Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex.
paper
Cited
Public
Unavailable
- Authors
- Rogers, R D; Owen, A M; Middleton, H C; Williams, E J; Pickard, J D; Sahakian, B J; Robbins, T W
- Year
- 1999
- Journal
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- PMID
- 10516320
- DOI
- 10.1523/JNEUROSCI.19-20-09029.1999
- PMCID
- PMC6782753
Patients sustaining lesions of the orbital prefrontal cortex (PFC) exhibit marked impairments in the performance of laboratory-based gambling, or risk-taking, tasks, suggesting that this part of the human PFC contributes to decision-making cognition. However, to date, little is known about the particular regions of the orbital cortex that participate in this function. In the present study, eight healthy volunteers were scanned, using H(2)(15)0 PET technology, while performing a novel computerized risk-taking task. The task involved predicting which of two mutually exclusive outcomes would occur, but critically, the larger reward (and penalty) was associated with choice of the least likely outcome, whereas the smallest reward (and penalty) was associated with choice of the most likely outcome. Resolving these "conflicting" decisions was associated with three distinct foci of regional cerebral blood flow increase within the right inferior and orbital PFC: laterally, in the anterior part of the middle frontal gyrus [Brodmann area 10 (BA 10)], medially, in the orbital gyrus (BA 11), and posteriorly, in the anterior portion of the inferior frontal gyrus (BA 47). By contrast, increases in the degree of conflict inherent in these decisions was associated with only limited changes in activity within orbital PFC and the anterior cingulate cortex. These results suggest that decision making recruits neural activity from multiple regions of the inferior PFC that receive information from a diverse set of cortical and limbic inputs, and that the contribution of the orbitofrontal regions may involve processing changes in reward-related information.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. | 2010 | 20035952 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Neurobehavioural links from infant screen time to anxiety. | Huang P et al. | β | 2026 | β |
| Advances in discerning the mechanisms underlying depression and resiliency: relation to the neurobiology of stress and the effects of antidepressants. | Gold PW et al. | β | 2025 | β |
| Early Postnatal Infection With Human Cytomegalovirus Has Long-Term Consequences on Brain Structure of Former Preterm Born Children. | MΓΌller M et al. | β | 2025 | β |
| Local cortical structure pattern and genetic links in schizophrenia: An MRI and CRISPR/Cas9 study. | Hou PS et al. | β | 2025 | β |
| Role of cognitive estimation in decision making: evidence from patients with prefrontal cortex damage. | Ouerchefani R et al. | β | 2025 | β |
| A scoping review on self-regulation and reward processing measured with gambling tasks: Evidence from the general youth population. | Bentivegna F et al. | β | 2024 | β |
| Development of performance and learning rate evaluation models in robot-assisted surgery using electroencephalography and eye-tracking. | Shafiei SB et al. | β | 2024 | β |
| Examining the interaction between prenatal stress and polygenic risk for attention-deficit/hyperactivity disorder on brain growth in childhood: Findings from the DREAM BIG consortium. | LΓ³pez-Vicente M et al. | β | 2024 | β |
| Exploring decision-making performance in young adults with mental health disorders: a comparative study using the Cambridge gambling task. | Effah R et al. | β | 2024 | β |
| Global neural self-disturbance in schizophrenia: A systematic fMRI review. | Sabbah SG et al. | β | 2024 | β |
| Perturbations in risk/reward decision making and frontal cortical catecholamine regulation induced by mild traumatic brain injury. | Knapp CP et al. | β | 2024 | β |
| Social isolation postweaning alters reward-related dopamine dynamics in a region-specific manner in adolescent male rats. | Lallai V et al. | β | 2024 | β |
| The relationship between mental health and risky decision-making in children and adolescents: a scoping review. | Bentivegna F et al. | β | 2024 | β |
| A systematic review and meta-analysis of risky decision-making in specific domains of problematic use of the internet: Evidence across different decision-making tasks. | MΓΌller SM et al. | β | 2023 | β |
| Decision-making difficulties mediate the association between poor emotion regulation and eating disorder symptoms in adolescence. | Francesconi M et al. | β | 2023 | β |
| Decision-making under ambiguity and risk and executive functions in Parkinson's disease patients: A scoping review of the studies investigating the Iowa Gambling Task and the Game of Dice. | Colautti L et al. | β | 2023 | β |
| Emotion-related impulsivity and risky decision-making: A systematic review and meta-regression. | Elliott MV et al. | β | 2023 | β |
| Impulsive choice in individuals with comorbid amphetamine use disorder and attention deficit-hyperactivity disorder. | Brynte C et al. | β | 2023 | β |
| Internal Capsule/Nucleus Accumbens Deep Brain Stimulation Increases Impulsive Decision Making in Obsessive-Compulsive Disorder. | SchΓΌller T et al. | β | 2023 | β |
| Methylphenidate undermines or enhances divergent creativity depending on baseline dopamine synthesis capacity. | SayalΔ± C et al. | β | 2023 | β |
| Neural circuits underlying language control and modality control in bilinguals: An fMRI study. | Liu H et al. | β | 2023 | β |
| Reciprocal associations between affective decision-making and mental health in adolescence. | Bentivegna F et al. | β | 2023 | β |
| The Neurobase of ambiguity loss aversion about decision making. | Hu Y et al. | β | 2023 | β |
| The role of ventral tegmental area in chronic stroke rehabilitation: an exploratory study. | Astrakas LG et al. | β | 2023 | β |
| A Censored Mixture Model for Modeling Risk Taking. | Dijkstra NFS et al. | β | 2022 | β |
| Behavior of Rats in a Self-Paced Risky Decision-Making Task Based on Definite Probability. | Yang M et al. | β | 2022 | β |
| Cannabidiol effects on cognition in individuals with cocaine use disorder: Exploratory results from a randomized controlled trial. | Rizkallah E et al. | β | 2022 | β |
| Decision-making and risk-taking in forensic and non-forensic patients with schizophrenia spectrum disorders: A multicenter European study. | Iozzino L et al. | β | 2022 | β |
| Decision Making: a Theoretical Review. | Morelli M et al. | β | 2022 | β |
| Decision-Making in Childhood Predicts Prodromal Eating Pathology in Adolescence. | Harrison A et al. | β | 2022 | β |
| Driver's turning intent recognition model based on brain activation and contextual information. | Trende A et al. | β | 2022 | β |
| Effect of alcohol use disorder family history on cognitive function. | Khemiri L et al. | β | 2022 | β |
| Intranasal Oxytocin Modulates Decision-Making Depending on Outcome Predictability-A Randomized Within-Subject Controlled Trial in Healthy Males. | Zebhauser PT et al. | β | 2022 | β |
| Markers of elevated oxidative stress in oligodendrocytes captured from the brainstem and occipital cortex in major depressive disorder and suicide. | Chandley MJ et al. | β | 2022 | β |
| Mismatch negativity and P3a in drug-naive adults with attention-deficit hyperactivity disorder. | Hsieh MH et al. | β | 2022 | β |
| Multimodal Assessment of Schizophrenia and Depression Utilizing Video, Acoustic, Locomotor, Electroencephalographic, and Heart Rate Technology: Protocol for an Observational Study. | Cotes RO et al. | β | 2022 | β |
| Posterior fronto-medial atrophy reflects decreased loss aversion, but not executive impairment, in alcohol use disorder. | Gianelli C et al. | β | 2022 | β |
| Probabilistic Reinforcement Learning and Anhedonia. | Kangas BD et al. | β | 2022 | β |
| Role of dopamine and clinical heterogeneity in cognitive dysfunction in Parkinson's disease. | Cools R et al. | β | 2022 | β |
| Sex moderates the effects of total sleep deprivation and sleep restriction on risk preference. | Lim JYL et al. | β | 2022 | β |
| The Computational and Neural Substrates of Ambiguity Avoidance in Anxiety. | Lawrance EL et al. | β | 2022 | β |
| The Effects of a Single Transcranial Direct Current Stimulation Session on Impulsivity and Risk Among a Sample of Adult Recreational Cannabis Users. | Patel H et al. | β | 2022 | β |
| Theoretical conceptualization of online privacy-related decision makingβ-βIntroducing the tripartite self-disclosure decision model. | Ostendorf S et al. | β | 2022 | β |
| The role of primary school composition in affective decision-making: a prospective cohort study. | Papachristou E et al. | β | 2022 | β |
| Types of Eating Disorder Prodrome in Adolescence: The Role of Decision Making in Childhood. | Harrison A et al. | β | 2022 | β |
| A 4-year longitudinal neuroimaging study of cognitive control using latent growth modeling: developmental changes and brain-behavior associations. | Kim-Spoon J et al. | β | 2021 | β |
| Endocrine Factors in Key Structural and Intracellular Changes in Depression. | Gold PW | β | 2021 | β |
