Diet and the evolution of human amylase gene copy number variation.
- Authors
- Perry, George H; Dominy, Nathaniel J; Claw, Katrina G; Lee, Arthur S; Fiegler, Heike; Redon, Richard; Werner, John; Villanea, Fernando A; Mountain, Joanna L; Misra, Rajeev; Carter, Nigel P; Lee, Charles; Stone, Anne C
- Year
- 2007
- Journal
- Nature genetics
- PMID
- 17828263
- DOI
- 10.1038/ng2123
- PMCID
- PMC2377015
Starch consumption is a prominent characteristic of agricultural societies and hunter-gatherers in arid environments. In contrast, rainforest and circum-arctic hunter-gatherers and some pastoralists consume much less starch. This behavioral variation raises the possibility that different selective pressures have acted on amylase, the enzyme responsible for starch hydrolysis. We found that copy number of the salivary amylase gene (AMY1) is correlated positively with salivary amylase protein level and that individuals from populations with high-starch diets have, on average, more AMY1 copies than those with traditionally low-starch diets. Comparisons with other loci in a subset of these populations suggest that the extent of AMY1 copy number differentiation is highly unusual. This example of positive selection on a copy number-variable gene is, to our knowledge, one of the first discovered in the human genome. Higher AMY1 copy numbers and protein levels probably improve the digestion of starchy foods and may buffer against the fitness-reducing effects of intestinal disease.
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| Nutritional influences on enzyme activities in saliva of Asian and African elephants. | Boehlke C et al. | — | 2021 | → |
| Operationalizing niche construction theory with stone tools. | Iovita R et al. | — | 2021 | → |
| Paleolithic Diet-Effect on the Health Status and Performance of Athletes? | Frączek B et al. | — | 2021 | → |
| Pervasive cis effects of variation in copy number of large tandem repeats on local DNA methylation and gene expression. | Garg P et al. | — | 2021 | → |
| Polymorphisms of AMY1A gene and their association with growth, carcass traits and feed intake efficiency in chickens. | Zhang Z et al. | — | 2021 | → |
| Reduced odds of diabetes associated with high plasma salivary α-amylase activity in Qatari women: a cross-sectional study. | Al-Akl NS et al. | — | 2021 | → |
| Selection shapes the landscape of functional variation in wild house mice. | Lawal RA et al. | — | 2021 | → |
| Socio-eco-evolutionary dynamics in cities. | Des Roches S et al. | — | 2021 | → |
| Spectroscopic molecular-fingerprint profiling of saliva. | Buchan E et al. | — | 2021 | → |
| The Anthropocene: Exploring its origins, biology, and future. | Lucock M | — | 2021 | → |
| The role of the gut microbiota in the dietary niche expansion of fishing bats. | Aizpurua O et al. | — | 2021 | → |
| Toward a More Comprehensive View of α-Amylase across Decapods Crustaceans. | Rodríguez-Viera L et al. | — | 2021 | → |
| Understanding the Adaptive Evolutionary Histories of South American Ancient and Present-Day Populations via Genomics. | Lindo J et al. | — | 2021 | → |
| Vaginal microbiome: normalcy vs dysbiosis. | Saraf VS et al. | — | 2021 | → |
| Whole-Genome Sequencing Reveals Lactase Persistence Adaptation in European Dogs. | Liu YH et al. | — | 2021 | → |
| 3D printing of biomass-derived composites: application and characterization approaches. | Ji A et al. | — | 2020 | → |
| African Arowana Genome Provides Insights on Ancient Teleost Evolution. | Hao S et al. | — | 2020 | → |
| Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer's dementia. | Byman E et al. | — | 2020 | → |
| An Evolutionary Perspective on the Impact of Genomic Copy Number Variation on Human Health. | Saitou M et al. | — | 2020 | → |
| A population-based approach for gene prioritization in understanding complex traits. | Mezzavilla M et al. | — | 2020 | → |
| Association of AMY1A/AMY2A copy numbers and AMY1/AMY2 serum enzymatic activity with obesity in Mexican children. | Vázquez-Moreno M et al. | — | 2020 | → |
| Copy number variation detection in Chinese indigenous cattle by whole genome sequencing. | Mei C et al. | — | 2020 | → |
| Copy number variation in human genomes from three major ethno-linguistic groups in Africa. | Nyangiri OA et al. | — | 2020 | → |
| De novo duplication on Chromosome 19 observed in nuclear family displaying neurodevelopmental disorders. | Sjaarda CP et al. | — | 2020 | → |
| Evolutionary basis for the human diet: consequences for human health. | Andrews P et al. | — | 2020 | → |
| First echinoderm alpha-amylase from a tropical sea cucumber (Holothuria leucospilota): Molecular cloning, tissue distribution, cellular localization and functional production in a heterogenous E.coli system with codon optimization. | Wu X et al. | — | 2020 | → |
| Functional and population genetic features of copy number variations in two dairy cattle populations. | Lee YL et al. | — | 2020 | → |
| Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva. | Saitou M et al. | — | 2020 | → |
| Genetic Differences in Taste Receptors: Implications for the Food Industry. | Nolden AA et al. | — | 2020 | → |
| Genetics of Obesity in East Asians. | Sun C et al. | — | 2020 | → |
| Genome-Wide Analyses Provide Insights into the Scavenging Lifestyle of the Striped Hyena (<i>Hyaena hyaena</i>). | Zhou C et al. | — | 2020 | → |
| Genomic and biochemical evidence of dietary adaptation in a marine herbivorous fish. | Heras J et al. | — | 2020 | → |
| High plasma salivary α-amylase, but not high AMY1 copy number, associated with low obesity rate in Qatari adults: cross-sectional study. | Al-Akl N et al. | — | 2020 | → |
| Human and Nonhuman Primate Lineage-Specific Footprints in the Salivary Proteome. | Thamadilok S et al. | — | 2020 | → |
| Humanity's Best Friend: A Dog-Centric Approach to Addressing Global Challenges. | Sykes N et al. | — | 2020 | → |
| Identification and population genetic analyses of copy number variations in six domestic goat breeds and Bezoar ibexes using next-generation sequencing. | Guo J et al. | — | 2020 | → |
| Identification of a Candidate Starch Utilizing Strain of <i>Prevotella albensis</i> from Bovine Rumen. | Bandarupalli VVK et al. | — | 2020 | → |
| Integrative analysis of <i>APOL3</i> gene CNV for adult cattle stature. | Peng SJ et al. | — | 2020 | → |
| Interaction Effect Between Copy Number Variation in Salivary Amylase Locus (<i>AMY1</i>) and Starch Intake on Glucose Homeostasis in the Malmö Diet and Cancer Cohort. | Hamid AK et al. | — | 2020 | → |
| Live biotherapeutic products: the importance of a defined regulatory framework. | Cordaillat-Simmons M et al. | — | 2020 | → |
| Low AMY1 Copy Number Is Cross-Sectionally Associated to an Inflammation-Related Lipidomics Signature in Overweight and Obese Individuals. | Mayneris-Perxachs J et al. | — | 2020 | → |
| Microbial control of host gene regulation and the evolution of host-microbiome interactions in primates. | Grieneisen L et al. | — | 2020 | → |
| Optimal integration between host physiology and functions of the gut microbiome. | Fontaine SS et al. | — | 2020 | → |
| Oral physiological and biochemical characteristics of different dietary habit groups II: Comparison of oral salivary biochemical properties of Chinese Mongolian and Han Young adults. | Zhang D et al. | — | 2020 | → |
| Origins and genetic legacy of prehistoric dogs. | Bergström A et al. | — | 2020 | → |
| Pretreatment Prevotella-to-Bacteroides ratio and salivary amylase gene copy number as prognostic markers for dietary weight loss. | Hjorth MF et al. | — | 2020 | → |
| Rapid Dietary Shift in <i>Podarcis siculus</i> Resulted in Localized Changes in Gut Function. | Wehrle BA et al. | — | 2020 | → |
| Salivary AMY1 Copy Number Variation Modifies Age-Related Type 2 Diabetes Risk. | Liu Y et al. | — | 2020 | → |
| Salivary Biomarkers for Diagnosis of Inflammatory Bowel Diseases: A Systematic Review. | Nijakowski K et al. | — | 2020 | → |
| Starch Digestion-Related Amylase Genetic Variants, Diet, and Changes in Adiposity: Analyses in Prospective Cohort Studies and a Randomized Dietary Intervention. | Heianza Y et al. | — | 2020 | → |
| Strategies in herbivory by mammals revisited: The role of liver metabolism in a juniper specialist (Neotoma stephensi) and a generalist (Neotoma albigula). | Orr TJ et al. | — | 2020 | → |
| Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen). | Riggs ER et al. | — | 2020 | → |
| The amylase gene cluster in house mice (Mus musculus) was subject to repeated introgression including the rescue of a pseudogene. | Linnenbrink M et al. | — | 2020 | → |
| The Epistemology of Evolutionary Psychology Offers a Rapprochement to Cultural Psychology. | Saad G | — | 2020 | → |
| The origin and diversification of a novel protein family in venomous snakes. | Giorgianni MW et al. | — | 2020 | → |
| The role of the microbiota in human genetic adaptation. | Suzuki TA et al. | — | 2020 | → |
| Unveiling Human Non-Random Genome Editing Mechanisms Activated in Response to Chronic Environmental Changes: I. Where Might These Mechanisms Come from and What Might They Have Led To? | Zamai L | — | 2020 | → |
| Variation of human salivary alpha-amylase proteoforms in three stimulation models. | Contreras-Aguilar MD et al. | — | 2020 | → |
| WEIRD bodies: mismatch, medicine and missing diversity. | Gurven MD et al. | — | 2020 | → |
| Adaptive archaic introgression of copy number variants and the discovery of previously unknown human genes. | Hsieh P et al. | — | 2019 | → |
| Analysis of copy number variations induced by ultrashort electron beam radiation in human leukocytes in vitro. | Harutyunyan T et al. | — | 2019 | → |
| Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations. | Deng L et al. | — | 2019 | → |
| An Interrogation of Shared and Unique Copy Number Variants Across Genetically Distinct Zebrafish Strains. | Holden LA et al. | — | 2019 | → |
| A Novel Gene Coding γ-Aminobutyric Acid Transporter May Improve the Tolerance of <i>Populus euphratica</i> to Adverse Environments. | Bai X et al. | — | 2019 | → |
| Association between salivary amylase enzyme activity and obesity in Saudi Arabia. | Aldossari NM et al. | — | 2019 | → |
