Molecular, pharmacological and functional diversity of 5-HT receptors.
paper
Cited
Public
Unavailable
- Authors
- Hoyer, Daniel; Hannon, Jason P; Martin, Graeme R
- Year
- 2002
- Journal
- Pharmacology, biochemistry, and behavior
- PMID
- 11888546
- DOI
- 10.1016/s0091-3057(01)00746-8
Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors (GPCRs) and one (presumably a family of) ligand-gated ion channel(s). These receptors are divided into seven distinct classes (5-HT(1) to 5-HT(7)) largely on the basis of their structural and operational characteristics. Whilst this degree of physical diversity clearly underscores the physiological importance of serotonin, evidence for an even greater degree of operational diversity continues to emerge. The challenge for modern 5-HT research has therefore been to define more precisely the properties of the systems that make this incredible diversity possible. Much progress in this regard has been made during the last decade with the realisation that serotonin is possibly the least conservative monoamine transmitter and the cloning of its many receptors. Coupled with the actions of an extremely avid and efficient reuptake system, this array of receptor subtypes provides almost limitless signalling capabilities to the extent that one might even question the need for other transmitter systems. However, the complexity of the system appears endless, since posttranslational modifications, such as alternate splicing and RNA editing, increase the number of proteins, oligomerisation and heteromerisation increase the number of complexes, and multiple G-protein suggest receptor trafficking, allowing phenotypic switching and crosstalk within and possibly between receptor families. Whether all these possibilities are used in vivo under physiological or pathological conditions remains to be firmly established, but in essence, such variety will keep the 5-HT community busy for quite some time. Those who may have predicted that molecular biology would largely simplify the life of pharmacologists have missed the point for 5-HT research in particular and, most probably, for many other transmitters. This chapter is an attempt to summarise very briefly 5-HT receptor diversity. The reward for unravelling this complex array of serotonin receptor--effector systems may be substantial, the ultimate prize being the development of important new drugs in a range of disease areas.
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| Contribution of central sensitization to stress-induced spreading hyperalgesia in rats with orofacial inflammation. | Li JH et al. | β | 2020 | β |
| Current and emerging treatments targeting the neuroendocrine system for disorders of the skin and its appendages. | Soeberdt M et al. | β | 2020 | β |
| Gene expression of serotonergic markers in peripheral blood mononuclear cells of patients with late-onset Alzheimer's disease. | Neshan M et al. | β | 2020 | β |
| Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy. | Seifinejad A et al. | β | 2020 | β |
| Identification, characterization, and expression analysis of a serotonin receptor involved in the reproductive process of the Pacific abalone, Haliotis discus hannai. | Sharker MR et al. | β | 2020 | β |
| Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis. | Martin E et al. | β | 2020 | β |
| Interactions Between the Serotonergic and Other Neurotransmitter Systems in the Basal Ganglia: Role in Parkinson's Disease and Adverse Effects of L-DOPA. | MuΓ±oz A et al. | β | 2020 | β |
| Involvement of the dopamine D<sub>1</sub> receptor system in the anxiolytic effect of cedrol in the elevated plus maze and light-dark box tests. | Zhang K et al. | β | 2020 | β |
| Molecular evolution of a collage of cholesterol interaction motifs in transmembrane helix V of the serotonin<sub>1A</sub> receptor. | Fatakia SN et al. | β | 2020 | β |
| Neurochemical organization of the ventral striatum's olfactory tubercle. | Cansler HL et al. | β | 2020 | β |
| Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder. | Fuchs C et al. | β | 2020 | β |
| Plasma Serotonin in Laying Hens (<i>Gallus gallus domesticus</i>) With and Without Foot pad Dermatitis. | Alberghina D et al. | β | 2020 | β |
| Reward Contributions to Serotonergic Functions. | Liu Z et al. | β | 2020 | β |
| Role of 5-HT receptors in neuropathic pain: potential therapeutic implications. | Liu QQ et al. | β | 2020 | β |
| Serotonergic control of GABAergic inhibition in the lateral amygdala. | Yamamoto R et al. | β | 2020 | β |
| Serotonergic modulation of visual neurons in Drosophila melanogaster. | Sampson MM et al. | β | 2020 | β |
| Serotonin 5-HT<sub>1A</sub> and 5-HT<sub>1B</sub> receptors co-mediate the RU 24969-induced locomotor activity of male and female preweanling rats. | McDougall SA et al. | β | 2020 | β |
| Serotonin in Animal Cognition and Behavior. | BacquΓ©-Cazenave J et al. | β | 2020 | β |
| Serotonin Type 6 and 7 Receptors as a Novel Therapeutic Target for the Treatment of Schizophrenia. | Tsegay EW et al. | β | 2020 | β |
| Structural and functional characteristics of the special regulatory devices in the peripheral pulmonary circulation in rabbits. | Hussein MM | β | 2020 | β |
| Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives. | Zheng W et al. | β | 2020 | β |
| Targeting the 5-HT system: Potential side effects. | Hoyer D | β | 2020 | β |
| The role of 5-HT4 serotonin receptors in the CA1 hippocampal region on memory acquisition impairment induced by total (TSD) and REM sleep deprivation (RSD). | Eydipour Z et al. | β | 2020 | β |
| The Role of Serotonin in Singultus: A Review. | Petroianu GA et al. | β | 2020 | β |
| 5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines. | Toro-Sazo M et al. | β | 2019 | β |
| Amphetamine Self-Administration and Its Extinction Alter the 5-HT<sub>1B</sub> Receptor Protein Levels in Designated Structures of the Rat Brain. | Miszkiel J et al. | β | 2019 | β |
| An investigation of the single and combined effects of hypogravity and ionizing radiation on brain monoamine metabolism and rats' behavior. | Kokhan VS et al. | β | 2019 | β |
| Anxiolytic Effect of Cedrol on Behavior and Brain Neurotransmitter Levels of Female Mice. | Zhang K et al. | β | 2019 | β |
| Anxiolytic-like effects of the new arylpiperazine derivatives containing isonicotinic and picolinic nuclei: behavioral and biochemical studies. | KΔdzierska E et al. | β | 2019 | β |
| Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus. | Jafari-Sabet M et al. | β | 2019 | β |
| Dopamine D<sub>2L</sub> Receptor Deficiency Causes Stress Vulnerability through 5-HT<sub>1A</sub> Receptor Dysfunction in Serotonergic Neurons. | Shioda N et al. | β | 2019 | β |
| Drug-associated valvular heart diseases and serotonin-related pathways: a meta-analysis. | Fortier JH et al. | β | 2019 | β |
| Effect of a 5-HT<sub>2c</sub> receptor agonist on urethral closure mechanism in healthy women. | Klarskov N et al. | β | 2019 | β |
| Emotional Blunting, Cognitive Impairment, Bone Fractures, and Bleeding as Possible Side Effects of Long-Term Use of SSRIs. | Marazziti D et al. | β | 2019 | β |
| Estrogen and Serotonin: Complexity of Interactions and Implications for Epileptic Seizures and Epileptogenesis. | Pottoo FH et al. | β | 2019 | β |
| Evidence for protein kinase involvement in the 5-HT-[Ca<sup>2+</sup> ]<sub>i</sub> -pannexin-1 signalling pathway in type II glial cells of the rat carotid body. | Leonard EM et al. | β | 2019 | β |
| Expression of serotonin 2A, 2C, 6 and 7 receptor and IL-6 mRNA in experimental toxoplasmic encephalitis in mice. | Atmaca HT | β | 2019 | β |
| Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy. | Cao L et al. | β | 2019 | β |
| In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates. | Prabhakaran J et al. | β | 2019 | β |
| JC Polyomavirus Entry by Clathrin-Mediated Endocytosis Is Driven by Ξ²-Arrestin. | Mayberry CL et al. | β | 2019 | β |
| Kinetic analysis of [<sup>18</sup>F] altanserin bolus injection in the canine brain using PET imaging. | Pauwelyn G et al. | β | 2019 | β |
| Modulatory effects of cannabinoids on brain neurotransmission. | Cohen K et al. | β | 2019 | β |
| Molecular Cloning and Expression Analysis of 5-hydroxytryptamine Receptor 7 in Ant Polyrhachis vicina Roger (Hymenoptera: Formicidae). | Yang S et al. | β | 2019 | β |
| Motor cortex and pain control: exploring the descending relay analgesic pathways and spinal nociceptive neurons in healthy conscious rats. | Lopes PSS et al. | β | 2019 | β |
| Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity. | Vahid-Ansari F et al. | β | 2019 | β |
| PET quantification of [18F]MPPF in the canine brain using blood input and reference tissue modelling. | Pauwelyn G et al. | β | 2019 | β |
| Potentiation of the glycine response by serotonin on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice. | Nguyen HTT et al. | β | 2019 | β |
| Protective effects of sumatriptan on ischaemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes of rat. | Dejban P et al. | β | 2019 | β |
| QSAR Analysis of Multimodal Antidepressants Vortioxetine Analogs Using Physicochemical Descriptors and MLR Modeling. | Rajathei DM et al. | β | 2019 | β |
| RNA Editing of Serotonin 2C Receptor and Alcohol Intake. | Tanaka M et al. | β | 2019 | β |
| Serotonergic modulation of visual neurons in<i>Drosophila melanogaster</i> | Sampson MM et al. | β | 2019 | β |
| Serotonergic regulation of insulin secretion. | Cataldo BascuΓ±an LR et al. | β | 2019 | β |
| Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder. | Murnane KS | β | 2019 | β |
| Serotonin 5-HT<sub>2C</sub> Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro. | Land MA et al. | β | 2019 | β |
| Serotonin and motherhood: From molecules to mood. | Pawluski JL et al. | β | 2019 | β |
| Serotonin and orthodontic tooth movement. | Dhenain T et al. | β | 2019 | β |
| Serotonin contribution to cardiac valve degeneration: new insights for novel therapies? | Ayme-Dietrich E et al. | β | 2019 | β |
| Serotonin, hematopoiesis and stem cells. | Fouquet G et al. | β | 2019 | β |
| Serotonin Receptor 1A Variation Is Associated with Anxiety and Agonistic Behavior in Chimpanzees. | Staes N et al. | β | 2019 | β |
| Spermatozoa motility in bivalves: Signaling, flagellar beating behavior, and energetics. | Boulais M et al. | β | 2019 | β |
| Spinal 5-HT<sub>3</sub> receptor contributes to somatic hyperalgesia induced by sub-chronic stress. | Li ZL et al. | β | 2019 | β |
| Studies on the antifungal and serotonin receptor agonist activities of the secondary metabolites from piezotolerant deep-sea fungus <i>Ascotricha</i> sp. | Ganesh Kumar A et al. | β | 2019 | β |
| SUVN-502, a novel, potent, pure, and orally active 5-HT6 receptor antagonist: pharmacological, behavioral, and neurochemical characterization. | Nirogi R et al. | β | 2019 | β |
| Synthesis, docking studies, and pharmacological evaluation of 5HT<sub>2C</sub> ligands containing the N'-cyanoisonicotinamidine or N'-cyanopicolinamidine nucleus. | Magli E et al. | β | 2019 | β |
| The exploration of novel Alzheimer's therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches. | Hassan M et al. | β | 2019 | β |
| The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. | Volpicelli F et al. | β | 2019 | β |
| 5-HT<sub>2</sub> and 5-HT<sub>2B</sub> antagonists attenuate pro-fibrotic phenotype in human adult dermal fibroblasts by blocking TGF-Ξ²1 induced non-canonical signaling pathways including STAT3 : implications for fibrotic diseases like scleroderma. | Chaturvedi S et al. | β | 2018 | β |
| ADSA Foundation Scholar Award: A role for serotonin in lactation physiology-Where do we go from here? | Hernandez LL | β | 2018 | β |
| Analysis and measurement of serotonin. | Szeitz A et al. | β | 2018 | β |
| Association of Serotonin Receptors with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis. | Hou YW et al. | β | 2018 | β |
| Corticosterone and serotonin similarly influence GABAergic and purinergic pathways to affect cortical inhibitory networks. | Wotton CA et al. | β | 2018 | β |
| DPCPX, a selective adenosine A1 receptor antagonist, enhances the antidepressant-like effects of imipramine, escitalopram, and reboxetine in mice behavioral tests. | Szopa A et al. | β | 2018 | β |
| Effect of a 5-HT2c receptor agonist on urethral closure mechanisms in female rats. | Ouchi M et al. | β | 2018 | β |
| Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts. | Gocht A et al. | β | 2018 | β |
| Evaluation of Neurotransmitter Alterations in Four Distinct Brain Regions After Rapid Eye Movement Sleep Deprivation (REMSD) Induced Mania-Like Behaviour in Swiss Albino Mice. | Siddique SA et al. | β | 2018 | β |
| Evidence for astrocyte purinergic signaling in cortical sensory adaptation and serotonin-mediated neuromodulation. | Quon EF et al. | β | 2018 | β |
| Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans. | Frederiksen SD et al. | β | 2018 | β |
| Functional Organization of the Sympathetic Pathways Controlling the Pupil: Light-Inhibited and Light-Stimulated Pathways. | Szabadi E | β | 2018 | β |
| Further investigation of the effects of 5-hydroxytryptamine, 8-OH-DPAT and DOI to mediate contraction and relaxation responses in the intestine and emesis in Suncus murinus. | Javid FA et al. | β | 2018 | β |
| GPCRs in pulmonary arterial hypertension: tipping the balance. | Iyinikkel J et al. | β | 2018 | β |
| Hallucinogens and Serotonin 5-HT<sub>2A</sub> Receptor-Mediated Signaling Pathways. | LΓ³pez-GimΓ©nez JF et al. | β | 2018 | β |
| Identification of Sphingolipid-binding Motif in G Protein-coupled Receptors. | Shrivastava S et al. | β | 2018 | β |
| Invertebrate serotonin receptors: a molecular perspective on classification and pharmacology. | Tierney AJ | β | 2018 | β |