| Functional brain network reorganization in HIV infection. | Minosse S et al. | β | 2021 | β |
| Functional connectivity density alterations in middle-age retinal detachment patients. | Shao Y et al. | β | 2021 | β |
| Increased decision latency in alcohol use disorder reflects altered resting-state synchrony in the anterior salience network. | Canessa N et al. | β | 2021 | β |
| In vivo microdialysis shows differential effects of prenatal protein malnutrition and stress on norepinephrine, dopamine, and serotonin levels in rat orbital frontal cortex. | Church NT et al. | β | 2021 | β |
| Matched neurofeedback during fMRI differentially activates reward-related circuits in active and sham groups. | Guler S et al. | β | 2021 | β |
| Neuroanatomical Correlates of Impulsive Choices and Risky Decision Making in Young Chronic Tobacco Smokers: A Voxel-Based Morphometry Study. | Conti AA et al. | β | 2021 | β |
| Quantitative EEG in Childhood Attention Deficit Hyperactivity Disorder and Learning Disabilities. | Chiarenza GA | β | 2021 | β |
| Risky decision-making in suicide attempters, and the choice of a violent suicidal means: an updated meta-analysis. | Perrain R et al. | β | 2021 | β |
| The laminar pattern of resting state in human cerebral cortex. | Egbert AR et al. | β | 2021 | β |
| The miRNome of Depression. | Ε»urawek D et al. | β | 2021 | β |
| Are candidate neurocognitive endophenotypes of OCD present in paediatric patients? A systematic review. | Marzuki AA et al. | β | 2020 | β |
| Change in decision-making skills and risk for eating disorders in adolescence: A population-based study. | Francesconi M et al. | β | 2020 | β |
| Dissociable roles for the ventral and dorsal medial prefrontal cortex in cue-guided risk/reward decision making. | van Holstein M et al. | β | 2020 | β |
| Distinct Region- and Time-Dependent Functional Cortical Adaptations in C57BL/6J Mice after Short and Prolonged Alcohol Drinking. | Cannady R et al. | β | 2020 | β |
| Effects of Diazepam on Reaction Times to Stop and Go. | Sarkar S et al. | β | 2020 | β |
| Effects of frequent marijuana use on risky decision-making in young adult college students. | Casey JL et al. | β | 2020 | β |
| Effects ofΒ theΒ monoamine stabilizer (-)OSU6162 onΒ cognitive function inΒ alcohol dependence. | Khemiri L et al. | β | 2020 | β |
| Firearm ownership among young adults: Associations with impulsivity and impulse control disorders. | Grant JE et al. | β | 2020 | β |
| Impaired learning from regret and disappointment in alcohol use disorder. | Galandra C et al. | β | 2020 | β |
| Neural correlates of moral goodness and moral beauty judgments. | Cheng Q et al. | β | 2020 | β |
| Non-negative Matrix Factorization Reveals Resting-State Cortical Alpha Network Abnormalities in the First-Episode Schizophrenia Spectrum. | Phalen H et al. | β | 2020 | β |
| Obesity is associated with reduced orbitofrontal cortex volume: A coordinate-based meta-analysis. | Chen EY et al. | β | 2020 | β |
| Resting-State Functional MRI Study Demonstrates That the Density of Functional Connectivity Density Mapping Changes in Patients with Acute Eye Pain. | Zhou Z et al. | β | 2020 | β |
| Short-Term Fasting Selectively Influences Impulsivity in Healthy Individuals. | Howard M et al. | β | 2020 | β |
| sLORETA Source Localisation of Visual Mismatch Negativity in Dyslexic Children During Malay Orthographical Lexicon Stimulations. | Ali SA et al. | β | 2020 | β |
| The connections of the insular VEN area in great apes: A histologically-guided ex vivo diffusion tractography study. | Cabeen RP et al. | β | 2020 | β |
| The Effects of Non-invasive Brain Stimulation on Impulsivity in People with Mental Disorders: a Systematic Review and Explanatory Meta-Analysis. | Yang CC et al. | β | 2020 | β |
| Ventral Caudate and Anterior Insula Recruitment During Value Estimation of Passionate Rewarding Cues. | Duarte IC et al. | β | 2020 | β |
| Whom to Believe? Understanding and Modeling Brain Activity in Source Credibility Evaluation. | Kawiak A et al. | β | 2020 | β |
| An Investigation of Brain Functional Connectivity by Form of Craniosynostosis. | Sun AH et al. | β | 2019 | β |
| Brain dynamics during the sleep onset transition: An EEG source localization study. | Fernandez Guerrero A et al. | β | 2019 | β |
| Colouring perception: Package colour cues affect neural responses to sweet dairy drinks in reward and inhibition related regions. | Tijssen IOJM et al. | β | 2019 | β |
| Computing Value from Quality and Quantity in Human Decision-Making. | de Berker AO et al. | β | 2019 | β |
| Consumer Neuroscience and Digital/Social Media Health/Social Cause Advertisement Effectiveness. | Harris JM et al. | β | 2019 | β |
| Effects of healthy ageing on activation pattern within the brain during movement and motor imagery: an fMRI study | Budhdeo S et al. | β | 2019 | β |
| Effects of Positive and Negative Expectations on Human Pain Perception Engage Separate But Interrelated and Dependently Regulated Cerebral Mechanisms. | Shih YW et al. | β | 2019 | β |
| Endophenotypes of executive functions in obsessive compulsive disorder? A meta-analysis in unaffected relatives. | Zartaloudi E et al. | β | 2019 | β |
| European violence risk and mental disorders (EU-VIORMED): a multi-centre prospective cohort study protocol. | de Girolamo G et al. | β | 2019 | β |
| Event-related potentials in response to feedback following risk-taking in the hot version of the Columbia Card Task. | de Groot K et al. | β | 2019 | β |
| Functional Correlates of Resting-State Connectivity in the Default Mode Network of Heroin Users on Methadone Treatment and Medication-Free Therapeutic Community Program. | Kuo LW et al. | β | 2019 | β |
| Iowa Gambling Task Performance in Parkinson Disease Patients with Impulse Control Disorders. | Biars JW et al. | β | 2019 | β |
| Let's Open the Decision-Making Umbrella: A Framework for Conceptualizing and Assessing Features of Impaired Decision Making in Addiction. | Rochat L et al. | β | 2019 | β |
| Multivariate pattern analysis of the neural correlates of smoking cue attentional bias. | Elton A et al. | β | 2019 | β |
| Neurocognitive Pathways in Attention-Deficit/Hyperactivity Disorder and White Matter Microstructure. | Bessette KL et al. | β | 2019 | β |
| Peer problems, bullying involvement, and affective decision-making in adolescence. | Flouri E et al. | β | 2019 | β |
| Psychopathy and Decision-Making: Antisocial Factor Associated With Risky Decision-Making in Offenders. | Yao X et al. | β | 2019 | β |
| Relationships between executive function, working memory, and decision-making on the Iowa Gambling Task: Evidence from ventromedial patients, dorsolateral patients, and normal subjects. | Ouerchefani R et al. | β | 2019 | β |
| Selective changes in moral judgment by noninvasive brain stimulation of the medial prefrontal cortex. | Riva P et al. | β | 2019 | β |
| The Association of Non-obscene Socially Inappropriate Behavior With Attention-Deficit/Hyperactivity Disorder Symptoms, Conduct Problems, and Risky Decision Making in a Large Sample of Adolescents. | Brandt V et al. | β | 2019 | β |
| The role of intelligence in decision-making in early adolescence. | Flouri E et al. | β | 2019 | β |
| Two days of calorie deprivation impairs high level cognitive processes, mood, and self-reported exertion during aerobic exercise: A randomized double-blind, placebo-controlled study. | Giles GE et al. | β | 2019 | β |
| Working Memory Training in Alcohol Use Disorder: A Randomized Controlled Trial. | Khemiri L et al. | β | 2019 | β |
| Brain metabolic correlates of fatigue in Parkinson's disease: a PET study. | Zhang L et al. | β | 2018 | β |
| Decision-Making in Multiple Sclerosis Patients: A Systematic Review. | Neuhaus M et al. | β | 2018 | β |
| Differences in the cognitive profile of depression between racial groups. | Grant JE et al. | β | 2018 | β |
| Differential Contributions of Nucleus Accumbens Subregions to Cue-Guided Risk/Reward Decision Making and Implementation of Conditional Rules. | Floresco SB et al. | β | 2018 | β |
| Disentangling Risk and Uncertainty: When Risk-Taking Measures Are Not About Risk. | De Groot K et al. | β | 2018 | β |
| Early adolescent outcomes of joint developmental trajectories of problem behavior and IQ in childhood. | Flouri E et al. | β | 2018 | β |
| Hyperbaric Oxygen Therapy Can Induce Neuroplasticity and Significant Clinical Improvement in Patients Suffering From Fibromyalgia With a History of Childhood Sexual Abuse-Randomized Controlled Trial. | Hadanny A et al. | β | 2018 | β |
| Individual differences in risk taking and endogeneous levels of testosterone, estradiol, and cortisol: A systematic literature search and three independent meta-analyses. | Kurath J et al. | β | 2018 | β |
| Junior temperament character inventory together with quantitative EEG discriminate children with attention deficit hyperactivity disorder combined subtype from children with attention deficit hyperactivity disorder combined subtype plus oppositional defiant disorder. | Chiarenza GA et al. | β | 2018 | β |
| Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load. | Ivan VE et al. | β | 2018 | β |