| Association of Salivary Amylase (<i>AMY1</i>) Gene Copy Number with Obesity in Alabama Elementary School Children. | Venkatapoorna CMK et al. | — | 2019 | → |
| Characterization and evolutionary dynamics of complex regions in eukaryotic genomes. | Ranz J et al. | — | 2019 | → |
| Cooked starchy food in hearths ca. 120 kya and 65 kya (MIS 5e and MIS 4) from Klasies River Cave, South Africa. | Larbey C et al. | — | 2019 | → |
| Copy Number Variation Mapping and Genomic Variation of Autochthonous and Commercial Turkey Populations. | Strillacci MG et al. | — | 2019 | → |
| DNA methylation in satellite repeats disorders. | Francastel C et al. | — | 2019 | → |
| Domestication of Industrial Microbes. | Steensels J et al. | — | 2019 | → |
| Effect of Oral Physiology Parameters on In-Mouth Aroma Compound Release Using Lipoprotein Matrices: An In Vitro Approach. | Tarrega A et al. | — | 2019 | → |
| Ethnicity, gender and physiological parameters: Their effect on in vivo flavour release and perception during chewing gum consumption. | Pedrotti M et al. | — | 2019 | → |
| Evolutionary Dynamics of Structural Variation at a Key Locus for Color Pattern Diversification in Cichlid Fishes. | Kratochwil CF et al. | — | 2019 | → |
| Examination of the temporal and spatial dynamics of the gut microbiome in newborn piglets reveals distinct microbial communities in six intestinal segments. | Liu Y et al. | — | 2019 | → |
| Expression Profile of the Digestive Enzymes of <i>Manis javanica</i> Reveals Its Adaptation to Diet Specialization. | Zhang F et al. | — | 2019 | → |
| Gene copy number variations involved in balsam poplar (Populus balsamifera L.) adaptive variations. | Prunier J et al. | — | 2019 | → |
| Genetics, adaptation to environmental changes and archaic admixture in the pathogenesis of diabetes mellitus in Indigenous Australians. | Brzozowska MM et al. | — | 2019 | → |
| Genome-Wide Genotype-Expression Relationships Reveal Both Copy Number and Single Nucleotide Differentiation Contribute to Differential Gene Expression between Stickleback Ecotypes. | Huang Y et al. | — | 2019 | → |
| Genomic evidence for shared common ancestry of East African hunting-gathering populations and insights into local adaptation. | Scheinfeldt LB et al. | — | 2019 | → |
| How are macronutrient intake, BMI, ethnicity, age, and gender related to the composition of unstimulated saliva? A case study. | Mosca AC et al. | — | 2019 | → |
| Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes. | Poole AC et al. | — | 2019 | → |
| Increased Inflammation and Cardiometabolic Risk in Individuals with Low <i>AMY1</i> Copy Numbers. | Marquina C et al. | — | 2019 | → |
| Independent amylase gene copy number bursts correlate with dietary preferences in mammals. | Pajic P et al. | — | 2019 | → |
| Microbiome and diversity indices during blood stem cells transplantation - new perspectives? | Parco S et al. | — | 2019 | → |
| Mitochondrial DNA, a Powerful Tool to Decipher Ancient Human Civilization from Domestication to Music, and to Uncover Historical Murder Cases. | Merheb M et al. | — | 2019 | → |
| Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex. | Chronister WD et al. | — | 2019 | → |
| New insights into the origin and evolution of α-amylase genes in green plants. | Ju L et al. | — | 2019 | → |
| No association between AMY2B gene copy number and obesity risk in Labrador retriever dogs. | Antkowiak M et al. | — | 2019 | → |
| Nutrition and its role in human evolution. | James WPT et al. | — | 2019 | → |
| Of starch and spit. | Janiak MC | — | 2019 | → |
| Oral carbohydrate sensing: Beyond sweet taste. | Lim J et al. | — | 2019 | → |
| Oral lipolysis and its association with diet and the perception and digestion of lipids: A systematic literature review. | Brignot H et al. | — | 2019 | → |
| Oro-gastro-intestinal digestion of starch in white bread, wheat-based and gluten-free pasta: Unveiling the contribution of human salivary α-amylase. | Freitas D et al. | — | 2019 | → |
| Phenolic distribution, antioxidant activity, and enzyme inhibitory properties of eggplant (Solanum aethiopicum) cultivated in two different locations within Nigeria. | Nwanna EE et al. | — | 2019 | → |
| Polar bear evolution is marked by rapid changes in gene copy number in response to dietary shift. | Rinker DC et al. | — | 2019 | → |
| Regulation plays a multifaceted role in the retention of gene duplicates. | Hallin J et al. | — | 2019 | → |
| Resolving the Insertion Sites of Polymorphic Duplications Reveals a HERC2 Haplotype under Selection. | Saitou M et al. | — | 2019 | → |
| Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study. | Valsesia A et al. | — | 2019 | → |
| Self-Assembled STrap for Global Proteomics and Salivary Biomarker Discovery. | Lin YH et al. | — | 2019 | → |
| Shifting Climates, Foods, and Diseases: The Human Microbiome through Evolution. | Amato KR et al. | — | 2019 | → |
| Structural variant calling: the long and the short of it. | Mahmoud M et al. | — | 2019 | → |
| Taste responsiveness of Western chimpanzees (Pan troglodytes verus) to five food-associated saccharides. | Norlén E et al. | — | 2019 | → |
| The Genetic Basis of Toxin Biosynthesis in Dinoflagellates. | Verma A et al. | — | 2019 | → |
| The Iceberg under Water: Unexplored Complexity of Chromoanagenesis in Congenital Disorders. | Zepeda-Mendoza CJ et al. | — | 2019 | → |
| Whole-genome re-sequencing reveals the impact of the interaction of copy number variants of the rhg1 and Rhg4 genes on broad-based resistance to soybean cyst nematode. | Patil GB et al. | — | 2019 | → |
| You are what you eat: diet, health and the gut microbiota. | Zmora N et al. | — | 2019 | → |
| Adaptive deletion in resistance gene duplications in the malaria vector <i>Anopheles gambiae</i>. | Assogba BS et al. | — | 2018 | → |
| Age-associated microbiome shows the giant panda lives on hemicelluloses, not on cellulose. | Zhang W et al. | — | 2018 | → |
| A genome-wide characterization of copy number variations in native populations of Peninsular Malaysia. | Fu R et al. | — | 2018 | → |
| Altered Salivary Alpha-Amylase Secretion in Patients with Ulcerative Colitis. | Xu Z et al. | — | 2018 | → |
| AMYCNE: Confident copy number assessment using whole genome sequencing data. | Eisfeldt J et al. | — | 2018 | → |
| Analysis of Population-Genetic Properties of Copy Number Variations. | Xu L et al. | — | 2018 | → |
| A population genomic characterization of copy number variation in the opportunistic fungal pathogen Aspergillus fumigatus. | Zhao S et al. | — | 2018 | → |
| A review of metabolic potential of human gut microbiome in human nutrition. | Yadav M et al. | — | 2018 | → |
| Associations of GBP2 gene copy number variations with growth traits and transcriptional expression in Chinese cattle. | Zhang GM et al. | — | 2018 | → |
| Comparative proteomic study of dog and human saliva. | Sanguansermsri P et al. | — | 2018 | → |
| Complex Haplotypes of <i>GSTM1</i> Gene Deletions Harbor Signatures of a Selective Sweep in East Asian Populations. | Saitou M et al. | — | 2018 | → |
| Copy Number Variation in Fungi and Its Implications for Wine Yeast Genetic Diversity and Adaptation. | Steenwyk JL et al. | — | 2018 | → |
| Detecting differential copy number variation between groups of samples. | Lowe CB et al. | — | 2018 | → |
| Dietary carbohydrates: role of quality and quantity in chronic disease. | Ludwig DS et al. | — | 2018 | → |
| Divergent patterns of genic copy number variation in KCNIP1 gene reveal risk locus of type 2 diabetes in Chinese population. | Xu Y et al. | — | 2018 | → |
| Duplication of hsp-110 Is Implicated in Differential Success of Globodera Species under Climate Change. | Jones LM et al. | — | 2018 | → |
| Elevated salivary alpha-amylase levels at awakening in patients with depression. | Bauduin SEEC et al. | — | 2018 | → |
| Evolutionary and Medical Consequences of Archaic Introgression into Modern Human Genomes. | Dolgova O et al. | — | 2018 | → |
| Evolution of Acidic Mammalian Chitinase Genes (CHIA) Is Related to Body Mass and Insectivory in Primates. | Janiak MC et al. | — | 2018 | → |
| FADS1 and the Timing of Human Adaptation to Agriculture. | Mathieson S et al. | — | 2018 | → |
| Genome plasticity in response to stress in Tetrahymena thermophila: selective and reversible chromosome amplification and paralogous expansion of metallothionein genes. | de Francisco P et al. | — | 2018 | → |
| High AMY1 copy number protects against obesity in Portuguese young adults. | Pinho S et al. | — | 2018 | → |
| Human amylase gene copy number variation as a determinant of metabolic state. | Elder PJD et al. | — | 2018 | → |
| Kin Selection and Male Homosexual Preference in Indonesia. | Nila S et al. | — | 2018 | → |
| KoVariome: Korean National Standard Reference Variome database of whole genomes with comprehensive SNV, indel, CNV, and SV analyses. | Kim J et al. | — | 2018 | → |
| Low Salivary Amylase Gene (<i>AMY1</i>) Copy Number Is Associated with Obesity and Gut <i>Prevotella</i> Abundance in Mexican Children and Adults. | León-Mimila P et al. | — | 2018 | → |
| Main effects of human saliva on flavour perception and the potential contribution to food consumption. | Muñoz-González C et al. | — | 2018 | → |
| Molecular cytogenetics to characterize mechanisms of gene duplication in pesticide resistance. | Jugulam M et al. | — | 2018 | → |
| On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations. | Qasim A et al. | — | 2018 | → |
| Plant-based diets for dogs. | Dodd SAS et al. | — | 2018 | → |
| Pleistocene dental calculus: Recovering information on Paleolithic food items, medicines, paleoenvironment and microbes. | Hardy K et al. | — | 2018 | → |
| Precision behavioral medicine: Implications of genetic and genomic discoveries for behavioral weight loss treatment. | McCaffery JM | — | 2018 | → |
| Proteomic evidence of dietary sources in ancient dental calculus. | Hendy J et al. | — | 2018 | → |
| Rapid Gene Family Evolution of a Nematode Sperm Protein Despite Sequence Hyper-conservation. | Kasimatis KR et al. | — | 2018 | → |
