <i>Populus</i>. | Gong C et al. | — | 2017 | → |
| Environment-Dependent Genotype-Phenotype Associations in Avian Breeding Time. | Gienapp P et al. | — | 2017 | → |
| Epistasis: Searching for Interacting Genetic Variants Using Crosses. | Ehrenreich IM | — | 2017 | → |
| Epistasis: Searching for Interacting Genetic Variants Using Crosses. | Ehrenreich IM | — | 2017 | → |
| Evolutionary genetics of host shifts in herbivorous insects: insights from the age of genomics. | Vertacnik KL et al. | — | 2017 | → |
| Evolutionary Transcriptomics and Proteomics: Insight into Plant Adaptation. | Voelckel C et al. | — | 2017 | → |
| Exploring and Harnessing Haplotype Diversity to Improve Yield Stability in Crops. | Qian L et al. | — | 2017 | → |
| Exploring genetic associations with ceRNA regulation in the human genome. | Li MJ et al. | — | 2017 | → |
| Fifteen years of quantitative trait loci studies in fish: challenges and future directions. | Ashton DT et al. | — | 2017 | → |
| Gene co-expression network connectivity is an important determinant of selective constraint. | Mähler N et al. | — | 2017 | → |
| Genetic Analysis of Complex Traits in <i>Saccharomyces cerevisiae</i>. | Ehrenreich IM et al. | — | 2017 | → |
| Genetic backgrounds and hidden trait complexity in natural populations. | Fournier T et al. | — | 2017 | → |
| Genetic Bases of Fungal White Rot Wood Decay Predicted by Phylogenomic Analysis of Correlated Gene-Phenotype Evolution. | Nagy LG et al. | — | 2017 | → |
| Genetic dissection of yield traits in super hybrid rice Xieyou9308 using both unconditional and conditional genome-wide association mapping. | Zhang Y et al. | — | 2017 | → |
| Genetic variations in sterol regulatory element binding protein cleavage-activating protein (SCAP) are associated with blood pressure in overweight/obese Chinese children. | Yang YD et al. | — | 2017 | → |
| Genome-wide association studies dissect the genetic networks underlying agronomical traits in soybean. | Fang C et al. | — | 2017 | → |
| Genome-wide Association Studies for Female Fertility Traits in Chinese and Nordic Holsteins. | Liu A et al. | — | 2017 | → |
| Genome-wide association study of outcrossing in cytoplasmic male sterile lines of rice. | Guo L et al. | — | 2017 | → |
| Genome-wide mapping and prediction suggests presence of local epistasis in a vast elite winter wheat populations adapted to Central Europe. | He S et al. | — | 2017 | → |
| Genomics of coloration in natural animal populations. | San-Jose LM et al. | — | 2017 | → |
| High-density genetic map and identification of QTLs for responses to temperature and salinity stresses in the model brown alga Ectocarpus. | Avia K et al. | — | 2017 | → |
| High-Density Genetic Map Construction and Gene Mapping of Basal Branching Habit and Flowers per Leaf Axil in Sesame. | Mei H et al. | — | 2017 | → |
| High-density genetic mapping identifies the genetic basis of a natural colony morphology mutant in the root rot pathogen Armillaria ostoyae. | Heinzelmann R et al. | — | 2017 | → |
| Incorporating pleiotropic quantitative trait loci in dissection of complex traits: seed yield in rapeseed as an example. | Luo Z et al. | — | 2017 | → |
| Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs. | Ballester M et al. | — | 2017 | → |
| Integrative Approaches for Studying Mitochondrial and Nuclear Genome Co-evolution in Oxidative Phosphorylation. | Sunnucks P et al. | — | 2017 | → |
| Model based heritability scores for high-throughput sequencing data. | Rudra P et al. | — | 2017 | → |
| Modeling of a negative feedback mechanism explains antagonistic pleiotropy in reproduction in domesticated Caenorhabditis elegans strains. | Large EE et al. | — | 2017 | → |
| Natural gene expression variation studies in yeast. | Thompson DA et al. | — | 2017 | → |
| Natural Variation and Genetics of Photoperiodism in Wyeomyia smithii. | Bradshaw WE et al. | — | 2017 | → |
| Omics-based hybrid prediction in maize. | Westhues M et al. | — | 2017 | → |
| QTL mapping and comparative genome analysis of agronomic traits including grain yield in winter rye. | Hackauf B et al. | — | 2017 | → |
| Quantitative trait loci from identification to exploitation for crop improvement. | Kumar J et al. | — | 2017 | → |
| Quantitative Trait Loci Mapping for Spike Characteristics in Hexaploid Wheat. | Zhou Y et al. | — | 2017 | → |
| Quantitative Trait Loci (QTL)-Guided Metabolic Engineering of a Complex Trait. | Maurer MJ et al. | — | 2017 | → |
| Reconstructing the Molecular Function of Genetic Variation in Regulatory Networks. | Wilentzik R et al. | — | 2017 | → |
| Regional Association Analysis of MetaQTLs Delineates Candidate Grain Size Genes in Rice. | Daware AV et al. | — | 2017 | → |
| Regulatory Architecture of Gene Expression Variation in the Threespine Stickleback Gasterosteus aculeatus. | Pritchard VL et al. | — | 2017 | → |
| Relating quantitative variation within a behavior to variation in transcription. | Benowitz KM et al. | — | 2017 | → |
| Resolving the Complex Genetic Basis of Phenotypic Variation and Variability of Cellular Growth. | Ziv N et al. | — | 2017 | → |
| Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. | Mitra I et al. | — | 2017 | → |
| Rice Flowering Locus T 1 plays an important role in heading date influencing yield traits in rice. | Zhu YJ et al. | — | 2017 | → |
| Sex Chromosome Evolution, Heterochiasmy, and Physiological QTL in the Salmonid Brook Charr <i>Salvelinus fontinalis</i>. | Sutherland BJG et al. | — | 2017 | → |
