Genetic models for the natural history of smoking: evidence for a genetic influence on smoking persistence.
paper
Cited
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- Authors
- Heath, A C; Martin, N G
- Year
- 1993
- Journal
- Addictive behaviors
- PMID
- 8465673
- DOI
- 10.1016/0306-4603(93)90005-t
We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking persistence, accounting for 53% of the variance. This genetic effect on smoking persistence is independent of genetic effects on smoking initiation.
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