| Reflections on nutrition in biological anthropology. | Dufour DL et al. | — | 2018 | → |
| Role of cytochrome P450 2B sequence variation and gene copy number in facilitating dietary specialization in mammalian herbivores. | Kitanovic S et al. | — | 2018 | → |
| Sequence Composition and Evolution of Mammalian B Chromosomes. | Rubtsov NB et al. | — | 2018 | → |
| Signatures of human-commensalism in the house sparrow genome. | Ravinet M et al. | — | 2018 | → |
| Tales of Human Migration, Admixture, and Selection in Africa. | Schlebusch CM et al. | — | 2018 | → |
| The Amylases of Insects. | Da Lage JL | — | 2018 | → |
| The evaluation and validation of Phadebas<sup>®</sup> paper as a presumptive screening tool for saliva on forensic exhibits. | Wornes DJ et al. | — | 2018 | → |
| The evolutionary fate of heterogeneous gene duplications: A precarious overdominant equilibrium between environment, sublethality and complementation. | Milesi P et al. | — | 2018 | → |
| The genetic prehistory of the Andean highlands 7000 years BP though European contact. | Lindo J et al. | — | 2018 | → |
| The genomics of selenium: Its past, present and future. | Davy T et al. | — | 2018 | → |
| The Neutral Theory in Light of Natural Selection. | Kern AD et al. | — | 2018 | → |
| The physiologic and phenotypic significance of variation in human amylase gene copy number. | Atkinson FS et al. | — | 2018 | → |
| A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. | Gao C et al. | — | 2017 | → |
| Analysis of Copy Number Variation in the Abp Gene Regions of Two House Mouse Subspecies Suggests Divergence during the Gene Family Expansions. | Pezer Ž et al. | — | 2017 | → |
| Ancestors' dietary patterns and environments could drive positive selection in genes involved in micronutrient metabolism-the case of cofactor transporters. | Parolo S et al. | — | 2017 | → |
| Assessing genome-wide copy number variation in the Han Chinese population. | Lu J et al. | — | 2017 | → |
| Associations between food consumption patterns and saliva composition: Specificities of eating difficulties children. | Morzel M et al. | — | 2017 | → |
| Association study and expression analysis of CYP4A11 gene copy number variation in Chinese cattle. | Yang M et al. | — | 2017 | → |
| Benign, Pathogenic and Copy Number Variations of Unknown Clinical Significance in Patients with Congenital Malformations and Developmental Delay. | Mihaylova M et al. | — | 2017 | → |
| Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation? | Gertsch J | — | 2017 | → |
| Changes in human skull morphology across the agricultural transition are consistent with softer diets in preindustrial farming groups. | Katz DC et al. | — | 2017 | → |
| CNVs into the wild: screening the genomes of conifer trees (Picea spp.) reveals fewer gene copy number variations in hybrids and links to adaptation. | Prunier J et al. | — | 2017 | → |
| Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity. | Carpenter D et al. | — | 2017 | → |
| Correlates and catalysts of hominin evolution in Africa. | McKee JK | — | 2017 | → |
| Dietary starch intake modifies the relation between copy number variation in the salivary amylase gene and BMI. | Rukh G et al. | — | 2017 | → |
| Differences in AMY1 Gene Copy Numbers Derived from Blood, Buccal Cells and Saliva Using Quantitative and Droplet Digital PCR Methods: Flagging the Pitfall. | Ooi DS et al. | — | 2017 | → |
| Differences in nutritional quality between wild and domesticated forms of barley and emmer wheat. | Hebelstrup KH | — | 2017 | → |
| Diverse Cis-Regulatory Mechanisms Contribute to Expression Evolution of Tandem Gene Duplicates. | Baudouin-Gonzalez L et al. | — | 2017 | → |
| Does diet influence salivary enzyme activities in elephant species? | Boehlke C et al. | — | 2017 | → |
| Dosage-sensitive genes in evolution and disease. | Rice AM et al. | — | 2017 | → |
| Extensive Copy Number Variation in Fermentation-Related Genes Among <i>Saccharomyces cerevisiae</i> Wine Strains. | Steenwyk J et al. | — | 2017 | → |
| Gene copy number variations in adaptive evolution: The genomic distribution of gene copy number variations revealed by genetic mapping and their adaptive role in an undomesticated species, white spruce (Picea glauca). | Prunier J et al. | — | 2017 | → |
| Genome-wide analysis reveals differential selection involved with copy number variation in diverse Chinese Cattle. | Yang L et al. | — | 2017 | → |
| Harnessing ancient genomes to study the history of human adaptation. | Marciniak S et al. | — | 2017 | → |
| Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans. | Bohn T et al. | — | 2017 | → |
| Identifying genetic variants that affect viability in large cohorts. | Mostafavi H et al. | — | 2017 | → |
| Impact of salivary enzyme activity on the oral perception of starch containing foods. | Bridges J et al. | — | 2017 | → |
| Kiwifruit actinidin digests salivary amylase but not gastric lipase. | Martin H et al. | — | 2017 | → |
| Nutrigenomics in the modern era. | Mathers JC | — | 2017 | → |
| Opsins have evolved under the permanent heterozygote model: insights from phylotranscriptomics of Odonata. | Suvorov A et al. | — | 2017 | → |
| Oral Digestion and Perception of Starch: Effects of Cooking, Tasting Time, and Salivary α-Amylase Activity. | Lapis TJ et al. | — | 2017 | → |
| Rapid Functional and Sequence Differentiation of a Tandemly Repeated Species-Specific Multigene Family in Drosophila. | Clifton BD et al. | — | 2017 | → |
| Recurrent Rearrangements of Human Amylase Genes Create Multiple Independent CNV Series. | Shwan NAA et al. | — | 2017 | → |
| Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach. | Bonnefond A et al. | — | 2017 | → |
| Rethinking the starch digestion hypothesis for AMY1 copy number variation in humans. | Fernández CI et al. | — | 2017 | → |
| Schizophrenia and the dynamic genome. | Sullivan PF | — | 2017 | → |
| Starch Digestion-Related Amylase Genetic Variant Affects 2-Year Changes in Adiposity in Response to Weight-Loss Diets: The POUNDS Lost Trial. | Heianza Y et al. | — | 2017 | → |
| Survival and divergence in a small group: The extraordinary genomic history of the endangered Apennine brown bear stragglers. | Benazzo A et al. | — | 2017 | → |
| Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection. | Al-Daghri NM et al. | — | 2017 | → |
| Tailoring Nutritional Advice for Mexicans Based on Prevalence Profiles of Diet-Related Adaptive Gene Polymorphisms. | Ojeda-Granados C et al. | — | 2017 | → |
| Tooth Be Told, Genetics Influences Oral Microbiome. | Davenport ER | — | 2017 | → |
| A Highly Polymorphic Copy Number Variant in the NSF Gene is Associated with Cocaine Dependence. | Cabana-Domínguez J et al. | — | 2016 | → |
| Analysis on evolutionary relationship of amylases from archaea, bacteria and eukaryota. | Yan S et al. | — | 2016 | → |
| An introduction to niche construction theory. | Laland K et al. | — | 2016 | → |
| Arabidopsis thaliana population analysis reveals high plasticity of the genomic region spanning MSH2, AT3G18530 and AT3G18535 genes and provides evidence for NAHR-driven recurrent CNV events occurring in this location. | Zmienko A et al. | — | 2016 | → |
| Behavioral measures of risk tasking, sensation seeking and sensitivity to reward may reflect different motivations for spicy food liking and consumption. | Byrnes NK et al. | — | 2016 | → |
| Between-species differences in gene copy number are enriched among functions critical for adaptive evolution in Arabidopsis halleri. | Suryawanshi V et al. | — | 2016 | → |
| Complex Copy Number Variation of AMY1 does not Associate with Obesity in two East Asian Cohorts. | Yong RY et al. | — | 2016 | → |
| Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest. | Steenwyk JL et al. | — | 2016 | → |
| Diet adaptation in dog reflects spread of prehistoric agriculture. | Arendt M et al. | — | 2016 | → |
| Dietary Variation and Evolution of Gene Copy Number among Dog Breeds. | Reiter T et al. | — | 2016 | → |
| Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive. | Mishra S et al. | — | 2016 | → |
| Digestive enzymes of human and nonhuman primates. | Janiak MC | — | 2016 | → |
| Direct Characterization of the Maize Starch Synthase IIa Product Shows Maltodextrin Elongation Occurs at the Non-reducing End. | Larson ME et al. | — | 2016 | → |
| Diversity and population-genetic properties of copy number variations and multicopy genes in cattle. | Bickhart DM et al. | — | 2016 | → |
| Effects of Linked Selective Sweeps on Demographic Inference and Model Selection. | Schrider DR et al. | — | 2016 | → |
| Elevated Gene Copy Number Does Not Always Explain Elevated Amylase Activities in Fishes. | German DP et al. | — | 2016 | → |
| Evidence for the fixation of gene duplications by positive selection in Drosophila. | Cardoso-Moreira M et al. | — | 2016 | → |
| Evidence for the Paleoethnobotany of the Neanderthal: A Review of the Literature. | Shipley GP et al. | — | 2016 | → |
| Evolutionary change in physiological phenotypes along the human lineage. | Vining AQ et al. | — | 2016 | → |
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| Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia. | Galinsky KJ et al. | — | 2016 | → |
| Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions. | Hoban S et al. | — | 2016 | → |
| Foraging potential of underground storage organ plants in the southern Cape, South Africa. | Singels E et al. | — | 2016 | → |
| Gene Duplication and Gene Expression Changes Play a Role in the Evolution of Candidate Pollen Feeding Genes in Heliconius Butterflies. | Smith G et al. | — | 2016 | → |
| Genes and Small RNA Transcripts Exhibit Dosage-Dependent Expression Pattern in Maize Copy-Number Alterations. | Zuo T et al. | — | 2016 | → |
| Genetic Evidence of Human Adaptation to a Cooked Diet. | Carmody RN et al. | — | 2016 | → |
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| GWAS-identified schizophrenia risk SNPs at TSPAN18 are highly diverged between Europeans and East Asians. | Liu J et al. | — | 2016 | → |
| How to make stone soup: Is the "Paleo diet" a missed opportunity for anthropologists? | Chang ML et al. | — | 2016 | → |