| Significant Synteny and Colocalization of Ecologically Relevant Quantitative Trait Loci Within and Across Species of Salmonid Fishes. | Jacobs A et al. | — | 2017 | → |
| Statistical Methods for Latent Class Quantitative Trait Loci Mapping. | Ye S et al. | — | 2017 | → |
| Systems Genetics as a Tool to Identify Master Genetic Regulators in Complex Disease. | Moreno-Moral A et al. | — | 2017 | → |
| The genetic architecture in Saccharomyces cerevisiae that contributes to variation in drug response to the antifungals benomyl and ketoconazole. | Roberts CA et al. | — | 2017 | → |
| The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae. | García-Ríos E et al. | — | 2017 | → |
| The Interactions between the Long Non-coding RNA NERDL and Its Target Gene Affect Wood Formation in <i>Populus tomentosa</i>. | Shi W et al. | — | 2017 | → |
| The transcriptional architecture of phenotypic dimorphism. | Mank JE | — | 2017 | → |
| Trait Correlations in the Genomics Era. | Saltz JB et al. | — | 2017 | → |
| Two Loci Contribute Epistastically to Heterospecific Pollen Rejection, a Postmating Isolating Barrier Between Species. | Hamlin JAP et al. | — | 2017 | → |
| Uncovering the Genetic Architecture of Seed Weight and Size in Intermediate Wheatgrass through Linkage and Association Mapping. | Zhang X et al. | — | 2017 | → |
| Validating Genome-Wide Association Candidates Controlling Quantitative Variation in Nodulation. | Curtin SJ et al. | — | 2017 | → |
| Water availability drives signatures of local adaptation in whitebark pine (Pinus albicaulis Engelm.) across fine spatial scales of the Lake Tahoe Basin, USA. | Lind BM et al. | — | 2017 | → |
| Whole genome sequencing of one complex pedigree illustrates challenges with genomic medicine. | Fang H et al. | — | 2017 | → |
| A MAGIC population-based genome-wide association study reveals functional association of GhRBB1_A07 gene with superior fiber quality in cotton. | Islam MS et al. | — | 2016 | → |
| A multi-marker association method for genome-wide association studies without the need for population structure correction. | Klasen JR et al. | — | 2016 | → |
| Autonomy and integration in complex parasite life cycles. | Benesh DP | — | 2016 | → |
| Buffering of Genetic Regulatory Networks in Drosophila melanogaster. | Fear JM et al. | — | 2016 | → |
| Cross-Study Comparison Reveals Common Genomic, Network, and Functional Signatures of Desiccation Resistance in Drosophila melanogaster. | Telonis-Scott M et al. | — | 2016 | → |
| Detecting Polygenic Evolution: Problems, Pitfalls, and Promises. | Wellenreuther M et al. | — | 2016 | → |
| Detection of Favorable QTL Alleles and Candidate Genes for Lint Percentage by GWAS in Chinese Upland Cotton. | Su J et al. | — | 2016 | → |
| Differential Regulation of Cryptic Genetic Variation Shapes the Genetic Interactome Underlying Complex Traits. | Yadav A et al. | — | 2016 | → |
| Dissection of genetic architecture of rice plant height and heading date by multiple-strategy-based association studies. | Zhou L et al. | — | 2016 | → |
| Dissection of the qTGW1.1 region into two tightly-linked minor QTLs having stable effects for grain weight in rice. | Zhang HW et al. | — | 2016 | → |
| E-Index for Differentiating Complex Dynamic Traits. | Qi J et al. | — | 2016 | → |
| Epistasis and Pleiotropy Affect the Modularity of the Genotype-Phenotype Map of Cross-Resistance in HIV-1. | Polster R et al. | — | 2016 | → |
| Exploring Genetic Diversity in Plants Using High-Throughput Sequencing Techniques. | Onda Y et al. | — | 2016 | → |
| Fine mapping QTL for resistance to VNN disease using a high-density linkage map in Asian seabass. | Liu P et al. | — | 2016 | → |
| From integrative genomics to systems genetics in the rat to link genotypes to phenotypes. | Moreno-Moral A et al. | — | 2016 | → |
| Functional Genomic Insights into Regulatory Mechanisms of High-Altitude Adaptation. | Storz JF et al. | — | 2016 | → |
| Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction. | Matsui T et al. | — | 2016 | → |
| Genes with a Combination of Over-Dominant and Epistatic Effects Underlie Heterosis in Growth of Saccharomyces cerevisiae at High Temperature. | Shapira R et al. | — | 2016 | → |
| Genetic architecture of growth traits in Populus revealed by integrated quantitative trait locus (QTL) analysis and association studies. | Du Q et al. | — | 2016 | → |
| Genetic architecture of the maize kernel row number revealed by combining QTL mapping using a high-density genetic map and bulked segregant RNA sequencing. | Liu C et al. | — | 2016 | → |
| Genetic architecture of wood properties based on association analysis and co-expression networks in white spruce. | Lamara M et al. | — | 2016 | → |
| Genetic assimilation: a review of its potential proximate causes and evolutionary consequences. | Ehrenreich IM et al. | — | 2016 | → |
| Genetic control of root growth: from genes to networks. | Slovak R et al. | — | 2016 | → |
| Genetic dissection of fruiting body-related traits using quantitative trait loci mapping in Lentinula edodes. | Gong WB et al. | — | 2016 | → |
| Genome-wide dissection of the maize ear genetic architecture using multiple populations. | Xiao Y et al. | — | 2016 | → |
| Genomics and Biochemistry of Saccharomyces cerevisiae Wine Yeast Strains. | Eldarov MA et al. | — | 2016 | → |
| Inclusion of Dominance Effects in the Multivariate GBLUP Model. | dos Santos JP et al. | — | 2016 | → |