| Involvement of classical neurotransmitter systems in memory reconsolidation: Focus on destabilization. | Wideman CE et al. | β | 2018 | β |
| Mode of action characterization for adverse effect of propranolol in Daphnia magna based on behavior and physiology monitoring and metabolite profiling. | Jeong TY et al. | β | 2018 | β |
| Novel Bivalent 5-HT<sub>2A</sub> Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo. | Soto CA et al. | β | 2018 | β |
| Opioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects. | Baldo BA | β | 2018 | β |
| Pharmacological evidence of involvement of nitric oxide pathway in anti-pruritic effects of sumatriptan in chloroquine-induced scratching in mice. | Haddadi NS et al. | β | 2018 | β |
| Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands. | Rague A et al. | β | 2018 | β |
| Presynaptic serotonin 5-HT<sub>1B/D</sub> receptor-mediated inhibition of glycinergic transmission to the frog spinal motoneurons. | Kalinina NI et al. | β | 2018 | β |
| Search for a 5-CT alternative. <i>In vitro</i> and <i>in vivo</i> evaluation of novel pharmacological tools: 3-(1-alkyl-1<i>H</i>-imidazol-5-yl)-1<i>H</i>-indole-5-carboxamides, low-basicity 5-HT<sub>7</sub> receptor agonists. | Latacz G et al. | β | 2018 | β |
| Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation. | Driesbaugh KH et al. | β | 2018 | β |
| Sex Differences and Estrous Cycle Effects of Peripheral Serotonin-Evoked Rodent Pain Behaviors. | Kaur S et al. | β | 2018 | β |
| SSRI-reduced platelet reactivity in non-responding patients with life-long Recurrent Depressive Disorder: Detection and involved mechanisms. | Aleksovski B et al. | β | 2018 | β |
| TCB-2 [(7R)-3-bromo-2, 5-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl]methanamine]: A hallucinogenic drug, a selective 5-HT<sub>2A</sub> receptor pharmacological tool, or none of the above? | Di Giovanni G et al. | β | 2018 | β |
| The 5-HT<sub>1B</sub> receptor - a potential target for antidepressant treatment. | Tiger M et al. | β | 2018 | β |
| The anxiolytic effect of Juniperus virginiana L. essential oil and determination of its active constituents. | Zhang K et al. | β | 2018 | β |
| The current limits in virtual screening and property prediction. | Hutter MC | β | 2018 | β |
| The novel, potent and highly selective 5-HT<sub>4</sub> receptor agonist YH12852 significantly improves both upper and lower gastrointestinal motility. | Jeong EJ et al. | β | 2018 | β |
| The Role of Serotonin during Skin Healing in Post-Thermal Injury. | Sadiq A et al. | β | 2018 | β |
| Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes. | Camicia F et al. | β | 2018 | β |
| 5-HT<sub>7</sub> receptor-mediated fear conditioning and possible involvement of extracellular signal-regulated kinase. | Takeda K et al. | β | 2017 | β |
| Activation of 5-HT<sub>7</sub> receptors reverses NMDA-R-dependent LTD by activating PKA in medial vestibular neurons. | Li YH et al. | β | 2017 | β |
| Anatomy and behavioral function of serotonin receptors in Drosophila melanogaster larvae. | Huser A et al. | β | 2017 | β |
| A short history of the 5-HT<sub>2C</sub> receptor: from the choroid plexus to depression, obesity and addiction treatment. | Palacios JM et al. | β | 2017 | β |
| Behavioral Effects of Systemic, Infralimbic and Prelimbic Injections of a Serotonin 5-HT<sub>2A</sub> Antagonist in Carioca High- and Low-Conditioned Freezing Rats. | LeΓ³n LA et al. | β | 2017 | β |
| Blunted 5-HT<sub>1A</sub> receptor-mediated responses and antidepressant-like behavior in mice lacking the GABA<sub>B1a</sub> but not GABA<sub>B1b</sub> subunit isoforms. | Jacobson LH et al. | β | 2017 | β |
| Characterization of serotonin-induced inhibition of excitatory synaptic transmission in the anterior cingulate cortex. | Tian Z et al. | β | 2017 | β |
| Characterization of three serotonin receptors from the small white butterfly, Pieris rapae. | Qi YX et al. | β | 2017 | β |
| Chronic fluoxetine rescues changes in plasma membrane density of 5-HT1A autoreceptors and serotonin transporters in the olfactory bulbectomy rodent model of depression. | Riad M et al. | β | 2017 | β |
| Comparing the Expression of Genes Related to Serotonin (5-HT) in C57BL/6J Mice and Humans Based on Data Available at the Allen Mouse Brain Atlas and Allen Human Brain Atlas. | Acevedo-Triana CA et al. | β | 2017 | β |
| Contribution of Impulsivity and Serotonin Receptor Neuroadaptations to the Development of an MDMA ('Ecstasy') Substance Use Disorder. | Schenk S et al. | β | 2017 | β |
| Desensitization of the human 5-HT<sub>4</sub> receptor in isolated atria of transgenic mice. | Gergs U et al. | β | 2017 | β |
| Disinhibition of the rat prelimbic cortex promotes serotonergic activation of the dorsal raphe nucleus and panicolytic-like behavioral effects. | Yamashita PS et al. | β | 2017 | β |
| Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. | Song NN et al. | β | 2017 | β |
| Fluorogenic Targeting of Voltage-Sensitive Dyes to Neurons. | Liu P et al. | β | 2017 | β |
| From Homology Models to a Set of Predictive Binding Pockets-a 5-HT<sub>1A</sub> Receptor Case Study. | Warszycki D et al. | β | 2017 | β |
| Gender Differences in Serotonin Signaling in Patients with Diarrhea-predominant Irritable Bowel Syndrome. | Katsumata R et al. | β | 2017 | β |
| Genetic and biochemical changes of the serotonergic system in migraine pathobiology. | Gasparini CF et al. | β | 2017 | β |
| Hierarchy in the home cage affects behaviour and gene expression in group-housed C57BL/6 male mice. | Horii Y et al. | β | 2017 | β |
| Identification and functional characterisation of 5-HT4 receptor in sea cucumber Apostichopus japonicus (Selenka). | Wang T et al. | β | 2017 | β |
| Inhibition of serotonin receptor type 1 in acute myeloid leukemia impairs leukemia stem cell functionality: a promising novel therapeutic target. | Etxabe A et al. | β | 2017 | β |
| Interaction between hippocampal serotonin and cannabinoid systems in reactivity to spatial and object novelty detection. | Nasehi M et al. | β | 2017 | β |
| JC Polyomavirus Attachment and Entry: Potential Sites for PML Therapeutics. | Mayberry CL et al. | β | 2017 | β |
| Lamotrigine, an antiepileptic drug, inhibits 5-HT<sub>3</sub> receptor currents in NCB-20 neuroblastoma cells. | Kim KJ et al. | β | 2017 | β |
| Lentiviral vector-driven inhibition of 5-HT synthesis in B3 bulbo-spinal serotonergic projections - Consequences on nociception, inflammatory and neuropathic pain in rats. | Gautier A et al. | β | 2017 | β |
| Low-basicity 5-HT<sub>7</sub> Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol. | Hogendorf AS et al. | β | 2017 | β |
| Marine Inspired 2-(5-Halo-1H-indol-3-yl)-N,N-dimethylethanamines as Modulators of Serotonin Receptors: An Example Illustrating the Power of Bromine as Part of the Uniquely Marine Chemical Space. | Ibrahim MA et al. | β | 2017 | β |
| Maturation, Refinement, and Serotonergic Modulation of Cerebellar Cortical Circuits in Normal Development and in Murine Models of Autism. | Hoxha E et al. | β | 2017 | β |
| Neurotransmitters: The Critical Modulators Regulating Gut-Brain Axis. | Mittal R et al. | β | 2017 | β |
| New 5-HT<sub>1A</sub>, 5HT<sub>2A</sub> and 5HT<sub>2C</sub> receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation. | Fiorino F et al. | β | 2017 | β |
| Pathophysiology of Migraine: A Disorder of Sensory Processing. | Goadsby PJ et al. | β | 2017 | β |
| Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391. | Ferreira Junior WA et al. | β | 2017 | β |
| Prucalopride for the treatment of ileus. | Smart CJ et al. | β | 2017 | β |
| Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms. | Huang X et al. | β | 2017 | β |
| Serotonergic Control of Metabolic Homeostasis. | Wyler SC et al. | β | 2017 | β |
| Serotonergic Mechanisms Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. | Terry N et al. | β | 2017 | β |
| Serotonergic modulation of the activity of mesencephalic dopaminergic systems: Therapeutic implications. | De DeurwaerdΓ¨re P et al. | β | 2017 | β |
| Serotonergic transmission at Merkel discs: modulation by exogenously applied chemical messengers and involvement of I<sub>h</sub> currents. | Chang W et al. | β | 2017 | β |
| Serotonin and urocortin 1 in the dorsal raphe and Edinger-Westphal nuclei after early life stress in serotonin transporter knockout rats. | van der Doelen RHA et al. | β | 2017 | β |
| Serotonin gating of cortical and thalamic glutamate inputs onto principal neurons of the basolateral amygdala. | Guo JD et al. | β | 2017 | β |
| Sleep deprivation induces changes in 5-HT actions and 5-HT<sub>1A</sub> receptor expression in the rat hippocampus. | Azizi H et al. | β | 2017 | β |
| Spinal 5-HT<sub>4</sub> and 5-HT<sub>6</sub> receptors contribute to the maintenance of neuropathic pain in rats. | Pineda-Farias JB et al. | β | 2017 | β |
| Systems Biology Genetic Approach Identifies Serotonin Pathway as a Possible Target for Obstructive Sleep Apnea: Results from a Literature Search Review. | Jagannathan R et al. | β | 2017 | β |
| The 5-HT<sub>3</sub> Receptor Antagonist Ondansetron Attenuates Pancreatic Injury in Cerulein-Induced Acute Pancreatitis Model. | Tsukamoto A et al. | β | 2017 | β |
| The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors. | Segi-Nishida E | β | 2017 | β |
| The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT<sub>1A</sub> receptor over Ξ±<sub>1</sub>-adrenoceptor andΒ D<sub>2</sub>-like receptor subtypes. | Del Bello F et al. | β | 2017 | β |
| The serotonin 5-HT<sub>2C</sub> receptor and the non-addictive nature of classic hallucinogens. | Canal CE et al. | β | 2017 | β |
| The Serotonin Receptor Subtype 5b Specifically Interacts with Serotonin Receptor Subtype 1A. | Niebert S et al. | β | 2017 | β |
| Translational issues for human corneal endothelial tissue engineering. | Soh YQ et al. | β | 2017 | β |
| 5-HT2A Serotonin Receptor Density in Adult Male Rats' Hippocampus after Morphine-based Conditioned Place Preference. | Mohammadi R et al. | β | 2016 | β |
| 5-HT2C receptors in psychiatric disorders: A review. | Chagraoui A et al. | β | 2016 | β |
| 5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives. | Bielenica A et al. | β | 2016 | β |
| 5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity. | Kim Y et al. | β | 2016 | β |
| A 5-HT2A/2C receptor agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, mitigates developmental neurotoxicity of ethanol to serotonergic neurons. | Ishiguro T et al. | β | 2016 | β |
| Adrenergic signaling in teleost fish liver, a challenging path. | Fabbri E et al. | β | 2016 | β |
| Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses. | Krishnan B | β | 2016 | β |
| A novel optical biosensor for direct and selective determination of serotonin in serum by Solid Surface-Room Temperature Phosphorescence. | Ramon-Marquez T et al. | β | 2016 | β |
| Antinociceptive effects of vitexin in a mouse model of postoperative pain. | Zhu Q et al. | β | 2016 | β |
| Antistress Effects of Rosa rugosa Thunb. on Total Sleep Deprivation-Induced Anxiety-Like Behavior and Cognitive Dysfunction in Rat: Possible Mechanism of Action of 5-HT6 Receptor Antagonist. | Na JR et al. | β | 2016 | β |
| A review of 5-HT transporter linked promoter region (5-HTTLPR) polymorphism and associations with alcohol use problems and sexual risk behaviors. | Rubens M et al. | β | 2016 | β |
| Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans. | Alam T et al. | β | 2016 | β |
| Blockade of 5-HT2A receptors at the site of inflammation inhibits activation of spinal dorsal horn neurons in rats. | Hu W et al. | β | 2016 | β |
| Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. | Sagarduy A et al. | β | 2016 | β |
| Change in vascular smooth muscle response to 5-HT due to short- or long-term endothelial denudation of the bovine digital vein. | Punzi S et al. | β | 2016 | β |
| Chemical anatomy of pallidal afferents in primates. | Eid L et al. | β | 2016 | β |
| Cholinergic and serotonergic modulation of visual information processing in monkey V1. | Shimegi S et al. | β | 2016 | β |
| Circuits Regulating Pleasure and Happiness-Mechanisms of Depression. | Loonen AJ et al. | β | 2016 | β |
| Comprehensive Immunolocalization Studies of a Putative Serotonin Receptor from the Alimentary Canal of Aedes aegypti Larvae Suggest Its Diverse Roles in Digestion and Homeostasis. | Petrova A et al. | β | 2016 | β |
| Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca(2+)-activated chloride channels. | Salzer I et al. | β | 2016 | β |
| Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands. | Ofori E et al. | β | 2016 | β |
| Do dorsal raphe 5-HT neurons encode "beneficialness"? | Luo M et al. | β | 2016 | β |
| Drug Development in Alzheimer's Disease: The Contribution of PET and SPECT. | Declercq LD et al. | β | 2016 | β |
| Duloxetine-related posterior reversible encephalopathy syndrome: A case report. | Zappella N et al. | β | 2016 | β |
| Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression. | Le JJ et al. | β | 2016 | β |
| Expression of serotonin receptors in the colonic tissue of chronic diarrhea rats. | Zhu T et al. | β | 2016 | β |
| Importance of astrocytes for potassium ion (K<sup>+</sup>) homeostasis in brain and glial effects of K<sup>+</sup> and its transporters on learning. | Hertz L et al. | β | 2016 | β |
| Inhibition of Peripheral Synthesis of Serotonin as a New Target in Neuroendocrine Tumors. | Molina-Cerrillo J et al. | β | 2016 | β |
| Intraspinal serotonergic neurons consist of two, temporally distinct populations in developing zebrafish. | Montgomery JE et al. | β | 2016 | β |
| In Vivo Evaluation of Blood Based and Reference Tissue Based PET Quantifications of [11C]DASB in the Canine Brain. | Van Laeken N et al. | β | 2016 | β |