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| <i>Amy2B</i> copy number variation reveals starch diet adaptations in ancient European dogs. | Ollivier M et al. | — | 2016 | → |
| Inferences of African evolutionary history from genomic data. | Beltrame MH et al. | — | 2016 | → |
| Interactions between Starch, Lipids, and Proteins in Foods: Microstructure Control for Glycemic Response Modulation. | Parada J et al. | — | 2016 | → |
| Lactobacilli Dominance and Vaginal pH: Why Is the Human Vaginal Microbiome Unique? | Miller EA et al. | — | 2016 | → |
| Low AMY1 Gene Copy Number Is Associated with Increased Body Mass Index in Prepubertal Boys. | Marcovecchio ML et al. | — | 2016 | → |
| Low serum amylase and obesity, diabetes and metabolic syndrome: A novel interpretation. | Nakajima K | — | 2016 | → |
| Metabolomic Profile of Low-Copy Number Carriers at the Salivary α-Amylase Gene Suggests a Metabolic Shift Toward Lipid-Based Energy Production. | Arredouani A et al. | — | 2016 | → |
| Molecular, Biochemical, and Dietary Regulation Features of α-Amylase in a Carnivorous Crustacean, the Spiny Lobster Panulirus argus. | Rodríguez-Viera L et al. | — | 2016 | → |
| Parallelism and Epistasis in Skeletal Evolution Identified through Use of Phylogenomic Mapping Strategies. | Daane JM et al. | — | 2016 | → |
| Population-genetic properties of differentiated copy number variations in cattle. | Xu L et al. | — | 2016 | → |
| Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure. | Galinsky KJ et al. | — | 2016 | → |
| Population Structure Shapes Copy Number Variation in Malaria Parasites. | Cheeseman IH et al. | — | 2016 | → |
| Relationships Between Fasting Serum Amylase and Ghrelin or Peptide YY3-36 Levels in Healthy Men. | Tak YJ et al. | — | 2016 | → |
| Robust Yet Fragile: Expression Noise, Protein Misfolding, and Gene Dosage in the Evolution of Genomes. | Pires JC et al. | — | 2016 | → |
| Salivary Alpha-Amylase Correlates with Subjective Heat Pain Perception. | Wittwer A et al. | — | 2016 | → |
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| The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications. | Assogba BS et al. | — | 2016 | → |
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| The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan divergence. | Pajic P et al. | — | 2016 | → |
| The role of digestive factors in determining glycemic response in a multiethnic Asian population. | Tan VM et al. | — | 2016 | → |
| Using Genotype-Based Recall to Estimate the Effects of AMY1 Copy Number Variation in Substrate Metabolism. | Franks PW et al. | — | 2016 | → |
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| A decade of structural variants: description, history and methods to detect structural variation. | Escaramís G et al. | — | 2015 | → |
| Age Differences of Salivary Alpha-Amylase Levels of Basal and Acute Responses to Citric Acid Stimulation Between Chinese Children and Adults. | Yang ZM et al. | — | 2015 | → |
| Assessing digestibility of Hadza tubers using a dynamic in-vitro model. | Schnorr SL et al. | — | 2015 | → |
| Association between salivary amylase (AMY1) gene copy numbers and insulin resistance in asymptomatic Korean men. | Choi YJ et al. | — | 2015 | → |
| Attenuated acute salivary α-amylase responses to gustatory stimulation with citric acid in thin children. | Chen LH et al. | — | 2015 | → |
| Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children. | Mejía-Benítez MA et al. | — | 2015 | → |
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| Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes. | Gibbons JG et al. | — | 2015 | → |
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| Copy number variation in the speciation of pigs: a possible prominent role for olfactory receptors. | Paudel Y et al. | — | 2015 | → |
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| Cross-species comparison of mammalian saliva using an LC-MALDI based proteomic approach. | de Sousa-Pereira P et al. | — | 2015 | → |
| Dental calculus evidence of Taï Forest Chimpanzee plant consumption and life history transitions. | Power RC et al. | — | 2015 | → |
| Developmental genes significantly afflicted by aberrant promoter methylation and somatic mutation predict overall survival of late-stage colorectal cancer. | An N et al. | — | 2015 | → |
| Discovery of copy number variants by multiplex amplifiable probe hybridization (MAPH) in candidate pigmentation genes. | López S et al. | — | 2015 | → |
| Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses. | Toufighi K et al. | — | 2015 | → |
| Divergence patterns of genic copy number variation in natural populations of the house mouse (Mus musculus domesticus) reveal three conserved genes with major population-specific expansions. | Pezer Ž et al. | — | 2015 | → |
| DNA analysis of ancient dogs of the Americas: identifying possible founding haplotypes and reconstructing population histories. | Witt KE et al. | — | 2015 | → |
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| Dynamics of copy number variation in host races of the pea aphid. | Duvaux L et al. | — | 2015 | → |
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| Effect of ethnicity on glycaemic index: a systematic review and meta-analysis. | Wolever TM et al. | — | 2015 | → |
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| Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort. | Silver MJ et al. | — | 2015 | → |
| Evolutionary impact of transposable elements on genomic diversity and lineage-specific innovation in vertebrates. | Warren IA et al. | — | 2015 | → |
| Evolution of the rapidly mutating human salivary agglutinin gene (DMBT1) and population subsistence strategy. | Polley S et al. | — | 2015 | → |
| Expanding Duplication of Free Fatty Acid Receptor-2 (GPR43) Genes in the Chicken Genome. | Meslin C et al. | — | 2015 | → |
| Exploring the relationship between lifestyles, diets and genetic adaptations in humans. | Valente C et al. | — | 2015 | → |
| Fluorescent protein-mediated colour polymorphism in reef corals: multicopy genes extend the adaptation/acclimatization potential to variable light environments. | Gittins JR et al. | — | 2015 | → |
| Genetic adaptation to levels of dietary selenium in recent human history. | White L et al. | — | 2015 | → |
| Genetic Determinants of Type 2 Diabetes in Asians. | Qi Q et al. | — | 2015 | → |
| Genome-based nutrition: an intervention strategy for the prevention and treatment of obesity and nonalcoholic steatohepatitis. | Roman S et al. | — | 2015 | → |
| Genomic approaches to studying human-specific developmental traits. | Franchini LF et al. | — | 2015 | → |
| Genotyping of common SIRPB1 copy number variant using Paralogue Ratio Test coupled to MALDI-MS quantification. | Royo JL et al. | — | 2015 | → |
| Haplotype phasing and inheritance of copy number variants in nuclear families. | Palta P et al. | — | 2015 | → |
| Human adaptation to arsenic-rich environments. | Schlebusch CM et al. | — | 2015 | → |
| Humans as cucinivores: comparisons with other species. | Furness JB et al. | — | 2015 | → |
| Inferring the genetic history of lactase persistence along the Italian peninsula from a large genomic interval surrounding the LCT gene. | De Fanti S et al. | — | 2015 | → |
| Influences of AMY1 gene copy number and protein expression on salivary alpha-amylase activity before and after citric acid stimulation in splenic asthenia children. | Yang Z et al. | — | 2015 | → |
| Insights into hominin phenotypic and dietary evolution from ancient DNA sequence data. | Perry GH et al. | — | 2015 | → |
| Investigating the mechanisms of amylolysis of starch granules by solution-state NMR. | Baldwin AJ et al. | — | 2015 | → |
| Isolation and characterization of starch from industrial fresh pasta by-product and its potential use in sugar-snap cookie making. | Ellouzi SZ et al. | — | 2015 | → |
| Large multiallelic copy number variations in humans. | Handsaker RE et al. | — | 2015 | → |
| Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland. | Viljakainen H et al. | — | 2015 | → |
| Metagenome Sequencing of the Hadza Hunter-Gatherer Gut Microbiota. | Rampelli S et al. | — | 2015 | → |
| More than one way to be an herbivore: convergent evolution of herbivory using different digestive strategies in prickleback fishes (Stichaeidae). | German DP et al. | — | 2015 | → |
| Multi-omics profiling reveals that eating difficulties developed consecutively to artificial nutrition in the neonatal period are associated to specific saliva composition. | Morzel M et al. | — | 2015 | → |
| Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals. | Pontremoli C et al. | — | 2015 | → |
| Natural selection on HFE in Asian populations contributes to enhanced non-heme iron absorption. | Ye K et al. | — | 2015 | → |
| Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes. | Carpenter D et al. | — | 2015 | → |
| Our landscapes, our livestock, ourselves: Restoring broken linkages among plants, herbivores, and humans with diets that nourish and satiate. | Provenza FD et al. | — | 2015 | → |
| Pacific Populations, Metabolic Disease and 'Just-So Stories': A Critique of the 'Thrifty Genotype' Hypothesis in Oceania. | Gosling AL et al. | — | 2015 | → |
| Rapid evolution of recombinant Saccharomyces cerevisiae for Xylose fermentation through formation of extra-chromosomal circular DNA. | Demeke MM et al. | — | 2015 | → |
| Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans. | Farslow JC et al. | — | 2015 | → |
| Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. | Nagasaki M et al. | — | 2015 | → |
| Reception of Aversive Taste. | Lunceford BE et al. | — | 2015 | → |
| Salivary amylase - The enzyme of unspecialized euryphagous animals. | Boehlke C et al. | — | 2015 | → |
| Salivary Composition Is Associated with Liking and Usual Nutrient Intake. | Méjean C et al. | — | 2015 | → |
| Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity. | Usher CL et al. | — | 2015 | → |
| Structural variation mutagenesis of the human genome: Impact on disease and evolution. | Lupski JR | — | 2015 | → |
| The functional basis of adaptive evolution in chemostats. | Gresham D et al. | — | 2015 | → |