| Investigating genomic and phenotypic parallelism between piscivorous and planktivorous lake trout (Salvelinus namaycush) ecotypes by means of RADseq and morphometrics analyses. | Bernatchez S et al. | — | 2016 | → |
| Modularity: genes, development and evolution. | Melo D et al. | — | 2016 | → |
| Multi-environment QTL analysis of grain morphology traits and fine mapping of a kernel-width QTL in Zheng58 × SK maize population. | Raihan MS et al. | — | 2016 | → |
| Multi-locus Genotypes Underlying Temperature Sensitivity in a Mutationally Induced Trait. | Lee JT et al. | — | 2016 | → |
| Natural variation in non-coding regions underlying phenotypic diversity in budding yeast. | Salinas F et al. | — | 2016 | → |
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| OGS2: genome re-annotation of the jewel wasp Nasonia vitripennis. | Rago A et al. | — | 2016 | → |
| Pleiotropy and the evolution of floral integration. | Smith SD | — | 2016 | → |
| POEM: Identifying Joint Additive Effects on Regulatory Circuits. | Botzman M et al. | — | 2016 | → |
| Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. | Okada H et al. | — | 2016 | → |
| Quantitative trait locus analysis of body shape divergence in nine-spined sticklebacks based on high-density SNP-panel. | Yang J et al. | — | 2016 | → |
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| The Genetics of Transcription Factor DNA Binding Variation. | Deplancke B et al. | — | 2016 | → |
| The Genome of the Self-Fertilizing Mangrove Rivulus Fish, Kryptolebias marmoratus: A Model for Studying Phenotypic Plasticity and Adaptations to Extreme Environments. | Kelley JL et al. | — | 2016 | → |
| The Hidden Complexity of Mendelian Traits across Natural Yeast Populations. | Hou J et al. | — | 2016 | → |
| The Molecular Basis of Human Brain Evolution. | Enard W | — | 2016 | → |
| The population genomics of rapid adaptation: disentangling signatures of selection and demography in white sands lizards. | Laurent S et al. | — | 2016 | → |
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| A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder. | Ashbrook DG et al. | — | 2015 | → |
| Adaptation in flower form: a comparative evodevo approach. | Specht CD et al. | — | 2015 | → |
| Alleles versus mutations: Understanding the evolution of genetic architecture requires a molecular perspective on allelic origins. | Remington DL | — | 2015 | → |
| A Major Locus Controls a Genital Shape Difference Involved in Reproductive Isolation Between Drosophila yakuba and Drosophila santomea. | Peluffo AE et al. | — | 2015 | → |
| Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae. | Reavey CT et al. | — | 2015 | → |
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| Comparative Genetics of Seed Size Traits in Divergent Cereal Lineages Represented by Sorghum (Panicoidae) and Rice (Oryzoidae). | Zhang D et al. | — | 2015 | → |
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| Evolution of Quantitative Traits under a Migration-Selection Balance: When Does Skew Matter? | Débarre F et al. | — | 2015 | → |
| Exome and transcriptome sequencing of Aedes aegypti identifies a locus that confers resistance to Brugia malayi and alters the immune response. | Juneja P et al. | — | 2015 | → |
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| Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster. | Dembeck LM et al. | — | 2015 | → |
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| Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence. | Bou Sleiman MS et al. | — | 2015 | → |
| Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays. | Dell'Acqua M et al. | — | 2015 | → |
| Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster. | Appel M et al. | — | 2015 | → |
| Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array. | Tsai HY et al. | — | 2015 | → |
| Genome-wide association mapping in a wild avian population identifies a link between genetic and phenotypic variation in a life-history trait. | Husby A et al. | — | 2015 | → |
| Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize. | Ding J et al. | — | 2015 | → |
| Genome-wide association studies for feed intake and efficiency in two laying periods of chickens. | Yuan J et al. | — | 2015 | → |
| Genome-wide association study (GWAS) for growth rate and age at sexual maturation in Atlantic salmon (Salmo salar). | Gutierrez AP et al. | — | 2015 | → |
| High-resolution genetic maps of Eucalyptus improve Eucalyptus grandis genome assembly. | Bartholomé J et al. | — | 2015 | → |
| High-resolution mapping of a major effect QTL from wild tomato Solanum habrochaites that influences water relations under root chilling. | Arms EM et al. | — | 2015 | → |
| Identification of Promising Mutants Associated with Egg Production Traits Revealed by Genome-Wide Association Study. | Yuan J et al. | — | 2015 | → |
| Investigation of Functional Genes at Homologous Loci Identified Based on Genome-wide Association Studies of Blood Lipids via High-fat Diet Intervention in Rats using an in vivo Approach. | Akiyama K et al. | — | 2015 | → |
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| Low but significant genetic differentiation underlies biologically meaningful phenotypic divergence in a large Atlantic salmon population. | Aykanat T et al. | — | 2015 | → |
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| Multiple-Line Inference of Selection on Quantitative Traits. | Riedel N et al. | — | 2015 | → |
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| Replicated analysis of the genetic architecture of quantitative traits in two wild great tit populations. | Santure AW et al. | — | 2015 | → |