| Lack of association between the serotonin transporter and serotonin 1A receptor: an in vivo PET imaging study in healthy adults. | Strupp-Levitsky M et al. | β | 2016 | β |
| Long-Term Citalopram Treatment Alters the Stress Responses of the Cortical Dopamine and Noradrenaline Systems: the Role of Cortical 5-HT1A Receptors. | Kaneko F et al. | β | 2016 | β |
| Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver. | Fu J et al. | β | 2016 | β |
| Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder. | Tiger M et al. | β | 2016 | β |
| Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals. | Chang W et al. | β | 2016 | β |
| Modulation of auditory brainstem responses by serotonin and specific serotonin receptors. | Papesh MA et al. | β | 2016 | β |
| Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning. | Nasehi M et al. | β | 2016 | β |
| Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases. | Di Giovanni G et al. | β | 2016 | β |
| New therapeutic opportunities for 5-HT2C receptor ligands in neuropsychiatric disorders. | Di Giovanni G et al. | β | 2016 | β |
| Novel N-acyl-carbazole derivatives as 5-HT7R antagonists. | Kim Y et al. | β | 2016 | β |
| Oh, the places you'll go! My many colored serotonin (apologies to Dr. Seuss). | Watts SW | β | 2016 | β |
| Panic-modulating effects of alprazolam, moclobemide and sumatriptan in the rat elevated T-maze. | Sant'Ana AB et al. | β | 2016 | β |
| Prolonged drug-induced myoclonus: is it related to palonosetron? | Chaw SH et al. | β | 2016 | β |
| Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. | Pei S et al. | β | 2016 | β |
| Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures. | Venzi M et al. | β | 2016 | β |
| Role of 5-HT5A and 5-HT1B/1D receptors in the antinociception produced by ergotamine and valerenic acid in the rat formalin test. | Vidal-CantΓΊ GC et al. | β | 2016 | β |
| Role of spinal 5-HT2 receptors subtypes in formalin-induced long-lasting hypersensitivity. | Cervantes-DurΓ‘n C et al. | β | 2016 | β |
| Serotonergic regulation of distention-induced ATP release from the urothelium. | Matsumoto-Miyai K et al. | β | 2016 | β |
| Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells. | Hansson B et al. | β | 2016 | β |
| Serotonin-Exacerbated DSS-Induced Colitis Is Associated with Increase in MMP-3 and MMP-9 Expression in the Mouse Colon. | Chen M et al. | β | 2016 | β |
| Serotonin Improves High Fat Diet Induced Obesity in Mice. | Watanabe H et al. | β | 2016 | β |
| Serotonin-induced contractile responses of esophageal smooth muscle in the house musk shrew (Suncus murinus). | Shiina T et al. | β | 2016 | β |
| Serotonin Receptor 2B Mediates Mechanical Hyperalgesia by Regulating Transient Receptor Potential Vanilloid 1. | Su YS et al. | β | 2016 | β |
| Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever. | Cui L et al. | β | 2016 | β |
| Stimulation of contractions in pregnant human myometrium is associated with 5-HT3 receptors. | Li H et al. | β | 2016 | β |
| Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus. | Fiorino F et al. | β | 2016 | β |
| The anxiolytic effect of essential oil of Cananga odorata exposure on mice and determination of its major active constituents. | Zhang N et al. | β | 2016 | β |
| The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice. | Dong Y et al. | β | 2016 | β |
| [The pharmacological basis of the serotonin system: Application to antidepressant response]. | David DJ et al. | β | 2016 | β |
| The potential role of serotonergic mechanisms in the spinal oxytocin-induced antinociception. | GodΓnez-Chaparro B et al. | β | 2016 | β |
| The serotonergic system and cognitive function. | Ε vob Ε trac D et al. | β | 2016 | β |
| Understanding the impact of 5-HTTLPR, antidepressants, and acute tryptophan depletion on brain activation during facial emotion processing: A review of the imaging literature. | Raab K et al. | β | 2016 | β |
| Zerumbone alleviates chronic constriction injury-induced allodynia and hyperalgesia through serotonin 5-HT receptors. | Chia JSM et al. | β | 2016 | β |
| 5-HT1A receptor-dependent control of nigrostriatal dopamine neurotransmission in the pharmacotherapy of Parkinson's disease and schizophrenia. | Haleem DJ | β | 2015 | β |
| 5-HT3 receptors antagonists reduce serotonin-induced scratching in mice. | Ostadhadi S et al. | β | 2015 | β |
| 5-HT7 receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin. | Kusek M et al. | β | 2015 | β |
| 5-HT<sub>2B</sub> Receptor Antagonists Reduce Nerve Injury-Induced Tactile Allodynia and Expression of 5-HT<sub>2B</sub> Receptors. | Pineda-Farias JB et al. | β | 2015 | β |
| 5-hydroxytryptamine medications for the treatment of obesity. | Burke LK et al. | β | 2015 | β |
| 6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands. | Larchanche PE et al. | β | 2015 | β |
| Activation of 5-HT1A receptors in the preBΓΆtzinger region has little impact on the respiratory pattern. | Radocaj T et al. | β | 2015 | β |
| Alteration of Airway Reactivity and Reduction of Ryanodine Receptor Expression by Cigarette Smoke in Mice. | Donovan C et al. | β | 2015 | β |
| Alterations of cognitive function and 5-HT system in rats after long term microwave exposure. | Li HJ et al. | β | 2015 | β |
| Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes. | Bennet H et al. | β | 2015 | β |
| Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands. | PittalΓ V et al. | β | 2015 | β |
| Antidepressant-like activity of Tagetes lucida Cav. is mediated by 5-HT(1A) and 5-HT(2A) receptors. | Bonilla-Jaime H et al. | β | 2015 | β |
| A review on alcohol: from the central action mechanism to chemical dependency. | Costardi JV et al. | β | 2015 | β |
| Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of Ξ²-arrestin-2. | Stroth N et al. | β | 2015 | β |
| Atypical antipsychotics and inverse agonism at 5-HT2 receptors. | Sullivan LC et al. | β | 2015 | β |
| Beta-adrenergic blockade increases GLUT4 and improves glycemic control in insulin-treated diabetic Wistar rats. | Alves-Wagner AB et al. | β | 2015 | β |
| Biased signalling: the instinctive skill of the cell in the selection of appropriate signalling pathways. | Liu Y et al. | β | 2015 | β |
| Circuitry and plasticity of the dorsal horn--toward a better understanding of neuropathic pain. | West SJ et al. | β | 2015 | β |
| Cronobacter sakazakii infection alters serotonin transporter and improved fear memory retention in the rat. | Sivamaruthi BS et al. | β | 2015 | β |
| Current developments in pharmacological therapeutics for chronic constipation. | Jiang C et al. | β | 2015 | β |
| Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists. | Nirogi RV et al. | β | 2015 | β |
| Differential expression of 5-HT-related genes in symptomatic pulmonary embolism patients. | Jin Y et al. | β | 2015 | β |
| Differential modulation of phasic and tonic inhibition underlies serotonergic suppression of long-term potentiation in the rat visual cortex. | Jang HJ et al. | β | 2015 | β |
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HTβ F receptor agonists: Evolution from bicyclic to monocyclic cores. | Zhang D et al. | β | 2015 | β |
| Diurnal and seasonal variation of the brain serotonin system in healthy male subjects. | Matheson GJ et al. | β | 2015 | β |
| Enhancement of GluN2B Subunit-Containing NMDA Receptor Underlies Serotonergic Regulation of Long-Term Potentiation after Critical Period in the Rat Visual Cortex. | Joo K et al. | β | 2015 | β |
| Environmentally relevant concentrations of citalopram partially inhibit feeding in the three-spine stickleback (Gasterosteus aculeatus). | Kellner M et al. | β | 2015 | β |
| Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HTβ Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs. | Herth MM et al. | β | 2015 | β |
| Exogenous Tryptophan Promotes Cutaneous Wound Healing of Chronically Stressed Mice through Inhibition of TNF-Ξ± and IDO Activation. | Bandeira LG et al. | β | 2015 | β |
| Experimental Verification of the Effects on Normal Domestic Cats by Feeding Prescription Diet for Decreasing Stress. | Miyaji K et al. | β | 2015 | β |
| Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia. | Imamura T et al. | β | 2015 | β |
| Expression of serotonin receptors in human lower esophageal sphincter. | Li HF et al. | β | 2015 | β |
| Fingerprint-based consensus virtual screening towards structurally new 5-HT(6)R ligands. | Smusz S et al. | β | 2015 | β |
| Functional Selectivity and Antidepressant Activity of Serotonin 1A Receptor Ligands. | Chilmonczyk Z et al. | β | 2015 | β |
| Inhibition of apomorphine-induced behavioral sensitization in rats pretreated with fluoxetine. | Haleem DJ et al. | β | 2015 | β |
| In Vitro Early Safety Pharmacology Screening: Perspectives Related to Cardiovascular Safety. | Gintant G | β | 2015 | β |
| Involvement of the serotonergic system in the anxiolytic-like effect of 2-phenylethynyl butyltellurium in mice. | Quines CB et al. | β | 2015 | β |
| Linoleic acid derivative DCP-LA ameliorates stress-induced depression-related behavior by promoting cell surface 5-HT1A receptor translocation, stimulating serotonin release, and inactivating GSK-3Ξ². | Kanno T et al. | β | 2015 | β |
| Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. | Bonasera SJ et al. | β | 2015 | β |
| Pharmacodynamic Study of Interaction of Aqueous Leaf Extract of Psidium Guajava Linn. (Myrtaceae) with Receptor Systems Using Isolated Tissue Preparations. | Mahaseth RK et al. | β | 2015 | β |
| Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study. | Selvaraj S et al. | β | 2015 | β |
| Reduction of Methylphenidate Induced Anxiety, Depression and Cognition Impairment by Various doses of Venlafaxine in Rat. | Motaghinejad M et al. | β | 2015 | β |
| Regulatory Effects of 5-Hydroxytryptamine Receptors on Voiding Function. | Matsumoto-Miyai K et al. | β | 2015 | β |
| Rodent models of treatment-resistant depression. | Caldarone BJ et al. | β | 2015 | β |
| Role of spinal 5-HT5A, and 5-HT1A/1B/1D, receptors in neuropathic pain induced by spinal nerve ligation in rats. | Avila-Rojas SH et al. | β | 2015 | β |
| S100B interacts with the serotonin 5-HT7 receptor to regulate a depressive-like behavior. | Stroth N et al. | β | 2015 | β |
| Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice. | Morici JF et al. | β | 2015 | β |
| Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex. | Nocjar C et al. | β | 2015 | β |
| Serotonin and colonic motility. | Kendig DM et al. | β | 2015 | β |
| Serotonin controlling feeding and satiety. | Voigt JP et al. | β | 2015 | β |
| Serotonin induces peripheral mechanical antihyperalgesic effects in mice. | Diniz DA et al. | β | 2015 | β |
| Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity. | Klaassens BL et al. | β | 2015 | β |
| Sphingolipids in the function of G protein-coupled receptors. | Jafurulla M et al. | β | 2015 | β |
| Stimulation of 5-HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas. | Nativio P et al. | β | 2015 | β |
| Synthesis and in vitro evaluation of [18F]FECIMBI-36: A potential agonist PET ligand for 5-HT2A/2C receptors. | Prabhakaran J et al. | β | 2015 | β |
| The 5-HTTLPR confers susceptibility to anorexia nervosa in Han Chinese: evidence from a case-control and family-based study. | Chen J et al. | β | 2015 | β |
| The murine serotonin syndrome - evaluation of responses to 5-HT-enhancing drugs in NMRI mice. | Haberzettl R et al. | β | 2015 | β |
| The role of serotonin 5-HT2A receptors in memory and cognition. | Zhang G et al. | β | 2015 | β |
| The role of the serotonin receptor subtypes 5-HT1A and 5-HT7 and its interaction in emotional learning and memory. | Stiedl O et al. | β | 2015 | β |
| The sleep-wake cycle and motor activity, but not temperature, are disrupted over the light-dark cycle in mice genetically depleted of serotonin. | Solarewicz JZ et al. | β | 2015 | β |
| The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model. | Hong SS et al. | β | 2015 | β |
| Unraveling the modulatory actions of serotonin on male rat sexual responses. | Rubio-Casillas A et al. | β | 2015 | β |
| Unusual reactivity of Ξ²-hydroxy-serotonin, a forgotten serotonin derivative. | Kawashima T et al. | β | 2015 | β |
| Yokukansan Increases 5-HT1A Receptors in the Prefrontal Cortex and Enhances 5-HT1A Receptor Agonist-Induced Behavioral Responses in Socially Isolated Mice. | Ueki T et al. | β | 2015 | β |
| 5-HT1A/1B receptors as targets for optimizing pigmentary responses in C57BL/6 mouse skin to stress. | Wu HL et al. | β | 2014 | β |
| 5-HT7 receptors are involved in neurogenic dural vasodilatation in an experimental model of migraine. | Wang X et al. | β | 2014 | β |
| 5-HT7 receptor signaling: improved therapeutic strategy in gut disorders. | Kim JJ et al. | β | 2014 | β |
| 5-HT7 receptor stimulation and blockade: a therapeutic paradox about memory formation and amnesia. | Meneses A | β | 2014 | β |
| Administration of memantine during withdrawal mitigates overactivity and spatial learning impairments associated with neonatal alcohol exposure in rats. | Idrus NM et al. | β | 2014 | β |
| Application of chromatographic data in QSAR Studies of 3-[Ο-(4-Arylpiperazin-1-yl)alkyl]pyrimido[5,4-c]quinolin-4(3H)-one derivatives as 5-HT1A receptor ligands. | Ε»ydek G et al. | β | 2014 | β |
| Biomarkers of cognitive dysfunction in traumatic brain injury. | Sun ZL et al. | β | 2014 | β |
| Blockade of 5-Ht3 receptors in the septal area increases Fos expression in selected brain areas. | Urzedo-Rodrigues LS et al. | β | 2014 | β |
| Constipation-predominant irritable bowel syndrome: a review of current and emerging drug therapies. | Jadallah KA et al. | β | 2014 | β |
| Deletion of serotonin 2B receptor provokes structural alterations of mouse dental tissues. | Dimitrova-Nakov S et al. | β | 2014 | β |
| Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling. | Zhao ZQ et al. | β | 2014 | β |
| Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HTβ receptor. | Lacivita E et al. | β | 2014 | β |
| Distribution of serotonin 4(a) receptors in the juvenile rat brain and spinal cord. | Suwa B et al. | β | 2014 | β |
| Dorsal raphe neurons signal reward through 5-HT and glutamate. | Liu Z et al. | β | 2014 | β |
| Drugs, genes and the blues: pharmacogenetics of the antidepressant response from mouse to man. | O'Leary OF et al. | β | 2014 | β |
| Editorial. Thematic section: serotonin and its receptors. | Albert PR | β | 2014 | β |
| Effect of peripheral 5-HT on glucose and lipid metabolism in wether sheep. | Watanabe H et al. | β | 2014 | β |
| Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. | IgnΓ‘cio ZM et al. | β | 2014 | β |
| Establishment of the method for screening the potential targets and effective components of huatuo reconstruction pill. | Wu KZ et al. | β | 2014 | β |
| Executive and modulatory neural circuits of defensive reactions: implications for panic disorder. | Canteras NS et al. | β | 2014 | β |
| Functional expression of 5-HTβ· receptor on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice. | Yang EJ et al. | β | 2014 | β |
| Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. | Anastasio NC et al. | β | 2014 | β |
| Genetic variant of AKT1 and AKTIP associated with late-onset depression in a Brazilian population. | Pereira PA et al. | β | 2014 | β |
| Genome-wide association discoveries of alcohol dependence. | Zuo L et al. | β | 2014 | β |
| Glycogen synthase kinase-3 overexpression replicates electroretinogram anomalies of offspring at high genetic risk for schizophrenia and bipolar disorder. | Lavoie J et al. | β | 2014 | β |
| Influence of ghrelin on the central serotonergic signaling system in mice. | Hansson C et al. | β | 2014 | β |
| Inhibition of apomorphine-induced conditioned place preference in rats co-injected with buspirone: relationship with serotonin and dopamine in the striatum. | Haleem DJ et al. | β | 2014 | β |
| Inhibition of native 5-HT3 receptor-evoked contractions in guinea pig and mouse ileum by antimalarial drugs. | Kelley SP et al. | β | 2014 | β |
| Kefir protective effects against nicotine cessation-induced anxiety and cognition impairments in rats. | Noori N et al. | β | 2014 | β |
| Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders. | Khatri N et al. | β | 2014 | β |
| Looking beyond 5-HT(3) receptors: a review of the wider role of serotonin in the pharmacology of nausea and vomiting. | Johnston KD et al. | β | 2014 | β |
| Metabolic kinetics of 5-hydroxytryptamine and the research targets of functional gastrointestinal disorders. | Jing F et al. | β | 2014 | β |
| Modulation of 5-HT7 receptor: effect on object recognition performances in mice. | Freret T et al. | β | 2014 | β |
| Modulation of the subthalamic nucleus activity by serotonergic agents and fluoxetine administration. | Aristieta A et al. | β | 2014 | β |
| Molecular characterization and analysis of a putative 5-HT receptor involved in reproduction process of the pearl oyster Pinctada fucata. | Wang Q et al. | β | 2014 | β |
| Monoamine transporter inhibitors and substrates as treatments for stimulant abuse. | Howell LL et al. | β | 2014 | β |
| Monosodium glutamate, a food additive, induces depressive-like and anxiogenic-like behaviors in young rats. | Quines CB et al. | β | 2014 | β |
| Neuronal localization of the 5-HT2 receptor family in the amygdaloid complex. | Bombardi C | β | 2014 | β |
| Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression. | Kim Y et al. | β | 2014 | β |
| Performance of compulsive behavior in rats is not a unitary phenomenon - validation of separate functional components in compulsive checking behavior. | Tucci MC et al. | β | 2014 | β |
| PET tracers for serotonin receptors and their applications. | Kumar JS et al. | β | 2014 | β |
| Pharmacology of serotonin and female sexual behavior. | Uphouse L | β | 2014 | β |
| Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem. | Kim JY et al. | β | 2014 | β |
| Prothrombotic platelet phenotype in major depression: downregulation by antidepressant treatment. | Lopez-Vilchez I et al. | β | 2014 | β |
| Receptor-ligand interaction at 5-HT3 serotonin receptors: a cluster approach. | Rao BK et al. | β | 2014 | β |
| Recovery of neuronal and network excitability after spinal cord injury and implications for spasticity. | D'Amico JM et al. | β | 2014 | β |
| Role(s) of the 5-HT2C receptor in the development of maximal dentate activation in the hippocampus of anesthetized rats. | Orban G et al. | β | 2014 | β |
| Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status. | Ramirez MJ et al. | β | 2014 | β |
| Serotonin and the search for the anatomical substrate of aggression. | Alekseyenko OV et al. | β | 2014 | β |
| Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction. | Cunningham KA et al. | β | 2014 | β |
| Serotonin modulates electrosensory processing and behavior via 5-HT2-like receptors. | Larson EA et al. | β | 2014 | β |
| Sevoflurane induced amnesia inhibits hippocampal Arc expression partially through 5-hydroxytryptamine-7 receptors in the bilateral basolateral amygdala in rats. | Zhang F et al. | β | 2014 | β |
| Spinal 5-HTβ A receptors mediate 5-HT-induced antinociception in several pain models in rats. | MuΓ±oz-Islas E et al. | β | 2014 | β |
| Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands. | Kumar JSD et al. | β | 2014 | β |
| Synthesis and in vitro pharmacological evaluation of novel 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands. | Fiorino F et al. | β | 2014 | β |
| Targeting the modulation of neural circuitry for the treatment of anxiety disorders. | Farb DH et al. | β | 2014 | β |
| The capsaicin analog nonivamide decreases total energy intake from a standardized breakfast and enhances plasma serotonin levels in moderately overweight men after administered in an oral glucose tolerance test: a randomized, crossover trial. | Hochkogler CM et al. | β | 2014 | β |
| The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic. | Paul ED et al. | β | 2014 | β |
| The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus. | Javid FA et al. | β | 2014 | β |
| The effect of the 5-HT7 serotonin receptor agonist, LP44, on micturition in rats with chronic spinal cord injury. | Gang W et al. | β | 2014 | β |
| The role of serotonin in memory: interactions with neurotransmitters and downstream signaling. | Seyedabadi M et al. | β | 2014 | β |
| Yokukansan, a traditional Japanese herbal medicine, alleviates the emotional abnormality induced by maladaptation to stress in mice. | Tsuji M et al. | β | 2014 | β |
| 5-HT1A and 5-HT2A receptor control of a panic-like defensive response in the rat dorsomedial hypothalamic nucleus. | de Bortoli VC et al. | β | 2013 | β |
| 5-HT depletion, but not 5-HT1A antagonist, prevents the anxiolytic-like effect of citalopram in rat contextual conditioned fear stress model. | Masuda T et al. | β | 2013 | β |
| A linear combination of pharmacophore hypotheses as a new tool in search of new active compounds--an application for 5-HT1A receptor ligands. | Warszycki D et al. | β | 2013 | β |
| Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue. | Klotz JL et al. | β | 2013 | β |
| Antidepressants and anti-inflammatory drugs differentially reduce the release of NGF and BDNF from rat platelets. | Hochstrasser T et al. | β | 2013 | β |
| Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists. | Kim J et al. | β | 2013 | β |
| Association between 5-HT2A receptor polymorphisms and risk of obstructive sleep apnea and hypopnea syndrome: a systematic review and meta-analysis. | Zhao Y et al. | β | 2013 | β |
| Association between serotonin transporter gene polymorphisms and childhood asthma. | Farjadian S et al. | β | 2013 | β |
| Association of temporomandibular dysfunction with the 102T-C polymorphism in the serotonin receptor gene in Brazilian patients. | de Freitas LV et al. | β | 2013 | β |
| Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith-Lemli-Opitz syndrome. | Korade Z et al. | β | 2013 | β |
| Central 5-HT1A receptor-mediated modulation of heart rate dynamics and its adjustment by conditioned and unconditioned fear in mice. | Youn J et al. | β | 2013 | β |
| Comodulation of dopamine and serotonin on prefrontal cortical rhythms: a theoretical study. | Wang DH et al. | β | 2013 | β |
| Comparison of female Fischer and Sprague-Dawley rats in the response to ketanserin. | Miryala CS et al. | β | 2013 | β |
| Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. | Fox JH et al. | β | 2013 | β |
| Crosstalk between contact hypersensitivity reaction and antidepressant drugs. | Curzytek K et al. | β | 2013 | β |
| Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT(7) ligands and role of the aromatic substituents in binding to the target receptor. | Kim Y et al. | β | 2013 | β |
| Does pharmacogenomics account for variability in control of acute chemotherapy-induced nausea and vomiting with 5-hydroxytryptamine type 3 receptor antagonists? | Trammel M et al. | β | 2013 | β |
| Elevated Expression of Serotonin 5-HT(2A) Receptors in the Rat Ventral Tegmental Area Enhances Vulnerability to the Behavioral Effects of Cocaine. | Herin DV et al. | β | 2013 | β |
| Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data. | Hulin A et al. | β | 2013 | β |
| Endocannabinoids blunt the augmentation of synaptic transmission by serotonin 2A receptors in the nucleus tractus solitarii (nTS). | Austgen JR et al. | β | 2013 | β |
| Evidence for the participation of peripheral 5-HTβA, 5-HTβB, and 5-HTβC receptors in formalin-induced secondary mechanical allodynia and hyperalgesia. | Cervantes-DurΓ‘n C et al. | β | 2013 | β |
| Exercise benefits brain function: the monoamine connection. | Lin TW et al. | β | 2013 | β |
| Extending therapeutic use of psychostimulants: focus on serotonin-1A receptor. | Haleem DJ | β | 2013 | β |
| From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists. | Higgins GA et al. | β | 2013 | β |
| Functional anatomy of 5-HT2A receptors in the amygdala and hippocampal complex: relevance to memory functions. | Bombardi C et al. | β | 2013 | β |
| Functional topography of serotonergic systems supports the Deakin/Graeff hypothesis of anxiety and affective disorders. | Paul ED et al. | β | 2013 | β |
| Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis. | Snir O et al. | β | 2013 | β |
| HDAC inhibitor DWP0016 activates p53 transcription and acetylation to inhibit cell growth in U251 glioblastoma cells. | Jin H et al. | β | 2013 | β |
| HTR4 gene structure and altered expression in the developing lung. | Hodge E et al. | β | 2013 | β |
| Human 5-HTβreceptor stimulation in atria of transgenic mice. | Gergs U et al. | β | 2013 | β |
| Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. | Zaldivar A et al. | β | 2013 | β |
| Investigating gene expression differences in two chicken groups with variable propensity to feather pecking. | Wysocki M et al. | β | 2013 | β |
| Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels. | Maejima T et al. | β | 2013 | β |
| Neuromodulation of early electrosensory processing in gymnotiform weakly electric fish. | MΓ‘rquez BT et al. | β | 2013 | β |
| Neurotransmitters and synaptic components in the Merkel cell-neurite complex, a gentle-touch receptor. | Maksimovic S et al. | β | 2013 | β |
| Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity. | Yang HY et al. | β | 2013 | β |
| Perinatal exposure to bisphenol A enhances contextual fear memory and affects the serotoninergic system in juvenile female mice. | Matsuda S et al. | β | 2013 | β |
| Pharmacological characterization of a 5-HT1-type serotonin receptor in the red flour beetle, Tribolium castaneum. | Vleugels R et al. | β | 2013 | β |
| Preclinical models of antipsychotic drug action. | Moreno JL et al. | β | 2013 | β |
| Role of serotonin 1A receptors in the median raphe nucleus on the behavioral consequences of forced swim stress. | Almeida PV et al. | β | 2013 | β |
| Sensitive profiling of biogenic amines in human urine by capillary electrophoresis with field amplified sample injection. | Bacaloni A et al. | β | 2013 | β |
| Serotonergic genes and suicide: a systematic review. | Antypa N et al. | β | 2013 | β |
| Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease. | Navailles S et al. | β | 2013 | β |
| Serotonin2C Receptors and the Motor Control of Oral Activity. | LagiΓ¨re M et al. | β | 2013 | β |
| Serotonin: a novel bone mass controller may have implications for alveolar bone. | Galli C et al. | β | 2013 | β |
| Serotonin directly stimulates cortisol secretion from the interrenals in goldfish. | Lim JE et al. | β | 2013 | β |
| Serotonin discovery and stepwise disclosure of 5-HT receptor complexity over four decades. Part I. General background and discovery of serotonin as a basis for 5-HT receptor identification. | GΓΆthert M | β | 2013 | β |
| Serotonin homeostasis and serotonin receptors as actors of cortical construction: special attention to the 5-HT3A and 5-HT6 receptor subtypes. | Vitalis T et al. | β | 2013 | β |
| Serotonin receptor of type 6 (5-HT6) in human prefrontal cortex and hippocampus post-mortem: an immunohistochemical and immunofluorescence study. | Marazziti D et al. | β | 2013 | β |
| Serotonin signalling in the gut--functions, dysfunctions and therapeutic targets. | Mawe GM et al. | β | 2013 | β |
| Serotonin skews human macrophage polarization through HTR2B and HTR7. | de las Casas-Engel M et al. | β | 2013 | β |
| Spasmolytic effect of caulerpine involves blockade of CaΒ²βΊ influx on guinea pig ileum. | Cavalcante-Silva LH et al. | β | 2013 | β |
| Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors. | Isberg V et al. | β | 2013 | β |
| Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. | Cunningham KA et al. | β | 2013 | β |
| Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates. | Majo VJ et al. | β | 2013 | β |
| Systematic identification of proteins that elicit drug side effects. | Kuhn M et al. | β | 2013 | β |
| The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling. | Atanes P et al. | β | 2013 | β |
| The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. | Alexander SP et al. | β | 2013 | β |
| The effects of combining serotonin reuptake inhibition and 5-HT7 receptor blockade on circadian rhythm regulation in rodents. | Westrich L et al. | β | 2013 | β |
| The neurobiology of oppositional defiant disorder and conduct disorder: altered functioning in three mental domains. | Matthys W et al. | β | 2013 | β |
| The role of galanin system in modulating depression, anxiety, and addiction-like behaviors after chronic restraint stress. | Zhao X et al. | β | 2013 | β |
| Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters. | Lacivita E et al. | β | 2013 | β |
| Vasoactive intestinal polypeptide regulates barrier function via mast cells in human intestinal follicle-associated epithelium and during stress in rats. | Keita AV et al. | β | 2013 | β |
| Vasopressin-induced constriction of the isolated rat occipital artery is segment dependent. | Chelko SP et al. | β | 2013 | β |
| Verbal memory deficits are correlated with prefrontal hypometabolism in (18)FDG PET of recreational MDMA users. | Bosch OG et al. | β | 2013 | β |
| 4-Aminoethylpiperazinyl aryl ketones with 5-HTβA/5-HTβ selectivity. | Kim MK et al. | β | 2012 | β |
| 5-HIAA excretion is not associated with bone metabolism in carcinoid syndrome patients. | van Dijk SC et al. | β | 2012 | β |
| 5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. | Pitychoutis PM et al. | β | 2012 | β |
| 5-HT1A and 5-HT7 receptor crosstalk in the regulation of emotional memory: implications for effects of selective serotonin reuptake inhibitors. | Eriksson TM et al. | β | 2012 | β |
| 5-HT(2A) receptor activation in the dorsolateral septum facilitates inhibitory avoidance in the elevated T-maze. | de Paula DC et al. | β | 2012 | β |
| 5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen. | Pockros LA et al. | β | 2012 | β |
| 5-HT(3) receptors. | Lummis SC | β | 2012 | β |
| 5-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner. | Kobe F et al. | β | 2012 | β |
| 5-HT receptors as novel targets for optimizing pigmentary responses in dorsal skin melanophores of frog, Hoplobatrachus tigerinus. | Ali SA et al. | β | 2012 | β |
| 5-Hydroxytryptamine initiates pulsatile urea excretion from perfused gills of the gulf toadfish (Opsanus beta). | McDonald MD et al. | β | 2012 | β |
| Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome. | Costa L et al. | β | 2012 | β |
| Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity. | Hoffman JM et al. | β | 2012 | β |
| Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus. | Tokarski K et al. | β | 2012 | β |
| Alterations in serotonin receptor-induced contractility of bovine lateral saphenous vein in cattle grazing endophyte-infected tall fescue. | Klotz JL et al. | β | 2012 | β |
| A novel mechanism for regulating hepatic glycogen synthesis involving serotonin and cyclin-dependent kinase-5. | Tudhope SJ et al. | β | 2012 | β |
| A role for 5-HT1A receptors in the basolateral amygdala in the development of conditioned defeat in Syrian hamsters. | Morrison KE et al. | β | 2012 | β |
| A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health. | Beaulieu JM | β | 2012 | β |
| Cloning and expression of a zebrafish 5-HT(2C) receptor gene. | Schneider H et al. | β | 2012 | β |
| Design of novel quinazolinone derivatives as inhibitors for 5HT7 receptor. | Chitta A et al. | β | 2012 | β |
| Development and validation of quantitative structure-activity relationship models for compounds acting on serotoninergic receptors. | Zydek G et al. | β | 2012 | β |
| Differential respiratory control of the upper airway and diaphragm muscles induced by 5-HT1A receptor ligands. | Besnard S et al. | β | 2012 | β |
| Editing of neurotransmitter receptor and ion channel RNAs in the nervous system. | Hood JL et al. | β | 2012 | β |
| Effect of antiserotonin drug on the development of lung fibrosis and blood system reactions after intratracheal administration of bleomycin. | Skurikhin EG et al. | β | 2012 | β |
| Effects of chronic lead intoxication on rat serotoninergic system and anxiety behavior. | Sansar W et al. | β | 2012 | β |
| ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior. | Lenz B et al. | β | 2012 | β |
| Fluoxetine (prozac) and serotonin act on excitatory synaptic transmission to suppress single layer 2/3 pyramidal neuron-triggered cell assemblies in the human prefrontal cortex. | KomlΓ³si G et al. | β | 2012 | β |
| From the prodrome to chronic schizophrenia: the neurobiology underlying psychotic symptoms and cognitive impairments. | Howes OD et al. | β | 2012 | β |
| Functional significance of glycogen synthase kinase-3 regulation by serotonin. | Polter AM et al. | β | 2012 | β |
| Genetic biomarkers of depression. | Tamatam A et al. | β | 2012 | β |
| HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. | Asad S et al. | β | 2012 | β |
| Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. | Xie DJ et al. | β | 2012 | β |
| Inhibition of SNL-induced upregulation of CGRP and NPY in the spinal cord and dorsal root ganglia by the 5-HT(2A) receptor antagonist ketanserin in rats. | Wang D et al. | β | 2012 | β |
| Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae. | Chai W et al. | β | 2012 | β |
| Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice. | Adriani W et al. | β | 2012 | β |
| Neuronal localization of 5-HT2A receptor immunoreactivity in the rat hippocampal region. | Bombardi C | β | 2012 | β |
| New potent 5-HT(2A) receptor ligands containing an N'-cyanopicolinamidine nucleus: Synthesis and inΒ vitro pharmacological evaluation. | Fiorino F et al. | β | 2012 | β |
| Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through Ξ²2 receptor. | Masuda T et al. | β | 2012 | β |
| Normative database of the serotonergic system in healthy subjects using multi-tracer PET. | Savli M et al. | β | 2012 | β |
| Novel biochemical manipulation of brain serotonin reveals a role of serotonin in the circadian rhythm of sleep-wake cycles. | Nakamaru-Ogiso E et al. | β | 2012 | β |
| On the presence of serotonin in mammalian cardiomyocytes. | PΓΆnicke K et al. | β | 2012 | β |
| Pharmacological and genetic interventions in serotonin (5-HT)(2C) receptors to alter drug abuse and dependence processes. | Filip M et al. | β | 2012 | β |
| Pharmacology of the new treatments for lower gastrointestinal motility disorders and irritable bowel syndrome. | Camilleri M | β | 2012 | β |
| Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse. | Herman AI et al. | β | 2012 | β |
| Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat. | Huang Y et al. | β | 2012 | β |
| Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disorders. | O'Neil RT et al. | β | 2012 | β |
| Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors. | Seitz PK et al. | β | 2012 | β |
| Radiosynthesis and preclinical evaluation of 18F-F13714 as a fluorinated 5-HT1A receptor agonist radioligand for PET neuroimaging. | Lemoine L et al. | β | 2012 | β |
| Recent advances in the pathogenesis and clinical evaluation of pulmonary fibrosis. | Margaritopoulos GA et al. | β | 2012 | β |
| Regulation of central noradrenergic activity by 5-HT(3) receptors located in the locus coeruleus of the rat. | Ortega JE et al. | β | 2012 | β |
| Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors. | Aira Z et al. | β | 2012 | β |
| Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system. | Slominski AT et al. | β | 2012 | β |
| Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration. | Vicente MA et al. | β | 2012 | β |
| Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior. | Yoshimoto K et al. | β | 2012 | β |
| Serotonin 5-HT(1A) receptor binding sites in the brain of the pigeon (Columba livia). | Herold C et al. | β | 2012 | β |
| Serotonin (5-HT7) receptor-stimulated activation of cAMP-PKA pathway in bovine corneal epithelial and endothelial cells. | Grueb M et al. | β | 2012 | β |
| Serotonin: a double-edged sword for the liver? | Lesurtel M et al. | β | 2012 | β |
| Serotonin and blood pressure regulation. | Watts SW et al. | β | 2012 | β |
| Serotonin and ionizing radiation synergistically affect proliferation and adhesion molecule expression of malignant melanoma cells. | MΓΌller K et al. | β | 2012 | β |
| Serotonin and synaptic transmission at invertebrate neuromuscular junctions. | Wu WH et al. | β | 2012 | β |
| Serotonin-immunoreactive neurons and mast cells in the mouse esophagus suggest involvement of serotonin in both motility control and neuroimmune interactions. | Hempfling C et al. | β | 2012 | β |
| Serotonin modulates the population activity profile of olfactory bulb external tufted cells. | Liu S et al. | β | 2012 | β |
| Serotonin receptors in hippocampus. | Berumen LC et al. | β | 2012 | β |
| Serotonin transporter activity of imidazolidine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives in aspect of their acid-base properties. | ZagΓ³rska A et al. | β | 2012 | β |
| Sphingolipid-binding domain in the serotonin(1A) receptor. | Chattopadhyay A et al. | β | 2012 | β |
| Stress- and antidepressant treatment-induced modifications of 5-HTβ receptor functions in the rat brain. | Tokarski K et al. | β | 2012 | β |
| Subchronic treatment with fluoxetine and ketanserin increases hippocampal brain-derived neurotrophic factor, Ξ²-catenin and antidepressant-like effects. | Pilar-CuΓ©llar F et al. | β | 2012 | β |
| Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice. | Freret T et al. | β | 2012 | β |
| Synthesis and biological evaluation of benzoisothiazole derivatives possessing N,N-dimethylformimidamide group as 5-HTβ receptor antagonists. | Yoo E et al. | β | 2012 | β |
| Synthesis and pharmacological evaluation of [(4-arylpiperazin-1-yl)-alkyl]-carbamic acid ethyl ester derivatives as potential anxiolytic agents. | Khatri M et al. | β | 2012 | β |
| The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. | Higgins GA et al. | β | 2012 | β |
| The 5-HT(7) receptor in learning and memory. | Roberts AJ et al. | β | 2012 | β |
| The adverse skeletal effects of selective serotonin reuptake inhibitors. | Tsapakis EM et al. | β | 2012 | β |
| The anxiogenic-like effects of dehydration in a semi-desert rodent Meriones shawi indicating the possible involvement of the serotoninergic system. | Elgot A et al. | β | 2012 | β |
| The serotonergic system in ageing and Alzheimer's disease. | RodrΓguez JJ et al. | β | 2012 | β |
| The serotonin 2C receptor antagonist SB 242084 exhibits abuse-related effects typical of stimulants in squirrel monkeys. | Manvich DF et al. | β | 2012 | β |
| The therapeutic potential of 5-HT1A receptors: a patent review. | Lacivita E et al. | β | 2012 | β |
| Transcript diversification in the nervous system: a to I RNA editing in CNS function and disease development. | Tariq A et al. | β | 2012 | β |
| Twenty-five lessons from computational neuromodulation. | Dayan P | β | 2012 | β |
| Vasoconstrictor and vasodilator responses to tryptamine of rat-isolated perfused mesentery: comparison with tyramine and Ξ²-phenylethylamine. | Anwar MA et al. | β | 2012 | β |
| Zebrafish: a model for the study of addiction genetics. | Klee EW et al. | β | 2012 | β |
| 5-HT receptors and reward-related behaviour: a review. | Hayes DJ et al. | β | 2011 | β |
| 5-HT receptors mediate lineage-dependent effects of serotonin on adult neurogenesis in Procambarus clarkii. | Zhang Y et al. | β | 2011 | β |
| 5-hydroxtryptamine receptors in systemic hypertension: an arterial focus. | Watts SW et al. | β | 2011 | β |
| 5-hydroxytryptamine generates tonic inward currents on pacemaker activity of interstitial cells of cajal from mouse small intestine. | Shahi PK et al. | β | 2011 | β |
| 5-Hydroxytryptamine potentiates neurogenic contractions of rat isolated urinary bladder through both 5-HT(7) and 5-HT(2C) receptors. | Rekik M et al. | β | 2011 | β |
| Adipocytes express a functional system for serotonin synthesis, reuptake and receptor activation. | Stunes AK et al. | β | 2011 | β |
| Antagonism of 5-HT(2A) receptors inhibits the expression of pronociceptive mediator and enhances endogenous opioid mechanism in carrageenan-induced inflammation in rats. | Huang J et al. | β | 2011 | β |
| Antagonist interaction with the human 5-HT(7) receptor mediates the rapid and potent inhibition of non-G-protein-stimulated adenylate cyclase activity: a novel GPCR effect. | Klein MT et al. | β | 2011 | β |
| Association of 5-hydroxytryptamine (serotonin) receptor 4 (5-HTR4) gene polymorphisms with asthma. | Kim TH et al. | β | 2011 | β |
| Attenuation of 1-(m-chlorophenyl)-biguanide induced hippocampus-dependent memory impairment by a standardised extract of Bacopa monniera (BESEB CDRI-08). | Rajan KE et al. | β | 2011 | β |
| Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats. | Haleem DJ | β | 2011 | β |
| Biogenic monoamines in preimplantation development. | Cikos S et al. | β | 2011 | β |
| Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. | Scopinho AA et al. | β | 2011 | β |
| Central 5-HT3 receptor-induced hypothermia is associated with reduced metabolic rate and increased heat loss. | Voronova IP et al. | β | 2011 | β |
| Changes in plasma and platelet BDNF levels induced by S-citalopram in major depression. | Serra-MillΓ s M et al. | β | 2011 | β |