| Stimulating Self-Regulation: A Review of Non-invasive Brain Stimulation Studies of Goal-Directed Behavior. | Kelley NJ et al. | β | 2018 | β |
| The Effects of rTMS on Impulsivity in Normal Adults: a Systematic Review and Meta-Analysis. | Yang CC et al. | β | 2018 | β |
| The role of the orbitofrontal cortex in alcohol use, abuse, and dependence. | Moorman DE | β | 2018 | β |
| Transcranial Direct Current Stimulation (tDCS) paired with a decision-making task reduces risk-taking in a clinically impulsive sample. | Gilmore CS et al. | β | 2018 | β |
| Activation of the DLPFC Reveals an Asymmetric Effect in Risky Decision Making: Evidence from a tDCS Study. | Huang D et al. | β | 2017 | β |
| A diffusion spectrum imaging-based tractographic study into the anatomical subdivision and cortical connectivity of the ventral external capsule: uncinate and inferior fronto-occipital fascicles. | Panesar SS et al. | β | 2017 | β |
| Affective mapping: An activation likelihood estimation (ALE) meta-analysis. | Kirby LAJ et al. | β | 2017 | β |
| A neural network that links brain function, white-matter structure and risky behavior. | Kohno M et al. | β | 2017 | β |
| Case report: fainting during acupuncture stimulation at acupuncture point LI4. | Kwon OS et al. | β | 2017 | β |
| Challenges in accurately modeling the complexity of human ingestive behavior: the influence of portion size and energy density of food on fMRI food-cue reactivity. | Binks M et al. | β | 2017 | β |
| Challenges of implementing a personalized mental task near-infrared spectroscopy brain-computer interface for a non-verbal young adult with motor impairments. | Weyand S et al. | β | 2017 | β |
| Cognitive dysfunction in body dysmorphic disorder: new implications for nosological systems and neurobiological models. | Jefferies-Sewell K et al. | β | 2017 | β |
| Contribution of different regions of the prefrontal cortex and lesion laterality to deficit of decision-making on the Iowa Gambling Task. | Ouerchefani R et al. | β | 2017 | β |
| Discrepancy between social and nonsocial decision-making under uncertainty following prefrontal lobe damage: the impact of an interactionist approach. | Besnard J et al. | β | 2017 | β |
| Dissociating maternal responses to sad and happy facial expressions of their own child: An fMRI study. | Kluczniok D et al. | β | 2017 | β |
| Dissociation between decision-making under risk and decision-making under ambiguity in premanifest and manifest Huntington's disease. | Adjeroud N et al. | β | 2017 | β |
| Early Huntington's Disease: Impulse Control Deficits but Correct Judgment Regarding Risky Situations. | Galvez V et al. | β | 2017 | β |
| Gunslingers, poker players, and chickens 1: Decision making under physical performance pressure in elite athletes. | Parkin BL et al. | β | 2017 | β |
| Higher Trait Psychopathy Is Associated with Increased Risky Decision-Making and Less Coincident Insula and Striatal Activity. | Sutherland MT et al. | β | 2017 | β |
| Hot and Cool Executive Functions in Adolescence: Development and Contributions to Important Developmental Outcomes. | Poon K | β | 2017 | β |
| Lesions of the Orbitofrontal but Not Medial Prefrontal Cortex Affect Cognitive Judgment Bias in Rats. | Golebiowska J et al. | β | 2017 | β |
| Maternal depression and trajectories of child internalizing and externalizing problems: the roles of child decision making and working memory. | Flouri E et al. | β | 2017 | β |
| Maternal psychological distress and child decision-making. | Flouri E et al. | β | 2017 | β |
| Modulating the Activity of the DLPFC and OFC Has Distinct Effects on Risk and Ambiguity Decision-Making: A tDCS Study. | Yang X et al. | β | 2017 | β |
| Modulating the activity of the dorsolateral prefrontal cortex by tDCS alters distributive decisions behind the veil of ignorance via risk preference. | Luo J et al. | β | 2017 | β |
| Neuromodulation interventions for addictive disorders: challenges, promise, and roadmap for future research. | Spagnolo PA et al. | β | 2017 | β |
| Resting Brain Activity Related to Dispositional Mindfulness: a PET Study. | GartenschlΓ€ger M et al. | β | 2017 | β |
| Resting-State Functional Connectivity Within Medial Prefrontal Cortex Mediates Age Differences in Risk Taking. | Yu J et al. | β | 2017 | β |
| Social risky decision-making reveals gender differences in the TPJ: A hyperscanning study using functional near-infrared spectroscopy. | Zhang M et al. | β | 2017 | β |
| Sub-clinical Alcohol Consumption and Gambling Disorder. | Harries MD et al. | β | 2017 | β |
| The cerebellum in drug craving. | Moreno-Rius J et al. | β | 2017 | β |
| The relationship of approach/avoidance motivation and asymmetric frontal cortical activity: A review of studies manipulating frontal asymmetry. | Kelley NJ et al. | β | 2017 | β |
| Activation of the prefrontal cortex by unilateral transcranial direct current stimulation leads to an asymmetrical effect on risk preference in frames of gain and loss. | Ye H et al. | β | 2016 | β |
| Anatomic Connections of the Subgenual Cingulate Region. | Vergani F et al. | β | 2016 | β |
| Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization. | Alshuft HM et al. | β | 2016 | β |
| Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol. | Nimitvilai S et al. | β | 2016 | β |
| Cytoarchitecture and probability maps of the human medial orbitofrontal cortex. | Henssen A et al. | β | 2016 | β |
| Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. | Murray DE et al. | β | 2016 | β |
| Functional alterations of fronto-limbic circuit and default mode network systems in first-episode, drug-naΓ―ve patients with major depressive disorder: A meta-analysis of resting-state fMRI data. | Zhong X et al. | β | 2016 | β |
| Impact of childhood emotional abuse on neocortical neurometabolites and complex emotional processing in patients with generalized anxiety disorder. | Raparia E et al. | β | 2016 | β |
| Multifaceted Contributions by Different Regions of the Orbitofrontal and Medial Prefrontal Cortex to Probabilistic Reversal Learning. | Dalton GL et al. | β | 2016 | β |
| Prefrontal mechanisms of comorbidity from a transdiagnostic and ontogenic perspective. | Macdonald AN et al. | β | 2016 | β |
| Racial-ethnic related clinical and neurocognitive differences in adults with gambling disorder. | Chamberlain SR et al. | β | 2016 | β |
| Stress reactivity and personality in extreme sport athletes: The psychobiology of BASE jumpers. | Monasterio E et al. | β | 2016 | β |
| Understanding Risk-taking Behavior in Bullies, Victims, and Bully Victims Using Cognitive- and Emotion-Focused Approaches. | Poon K | β | 2016 | β |
| Action-outcome relationships are represented differently by medial prefrontal and orbitofrontal cortex neurons during action execution. | Simon NW et al. | β | 2015 | β |
| An fMRI Study of Risky Decision Making: The Role of Mental Preparation and Conflict. | Sohrabi A et al. | β | 2015 | β |
| Capturing neuroplastic changes after bimanual intensive rehabilitation in children with unilateral spastic cerebral palsy: A combined DTI, TMS and fMRI pilot study. | Bleyenheuft Y et al. | β | 2015 | β |
| Cocaine choice procedures in animals, humans, and treatment-seekers: Can we bridge the divide? | Moeller SJ et al. | β | 2015 | β |
| Decision Making Under Objective Risk Conditions-a Review of Cognitive and Emotional Correlates, Strategies, Feedback Processing, and External Influences. | Schiebener J et al. | β | 2015 | β |
| Divergence and Convergence of Risky Decision Making Across Prospective Gains and Losses: Preferences and Strategies. | Kurnianingsih YA et al. | β | 2015 | β |
| Does reward unpredictability reflect risk? | Anselme P | β | 2015 | β |
| ERP Correlates of Verbal and Numerical Probabilities in Risky Choices: A Two-Stage Probability Processing View. | Li S et al. | β | 2015 | β |
| Heightened eating drive and visual food stimuli attenuate central nociceptive processing. | Wright H et al. | β | 2015 | β |
| Impact of ADHD symptoms on clinical and cognitive aspects of problem gambling. | Chamberlain SR et al. | β | 2015 | β |
| Impaired decision making under ambiguity but not under risk in individuals with pathological buying-behavioral and psychophysiological evidence. | Trotzke P et al. | β | 2015 | β |
| Impulsivity as a predictor of treatment outcome in substance use disorders: review and synthesis. | Loree AM et al. | β | 2015 | β |
| Inactivation of the prelimbic or infralimbic cortex impairs decision-making in the rat gambling task. | Zeeb FD et al. | β | 2015 | β |
| Loss Frequency Versus Long-Term Outcome in Preschoolers' Decision Making on a Child Variant of the Iowa Gambling Task. | Garon N et al. | β | 2015 | β |
| Modulating activity in the prefrontal cortex changes decision-making for risky gains and losses: a transcranial direct current stimulation study. | Ye H et al. | β | 2015 | β |
| Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models. | Orsini CA et al. | β | 2015 | β |
| Neurocognitive findings in compulsive sexual behavior: a preliminary study. | Derbyshire KL et al. | β | 2015 | β |