| Systems Biology for Smart Crops and Agricultural Innovation: Filling the Gaps between Genotype and Phenotype for Complex Traits Linked with Robust Agricultural Productivity and Sustainability. | Kumar A et al. | — | 2015 | → |
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| The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. | Friedman J et al. | — | 2015 | → |
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| The genetics of feed conversion efficiency traits in a commercial broiler line. | Reyer H et al. | — | 2015 | → |
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| Verification of SNPs Associated with Growth Traits in Two Populations of Farmed Atlantic Salmon. | Tsai HY et al. | — | 2015 | → |
| A candidate gene association study for growth performance in an improved giant freshwater prawn (Macrobrachium rosenbergii ) culture line. | Jung H et al. | — | 2014 | → |
| A first step toward the development of a barley NAM population and its utilization to detect QTLs conferring leaf rust seedling resistance. | Schnaithmann F et al. | — | 2014 | → |
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| Association mapping in crop plants: opportunities and challenges. | Gupta PK et al. | — | 2014 | → |
| Association mapping of stem rust race TTKSK resistance in US barley breeding germplasm. | Zhou H et al. | — | 2014 | → |
| Association studies including genotype by environment interactions: prospects and limits. | Saïdou AA et al. | — | 2014 | → |
| Automated, quantitative cognitive/behavioral screening of mice: for genetics, pharmacology, animal cognition and undergraduate instruction. | Gallistel CR et al. | — | 2014 | → |
| Behavioral effects of social challenges and genomic mechanisms of social priming: What's testosterone got to do with it? | Rosvall KA et al. | — | 2014 | → |
| Cell wall-related proteins of unknown function: missing links in plant cell wall development. | Mewalal R et al. | — | 2014 | → |
| Challenges and prospects in genome-wide quantitative trait loci mapping of standing genetic variation in natural populations. | Schielzeth H et al. | — | 2014 | → |
| Climate change, adaptation, and phenotypic plasticity: the problem and the evidence. | Merilä J et al. | — | 2014 | → |
| Climate change in the oceans: evolutionary versus phenotypically plastic responses of marine animals and plants. | Reusch TB | — | 2014 | → |
| Combining linkage and association mapping identifies RECEPTOR-LIKE PROTEIN KINASE1 as an essential Arabidopsis shoot regeneration gene. | Motte H et al. | — | 2014 | → |
| Common genetic variants modulate pathogen-sensing responses in human dendritic cells. | Lee MN et al. | — | 2014 | → |
| Current advances in systems and integrative biology. | Robinson SW et al. | — | 2014 | → |
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| Expression quantitative trait analyses to identify causal genetic variants for type 2 diabetes susceptibility. | Das SK et al. | — | 2014 | → |
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| Genome-wide association implicates numerous genes underlying ecological trait variation in natural populations of Populus trichocarpa. | McKown AD et al. | — | 2014 | → |
| Genome-wide patterns of polymorphism in an inbred line of the African malaria mosquito Anopheles gambiae. | Turissini DA et al. | — | 2014 | → |
| Genotype×environment interaction QTL mapping in plants: lessons from Arabidopsis. | El-Soda M et al. | — | 2014 | → |
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| Highly polygenic variation in environmental perception determines dauer larvae formation in growing populations of Caenorhabditis elegans. | Green JW et al. | — | 2014 | → |
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| Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants. | Wang S et al. | — | 2014 | → |
| Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. | Ashbrook DG et al. | — | 2014 | → |
| Multiple QTL for horticultural traits and quantitative resistance to Phytophthora infestans linked on Solanum habrochaites chromosome 11. | Haggard JE et al. | — | 2014 | → |
| Natural selection: it's a many-small world after all. | Roesti M et al. | — | 2014 | → |
| Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. | Huang W et al. | — | 2014 | → |
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| QTL mapping of freezing tolerance: links to fitness and adaptive trade-offs. | Oakley CG et al. | — | 2014 | → |
| Quantitative trait loci × environment interactions for plant morphology vary over ontogeny in Brassica rapa. | Dechaine JM et al. | — | 2014 | → |
| Recent coselection in human populations revealed by protein-protein interaction network. | Qian W et al. | — | 2014 | → |
| Single nucleotide polymorphism and haplotype effects associated with somatic cell score in German Holstein cattle. | Abdel-Shafy H et al. | — | 2014 | → |
| Systems mapping: how to map genes for biomass allocation toward an ideotype. | Bo W et al. | — | 2014 | → |
| The age related markers lipofuscin and apoptosis show different genetic architecture by QTL mapping in short-lived Nothobranchius fish. | Ng'oma E et al. | — | 2014 | → |
| The evolutionary genomics of cichlid fishes: explosive speciation and adaptation in the postgenomic era. | Henning F et al. | — | 2014 | → |
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| The genotype-phenotype map of yeast complex traits: basic parameters and the role of natural selection. | Ho WC et al. | — | 2014 | → |
