The relationship between smoking and suicidal behavior, comorbidity, and course of illness in bipolar disorder.
paper
Cited
Public
Unavailable
- Authors
- Ostacher, Michael J; Nierenberg, Andrew A; Perlis, Roy H; Eidelman, Polina; Borrelli, David J; Tran, Tanya B; Marzilli Ericson, Gianna; Weiss, Roger D; Sachs, Gary S
- Year
- 2006
- Journal
- The Journal of clinical psychiatry
- PMID
- 17194268
- DOI
- 10.4088/jcp.v67n1210
OBJECTIVES: The rate of smoking in people with bipolar disorder is much greater than in the general population, but the implications of smoking for the course of bipolar disorder have not been well studied. The purpose of this retrospective study was to examine the relationship between smoking, severity of bipolar disorder, suicidal behavior, and psychiatric and substance use disorder comorbidity. METHOD: We evaluated 399 outpatients with bipolar disorder who were treated in a bipolar specialty clinic from December 1999 to October 2004. Diagnosis, mood state, course of illness, functioning, and psychiatric comorbidities were assessed using the Affective Disorders Evaluation and the Mini-International Neuropsychiatric Interview. RESULTS: Of the 399 patients evaluated, 155 (38.8%) had a history of daily smoking. Having ever smoked was associated with earlier age at onset of first depressive or manic episode, lower Global Assessment of Functioning scores, higher Clinical Global Impressions-Bipolar Disorder scale scores, lifetime history of a suicide attempt (47% for smokers vs. 25% for those who had never smoked), and lifetime comorbid disorders: anxiety disorders, alcohol abuse and dependence, and substance abuse and dependence. In a logistic regression model including these factors, suicide attempts and substance dependence were significantly associated with smoking in patients with bipolar disorder. CONCLUSIONS: Bipolar patients with lifetime smoking were more likely to have earlier age at onset of mood disorder, greater severity of symptoms, poorer functioning, history of a suicide attempt, and a lifetime history of comorbid anxiety and substance use disorders. Smoking may be independently associated with suicidal behavior in bipolar disorder.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Genetics of addictions. | 2010 | 20159342 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Bipolar Disorder Hospitalizations and Substance Use Disorders: A Nationwide Retrospective Study From 2008 To 2015. | Valente L et al. | β | 2025 | β |
| Cannabis and tobacco use in bipolar disorder: Associations with early onset, psychotic symptoms, and relapse risk (2015-2019). | Olivier L et al. | β | 2025 | β |
| "Everybody's problem but nobody's problem": Qualitative study on integrating smoking cessation and mental health services in Singapore. | Lok YL et al. | β | 2025 | β |
| Lifestyle factors, metabolic syndrome and apolipoprotein E in monozygotic twins with, at risk of and without affective disorders, as predictors of onset or recurrence of affective episodes, a seven-years follow-up study. | Vinberg M et al. | β | 2025 | β |
| Relationship Between Smoking and Psychiatric and Somatic Comorbidities in Older Age Bipolar Disorder: Lien entre le tabagisme et les affections psychiatriques et somatiques concomitantes chez les personnes Γ’gΓ©es atteintes de trouble bipolaire. | Howland M et al. | β | 2025 | β |
| Smoking behavior is associated with suicidality in individuals with psychosis and bipolar disorder: a systematic quantitative review and meta-analysis. | Pietschnig J et al. | β | 2024 | β |
| Cigarette smoking and risk of suicide in bipolar disorder: a systematic review. | GarcΓa-JimΓ©nez J et al. | β | 2023 | β |
| The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management. | McIntyre RS et al. | β | 2022 | β |
| The detrimental effects of smoking on the course and outcome in adults with bipolar disorder-A narrative review. | Grunze A et al. | β | 2022 | β |
| Cigarette Smoking in an Acute Partial Hospital Program. | Guggenheim FG et al. | β | 2021 | β |
| Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study. | Vermeulen JM et al. | β | 2021 | β |
| A study on tobacco use in women with major mental illnesses- schizophrenia, bipolar disorder and recurrent depression. | Khobragade B et al. | β | 2020 | β |
| Call to action regarding the vascular-bipolar link: A report from the Vascular Task Force of the International Society for Bipolar Disorders. | Goldstein BI et al. | β | 2020 | β |
| Cigarette smoking dose-response and suicidal ideation among young people in Nepal: a cross-sectional study. | Sathian B et al. | β | 2020 | β |
| Bipolar disorder and tobacco smoking: Categorical and dimensional clinical correlates in subjects from the Brazilian bipolar research network. | Medeiros GC et al. | β | 2018 | β |
| Prevalence and Associated Features of Anxiety Disorder Comorbidity in Bipolar Disorder: A Meta-Analysis and Meta-Regression Study. | Yapici Eser H et al. | β | 2018 | β |
| The Convention on the Rights of Persons with Disabilities as a tobacco control tool in the mental health setting. | van der Eijk Y | β | 2018 | β |
| Associations among Substance Use, Mental Health Disorders, and Self-Harm in a Prison Population: Examining Group Risk for Suicide Attempt. | Gates ML et al. | β | 2017 | β |
| Does the number of previous mood episodes moderate the relationship between alcohol use, smoking and mood in bipolar outpatients? | Ter Meulen WG et al. | β | 2017 | β |
| Physical and mental health burden in cases of bipolar disorder classified as current, former, or non-tobacco smokers. | Icick R et al. | β | 2017 | β |
| Predictors of rehospitalization in a naturalistic cohort of patients with bipolar affective disorder. | O'Hagan M et al. | β | 2017 | β |
| Review of the efficacy of treatments for bipolar disorder and substance abuse. | Secades-Γlvarez A et al. | β | 2017 | β |
| Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder. | Lagerberg TV et al. | β | 2016 | β |
| Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type. | Estrada E et al. | β | 2016 | β |
| Reducing smoking reduces suicidality among individuals with psychosis: Complementary outcomes from a Healthy Lifestyles intervention study. | Sankaranarayanan A et al. | β | 2016 | β |
| A combined analysis of worldwide studies demonstrates an association between bipolar disorder and tobacco smoking behaviors in adults. | Jackson JG et al. | β | 2015 | β |
| A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. | Schaffer A et al. | β | 2015 | β |
| Smoking cessation and reduction in people with chronic mental illness. | Tidey JW et al. | β | 2015 | β |
| Smoking, Suicidality and Psychosis: A Systematic Meta-Analysis. | Sankaranarayanan A et al. | β | 2015 | β |
| Tobacco use in bipolar disorder. | Thomson D et al. | β | 2015 | β |
| Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates. | Di Florio A et al. | β | 2014 | β |
| Smoking and suicidality in patients with a psychotic disorder. | Sankaranarayanan A et al. | β | 2014 | β |
| Association between cigarette smoking and suicide in psychiatric inpatients. | Hooman S et al. | β | 2013 | β |
| Effectiveness of a multi-component Smoking Cessation Support Programme (McSCSP) for patients with severe mental disorders: study design. | Garcia-Portilla MP et al. | β | 2013 | β |
| Lifetime manic spectrum episodes and all-cause mortality: 26-year follow-up of the NIMH Epidemiologic Catchment Area Study. | Ramsey CM et al. | β | 2013 | β |
| Prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders. | Heffner JL et al. | β | 2013 | β |
| Smoking and suicidality in subjects with bipolar disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Baek JH et al. | β | 2013 | β |
| A Review of Smoking Cessation in Bipolar Disorder: Implications for Future Research. | George TP et al. | β | 2012 | β |
| Association between tobacco smoking and bipolar affective disorder: clinical, epidemiological, cross-sectional, retrospective study in outpatients. | Kreinin A et al. | β | 2012 | β |
| Cigarette smoking and its relationship to mood disorder symptoms and co-occurring alcohol and cannabis use disorders following first hospitalization for bipolar disorder. | Heffner JL et al. | β | 2012 | β |