| Classification of 5-HT(1A) receptor agonists and antagonists using GA-SVM method. | Zhu XL et al. | β | 2011 | β |
| Combination of escitalopram and a 5-HT(βA) receptor antagonist selectively decreases the extracellular levels of dopamine in the nucleus accumbens relative to striatum through 5-HT(βC) receptor stimulation; suggestive of antipsychotic potential. | HovelsΓΈ N et al. | β | 2011 | β |
| Context-dependent modulation of auditory processing by serotonin. | Hurley LM et al. | β | 2011 | β |
| Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease. | Lai MK et al. | β | 2011 | β |
| Distinct regulation of mitochondrial localization and stability of two human Sirt5 isoforms. | Matsushita N et al. | β | 2011 | β |
| Distribution of 5-HT2A receptor immunoreactivity in the rat amygdaloid complex and colocalization with Ξ³-aminobutyric acid. | Bombardi C | β | 2011 | β |
| Drug-induced changes in cortical inhibition in medication overuse headache. | CurrΓ A et al. | β | 2011 | β |
| Effect of fluvoxamine on carrageenan-induced paw edema in rats evaluation of the action sites. | Hajhashemi V et al. | β | 2011 | β |
| Effects of 5-hydroxytryptamine on substantia gelatinosa neurons of the trigeminal subnucleus caudalis in immature mice. | Yin H et al. | β | 2011 | β |
| Emerging drugs for schizophrenia. | Biedermann F et al. | β | 2011 | β |
| Enamel alterations in serotonin 2B receptor knockout mice. | Harichane Y et al. | β | 2011 | β |
| Epigenetics in Developmental Disorder: ADHD and Endophenotypes. | Archer T et al. | β | 2011 | β |
| Experimental examination of anti-inflammatory effects of a 5-HT3 receptor antagonist, tropisetron, and concomitant effects on autonomic nervous function in a rat sepsis model. | Setoguchi D et al. | β | 2011 | β |
| Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network. | Niebert M et al. | β | 2011 | β |
| GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors. | Shrivastava AN et al. | β | 2011 | β |
| Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. | Zlojutro M et al. | β | 2011 | β |
| Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission. | Polter AM et al. | β | 2011 | β |
| G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations. | Isberg V et al. | β | 2011 | β |
| Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice. | Amireault P et al. | β | 2011 | β |
| Involvement of dorsal raphe nucleus and dorsal periaqueductal gray 5-HT receptors in the modulation of mouse defensive behaviors. | Pobbe RL et al. | β | 2011 | β |
| Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. | Murray KC et al. | β | 2011 | β |
| New treatment options for chronic constipation: mechanisms, efficacy and safety. | Camilleri M | β | 2011 | β |
| Normal and reversed phase thin layer chromatography data in quantitative structure-activity relationship study of compounds with affinity for serotonin (5-HT) receptors. | Zydek G et al. | β | 2011 | β |
| Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases. | Walther DJ et al. | β | 2011 | β |
| Opponency revisited: competition and cooperation between dopamine and serotonin. | Boureau YL et al. | β | 2011 | β |
| Peripheral 5-HT1B and 5-HT2A receptors mediate the nociceptive response induced by 5-hydroxytryptamine in mice. | Nascimento EB et al. | β | 2011 | β |
| Pharmacologic management of postoperative nausea and vomiting. | Fero KE et al. | β | 2011 | β |
| Prefrontal cortex and drug abuse vulnerability: translation to prevention and treatment interventions. | Perry JL et al. | β | 2011 | β |
| Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain. | Bose SK et al. | β | 2011 | β |
| Presynaptic control of serotonin on striatal dopamine function. | Navailles S et al. | β | 2011 | β |
| Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain. | VarnΓ€s K et al. | β | 2011 | β |
| Raphe-Hippocampal Serotonin Neurotransmission In The Sex Related Differences of Adaptation to Stress: Focus on Serotonin-1A Receptor. | Jabeen Haleem D | β | 2011 | β |
| Reduced placental vascular reactivity to 5-hydroxytryptamine in pre-eclampsia and the status of 5HT(2A) receptors. | Ugun-Klusek A et al. | β | 2011 | β |
| Reduced ventral striatal/ventral pallidal serotonin1B receptor binding potential in major depressive disorder. | Murrough JW et al. | β | 2011 | β |
| Risperidone-induced inactivation and clozapine-induced reactivation of rat cortical astrocyte 5-hydroxytryptamineβ receptors: evidence for in situ G protein-coupled receptor homodimer protomer cross-talk. | Smith C et al. | β | 2011 | β |
| Role of central serotonin and melanocortin systems in the control of energy balance. | Marston OJ et al. | β | 2011 | β |
| Role of peripheral serotonin in glucose and lipid metabolism. | Watanabe H et al. | β | 2011 | β |
| Selective serotonin reuptake inhibitors (SSRIs) and heart defects: potential mechanisms for the observed associations. | Sadler TW | β | 2011 | β |
| Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [ΒΉΒΉC]dasb and [ΒΉΒΉC]WAY100635 in young healthy men. | Takano H et al. | β | 2011 | β |
| Serotonin-2A receptor regulation of panic-like behavior in the rat dorsal periaqueductal gray matter: the role of GABA. | de Oliveira Sergio T et al. | β | 2011 | β |
| Serotonin activates MAP kinase and PI3K/Akt signaling pathways in prostate cancer cell lines. | Dizeyi N et al. | β | 2011 | β |
| [Serotonin receptor 1A-modulated dephosphorylation of glycine receptor Ξ±3: a new molecular mechanism of breathing control for compensation of opioid-induced respiratory depression without loss of analgesia]. | Manzke T et al. | β | 2011 | β |
| Serotonin receptor 5-HT2B mediates serotonin-induced mechanical hyperalgesia. | Lin SY et al. | β | 2011 | β |
| Serotonin receptors - from molecular biology to clinical applications. | Pytliak M et al. | β | 2011 | β |
| Synthesis and biological evaluation of potential 5-HT(7) receptor PET radiotracers. | Andries J et al. | β | 2011 | β |
| Synthesis and evaluation of dimeric derivatives of 5-HT(2A) receptor (5-HT(2A)R) antagonist M-100907. | Shashack MJ et al. | β | 2011 | β |
| Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. | Fiorino F et al. | β | 2011 | β |
| The involvement of the serotonergic transmission system in neonatal and adult rat ileum contractility varies with age. | Lobo SB et al. | β | 2011 | β |
| Therapeutics of 5-HT3 receptor antagonists: current uses and future directions. | Machu TK | β | 2011 | β |
| The serotonergic system in Parkinson's disease. | Huot P et al. | β | 2011 | β |
| The use of serotonergic drugs to treat obesity--is there any hope? | Bello NT et al. | β | 2011 | β |
| Time-dependent modulation of serotonin and its receptors 1A and 2A expression in allergic contact dermatitis. | Wetterberg J et al. | β | 2011 | β |
| Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships. | Klein MT et al. | β | 2011 | β |
| Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus. | Bernhardt V et al. | β | 2011 | β |
| Tracheal occlusion modulates the gene expression profile of the medial thalamus in anesthetized rats. | Bernhardt V et al. | β | 2011 | β |
| [18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging. | Lemoine L et al. | β | 2010 | β |
| 5-HT1A and 5-HT1B receptors differentially modulate rate and timing of auditory responses in the mouse inferior colliculus. | Ramsey LC et al. | β | 2010 | β |
| 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. | Foong JP et al. | β | 2010 | β |
| 5-HTβ antagonists under development. | Chong Y et al. | β | 2010 | β |
| 5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes. | Derangeon M et al. | β | 2010 | β |
| 5-hydroxytryptamine subtype 6 receptor modulators: a patent survey. | Ivachtchenko AV et al. | β | 2010 | β |
| Acute lecozotan administration increases learning and memory in rats without affecting anxiety or behavioral depression. | Skirzewski M et al. | β | 2010 | β |
| Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus. | ValdizΓ‘n EM et al. | β | 2010 | β |
| A new perspective on auxin perception. | Shishova M et al. | β | 2010 | β |
| Central serotonin 1A receptor binding in temporal lobe epilepsy: a [carbonyl-(11)C]WAY-100635 PET study. | Assem-Hilger E et al. | β | 2010 | β |
| Chiral aryloxyalkylamines: Selective 5-HT(1B/1D) activation and analgesic activity. | Carocci A et al. | β | 2010 | β |
| Cyclic AMP signaling in bivalve molluscs: an overview. | Fabbri E et al. | β | 2010 | β |
| De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist. | Nugiel DA et al. | β | 2010 | β |
| Different serotonergic expression in nevomelanocytic tumors. | Naimi-Akbar C et al. | β | 2010 | β |
| Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis. | Xiong Y et al. | β | 2010 | β |
| Endogenous serotonin acts on 5-HT2C-like receptors in key vocal areas of the brain stem to initiate vocalizations in Xenopus laevis. | Yu HJ et al. | β | 2010 | β |
| Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis. | Seddighzadeh M et al. | β | 2010 | β |
| Hearing loss alters serotonergic modulation of intrinsic excitability in auditory cortex. | Rao D et al. | β | 2010 | β |
| High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943. | Nabulsi N et al. | β | 2010 | β |
| Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by Ξ²-phenylethylamine. | Fehler M et al. | β | 2010 | β |
| Impact of serotonin receptor 2A gene haplotypes on C-peptide levels in clozapine- and olanzapine-treated patients. | Melkersson KI et al. | β | 2010 | β |
| Infrared spectra of protonated neurotransmitters: serotonin. | Lagutschenkov A et al. | β | 2010 | β |
| Inverse agonist and neutral antagonist actions of synthetic compounds at an insect 5-HT1 receptor. | Troppmann B et al. | β | 2010 | β |
| Involvement of 5-hydroxytryptamine type 3 receptors in sevoflurane-induced hypnotic and analgesic effects in mice. | Hang LH et al. | β | 2010 | β |
| Kinetic modeling of the serotonin 5-HT(1B) receptor radioligand [(11)C]P943 in humans. | Gallezot JD et al. | β | 2010 | β |
| Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. | Fouad K et al. | β | 2010 | β |
| Membrane cholesterol in the function and organization of G-protein coupled receptors. | Paila YD et al. | β | 2010 | β |
| Modulatory role of serotonin on feeding behavior. | MagalhΓ£es CP et al. | β | 2010 | β |
| Neuromediators in inflammation--a macrophage/nerve connection. | Ley S et al. | β | 2010 | β |
| New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: synthesis and in vitro pharmacological evaluation. | Fiorino F et al. | β | 2010 | β |
| New-generation 5-HT4 receptor agonists: potential for treatment of gastrointestinal motility disorders. | Manabe N et al. | β | 2010 | β |
| One-pot synthesis of new substituted 1,2,3,4-tetrahydrocarbazoles via Petasis reaction. | Neogi S et al. | β | 2010 | β |
| Pharmacological targets for pulmonary vascular disease: vasodilation versus anti-remodelling. | Thomas M | β | 2010 | β |
| Pharmacophore-based 3D QSAR studies on a series of high affinity 5-HT1A receptor ligands. | Weber KC et al. | β | 2010 | β |
| Phe369(7.38) at human 5-HT(7) receptors confers interspecies selectivity to antagonists and partial agonists. | Varin T et al. | β | 2010 | β |
| Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy. | Schraenen A et al. | β | 2010 | β |
| Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis. | Guo JD et al. | β | 2010 | β |
| Pulsatile GnRH secretion: roles of G protein-coupled receptors, second messengers and ion channels. | Krsmanovic LZ et al. | β | 2010 | β |
| Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. | Murray KC et al. | β | 2010 | β |
| Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats. | Vidal R et al. | β | 2010 | β |
| Role of serotonin in central dopamine dysfunction. | Di Giovanni G et al. | β | 2010 | β |
| Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease. | Carta M et al. | β | 2010 | β |
| Roles of serotonin 5-HT3 receptor in the formation of dendrites and axons in the rat cerebral cortex: an in vitro study. | Hayashi T et al. | β | 2010 | β |
| Selective inhibition of 5-HT7 receptor reduces CGRP release in an experimental model for migraine. | Wang X et al. | β | 2010 | β |
| Serotonin and fluoxetine receptors are expressed in enamel organs and LS8 cells and modulate gene expression in LS8 cells. | Riksen EA et al. | β | 2010 | β |
| Serotonin and its 5-HT(2) receptor agonist DOI hydrochloride inhibit the oxidative burst in total leukocytes but not in isolated neutrophils. | PracharovΓ‘ L et al. | β | 2010 | β |
| Serotoninergic fine-tuning of the excitation-inhibition balance in rat visual cortical networks. | Moreau AW et al. | β | 2010 | β |
| Serotonin modulates glutamatergic transmission in the rat olfactory tubercle. | Hadley JK et al. | β | 2010 | β |
| Serotonin receptor 1A-modulated phosphorylation of glycine receptor Ξ±3 controls breathing in mice. | Manzke T et al. | β | 2010 | β |
| Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats. | Silveira JW et al. | β | 2010 | β |
| Significant association between the C(-1019)G functional polymorphism of the HTR1A gene and impulsivity. | Benko A et al. | β | 2010 | β |
| Simultaneous tritium labelling of two potent 5-HT4 ligands. | Sobrio F et al. | β | 2010 | β |
| Subtype-specific changes in 5-HT receptor-mediated modulation of C fibre-evoked spinal field potentials are triggered by peripheral nerve injury. | Aira Z et al. | β | 2010 | β |
| Synthesis and pharmacological evaluation of novel fused thiophene derivatives as 5-HT2A receptor antagonists: molecular modeling study. | El-Kerdawy MM et al. | β | 2010 | β |
| The 5-HT 2A serotonin receptor enhances cell viability, affects cell cycle progression and activates MEK-ERK1/2 and JAK2-STAT3 signalling pathways in human choriocarcinoma cell lines. | Oufkir T et al. | β | 2010 | β |
