An overview of the genetics of substance use disorders.
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Cited
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- Authors
- Lachman, H M
- Year
- 2006
- Journal
- Current psychiatry reports
- PMID
- 16539891
- DOI
- 10.1007/s11920-006-0013-3
Twin, family, and adoption studies show that genetic factors play a significant role in vulnerability to becoming addicted to drugs. Through a combination of genetic approaches, the variant alleles responsible for interindividual differences in susceptibility to addiction are being uncovered.
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| Title | Year | PMID |
|---|---|---|
| The genetics of substance dependence. | 2012 | 22703173 |
External
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| Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction. | Mehić-Basara N et al. | — | 2013 | → |
| Genetic differences in the modulation of accumbal glutamate and γ-amino butyric acid levels after cocaine-induced reinstatement. | Miguéns M et al. | — | 2013 | → |
| Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats. | Picetti R et al. | — | 2012 | → |
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| Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses. | Zhang H et al. | — | 2012 | → |
| Depotentiation of hippocampal long-term potentiation depends on genetic background and is modulated by cocaine self-administration. | Miguéns M et al. | — | 2011 | → |
| Association analysis between polymorphisms in the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes with cocaine dependence. | Lohoff FW et al. | — | 2010 | → |
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| Genomewide suggestive linkage of opioid dependence to chromosome 14q. | Lachman HM et al. | — | 2007 | → |
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| Modulation of the endogenous opioid system after morphine self-administration and during its extinction: a study in Lewis and Fischer 344 rats. | Sánchez-Cardoso P et al. | — | 2007 | → |