| Neurostimulation for cognitive rehabilitation in stroke (NeuroCog): study protocol for a randomized controlled trial. | Andrade SM et al. | β | 2015 | β |
| Reward processing in neurodegenerative disease. | Perry DC et al. | β | 2015 | β |
| Self-reported strategies in decisions under risk: role of feedback, reasoning abilities, executive functions, short-term-memory, and working memory. | Schiebener J et al. | β | 2015 | β |
| Sex differences in ADHD symptom severity. | Arnett AB et al. | β | 2015 | β |
| Source localization of event-related brain activity elicited by food and nonfood odors. | Iannilli E et al. | β | 2015 | β |
| Synergetic fMRI-EEG brain mapping in alpha-rhythm voluntary control mode. | Shtark MB et al. | β | 2015 | β |
| The grey matter correlates of impaired decision-making in multiple sclerosis. | Muhlert N et al. | β | 2015 | β |
| Transcranial direct current stimulation over prefrontal cortex diminishes degree of risk aversion. | Ye H et al. | β | 2015 | β |
| Alterations of regional homogeneity in pediatric bipolar depression: a resting-state fMRI study. | Gao W et al. | β | 2014 | β |
| Among three different executive functions, general executive control ability is a key predictor of decision making under objective risk. | Schiebener J et al. | β | 2014 | β |
| Brain electrical source imaging in manic and depressive episodes of bipolar disorder. | Painold A et al. | β | 2014 | β |
| But do you think I'm cool? Developmental differences in striatal recruitment during direct and reflected social self-evaluations. | Jankowski KF et al. | β | 2014 | β |
| Cognitive correlates of under-ambiguity and under-risk decision making in high-functioning patients with relapsing remitting multiple sclerosis. | Cogo MG et al. | β | 2014 | β |
| Contrasting losses and gains increases the predictability of behavior by frontal EEG asymmetry. | Telpaz A et al. | β | 2014 | β |
| Decision-making deficits in patients diagnosed with disordered gambling using the Cambridge Gambling task: the effects of substance use disorder comorbidity. | Zois E et al. | β | 2014 | β |
| Decreased connectivity of the default mode network in pathological gambling: a resting state functional MRI study. | Jung MH et al. | β | 2014 | β |
| Discounting preferences and response consistency as markers of functional ability in community-dwelling older adults. | Lindbergh CA et al. | β | 2014 | β |
| Effect of varenicline on aspects of inhibitory control in smokers. | Austin AJ et al. | β | 2014 | β |
| Emotion-based learning: insights from the Iowa Gambling Task. | Turnbull OH et al. | β | 2014 | β |
| fNIRS derived hemodynamic signals and electrodermal responses in a sequential risk-taking task. | Holper L et al. | β | 2014 | β |
| Functionally aberrant electrophysiological cortical connectivities in first episode medication-naive schizophrenics from three psychiatry centers. | Lehmann D et al. | β | 2014 | β |
| Hemodynamic and affective correlates assessed during performance on the Columbia card task (CCT). | Holper L et al. | β | 2014 | β |
| High and low stimulus-driven conflict engage segregated brain networks, not quantitatively different resources. | Chouiter L et al. | β | 2014 | β |
| Impaired decision-making under risk in individuals with alcohol dependence. | Brevers D et al. | β | 2014 | β |
| Impulsivity as a vulnerability factor for poor addiction treatment outcomes: a review of neurocognitive findings among individuals with substance use disorders. | Stevens L et al. | β | 2014 | β |
| Modulation of smoking and decision-making behaviors with transcranial direct current stimulation in tobacco smokers: a preliminary study. | Fecteau S et al. | β | 2014 | β |
| Neural reward and punishment sensitivity in cigarette smokers. | Potts GF et al. | β | 2014 | β |
| Patients with chronic pain lack somatic markers during decision-making. | Elvemo NA et al. | β | 2014 | β |
| Performing behavioral tasks in subjects with intracranial electrodes. | Johnson MA et al. | β | 2014 | β |
| Poor working memory and reduced blood pressure levels in concurrent users of khat and tobacco. | Nakajima M et al. | β | 2014 | β |
| Prefrontal transcranial direct current stimulation alters activation and connectivity in cortical and subcortical reward systems: a tDCS-fMRI study. | Weber MJ et al. | β | 2014 | β |
| Prospective Optimization. | Sejnowski TJ et al. | β | 2014 | β |
| Reactive and regulative temperament in patients with compulsive buying and non-clinical controls measured by self-report and performance-based tasks. | Voth EM et al. | β | 2014 | β |
| Reconceptualizing major depressive disorder as an infectious disease. | Canli T | β | 2014 | β |
| Sexually dimorphic functional connectivity in response to high vs. low energy-dense food cues in obese humans: an fMRI study. | Atalayer D et al. | β | 2014 | β |
| Stress and decision making: neural correlates of the interaction between stress, executive functions, and decision making under risk. | Gathmann B et al. | β | 2014 | β |
| The profile of executive function in OCD hoarders and hoarding disorder. | Morein-Zamir S et al. | β | 2014 | β |
| The relationship between reward and punishment processing and the 5-HT1A receptor as shown by PET. | Faulkner P et al. | β | 2014 | β |
| Assaying the effect of levodopa on the evaluation of risk in healthy humans. | Symmonds M et al. | β | 2013 | β |
| Cognitive impairment in Parkinson's disease: the dual syndrome hypothesis. | Kehagia AA et al. | β | 2013 | β |
| Iowa Gambling Task (IGT): twenty years after - gambling disorder and IGT. | Brevers D et al. | β | 2013 | β |
| Is there a recovery of decision-making function after frontal lobe damage? A study using alternative versions of the Iowa Gambling Task. | Xiao L et al. | β | 2013 | β |
| Neuropsychological Functions of ΞΌ- and Ξ΄-Opioid Systems. | Polunina AG et al. | β | 2013 | β |
| Risk-taking and decision-making in youth: relationships to addiction vulnerability. | Balogh KN et al. | β | 2013 | β |
| Serotonin 2A receptors contribute to the regulation of risk-averse decisions. | Macoveanu J et al. | β | 2013 | β |
| The impact of the genome-wide supported variant in the cyclin M2 gene on gray matter morphology in schizophrenia. | Ohi K et al. | β | 2013 | β |
| A computational knowledge-based model for emulating human performance in the Iowa Gambling Task. | Iglesias A et al. | β | 2012 | β |
| Cerebral blood flow and freezing of gait in Parkinson's disease. | Imamura K et al. | β | 2012 | β |
| Decision making under ambiguity but not under risk is related to problem gambling severity. | Brevers D et al. | β | 2012 | β |
| Decision making under stress: a selective review. | Starcke K et al. | β | 2012 | β |
| Effects of transcranial direct-current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) during a mixed-gambling risky decision-making task. | Minati L et al. | β | 2012 | β |
| Executive function and suicidal risk in women with Borderline Personality Disorder. | Legris J et al. | β | 2012 | β |
| fMRI evidence for strategic decision-making during resolution of pronoun reference. | McMillan CT et al. | β | 2012 | β |
| How chunks, long-term working memory and templates offer a cognitive explanation for neuroimaging data on expertise acquisition: a two-stage framework. | Guida A et al. | β | 2012 | β |
| Impaired decision making in adolescent suicide attempters. | Bridge JA et al. | β | 2012 | β |
| Inactivating anterior insular cortex reduces risk taking. | Ishii H et al. | β | 2012 | β |
| Multiple sclerosis decreases explicit counterfactual processing and risk taking in decision making. | Simioni S et al. | β | 2012 | β |
| Neuro-anatomical correlates of a number bisection bias: A neuropsychological voxel-based morphometry study. | Woodbridge R et al. | β | 2012 | β |
| Neurocognitive deficits associated with shoplifting in young adults. | Grant JE et al. | β | 2012 | β |
| Neuropsychopharmacology and neurogenetic aspects of executive functioning: should reward gene polymorphisms constitute a diagnostic tool to identify individuals at risk for impaired judgment? | Bowirrat A et al. | β | 2012 | β |
| Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. | Irimia A et al. | β | 2012 | β |
| Responding in a test of decision-making under risk is under moderate genetic control in the rat. | Ashenhurst JR et al. | β | 2012 | β |
| Right-hemispheric cortical contributions to language ability in healthy adults. | Van Ettinger-Veenstra H et al. | β | 2012 | β |
| Risky decision-making in borderline personality disorder. | Svaldi J et al. | β | 2012 | β |
| Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. | SamamΓ© C et al. | β | 2012 | β |
| The behavioral activation system and mania. | Johnson SL et al. | β | 2012 | β |
| The detrimental effects of emotional process dysregulation on decision-making in substance dependence. | Murphy A et al. | β | 2012 | β |
| The effect of intravenous alcohol on the neural correlates of risky decision making in healthy social drinkers. | Gilman JM et al. | β | 2012 | β |
| The functional neuroanatomy of decision-making. | Rosenbloom MH et al. | β | 2012 | β |