| The auspicious role of the 5-HT3 receptor in depression: a probable neuronal target? | Rajkumar R et al. | β | 2010 | β |
| The role in spawning of a putative serotonin receptor isolated from the germ and ciliary cells of the gonoduct in the gonad of the Japanese scallop, Patinopecten yessoensis. | Tanabe T et al. | β | 2010 | β |
| The role of serotonin in the enhancement of long-term memory resulting from predator detection in Lymnaea. | Il-Han J et al. | β | 2010 | β |
| The serotonin subtype 1A receptor regulates cortisol secretion in the Gulf toadfish, Opsanus beta. | Medeiros LR et al. | β | 2010 | β |
| Time-course of 5-HT(6) receptor mRNA expression during memory consolidation and amnesia. | Huerta-Rivas A et al. | β | 2010 | β |
| Topical and systemic administrations of ketanserin attenuate hypersensitivity and expression of CGRP in rats with spinal nerve ligation. | Wang D et al. | β | 2010 | β |
| WAY100635 blocks the hypophagia induced by 8-OH-DPAT in the hypothalamic nuclei. | Steffens SM et al. | β | 2010 | β |
| 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. | Freitas RL et al. | β | 2009 | β |
| 5-HT(1A) and NMDA receptors interact in the rat medial septum and modulate hippocampal-dependent spatial learning. | Elvander-Tottie E et al. | β | 2009 | β |
| 5-HT(1A) receptor function in major depressive disorder. | Savitz J et al. | β | 2009 | β |
| 5-HT antagonists NAN-190 and SB 269970 block alpha2-adrenoceptors in the guinea pig. | Foong JP et al. | β | 2009 | β |
| 5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus. | Hisadome K et al. | β | 2009 | β |
| 5-Hydroxytryptamine2A receptor binding activity of compounds from Litsea sessilis. | Chung LY et al. | β | 2009 | β |
| 5-hydroxytryptamine induced relaxation in the pig urinary bladder neck. | Recio P et al. | β | 2009 | β |
| 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. | MΓΌller T et al. | β | 2009 | β |
| Affect-related behaviors in mice misexpressing the RNA editing enzyme ADAR2. | Singh M et al. | β | 2009 | β |
| Aggression is related to frontal serotonin-1A receptor distribution as revealed by PET in healthy subjects. | Witte AV et al. | β | 2009 | β |
| [A new pharmacological strategy for schizophrenia: the partial agonists of D2 dopaminergic receptors. The principle characteristics of aripiprazole]. | Costentin J | β | 2009 | β |
| Application of desirability-based multi(bi)-objective optimization in the design of selective arylpiperazine derivates for the 5-HT1A serotonin receptor. | Machado A et al. | β | 2009 | β |
| Are specific nonannular cholesterol binding sites present in G-protein coupled receptors? | Paila YD et al. | β | 2009 | β |
| Association between the use of serotonin receptor 2A-blocking antidepressants and joint disorders. | Kling A et al. | β | 2009 | β |
| Bi-directional modulation of bed nucleus of stria terminalis neurons by 5-HT: molecular expression and functional properties of excitatory 5-HT receptor subtypes. | Guo JD et al. | β | 2009 | β |
| Bidirectional modulation of classical fear conditioning in mice by 5-HT(1A) receptor ligands with contrasting intrinsic activities. | Youn J et al. | β | 2009 | β |
| Blockade of 5-HT2A receptors suppresses hyperthermic but not cardiovascular responses to psychosocial stress in rats. | Beig MI et al. | β | 2009 | β |
| Brain creatine kinase activity is increased by chronic administration of paroxetine. | Santos PM et al. | β | 2009 | β |
| Central 5-HT receptors in cardiovascular control during stress. | Nalivaiko E et al. | β | 2009 | β |
| Characterization of serotonin receptors in pregnant human myometrium. | Cordeaux Y et al. | β | 2009 | β |
| Characterization of the naturally occurring Arg344His variant of the human 5-HT 3A receptor. | Combrink S et al. | β | 2009 | β |
| Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice. | Fletcher PJ et al. | β | 2009 | β |
| Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation. | Asada M et al. | β | 2009 | β |
| Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. | Schaffhauser H et al. | β | 2009 | β |
| Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine. | Leventopoulos M et al. | β | 2009 | β |
| Effects of serotonergic agents on survival and hemolymph composition of the larval mosquito Aedes aegypti (Diptera: Culicidae, L.) in vivo: does serotonin regulate hemolymph acid-base homeostasis? | Clark TM et al. | β | 2009 | β |
| Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. | Watakabe A et al. | β | 2009 | β |
| Evidence for a re-evaluation of the neurochemical and anatomical bases of chemotherapy-induced vomiting. | Darmani NA et al. | β | 2009 | β |
| Expression and function of 5-HT7 receptors in smooth muscle preparations from equine duodenum, ileum, and pelvic flexure. | Prause AS et al. | β | 2009 | β |
| Facilitatory actions of serotonin type 3 receptors on GABAergic inhibitory synaptic transmission in the spinal superficial dorsal horn. | Fukushima T et al. | β | 2009 | β |
| Fenfluramine disrupts the mitral valve interstitial cell response to serotonin. | Connolly JM et al. | β | 2009 | β |
| Functional characterization of contractions to tegaserod in human isolated proximal and distal coronary arteries. | Chan KY et al. | β | 2009 | β |
| Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder. | Szewczyk B et al. | β | 2009 | β |
| Guinea pig hippocampal 5-HT(1E) receptors: a tool for selective drug development. | Klein MT et al. | β | 2009 | β |
| Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists". | Toohey N et al. | β | 2009 | β |
| Hyperserotonemia in autism: activity of 5HT-associated platelet proteins. | HraniloviΔ D et al. | β | 2009 | β |
| Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. | Lee YS et al. | β | 2009 | β |
| Identification of novel serotonin 2C receptor ligands by sequential virtual screening. | Ahmed A et al. | β | 2009 | β |
| Immunohistochemical location of serotonin and serotonin 2B receptor in the small intestine of pigs. | Zhang H et al. | β | 2009 | β |
| Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat. | Levallet G et al. | β | 2009 | β |
| Inhibition of cardiac baroreflex by noxious thermal stimuli: a key role for lateral paragigantocellular serotonergic cells. | Gau R et al. | β | 2009 | β |
| Inhibition of the bradycardic component of the von Bezold-Jarisch reflex and carotid chemoreceptor reflex by periaqueductal gray stimulation: involvement of medullary receptors. | Netzer F et al. | β | 2009 | β |
| In vitro safety pharmacology profiling: what else beyond hERG? | Hamon J et al. | β | 2009 | β |
| Involvement of local serotonin-2A but not serotonin-1B receptors in the reinforcing effects of ethanol within the posterior ventral tegmental area of female Wistar rats. | Ding ZM et al. | β | 2009 | β |
| Local administration of sarizotan into the subthalamic nucleus attenuates levodopa-induced dyskinesias in 6-OHDA-lesioned rats. | Marin C et al. | β | 2009 | β |
| Long-term treatment with fluoxetine induces desensitization of 5-HT4 receptor-dependent signalling and functionality in rat brain. | Vidal R et al. | β | 2009 | β |
| Molecular epidemiology of major depressive disorder. | Kiyohara C et al. | β | 2009 | β |
| Motoneuron excitability: the importance of neuromodulatory inputs. | Heckman CJ et al. | β | 2009 | β |
| Neuropharmacology of performance monitoring. | Jocham G et al. | β | 2009 | β |
| NFAT1 transcription factor regulates pulmonary allergic inflammation and airway responsiveness. | Fonseca BP et al. | β | 2009 | β |
| [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy. | Maier DL et al. | β | 2009 | β |
| Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system. | Filip M et al. | β | 2009 | β |
| Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists. | Knight JA et al. | β | 2009 | β |
| Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium. | Gergs U et al. | β | 2009 | β |
| Quinazolindione derivatives as potent 5-HT3A receptor antagonists. | Lee BH et al. | β | 2009 | β |
| Role of dorsal raphe nucleus 5-HT(1A) and 5-HT(2) receptors in tonic immobility modulation in guinea pigs. | Ferreira MD et al. | β | 2009 | β |
| Rotarod impairment: catalepsy-like screening test for antipsychotic side effects. | Kirschbaum KM et al. | β | 2009 | β |
| Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse. | Da Silva Costa V et al. | β | 2009 | β |
| Serotonergic drugs and valvular heart disease. | Rothman RB et al. | β | 2009 | β |
| Serotonin 5-HT2B receptor in cardiac fibroblast contributes to cardiac hypertrophy: a new therapeutic target for heart failure? | Shyu KG | β | 2009 | β |
| Serotonin enhances platelet procoagulant properties and their activation induced during platelet tissue factor uptake. | Lopez-Vilchez I et al. | β | 2009 | β |
| Serotoninergic modulation of cortical and respiratory responses to episodic hypoxia. | Budzinska K | β | 2009 | β |
| Serotonin in affective control. | Dayan P et al. | β | 2009 | β |
| Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model. | MuΓ±oz A et al. | β | 2009 | β |
| Serotonin shapes risky decision making in monkeys. | Long AB et al. | β | 2009 | β |
| Serotonin targets inhibitory synapses to induce modulation of network functions. | Manzke T et al. | β | 2009 | β |
| Serotonylation of vascular proteins important to contraction. | Watts SW et al. | β | 2009 | β |
| Sex differences in NMDA receptor expression in human alcoholics. | Ridge JP et al. | β | 2009 | β |
| Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents. | Dosa PI et al. | β | 2009 | β |
| Solvent effects on the conformational preferences of serotonin: serotonin-(H(2)O)(n), n = 1,2. | LeGreve TA et al. | β | 2009 | β |
| Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function. | Fantini J et al. | β | 2009 | β |
| Structural basis of activation of cys-loop receptors: the extracellular-transmembrane interface as a coupling region. | Bartos M et al. | β | 2009 | β |
| Synthesis and pharmacological evaluation of new arylpiperazines N-[4-[4-(aryl) piperazine-1-yl]-phenyl]-amine derivatives: putative role of 5-HT1A receptors. | Khatri M et al. | β | 2009 | β |
| Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity. | Medina RA et al. | β | 2009 | β |
| The 5-HT7 receptor is involved in allocentric spatial memory information processing. | Sarkisyan G et al. | β | 2009 | β |
| The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction? | Paila YD et al. | β | 2009 | β |
| The love of a lifetime: 5-HT in the cardiovascular system. | Watts SW | β | 2009 | β |
| The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats. | Nakajima K et al. | β | 2009 | β |
| The response of neurons in the bed nucleus of the stria terminalis to serotonin: implications for anxiety. | Hammack SE et al. | β | 2009 | β |
| Trace amine-associated receptor 1 as a monoaminergic modulator in brain. | Xie Z et al. | β | 2009 | β |
| Treatment with ketanserin produces opioid-mediated hypoalgesia in the late phase of carrageenan-induced inflammatory hyperalgesia in rats. | Huang J et al. | β | 2009 | β |
| [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain. | Pierson ME et al. | β | 2008 | β |
| 2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists. | Shireman BT et al. | β | 2008 | β |
| 5-HT4 receptor agonists: similar but not the same. | De Maeyer JH et al. | β | 2008 | β |
| 5-HT(7) receptors in the modulation of cognitive processes. | Cifariello A et al. | β | 2008 | β |
| 5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. | Diaz J et al. | β | 2008 | β |
| Activation of septal 5-HT1A receptors alters spatial memory encoding, interferes with consolidation, but does not affect retrieval in rats subjected to a water-maze task. | Koenig J et al. | β | 2008 | β |
| Acute restriction impairs memory in the elevated T-maze (ETM) and modifies serotonergic activity in the dorsolateral striatum. | Cruz-Morales SE et al. | β | 2008 | β |
| A dual role of 5-hydroxytryptamine receptor 3 in serotonin induced ion transport in rat distal colon. | Yang N et al. | β | 2008 | β |
| Airway smooth muscle relaxation induced by 5-HT(2A) receptors: role of Na(+)/K(+)-ATPase pump and Ca(2+)-activated K(+) channels. | Campos-Bedolla P et al. | β | 2008 | β |
| Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection. | Lieberman JA et al. | β | 2008 | β |
| Blockade of 5-HT 1B receptors facilitates contextual aversive learning in mice by disinhibition of cholinergic and glutamatergic neurotransmission. | Eriksson TM et al. | β | 2008 | β |
| Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling. | Krzywkowski K et al. | β | 2008 | β |
| Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures. | SjΓΆgren B et al. | β | 2008 | β |
| Chronic buspirone treatment normalizes open field behavior in olfactory bulbectomized rats: assessment with a quantitative autoradiographic evaluation of the 5-HT1A binding sites. | Sato H et al. | β | 2008 | β |
| Cognitive dysfunction in neuropsychiatric disorders: selected serotonin receptor subtypes as therapeutic targets. | Terry AV et al. | β | 2008 | β |
| Conservation of structure, signaling and pharmacology between two serotonin receptor subtypes from decapod crustaceans, Panulirus interruptus and Procambarus clarkii. | Spitzer N et al. | β | 2008 | β |
| Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405). | Hirst WD et al. | β | 2008 | β |
| Critical role of B3 serotonergic cells in baroreflex inhibition during the defense reaction triggered by dorsal periaqueductal gray stimulation. | Bernard JF et al. | β | 2008 | β |
| Dendritic colocalisation of serotonin1B receptors and the glutamate NMDA receptor subunit NR1 within the hippocampal dentate gyrus: an ultrastructural study. | Peddie CJ et al. | β | 2008 | β |