| Impact of Abstinence Self-Efficacy and Treatment Services on Physical Health-Related Behaviors and Problems among Dually Diagnosed Patients. | Stein JA et al. | β | 2012 | β |
| Nicotine intake and smoking topography in smokers with bipolar disorder. | Williams JM et al. | β | 2012 | β |
| Smoking is associated with greater symptom load in bipolar disorder patients. | Saiyad M et al. | β | 2012 | β |
| Suicidal behavior in bipolar disorder: epidemiology, characteristics and major risk factors. | Gonda X et al. | β | 2012 | β |
| Tobacco smoking among people living with a psychotic illness: the second Australian Survey of Psychosis. | Cooper J et al. | β | 2012 | β |
| Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. | Pachas GN et al. | β | 2012 | β |
| Factors associated with work, social life and family life disability in bipolar disorder patients. | GutiΓ©rrez-Rojas L et al. | β | 2011 | β |
| Genetic association of bipolar disorder with the Ξ²(3) nicotinic receptor subunit gene. | Hartz SM et al. | β | 2011 | β |
| Risk factors of attempted suicide in bipolar disorder. | Cassidy F | β | 2011 | β |
| The co-occurrence of cigarette smoking and bipolar disorder: phenomenology and treatment considerations. | Heffner JL et al. | β | 2011 | β |
| The role of BDNF genetic polymorphisms in bipolar disorder with psychiatric comorbidities. | Neves FS et al. | β | 2011 | β |
| Varenicline for tobacco dependence: panacea or plight? | Williams JM et al. | β | 2011 | β |
| A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder. | Dodd S et al. | β | 2010 | β |
| Genetics of addictions. | Hartz SM et al. | β | 2010 | β |
| Genetics of addictions. | Hartz SM et al. | β | 2010 | β |
| Impact of substance use on the physical health of patients with bipolar disorder. | Garcia-Portilla MP et al. | β | 2010 | β |
| Increased risk for suicidal behavior in comorbid bipolar disorder and alcohol use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Oquendo MA et al. | β | 2010 | β |
| Predicting the course and outcome of bipolar disorder: a review. | Treuer T et al. | β | 2010 | β |
| Smoking, nicotine and neuropsychiatric disorders. | Dome P et al. | β | 2010 | β |
| Cigarette smoking is associated with suicidality in bipolar disorder. | Ostacher MJ et al. | β | 2009 | β |
| Coffee and cigarette use: association with suicidal acts in 352 Sardinian bipolar disorder patients. | Baethge C et al. | β | 2009 | β |
| Correlates of secondhand tobacco smoke exposure among persons with severe and persistent mental illness (SPMI) accessing community mental health services. | Okoli CT et al. | β | 2009 | β |
| Population-based prevalence of smoking in psychiatric inpatients: a focus on acute suicide risk and major diagnostic groups. | Lineberry TW et al. | β | 2009 | β |
| Relation between cigarette smoking and cognitive function in euthymic individuals with bipolar disorder. | Law CW et al. | β | 2009 | β |
| Smoking in psychiatric inpatients: association with working status, diagnosis, comorbid substance abuse and history of suicide attempts. | Keizer I et al. | β | 2009 | β |
| A preliminary study of sustained-release bupropion for smoking cessation in bipolar disorder. | Weinberger AH et al. | β | 2008 | β |
| Going up in smoke: tobacco smoking is associated with worse treatment outcomes in mania. | Berk M et al. | β | 2008 | β |
| Is there a relationship between elderly suicide rates and smoking? A cross-national study. | Shah A | β | 2008 | β |
| Predictors of dropout from group therapy among patients with bipolar and substance use disorders. | Graff FS et al. | β | 2008 | β |
| Quality of life in bipolar disorder patients: a comparison with a general population sample. | GutiΓ©rrez-Rojas L et al. | β | 2008 | β |
| Significance of cigarette smoking among youths with bipolar disorder. | Goldstein BI et al. | β | 2008 | β |
| Tobacco smoking within psychiatric inpatient settings: biopsychosocial perspective. | Olivier D et al. | β | 2007 | β |