Neurophysiological factors in individuals at risk for alcoholism.
- Authors
- Porjesz, B; Begleiter, H
- Year
- 1991
- Journal
- Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
- PMID
- 1758994
The literature dealing with electrophysiological research in individuals at risk for alcoholism is reviewed. Event-related potential (ERP) and electroencephalographic (EEG) differences between family-history-positive (FHP) and family-history-negative (FHN) men have been reported both prior to the ingestion of alcohol and following alcohol challenge doses. At present, the most robust of these electrophysiological findings is the lower P3 amplitude of the ERP, which has now been replicated in several laboratories. This perhaps provides a phenotypic marker, distinguishing those at risk for alcoholism. However, its specificity for alcoholism and the role of gene-environment interactions in the development of alcoholism remain to be determined.
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In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Prediction of brain age in individuals with and at risk for alcohol use disorder using brain morphological features | Kamarajan C et al. | — | 2024 | — |
| Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats. | Froehlich JC et al. | — | 2017 | → |
| Advances in Electrophysiological Research. | Kamarajan C et al. | — | 2015 | → |
| Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. | Kamarajan C et al. | — | 2015 | → |
| Genetic psychophysiology: advances, problems, and future directions. | Anokhin AP | — | 2014 | → |
| Neurocognitive deficits in male alcoholics: an ERP/sLORETA analysis of the N2 component in an equal probability Go/NoGo task. | Pandey AK et al. | — | 2012 | → |
| Effects of adolescent ethanol exposure on event-related oscillations (EROs) in the hippocampus of adult rats. | Criado JR et al. | — | 2010 | → |
| Effects of adolescent ethanol exposure on sleep in adult rats. | Criado JR et al. | — | 2008 | → |
| Electrophysiological effects of dizocilpine (MK-801) in adult rats exposed to ethanol during adolescence. | Criado JR et al. | — | 2008 | → |
| Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism. | Kamarajan C et al. | — | 2006 | → |
| Visual P300s in long-term abstinent chronic alcoholics. | Fein G et al. | — | 2006 | → |
| Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task. | Kamarajan C et al. | — | 2005 | → |
| Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism. | Kamarajan C et al. | — | 2005 | → |
| Functional magnetic resonance imaging of brain activity in the visual oddball task. | Ardekani BA et al. | — | 2002 | → |
| Determination of biological markers for alcohol abuse. | Musshoff F et al. | — | 1998 | → |