| The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities. | Chong JX et al. | — | 2015 | → |
| The impact of human copy number variation on gene expression. | Gamazon ER et al. | — | 2015 | → |
| THE IMPORTANCE OF DIETARY CARBOHYDRATE IN HUMAN EVOLUTION. | Hardy K et al. | — | 2015 | → |
| The roles of AMY1 copies and protein expression in human salivary α-amylase activity. | Yang ZM et al. | — | 2015 | → |
| Trypsin isozymes in the lobster Panulirus argus (Latreille, 1804): from molecules to physiology. | Perera E et al. | — | 2015 | → |
| Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence. | Morton ER et al. | — | 2015 | → |
| Amylase activity is associated with AMY2B copy numbers in dog: implications for dog domestication, diet and diabetes. | Arendt M et al. | — | 2014 | → |
| Ancient human genomes suggest three ancestral populations for present-day Europeans. | Lazaridis I et al. | — | 2014 | → |
| Baboon feeding ecology informs the dietary niche of Paranthropus boisei. | Macho GA | — | 2014 | → |
| Blood, bulbs, and bunodonts: on evolutionary ecology and the diets of Ardipithecus, Australopithecus, and early Homo. | Sayers K et al. | — | 2014 | → |
| Compilation of copy number variants identified in phenotypically normal and parous Japanese women. | Migita O et al. | — | 2014 | → |
| Copy number variants and selective sweeps in natural populations of the house mouse (Mus musculus domesticus). | Bryk J et al. | — | 2014 | → |
| Copy number variations burden on miRNA genes reveals layers of complexities involved in the regulation of pathways and phenotypic expression. | Veerappa AM et al. | — | 2014 | → |
| Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European. | Olalde I et al. | — | 2014 | → |
| Detection of copy number variations and their effects in Chinese bulls. | Zhang L et al. | — | 2014 | → |
| Diet and our genetic legacy in the recent anthropocene: a Darwinian perspective to nutritional health. | Lucock MD et al. | — | 2014 | → |
| Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. | Brahmachary M et al. | — | 2014 | → |
| Drosophila duplicate genes evolve new functions on the fly. | Assis R | — | 2014 | → |
| Effect of dietary fiber/starch balance on the cecal proteome of growing rabbits. | Zhu Y et al. | — | 2014 | → |
| Exome sequencing and arrayCGH detection of gene sequence and copy number variation between ILS and ISS mouse strains. | Dumas L et al. | — | 2014 | → |
| Expansion of a 12-kb VNTR containing the REXO1L1 gene cluster underlies the microscopically visible euchromatic variant of 8q21.2. | Tyson C et al. | — | 2014 | → |
| Extensive copy-number variation of young genes across stickleback populations. | Chain FJ et al. | — | 2014 | → |
| Extensive copy number variations in admixed Indian population of African ancestry: potential involvement in adaptation. | Narang A et al. | — | 2014 | → |
| Extensive error in the number of genes inferred from draft genome assemblies. | Denton JF et al. | — | 2014 | → |
| GENE-dosage effects on fitness in recent adaptive duplications: ace-1 in the mosquito Culex pipiens. | Labbé P et al. | — | 2014 | → |
| Gene duplication and phenotypic changes in the evolution of mammalian metabolic networks. | Bekaert M et al. | — | 2014 | → |
| Genetics of alcoholism. | Iyer-Eimerbrink PA et al. | — | 2014 | → |
| Global patterns of apparent copy number variation in birds revealed by cross-species comparative genomic hybridization. | Skinner BM et al. | — | 2014 | → |
| Haptoglobin (HP) and Haptoglobin-related protein (HPR) copy number variation, natural selection, and trypanosomiasis. | Hardwick RJ et al. | — | 2014 | → |
| Human gene copy number variation and infectious disease. | Hollox EJ et al. | — | 2014 | → |
| Identification of structural variation in mouse genomes. | Keane TM et al. | — | 2014 | → |
| Impact of diet on human intestinal microbiota and health. | Salonen A et al. | — | 2014 | → |
| Lactase persistence and augmented salivary alpha-amylase gene copy numbers might have been selected by the combined toxic effects of gluten and (food born) pathogens. | Pruimboom L et al. | — | 2014 | → |
| Low copy number of the salivary amylase gene predisposes to obesity. | Falchi M et al. | — | 2014 | → |
| New genes contribute to genetic and phenotypic novelties in human evolution. | Zhang YE et al. | — | 2014 | → |
| Of monkeys and men: a metabolomic analysis of static and dynamic urinary metabolic phenotypes in two species. | Saccenti E et al. | — | 2014 | → |
| Parallel developmental genetic features underlie stickleback gill raker evolution. | Glazer AM et al. | — | 2014 | → |
| Private haplotypes can reveal local adaptation. | Sjöstrand AE et al. | — | 2014 | → |
| Reliable quantification of protein expression and cellular localization in histological sections. | Schlederer M et al. | — | 2014 | → |
| Seasonal variation of urinary microRNA expression in male goats (Capra hircus) as assessed by next generation sequencing. | Longpre KM et al. | — | 2014 | → |
| Sequence and expression of an α-amylase gene in four related species of prickleback fishes (Teleostei: Stichaeidae): ontogenetic, dietary, and species-level effects. | Kim KH et al. | — | 2014 | → |
| Tandem amplification of a chromosomal segment harboring 5-enolpyruvylshikimate-3-phosphate synthase locus confers glyphosate resistance in Kochia scoparia. | Jugulam M et al. | — | 2014 | → |
| The human condition-a molecular approach. | Pääbo S | — | 2014 | → |
| The role of microhomology in genomic structural variation. | Ottaviani D et al. | — | 2014 | → |
| Transgenic expression of salmon delta-5 and delta-6 desaturase in zebrafish muscle inhibits the growth of Vibrio alginolyticus and affects fish immunomodulatory activity. | Wang YD et al. | — | 2014 | → |
| Transient and permanent experience with fatty acids changes Drosophila melanogaster preference and fitness. | Flaven-Pouchon J et al. | — | 2014 | → |
| Variation in salivary and pancreatic alpha-amylase genes in Italian horse breeds. | Coizet B et al. | — | 2014 | → |
| ABCs of genomics. | Bohlander SK | — | 2013 | → |
| Adaptation of the osmotolerant yeast Zygosaccharomyces rouxii to an osmotic environment through copy number amplification of FLO11D. | Watanabe J et al. | — | 2013 | → |
| An evolutionary perspective on food and human taste. | Breslin PA | — | 2013 | → |
| Beyond the Paleolithic prescription: incorporating diversity and flexibility in the study of human diet evolution. | Turner BL et al. | — | 2013 | → |
| Both positive and negative selection pressures contribute to the polymorphism pattern of the duplicated human CYP21A2 gene. | Szabó JA et al. | — | 2013 | → |
| Child development and structural variation in the human genome. | Zhang Y et al. | — | 2013 | → |
| Comparative digestive physiology. | Karasov WH et al. | — | 2013 | → |
| Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. | Watson CT et al. | — | 2013 | → |
| Continuing difficulties in interpreting CNV data: lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients. | Talseth-Palmer BA et al. | — | 2013 | → |
| Copy-number changes in evolution: rates, fitness effects and adaptive significance. | Katju V et al. | — | 2013 | → |
| Copy number variations of MICAL-L2 shaping gene expression contribute to different phenotypes of cattle. | Xu Y et al. | — | 2013 | → |
| Correlating multiallelic copy number polymorphisms with disease susceptibility. | Cantsilieris S et al. | — | 2013 | → |
| Detecting highly differentiated copy-number variants from pooled population sequencing. | Schrider DR et al. | — | 2013 | → |
| Detecting natural selection in genomic data. | Vitti JJ et al. | — | 2013 | → |
| Detecting negative selection on recurrent mutations using gene genealogy. | Ezawa K et al. | — | 2013 | → |
| Determination of genomic copy number alteration emphasizing a restriction site-based strategy of genome re-sequencing. | Zheng C et al. | — | 2013 | → |
| Do polymorphisms in chemosensory genes matter for human ingestive behavior? | Hayes JE et al. | — | 2013 | → |
| Do polymorphisms in the TAS1R1 gene contribute to broader differences in human taste intensity? | Rawal S et al. | — | 2013 | → |
| Evolutionary dynamics of copy number variation in pig genomes in the context of adaptation and domestication. | Paudel Y et al. | — | 2013 | → |
| Evolutionary genomics: Detecting selection. | Barsh GS et al. | — | 2013 | → |
| Genome-wide patterns of standing genetic variation in a marine population of three-spined sticklebacks. | Feulner PG et al. | — | 2013 | → |
| Glycaemic responses to glucose and rice in people of Chinese and European ethnicity. | Kataoka M et al. | — | 2013 | → |
| Hard selective sweep and ectopic gene conversion in a gene cluster affording environmental adaptation. | Hanikenne M et al. | — | 2013 | → |
| Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes. | Kanthaswamy S et al. | — | 2013 | → |
| Impact of constitutional copy number variants on biological pathway evolution. | Poptsova M et al. | — | 2013 | → |
| Impacts of variation in the human genome on gene regulation. | Haraksingh RR et al. | — | 2013 | → |
| Infrared spectroscopy with heated attenuated total internal reflectance enabling precise measurement of thermally induced transitions in complex biological polymers. | Warren FJ et al. | — | 2013 | → |
| Male infertility and copy number variants (CNVs) in the dog: a two-pronged approach using Computer Assisted Sperm Analysis (CASA) and Fluorescent In Situ Hybridization (FISH). | Cassatella D et al. | — | 2013 | → |
| Measurements of salivary alpha amylase and salivary cortisol in hominoid primates reveal within-species consistency and between-species differences. | Behringer V et al. | — | 2013 | → |
| MiR-23a in amplified 19p13.13 loci targets metallothionein 2A and promotes growth in gastric cancer cells. | An J et al. | — | 2013 | → |
| Molecular methods for genotyping complex copy number polymorphisms. | Cantsilieris S et al. | — | 2013 | → |
| Neofunctionalization of young duplicate genes in Drosophila. | Assis R et al. | — | 2013 | → |