| The power to detect quantitative trait loci using resequenced, experimentally evolved populations of diploid, sexual organisms. | Baldwin-Brown JG et al. | — | 2014 | → |
| Towards a comprehensive picture of the genetic landscape of complex traits. | Wang Z et al. | — | 2014 | → |
| Using genomics to characterize evolutionary potential for conservation of wild populations. | Harrisson KA et al. | — | 2014 | → |
| A candidate gene based approach validates Md-PG1 as the main responsible for a QTL impacting fruit texture in apple (Malus x domestica Borkh). | Longhi S et al. | — | 2013 | → |
| Additive genetic architecture underlying a rapidly evolving sexual signaling phenotype in the Hawaiian cricket genus Laupala. | Ellison CK et al. | — | 2013 | → |
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| An overview of natural variation studies in the Arabidopsis thaliana circadian clock. | Anwer MU et al. | — | 2013 | → |
| Complex genetic effects on early vegetative development shape resource allocation differences between Arabidopsis lyrata populations. | Remington DL et al. | — | 2013 | → |
| Complex inheritance of melanoma and pigmentation of coat and skin in Grey horses. | Curik I et al. | — | 2013 | → |
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| Evidence for adaptive phenotypic differentiation in Baltic Sea sticklebacks. | Defaveri J et al. | — | 2013 | → |
| Favorable QTL alleles for yield and its components identified by association mapping in Chinese Upland cotton cultivars. | Mei H et al. | — | 2013 | → |
| Finding the sources of missing heritability in a yeast cross. | Bloom JS et al. | — | 2013 | → |
| Genetic and neural modularity underlie the evolution of schooling behavior in threespine sticklebacks. | Greenwood AK et al. | — | 2013 | → |
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| Genetic map construction and quantitative trait locus (QTL) detection of growth-related traits in Litopenaeus vannamei for selective breeding applications. | Andriantahina F et al. | — | 2013 | → |
| Genome-wide association mapping for wood characteristics in Populus identifies an array of candidate single nucleotide polymorphisms. | Porth I et al. | — | 2013 | → |
| Genome-wide association study of sleep in Drosophila melanogaster. | Harbison ST et al. | — | 2013 | → |
| Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver. | Schröder A et al. | — | 2013 | → |
| Haemonchus contortus as a paradigm and model to study anthelmintic drug resistance. | Gilleard JS | — | 2013 | → |
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| Linkage relationships among multiple QTL for horticultural traits and late blight (P. infestans) resistance on chromosome 5 introgressed from wild tomato Solanum habrochaites. | Haggard JE et al. | — | 2013 | → |
| Nature's inordinate fondness for metabolic enzymes: why metabolic enzyme loci are so frequently targets of selection. | Marden JH | — | 2013 | → |
| Network analysis reveals the relationship among wood properties, gene expression levels and genotypes of natural Populus trichocarpa accessions. | Porth I et al. | — | 2013 | → |
| New components of Drosophila leg development identified through genome wide association studies. | Grubbs N et al. | — | 2013 | → |
| Nine-spined stickleback (Pungitius pungitius): an emerging model for evolutionary biology research. | Merilä J | — | 2013 | → |
| Parsing parallel evolution: ecological divergence and differential gene expression in the adaptive radiations of thick-lipped Midas cichlid fishes from Nicaragua. | Manousaki T et al. | — | 2013 | → |
| Partitioning of genetic variation across the genome using multimarker methods in a wild bird population. | Robinson MR et al. | — | 2013 | → |
| Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals. | van Vliet-Ostaptchouk JV et al. | — | 2013 | → |
| Precision phenotyping of biomass accumulation in triticale reveals temporal genetic patterns of regulation. | Busemeyer L et al. | — | 2013 | → |
| Predicting complex traits using a diffusion kernel on genetic markers with an application to dairy cattle and wheat data. | Morota G et al. | — | 2013 | → |
| Q(ST)-F(ST) comparisons: evolutionary and ecological insights from genomic heterogeneity. | Leinonen T et al. | — | 2013 | → |
| Quantitative trait loci associated with tipburn, heat stress-induced physiological disorders, and maturity traits in crisphead lettuce. | Jenni S et al. | — | 2013 | → |
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| Random forests on Hadoop for genome-wide association studies of multivariate neuroimaging phenotypes. | Wang Y et al. | — | 2013 | → |
| Signatures of natural selection on genetic variants affecting complex human traits. | Zhang G et al. | — | 2013 | → |
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| The causes of variation in learning and behavior: why individual differences matter. | Sauce B et al. | — | 2013 | → |
| The easy road to genome-wide medium density SNP screening in a non-model species: development and application of a 10 K SNP-chip for the house sparrow (Passer domesticus). | Hagen IJ et al. | — | 2013 | → |
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| The genetic architecture of reproductive isolation during speciation-with-gene-flow in lake whitefish species pairs assessed by RAD sequencing. | Gagnaire PA et al. | — | 2013 | → |
| The strength of genetic interactions scales weakly with mutational effects. | Velenich A et al. | — | 2013 | → |
| Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes. | Chow CY et al. | — | 2013 | → |
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| Cellulose factories: advancing bioenergy production from forest trees. | Mizrachi E et al. | — | 2012 | → |
| Coding Gene SNP Mapping Reveals QTL Linked to Growth and Stress Response in Brook Charr (Salvelinus fontinalis). | Sauvage C et al. | — | 2012 | → |
| Complex genetics controls natural variation among seed quality phenotypes in a recombinant inbred population of an interspecific cross between Solanum lycopersicum × Solanum pimpinellifolium. | Kazmi RH et al. | — | 2012 | → |
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| Divergent natural selection with gene flow along major environmental gradients in Amazonia: insights from genome scans, population genetics and phylogeography of the characin fish Triportheus albus. | Cooke GM et al. | — | 2012 | → |
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| Genetic architecture of highly complex chemical resistance traits across four yeast strains. | Ehrenreich IM et al. | — | 2012 | → |
| Genetic mapping of quantitative trait loci for disease-related phenotypes. | Devoto M et al. | — | 2012 | → |
| Genetic polymorphism in dopamine receptor D4 is associated with early body condition in a large population of greater flamingos, Phoenicopterus roseus. | Gillingham MA et al. | — | 2012 | → |
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| Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice. | Crowley JJ et al. | — | 2012 | → |
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| Genomic variation and its impact on gene expression in Drosophila melanogaster. | Massouras A et al. | — | 2012 | → |
| Identifying loci influencing 1,000-kernel weight in wheat by microsatellite screening for evidence of selection during breeding. | Wang L et al. | — | 2012 | → |
| Lessons from eQTL mapping studies: non-coding regions and their role behind natural phenotypic variation in plants. | Cubillos FA et al. | — | 2012 | → |
| Localizing F(ST) outliers on a QTL map reveals evidence for large genomic regions of reduced gene exchange during speciation-with-gene-flow. | Via S et al. | — | 2012 | → |
| Mapping QTL for agronomic traits in breeding populations. | Würschum T | — | 2012 | → |
| Natural variation in GA1 associates with floral morphology in Arabidopsis thaliana. | Brock MT et al. | — | 2012 | → |
| NGS technologies for analyzing germplasm diversity in genebanks. | Kilian B et al. | — | 2012 | → |
| Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster. | Jumbo-Lucioni P et al. | — | 2012 | → |
| Patterns of cis regulatory variation in diverse human populations. | Stranger BE et al. | — | 2012 | → |
| Phenotypic plasticity of the Drosophila transcriptome. | Zhou S et al. | — | 2012 | → |
| Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples. | Mullen MP et al. | — | 2012 | → |
| QTL detection power of multi-parental RIL populations in Arabidopsis thaliana. | Klasen JR et al. | — | 2012 | → |
| Quantitative genetics in the genomics era. | Hill WG | — | 2012 | → |
| Rare and common variants: twenty arguments. | Gibson G | — | 2012 | → |
| Recent approaches to the prioritization of candidate disease genes. | Doncheva NT et al. | — | 2012 | → |
| Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner. | Stoltenberg SF et al. | — | 2012 | → |
| Single nucleotide polymorphisms in the bovine genome are associated with the number of oocytes collected during ovum pick up. | Santos-Biase WK et al. | — | 2012 | → |
| Statistical method for mapping QTLs for complex traits based on two backcross populations. | Zhihong Z et al. | — | 2012 | → |
| Subcongenic analysis of tabw2 obesity QTL on mouse chromosome 6. | Stewart TP et al. | — | 2012 | → |
| Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9. | Carroll SF et al. | — | 2012 | → |
| Systems biology of kidney diseases. | He JC et al. | — | 2012 | → |
| Systems genetics of the nuclear factor-κB signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging. | Diego VP et al. | — | 2012 | → |
| The Drosophila melanogaster Genetic Reference Panel. | Mackay TF et al. | — | 2012 | → |
| The fundamentals of flying: simple and inexpensive strategies for employing Drosophila genetics in neuroscience teaching laboratories. | Pulver SR et al. | — | 2012 | → |
| The genetic architecture of a complex ecological trait: host plant use in the specialist moth, Heliothis subflexa. | Oppenheim SJ et al. | — | 2012 | → |
| The genetic basis of natural variation in oenological traits in Saccharomyces cerevisiae. | Salinas F et al. | — | 2012 | → |
| The genetic differentiation at quantitative trait loci under local adaptation. | Le Corre V et al. | — | 2012 | → |
| The genotype-phenotype maps of systems biology and quantitative genetics: distinct and complementary. | Landry CR et al. | — | 2012 | → |
| The QTN program and the alleles that matter for evolution: all that's gold does not glitter. | Rockman MV | — | 2012 | → |
| Towards multiscale plant models: integrating cellular networks. | Baldazzi V et al. | — | 2012 | → |
| Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. | Ober U et al. | — | 2012 | → |
| Adaptation in the age of ecological genomics: insights from parallelism and convergence. | Elmer KR et al. | — | 2011 | → |
| A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature germination locus Htg6.1 in lettuce (Lactuca sp.). | Argyris J et al. | — | 2011 | → |