| The question shapes the answer: the neural correlates of task differences reveal dynamic semantic processing. | Hargreaves IS et al. | β | 2012 | β |
| Transcranial alternating current stimulation increases risk-taking behavior in the balloon analog risk task. | Sela T et al. | β | 2012 | β |
| Translational application of neuromodulation of decision-making. | Levasseur-Moreau J et al. | β | 2012 | β |
| When unconscious rewards boost cognitive task performance inefficiently: the role of consciousness in integrating value and attainability information. | Zedelius CM et al. | β | 2012 | β |
| White and gray matter abnormalities in narcolepsy with cataplexy. | Scherfler C et al. | β | 2012 | β |
| Age differences in risky choice: a meta-analysis. | Mata R et al. | β | 2011 | β |
| Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. | Shelton RC et al. | β | 2011 | β |
| An Overview of Psychological and Neurobiological Mechanisms by which Early Negative Experiences Increase Risk of Mood Disorders. | Hassel S et al. | β | 2011 | β |
| Are risky choices actually guided by a compensatory process? New insights from FMRI. | Rao LL et al. | β | 2011 | β |
| Contributions of subregions of the prefrontal cortex to the theory of mind and decision making. | Xi C et al. | β | 2011 | β |
| Decision Preceding Negativity in the Iowa Gambling Task: an ERP study. | Bianchin M et al. | β | 2011 | β |
| Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats. | Mitchell MR et al. | β | 2011 | β |
| Executive functions, categorization of probabilities, and learning from feedback: what does really matter for decision making under explicit risk conditions? | Schiebener J et al. | β | 2011 | β |
| Impulsivity and Parkinson's disease: more than just disinhibition. | Antonelli F et al. | β | 2011 | β |
| Lesions of the basolateral amygdala and orbitofrontal cortex differentially affect acquisition and performance of a rodent gambling task. | Zeeb FD et al. | β | 2011 | β |
| Mind the gap: bridging economic and naturalistic risk-taking with cognitive neuroscience. | Schonberg T et al. | β | 2011 | β |
| Neural substrates of decision making as measured with the Iowa Gambling Task in men with alexithymia. | Kano M et al. | β | 2011 | β |
| Neurobiology of decision-making in adolescents. | Shad MU et al. | β | 2011 | β |
| Parcellating the neuroanatomical basis of impaired decision-making in traumatic brain injury. | Newcombe VF et al. | β | 2011 | β |
| Pathological gambling in patients with Parkinson's disease is associated with fronto-striatal disconnection: a path modeling analysis. | Cilia R et al. | β | 2011 | β |
| The Balloon Analog Insurance Task (BAIT): a behavioral measure of protective risk management. | Essex BG et al. | β | 2011 | β |
| Uncovering putative neural markers of risk avoidance. | Roy AK et al. | β | 2011 | β |
| Alterations of decision making and underlying neural correlates after resection of a mediofrontal cortical dysplasia: A single case study. | Labudda K et al. | β | 2010 | β |
| Brain and autonomic association accompanying stochastic decision-making. | Ohira H et al. | β | 2010 | β |
| Cognitive and behavioural deficits associated with the orbitomedial prefrontal cortex in amyotrophic lateral sclerosis. | Meier SL et al. | β | 2010 | β |
| Decision-making cognition in neurodegenerative diseases. | Gleichgerrcht E et al. | β | 2010 | β |
| Decision-making impairments in women with binge eating disorder. | Svaldi J et al. | β | 2010 | β |
| Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. | Kamarajan C et al. | β | 2010 | β |
| Effort-based decision making in the rat: an [18F]fluorodeoxyglucose micro positron emission tomography study. | Endepols H et al. | β | 2010 | β |
| Impairment of fronto-striatal and parietal cerebral networks correlates with attention deficit hyperactivity disorder (ADHD) psychopathology in adults - a functional magnetic resonance imaging (fMRI) study. | Schneider MF et al. | β | 2010 | β |
| Increased ventral striatal BOLD activity during non-drug reward anticipation in cannabis users. | Nestor L et al. | β | 2010 | β |
| Khat use and neurobehavioral functions: suggestions for future studies. | Hoffman R et al. | β | 2010 | β |
| Modulation of decision-making in a gambling task in older adults with transcranial direct current stimulation. | Boggio PS et al. | β | 2010 | β |
| Neural substrates of alcohol-induced smoking urge in heavy drinking nondaily smokers. | King A et al. | β | 2010 | β |
| Neurobiological correlates of problem gambling in a quasi-realistic blackjack scenario as revealed by fMRI. | Miedl SF et al. | β | 2010 | β |
| Neuromodulation of decision-making in the addictive brain. | Fecteau S et al. | β | 2010 | β |
| No fear no risk! Human risk behavior is affected by chemosensory anxiety signals. | Haegler K et al. | β | 2010 | β |
| Prefrontal cortical contribution to risk-based decision making. | St Onge JR et al. | β | 2010 | β |
| Psychopathy and Risk Taking among Jailed Inmates. | Swogger MT et al. | β | 2010 | β |
| The International Society for Bipolar Disorders-Battery for Assessment of Neurocognition (ISBD-BANC). | Yatham LN et al. | β | 2010 | β |
| The reward circuit: linking primate anatomy and human imaging. | Haber SN et al. | β | 2010 | β |
| Why gamblers fail to win: a review of cognitive and neuroimaging findings in pathological gambling. | van Holst RJ et al. | β | 2010 | β |
| Bright and dark sides of impulsivity: performance of women with high and low trait impulsivity on neuropsychological tasks. | Perales JC et al. | β | 2009 | β |
| Decreased muscarinic receptor binding in the frontal cortex of bipolar disorder and major depressive disorder subjects. | Gibbons AS et al. | β | 2009 | β |
| Deficits in behavioral inhibition predict treatment engagement in prison inmates. | Fishbein D et al. | β | 2009 | β |
| Differential relationships between personal and community stressors and children's neurocognitive functioning. | Fishbein D et al. | β | 2009 | β |
| Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome. | Leeson VC et al. | β | 2009 | β |
| Economic games quantify diminished sense of guilt in patients with damage to the prefrontal cortex. | Krajbich I et al. | β | 2009 | β |
| Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. | Shelton RC et al. | β | 2009 | β |
| Getting mixed messages: the impact of conflicting social signals on the brain's target emotional response. | Amting JM et al. | β | 2009 | β |
| Individual differences in risk preference predict neural responses during financial decision-making. | Engelmann JB et al. | β | 2009 | β |
| Is depression associated with dysfunction of the central reward system? | Martin-Soelch C | β | 2009 | β |
| Is schizophrenia the price of human central nervous system complexity? | Dean B | β | 2009 | β |
| Its own reward: lessons to be drawn from the reversed-reward contingency paradigm. | Shifferman EM | β | 2009 | β |
| Lying about facial recognition: an fMRI study. | Bhatt S et al. | β | 2009 | β |
| Neural correlates of resolving uncertainty in driver's decision making. | Callan AM et al. | β | 2009 | β |
| Neural correlates of traditional Chinese medicine induced advantageous risk-taking decision making. | Lee TM et al. | β | 2009 | β |
| Neural correlates of value, risk, and risk aversion contributing to decision making under risk. | Christopoulos GI et al. | β | 2009 | β |
| Neural substrates of reward magnitude, probability, and risk during a wheel of fortune decision-making task. | Smith BW et al. | β | 2009 | β |
| Non-invasive brain stimulation in the detection of deception: scientific challenges and ethical consequences. | Luber B et al. | β | 2009 | β |
| On the differentiation of N2 components in an appetitive choice task: evidence for the revised Reinforcement Sensitivity Theory. | Leue A et al. | β | 2009 | β |
| Prefrontal brain morphology and executive function in healthy and depressed elderly. | Elderkin-Thompson V et al. | β | 2009 | β |
| Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder. | Kalmar JH et al. | β | 2009 | β |
| Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls. | Shelton RC et al. | β | 2009 | β |
| Regulation of natural killer cell redistribution by prefrontal cortex during stochastic learning. | Ohira H et al. | β | 2009 | β |
| Reward and social valuation deficits following ventromedial prefrontal damage. | Moretti L et al. | β | 2009 | β |
| Risk-prone individuals prefer the wrong options on a rat version of the Iowa Gambling Task. | Rivalan M et al. | β | 2009 | β |
| Selectivity of executive function deficits in mild cognitive impairment. | Brandt J et al. | β | 2009 | β |
| Sex-related differences in neural activity during risk taking: an fMRI study. | Lee TM et al. | β | 2009 | β |
| Single-cell and population coding of expected reward probability in the orbitofrontal cortex of the rat. | van Duuren E et al. | β | 2009 | β |
| The wick in the candle of learning: epistemic curiosity activates reward circuitry and enhances memory. | Kang MJ et al. | β | 2009 | β |