| Peregrine and saker falcon genome sequences provide insights into evolution of a predatory lifestyle. | Zhan X et al. | — | 2013 | → |
| Personality factors predict spicy food liking and intake. | Byrnes NK et al. | — | 2013 | → |
| Phenotypic impact of genomic structural variation: insights from and for human disease. | Weischenfeldt J et al. | — | 2013 | → |
| Possible positive selection for an arsenic-protective haplotype in humans. | Schlebusch CM et al. | — | 2013 | → |
| Preliminary insights into the impact of dietary starch on the ciliate, Neobalantidium coli, in captive chimpanzees. | Schovancová K et al. | — | 2013 | → |
| Prevalence of selected genomic deletions and duplications in a French-Canadian population-based sample of newborns. | Tucker T et al. | — | 2013 | → |
| Primate genome architecture influences structural variation mechanisms and functional consequences. | Gokcumen O et al. | — | 2013 | → |
| Rates and genomic consequences of spontaneous mutational events in Drosophila melanogaster. | Schrider DR et al. | — | 2013 | → |
| Selection and adaptation in the human genome. | Fu W et al. | — | 2013 | → |
| The genetic causes of convergent evolution. | Stern DL | — | 2013 | → |
| The genome-wide landscape of copy number variations in the MUSGEN study provides evidence for a founder effect in the isolated Finnish population. | Kanduri C et al. | — | 2013 | → |
| The genomic signature of dog domestication reveals adaptation to a starch-rich diet. | Axelsson E et al. | — | 2013 | → |
| The impact of natural selection on health and disease: uses of the population genetics approach in humans. | Vasseur E et al. | — | 2013 | → |
| The Loci of repeated evolution: a catalog of genetic hotspots of phenotypic variation. | Martin A et al. | — | 2013 | → |
| The Role of Copy Number Variation in African Americans with Type 2 Diabetes-Associated End Stage Renal Disease. | Bailey JN et al. | — | 2013 | → |
| Time-resolved in-situ observation of starch polysaccharide degradation pathways. | Beeren SR et al. | — | 2013 | → |
| Turning over a new leaf in plant genomics. | Caccamo M et al. | — | 2013 | → |
| Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection. | Chang CL et al. | — | 2013 | → |
| Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders. | Bassaganyas L et al. | — | 2013 | → |
| Amylase gene expression patterns in Helicoverpa armigera upon feeding on a range of host plants. | Kotkar HM et al. | — | 2012 | → |
| An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals. | Münk C et al. | — | 2012 | → |
| An integrated biochemistry and genetics outreach program designed for elementary school students. | Ross ED et al. | — | 2012 | → |
| Attention-deficit/hyperactivity disorder genomics: update for clinicians. | Elia J et al. | — | 2012 | → |
| Brains have a gut feeling about fat storage: an overall inverse correlation between fat deposits and brain size in mammals is explained by neurons not burning fat. | Speijer D | — | 2012 | → |
| Carbohydrate intake. | Leturque A et al. | — | 2012 | → |
| Characterization of the activity and stability of amylase from saliva and detergent: laboratory practicals for studying the activity and stability of amylase from saliva and various commercial detergents. | Valls C et al. | — | 2012 | → |
| CNVs leading to fusion transcripts in individuals with autism spectrum disorder. | Holt R et al. | — | 2012 | → |
| Copy number polymorphism of the salivary amylase gene: implications in human nutrition research. | Santos JL et al. | — | 2012 | → |
| Copy number variation in the genomes of domestic animals. | Clop A et al. | — | 2012 | → |
| Copy number variation of multiple genes at Rhg1 mediates nematode resistance in soybean. | Cook DE et al. | — | 2012 | → |
| Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. | Lin P et al. | — | 2012 | → |
| Copy-number variations observed in a Japanese population by BAC array CGH: summary of relatively rare CNVs. | Satoh Y et al. | — | 2012 | → |
| Cutting-edge issues in primary biliary cirrhosis. | Folci M et al. | — | 2012 | → |
| Dental microwear and stable isotopes inform the paleoecology of extinct hominins. | Grine FE et al. | — | 2012 | → |
| Dental microwear texture and anthropoid diets. | Scott RS et al. | — | 2012 | → |
| Depression as a disease of modernity: explanations for increasing prevalence. | Hidaka BH | — | 2012 | → |
| Determining the evolutionary history of gene families. | Ames RM et al. | — | 2012 | → |
| Development of multilocus putatively neutral DNA markers in the X-chromosome for population genetic studies in humans. | Khan N et al. | — | 2012 | → |
| Dosage compensation of the sex chromosomes. | Disteche CM | — | 2012 | → |
| Evolutionary genetics of the human Rh blood group system. | Perry GH et al. | — | 2012 | → |
| Exploring the role of copy number variants in human adaptation. | Iskow RC et al. | — | 2012 | → |
| Extensive and continuous duplication facilitates rapid evolution and diversification of gene families. | Chang D et al. | — | 2012 | → |
| Fundamentals of nutrigenetics and nutrigenomics. | Bouchard C et al. | — | 2012 | → |
| Gene copy number variation and its significance in cyanobacterial phylogeny. | Schirrmeister BE et al. | — | 2012 | → |
| Gene duplication as a mechanism of genomic adaptation to a changing environment. | Kondrashov FA | — | 2012 | → |
| Genetic explorations of recent human metabolic adaptations: hypotheses and evidence. | Brown EA | — | 2012 | → |
| Genome patterns of selection and introgression of haplotypes in natural populations of the house mouse (Mus musculus). | Staubach F et al. | — | 2012 | → |
| Genome-wide copy number analysis of single cells. | Baslan T et al. | — | 2012 | → |
| Genomic structure and evolution of multigene families: "flowers" on the human genome. | Kim HL et al. | — | 2012 | → |
| High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults. | Mandel AL et al. | — | 2012 | → |
| High-resolution fish on DNA fibers for low-copy repeats genome architecture studies. | Molina O et al. | — | 2012 | → |
| Human genome sequencing in health and disease. | Gonzaga-Jauregui C et al. | — | 2012 | → |
| Identification of functional CNV region networks using a CNV-gene mapping algorithm in a genome-wide scale. | Park C et al. | — | 2012 | → |
| Implications of gene copy-number variation in health and diseases. | Almal SH et al. | — | 2012 | → |
| Increased genome sampling reveals a dynamic relationship between gene duplicability and the structure of the primate protein-protein interaction network. | Doherty A et al. | — | 2012 | → |
| Invasion of gene duplication through masking for maladaptive gene flow. | Yanchukov A et al. | — | 2012 | → |
| Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum. | Jain V et al. | — | 2012 | → |
| Mutation spectrum of Drosophila CNVs revealed by breakpoint sequencing. | Cardoso-Moreira M et al. | — | 2012 | → |
| Neanderthal medics? Evidence for food, cooking, and medicinal plants entrapped in dental calculus. | Hardy K et al. | — | 2012 | → |
| New genes expressed in human brains: implications for annotating evolving genomes. | Zhang YE et al. | — | 2012 | → |
| Novel origins of copy number variation in the dog genome. | Berglund J et al. | — | 2012 | → |
| Nutrigenomics and Cancer Prevention. | Nicastro HL et al. | — | 2012 | → |
| Paleolithic diets as a model for prevention and treatment of Western disease. | Lindeberg S | — | 2012 | → |
| Reducing system noise in copy number data using principal components of self-self hybridizations. | Lee YH et al. | — | 2012 | → |
| Saliva proteomics as an emerging, non-invasive tool to study livestock physiology, nutrition and diseases. | Lamy E et al. | — | 2012 | → |
| Selection for adaptation to dietary shifts: towards sustainable breeding of carnivorous fish. | Le Boucher R et al. | — | 2012 | → |
| Spectrum of large copy number variations in 26 diverse Indian populations: potential involvement in phenotypic diversity. | Gautam P et al. | — | 2012 | → |
| Stress affects salivary alpha-Amylase activity in bonobos. | Behringer V et al. | — | 2012 | → |
| Structural variants in the soybean genome localize to clusters of biotic stress-response genes. | McHale LK et al. | — | 2012 | → |
| Surface thermodynamic homeostasis of salivary conditioning films through polar-apolar layering. | van der Mei HC et al. | — | 2012 | → |
| The coalescent with selection on copy number variants. | Teshima KM et al. | — | 2012 | → |
| The effect of low- and high-fiber diets on the population of entodiniomorphid ciliates Troglodytella abrassarti in captive chimpanzees (Pan troglodytes). | Petrželková KJ et al. | — | 2012 | → |
| The hypothesis on function of glycosphingolipids and ABO blood groups revisited. | Kościelak J | — | 2012 | → |
| The relationship between gut microbiota and weight gain in humans. | Angelakis E et al. | — | 2012 | → |
| The scientific exploration of saliva in the post-proteomic era: from database back to basic function. | Ruhl S | — | 2012 | → |
| Variability of human saliva composition: possible relationships with fat perception and liking. | Neyraud E et al. | — | 2012 | → |
| Virus population bottlenecks during within-host progression and host-to-host transmission. | Gutiérrez S et al. | — | 2012 | → |
| Adaptations to climate-mediated selective pressures in humans. | Hancock AM et al. | — | 2011 | → |
| Adaptive selection of an incretin gene in Eurasian populations. | Chang CL et al. | — | 2011 | → |
| Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey. | Sabbagh A et al. | — | 2011 | → |
| A worldwide analysis of beta-defensin copy number variation suggests recent selection of a high-expressing DEFB103 gene copy in East Asia. | Hardwick RJ et al. | — | 2011 | → |
| Classic selective sweeps were rare in recent human evolution. | Hernandez RD et al. | — | 2011 | → |
| Comparative genetic approaches to the evolution of human brain and behavior. | Vallender EJ | — | 2011 | → |
| Cooking clue to human dietary diversity. | Lucas PW | — | 2011 | → |
| Copy number alterations among mammalian enzymes cluster in the metabolic network. | Bekaert M et al. | — | 2011 | → |