| A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity. | Brown WR et al. | — | 2011 | → |
| A QTL on chromosome 10 modulates cone photoreceptor number in the mouse retina. | Whitney IE et al. | — | 2011 | → |
| Assessing the complex architecture of polygenic traits in diverged yeast populations. | Cubillos FA et al. | — | 2011 | → |
| Association genetics of carbon isotope discrimination, height and foliar nitrogen in a natural population of Pinus taeda L. | Cumbie WP et al. | — | 2011 | → |
| Association genetics of complex traits in plants. | Ingvarsson PK et al. | — | 2011 | → |
| Catecholamine receptor polymorphisms affect decision-making in C. elegans. | Bendesky A et al. | — | 2011 | → |
| Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer. | Hansen TF et al. | — | 2011 | → |
| Community genetics: what have we accomplished and where should we be going? | Hersch-Green EI et al. | — | 2011 | → |
| Complex genetic architecture of Drosophila aggressive behavior. | Zwarts L et al. | — | 2011 | → |
| Crop genomics: advances and applications. | Morrell PL et al. | — | 2011 | → |
| Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis. | Yazbek SN et al. | — | 2011 | → |
| Disrupted post-transcriptional regulation of the cystic fibrosis transmembrane conductance regulator (CFTR) by a 5'UTR mutation is associated with a CFTR-related disease. | Lukowski SW et al. | — | 2011 | → |
| Dissecting genetic networks underlying complex phenotypes: the theoretical framework. | Zhang F et al. | — | 2011 | → |
| Do large effect QTL fractionate? A case study at the maize domestication QTL teosinte branched1. | Studer AJ et al. | — | 2011 | → |
| Ecological genetics and genomics of plant defenses: Evidence and approaches. | Anderson JT et al. | — | 2011 | → |
| Enhancer trapping in plants. | Chudalayandi S | — | 2011 | → |
| Epistasis: the key to understanding immunological disease? | Mitchison NA et al. | — | 2011 | → |
| Evolution of competitive ability: an adaptation speed vs. accuracy tradeoff rooted in gene network size. | Malcom JW | — | 2011 | → |
| Expression level polymorphisms: heritable traits shaping natural variation. | Delker C et al. | — | 2011 | → |
| Expression profiling without genome sequence information in a non-model species, Pandalid shrimp (Pandalus latirostris), by next-generation sequencing. | Kawahara-Miki R et al. | — | 2011 | → |
| Extraordinary conservation, gene loss, and positive selection in the evolution of an ancient neurotoxin. | Murray SA et al. | — | 2011 | → |
| From sequence to function: Insights from natural variation in budding yeasts. | Nieduszynski CA et al. | — | 2011 | → |
| Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks. | Ayroles JF et al. | — | 2011 | → |
| Genetic architecture of body weight, condition factor and age of sexual maturation in Icelandic Arctic charr (Salvelinus alpinus). | Küttner E et al. | — | 2011 | → |
| Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations. | Lawson HA et al. | — | 2011 | → |
| Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? | Casto AM et al. | — | 2011 | → |
| Global analysis of genes involved in freshwater adaptation in threespine sticklebacks (Gasterosteus aculeatus). | DeFaveri J et al. | — | 2011 | → |
| Humanized Foxp2 specifically affects cortico-basal ganglia circuits. | Reimers-Kipping S et al. | — | 2011 | → |
| Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India. | Alter A et al. | — | 2011 | → |
| Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight. | Mollah MB et al. | — | 2011 | → |
| Is life law-like? | Weiss KM et al. | — | 2011 | → |
| Joint genetic analysis of gene expression data with inferred cellular phenotypes. | Parts L et al. | — | 2011 | → |
| Microarray evidences the role of pathologic adipose tissue in insulin resistance and their clinical implications. | Mathur SK et al. | — | 2011 | → |
| Molecular genetic approaches for identifying the basis of variation in resistance to tick infestation in cattle. | Porto Neto LR et al. | — | 2011 | → |
| Molecular mechanisms of epistasis within and between genes. | Lehner B | — | 2011 | → |
| Molecular spandrels: tests of adaptation at the genetic level. | Barrett RD et al. | — | 2011 | → |
| Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening. | Gorini G et al. | — | 2011 | → |
| Natural genetic variation in plant photosynthesis. | Flood PJ et al. | — | 2011 | → |
| Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility. | Quigley DA et al. | — | 2011 | → |
| Next-generation mapping of complex traits with phenotype-based selection and introgression. | Earley EJ et al. | — | 2011 | → |
| Perspectives on genome-wide multi-stage family-based association studies. | Van Steen K | — | 2011 | → |
| Phenotype prediction by integrative network analysis of SNP and gene expression microarrays. | Chang HH et al. | — | 2011 | → |
| Progress and promise of genome-wide association studies for human complex trait genetics. | Stranger BE et al. | — | 2011 | → |
| Proteomic and metabolomic profiling of a trait anxiety mouse model implicate affected pathways. | Zhang Y et al. | — | 2011 | → |
| Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis. | Avagyan S et al. | — | 2011 | → |
| Smaller gene networks permit longer persistence in fast-changing environments. | Malcom JW | — | 2011 | → |
| Stressing zebrafish for behavioral genetics. | Clark KJ et al. | — | 2011 | → |
| Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems. | Wu R et al. | — | 2011 | → |
| Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection. | Albert FW et al. | — | 2011 | → |
| The clinical implications of mouse models of enhanced anxiety. | Sartori SB et al. | — | 2011 | → |
| The future of model organisms in human disease research. | Aitman TJ et al. | — | 2011 | → |
| The importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J × SM/J murine model. | Lawson HA et al. | — | 2011 | → |
| The past, present and future of reproductive skew theory and experiments. | Nonacs P et al. | — | 2011 | → |
| The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. | Wagner GP et al. | — | 2011 | → |
| The rise of yeast population genomics. | Liti G et al. | — | 2011 | → |
| The selfing syndrome: a model for studying the genetic and evolutionary basis of morphological adaptation in plants. | Sicard A et al. | — | 2011 | → |
| A catalogue of validated single nucleotide polymorphisms in bovine orthologs of mammalian imprinted genes and associations with beef production traits. | Magee DA et al. | — | 2010 | → |
| Adaptations to sexual selection and sexual conflict: insights from experimental evolution and artificial selection. | Edward DA et al. | — | 2010 | → |
| A quantitative trait locus on chr.4 regulates thymic involution. | Kumar R et al. | — | 2010 | → |
| Association mapping of seed oil content in Brassica napus and comparison with quantitative trait loci identified from linkage mapping. | Zou J et al. | — | 2010 | → |
| Association weight matrix for the genetic dissection of puberty in beef cattle. | Fortes MR et al. | — | 2010 | → |
| A strong quantitative trait locus for wing length on chromosome 2 in a wild population of great reed warblers. | Tarka M et al. | — | 2010 | → |
| Complex-trait analysis in plants. | Mitchell-Olds T | — | 2010 | → |
| Convergence in pigmentation at multiple levels: mutations, genes and function. | Manceau M et al. | — | 2010 | → |
| Decision neuroscience: neuroeconomics. | Smith DV et al. | — | 2010 | → |
| Disease association mapping in Drosophila can be replicated in the wild. | Wilfert L et al. | — | 2010 | → |
| Functional genomics complements quantitative genetics in identifying disease-gene associations. | Guan Y et al. | — | 2010 | → |
| Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/JxSM/J murine model. | Lawson HA et al. | — | 2010 | → |
| Genome-wide approaches to schizophrenia. | Duan J et al. | — | 2010 | → |
| Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans. | Li Y et al. | — | 2010 | → |
| Helicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain. | Kersulyte D et al. | — | 2010 | → |
| Hybrid incompatibility "snowballs" between Solanum species. | Moyle LC et al. | — | 2010 | → |
| Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisiae populations. | Will JL et al. | — | 2010 | → |
| Life course studies of psychopathology: consolidation and concern. | Shanahan MJ | — | 2010 | → |
| Mapping transcription mechanisms from multimodal genomic data. | Chang HH et al. | — | 2010 | → |
| Metabolic syndrome components in murine models. | Lawson HA et al. | — | 2010 | → |
| Modeling the aneuploidy control of cancer. | Li Y et al. | — | 2010 | → |
| Molecular basis of trait correlations. | Chen Y et al. | — | 2010 | → |
| Mutation and the evolution of ageing: from biometrics to system genetics. | Hughes KA | — | 2010 | → |
| Mutations and quantitative genetic variation: lessons from Drosophila. | Mackay TF | — | 2010 | → |
| Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. | Arya GH et al. | — | 2010 | → |
| On the origin of species: insights from the ecological genomics of lake whitefish. | Bernatchez L et al. | — | 2010 | → |
| Physiological insights gained from gene expression analysis in obesity and diabetes. | Keller MP et al. | — | 2010 | → |
| Predicting genetic modifier loci using functional gene networks. | Lee I et al. | — | 2010 | → |
| Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. | Magwire MM et al. | — | 2010 | → |
| Quantitative disease resistance and quantitative resistance Loci in breeding. | St Clair DA | — | 2010 | → |
| Rapid genomic characterization of the genus vitis. | Myles S et al. | — | 2010 | → |
| Serious limitations of the QTL/microarray approach for QTL gene discovery. | Verdugo RA et al. | — | 2010 | → |
| Statistical analysis of genetic interactions. | Yi N | — | 2010 | → |
| Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. | Jumbo-Lucioni P et al. | — | 2010 | → |
| Systems genetics analysis of gene-by-environment interactions in human cells. | Romanoski CE et al. | — | 2010 | → |
| The complexity of alcohol drinking: studies in rodent genetic models. | Crabbe JC et al. | — | 2010 | → |
| The maintenance of genetic variation for oviposition rate in two-spotted spider mites: inferences from artificial selection. | Tien NS et al. | — | 2010 | → |
| The role of gene expression in ecological speciation. | Pavey SA et al. | — | 2010 | → |
| Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana. | Bergelson J et al. | — | 2010 | → |
| Understanding and using quantitative genetic variation. | Hill WG | — | 2010 | → |
| Common disorders are quantitative traits. | Plomin R et al. | — | 2009 | → |
| Genetic variation of regulatory systems. | Dimas AS et al. | — | 2009 | → |
| Linking genotypes to phenotypes and fitness: how mechanistic biology can inform molecular ecology. | Dalziel AC et al. | — | 2009 | → |
| Measuring natural selection on genotypes and phenotypes in the wild. | Linnen CR et al. | — | 2009 | → |