| A developmental study of risky decisions on the cake gambling task: age and gender analyses of probability estimation and reward evaluation. | Van Leijenhorst L et al. | β | 2008 | β |
| Age-related differences in neural activities during risk taking as revealed by functional MRI. | Lee TM et al. | β | 2008 | β |
| An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness. | Lee TM et al. | β | 2008 | β |
| A study investigating the acute dose-response effects of 13 mg and 17 mg Delta 9- tetrahydrocannabinol on cognitive-motor skills, subjective and autonomic measures in regular users of marijuana. | Weinstein A et al. | β | 2008 | β |
| Brain imaging in patients with freezing of gait. | Bartels AL et al. | β | 2008 | β |
| Brain imaging study of the acute effects of Delta9-tetrahydrocannabinol (THC) on attention and motor coordination in regular users of marijuana. | Weinstein A et al. | β | 2008 | β |
| Brain maps of Iowa gambling task. | Lin CH et al. | β | 2008 | β |
| Cannabis abuse is associated with decision-making impairment among first-episode patients with schizophrenia-spectrum psychosis. | Mata I et al. | β | 2008 | β |
| Decision-making impairments in the context of intact reward sensitivity in schizophrenia. | Heerey EA et al. | β | 2008 | β |
| Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making. | Clark L et al. | β | 2008 | β |
| Dissociating early and late error signals in perceptual recognition. | Wheeler ME et al. | β | 2008 | β |
| Distinguishing expected negative outcomes from preparatory control in the human orbitofrontal cortex. | Ursu S et al. | β | 2008 | β |
| Does the feedback from previous trials influence current decisions? A study on the role of feedback processing in making decisions under explicit risk conditions. | Brand M | β | 2008 | β |
| ERP correlates of complex human decision making in a gambling paradigm: detection and resolution of conflict. | Mennes M et al. | β | 2008 | β |
| Examining ventral and dorsal prefrontal function in bipolar disorder: a functional magnetic resonance imaging study. | Frangou S et al. | β | 2008 | β |
| Executive function deficits in short-term abstinent cannabis users. | McHale S et al. | β | 2008 | β |
| How Do Varied Populations Interact with Embodied Conversational Agents? Findings from Inner-city Adolescents and Prisoners. | Hubal RC et al. | β | 2008 | β |
| Impact of ambiguity and risk on decision making in mild Alzheimer's disease. | Sinz H et al. | β | 2008 | β |
| Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies. | Verdejo-GarcΓa A et al. | β | 2008 | β |
| Impulsivity is associated with behavioral decision-making deficits. | Franken IH et al. | β | 2008 | β |
| Inefficiency in self-organized attentional switching in the normal aging population is associated with decreased activity in the ventrolateral prefrontal cortex. | Hampshire A et al. | β | 2008 | β |
| Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task. | Strakowski SM et al. | β | 2008 | β |
| Making decisions and advising decisions in traumatic brain injury. | Bonatti E et al. | β | 2008 | β |
| Neural correlates of decision making with explicit information about probabilities and incentives in elderly healthy subjects. | Labudda K et al. | β | 2008 | β |
| Regional brain changes in bipolar I depression: a functional magnetic resonance imaging study. | Altshuler L et al. | β | 2008 | β |
| Relationship between lead exposure, cognitive function, and drug addiction: pilot study and research agenda. | Fishbein DH et al. | β | 2008 | β |
| Review. Parallel studies of cocaine-related neural and cognitive impairment in humans and monkeys. | Beveridge TJ et al. | β | 2008 | β |
| The innovative brain. | Lawrence A et al. | β | 2008 | β |
| The mediodorsal thalamic nucleus and schizophrenia. | AlelΓΊ-Paz R et al. | β | 2008 | β |
| The neural substrates of probabilistic and intertemporal decision making. | Weber BJ et al. | β | 2008 | β |
| The neuronal substrate of risky choice: an insight into the contributions of neuroimaging to the understanding of theories on decision making under risk. | Vorhold V | β | 2008 | β |
| Unconscious emotional reasoning and the therapeutic misconception. | Charuvastra A et al. | β | 2008 | β |
| Activation of prefrontal cortex by transcranial direct current stimulation reduces appetite for risk during ambiguous decision making. | Fecteau S et al. | β | 2007 | β |
| Adult Age Differences in Dual Information Processes: Implications for the Role of Affective and Deliberative Processes in Older Adults' Decision Making. | Peters E et al. | β | 2007 | β |
| A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania. | Chamberlain SR et al. | β | 2007 | β |
| Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. | Shaw P et al. | β | 2007 | β |
| Chronic auditory hallucinations in schizophrenic patients: MR analysis of the coincidence between functional and morphologic abnormalities. | MartΓ-BonmatΓ L et al. | β | 2007 | β |
| Decision-making with explicit and stable rules in mild Alzheimer's disease. | Delazer M et al. | β | 2007 | β |
| Differential effects of the D- and L- isomers of amphetamine on pharmacological MRI BOLD contrast in the rat. | Easton N et al. | β | 2007 | β |
| Diminishing risk-taking behavior by modulating activity in the prefrontal cortex: a direct current stimulation study. | Fecteau S et al. | β | 2007 | β |
| Dissociable but inter-related systems of cognitive control and reward during decision making: evidence from pupillometry and event-related fMRI. | Satterthwaite TD et al. | β | 2007 | β |
| Early cortical response to behaviorally relevant absence of anticipated outcomes: a human event-related potential study. | Schnider A et al. | β | 2007 | β |
| Evidence accumulation and the moment of recognition: dissociating perceptual recognition processes using fMRI. | Ploran EJ et al. | β | 2007 | β |
| From vice to virtue: insights from sensitization in the nonhuman primate. | Castner SA et al. | β | 2007 | β |
| Frontoparietal cortical activity of methamphetamine-dependent and comparison subjects performing a delay discounting task. | Monterosso JR et al. | β | 2007 | β |
| Gender differences in neurocognitive functioning among alcohol-dependent Russian patients. | Flannery B et al. | β | 2007 | β |
| Gray matter volume abnormalities and externalizing symptoms in subjects at high risk for alcohol dependence. | Benegal V et al. | β | 2007 | β |
| Measuring reward assessment in a semi-naturalistic context: the effects of selective amygdala, orbital frontal or hippocampal lesions. | Machado CJ et al. | β | 2007 | β |
| Neurocognitive and neuroimaging evidence of behavioural dysregulation in human drug addiction: implications for diagnosis, treatment and prevention. | YΓΌcel M et al. | β | 2007 | β |
| Neurocognitive characterizations of Russian heroin addicts without a significant history of other drug use. | Fishbein DH et al. | β | 2007 | β |
| Neuropsychological frontal impairments and negative symptoms in schizophrenia. | Martino DJ et al. | β | 2007 | β |
| Orbitofrontal cortex lesions disrupt risk assessment in a novel serial decision-making task for rats. | Pais-Vieira M et al. | β | 2007 | β |
| Prefrontal cortex activity is reduced in gambling and nongambling substance users during decision-making. | Tanabe J et al. | β | 2007 | β |
| Resisting the power of temptations: the right prefrontal cortex and self-control. | Knoch D et al. | β | 2007 | β |
| Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications. | Robbins TW | β | 2007 | β |
| Taste in the medial orbitofrontal cortex of the macaque. | Pritchard TC et al. | β | 2007 | β |
| The effects of low doses of delta-9 tetrahydrocannabinol on reinforcement processing in the risky decision-making of young healthy adults. | Rogers RD et al. | β | 2007 | β |
| The neural basis of risk ratings: evidence from a functional magnetic resonance imaging (fMRI) study. | Vorhold V et al. | β | 2007 | β |
| The neuropsychology of amphetamine and opiate dependence: implications for treatment. | Ersche KD et al. | β | 2007 | β |
| Anatomy of a decision: striato-orbitofrontal interactions in reinforcement learning, decision making, and reversal. | Frank MJ et al. | β | 2006 | β |
| A novel set-shifting modification of the iowa gambling task: flexible emotion-based learning in schizophrenia. | Turnbull OH et al. | β | 2006 | β |
| Brain mechanism of reward prediction under predictable and unpredictable environmental dynamics. | Tanaka SC et al. | β | 2006 | β |
| Cerebellar vermis involvement in cocaine-related behaviors. | Anderson CM et al. | β | 2006 | β |
| Differences in orbitofrontal activation during decision-making between methadone-maintained opiate users, heroin users and healthy volunteers. | Ersche KD et al. | β | 2006 | β |
| Disruption of right prefrontal cortex by low-frequency repetitive transcranial magnetic stimulation induces risk-taking behavior. | Knoch D et al. | β | 2006 | β |
| Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brain. | Yacubian J et al. | β | 2006 | β |
| Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making. | Krain AL et al. | β | 2006 | β |