| Copy number variation. | Wain LV et al. | — | 2011 | → |
| Copy number variation accuracy in genome-wide association studies. | Lin P et al. | — | 2011 | → |
| Copy number variation across European populations. | Chen W et al. | — | 2011 | → |
| Copy number variation and susceptibility to complex traits. | Canales CP et al. | — | 2011 | → |
| Copy number variation of microRNA genes in the human genome. | Marcinkowska M et al. | — | 2011 | → |
| Darwin in mind: new opportunities for evolutionary psychology. | Bolhuis JJ et al. | — | 2011 | → |
| Data-driven approach to detect common copy-number variations and frequency profiles in a population-based Korean cohort. | Moon S et al. | — | 2011 | → |
| Detection of copy number variation using SNP genotyping. | Cooper GM et al. | — | 2011 | → |
| Drosophila duplication hotspots are associated with late-replicating regions of the genome. | Cardoso-Moreira M et al. | — | 2011 | → |
| Ecological physiology of diet and digestive systems. | Karasov WH et al. | — | 2011 | → |
| Gene duplication and ectopic gene conversion in Drosophila. | Arguello JR et al. | — | 2011 | → |
| Genome structural variation discovery and genotyping. | Alkan C et al. | — | 2011 | → |
| Genomic signatures of diet-related shifts during human origins. | Babbitt CC et al. | — | 2011 | → |
| High spontaneous rate of gene duplication in Caenorhabditis elegans. | Lipinski KJ et al. | — | 2011 | → |
| Human nutrition, the gut microbiome and the immune system. | Kau AL et al. | — | 2011 | → |
| Identification of a genomic reservoir for new TRIM genes in primate genomes. | Han K et al. | — | 2011 | → |
| Independent duplications of α-amylase in different strains of Aspergillus oryzae. | Hunter AJ et al. | — | 2011 | → |
| In-mouth mechanisms leading to flavor release and perception. | Salles C et al. | — | 2011 | → |
| Inside the CBF locus in Poaceae. | Tondelli A et al. | — | 2011 | → |
| Linking genotypes, phenotypes, and fitness in wild primate populations. | Bradley BJ et al. | — | 2011 | → |
| Man the fat hunter: the demise of Homo erectus and the emergence of a new hominin lineage in the Middle Pleistocene (ca. 400 kyr) Levant. | Ben-Dor M et al. | — | 2011 | → |
| Microbial metabolomics. | Tang J | — | 2011 | → |
| Mobile DNA and the TE-Thrust hypothesis: supporting evidence from the primates. | Oliver KR et al. | — | 2011 | → |
| Natural alcohol exposure: is ethanol the main substrate for alcohol dehydrogenases in animals? | Hernández-Tobías A et al. | — | 2011 | → |
| Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice. | Fenech M et al. | — | 2011 | → |
| Positive selection shaped the convergent evolution of independently expanded kallikrein subfamilies expressed in mouse and rat saliva proteomes. | Karn RC et al. | — | 2011 | → |
| Rapid turnover of functional sequence in human and other genomes. | Ponting CP et al. | — | 2011 | → |
| Recent advances in understanding the role of nutrition in human genome evolution. | Ye K et al. | — | 2011 | → |
| Refinement of primate copy number variation hotspots identifies candidate genomic regions evolving under positive selection. | Gokcumen O et al. | — | 2011 | → |
| Review: starch matrices and the glycemic response. | Parada J et al. | — | 2011 | → |
| Runaway cultural niche construction. | Rendell L et al. | — | 2011 | → |
| State and trait variance in salivary α-amylase: a behavioral genetic study. | Out D et al. | — | 2011 | → |
| The human gut microbiome: ecology and recent evolutionary changes. | Walter J et al. | — | 2011 | → |
| To lyse or not to lyse: transient-mediated stochastic fate determination in cells infected by bacteriophages. | Joh RI et al. | — | 2011 | → |
| Two-phase resolution of polyploidy in the Arabidopsis metabolic network gives rise to relative and absolute dosage constraints. | Bekaert M et al. | — | 2011 | → |
| Variability in dental caries prevalence between male and female foragers from the Late/Final Jomon period: Implications for dietary behavior and reproductive ecology. | Temple DH | — | 2011 | → |
| A critical assessment of cross-species detection of gene duplicates using comparative genomic hybridization. | Machado HE et al. | — | 2010 | → |
| Adaptations to new environments in humans: the role of subtle allele frequency shifts. | Hancock AM et al. | — | 2010 | → |
| Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus. | Gresham D et al. | — | 2010 | → |
| Allelic genome structural variations in maize detected by array comparative genome hybridization. | Beló A et al. | — | 2010 | → |
| An expectation-maximization program for determining allelic spectrum from CNV data (CoNVEM): insights into population allelic architecture and its mutational history. | Gaunt TR et al. | — | 2010 | → |
| An initial map of chromosomal segmental copy number variations in the chicken. | Wang X et al. | — | 2010 | → |
| Are we Genomic Mosaics? Variations of the Genome of Somatic Cells can Contribute to Diversify our Phenotypes. | Astolfi PA et al. | — | 2010 | → |
| Carbohydrate metabolic pathway genes associated with quantitative trait loci (QTL) for obesity and type 2 diabetes: identification by data mining. | Varma V et al. | — | 2010 | → |
| CBF gene copy number variation at Frost Resistance-2 is associated with levels of freezing tolerance in temperate-climate cereals. | Knox AK et al. | — | 2010 | → |
| Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm. | Al-Ahmad A et al. | — | 2010 | → |
| Changes in mouse whole saliva soluble proteome induced by tannin-enriched diet. | Lamy E et al. | — | 2010 | → |
| Colloquium paper: gene-culture coevolution in the age of genomics. | Richerson PJ et al. | — | 2010 | → |
| Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. | Hancock AM et al. | — | 2010 | → |
| Complete Khoisan and Bantu genomes from southern Africa. | Schuster SC et al. | — | 2010 | → |
| Connecting the Human Variome Project to nutrigenomics. | Kaput J et al. | — | 2010 | → |
| Contrasting modes of evolution of the visual pigments in Heliconius butterflies. | Yuan F et al. | — | 2010 | → |
| Copy number changes of CNV regions in intersubspecific crosses of the house mouse. | Scavetta RJ et al. | — | 2010 | → |
| Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution. | Völker M et al. | — | 2010 | → |
| Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease. | Colobran R et al. | — | 2010 | → |
| Copy number variation in the bovine genome. | Fadista J et al. | — | 2010 | → |
| Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease. | Zhou XJ et al. | — | 2010 | → |
| Dating and functional characterization of duplicated genes in the apple (Malus domestica Borkh.) by analyzing EST data. | Sanzol J | — | 2010 | → |
| Detecting simultaneous changepoints in multiple sequences. | Zhang NR et al. | — | 2010 | → |
| Detecting structural variations in the human genome using next generation sequencing. | Xi R et al. | — | 2010 | → |
| Did gene family expansions during the Eocene-Oligocene boundary climate cooling play a role in Pooideae adaptation to cool climates? | Sandve SR et al. | — | 2010 | → |
| Diversity: Of beans and genes. | Eisenstein M | — | 2010 | → |
| Evolutionary adaptations to dietary changes. | Luca F et al. | — | 2010 | → |
| Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution. | Carvalho CM et al. | — | 2010 | → |
| Evolution of detoxifying systems: the role of environment and population history in shaping genetic diversity at human CYP2D6 locus. | Fuselli S et al. | — | 2010 | → |
| Gene copy-number polymorphism in nature. | Schrider DR et al. | — | 2010 | → |
| How culture shaped the human genome: bringing genetics and the human sciences together. | Laland KN et al. | — | 2010 | → |
| Identification and frequency estimation of inversion polymorphisms from haplotype data. | Sindi SS et al. | — | 2010 | → |
| Identification of novel gastric cancer-associated CNVs by integrated analysis of microarray. | Park CH et al. | — | 2010 | → |
| Indication of higher salivary alpha-amylase expression in hamadryas baboons and geladas compared to chimpanzees and humans. | Mau M et al. | — | 2010 | → |
| Individual differences in AMY1 gene copy number, salivary α-amylase levels, and the perception of oral starch. | Mandel AL et al. | — | 2010 | → |
| Intestinal fermentation in patients with self-reported food hypersensitivity: painful, but protective? | Valeur J et al. | — | 2010 | → |
| Lineage-specific duplication and loss of pepsinogen genes in hominoid evolution. | Narita Y et al. | — | 2010 | → |
| Lower linkage disequilibrium at CNVs is due to both recurrent mutation and transposing duplications. | Schrider DR et al. | — | 2010 | → |
| Measuring selection in contemporary human populations. | Stearns SC et al. | — | 2010 | → |
| Molecular adaptation of modern human populations. | Shi H et al. | — | 2010 | → |
| Mutational bias shaping fly copy number variation: implications for genome evolution. | Cardoso-Moreira MM et al. | — | 2010 | → |
| Mutational effects and the evolution of new protein functions. | Soskine M et al. | — | 2010 | → |
| Nature and nurture in neuropsychiatric genetics: where do we stand? | Dick DM et al. | — | 2010 | → |
| Nonadaptive processes in primate and human evolution. | Harris EE | — | 2010 | → |
| Nutritional genomics era: opportunities toward a genome-tailored nutritional regimen. | Costa V et al. | — | 2010 | → |
| Our unindicted coconspirators: human metabolism from a microbial perspective. | Goodman AL et al. | — | 2010 | → |
| Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models. | Ricard G et al. | — | 2010 | → |
| Plant foods consumed by Pan: exploring the variation of nutritional ecology across Africa. | Hohmann G et al. | — | 2010 | → |
| Population-genetic nature of copy number variations in the human genome. | Kato M et al. | — | 2010 | → |
| RNA-mediated epigenetic regulation of DNA copy number. | Nowacki M et al. | — | 2010 | → |
| The ADH1B Arg47His polymorphism in east Asian populations and expansion of rice domestication in history. | Peng Y et al. | — | 2010 | → |
| The evolutionary fate of the genes encoding the purine catabolic enzymes in hominoids, birds, and reptiles. | Keebaugh AC et al. | — | 2010 | → |