| Developmental changes of serotonin 4(a) receptor expression in the rat pre-BΓΆtzinger complex. | Manzke T et al. | β | 2008 | β |
| Diphenyl diselenide exerts anxiolytic-like effect in Wistar rats: putative roles of GABAA and 5HT receptors. | Ghisleni G et al. | β | 2008 | β |
| Downregulated hypothalamic 5-HT3 receptor expression and enhanced 5-HT3 receptor antagonist-mediated improvement in fatigue-like behaviour in cholestatic rats. | Nguyen H et al. | β | 2008 | β |
| Dual dopamine/serotonin releasers: potential treatment agents for stimulant addiction. | Rothman RB et al. | β | 2008 | β |
| Effect of 5-HT(7) antagonist SB-269970 in the modulation of working and reference memory in the rat. | Gasbarri A et al. | β | 2008 | β |
| Excitatory and inhibitory 5-hydroxytryptamine (5-HT) receptors expressed in the isolated porcine uterine muscles. | Nakamura T et al. | β | 2008 | β |
| Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia. | Perez-GarcΓa G et al. | β | 2008 | β |
| Gender differences in brain activity evoked by muscle and cutaneous pain: a retrospective study of single-trial fMRI data. | Henderson LA et al. | β | 2008 | β |
| Genetic evaluation of the serotonergic system in chronic fatigue syndrome. | Smith AK et al. | β | 2008 | β |
| Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. | Holmes A | β | 2008 | β |
| Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis. | Kling A et al. | β | 2008 | β |
| High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor. | Krzywkowski K et al. | β | 2008 | β |
| How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective. | Clapp P et al. | β | 2008 | β |
| Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. | Xi ZX et al. | β | 2008 | β |
| Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. | Carola V et al. | β | 2008 | β |
| Increased social interaction in mice deficient of the striatal medium spiny neuron-specific phosphodiesterase 10A2. | Sano H et al. | β | 2008 | β |
| In vivo evidence for serotonin 5-HT2C receptor-mediated long-lasting excitability of lumbar spinal reflex and its functional interaction with 5-HT1A receptor in the mammalian spinal cord. | Gajendiran M | β | 2008 | β |
| Involvement of the serotonin system in L-dopa-induced dyskinesias. | Carta M et al. | β | 2008 | β |
| Locomotor stimulation produced by 3,4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain. | Baumann MH et al. | β | 2008 | β |
| Lysergic acid amide-induced posterior reversible encephalopathy syndrome with status epilepticus. | Legriel S et al. | β | 2008 | β |
| Maternal serotonin influences cardiac function in adult offspring. | Fligny C et al. | β | 2008 | β |
| Memory formation, amnesia, improved memory and reversed amnesia: 5-HT role. | Perez-Garcia G et al. | β | 2008 | β |
| Modulation of cholinergic functions by serotonin and possible implications in memory: general data and focus on 5-HT(1A) receptors of the medial septum. | Jeltsch-David H et al. | β | 2008 | β |
| Molecular biology of 5-HT receptors. | Hannon J et al. | β | 2008 | β |
| Molecular imaging of the 5-HT(1A) receptor in relation to human cognition. | Borg J | β | 2008 | β |
| Monoamine transporters and psychostimulant addiction. | Howell LL et al. | β | 2008 | β |
| New serotonin 5-HT(6) ligands from common feature pharmacophore hypotheses. | Kim HJ et al. | β | 2008 | β |
| Ontogeny of serotonin and serotonin2A receptors in rat auditory cortex. | Basura GJ et al. | β | 2008 | β |
| Opposing actions of 5HT1A and 5HT2-like serotonin receptors on modulations of the electric signal waveform in the electric fish Brachyhypopomus pinnicaudatus. | Allee SJ et al. | β | 2008 | β |
| Opposing roles for 5-HT2A and 5-HT2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time task. | Robinson ES et al. | β | 2008 | β |
| Pharmacology of 5HT(2C) receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editing. | Werry TD et al. | β | 2008 | β |
| Physiological endpoints for potential SSRI interactions in fish. | Kreke N et al. | β | 2008 | β |
| Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. | Fasching PA et al. | β | 2008 | β |
| Preparation of piperazine derivatives as 5-HT7 receptor antagonists. | Yoon J et al. | β | 2008 | β |
| Regional differences in 5-HT receptors in cerebral and testicular arterioles of the rat as revealed by Ca2+ imaging of real-time confocal microscopy: variances by artery size and organ specificity. | Masu K et al. | β | 2008 | β |
| RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function. | Werry TD et al. | β | 2008 | β |
| Selective serotonin reuptake inhibitors: a review of its effects on intraocular pressure. | Costagliola C et al. | β | 2008 | β |
| Serotonergic mechanisms in addiction-related memories. | Nic Dhonnchadha BA et al. | β | 2008 | β |
| Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT(2A/2C) receptors to modulate the post-ictal antinociception. | Freitas RL et al. | β | 2008 | β |
| Serotonin 1B receptor modulates frequency response curves and spectral integration in the inferior colliculus by reducing GABAergic inhibition. | Hurley LM et al. | β | 2008 | β |
| Serotonin evokes endocannabinoid release and retrogradely suppresses excitatory synapses. | Best AR et al. | β | 2008 | β |
| Serotonin pharmacology in the gastrointestinal tract: a review. | Beattie DT et al. | β | 2008 | β |
| Serotonin receptors. | Nichols DE et al. | β | 2008 | β |
| Serotonin receptors contribute to the promnesic effects of P. olacoides (Marapuama). | da Silva AL et al. | β | 2008 | β |
| Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts. | Nocito A et al. | β | 2008 | β |
| Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from in vitro and animal-based studies. | Warden SJ et al. | β | 2008 | β |
| Stimulation of contractions in human myometrium by serotonin is unmasked by smooth muscle relaxants. | Cordeaux Y et al. | β | 2008 | β |
| Stimulation of serotonin2C receptors influences cocaine-seeking behavior in response to drug-associated stimuli in rats. | Burbassi S et al. | β | 2008 | β |
| Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III. | Leopoldo M et al. | β | 2008 | β |
| Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors. | Blaazer AR et al. | β | 2008 | β |
| Synthesis and in-vitro pharmacological evaluation of new 5-HT1A receptor ligands containing a benzotriazinone nucleus. | Fiorino F et al. | β | 2008 | β |
| Synthesis and receptor binding of new thieno[2,3-d]-pyrimidines as selective ligands of 5-HT(3) receptors. | Modica MN et al. | β | 2008 | β |
| The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors. | Wang R et al. | β | 2008 | β |
| The development of tolerance to drugs that suppress food intake. | Fernstrom JD et al. | β | 2008 | β |
| The effects of the 5-HT(6) receptor agonist EMD and the 5-HT(7) receptor agonist AS19 on memory formation. | Meneses A et al. | β | 2008 | β |
| The goldfish (Carassius auratus) as a model for neuroendocrine signaling. | Popesku JT et al. | β | 2008 | β |
| The prevalence and etiology of nongenetic obesity and associated disorders. | Redinger RN | β | 2008 | β |
| Therapeutic potential of fluoxetine in neurological disorders. | Mostert JP et al. | β | 2008 | β |
| The role of 5-HT(1A) receptors in learning and memory. | Ogren SO et al. | β | 2008 | β |
| The selective serotonin reuptake inhibitor sertraline enhances counterregulatory responses to hypoglycemia. | Sanders NM et al. | β | 2008 | β |
| The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation. | Collet C et al. | β | 2008 | β |
| The skin as a mirror of the soul: exploring the possible roles of serotonin. | Nordlind K et al. | β | 2008 | β |
| Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system. | Chen HI et al. | β | 2008 | β |
| 5-HT1A-iCre, a new transgenic mouse line for genetic analyses of the serotonergic pathway. | Sahly I et al. | β | 2007 | β |
| 5-HT(1A) receptors and memory. | Meneses A et al. | β | 2007 | β |
| 5-HT2A serotoninergic receptor in the locus coeruleus participates in the first phase of lipopolysaccharide-induced fever. | da Silva AO et al. | β | 2007 | β |
| A comparison of the pharmacological properties of guinea-pig and human recombinant 5-HT4 receptors. | Vickery RG et al. | β | 2007 | β |
| Activation of the serotonin 1A receptor alters the temporal characteristics of auditory responses in the inferior colliculus. | Hurley LM | β | 2007 | β |
| Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. | de Foubert G et al. | β | 2007 | β |
| AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist. | Sharif NA et al. | β | 2007 | β |
| A pharmacological analysis of mice with a targeted disruption of the serotonin transporter. | Fox MA et al. | β | 2007 | β |
| Behavioral response to emotional stress in rabbits: role of serotonin and serotonin2A receptors. | Aloyo VJ et al. | β | 2007 | β |
| Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: synthesis and binding affinities for 5-HT(7) and 5-HT(1A) receptors. | Leopoldo M et al. | β | 2007 | β |
| Cardiovascular responses produced by 5-hydroxytriptamine:a pharmacological update on the receptors/mechanisms involved and therapeutic implications. | VillalΓ³n CM et al. | β | 2007 | β |
| Changes in the serotonergic system in the main olfactory bulb of rats unilaterally deprived from birth to adulthood. | GΓ³mez C et al. | β | 2007 | β |
| Characterization of the novel human serotonin receptor subunits 5-HT3C,5-HT3D, and 5-HT3E. | Niesler B et al. | β | 2007 | β |
| Comparison of the maturation of the adrenergic and serotonergic neurotransmitter systems in the brain: implications for differential drug effects on juveniles and adults. | Murrin LC et al. | β | 2007 | β |
| Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. | Neckameyer WS et al. | β | 2007 | β |
| Do serotonin(1-7) receptors modulate short and long-term memory? | Meneses A | β | 2007 | β |
| Effects of 5-hydroxytryptamine and substance P on neurons of the inferior salivatory nucleus. | Suwabe T et al. | β | 2007 | β |
| From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission. | Fuxe K et al. | β | 2007 | β |
| Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors. | Nyandege A et al. | β | 2007 | β |
| Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation. | Kalgutkar AS et al. | β | 2007 | β |
| Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important? | Coupar IM et al. | β | 2007 | β |
| Impact of nutrition on canine behaviour: current status and possible mechanisms. | Bosch G et al. | β | 2007 | β |
| Long-term serotonin effects in the rat are prevented by terguride. | Hauso Γ et al. | β | 2007 | β |
| Membrane organization and function of the serotonin(1A) receptor. | Kalipatnapu S et al. | β | 2007 | β |
| Memory consolidation and amnesia modify 5-HT6 receptors expression in rat brain: an autoradiographic study. | Meneses A et al. | β | 2007 | β |
| Mice deficient in the alpha subunit of G(z) show changes in pre-pulse inhibition, anxiety and responses to 5-HT(1A) receptor stimulation, which are strongly dependent on the genetic background. | van den Buuse M et al. | β | 2007 | β |
| Modified receptor internalization upon coexpression of 5-HT1B receptor and 5-HT2B receptors. | Janoshazi A et al. | β | 2007 | β |
| Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor. | Chang WC et al. | β | 2007 | β |
| Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression. | Krzywkowski K et al. | β | 2007 | β |
| Occipital cortical proton MRS at 4 Tesla in human moderate MDMA polydrug users. | Cowan RL et al. | β | 2007 | β |
| PET tracers for 5-HT(1A) receptors and uses thereof. | Kumar JS et al. | β | 2007 | β |
| Pharmacological characterization of 5-Hydroxytryptamine-receptor subtypes in circular muscle from the rat stomach. | Komada T et al. | β | 2007 | β |
| Pharmacology of serotonin-induced salivary secretion in Periplaneta americana. | Troppmann B et al. | β | 2007 | β |
| Role of the serotoninergic system in the sodium appetite control. | Reis LC | β | 2007 | β |
| Serotonin 5-HT(2C) receptor homodimerization is not regulated by agonist or inverse agonist treatment. | Herrick-Davis K et al. | β | 2007 | β |
| Serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine. | Thor KB et al. | β | 2007 | β |
| Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors. | MΓΌller CP et al. | β | 2007 | β |
| Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens. | Clotfelter ED et al. | β | 2007 | β |
| Serotonin-induced ion channel modulations in mesenteric artery myocytes from normotensive and DOCA-salt hypertensive rats. | Bae YM et al. | β | 2007 | β |
| Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. | Hampson LJ et al. | β | 2007 | β |
| Stimulation of growth hormone release by 5-hydroxytryptamine (5-HT) in cultured rat anterior pituitary cell aggregates: evidence for mediation by 5-HT2B, 5-HT7, 5-HT1B, and ketanserin-sensitive receptors. | Papageorgiou A et al. | β | 2007 | β |
| Synaptic transmission at functionally identified synapses in the enteric nervous system: roles for both ionotropic and metabotropic receptors. | Gwynne RM et al. | β | 2007 | β |
| Synthesis of a new scaffold: the 7H,8H-pyrimido[1,6-b]pyridazin-6,8-dione nucleus. | Herold F et al. | β | 2007 | β |
| The effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) on food intake in non-deprived C57BL6 mice. | Ebenezer IS et al. | β | 2007 | β |
| Thyroid status affects 5-HT2A receptor modulation of breathing before, during, and following exposure of hamsters to acute intermittent hypoxia. | Varney AA et al. | β | 2007 | β |
| Visual hallucinations in Parkinson's disease are not influenced by polymorphisms of serotonin 5-HT2A receptor and transporter genes. | Kiferle L et al. | β | 2007 | β |