| Dopaminergic modulation of cognitive function-implications for L-DOPA treatment in Parkinson's disease. | Cools R | β | 2006 | β |
| Error processing in major depressive disorder: evidence from event-related potentials. | Ruchsow M et al. | β | 2006 | β |
| Functions of frontostriatal systems in cognition: comparative neuropsychopharmacological studies in rats, monkeys and humans. | Chudasama Y et al. | β | 2006 | β |
| Impulsivity, reward sensitivity, and decision-making in subarachnoid hemorrhage survivors. | Salmond CH et al. | β | 2006 | β |
| Links between depression and substance abuse in adolescents: neurobiological mechanisms. | Rao U | β | 2006 | β |
| Mediators of the stress-substance-use relationship in urban male adolescents. | Fishbein DH et al. | β | 2006 | β |
| Neural systems implicated in delayed and probabilistic reinforcement. | Cardinal RN | β | 2006 | β |
| Neurobehavioural characteristics and relapse in addiction. | Bowden-Jones H et al. | β | 2006 | β |
| Neuropsychological correlates of decision-making in ambiguous and risky situations. | Brand M et al. | β | 2006 | β |
| On framing effects in decision making: linking lateral versus medial orbitofrontal cortex activation to choice outcome processing. | Windmann S et al. | β | 2006 | β |
| Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex. | Baird A et al. | β | 2006 | β |
| The neuropsychology of mood disorders. | Chamberlain SR et al. | β | 2006 | β |
| Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task. | Strakowski SM et al. | β | 2005 | β |
| Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. | Ersche KD et al. | β | 2005 | β |
| Acute effects of alprazolam on risky decision making in humans. | Lane SD et al. | β | 2005 | β |
| Acute marijuana effects on human risk taking. | Lane SD et al. | β | 2005 | β |
| Applying a cognitive neuroscience perspective to the disorder of psychopathy. | Blair RJ | β | 2005 | β |
| Assessment of hot and cool executive function in young children: age-related changes and individual differences. | Hongwanishkul D et al. | β | 2005 | β |
| Brain activations associated with probability matching. | Miller MB et al. | β | 2005 | β |
| Cognitive performance and autonomic reactivity in abstinent drug abusers and nonusers. | Fishbein D et al. | β | 2005 | β |
| Construct validity of the Balloon Analog Risk Task (BART): associations with psychopathy and impulsivity. | Hunt MK et al. | β | 2005 | β |
| Decision-making deficits of korsakoff patients in a new gambling task with explicit rules: associations with executive functions. | Brand M et al. | β | 2005 | β |
| Deficits in decision-making in head injury survivors. | Salmond CH et al. | β | 2005 | β |
| Effects of lesions of the nucleus accumbens core on choice between small certain rewards and large uncertain rewards in rats. | Cardinal RN et al. | β | 2005 | β |
| Functional activity related to risk anticipation during performance of the Iowa Gambling Task. | Fukui H et al. | β | 2005 | β |
| Imaging monetary reward in pathological gamblers. | Hollander E et al. | β | 2005 | β |
| Impaired "affective theory of mind" is associated with right ventromedial prefrontal damage. | Shamay-Tsoory SG et al. | β | 2005 | β |
| Impaired decision making in suicide attempters. | Jollant F et al. | β | 2005 | β |
| Integrating functional neuroimaging and human operant research: brain activation correlated with presentation of discriminative stimuli. | Schlund MW et al. | β | 2005 | β |
| MDMA affects both error-rate dependent and independent aspects of decision-making in a two-choice prediction task. | Vollenweider FX et al. | β | 2005 | β |
| Organization of frontohippocampal neuronal networks in cats in different types of directed behavior. | Merzhanova GKh et al. | β | 2005 | β |
| Prefrontal cognitive functions in stabilized first-episode patients with schizophrenia spectrum disorders: a dissociation between dorsolateral and orbitofrontal functioning. | RodrΓguez-SΓ‘nchez JM et al. | β | 2005 | β |
| Prefrontal serotonin depletion affects reversal learning but not attentional set shifting. | Clarke HF et al. | β | 2005 | β |
| Punishment induces risky decision-making in methadone-maintained opiate users but not in heroin users or healthy volunteers. | Ersche KD et al. | β | 2005 | β |
| Reward-based decision-making and aging. | Marschner A et al. | β | 2005 | β |
| Risk-taking on tests sensitive to ventromedial prefrontal cortex dysfunction predicts early relapse in alcohol dependency: a pilot study. | Bowden-Jones H et al. | β | 2005 | β |
| Risky decision making and the anterior cingulate cortex in abstinent drug abusers and nonusers. | Fishbein DH et al. | β | 2005 | β |
| Role of the orbitofrontal cortex in reinforcement processing and inhibitory control: evidence from functional magnetic resonance imaging studies in healthy human subjects. | Elliott R et al. | β | 2005 | β |
| Subjective awareness on the Iowa Gambling Task: the key role of emotional experience in schizophrenia. | Evans CE et al. | β | 2005 | β |
| Substance use disorders and the orbitofrontal cortex: systematic review of behavioural decision-making and neuroimaging studies. | Dom G et al. | β | 2005 | β |
| Sustained neural activity associated with cognitive control during temporally extended decision making. | Yarkoni T et al. | β | 2005 | β |
| The effect of social content on deductive reasoning: an fMRI study. | Canessa N et al. | β | 2005 | β |
| The effects of the quality and probability of reinforcement on feeder selection by lobectomized dogs. | Preobrazhenskaya LA et al. | β | 2005 | β |
| The human orbitofrontal cortex: linking reward to hedonic experience. | Kringelbach ML | β | 2005 | β |
| The human orbitofrontal cortex monitors outcomes even when no reward is at stake. | Schnider A et al. | β | 2005 | β |
| The man who turned bad. | Stein DJ et al. | β | 2005 | β |
| Three-dimensional stereotactic surface projection study of freezing of gait and brain perfusion image in Parkinson's disease. | Matsui H et al. | β | 2005 | β |
| Treatment of substance use disorders in schizophrenia: a unifying neurobiological mechanism? | Roth RM et al. | β | 2005 | β |
| Variants of uncertainty in decision-making and their neural correlates. | Volz KG et al. | β | 2005 | β |
| Addiction, a condition of compulsive behaviour? Neuroimaging and neuropsychological evidence of inhibitory dysregulation. | Lubman DI et al. | β | 2004 | β |
| Adolescents' performance on the Iowa Gambling Task: implications for the development of decision making and ventromedial prefrontal cortex. | Hooper CJ et al. | β | 2004 | β |
| A functional neuroimaging study of motivation and executive function. | Taylor SF et al. | β | 2004 | β |
| Anterior cingulate activation in high trait anxious subjects is related to altered error processing during decision making. | Paulus MP et al. | β | 2004 | β |
| Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. | Ramnani N et al. | β | 2004 | β |
| Brain activity during distention of the descending colon in humans. | Hamaguchi T et al. | β | 2004 | β |
| Chemistry of the adaptive mind. | Cools R et al. | β | 2004 | β |
| Choice selection and reward anticipation: an fMRI study. | Ernst M et al. | β | 2004 | β |
| Cognitive impairments in cerebellar degeneration: a comparison with Huntington's disease. | Brandt J et al. | β | 2004 | β |
| Context dependence of the event-related brain potential associated with reward and punishment. | Holroyd CB et al. | β | 2004 | β |
| Developmental changes in real life decision making: performance on a gambling task previously shown to depend on the ventromedial prefrontal cortex. | Crone EA et al. | β | 2004 | β |
| Development of orbitofrontal function: current themes and future directions. | Happaney K et al. | β | 2004 | β |
| Diazepam produces disinhibitory cognitive effects in male volunteers. | Deakin JB et al. | β | 2004 | β |
| Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism: II. Effects of reward preference. | Pessiglione M et al. | β | 2004 | β |
| Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. | Rogers RD et al. | β | 2004 | β |
| Effects of beta-adrenoceptor blockade on components of human decision-making. | Rogers RD et al. | β | 2004 | β |
| Emotional perseveration: an update on prefrontal-amygdala interactions in fear extinction. | Sotres-Bayon F et al. | β | 2004 | β |
| Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents. | May JC et al. | β | 2004 | β |
| Interneuronal frontohippocampal interactions in cats trained to choose on the basis of reinforcement quality. | Merzhanova GKh et al. | β | 2004 | β |
| Orbitofrontal cortex tracks positive mood in mothers viewing pictures of their newborn infants. | Nitschke JB et al. | β | 2004 | β |
| Patients with right frontal lesions are unable to assess and use advice to make predictive judgments. | Gomez-Beldarrain M et al. | β | 2004 | β |
| Performance on the IOWA card task by adolescents and adults. | Overman WH et al. | β | 2004 | β |
| Prediction error for free monetary reward in the human prefrontal cortex. | Ramnani N et al. | β | 2004 | β |
| Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops. | Tanaka SC et al. | β | 2004 | β |
| Reinforcement learning and decision making in monkeys during a competitive game. | Lee D et al. | β | 2004 | β |
| Reward-related processes in pediatric bipolar disorder: a pilot study. | Ernst M et al. | β | 2004 | β |
| Risk taking during decision-making in normal volunteers changes with age. | Deakin J et al. | β | 2004 | β |
| Selective activation of the nucleus accumbens during risk-taking decision making. | Matthews SC et al. | β | 2004 | β |
| Social and emotional decision-making following frontal lobe injury. | Clark L et al. | β | 2004 | β |
| The basal ganglia: anatomy, physiology, and pharmacology. | Tisch S et al. | β | 2004 | β |
| The cognitive neuroscience of human decision making: a review and conceptual framework. | Fellows LK | β | 2004 | β |
| The development of a trial making test in young children: the TRAILS-P. | Espy KA et al. | β | 2004 | β |
| The effects of tyrosine depletion in normal healthy volunteers: implications for unipolar depression. | McLean A et al. | β | 2004 | β |
| The neural basis of conditional reasoning with arbitrary content. | Noveck IA et al. | β | 2004 | β |
| The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning. | Clark L et al. | β | 2004 | β |
| Theory of mind, social development, and psychosis. | Casacchia M et al. | β | 2004 | β |
| The role of emotion in decision-making: evidence from neurological patients with orbitofrontal damage. | Bechara A | β | 2004 | β |
| Using developmental, cognitive, and neuroscience approaches to understand executive control in young children. | Espy KA | β | 2004 | β |
| Verbal selective learning after traumatic brain injury in children. | Hanten G et al. | β | 2004 | β |
| Characterization of empathy deficits following prefrontal brain damage: the role of the right ventromedial prefrontal cortex. | Shamay-Tsoory SG et al. | β | 2003 | β |
| Dissociable contributions of the orbitofrontal and infralimbic cortex to pavlovian autoshaping and discrimination reversal learning: further evidence for the functional heterogeneity of the rodent frontal cortex. | Chudasama Y et al. | β | 2003 | β |
| Dorsal striatum responses to reward and punishment: effects of valence and magnitude manipulations. | Delgado MR et al. | β | 2003 | β |
| Dynamic functional changes associated with cognitive skill learning of an adapted version of the Tower of London task. | Beauchamp MH et al. | β | 2003 | β |
| Effects of THC on behavioral measures of impulsivity in humans. | McDonald J et al. | β | 2003 | β |
| Error-rate-related caudate and parietal cortex activation during decision making. | Verney SP et al. | β | 2003 | β |
| Inhibitory motor control at five years as a function of prenatal cocaine exposure. | Bendersky M et al. | β | 2003 | β |
| L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. | Cools R et al. | β | 2003 | β |
| Neural architecture of choice behaviour in a concurrent interval schedule. | Kalenscher T et al. | β | 2003 | β |
| Neural substrates of decision making in adults with attention deficit hyperactivity disorder. | Ernst M et al. | β | 2003 | β |
| Obsessive-compulsive spectrum disorders. | Allen A et al. | β | 2003 | β |
| Orbital prefrontal cortex and guidance of instrumental behavior of rats by visuospatial stimuli predicting reward magnitude. | Bohn I et al. | β | 2003 | β |
| Orbital prefrontal cortex and guidance of instrumental behaviour in rats under reversal conditions. | Bohn I et al. | β | 2003 | β |
| Risky business: emotion, decision-making, and addiction. | Bechara A | β | 2003 | β |
| Role of the amygdala in decision-making. | Bechara A et al. | β | 2003 | β |
| Schizophrenia subjects show intact success-related neural activation but impaired uncertainty processing during decision-making. | Paulus MP et al. | β | 2003 | β |
| The contributions of lesion laterality and lesion volume to decision-making impairment following frontal lobe damage. | Clark L et al. | β | 2003 | β |
| Thinking of the future and past: the roles of the frontal pole and the medial temporal lobes. | Okuda J et al. | β | 2003 | β |
| Tryptophan depletion alters the decision-making of healthy volunteers through altered processing of reward cues. | Rogers RD et al. | β | 2003 | β |
| Adult clinical neuropsychology: lessons from studies of the frontal lobes. | Stuss DT et al. | β | 2002 | β |
| Age, executive function, and social decision making: a dorsolateral prefrontal theory of cognitive aging. | MacPherson SE et al. | β | 2002 | β |
| A neural basis for social cooperation. | Rilling J et al. | β | 2002 | β |
| Asymmetric functional roles of right and left ventromedial prefrontal cortices in social conduct, decision-making, and emotional processing. | Tranel D et al. | β | 2002 | β |
| Contributions of the prefrontal cortex to the neural basis of human decision making. | Krawczyk DC | β | 2002 | β |
| Decision-making deficits in drug addiction. | Clark L et al. | β | 2002 | β |
| Decision-making processes following damage to the prefrontal cortex. | Manes F et al. | β | 2002 | β |
| Depression: perspectives from affective neuroscience. | Davidson RJ et al. | β | 2002 | β |
| Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. | Goldstein RZ et al. | β | 2002 | β |
| Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. | Cardinal RN et al. | β | 2002 | β |
| Emotion, cognition, and behavior. | Dolan RJ | β | 2002 | β |
| Evaluation of a behavioral measure of risk taking: the Balloon Analogue Risk Task (BART). | Lejuez CW et al. | β | 2002 | β |
| Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association. | Royall DR et al. | β | 2002 | β |
| Human brain regions involved in visual categorization. | Vogels R et al. | β | 2002 | β |
| Parietal dysfunction is associated with increased outcome-related decision-making in schizophrenia patients. | Paulus MP et al. | β | 2002 | β |
| Self-control: theory and research. | Strayhorn JM | β | 2002 | β |
| Studies of altered social cognition in neuropsychiatric disorders using functional neuroimaging. | Grady CL et al. | β | 2002 | β |
| The role of rat medial frontal cortex in effort-based decision making. | Walton ME et al. | β | 2002 | β |
| The role of the amygdala in signaling prospective outcome of choice. | Kahn I et al. | β | 2002 | β |
| Two phylogenetic specializations in the human brain. | Allman J et al. | β | 2002 | β |
| Adult sex differences on a decision-making task previously shown to depend on the orbital prefrontal cortex. | Reavis R et al. | β | 2001 | β |
| Affect regulation, brain development, and behavioral/emotional health in adolescence. | Dahl RE | β | 2001 | β |
| Beautiful faces have variable reward value: fMRI and behavioral evidence. | Aharon I et al. | β | 2001 | β |
| Changes in reward-induced brain activation in opiate addicts. | Martin-Soelch C et al. | β | 2001 | β |
| Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. | Bechara A et al. | β | 2001 | β |
| Frontopolar and anterior temporal cortex activation in a moral judgment task: preliminary functional MRI results in normal subjects. | Moll J et al. | β | 2001 | β |
| Functional imaging of neural responses to expectancy and experience of monetary gains and losses. | Breiter HC et al. | β | 2001 | β |
| Hunger selectively modulates corticolimbic activation to food stimuli in humans. | LaBar KS et al. | β | 2001 | β |
| Impulsive choice induced in rats by lesions of the nucleus accumbens core. | Cardinal RN et al. | β | 2001 | β |
| Integrating orbitofrontal cortex into prefrontal theory: common processing themes across species and subdivisions. | Schoenbaum G et al. | β | 2001 | β |
| Neural activity associated with episodic memory for emotional context. | Maratos EJ et al. | β | 2001 | β |
| Neural activity in the human brain relating to uncertainty and arousal during anticipation. | Critchley HD et al. | β | 2001 | β |
| Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. | Drevets WC | β | 2001 | β |
| Predictability modulates human brain response to reward. | Berns GS et al. | β | 2001 | β |
| Prefrontal, parietal, and temporal cortex networks underlie decision-making in the presence of uncertainty. | Paulus MP et al. | β | 2001 | β |
| Prefrontal regions supporting spontaneous and directed application of verbal learning strategies: evidence from PET. | Savage CR et al. | β | 2001 | β |
| The emergence of social cognitive neuroscience. | Ochsner KN et al. | β | 2001 | β |
| Changes in functional connectivity in orbitofrontal cortex and basolateral amygdala during learning and reversal training. | Schoenbaum G et al. | β | 2000 | β |
| Control of response selection by reinforcer value requires interaction of amygdala and orbital prefrontal cortex. | Baxter MG et al. | β | 2000 | β |
| Impairment in a discrimination reversal task after D1 receptor blockade in the pigeon "prefrontal cortex". | Diekamp B et al. | β | 2000 | β |
| Multiple reward signals in the brain. | Schultz W | β | 2000 | β |
| Organization of connections of the basal and accessory basal nuclei in the monkey amygdala. | Bonda E | β | 2000 | β |