| The evolution of gene duplications: classifying and distinguishing between models. | Innan H et al. | — | 2010 | → |
| The evolution of human genetic and phenotypic variation in Africa. | Campbell MC et al. | — | 2010 | → |
| The relationship among gene expression, the evolution of gene dosage, and the rate of protein evolution. | Gout JF et al. | — | 2010 | → |
| Towards population genomics of effector-effector target interactions. | Terauchi R et al. | — | 2010 | → |
| Using oral microbial DNA analysis to identify expirated bloodspatter. | Donaldson AE et al. | — | 2010 | → |
| A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. | Lin CH et al. | — | 2009 | → |
| Allelic recombination between distinct genomic locations generates copy number diversity in human beta-defensins. | Abu Bakar S et al. | — | 2009 | → |
| Amylase. | Reynolds TM | — | 2009 | → |
| A profound role for the expansion of trypsin-like serine protease family in the evolution of hematophagy in mosquito. | Wu DD et al. | — | 2009 | → |
| Better outcome of schizophrenia in India: a natural selection against severe forms? | Thirthalli J et al. | — | 2009 | → |
| Challenges for CNV interpretation in clinical molecular karyotyping: lessons learned from a 1001 sample experience. | Buysse K et al. | — | 2009 | → |
| Comparative genomic hybridization: microarray design and data interpretation. | Redon R et al. | — | 2009 | → |
| Copy number variants (CNVs) in primate species using array-based comparative genomic hybridization. | Gökçümen O et al. | — | 2009 | → |
| Copy number variants, diseases and gene expression. | Henrichsen CN et al. | — | 2009 | → |
| Copy number variation in human health, disease, and evolution. | Zhang F et al. | — | 2009 | → |
| Copy number variation in the human genome and its implication in autoimmunity. | Schaschl H et al. | — | 2009 | → |
| Determinants of salivary alpha-amylase in humans and methodological considerations. | Rohleder N et al. | — | 2009 | → |
| Distinguishing among evolutionary models for the maintenance of gene duplicates. | Hahn MW | — | 2009 | → |
| Evolutionary genetics as a tool to target genes involved in phenotypes of medical relevance. | Heyer E et al. | — | 2009 | → |
| Evolutionary history reconstruction for Mammalian complex gene clusters. | Zhang Y et al. | — | 2009 | → |
| Gene copy number and malaria biology. | Anderson TJ et al. | — | 2009 | → |
| Genetic association analysis of copy-number variation (CNV) in human disease pathogenesis. | Ionita-Laza I et al. | — | 2009 | → |
| Genome-wide association studies and the genetic dissection of complex traits. | Sebastiani P et al. | — | 2009 | → |
| Genomic copy number variation, human health, and disease. | Wain LV et al. | — | 2009 | → |
| Glycoprofiling of the Human Salivary Proteome. | Sondej M et al. | — | 2009 | → |
| Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: a comparison of Asian-Indian and European American populations. | Saxena K et al. | — | 2009 | → |
| Industrial fuel ethanol yeasts contain adaptive copy number changes in genes involved in vitamin B1 and B6 biosynthesis. | Stambuk BU et al. | — | 2009 | → |
| Inter-individual variability of protein patterns in saliva of healthy adults. | Quintana M et al. | — | 2009 | → |
| Intraspecific variation of the crotamine and crotasin genes in Crotalus durissus rattlesnakes. | Oguiura N et al. | — | 2009 | → |
| Linking genotypes to phenotypes and fitness: how mechanistic biology can inform molecular ecology. | Dalziel AC et al. | — | 2009 | → |
| Mapping duplicated sequences. | Chiang DY et al. | — | 2009 | → |
| Mechanisms of change in gene copy number. | Hastings PJ et al. | — | 2009 | → |
| Microarray-based comparative genomic hybridization using sex-matched reference DNA provides greater sensitivity for detection of sex chromosome imbalances than array-comparative genomic hybridization with sex-mismatched reference DNA. | Yatsenko SA et al. | — | 2009 | → |
| PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data. | Korbel JO et al. | — | 2009 | → |
| Planning the human variome project: the Spain report. | Kaput J et al. | — | 2009 | → |
| Scanning for the signatures of positive selection for human-specific insertions and deletions. | Chen CH et al. | — | 2009 | → |
| Segmental copy number variation shapes tissue transcriptomes. | Henrichsen CN et al. | — | 2009 | → |
| Signals of recent positive selection in a worldwide sample of human populations. | Pickrell JK et al. | — | 2009 | → |
| Spatial patterns of variation due to natural selection in humans. | Novembre J et al. | — | 2009 | → |
| The glycaemic index values of foods containing fructose are affected by metabolic differences between subjects. | Wolever TM et al. | — | 2009 | → |
| The importance of a genetic component in longitudinal birth cohorts. | Golding J | — | 2009 | → |
| The role of geography in human adaptation. | Coop G et al. | — | 2009 | → |
| The second green revolution? Production of plant-based biodegradable plastics. | Mooney BP | — | 2009 | → |
| The year in human and medical genetics. Highlights of 2007-2008. | Smith M | — | 2009 | → |
| Adaptive copy number evolution in malaria parasites. | Nair S et al. | — | 2008 | → |
| Adaptive evolution of UGT2B17 copy-number variation. | Xue Y et al. | — | 2008 | → |
| African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. | Campbell MC et al. | — | 2008 | → |
| A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan. | Lin CH et al. | — | 2008 | → |
| Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. | Lee AS et al. | — | 2008 | → |
| Analysis of the largest tandemly repeated DNA families in the human genome. | Warburton PE et al. | — | 2008 | → |
| Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds. | Bosch N et al. | — | 2008 | → |
| A novel mechanistic spectrum underlies glaucoma-associated chromosome 6p25 copy number variation. | Chanda B et al. | — | 2008 | → |
| Comparing whole genomes using DNA microarrays. | Gresham D et al. | — | 2008 | → |
| Complex genetics of obesity in mouse models. | Pomp D et al. | — | 2008 | → |
| Copy-number analysis goes more than skin deep. | McCarroll SA | — | 2008 | → |
| Copy number variant analysis of human embryonic stem cells. | Wu H et al. | — | 2008 | → |
| Defensins and the dynamic genome: what we can learn from structural variation at human chromosome band 8p23.1. | Hollox EJ et al. | — | 2008 | → |
| Detecting the Genetic Signature of Natural Selection in Human Populations: Models, Methods, and Data. | Hancock AM et al. | — | 2008 | → |
| Explaining human uniqueness: genome interactions with environment, behaviour and culture. | Varki A et al. | — | 2008 | → |
| Extensive copy-number variation of the human olfactory receptor gene family. | Young JM et al. | — | 2008 | → |
| Gene dosage and gene duplicability. | Qian W et al. | — | 2008 | → |
| Genetic determinants of phenotypic diversity in humans. | Rahim NG et al. | — | 2008 | → |
| Genomic analysis of differentiation between soil types reveals candidate genes for local adaptation in Arabidopsis lyrata. | Turner TL et al. | — | 2008 | → |
| Great apes prefer cooked food. | Wobber V et al. | — | 2008 | → |
| Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation. | Masson E et al. | — | 2008 | → |
| Human and chimpanzee gene expression differences replicated in mice fed different diets. | Somel M et al. | — | 2008 | → |
| Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease. | de Smith AJ et al. | — | 2008 | → |
| Improved detection of global copy number variation using high density, non-polymorphic oligonucleotide probes. | Shen F et al. | — | 2008 | → |
| Integrated detection and population-genetic analysis of SNPs and copy number variation. | McCarroll SA et al. | — | 2008 | → |
| Multiple advantageous amino acid variants in the NAT2 gene in human populations. | Luca F et al. | — | 2008 | → |
| New applications and developments in the use of multiplex ligation-dependent probe amplification. | Kozlowski P et al. | — | 2008 | → |
| Nutrigenomics research for personalized nutrition and medicine. | Kaput J | — | 2008 | → |
| Nutrition and cancer: essential elements for a roadmap. | Milner JA | — | 2008 | → |
| Patterns of positive selection in six Mammalian genomes. | Kosiol C et al. | — | 2008 | → |
| Positive selection in the human genome: from genome scans to biological significance. | Kelley JL et al. | — | 2008 | → |
| Reduced purifying selection prevails over positive selection in human copy number variant evolution. | Nguyen DQ et al. | — | 2008 | → |
| Small-scale copy number variation and large-scale changes in gene expression. | Mileyko Y et al. | — | 2008 | → |
| Systematic assessment of copy number variant detection via genome-wide SNP genotyping. | Cooper GM et al. | — | 2008 | → |
| The current excitement about copy-number variation: how it relates to gene duplications and protein families. | Korbel JO et al. | — | 2008 | → |
| The evolutionary significance of copy number variation in the human genome. | Perry GH | — | 2008 | → |
| The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity. | Nei M et al. | — | 2008 | → |
| The fine-scale and complex architecture of human copy-number variation. | Perry GH et al. | — | 2008 | → |
| The functional impact of structural variation in humans. | Hurles ME et al. | — | 2008 | → |
| The genome: you gain some, you lose some. | Breuning MH | — | 2008 | → |
| The loci of evolution: how predictable is genetic evolution? | Stern DL et al. | — | 2008 | → |
| Worlds within worlds: evolution of the vertebrate gut microbiota. | Ley RE et al. | — | 2008 | → |
| Adaptive drool in the gene pool. | Novembre J et al. | — | 2007 | → |
| An evolution revolution provides further revelation. | Lupski JR | — | 2007 | → |
| A portrait of copy-number polymorphism in Drosophila melanogaster. | Dopman EB et al. | — | 2007 | → |
| Evolution of protein expression: new genes for a new diet. | Coyne JA et al. | — | 2007 | → |
| So similar, yet so different. | Check Hayden E | — | 2007 | → |
| The drifting human genome. | Zhang J | — | 2007 | → |